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<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2H5</accession>
    <name>A0A9P6E2H5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_779012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158243">
        <property type="protein sequence ID" value="KAF9521229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2H5"/>
    <dbReference type="OrthoDB" id="3149508at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="35"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="28565" checksum="F7E5F99F9723EC38" modified="2023-09-13" version="1">MEDDPADNDEGWEDDDGDEGVNKQRFSPLEDGFGNKFVNVIDIAGLVPLPMVCCQCNGGGIVNQLLDRRLLPVSFKSPRTMFTFRLLKDFRLSNLEAKTTGYQYYQKLRRVTNPAFPHLVPNRYPELRRASRMWRNLMQLRWNGFGYSARHREADEGQTMLIPGPGELAMFCAACPQPGINLPDNWETRYTKNEVMRTLVVDGNFSADHLRQKQADLDVFLSEGQGMMTARHPYKDHLAVARDEMEVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2W5</accession>
    <name>A0A9P6E2W5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conidiation protein 6-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_256253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158037">
        <property type="protein sequence ID" value="KAF9521518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2W5"/>
    <dbReference type="OrthoDB" id="5419162at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052670">
        <property type="entry name" value="UPF0654_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36576:SF1">
        <property type="entry name" value="UPF0654 PROTEIN C11D3.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="137" mass="15304" checksum="6D7D8E4516F81F44" modified="2023-09-13" version="1">MILNIRKSEPQKGGRNLYIFWKVWEVFNQNRISTLTINQLRFTHTSKFTMSSTRQAGGFKAAMHNPNVTEEGKQAAAEKLQNLKQSGELESTTASRTEGKNEGNVIGGYKATLKNPNVSEEAKDHAKEILEEHGVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3S5</accession>
    <name>A0A9P6E3S5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_152349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157970">
        <property type="protein sequence ID" value="KAF9521967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3S5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="116" mass="13082" checksum="88900FBE0B88031C" modified="2023-09-13" version="1">MNLYTSSCGGLPNQNTTHDLLQPPLTKTYPSLLHSVETSCLPMRLILEQRLTDMEIKSPDSRYPIILRELYAALLLAVTLSCTNIHVKKMQLNSKTLLHNRKSTANGAEARRCMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3U5</accession>
    <name>A0A9P6E3U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3U5"/>
    <dbReference type="OrthoDB" id="3236755at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="35554" checksum="4661972B610E59D4" modified="2023-09-13" version="1">MASFDGALQACLRCSSPDQEGLHIFGHAKHRAKATSTSFGCIQQSLLRNKQIRLLRAIIIPTSKPTTWTSRSYFNTHQMKTLLLLLMLHFSYPQTLAQILELYQVPTHQTEQDMEACEIALVADHVDRSMAIEALPDITEEQNNALKETVQSLLGPDLYDVSACRSYHPAVLVLDLKVLGRLVLLRLHDEIETSEWNNLYINNATLQFEIHLTQFIAMGDPFARAIQCLEATSAGPGDVFLYWIAIVARIKRLRAIFNFNNPNSLQLNIKIPAQDTSKSKYRTVSSLQQILSSKLANTFTVVPHYAQLSSAKSSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3X3</accession>
    <name>A0A9P6E3X3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_736599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3X3"/>
    <dbReference type="OrthoDB" id="2142724at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8779" checksum="777B5B153877A10D" modified="2023-09-13" version="1" fragment="single">VNILTTYRTNGWALKGLPSGLIYSHIKKGSYDGDQFMEWLEGLLQMTSPYPAPNSVLILDNCRIPHVEGVEELCAARSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4Q9</accession>
    <name>A0A9P6E4Q9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157942">
        <property type="protein sequence ID" value="KAF9522533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4Q9"/>
    <dbReference type="OrthoDB" id="3244593at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="376" mass="42669" checksum="261222D4715C1AEE" modified="2023-09-13" version="1">MPLTSSLRTTTQELGQRLAEQRARSQLAAPRSPASPSSNVNQNYGSAPPLTPATPGRHQNNEDAFSNSPTTTLGRRRRSNAIGKWTPSTKMKLREYGDELANEEGLNDEHRELVITSSGLPTHKLLIQFMAFQLGQYQVQTDDGFAQYLKSPTFRENVTDSLRSMLLSPNLSSYKNGFLERALRHIHLNPRQYKFNVRYEPQITSQAFASTISTNLTHARAQIKKKLADGWEKKTDIHVLTKSLTFKGTHEIEEGALARIAWIQLHSIDFNEEVLEGKKKAVDFWDHIDQKLADLREEYKNEPEADRRAIISVHFTECLNIHQTNCRPLKKFKGASQSNIPAWQKALSRAIDAMESYTQEELAGEDDDFDEETSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E582</accession>
    <name>A0A9P6E582_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_747908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E582"/>
    <dbReference type="OrthoDB" id="3045137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="26"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="134" mass="15044" checksum="5EFF21B56BF86FBA" modified="2023-09-13" version="1" fragment="single">AMHDSSERDLPPSCHPKTRLKVIETIIAWIEDADPLVDILWLHAPFGYGKSAVMQTAIGILIFFGLRHLFAGAFFFGRNKPGRDLARYLFPTIAYQIAINVPGMRELIDHAMVLDPTLPSKTMEIQLCSIIIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5H8</accession>
    <name>A0A9P6E5H8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5H8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23142" checksum="7830979760EE6804" modified="2023-09-13" version="1">MSYQPRPTTNDHEPTTTDHNHNRSNQELVTSTATTLPQPSSRSHSRKTHPQPQRRTPTTTFQQRPTASVPISVATSHPLPQPSNPTHFPNQVISNDEPQPSNLRYHQPPYNHPTNQPTTNDHNQPPYQPTNNHNHNRNRNRSNQELGTSPANSHHTSIVSASVPVTVTVTVTTNDQSGKVAKWHRQESGGVAEWRSGEGAKAQSREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5I3</accession>
    <name>A0A9P6E5I3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_887277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5I3"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="292" mass="33281" checksum="612F218AA196516A" modified="2023-09-13" version="1">MANIIFFGETGSGKSSLVNMILGYEAALTSNATHGCTFQSDAYSTSINGVQFTLHDTSGLDEGEQGRVPHADAIVQLYSLLKRLNGGLSLLIFVMKAPARIRDSTKSNWRLFTEVMCRSNVPNALVITGLEQEANMDAWWPANQEHFRLNEIYPSAHACVTAIKGKMKRNGSYILQEEYDQSRKKVQDMIIATRRYDPWRMQTVEWLNQVVYETYYESRACRSSIERKRAVDTIRGAEEDLIGRLIGAILRDYKVDSQLPREMKVTKYSNLHCRDIRDRPLIAPSRQSNFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5I6</accession>
    <name>A0A9P6E5I6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_732038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5I6"/>
    <dbReference type="OrthoDB" id="3221808at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="13963" checksum="15C094F13221C372" modified="2023-09-13" version="1" fragment="single">WKVVQEYYTTREEVRCDAWKDEVQHLLIFSGLFSAVVTAFLVESYKALQQDPSEVSVLLLSRISVQLDSLSNATQTSQIPALSGPPLSSSRRINSFWFLSLVFSLTSALVSIVAMQWIREHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E663</accession>
    <name>A0A9P6E663_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_694988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E663"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16837" checksum="865FD0D9564FBBB3" modified="2023-09-13" version="1">MSSLQTQNANESSVHVLSHRNLWCAATPSLNFYYIDGFLIFATSGAALMKDLVSALLSDPYPFERKRVILSHVQVSQTSTQECLHSSQYFDEAFLTEAALNLTLRLRFKLEVSPLLDLADRASSKPLACDNLLDCYATPAWNERQLHPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E715</accession>
    <name>A0A9P6E715_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_650552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E715"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="18026" checksum="03E7D182CEDFBB24" modified="2023-09-13" version="1">MSITLNKVNFYLIKRCEVAFKYIRSKTGKYLLHLSLPLNLTRFDACGLSTAKQPIAQDCRYIHSSSSNTHLRCRFYPQSFNAFRNVGSTYMVIQAANVIVPDLLPSGIRELIQLIQQDGENKLGLIKWMSELDKVMTPELHIGAFSYRRHLFRVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E776</accession>
    <name>A0A9P6E776_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_821126</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Preautophagosomal structure membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E776"/>
    <dbReference type="OrthoDB" id="10003551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000150">
        <property type="entry name" value="Ubiquitin-like protein ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <keyword evidence="5 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="111" mass="12380" checksum="736334FF1340B724" modified="2023-09-13" version="1">MAETPQPAIAEVVLDSYKLKDPTNKVALRFKAVGNAPIMKRNEYKIIAQNKFQAVIDFLRKELGRPVGDPLFLYVNSTFLPAPDDTVVNLYNSFATNGFLIVNYSTTPAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7K2</accession>
    <name>A0A9P6E7K2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_839458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7K2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040449095" evidence="2">
        <location>
            <begin position="23"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="12015" checksum="70A0D1C2D0631C18" modified="2023-09-13" version="1">MVSKFTSIIAVVVLALAAQISAAPLAAEVIQERDIAPNGGLTNAKRMALGLPLNPPTRRDPNGVKPPPHPSHLPPPPPPPPPPKPTKPPHWPPPIVIPIPIPPLPLPHWPPGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7N1</accession>
    <name>A0A9P6E7N1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_750385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7N1"/>
    <dbReference type="OrthoDB" id="2790258at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="90" mass="10353" checksum="43CF151BA6DFFB18" modified="2023-09-13" version="1" fragment="single">LLTVLEKAHSAQELLSAEKTPTLSAALPAFELLLVAWTNLQKEIPEISHYIVVSVMKIREYVEKSRSSRIYALAIMINPAYKMDWINEHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7P6</accession>
    <name>A0A9P6E7P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7P6"/>
    <dbReference type="OrthoDB" id="2863512at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040145843" evidence="1">
        <location>
            <begin position="20"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16165" checksum="E82F86F88A20C808" modified="2023-09-13" version="1">MRFFTAATAVIAFVCASTATPVPGEAKSVSGVTKRGNGDEIIYLVTCNGQPHASRAVYYAHWHDSQTYGAHAPNAISYGNGNLGPGGYSSPGSTQYIFLDTKLDVTLNNLDPGWYQVAGSATNQFGTSFTCRMDNGRQLYSDCFSNYYCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7U5</accession>
    <name>A0A9P6E7U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7U5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="35564" checksum="F413BCFDA1E2692E" modified="2023-09-13" version="1">MRQRKLGCLRIYSGRAPYFDQAFGQQTQQVIMDLVSDIHSLQLKDIVIPAAFMEKLPPLKYIYLRNVSLTSPGSLSQVPPPVFTDTSDFDVGSLQGISQFYQRSQQPIPAYVNFAIEFTPLFLDHSSLPDMLSGSIHSLRSLIIHPPILKNENHFRLELGAFRKLTSLQLKLRTVIQQSAWEVLLPLNLQLASIATVLGFPTPPSKLVNVSLEIELIGTPRSLEGCTHLLSSAELVNGLDRKDLLPKHPELKLITIKICPPQTNSFWEDRQDNHLFLAFKNIVGRYIRKVLPNSHHVRKQELGRAIVHNISLDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E832</accession>
    <name>A0A9P6E832_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_774118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E832"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="51"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="489" mass="54087" checksum="D2912BA9857F233B" modified="2023-09-13" version="1" fragment="single">QWLGQHISAGSIHDSAERSFSGPPARCMPGTRKSTLDVIHRWLDDLSAPSKILWLSGAAGAGKSAVAQTICEGLKQDNRFVEVDFFFSRTSTGRNNAAFLFITLCYQLAIAIPLLRQCIEVILKDNPTLVTKTSDIQLQKLIIEPLLSIAIEARPRNCVIIIDGLDECENEATQRRLIQEFISAYQNIDFPIRLIITSRPDPWIRENFKKGGPLIYAITLEHTDEANDDIRAYFLNGFEEIRQRTPSTHGQDTGWPSKNQINLLVYRASGQFIYAATVLKFCGDPDFSPPEQLRLILSTPQHASSPRNPLAELDALYLQIMASVPDKQRTLDVLGALIAVLNVTSGKSGGVSLLAKLPASSFNGGELLDIVEDLLPIAPGASYIALRRLHALVRVPEYAETSRNAPSDPSVTANPDLGRLIKFHHQTFPEFLVDPKRSEGYWISLRVAHESMGISAMNLLSDCALEMTGLENISRGISISGSKLFYCIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8K9</accession>
    <name>A0A9P6E8K9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_798007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8K9"/>
    <dbReference type="OrthoDB" id="2533496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="98" mass="10874" checksum="A8FC1E9BB6CEB32E" modified="2023-09-13" version="1">MAETQTAPTTIEINDAIFCQSHLKEICSDCSFDGREENDGFYGFDTADRDGIECPASTLNKDGVYQCKKHGSAECNQCYGWKKQITRARVAAKKAGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8P7</accession>
    <name>A0A9P6E8P7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Osmotin, thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8P7"/>
    <dbReference type="OrthoDB" id="3002175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040215270" description="Osmotin, thaumatin-like protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="20238" checksum="05CB5B36E374EBD7" modified="2023-09-13" version="1">MFSKITQITLLLTLAAATARGSLLSNELQSRQTPPPTDRQYIVVNNCPTPIDLYIGTLKDNTMPTHGKITKFSQNFDVGPFWSDINSGSIGGSTRVGFHDDYYYVIAGFSLNVGVHVEASPRPPNSGFCIPIDCQHLPCSNTFFFPPPSFPEPTEGPPPSPYFRCPLHNETFTITFCPSGSFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAC7</accession>
    <name>A0A9P6EAC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_772315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAC7"/>
    <dbReference type="OrthoDB" id="3221235at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20648" checksum="60F4EC1E870CB122" modified="2023-09-13" version="1" fragment="single">MEPEIAALVPTNEAPSEELMTRVRGLLAKPLQEIDQVDKEIQRLENNLNAIRDKRIKTQQLVHSYQAVLSPARRLPHDILREIFLHCLPANRNPIMSASEAPMVLTRVCSSWRAVALSSPRIWARLHIPFPGNAFDTSSPFGSSDRKLATENPKYVETMKRRCEVVEQWLLRSGDCPLSISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAP1</accession>
    <name>A0A9P6EAP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAP1"/>
    <dbReference type="OrthoDB" id="152248at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040353890" evidence="1">
        <location>
            <begin position="21"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="220" mass="23610" checksum="73927E9EE71EBBA6" modified="2023-09-13" version="1" fragment="single">MAKILTYTFIALVCTLGALAIPQRTTIPSDPAPVITDPPVAGFNITSLGVNGSGCPPGSTYYALSEDKTAVTVTFSEYYAVVGPGYPISGNRKNCQLTIGVQVPGGFSFGIATIDYRGYYQLDKGVTATQQSIYYFQSQLAQATAHSDLVGPVDGEEYTYRDSFDLVSTVQSPCGINTLLNINSDVRASNRQNPKGTGYVATDSIDTSLTQTYSFQWQKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB13</accession>
    <name>A0A9P6EB13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_908915</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB13"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040431140" description="non-specific serine/threonine protein kinase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="321"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9525816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="647" mass="72592" checksum="BD9D9BFCC4D568C0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECE4</accession>
    <name>A0A9P6ECE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_770346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECE4"/>
    <dbReference type="OrthoDB" id="3259646at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.660">
        <property type="entry name" value="IL-4 antagonist (De novo design) like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="143" mass="16013" checksum="E93C30D6F24D22F1" modified="2023-09-13" version="1" fragment="single">TPEGDSDMPVRLQCLGASFYHCFQQTYDLTDITAAIRLAEKAVMLTPEGDSDMPVRLQNLGASFFHRFQQTHDLTDIAAAIRHQEKAVMITPNGHPMMYICCSNLANCFSHRYKITGDDADKSNAEKYEQQAQSLDVNSNLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECG8</accession>
    <name>A0A9P6ECG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECG8"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040384928" evidence="1">
        <location>
            <begin position="26"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="563" mass="64864" checksum="5EBAB190D78529B5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECI3</accession>
    <name>A0A9P6ECI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_858023</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECI3"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="11">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="120"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="224"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="32110" checksum="EA02A82DF5DFFAE2" modified="2023-09-13" version="1">MAGDHKCPVCQATFTRPQHVARHMRSHTGDRPYKCQYCGDQFARSDLLSRHVNKCHANEKPMPSTGARRKGATGASRATTSKQACDQCVQSSLPCDGCNPCSKCISRKSRCTYVKFHRQTAPVGPGHNTRPNAPPSSVLTGSLPPPSSLSTSASSSSRLPLYHHGDDDFILGPAPSAVPTMAEALYQSNTFAFPALYPHNDVGGLPDGSADYASKYRAQQAELFGPGRSGLGTGLTPLYDPRPGSSSSSSSWMSGWDGQDSHETYQPQSHRTSDYVSASAPSASTLHGNHFYPLSARYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECZ8</accession>
    <name>A0A9P6ECZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ammonium-dependent carbamoyl phosphate synthetase</fullName>
            <ecNumber evidence="14">6.3.4.16</ecNumber>
            <ecNumber evidence="5">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Arginine-specific carbamoyl phosphate synthetase, ammonia chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Glutamine-dependent carbamoyl phosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">CPB83DRAFT_857533</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="14"/>
    <dbReference type="EC" id="6.3.5.5" evidence="5"/>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECZ8"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000004">
        <property type="entry name" value="Carbamoyl-phosphate synthase (glutamine-hydrolyzing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000015">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009455">
        <property type="entry name" value="PRK12815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF53">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="21">
        <location>
            <begin position="207"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="21">
        <location>
            <begin position="744"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="22">
        <location>
            <begin position="1008"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF9526633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1161" mass="127652" checksum="542F844809F0DAEC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDN8</accession>
    <name>A0A9P6EDN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rgp1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDN8"/>
    <dbReference type="OrthoDB" id="1918at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08737">
        <property type="entry name" value="Rgp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="854"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1078" mass="115247" checksum="83975C0D249BB4C5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDQ0</accession>
    <name>A0A9P6EDQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_857201</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="10"/>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDQ0"/>
    <dbReference type="OrthoDB" id="21243at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000050">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000238">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034762">
        <property type="entry name" value="Lys-tRNA-ligase_II_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF9">
        <property type="entry name" value="LYSINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039101">
        <property type="entry name" value="LysRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="280"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="40"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="635" mass="71535" checksum="18C3A65293506704" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EER3</accession>
    <name>A0A9P6EER3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EER3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7614" checksum="86CAA7B65816A181" modified="2023-09-13" version="1" fragment="single">TKLTCYVAKLALFYLAFVGGGGRELDSSVFIPTTSVVGMFIVHRGLYLWVWMFKGIRFVLTTSSSMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFG0</accession>
    <name>A0A9P6EFG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFG0"/>
    <dbReference type="OrthoDB" id="2986469at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040330275" evidence="1">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="14411" checksum="1AA1608D10E69B34" modified="2023-09-13" version="1">MLFQTITLFAFVASALGGACTPEQLALHAVTGGQQTAPYSRWEHVPGSDGKEYGIFDSRDATEPACTFDASIAHSPGVSRRKLSPLVAGRAPACLGDPCTNAQFCINEGCTHGCASWTTPGYPGEPGQGFNSACISDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFL2</accession>
    <name>A0A9P6EFL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carboxypeptidase C</fullName>
            <ecNumber evidence="2">3.4.16.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_883737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.5" evidence="2"/>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFL2"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="499" mass="56597" checksum="374E5D18D0DA2D9D" modified="2023-09-13" version="1">MLNTSAALIGGLLYSQAAQQIPFTTSFQTSVQVQGPFAPLGNLSLLAQDSFSVLEHPEIPDYSIRIKKSQICDGLVDAYTGYLDAGSRHSFFWFFESRQQPENDDVIFWTSGGPGGSSARGVFMEIGPCRVLEDGKTVIHEESWVSNANLFFMDLPAAVGFSYSDDSKEVVPVETVALDVNAFLIIFFEHFTIFKGLPFHFAADSYASSYLPAFATTLLDQNLQLEAEKRPLTPINLSSLILGNAMTDFYTMIPGYYKMACTSTSGLKLLDAQTCMQMRQALPRCQKAAQEACIRTTNATKCEKASNDCVEQVFEPFWTYGKGRNPYNVKTNCKNGDPDSCPTFILAPFASQVVKHLNQPELREQLRIDPVFESYKWDNLEDNEFRNQLDLYHDTFFYITALLERNVRILSYVGKDDFVCNWLGNEKWTRGFEWYGRKDFRRQPMRKWKVNGHLAGKARKAEDGALMFTVIDDAGHVVPRDKPKELLELIKKWMKHEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFT6</accession>
    <name>A0A9P6EFT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFT6"/>
    <dbReference type="OrthoDB" id="21418at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38645">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38645:SF1">
        <property type="entry name" value="YALI0F12243P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="34936" checksum="969D9336FA30866E" modified="2023-09-13" version="1">MESLNLNTLASSLPAGQQNAEKELLNDFKAAALSITKLYRSSRKTSKRAYNAGYGAACQDLLTFIQQGVSAGDVGQAASAGSSQEVEGGGMTIGRVMDRIEARLEAIRATEEDEDEDEEREKDKERPVAPGTTSRAPAVAPATPSSTKIVAKKLPSQRSKDTAPPNNSNTRQSSEHSSSSLSPPPSAPLALPSKTLKMRTLPSHSTSSNGTPHRSEPFPTTNPSTPVSFSEPPPIVFNAGTKRRHAMMMMLDASSPTLSISPGTASSSSTGSPATGPGSGSVIGRRRTRSSRNIGQHQSQNQNINLIQVASEAMDIEEDGRERKRVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG47</accession>
    <name>A0A9P6EG47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_735438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG47"/>
    <dbReference type="OrthoDB" id="2576233at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="853" mass="97582" checksum="F408B43ABCA98775" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGI4</accession>
    <name>A0A9P6EGI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_305204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGI4"/>
    <dbReference type="OrthoDB" id="2758429at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="489" mass="50270" checksum="6E8BD88B9264D4A2" modified="2023-09-13" version="1">MSRVRTSVSVPSNLRFGVKTSNSNTSMSSTSGPSSGTTNRMDNNINAFQPNQQQPDKRVSFAPHAPTSATSSTTPPAISTSTSSAPLAKPPPPPTSNSNTTSSSSAIPKTVSSLNFKAESQESDDYGFDDDEFAAMAVEADLADLGQPIDGHTDLGQPIGDEDVGRPLDVEDVGRPIDMEEGTLVSLADGRESEDVGGVVGVHPKVRMMQQQQQSGERCGEQQQKRGGQGSNASSEPSASSSSRAAGTGLNRSLSRDEQIKAALNGPVKDGPVSGSSCTTSMRAASTSGSGSTSSNSTGSMRPPPPPGTGSGSSSNSRLLMGTSSLLSMTSSMAPPTSGSWAQTRHRQYLDKKQLQDQNVHPNQNPNPSGSGSMAARPVGEIAGGGGGGVNGHESVSKRSMGGGFNFPPGVNVPALTSTPIIGVKRPADALLSYSSSGLVGSNSNSKGRPGMGLHNQNLNQQTGGYSQQRQVLGSLEVGEGGDVKRVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGT1</accession>
    <name>A0A9P6EGT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E1-E2 ATPase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_894177</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGT1"/>
    <dbReference type="OrthoDB" id="3040189at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="4">
        <location>
            <begin position="30"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="177" mass="19418" checksum="73F900FD61E3D41C" modified="2023-09-13" version="1">MSGYCRRYTLASFSQPTSKARTRQDLVSGIALIEPGEIIPCDGIFISGHNVKCDKTGITGESDAVKKLRYSDDIDLHRKSDGQDAIHTDCFMISGAKVLEGVGKYLIVTIGTKSFNRRIMMALRTDTKDTPPQIKLNNLAELIAKLNSIAGLALFAALMIRFFVQLGQDIHQKTPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGT5</accession>
    <name>A0A9P6EGT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGT5"/>
    <dbReference type="OrthoDB" id="70224at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="2">
        <location>
            <begin position="171"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="39012" checksum="DF82FC30449D3C8A" modified="2023-09-13" version="1">MKTEATKFSAEDYFATQTPPPTLEEDVEKVREFVKIQAKEGRNIVLVTSGGTTVPLELNVVRFLDNFSAGTRGATSAEYFLKAGYAVIFMHRQFSLQPFSRHYSHSTNPFLDFLDIESQDSASDPTPRISVTPEKRADLLTVLTSYKRVHSLGLLHTLTFVTVNDYLWLLRAVSQELSVLKRRSMFYLAAAVSDFFLPRQKMSEHKIQSGKGSLHIEMDQVPKILKPLVDEWTHGGFIVSFKLETDQNLLLPKARQAIERYGHQVVIGNDLHRRKFEVVFVSKKAASQDLTSSSQEDPFEEQWLRIPQSVVDQTTPGFPIKEIEEDIVQELIKRHTLWVKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH47</accession>
    <name>A0A9P6EH47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL lipase/acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_766100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH47"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040496349" evidence="2">
        <location>
            <begin position="23"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="35838" checksum="74900DF93CE3B3AD" modified="2023-09-13" version="1">MFSRAFTLISSVVIFAIYPAAGQPYNDGTKEVTLGQIKNLVTFGDSFTDILSTSDGRTSWPIYAASYANLTLYPYAHAGATCSNNLTHLSSPSVFESQLPAYYNDTSTGTIHLSPASTLYTLWIGTNDVGLKSLLIGHDSASLVDVTKCMVNWLQDLYTRGARNFLFQNMIPLEKTPLYSKNSWPNRYWHLERNTTEWNVFMRELTLSGNELTSLMLQAIVPTLHGAHIGIFDTHSLFADMSSNPAKYLNGTAALNVDDAVNKCVYELNGGPTTNCTTIQGTDRDSYLWYDELHPSEQAERIVAQVIAQVAMGEGNKWITWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHU8</accession>
    <name>A0A9P6EHU8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Golgi CORVET complex core vacuolar protein 8-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_893451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="289913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059070">
        <property type="entry name" value="TPR_VPS8_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25066">
        <property type="entry name" value="TPR_VPS8_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="3">
        <location>
            <begin position="856"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="domain" description="VPS8-like TPR-like repeats" evidence="4">
        <location>
            <begin position="1399"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1614" mass="179846" checksum="926C793559AB1C69" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI37</accession>
    <name>A0A9P6EI37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acid phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_267691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI37"/>
    <dbReference type="OrthoDB" id="2865258at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="47581" checksum="90390DFDDBB29849" modified="2023-09-13" version="1">MAWYPKVVGLDTDWTIWQNYLGMEYWGKGPGAASTSQDNIERVDRWTLRDKTNKNMWIKQYNDIANIVYDILKNGAKLAIVSRNRNKEMCDRALTFFNANNPNDGNKEYSIIHLVTYDEIIDQSKVEHWRRIHGWSGEDYSEFLMFDDEAAHNSVRIEVGVTFQQARDKKGLYWDLYIEGLNAWRRAKTVIMHNTPTAPKNRKLIGYSGLPGFWIDLIGKGEGIVEPKTPYRWGYAFYIADYIELAKYFCGWNGTWINDDGSKVCEVWVRDYEAWQSINKVWVPENGGGLIQMNNIHWSYEETGQNQEDRDRIIAGFGVPTPYVLFSRHHWMNGMPVPQPQRWSEMVVYTQVQRALFDVVPLTDAQVKANTNPRPYPFHHQIKEWNITVPSVTWQEFKSRGETDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIV7</accession>
    <name>A0A9P6EIV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_905725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIV7"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="114"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="641" mass="70120" checksum="A5BC2892149FBC31" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJJ5</accession>
    <name>A0A9P6EJJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_198735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJJ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="17158" checksum="7622EA9AFDE17784" modified="2023-09-13" version="1">MVTLSNVALYVKQDLEALLGGAHELQGLHTQISRSSVDIISTFSRMTDSANDHLEALNRSATEIQERFLAQQQLNLWPWRNIAYRFAGLIIRDSSALLGLEHVAWFQLLVASLSGAWSLVYTTSSLILSLGVVILLATRDLCAKNLIKIIRNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKH0</accession>
    <name>A0A9P6EKH0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKH0"/>
    <dbReference type="OrthoDB" id="3268830at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="306" mass="34490" checksum="94CE25CAEF1E52D1" modified="2023-09-13" version="1">MQRVGQSHRNRASNLNSNIGSEKRFSPYKVPPSSPPSRHSPAKRDEDERTQENDVPQIAARSKSAMKTTKTAAERTREQSILNDPLANLLSPYYVECKQCKKQIKLSSKSAYDTFHWRNHRKRCVKSFKKKGKPIKFSVASSPSPVDTSSTAVTITPPHSPSIPTYDSSRDRMTPPLMPDEEDQRSEQSSEVQSPILESHPIPADHPPPSINYYDYNVEDYLGRSHPGYVQRHSTRHLSCTSASTGSHNWSWSQLKPSRFVVEGARYDRRNSADDDCTSDHSSAHSTGDERVQEAARTLSLLSRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKK2</accession>
    <name>A0A9P6EKK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_763031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKK2"/>
    <dbReference type="OrthoDB" id="445826at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="66012" checksum="6E86498969CD4E5E" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKR7</accession>
    <name>A0A9P6EKR7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CipC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKR7"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="11521" checksum="DF0F71280C5FFFC9" modified="2023-09-13" version="1">MNRQFHPTSSTLYVLNFFDNMGWFDDDSDQAAAYDEVMNAPHKSHLSHELIAAAASYEAMKGYEKHVRQNGQPASHEQAKEILAGLSGFFVDKLVETKGVIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKT0</accession>
    <name>A0A9P6EKT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKT0"/>
    <dbReference type="OrthoDB" id="2690420at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="411" mass="45682" checksum="8D54EC5A5EAE1E2F" modified="2023-09-13" version="1">MTLISSNSSPSYQFRIDKDTTQLVDGPVNASTGNIVVTSSSFKGFDHLGHVSPQSHPPAVKMPAPSLSLYKFPFYPAKDEKRLRKELICPSACDQAVTSCSFNGLGHLRFMSNRIPSEPLYYSLNNEERPTTLKFSGVLDLESRATQINPYFGHGASMSTTAKKFEKIKPTFAILPLPQTPSVYSKEAVACSHATVKFLAEVMRTSNIDLHEYAYFTEKDVTSWIYTVVEGGKQGLKLETDPLFVAPGDKTCKHDKTNTAAQLPDPLHYYKHLFHKNPELAKYLVLQPLIKDVDGSVIPPGEYQSRLHDMHLRPVTVEVTPLVSDAIPSKPGQTGKPKYRLVINWLQLLPKPKPIVPPSTGVPSLPACQPLRQRKREVPSDEIVTGKGIVKMRKLNFVKQGPHVIVRDVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELJ2</accession>
    <name>A0A9P6ELJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_849384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELJ2"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="123"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="31969" checksum="C75445DB0FF3866E" modified="2023-09-13" version="1">MAHSHNNVPLRSALKQSSRPASPTNGLASPTMSPQISRIPLPLSPSTSTATLSISRVHSRSSIHDSPSPGPLLQSPQGLISPSYTPKVSFDTFENPVASMFSFTLQVKTEGYRRTRSTRVFLCASSPDESGSEALEWSIESLVQDGDELVVFRGADEDVLQKDHNLVREEARDLMRSIQEKSVEYDPERKLSLVLEYIPGKVTDSLDRLIALYRPDSLVVGTRGRRFGASLVQGLGVGLVQGLGGSGSAIGSVSKYCLAHSPVPVIVVRPGRKLRKAAEKRRANPKRGQHFEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELL8</accession>
    <name>A0A9P6ELL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_849335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELL8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040268497" description="Secreted protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8857" checksum="411D66B45FEA3736" modified="2023-09-13" version="1">MVTVKFFRILSVTWPFLSATGALQFPQGSLLRRRLIHRVLPTALKIAHYQKLSPPFRRTGQGSGNQISLSWSRPILDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM81</accession>
    <name>A0A9P6EM81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848589</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM81"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="25360" checksum="4601BE76F56D31CC" modified="2023-09-13" version="1">MTQLDSQQFDNEIKVNADQRREVDINVKIQNLGINQLNNEVQVDVNERVPPSIRVGALGEDTDIDTEVDQLLLGEREDDIEVNVEEREVGRRWNTVAPDVALEDVQVQVDIDDLGLAELDDEVKVNVEERGNTPWVVWVGWQAVACNEDIGIHIDECRWRGGVEARFTNSVVWSRQSDDYVDQEDRRDGGSKEFEHIGLLCSPWAIRTDLENTEDDCLEICSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMG3</accession>
    <name>A0A9P6EMG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="5 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_849121</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="18">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="18">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="18">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Mitochondrion inner membrane</location>
            <topology evidence="1 18">Peripheral membrane protein</topology>
            <orientation evidence="1 18">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="5 18"/>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMG3"/>
    <dbReference type="OrthoDB" id="1696654at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="16 18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="15 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="19">
        <location>
            <begin position="46"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9531492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="275" mass="31364" checksum="A5C3DA869D33966B" modified="2023-09-13" version="1">MQSLLRATRSSNFANLSHGLPKRAFSTSQRYRQATPQEKPVLMKEFKIYRWNPDEPDKKPELQSYNIDLNQTGPMILDALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGQNTLACLCRIDRDGGKNTKVYPLPHMYIVKDLVPDMTQFYKQYKSIQPWLQNDNPPASGEHIQSPADRLKLDGMYECILCACCSTSCPSYWWNQDEYLGPATLMQAYRWIADSRDTAGDARKAKLQNEFSLYRCHTIFNCSRTCPKGLNPAAAIAKIKLELSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMX0</accession>
    <name>A0A9P6EMX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HIT-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_847212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMX0"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="6">
        <location>
            <begin position="9"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="4 5">
        <location>
            <begin position="100"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="3">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17465" checksum="642B654CE521C0C3" modified="2023-09-13" version="1">MMVEPNSCRFCRVSAENGFDIVYEDALFLGFTDRNPASAHHFQVIPKAHIASVRSLNPASHVGLVQAMEAVGRRILDNFGVPESMRKMGFHIPPMNSVYHLHLHVQGLPYHSTTRALKYPVVRGFGHFSKGPSWFVEVHQAMRILEHGGHIGLLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6END2</accession>
    <name>A0A9P6END2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exocyst complex component sec6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_848705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6END2"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051601">
        <property type="term" value="P:exocyst localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.50:FF:000006">
        <property type="entry name" value="Exocyst complex component sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="751" mass="85858" checksum="32E354290B605F2E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENF8</accession>
    <name>A0A9P6ENF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_593801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENF8"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="477" mass="54804" checksum="37C12DD5376A3C47" modified="2023-09-13" version="1">MDQPGLRYLPTVGSTLPLLSQISCIRFLMDTRKAMEDALSKWPKSLFIVPALCEWVVIATEPALIDDIRKAPESVLSASTALREGLQTDHTVGPHMFDNDYHIAIVRSQLTRSLPRLVPEVHDELIEAFKDYIPLTEDWSTVQAYNIVAKLVSRASNRIFVGVPLCRNHDWIDLSIQYTFDVVQTGQLLRFFPSFLRPLVVKLISQVNKRTKIAFDLLQPLIAERRKEREGKPKEYQGKPEDMLSWIMDEAKGTETDDWHLTSRILMVNFVAIHTSSVTFTHALYHLAASPEYLEPLREEIDNVTSREGWTKEALDQMSRVDSFMKESQRLKPMANYLMNRVVMKDYQFSNGVTVPAGSVVGVMVNHHTSKDIFEEPYKFDGFRFVKMREQAITAGLTEKKFNMVTTGIESLAFGHGRHACPGRFFATAELKLMFAYMVMNYDLRTVEEGVRPKDFYFMQTCIPNMKAEILFKRRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ17</accession>
    <name>A0A9P6EQ17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_415322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ17"/>
    <dbReference type="OrthoDB" id="432299at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="816" mass="91258" checksum="AA98C0C413B11006" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQH1</accession>
    <name>A0A9P6EQH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1212-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_873052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQH1"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="501" mass="54785" checksum="ED6412477C918569" modified="2023-09-13" version="1">MEKNALRSMDYKSRRKHIQRIRIQFNISVMRKRYEFLLKLARALMTFGAPSHRIESQLVAAARILEVEAEFIHLPGMVICSFGEQDLGSSETHFVKAGGRLSLGSLHKVHIIYRAVVHDEISAGTATEQLEALMNSPPPYSVVFRCFLAFWLSALICPLAFGGSFLDMWVAGASAFILCWLQLHVAQKSALYANVFEITISILVSFVARGLSSIRSRIFCYTAISSAGIIGILPGYLILSSSLELASKNIVCGSVKMVYALIYTLFLGFGLQIGNDFYLLLDPVSRRNLDELSTSLSNAVTLTGTWNSENGTVNGTSIPLNGTWTFTHAVLPNERDIIVGCYRPKSFPWFLQPFPMWTSFIIVPLFSFLSSLANLQPLRSKQLPVMVVISCFSYASNKIANHYIFNRSDIVSAIGAFTVGLLGNVYSRKMGGTAFTSMVTGVLFLVPSGLSQAGGITANGNGIDIGGAMIAVTIGITVGLFMSQALVYTFGSRKNAAVFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQV3</accession>
    <name>A0A9P6EQV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_844212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQV3"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="11604" checksum="E9C62F9303696C68" modified="2023-09-13" version="1" fragment="single">MSSSIAACRAVMRLLDFSAGELFIHSISGGVTSSNPPVITRHPLNRPEIRVTTEQITKAEFRLSDGDTPYEENSNGIELLTELHAVKAQDAVGENGEVALDRPQSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER60</accession>
    <name>A0A9P6ER60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_845146</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="11"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER60"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000006">
        <property type="entry name" value="Puromycin-sensitive aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11 15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="14">
        <location>
            <begin position="117"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="12">
        <location>
            <begin position="360"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="13">
        <location>
            <begin position="655"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9533368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="992" mass="111665" checksum="7F722455A3F80F34" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERB8</accession>
    <name>A0A9P6ERB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-xylanase</fullName>
            <ecNumber evidence="7">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_805519</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14 15">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERB8"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031158">
        <property type="entry name" value="GH10_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF76">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00591">
        <property type="entry name" value="GH10_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040445547" description="Beta-xylanase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="10">
        <location>
            <begin position="97"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="366" mass="38419" checksum="CB64D9A99E906AB1" modified="2023-09-13" version="1">MSKLLALVTLAVAVQQATAVAVWGQCDTGNTCNYVNDYYSQCLPGSAGTTPPPATTTPVTTPSPAPTGGGSGLDGKFKSHGKKFWGSCADPGTLGITANVNILKSDFGQVTPENSMKWDATEASRGSFNFGNSDQLVNWATSNGKMIRGHTLVWHSQLPSWVSSIGDKTTLTSVMQNHISTVAGRYKGKLYAWDVCNEILNEDGSLRDSVFSRLLGESFVTIAFTAARAADPTAKLYINDYNLDSVNAKSQGMVALIKRINASTKLIDGVGTQMHLSAGGAGGAQAVLTLLAGTGLEVGITELDIAGGSANDYTTVVKACLNTPNCVAITSWGVSDVNSWRASSTPLLWNSNYQPKAAYTSVIAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERD0</accession>
    <name>A0A9P6ERD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_873536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERD0"/>
    <dbReference type="OrthoDB" id="3230530at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="734" mass="78716" checksum="271B5F4DA19A7FC1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERI8</accession>
    <name>A0A9P6ERI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_214493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERI8"/>
    <dbReference type="OrthoDB" id="3263403at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="47553" checksum="2696AD9D76FEEA63" modified="2023-09-13" version="1">MPGPMVPSPTTQLPYQQQGNQHLPLSYPQFHSAPHDHQLISSNGQATSYPPNPYPPAASSPHSVQYPPNSYSPARSPLSVEYQAQQVPHQSPLHPGSRGSSTPLSLDTSMRPMKVEMPPTPLSASNLHSSSPFSAPMHPRQPQPGERQPSNRMSPRINTQTHHRPPQFGPPQTFPTPAQIQSLNIQEQHPSVEITTMSPNDMYINPPAMDEHQQGYAGPNEYVAPQQRPPEHLEHIQSGSTTPDEPSTHAPLKRNSVTMLEGAEFGEDSQKKPRLDDTSHQTSEQSYDEGSYMSAQSQRMYAAQDGSYGQIYAPAPSEPISAPLLHQSMSTYGMDSGMMYSDANTMEEEDMEYEVEVGPDGLRLVRDCLEEIFRTPEGGGRVCGLCLLRQQRNPNIEPPMPFINASDDDLEMHCLSEHEKAWTIARQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERN5</accession>
    <name>A0A9P6ERN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_831642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERN5"/>
    <dbReference type="OrthoDB" id="3515051at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040277172" description="DUF8021 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="2">
        <location>
            <begin position="154"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="28502" checksum="ACAF367D89C6C07A" modified="2023-09-13" version="1">MLRTILVTTVCATLAAPSLAACTLSQLQDITASYVTAQSSGKLPALASGAAYTENFQAADISTGVLTKPLVISHNRSLHDTVACATFTELIAPNNSPPYVLGSQIRLTDDGTKIKSIDSIITTNGDWLFNATGTLYWSQQEDLKAGWEVIPEEKRDTREVIQAAADAYFDLFDDHSVVVPWGTPCDRLEGGLYTGTGSETDSCNLGVPDGISIVNRRYVVDETVGSVDVFVNFGGASGNPDSHNFRIVDGKIRYVHTMTFGQIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERZ5</accession>
    <name>A0A9P6ERZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_745978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERZ5"/>
    <dbReference type="OrthoDB" id="2141050at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39218">
        <property type="entry name" value="OXIDOREDUCTASE 14 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39218:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 14 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="72" mass="8065" checksum="F72667FFFB4C7234" modified="2023-09-13" version="1" fragment="single">MSLLANIIGFSFFGLGVRFGQLGIQRRNLFSNPGGHLLSMGAFGVIGYYAYQWDIRSGELLAKKRGELLERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESI2</accession>
    <name>A0A9P6ESI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_831680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESI2"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF1">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="23708" checksum="75BD18C22F9E646D" modified="2023-09-13" version="1">MSSPTAHKLATARQKKDTADQAFKIGNTKDALKSYHESLMYLLGLDKNALQSIGMAPKTTETTKDGKVQEKTEVDEIVEKIYANMSACHLKNGNWKRAQETAEKALAKNENNYKAMFRKGKALGEQGFFEKSVKVLEDLKTKNPTDKELVEQEIERLRAIDNERERVHKKKMKGFLNKAEKKGNTLSLEEGSSSVPESIKQGFIEEVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EST7</accession>
    <name>A0A9P6EST7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Patatin-like phospholipase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_844006</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EST7"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="8">
        <location>
            <begin position="158"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="9">
        <location>
            <begin position="278"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="617"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="688"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="773"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="309"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="620"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9534295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="822" mass="93769" checksum="33D5C6B217F8516E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET15</accession>
    <name>A0A9P6ET15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_779742</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET15"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07628">
        <property type="entry name" value="BAR_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06863">
        <property type="entry name" value="PX_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000042">
        <property type="entry name" value="Vacuolar targeting protein Atg24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="13">
        <location>
            <begin position="56"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9535643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="470" mass="53601" checksum="D9C3947F0822FBC6" modified="2023-09-13" version="1">MQGDDDDLFDSVTWESPNQPGYDSAADEGVIPSGPGFRQSASDSNEDPHQPKWEGFLITYVRDPVKELAETKDAYVSYLVSARTNLPIFSTPNPSSRRRFQDFVFLRSHLARDFPACVVPALPDKHRLEYLTGDRFSPEFMERRRQDLHRFLERIARHPTLQRSTLVRAFFESTEWNVTMHQHVAHPPTNEQSQGIIDNISDTLLNAFSRVRKPDERFLSMREEVDKFEEALVLSERLYGRIRGRTSDGNPESGEDLTADYHDLAVAVQGLGFLESGITDPLNHFSNTLLEFSALLRHTTQTTTDPLLGHLHSLLTYSHANRAVLKLRDQKQLDFEELSDYLSGVTAERDRLSAIISGHAGSTGLGIGAYIKDRVDALRGADDDRSRVERMRKLDLKIKELEDAVTTAHETSDAFSDETLREQTIFQHSKEAEMKEMLGHLADGEIEFYRTAMEEWDRIIPVIQRIRVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET35</accession>
    <name>A0A9P6ET35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Small GTPase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_843099</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET35"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="22439" checksum="518C37F8A8EB2AB9" modified="2023-09-13" version="1">MASKVAPKRRKIVVLGSRSVGKSSLIVQYIENHFNENYYPTIEHNVPKTIKLNGIEYDCEIIDTAGQDEFSIFNSKHAIGIHGYILVYSVASRNSFNMIQPLYDRIIDYRGTEDVPCVIVGSKTDLGASQLYSRQIEASEGEKLAHQNHAAWIETSAKSNTNIGKVFELCLAEIEKGAQRNLIAPEPPAPVQTQQTRCIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETC8</accession>
    <name>A0A9P6ETC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_879627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETC8"/>
    <dbReference type="OrthoDB" id="2405700at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038910">
        <property type="entry name" value="Hua1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28031">
        <property type="entry name" value="PROLINE-RICH PROTEIN HUA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28031:SF1">
        <property type="entry name" value="PROLINE-RICH PROTEIN HUA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="494" mass="52151" checksum="3A56DA42CEA8E990" modified="2023-09-13" version="1">MFTAISASQSSKNPFNPFRTNPATPNPTGTQTDGPAEVSNSPKPSTTAPERAASPPIVSVTPSPPIPQQEAFPSDLFEDPPPYTPSPSRVAGETTIEQGPARPFQPPPSRSGNAPSPTGWSRVQNNVLPNHTGSSNVSWSSGRPGGSSRGGSLFQQIASSINTVIQELNSPQSTGSSTLNPQMTGHNTWSSYPGQQRAQQSYNWTPQQGPSVHSHGPSQPARPLSAAASHSDFRAPGGLPPPETTHRRHSSEFTRDFYAAGASGEASLHAEGSGEHAPPLPPRQSTGSSSATPRDGKPTSNPVAGHPLMNMGRVLVYPRGHRCEKCQNIGYKGADPNRPCNRCWNKYAKPFTGPVALSFSNTSDVQGESNLQRPLPYQPPSTPRPSGPPGLISHSSYSGPSGGYQRPPPQQWGTQQPGGNNLNSSAPHAPSRPPLPPRAIPSFGNRAPPGAIVYTAGDPRIGGQLCWRCNGKGNVSFLFDRITCDVCNGLGRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETY6</accession>
    <name>A0A9P6ETY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_754526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETY6"/>
    <dbReference type="OrthoDB" id="3063971at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="61458" checksum="AEACBC8A11C0F12F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUZ3</accession>
    <name>A0A9P6EUZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUZ3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="19589" checksum="B3410285A595B373" modified="2023-09-13" version="1">MLDTPPASGTPRRYPARERVKTRSKENSAPHPYNTGKRSAGRVSPSRSRSNNIRKPLLPTQTGARPKDKRKHGSFSNEETTADDNTLSIKRIRKLISDDNTTNVTAGSSDSPSDEESEHDIDSNLRECIVNSARQYFQEYLALRNFIPNVNKDLHKASACLSNPSICGTRVENSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI00</accession>
    <name>A0A9P6JI00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_751457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157975">
        <property type="protein sequence ID" value="KAF9521911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI00"/>
    <dbReference type="OrthoDB" id="3265515at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="9145" checksum="92235FA3646F7C39" modified="2023-09-13" version="1" fragment="single">VVWTPGHEGLVGNERADEEARKASEEGSSRERLLPKYIRKPLPHSQAAVKAAYRKELLERAKGQWRKSRRFDRLNRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJP3</accession>
    <name>A0A9P6JJP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_863206</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJP3"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="286" mass="30477" checksum="99F79DD1BBE4EBC4" modified="2023-09-13" version="1">MPTTTPENLEGSFQALLQSFAMIIVSEIGDKTFLIAAILAMRHPRLIVFMGAFGSLVVMSVLSAAMGHLLPTLIPRSWTQFAASVLFIVFGAKMFMEAREMKAGNEKIQEEMREAEEEIQEDEAAVEGSASTDVHGTGRSIPLEQLEAGVRASTRSRSPTSSGASDKAGLAEGARNFCSLFLGPVFVQAFILTFLGEWGDRSQIATIALGAAHNVYLVTIGTVAGHACCTALAVIGGRYVSTKISVKHVTFGGSILFILFGIIYLYEGFVTSREGISISTEGVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJU9</accession>
    <name>A0A9P6JJU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-related protein Arp5p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_862527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJU9"/>
    <dbReference type="OrthoDB" id="7340501at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="781" mass="88258" checksum="0548DC893B4AF5E5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKC9</accession>
    <name>A0A9P6JKC9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKC9"/>
    <dbReference type="OrthoDB" id="3267648at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="480" mass="54880" checksum="EBB76671777BC677" modified="2023-09-13" version="1">MPLSKTIILSLAHPPKISELEIVPDPWVSSSNKILKIDLSLNEHGPRYEPEGEQLEDFESQAFHDELGNLIEEQKSCPTLVLRTTSREDLVMRNEMLARRLRKIVAQDCALPKTERIDAVEIGPDPESYAYSALDGISPKHIKLSSGFAEEIHAEEIENLFYPWEEIESAEIVSECMGWHWNSFLSPKGSITHASAIAFPEFISRVKSLQLTYCHQFRFRAKHLPMEMVNFKIIGNDAMSAFCNAFDNIPGFNDRLQRLHLASNDSQCESGDAFDFKERLQECTAIRDLFLALGDQPRPIAEDSLGEQSPGSTSLTGTVYDMPLDDYHDGEDEDIEGFDENMANVSEDETFNAEKERRQHLPGRPTGRYWNYFYEVNQSERDNDTRLSLFIPSSIEFLSFHCSSSDAMFKDLDYWIDAAKNDTWLPNLKQITIRPDGPLIDRLMEKKVEGNEKQLKDMEAKIEQIYASLKKRKSRVVVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLT9</accession>
    <name>A0A9P6JLT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ectomycorrhiza-regulated small secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_567495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLT9"/>
    <dbReference type="OrthoDB" id="3144234at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="58"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="24463" checksum="26625B5554D42801" modified="2023-09-13" version="1">MPTVMPVPVVRPSPLYKQQGLPSSYSPPSRTMSEDEFYLHSLLRYYQQEVIPGYVCPIQWDVRDPPETARRVVSLEDVIGPFHLSRPATSPPMIVLHITCDIFPEAWPIEIRKLDTITINDVLHAIHSSLQRPIRRDEWERLSEKQHTRIEAVFDTRCKNAPNRDECRSRGVLRVDCLLQHTVYAGLSVSPDADCSCFLTLRRPHQAGVSTTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLV6</accession>
    <name>A0A9P6JLV6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_819013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM170 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLV6"/>
    <dbReference type="OrthoDB" id="2131401at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019334">
        <property type="entry name" value="TMEM170A/B/YPR153W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779:SF6">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="21374" checksum="41E6370055F1799C" modified="2023-09-13" version="1">MTSNTTPSWPSLYNPGVEILHITHHPPTNPRGSYLYRAGDIFRFTLYWTLIFYIPLFLVCGFYAFWNYAFPPSPKDIRETNHASVASEHQMSPMLPITQRKRSVQQITRPLKPNERRSRVAFALIVLFTFLTLSLAGAVTGSAILGIVTYGLFKSANFHMSTWIPFLLAVMQVLIGLLSIWPSIIEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNG4</accession>
    <name>A0A9P6JNG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Maltase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_908140</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNG4"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040236545" description="alpha-glucosidase" evidence="10">
        <location>
            <begin position="30"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="12">
        <location>
            <begin position="177"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="11">
        <location>
            <begin position="339"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="13">
        <location>
            <begin position="768"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9526788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="983" mass="108680" checksum="8F98239518D9987B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNN3</accession>
    <name>A0A9P6JNN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNN3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="441" mass="51560" checksum="765FE270A08914B6" modified="2023-09-13" version="1">MKLTHPNIEDFNSFRESVRSIGRTFLLKTGKFNYEHAESDWRSFLNSVSSEQPLLAHYEDSWPTEYYYNYLRSRRKEKAPRKQIEVPEPAQVIARPEGKKLFFRLLADLEQFMKNTHPDRASFERFTKQVKIESRKIEAKYRSEQDDAVWDGFIRSMMAIDSSLQRYEDAWPLEYYFNALVKGRKDSRNRANRPRVRKRRETWRALCPIQATPLNSSPQPISSQAILHDRETTTQLEEKQTVLLAPCFFCHGSPIAEPSFARNLGAFLEHDQALIMELARLGVSQDNHLDFLLSLPPIFLERTIVSIPTVQLSPISKCRLLDLFERHRNSQQLATRSDKNSRFVLLRTPCRTHKSLDTPDTTFFLRDELHTLGLAELIPALAHMEIIDETMFAHFKQMGDKQRLSLVDKYHLHLTDFHFFMIGVSCGSKLVRETGWVSFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNV9</accession>
    <name>A0A9P6JNV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNV9"/>
    <dbReference type="OrthoDB" id="2885496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="395" mass="45268" checksum="1325B8761C1196C2" modified="2023-09-13" version="1">MNQADGIDSAWERTRYLIKLEGHRALRKGSVFDPGDIACCTGSLQSIFYRHLEQKTILLNAWERNRKIQGPTRYCIVNRKLQNGSYEVFVMTTFGQARLFEDLGLIARKYGIPLGGMKWPEEIRPIMTYPAAFGWEKKSFIFGIPTVVPSLLPASTVRAIRLVPGELQRLRDISLRKLKTIRRDHRSIRDSLKNRKIDKFGAGESPTDVNQDDFLRSNDVDDDLGDLEPYLWNGQPIPRPKKRFRIRSARRLLPRRHDITWVLRFASDDLLSFSTYLSQRGIHRKGSSWMSRLNGQHTNSPLLPASYYAPSLRANITPKYSLNAKSEASRLELPQVSARSLSSNQMPSAPLFIPTLTLNSTSSFHRTLSPRKTLLHPVPDLLKRSLTTLFRRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP92</accession>
    <name>A0A9P6JP92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="13">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_876420</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. PP-2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="13"/>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP92"/>
    <dbReference type="OrthoDB" id="5593063at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07416">
        <property type="entry name" value="MPP_PP2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041751">
        <property type="entry name" value="MPP_PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="15">
        <location>
            <begin position="177"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="519"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="627"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="550"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9527434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="652" mass="72753" checksum="5ED5FDAAD09BC546" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ21</accession>
    <name>A0A9P6JQ21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MICOS complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_297957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ21"/>
    <dbReference type="OrthoDB" id="2399148at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019166">
        <property type="entry name" value="MIC26/MIC27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033181">
        <property type="entry name" value="Mic26_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268:SF1">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09769">
        <property type="entry name" value="ApoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29010" checksum="C130FCDB9610580C" modified="2023-09-13" version="1">MFRTAIKPRRAVLSAAVAGTVVGGGVSQQSDKLSIYPSATPDILLVDSPSELENQIGVARRQAQSVYSDAHAEVQSWVAKWIGVEHAVEYRVKSIIAKDEPLTPGALYVGVATLTGSIIARNRFLPTRLLLPPIFLIASAQHFLPKTSHNLSAYLGSLEDRYFPSVAQTHDIAKAHSAMTWERVKDATKDGRASAGKAVTSAVDSIQEATGLKLRETFGWQKEQVHILEDKVETFKEEVGKKVKEEASKIEEEVGKHIDEVKSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ39</accession>
    <name>A0A9P6JQ39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_854199</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ39"/>
    <dbReference type="OrthoDB" id="205099at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="11">
        <location>
            <begin position="51"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="684"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="684"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9528468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1126" mass="126818" checksum="A25B259F8DBEDD44" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ99</accession>
    <name>A0A9P6JQ99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_765079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ99"/>
    <dbReference type="OrthoDB" id="412109at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="55"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="234" mass="28068" checksum="8B765DCAE63A7B49" modified="2023-09-13" version="1">MHKASDSLETETVYFTTGSVNGSRTTSRSRRNEWEELIYVYEVEAENWIKQEEKARKIANEREKARLRIQEELRRIEARYQQKRDAERIAREEARRRDLTELKEREKRDRAKRERLTADAWTRYESRWSSLSSSMVPLDFKSTPWPLILSPRSTDDITQDAIAAFLFSQTHSQDQSRRDRIRSAQLRWHPDRFRRFLGRVAEKDKVIVEEGVNIVARILNELMEKEKKKGYYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQG5</accession>
    <name>A0A9P6JQG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQG5"/>
    <dbReference type="OrthoDB" id="2548233at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034:SF1">
        <property type="entry name" value="CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="523" mass="59175" checksum="18EEB903FF2CB985" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSE6</accession>
    <name>A0A9P6JSE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lipid phosphate phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_875149</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSE6"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="101"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="33640" checksum="0BD1AB83E9A98DCF" modified="2023-09-13" version="1">MSKVRELINRHFGPDALVWFDRAYLVDWVAVTGIWVLSQLVSWSPVYERKFSKSDPLISFSHRKNQVGSATNHFLALFGPLAVFFVVGALKKNLLLIHHAAIGVWASRGLARLVTQVLKHSVGRLRPDFLARCKWNHVMETCSGKAQDVIDGRKSFPSGHSSTAFSGMVFLSLWIAGQTAAWCFSTPKSPGRLRSSRIALFLLTLFPLFWATHVAVTRIQDHRHHKEDVIVGSFVGILSGLICYLIFWPSPFHASTFHFENYGQPRILYTRDDYGRPRVTEFELAQSRLDEDGENTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSP2</accession>
    <name>A0A9P6JSP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_849956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="411857at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="476"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="570"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="7">
        <location>
            <begin position="1054"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="1075"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="1110"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="1146"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="1353"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="891"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1405" mass="155439" checksum="B746303FE3725377" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT10</accession>
    <name>A0A9P6JT10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_100817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT10"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="38251" checksum="467BF8E514B90B6A" modified="2023-09-13" version="1">MVQNGGTKMQLKPFNTDTPFLYLDPATGNLVPFCQYIVVSSFSIFLFDLLDSFKDDYQHVVQQRFCFMSVVFVISRLSCLTFLLICCFILTAPLGDQCERTVFVVATVFIFYRASTCALFYARVKAVYPQNRLVKAAFALLWCFAVGGAISSIFSVTAVRIGPTMYCIPATVGLWELVFMVAAEGIYDLLVCIAVTYKVREYRMAEDGELDGACGPWLWFSPSKRSRLADRFLRDSQLYFLITACVKIPEILVILCFSIIIPSASGISVVLVYPDTAVTNILATKIYRNMKLRRPGLLPLRRSGVGSTFANLGGRSNPFLFFTAILNKTSTTNEIPLSQIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTK3</accession>
    <name>A0A9P6JTK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_904303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTK3"/>
    <dbReference type="OrthoDB" id="621413at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051476">
        <property type="entry name" value="Bac_ResReg_Asp_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46630">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46630:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="787"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="867"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1039" mass="115234" checksum="7D884C7146B88C46" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTV2</accession>
    <name>A0A9P6JTV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_832002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTV2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040276799" evidence="1">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="16153" checksum="13A5F2F98FDF6D50" modified="2023-09-13" version="1">MKLTSFFGLVFAGLATALPAPDFDNVADDIIISTMAHSDVTVPKLTVPPGATIVTPNSPFRALDPSRVDSIILCVTASCTNCYAFTLSTLAKNSCYTTSIAFSSGFLYTSSNGTPANVYVSTTINIKCGNAYSLPVNTCGYLPDGPQGNAFFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU76</accession>
    <name>A0A9P6JU76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_627411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU76"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="12943" checksum="29CDBF63DE34B522" modified="2023-09-13" version="1">MARSTPTPTPLIYTMYSLRHLYGKLIKLASSSNTRRTGKLCEVHMAALEETSRFGKIEGYRTFALLALEIAKHQEMFNELGLRFHFRQHRTTMCLRFESQRKLPGNLVRGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUH8</accession>
    <name>A0A9P6JUH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_844013</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUH8"/>
    <dbReference type="OrthoDB" id="3638488at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21773">
        <property type="entry name" value="MobB_CBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000192">
        <property type="entry name" value="Serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF76">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_135, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="123"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="425"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9534302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="56159" checksum="681BF50AEA5B2C75" modified="2023-09-13" version="1">MANNQQPYSTRPTPPQLKTAPSSGNLNSGKEPSDYVYFDRNLNGLSTEAMPRAKNAQVKLEHFYKVAVDAAIERNTRRVELERRLQNEHTMSEERKNRQLSQLGKKESTFLRMRRTKLGLEDFRTVKVIGKGAFGEVRLVQKTDTGKIYALKLLKKDEMLKKDQLAHVRAERDVLAQSESHWVVQLFYSFQDTVNLYLVMEFLPGGDLMTMLIKYDTFSEDVSRFYIAECVLAIEAVHKLGFIHRDIKPDNILIDKDGHIKLSDFGLSTGFHKQHDSSYYQRLLENPGNKSAQNARNSVMVDSINLTMTNKDIATWKANRRKLAYSTVGTPDYIAPEIFLQKGYGKECDWWSLGAIMFECLVGYPPFCSENTHDTYQKIMQWQDYLMFPEDVHLSREAEDMIRRLITSADKRLTVEQLKNHYFFYGVDWETIRQIDAPFVPHLRSVTDTSYFPTDEIDQAADSGPADPNAAGKDLAFLGYTFKRFAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUN9</accession>
    <name>A0A9P6JUN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L22/L17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_758201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and at least 33 different proteins. The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and at least 46 different proteins. uL22 is associated with the polypeptide exit tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUN9"/>
    <dbReference type="OrthoDB" id="10254664at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000012">
        <property type="entry name" value="60S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00065089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21260" checksum="B0B178FF81DB58C2" modified="2023-09-13" version="1" fragment="single">IVRYASAALATNPERTARARGEYLRTHFKNMREVAAALSGMKLAKAYAYLGDVKDHNRVIPFRRFAGGVGRASQAKEFKATQGRWPEKSIKFIGRLLKNAESNADAKSIDVEELYIRNIVVEQAPKTRRRTYRAHGRINPYQGHPCHVEVILSATDEEVEKATDKSASLSLTGLNRRQVARRRIEAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVD8</accession>
    <name>A0A9P6JVD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_409310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVD8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="18230" checksum="368B56EA7AA08DD6" modified="2023-09-13" version="1">MEADQNHQKELEARVEALQEALTKEITRVEKMKMITDAWRQEVVSVQSKLDEALQQTAYQTAEIERLTVKYSKLEHSMSMNSNQWIIPTIQASSGHKASASPTITEELDFLAKCEAKLPQQLSDISSTVPAIGQSTFSSSTVPNPVNISQTGHSLPLTYEIVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVT6</accession>
    <name>A0A9P6JVT6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_843005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVT6"/>
    <dbReference type="OrthoDB" id="2260578at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="219"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="28373" checksum="C7115F2505B98D45" modified="2023-09-13" version="1">MRNTSISTSGAGPLDIYKRRSLNGHVITEPTSTQSKLVMSSSNVHTTKRRAQIACTNCRERKVKCEHENGETCKRCAASNKECHYEPVSTDKAPSSSPYPSTSMSHTSTLDGGFLVEGVRAPPSFPAQSSFSQMPVAAVHSQQASMPAQQYPTYPQTQTHTTQHPSPNHFHQYSQVSSLPSYSMPAQNPMAVPAPSQSWQTPQTQYGYGYAQSSTTQQIQPQNWPNIPQPNVGTQIAGYSYPMQPNSFNQQRPHEGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW32</accession>
    <name>A0A9P6JW32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_755073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW32"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="15659" checksum="23236E408A2D60B4" modified="2023-09-13" version="1" fragment="single">MSPSPAPLDERHSFTIPNFNGRSSRNNREPSPEPLTDVEVSLFRQRAVDLGSTTSESAAGFSNTANNLSEREKELVEMVLRLTSSPLVDATQLEQQAAVISRLTLQREYLIAQADEEREKWQSEREGWDRTAEALLTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW73</accession>
    <name>A0A9P6JW73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Glutamine synthetase</fullName>
            <ecNumber evidence="4 13">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_843921</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="4 13"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW73"/>
    <dbReference type="OrthoDB" id="1936100at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.70:FF:000004">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000004">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050292">
        <property type="entry name" value="Glutamine_Synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852:SF57">
        <property type="entry name" value="GLUTAMINE SYNTHETASE 2 CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51986">
        <property type="entry name" value="GS_BETA_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS beta-grasp" evidence="14">
        <location>
            <begin position="22"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="GS catalytic" evidence="15">
        <location>
            <begin position="108"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9534245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="39226" checksum="3A7F37A07C887598" modified="2023-09-13" version="1">MSNLYHNDLLAPYLALDQGEKVQAEYVWIDGDGGLRSKTTTVSKKVTDIGQLRTWDFDGSSTNQAPGNDSDVYLRPAAIFKDPFRGGDNILVLAETYNNDGTPNRTNYRHHTAKVMEQAKEHVPWFGLEQEYTLFDADGSPYGWPKGGFPGPQGPYYCGAGTGKVFARDLIEAHYRACLYSGINISGINAEVMPSQWEFQVGPCEGISMGDHLWMARYLLVRIAEQWGVKVSFHPKPLAGEWNGAGCHTNYSTKEMREAGGIKAIESAIEKLAKRHEEHIAVYGDDNDLRLTGRHETGHIGSFSSGVANRGASIRIPRHVASQGYGYLEDRRPASNIDPYRVTGIIVETTLLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWJ5</accession>
    <name>A0A9P6JWJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_755303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWJ5"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9535129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="366" mass="39204" checksum="C6CA9FE9465178D2" modified="2023-09-13" version="1">MKGIWLDVDPGHDDATALMLAVNFPNVDLLGVSTASPPSLGKTHGNAAASHTAINAARCLVAFGANSRILVYPGASQPLLLPAKHDPEIHGEDGLGGVEGLPDPEDPRVSALFAKTDDGSSVHAIEGMAKTIKSAWKNGQGHKVTIISTGPMTNIALFVTVYSSLLEAVEEFVFMGGGVGMGNRSAVAEYNILCDPHAAQIVLNVAVKKTMIPINVTHTAIVTREIHSRLLSPDSLFSVTSEHLPKAISPLRHTLSTIISYFASAYASTFGFAEGPPLHDALTIAYVAHPELFSLTRHRVDIELTGTHSLGETIVDVWKYKSVDDTWGRDGKNCLVADNLDVKRFFELFLDAVMRCDTISSLNSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWK7</accession>
    <name>A0A9P6JWK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWK7"/>
    <dbReference type="OrthoDB" id="2637024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="26578" checksum="89808F9DD9ED3BA3" modified="2023-09-13" version="1">MREEQPPPSTKQTHICSVDSVWVEFSSFPEVEGFFPPYTSIQKLQTLKTPSLPRLPFSSFIRLQMPLRRTVSMPNMQVRPVKTVVYNMTSEKSPEWAVQPRLPSYEEVMDQVPRGEFANGRLPSFKKSFSARYHPYKRPALKRKDVTDRFMNTIFDPQYEPLNVPPPRPGMSSIPPLEPNCELMIQALKQRLREIEFARRAHRLNAVMKEFVEGVRLAHLNLHAEQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWR2</accession>
    <name>A0A9P6JWR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_841596</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWR2"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000171">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="145"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="196"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9535338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="23874" checksum="6D4D1B2CF1FF4652" modified="2023-09-13" version="1">MPKAIISPSVLASDFGQLSAECKRMIKSGADWLHMDIMDGHFVPNITMGAPILSCIKKGVPEIFMDCHMMVAQPEKWVDDIADAGGALYCFHIEATDSPLPLIAQIKARGMKAGVAVSPDTTSAAITDEIGEAADMLLVMTVYPGRGGQKFIERCVPKVAELRSRFPNKDIEVDGGVSPATVGVCADAGSNVIVAGTAIFGSKDPGQAIKSLKEAVDLAQARLHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWZ2</accession>
    <name>A0A9P6JWZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_842128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWZ2"/>
    <dbReference type="OrthoDB" id="10248513at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000039">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.13, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF874">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="5">
        <location>
            <begin position="218"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="373" mass="41653" checksum="128DADB9CBD1A6BB" modified="2023-09-13" version="1">MDLPVINLDVFLAGPKESEAVINECKKAADALIIYGALVLHDSRVSEEDNQTFLNLMEDYFNQPEAELKKDERPELSYQVGVTLENTEKPKCAVDEPCLKIIEKLDPAERPLDISAHSPDPKCRFFWKMGDKPPYETHFPSLNAPNVVPQADFLKEKWAPVMEQWGVSMKSAVADLADMVALGLGLRVETFRQAGRYGPHILAPTASDLVKYGKKDTILAGFHSDLNFLTIHGRSRYPGLNVWARNTGKRIPVKIPPGNNLLVQAGKQLEHITGGLVKAGFHEVVVNDQTLATIGQRKISHPDRPLIRISSTFFWHLSSDYDLIPIPTLNEKARELRAQHFNAGKSDGDETEYPHIKVGQQVANELKHIALMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX90</accession>
    <name>A0A9P6JX90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX90"/>
    <dbReference type="OrthoDB" id="1872379at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="27827" checksum="669B50C017321F5C" modified="2023-09-13" version="1">MSDTEQPTTVKLDLEVSVEAASECKQEGNDHFRAKRWDDALATYRSALAYLPKRSFKKEVIIPSNEPGSESDDVDSGESLAKNRPEESQDGKDNDTIVISTPEVEQEEKEIQKLRAVINGNIGACLIKLGQHKEAVEVCSTALLDDPTYVKALERRASCNDILGTWSGLTAAQEDYTKLLTLITSASQQLDIRKKLQALKPRLESAQKKETDEMLGKLKGLGDSLLGNFGLSTDNFKFVPNEQGGYSVNFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBG6</accession>
    <name>A0A9P6BBG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_741942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158234">
        <property type="protein sequence ID" value="KAF9521233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBG6"/>
    <dbReference type="OrthoDB" id="3214502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="22061" checksum="DB324ECDCD2F851E" modified="2023-09-13" version="1" fragment="single">FCPACPQPNRNLPKNWKWDLIQWIYLRYFVIDGNFKADHVRQKHPGTDIWLGRGRGMMPDPDHYAAFLKEALEKATKAPCETHFRAIEQALLASKACDITGVIAVACARHGCYAPGSLCNLFKGEQQKNADYSLLRALDTTDVDPQQGIMIMYDIACQYCVHLRERIGHLLPRALNIDRAIGLFHVHGHKDQCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2X1</accession>
    <name>A0A9P6E2X1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158033">
        <property type="protein sequence ID" value="KAF9521529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2X1"/>
    <dbReference type="OrthoDB" id="3255541at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1156" mass="129814" checksum="0E1035560674AB18" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3C4</accession>
    <name>A0A9P6E3C4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_887855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157994">
        <property type="protein sequence ID" value="KAF9521740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3C4"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="51856" checksum="AF8F170CAD4914B0" modified="2023-09-13" version="1">MSTRSAALDYAKVVAAWPQVHVKSRKMSRKKENEGRTQKTFIIQEEYLVKSQRQTKRIDAPALRREARVYLVFLSLISGLYYTFLTSVTTKEYYLSDFEMAKTLMTHLTHTLLEPPWLFDRFFYTIAKLDEQLAARHSLLTQLNTKHDPMGNRLPVEITSKIFQHCLPDLPSPETFENSSRESNTDHEFSQTTAKLTSINQNWRSIAHSTPELWTSIFLNFTRWSISGDRLPIILTNVKQRIQRSSNLLLSIRLIAGEGHALVSYSAQMLEAFSLEAHRWRSLCISAPRKVISVISTQTFPKGPTNSTIVSFLDFLPRLMTLECQICNGDQTFNSNPPLLHPSLKTLKLTAIEAVPNLLAKITLPALETLICRFNSNEHTTLRDFLSRSSCPIQTLSIIMPCSEQELIDILLLTPGIRHLPIQTQITSRFFSISRRDCLPEQSLTHLSTSPSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3D2</accession>
    <name>A0A9P6E3D2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_174266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157990">
        <property type="protein sequence ID" value="KAF9521774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3D2"/>
    <dbReference type="OrthoDB" id="3054237at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12265" checksum="B98A2D824168A0AB" modified="2023-09-13" version="1">MVELSNSSGKKKTRKIHPGEALGILPSPTPHKNKNTRRYKRGNLDAILRVRGRLRNAFPGLSVTKPAIRAAYKKAGWPTNEIDWATKREIKVAREHEEAARETYMNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3J4</accession>
    <name>A0A9P6E3J4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157982">
        <property type="protein sequence ID" value="KAF9521850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3J4"/>
    <dbReference type="OrthoDB" id="3031173at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="400" mass="45631" checksum="1BC8F5C7208211C7" modified="2023-09-13" version="1">MPTKPEKGKYSLFSDEMDTRIQAESLLAQPVGDADNFLVQYKLFSSILITTAETVFGTCKLCPKTTKNLTNGMIQLIVGKICATGSAINIAKCGPSTKASDLARRIYFTAMLDHEHNDPCNLKSKEIMLRAKKHDQWRIQHALKGSTKFLNASSFDFIPFPLIVNNLDDPHKLKAYRPKSFDNFKKKLQTLLKSGVKYKPEKYIRLDTDLLKDQMLQILDKNRDLLAFICPQMPEQIHQDLVCGLDSIYPGILVHTNTKSKGKFGKFPAVHHCIYNRYCKSGTCRRRDPAMLQKEGSQHHVNIAMSVPHASVEMKKQLEEYIQLQCVFKPLFDWITELLEKILPDSFEVLSKYIDILPCAEPVVVYPFSGFVINFNVATRLHCDWQDHDICLVLAIMDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3M9</accession>
    <name>A0A9P6E3M9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157973">
        <property type="protein sequence ID" value="KAF9521933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3M9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="27787" checksum="82AFD14A905A75EE" modified="2023-09-13" version="1">MTSTLSSAMLDPMSAGNANSYSYPFLDSSVSIGTQIPQLALAFATFDQVASLTNKLDNLTSFLHTQNQNQQLLHQHPCAGCFQPASPGPEYANHYMDTLIPPNIVRDNAAIILTPSNTICKKEDIFANAVFRYTILPNYWEGQQMEIIARGAHIDVQNLCMQPHITTISDFPPKEVVYIVENTQHLFSHMSYVWVGVYHHNGQRFFGYDAQWGDIILSFSTAQNDTIFPAALSVHALRLIRDSWSSTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3Y3</accession>
    <name>A0A9P6E3Y3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_141409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157961">
        <property type="protein sequence ID" value="KAF9522104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3Y3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="15502" checksum="C769D1758541CEC0" modified="2023-09-13" version="1">MWHAACMEFLYTNTSIPQSHHRQPRHLTAVGAFRIPTHQLALDLSNTQHSVINCPSNFKSSVRVNFGSEAPTRVMQYDDYRPRSLLPVSTNTSGAKRSMPMPKIPYARRVVLIRSSVVGGGLIVASAAYGPSNLRGLQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4A9</accession>
    <name>A0A9P6E4A9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4A9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7713" checksum="D622829E252D78B9" modified="2023-09-13" version="1">MVEVSYHHVYHISLMIIVNLKIITGLTTLTRIKRKSAGASGQWYWQSSVTSGRYDASWVNALLTTVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4I2</accession>
    <name>A0A9P6E4I2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_735259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4I2"/>
    <dbReference type="OrthoDB" id="128646at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="67" mass="7484" checksum="D7D4698762028A12" modified="2023-09-13" version="1" fragment="single">PIKVFNVDGTKNKRGLITHCADLLLEVNGRTVKTRFHVAGIGRQKIILGFPWLTDQNPDIDWGKGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4I8</accession>
    <name>A0A9P6E4I8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_864457</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4I8"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040206781" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="19"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="225"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="551"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="552"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9522419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="589" mass="63079" checksum="F9035CC93675779C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5A8</accession>
    <name>A0A9P6E5A8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_871861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5A8"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF58">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="28184" checksum="24CE9DE5C92F97AF" modified="2023-09-13" version="1">MKTVLQLPFNIYIKTAFNAAEEVAATRYVEENTSIPVPHILDYIPLNTPEFPRMGFVIMKAVSGHPLGQKGELLHEFTQEQKDTFVGTLRSWLQQLRSLAPVNKHQISGFLGGGLVSFRIGDVLDGPFGPFHSQDEFHAQDFCTPWAANNRSLTCALEHRLKTPYKICLTHGDLTPSNILIDDSGCPVALIDWETASWMPEYWEYTRALYMRTDYIGWREAFDRIFPCYGRELTVERAIWEHWVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5G2</accession>
    <name>A0A9P6E5G2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_776389</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5G2"/>
    <dbReference type="OrthoDB" id="3221608at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000007">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="11">
        <location>
            <begin position="39"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="98" mass="11061" checksum="65F7B73A19B5215D" modified="2023-09-13" version="1" fragment="single">RRLQGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDSVTYTEHAKRKTVTALDVVYALKRSGRTLYGFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5G6</accession>
    <name>A0A9P6E5G6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5G6"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="41381" checksum="907648228BEA76F3" modified="2023-09-13" version="1">MARRIIVDDTSDRIIYSQDSAWGDSGVVQPNYNTLNFGPPYGGGVHATSASTLLWFAFSGTSVEVNGYNDVSQSADWTCTVDGTPIDGKSKMPFDNGLTFCQQPNLPDGPHNLTVQIYRIKNRWFWFDHIQYTPSPNANLKDKAFIYQNDDQDLKYGPGWNTADGTTKTNQTGSTVELEFNGTAISAFSRLPAEFFESNSMPGSYSLDGNSSKSFDQSGHLNLDKASYNQQLFQSSTFAPGIHKLTVTYLGDTDHNPLFLDYLIVENYPTAYAAAAAAAAADAKAAADAAAANAKAAADAAAANAQAAADAAVHAKAAKAARIKAGTIAGAVLGGLALLWLLYLCRSVIGRAIRNLCSGRTRSTTANLDEWDDAEKPPAYQPARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Q3</accession>
    <name>A0A9P6E5Q3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_863553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Q3"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="650"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="745"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="801"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="805"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="901" mass="100646" checksum="B17CCAC02D5ED835" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7E5</accession>
    <name>A0A9P6E7E5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_774777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7E5"/>
    <dbReference type="OrthoDB" id="2770090at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20487" checksum="A0AF22BB96B68E9F" modified="2023-09-13" version="1">MTSSTLTSVYRLFLRTVSVSVLHQRSACLNLRRRWRPVFDAAAKVSLELQNVPAEAAQAYRLERLAWLVDWNKRIDNTLALLYNSANTRGLAHQVTRNLAHLAGLERVRALASTRRLPKWNPQGATPSQAKLLKTLEIKRLKAQFVANGLGAMNELVRVAEGSAGLAMGRQDFVVRRWTDQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7L2</accession>
    <name>A0A9P6E7L2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_774834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7L2"/>
    <dbReference type="OrthoDB" id="2591256at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040116453" evidence="1">
        <location>
            <begin position="28"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="763" mass="83281" checksum="DEF01FDA94D4CDF3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E876</accession>
    <name>A0A9P6E876_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_898050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E876"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="72"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="671" mass="76147" checksum="CB5548011EFFADE6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E901</accession>
    <name>A0A9P6E901_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADPH:adrenodoxin oxidoreductase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_877584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E901"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055275">
        <property type="entry name" value="Ferredox_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="60092" checksum="FE93619F92252D57" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E974</accession>
    <name>A0A9P6E974_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="14">ATP-PFK</shortName>
            <shortName evidence="14">Phosphofructokinase</shortName>
            <ecNumber evidence="14">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_860540</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="14"/>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E974"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000007">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000008">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03184">
        <property type="entry name" value="Phosphofructokinase_I_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000533">
        <property type="entry name" value="ATP_PFK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="117"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="458"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal catalytic PFK domain 1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interdomain linker" evidence="14">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal regulatory PFK domain 2" evidence="14">
        <location>
            <begin position="458"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="140"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="170"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="216"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="351"/>
            <end position="354"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="584"/>
            <end position="588"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="622"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="629"/>
            <end position="631"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="689"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="715"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="797"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9524827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="836" mass="90846" checksum="7DB47F80D07DEF44" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAE4</accession>
    <name>A0A9P6EAE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_555505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAE4"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="61"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="114"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="119"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="23343" checksum="FBB2CC57379EB4B8" modified="2023-09-13" version="1">MFTDLNVAPNRPNYPTGWEAGSFTKVSFTVPDNWKAGRIWARRNCNFASNPGPNSCLDGGCNGGLQCDIHSGTGVPPATVAEWTLQGDGNKDYYDVSLVDGYNLPMRIDNNKGCPVPSCAVDLGPNCPAPLKGPYDSSGFPVGCKSACVANLSGNPADSPNCCSGSHSTPQTCPSSGVAYYSYFKGNCPNSYAYAYDESSGTALFTCDSNLKADYTLTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBA7</accession>
    <name>A0A9P6EBA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_941258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBA7"/>
    <dbReference type="OrthoDB" id="3025297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="198" mass="23049" checksum="105F034679A1651F" modified="2023-09-13" version="1">MSSFDESVLDLIPTLFPDLTILAIQWIDGNKRFSLPWKDRYIFSLLKDKNLVELTLSNDFKQAASDPCRGDNQFAWLLRSYTRRLEGARLVCQSLTWLRQCNWLQVCVGANPTTTMLHPFNVEERPNSRTIDRVVRGLRQWWMGTNHEPFSGGEKIELTMAKLEFLPGEVIGEDYSDSERELDYDSDSDELQRNLRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC25</accession>
    <name>A0A9P6EC25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_769770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC25"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="708" mass="77777" checksum="493833BE78112B9B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDB6</accession>
    <name>A0A9P6EDB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP/GTP exchange factor Sec2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_794228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDB6"/>
    <dbReference type="OrthoDB" id="5560525at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="3">
        <location>
            <begin position="227"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="493" mass="53382" checksum="DB34163BF212E5E3" modified="2023-09-13" version="1">MFHYPSGRASQGSNGNIRRADVLNATQQRPSTNPIFLKIEEELHDARRVHSDGQEDDLRYALNMVINRVTELSSMLSEAYKAQAELEVQLNVTKSNLKLVIANNEMLEDALKQNTTQSKDVGWRRTSTRQNGELPSDPRATLERSQSVDLPVTQEPSTPQSAGAASTTGTTSQDNRFFKFRFSTGPSAPAQKPNSNTRPGTPVAGNPGASTPNLTSPSMPSLSSVKMKEVEDLTAELEKEKAERKKIVEEKAALEDELESLSQALFEEANKMVSDERKARAEVEDELKELKAEKEALRSALRVIEGENTNFRSVNASALPSPQPPHSQQSSTSSTDLNTSPTSTPTPTENLAAQQRVHTRSSSEIAIKSRPQSLNLSPTFPPLPPSEPASPSSSSYYEGLPGEEDVRLKNKGSLFSPDVTVLSPEDESQPTPRFGIVSDGSAPPTTGGLRTNNGGSDDDMYLGSSAWADIPSVWQPPKSAPATSRTVPSTLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDN1</accession>
    <name>A0A9P6EDN1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_816386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDN1"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF14">
        <property type="entry name" value="DEHYDROGENASE ARBD, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="29411" checksum="23820ECBDC47F1BA" modified="2023-09-13" version="1">MAAKTSPRTLPSLSLEGKVCMVTGAARGLGFEFCRSFLQAGSTSIIILDLKETETKAAADELAIFATEELKYTAAEIKFIGIACDVSSEESVKKAFSVITQEYGRVDVAVACAGIVENYSALDYPADRAKRLFDINVHGVFYTAREAARAMIPNGGGSIILISSMSANIVNVPQLQTPYNASKAAVKHMAASLGVEWAKDGIRVNALSPGYMLTKLTKTILEDDMALKNTWEKLTPMGRMGEPEDLAGAIVFLASDSSRFVTGSEIRVDGGYCAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEB6</accession>
    <name>A0A9P6EEB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEB6"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="503" mass="54757" checksum="644FD393D38024BE" modified="2023-09-13" version="1">MSFPNHYGQYSGTNEMYGSNPSTPAQQQLQDSFPQWETIDRHHQLDHHSPLETTPLPTPSSANFQMHLEGDHEDPGPPPMVVPSQTSPVDDTPILLHPPTEVPHIHPPPRRPGPTEMHPIDALIFRPPGSSSSAASTPGSSGTAHASSSKPSGVVRTNQTTRGRPPSSHPYYRPSVTQVGIGASFVAPRHAGSSTANATMTTRAQAKKQNVRFAGATPQGGMVPRPATRTTSGSSSMPSPTQRVGFFGGSATNSPQAQQHHSFSPQDSTHTPDTPQMHQFPQTPSTQAQPRTEAQNPPAQHVASSHRRRAHSSIPSDMHYSESDNILTASLELPGVTPDNLRVTLGTCYFNHVKYVGVSAESSPPFGPPEWSAEVLQAVRAEMEKGLAGVTAAGMERLKFLKLSTPQEFRLLQDQPLLSPQDPDLEFFHRPVFTQLILSSAHRDRNCLPQIRFYNLHPHFPLFLHPPPANPCLYASPYALYALATKQPIIFAPHPAPSYSFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF56</accession>
    <name>A0A9P6EF56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_814022</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF56"/>
    <dbReference type="OrthoDB" id="2758521at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040335445" evidence="3">
        <location>
            <begin position="27"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="35150" checksum="05B07F9854B932D5" modified="2023-09-13" version="1">MIPLLPLSALLLLSLSLSFLVTPVFALLENRTIDDSYGDSITGKKVIYKPQAWNDQSCPGCAIHPATSGAFNKTYTAATYHPTIGSISIEMEFKGIAIWIYFILPNNAGDQITTLCMANFTLDGRLSGYFEHRPDMGTTATLYNQLVYFQTGLNSTDHKLLISTSGVDESVFISFDYAVYTTEATSTQNTSTSSANFPSSTPSQVDKPGFGANTARSTATSTAQPSKSTLGPGTVGGIVGGIVGGIVIVVFILLLFLIRRCRPRRHQRTAIKSKWISWPTNPTYVWQDTHGRTFSLDSAHNIIFQDRPPPFEIHHRDQLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFA0</accession>
    <name>A0A9P6EFA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hsp70 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_310923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFA0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000545">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040492491" evidence="5">
        <location>
            <begin position="19"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="564" mass="62148" checksum="3E722AA51E0303E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFJ4</accession>
    <name>A0A9P6EFJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_363502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFJ4"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9527982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="117" mass="12955" checksum="43638F60BD54B56C" modified="2023-09-13" version="1">MAQPLINPNYFEFDFDLQVQVSAARINRRALQTLPLSNVMGTETTPGTAAVPKDASDRVWGDWLKLTYISNTHAVGTCAMLPHDLGGVVDAELRVYGTKNVRVVDRRRSCHSKSVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG68</accession>
    <name>A0A9P6EG68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPX2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_883743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPX2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG68"/>
    <dbReference type="OrthoDB" id="3242303at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027329">
        <property type="entry name" value="TPX2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06886">
        <property type="entry name" value="TPX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPX2 C-terminal" evidence="6">
        <location>
            <begin position="717"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="413"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="658"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="733"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="792" mass="86601" checksum="65C8DBDBB90362D5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHD1</accession>
    <name>A0A9P6EHD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHD1"/>
    <dbReference type="OrthoDB" id="3543113at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="445" mass="49211" checksum="54506515A20C142E" modified="2023-09-13" version="1">MQTYAAKIWHLRLKPGKELIASHTLFRLLSLCNKDKSLFPALKTVIISMPSGFISQDTDFQSLNSVFLAITSPSLSALSITDITFSTEDFATSVLTAASVDCIEINQITLQGHLTIKSLEIIPQFLQLRNINLRLFNCVLPSAVLLQLGSALVHLKSINLSLDDSTFDTTTIPTTVVAPTNFNGLESMELKGSSVEIARFLGIVRPNQGTSPLQAIRLNFPSHWNTGGQEAVAVCIQECGRISPSSLRLLQMRGGRGLTLARGSLSPLAHCEKLETLDIRDVTVSLVDDDIQDICAAGRWNTLQTLRLPNSPDGQAPSLFSIRQLSDSCSNLHTLSISSDFRLCEYQVLQEAILDPFNDNNLQSLTILDVLTVERAVVMPNTMMLAIAVSRFLEHHFRRLVSMEYAGSRSNEWWTGVRTNMIQYRNIRAEMISITSQDQEGTTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI47</accession>
    <name>A0A9P6EI47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_893582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI47"/>
    <dbReference type="OrthoDB" id="3219854at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="3">
        <location>
            <begin position="43"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="361" mass="40839" checksum="0728C9A6A04FA430" modified="2023-09-13" version="1">MSAPLSNPTISNEDADREFKPWRCGDEFQYPPPKTGSDPDEHWKTVVNYLLQKERGRCEVWKDEVDKLLVFAGLFSAVVTGLLVDSYKSLSEDPIQALLAQLVAQGANQTVAVMSESGSSGRFSASESNKRVNALWFLSLVLSLATALLGIVAQQWLREQTRPSLQNTALRQLPGLLHMYSDAFDRFFVPQLFTTLPLLLIISVVLFLIGMVDFLWAMNHQVAIPMSIAVFFVFIFLLVTTVYPALQSPPNHIPTSRKSSMPRAPCPYKSPQSSAFYILVFYVRWGFATSFDVLHKFYTRSNTPLSPLSYLERYLQKSWLHHAGPWLTHRDLDILKFHRDEALENLCSKISPFELSTTTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI71</accession>
    <name>A0A9P6EI71_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 2 subunit gamma</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_765826</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI71"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000011">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000065">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044127">
        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="47"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="475" mass="51591" checksum="AF042E6F93419BDF" modified="2023-09-13" version="1">MSGDETLQKHDSDSESEEEELEETDIPSIDIDVTKLTPLSPEVISKQATINLGTIGHVAHGKSTVVKAISGVQTVRFKNELVRNITIKLGYANAKIYKCENEACPRPGCYRSYPSSKEESPPCERPGCGSKMKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLVAGNETCPQPQTSEHLAAVEIMKLENIIILQNKVDLIKETQALEHQKSISAFVKGTVAESSPIVPISAQLKYNIDAVNEYIVKNIPVPVRDFLSDPKLIVIRSFDVNKPGSEVDELKGGVAGGSILSGVLRIGQEVEIRPGIVTKDSQGRNKCKPIFSKIMSLNAENNHLQFAVPGGLIGVGTRIDPTLCRADRLVGQVLGAVGKLPKIYTELEISMFLLRRLLGVKTEDKKQTKVAKLAKNELLLINIGSTSTGGRVLSVRADLAKIQLTSPACTEVGEKVALSRRIEKHWRLVGWGSVQRGTVLEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIE9</accession>
    <name>A0A9P6EIE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_267444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIE9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="137" mass="15185" checksum="115B4D300B44581B" modified="2023-09-13" version="1">MSSCTRILLLQACVFSELCPSHSHFRHAIATSSLPTMTLYVGIYSKCTSFNFKHSIGDSSNALGEGRIRLVPPLRLTSGSVIEIRKIHRIFSVDITVDPSSIRNAKINRTVFCSGKLYLNITQFPLDAVFDPIVVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJD7</accession>
    <name>A0A9P6EJD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_187072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJD7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="51" mass="5748" checksum="4AB6E55F8B5EA43A" modified="2023-09-13" version="1">MADQQASSAHPVFFLTTCVFFGRILGFISCLTRFLSPIFKLSDWRRHSGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJG7</accession>
    <name>A0A9P6EJG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_142011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJG7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="11060" checksum="41CFFC717B99B977" modified="2023-09-13" version="1">MFDEFIFLISAMFPYALSLVCSTITVVLAREYLRMKVVRINEDLFRPHHQPFFFNQPRMLVCFGQPAESRSYATVYRHHLINATRSSGVSNSLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJQ4</accession>
    <name>A0A9P6EJQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_850735</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJQ4"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040500725" evidence="10">
        <location>
            <begin position="22"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="514" mass="58914" checksum="5B8643E007217A08" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKL0</accession>
    <name>A0A9P6EKL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKL0"/>
    <dbReference type="OrthoDB" id="3228793at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23422">
        <property type="entry name" value="beta-trefoil_Ricin_MPL_CNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="27250" checksum="8AFF0AF26697F73E" modified="2023-09-13" version="1">MSLLFDSSSYTDSISSSISETDTEMSTDTSDQEIAPGVYRIINDVNSGYVVDLSGYDLKSVIAYESHDGENQKWEIQRLGPGYSIKCLFNDAFLTLDSGLMDGGKLRAIPYPVSWEILPDAESTEGKIRYRIHWPESQYVLDAPDQGGHTIHLASQRPCKPSTLWRFQVISLHTAATSFSSPTPQLMRMPEPTEFMTKRAEPKPSFATTANTVIDAEDIKIDGDGEMTITTTTTTTVTTNVKVMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKR2</accession>
    <name>A0A9P6EKR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="3">7.2.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Cu(2+)-ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_850840</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="3"/>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKR2"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00943">
        <property type="entry name" value="CUATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0187">Copper transport</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="520"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="890"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="919"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="51"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="125"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00080126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9530394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1030" mass="109399" checksum="A97C63F190D9391F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL29</accession>
    <name>A0A9P6EL29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_762943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL29"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="4">
        <location>
            <begin position="65"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="313"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="573" mass="63923" checksum="2CD649C6FF022553" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPM7</accession>
    <name>A0A9P6EPM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BRO1-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_847049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palA/RIM20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPM7"/>
    <dbReference type="OrthoDB" id="64867at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF39">
        <property type="entry name" value="PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="3">
        <location>
            <begin position="3"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="738"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="806" mass="90967" checksum="73944A93A5B65C16" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPV2</accession>
    <name>A0A9P6EPV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_880518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPV2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="24173" checksum="E3EB5383E0968E54" modified="2023-09-13" version="1">MALHIGDSQLVQDGKTVVVLLVVGAVVTGHSSGAPVDFDVRGVVFIRIIADVEVECFQLGDPVIREGNIRTANRLNVENGGTYHNSCVVRRFYFAIDPVWVISRTALESTWSRGSHNVLSGTQPAKKRLIIATSSTNCLRAYTHRNITRVGTEYYCSETALISISYGSDSQSATSWIQANTVVKSVQQRFHCHVVDESCGEGQVAFLKDVVLGKRSNPFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ89</accession>
    <name>A0A9P6EQ89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable 26S proteasome regulatory subunit p27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ89"/>
    <dbReference type="OrthoDB" id="72325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000107">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040815">
        <property type="entry name" value="Nas2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18265">
        <property type="entry name" value="Nas2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nas2 N-terminal" evidence="6">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="122"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00068021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="209" mass="22882" checksum="BE636330EC6A749D" modified="2023-09-13" version="1">MGMTLPNPESPREQARALMARKDALELELEGQLSVLKSNNSDLHTPLVDREGFPKADIDIWAVRTARIRVIELRNDLKSIMDAIARALEGIYDPSLATSNIEEWESQSPSASSSSSKPFAKVEGVAPGSPAAEADMKQGDLVVKFDNLDQNSFTSSSLQPLADLVSQKENSSIMIRVLRSDSLVFLKLTPRKNWGGRGMLGCHIVPYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQJ9</accession>
    <name>A0A9P6EQJ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_832331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQJ9"/>
    <dbReference type="OrthoDB" id="3359674at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="551"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="744" mass="85082" checksum="F33A4ACE00FA0A82" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERL1</accession>
    <name>A0A9P6ERL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_471693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERL1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="327" mass="35180" checksum="651CE72D166835DB" modified="2023-09-13" version="1">MYTNMKMITRSCSTLPLTVSITTPPVDIETSNNATSSLEARRFPQDQFTISVASIVPGQNEDTPSAQGRETEGLPESERQSQSDDEIEVTSQQFGQGTGVAECSEDNSEPSSPSSTIEPAPVPAESGSATPVLQTPFTFSTKLDDEDLETGVALSTIHDEDIGIESLSDNGGFVGQTSTVHQLSSPPRVLDNLSDGDLGRLNSPVTQVQSSDRISEVDDQVKGKGTRSRASTTNSCASFPDSRETTFSFDILETVLDQLRDGGIRRPLRSTVAVLISANGEKYENAASEDINHYIEWALAEELISGGGEGDKAWITLRRDMNNDVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERW5</accession>
    <name>A0A9P6ERW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Indoleamine 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_805111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERW5"/>
    <dbReference type="OrthoDB" id="540174at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF5">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="438"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="54629" checksum="8E711CB1E7B59561" modified="2023-09-13" version="1">MNSLGDAHFLSLPRPDILVGVPAGVADTTTLAAHDFDVDTRTGFMPPQGPLSRLPNFWESWEKALDLAMSSGLQLGQKSGLTESDRTNSEAWRFTVRQLEILPIEDLIQSEIKLRRAHHVLAWIMHFYVHSLPPAEPIIIPAPISLPLLRVSRQLQLPPVLTYSDNVLYNWHLGGGKSDRLPTIHALRCQTLFTSTTDEDEFFLTSARMELVGVEALELMRSTMDEMFVGDDIAIRRITENLRALVPIIHRLRETLLQVKKGCKPQTFYHDIRPWFRGQDSQPGREWIFEGIEQDPTLVPPVELSGASAGQSALIHSLDIFLGIDKFSHRNDMTAKDIENAMAAEHRRAAFLERMQLYMPRHHRAFLNHLSSNRLRLREFVLSAVAGTLPEASSDDETSPKDKSALLEAYNMAVTALKELRDAHLIIVTLYIIGPARRGADPGSRATPDSKPTEETKAPLKGTGGTDLVRFLKGVRDQTKNALLPNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERX0</accession>
    <name>A0A9P6ERX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERX0"/>
    <dbReference type="OrthoDB" id="3204347at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="13139" checksum="F49813DE809AF858" modified="2023-09-13" version="1">MLAIMVLSSLAALLFVYVFMPALWASIMALDDSLDRHEAGIALVASRNPFRETGPPANMAKLILLRHKIQTNNRRRSRSNSQSRQGARTVNLTPSSPTNRSKATWIRLGRPFAGKQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERY4</accession>
    <name>A0A9P6ERY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_844825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERY4"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="273"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="41107" checksum="A5372CD31D349E12" modified="2023-09-13" version="1">MASRPTVNVRSSSGEASTSLPLPAVLTAPIRLDVVQQVHKSIAKNKRQAYSVSEKAGHQTSAESWGTGRAVARIPRVGGGGTHRSGQAAFGNMCRGGRMFAPTKTWRKWHVKVNQNQRRFAVVSALAASALPSLVLARGHRIEQIEEVPLVIEDAAEAFTKTKQAVTLLKSLNAYADVIKVSNSRKLRAGKGKLRNRRHRQRRGPLVVYNEDAGIVKAFRNLPGVELVNVRRLNLLQLAPGGHLGRFVIWTHGAFALLDEVFGTFEKASIYKKDYFLPTAKIANPDVTRLINSDEIQSVVRPAGQKVQKRPWTQKKNPLINKAVLFRLNPYAKTIRRQELLKQERLKKKAAPKKRQPKAASKAFIEGLLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESF0</accession>
    <name>A0A9P6ESF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STB6-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="19806at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059025">
        <property type="entry name" value="STB6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25995">
        <property type="entry name" value="STB6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STB6-like N-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="765"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="843"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="905"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1434" mass="153827" checksum="79565692FC8C79DF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESI3</accession>
    <name>A0A9P6ESI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_873443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESI3"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="32186" checksum="7B73B0CC98FA9F41" modified="2023-09-13" version="1">MSSREISPATLSIAYSLLLLILTIIGFAHPALRSRFHNTFEAIHRFLGWTAIILFTNDHPAPKIPLSKCLQKSTEFWLVVVLTASIALPWLRLRRCSVQAEVLSKHALLLLFDYGMGMNFNACLRFIRISDQPLFEWHAFATIYIPGIKGYTAVVSNAGDWTQKICVRGIPTLGVLRIVPMFRRLVIVATGSGIGPVAPHLLARQTPIKLVWTSPSVRETFGDQFAAPDALVHNTRMHGKPDMIQLAHHSYQEYVAEAVIVTSSPKLTSKLIYGLSSREIPAFAPIFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESL0</accession>
    <name>A0A9P6ESL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_748294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESL0"/>
    <dbReference type="OrthoDB" id="2417614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053006">
        <property type="entry name" value="Meiosis_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="1">
        <location>
            <begin position="88"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="29162" checksum="B0CB31EF9689A4AB" modified="2023-09-13" version="1" fragment="single">IQCRGITRKGRKCKKSVKNFGLDGRVVYCKYHGRQKVRPELEGASILLFNHTRSECFAEWIPKYLRGETRKRLQQEMIKPSSRSDSPGYIYVLELAPDDTNFVKFKVGRSNDVGRRLREWRRQCPSTIPVLKGFFPGDLSEDGFSSMAKLTMPGPSGPLCHRLERLIHIELTDLVSNPAYLDQSWPQVDRPRVLDVVNSQRASAPCLDCGHCHQEIFRLRRWRNDKREGMEWNLIIIPLLERWGKYVEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESU0</accession>
    <name>A0A9P6ESU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_755761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESU0"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005373">
        <property type="entry name" value="PHAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039156">
        <property type="entry name" value="PHAF1/BROMI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465:SF2">
        <property type="entry name" value="PHAGOSOME ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465">
        <property type="entry name" value="UPF0183 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03676">
        <property type="entry name" value="PHAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="43363" checksum="69A0F8E54272B901" modified="2023-09-13" version="1">MYSALDIDIKPGQGFGIFEIGTSLWTLLDILRREPNLYPQIDVKYDPDTSATTPVIVHIRPHIDLLFSGKQQRLHTVCIRQLRDQSPPLTVQYNGNILSSPNEVLRRVGVSKMFGPTYPGDELRYPGIWFSFEEDGIGEGLTAPRPGDKAQEVKRIIILQNERDGSNSAIDALDEVHECAAMTGELARAIVKVHDGVTLQFHPIAFSTFLHVGIGETTAQDLQLELGPPPRIHYKEDERMKIHAAVRPTDSEDGTGYFYNYFQHGIDFLLSERTHTVRKIILHTNIPGSPLFQRYKRCSWEIEDKPEDDEDDTPPRKRFFDRFETISHFLGHREPPPSMILDRTDEDEHLTLPNSKTRLHGYDGIVLEVSELSQVVSLVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET11</accession>
    <name>A0A9P6ET11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 79 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_842806</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET11"/>
    <dbReference type="OrthoDB" id="2796951at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040234746" evidence="2">
        <location>
            <begin position="17"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="3">
        <location>
            <begin position="407"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="577" mass="61593" checksum="9DFAE1ED0DE0F22C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETB6</accession>
    <name>A0A9P6ETB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_878985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETB6"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="782"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="881"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="934"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="973"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1151" mass="122725" checksum="33B91071BF4173EA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETC4</accession>
    <name>A0A9P6ETC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuole protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_729861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETC4"/>
    <dbReference type="OrthoDB" id="2128042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031606">
        <property type="entry name" value="Kch1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424:SF1">
        <property type="entry name" value="LOW AFFINITY K(+) TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16944">
        <property type="entry name" value="KCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="52647" checksum="B4802DF5F7CA5A59" modified="2023-09-13" version="1" fragment="single">MCGGGAKWKREVVPDHKFDFINTREFNDTGFMMRMKYLWLYIIVLKSFLVYVSDIFSAITMLTTKNWSNEIILQCSQMNGCFYIQFETGKWLFVSCILVGFLLLAYEGRKARKIIQSRDISYAFTNVMANNYYSLRSYDHFCFFDHISNSTKTIDDFAFFVFFTFKSWKRLLLADAPRQAINGVTLYAIYTVKRSQAKLLDNPPSMWDIGQYFAGNSASTSALTISTLFTVLVCAGSLIVLVVAGICYIPLLLHIQGNLKEYCCHKVDKRIGDIMKRKLKERRAEAMKVAQKEARGDYSHLKNKKGELVAQPLPQPTLPNLSVDDDDDAASVVTRGPPPSAYSQDQYYHNEKMDYPPMPAYNPYSNHPNPGAPQFNPSMTGFDDLGGPPQHGYGYDDNESTANLTSSAAPFARDPIDRYNSPYSAGTPASSAHGTYDSADVYQGRAAYTPAPQQHQQQYDYFPQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETG3</accession>
    <name>A0A9P6ETG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">4'-phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_780754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETG3"/>
    <dbReference type="OrthoDB" id="15433at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="8">
        <location>
            <begin position="5"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="134" mass="15133" checksum="A0AE3248C952D59E" modified="2023-09-13" version="1">MTILGLGVDIVHLPRIAALISRRSADRFACRVLSPTEYGQWKQITRSAAPAEQIRFLGVRWCVKEASYKALYPLVKPTWKELTYHPLSNGQKPWLQFHPNNANNFEKVGQVHVSISHDGDYIYSSVLIEAPAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETW3</accession>
    <name>A0A9P6ETW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_235807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETW3"/>
    <dbReference type="OrthoDB" id="3060478at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="13548" checksum="41B8414E31B3CF5F" modified="2023-09-13" version="1">MQSAAKNQDLADELVPLLVKELKSAKEKIKDLERELVNMRLRPEAESGHSNQVQDYKQRTEAAEHAMEVLQKNFEKSSKENDKLRSVIEGIKEIKVKVKQVIFDSVAYTPFLSDIFIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU53</accession>
    <name>A0A9P6EU53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_888926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU53"/>
    <dbReference type="OrthoDB" id="3352776at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16794" checksum="5237EB39183A0D56" modified="2023-09-13" version="1">MSPTRKDLFNAAENFCQAFAEHKDLEYILSLFSVTHATSVIEYGDPILAPFLGKEFIRPRKIQEYFELLASLVSHENVKFSEYFADVEAMKVSVKGDGKFTWLSTKQSWHETFTYTLDFDDELKVVKYQVWADSGAAYLARIDNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU68</accession>
    <name>A0A9P6EU68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_843138</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU68"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000071">
        <property type="entry name" value="Dihydroorotase, homodimeric type, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="74"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="38759" checksum="3A229CCA2205DCE7" modified="2023-09-13" version="1">MTLQISSPADFHVHLRQGTITDLIVPHVRKGGFDLAYVMPNLKPPITSTDQALEYQERLLKIDSNVDYLMTLYLSPELTPDEIRKASKAGIVGVKSYPRGVTTNSDGGIESYETYYPIFQVMQEVDMVLNLHGEVPSDPSANIHVLNAEPSFLPHLFKIHEAFPKLRIVLEHATTRAAVDAVKKCGPTVACTITAHHLELIVDDWAGQSWNFCKPVAKYPDDRKALQEVVREGHPRFFLGSDSAPHPPDTKSTSSPSHACAAGIYTSPILLPLVAHLLESFGALDKLEDFVSTNGRSFYRRPIETHVNGRTIQLHKTQNLVKGKYEFENEALVPFWAGKQLNWEIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUL2</accession>
    <name>A0A9P6EUL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_781231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUL2"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="92"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="366" mass="39904" checksum="1138FEE421423C89" modified="2023-09-13" version="1">MASQNTKEDDEIPVPERPPSPPLHTTFAARGIHPPNFSAFKPRDYRIPSPHAMTHVAWSCDGKKLAAVGIDKGTRVWTPEKSMESRAATVFTGGHTDDVDYVAWNPTHPELFCTSSQKDRRIVFWDARQTRYIQQVPLKVSPVQVTYAPDGNSLLYVSGGNQLFFMTRGKASEPREEGKPPTGPAKEKEEWRLADAGSPRPGSTAIFNHMGDGVIVTHHQEHTLRVMDYPSLTVREAPAAHVGGCVAVALDPRGRYLASGGYDSIVNMFDLNDWICARTITSCEHSINSLSFSHDGEYLAIANAGSYIDICATETGVPLHRVPALGPSPTVTWHPSRYVIAYCGQTKAREGGPAAVAVVSLFGLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUQ2</accession>
    <name>A0A9P6EUQ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Stress-associated endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_30422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUQ2"/>
    <dbReference type="OrthoDB" id="16679at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="65" mass="7285" checksum="DAF8F39DBADCD25B" modified="2023-09-13" version="1">MPTEFEMRQRNAKFAKDVRAGKKATHPSRADKLANRSALSLWALGLVVFVVVGGVLFELIRIIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV52</accession>
    <name>A0A9P6EV52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_878731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV52"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="17928" checksum="541C0FCEDFEABED5" modified="2023-09-13" version="1">MTDVTTPSEVPEAPNGVLHDSSSPENIVEATVNPHDVQEEGDADGEGEGGDEEEFEEERHVIIDDEDDQDDYDEDEEDDEADAEAPAPTSTLTHLLLGNPSAGGDDEENDDDDDEGDDDDYAPAPVTPVEPVPAVAPGPISRKRSRQDAADEDDDDTEEQTGKKIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVE9</accession>
    <name>A0A9P6EVE9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVE9"/>
    <dbReference type="OrthoDB" id="2127032at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000030">
        <property type="entry name" value="NAD binding Rossmann fold oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF6">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="53"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="419" mass="46530" checksum="E2D1ABF8C1103E5F" modified="2023-09-13" version="1">MASEQTINALMCGTGEYTTGWTGSGASQSDKKIGVVALTLFDLRRRGKVDHLAMVGVNGKKFPAIREHLQTNIAGAYKDMDVSFDEFPKNNLVDAESYKQAIDKMKPGEAVIIFTPDTTHYPIAVYAIERGLHVLVTKPATKLLSHHNDLIALAKKHKVCCWVEHHKRFDPVYSDAKARAATLGEFNFFNAWMSQPKSQLTTFKDWAGKESDISYYLSSHHIDVCCWILQDTAVPTRVVASAATGIATSEPYNCVPQTEDTITLLVDWQSTKSQTHKGTAVYTASWTAPLKAGVHSAQHWYYMAEKGEISVDQAHRGYDVTLDETGKAWYNPFYMKYSPSESGHFDGQRGYGYISIEKFIDAARSVNAGLTTADEYDKNGFPTIANTVLTTAILHAGRISLDEKRPVGIKKEGDLWVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI38</accession>
    <name>A0A9P6JI38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_172646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157984">
        <property type="protein sequence ID" value="KAF9521838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI38"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="8964" checksum="51A3AB2C77A225DE" modified="2023-09-13" version="1">MSLRLGASMIVNFPEAFIHLPKTFRVVLRHMFKGQKSFLNESEKGRKKIEALGTSTIYVFVLICCFFRGSTDRFTLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIA1</accession>
    <name>A0A9P6JIA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_140613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157960">
        <property type="protein sequence ID" value="KAF9522122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIA1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="16068" checksum="7EE8A2CB6CB1ADDD" modified="2023-09-13" version="1">MFPDTGPHPASVVFRAVDCYNGHSSFRSNARRQSRQDIPVTLVLSPAPTVSFDPNRRNRLAVNLLAFEQVYIKLEVFGEIEDVLVGEVAILRILDSTHNEGTRAMEDYQATVFQFEKCVLVLKTNKQTQRWRKMRFRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIC5</accession>
    <name>A0A9P6JIC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_865104</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157970">
        <property type="protein sequence ID" value="KAF9521960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIC5"/>
    <dbReference type="OrthoDB" id="19448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040246358" evidence="7">
        <location>
            <begin position="20"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="141"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9521960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="414" mass="42893" checksum="29E535B1CC0C6FC9" modified="2023-09-13" version="1">MRFFAAPLTLSLLTASALAAVTPLIPIQKSQGDTSGRHIVTLKNGVSQDTVLNALKITADSLAYKWSIINGFAGSFDSNTLNALRSNPNVESITEDGIMKIVGQQMDATWGLGRTSSLQKLTDQDPSHLTFDYIYSDETLGSGVDIYIVDTGVRITHNTFGGKGGRATWGASFDKDISLPVDFTTPLDVPPPTIHVPDVLMQDDNGHGTHCAGIAAGNQYGVAKKANIIAVKVLTGAGTGSTSNIISGLNWVKDNVKKTGRPSVISMSLGGGGNEALDNAVTALTGDGIHVTVAAGNDNTDAKDTSPARTPSAVTVGASTISDTAASFSNYGSIVDIYAPGQDVISSYNTDDNASKSLSGTSMATPHVAGLIAYFAATDNLAPAAMEAKLKNMCLKDKLSAVPSGTINCLAHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIQ9</accession>
    <name>A0A9P6JIQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_864388</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157943">
        <property type="protein sequence ID" value="KAF9522512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIQ9"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="57911" checksum="96BD6E774F1F9767" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIS1</accession>
    <name>A0A9P6JIS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIS1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="53" mass="5833" checksum="55DC21E7F0C3799B" modified="2023-09-13" version="1">MPYDKPTSMLPPHLRALNQPPIFQCQGALHGNPSGRLPISYHSHLGSTNLLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ33</accession>
    <name>A0A9P6JJ33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_864060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ33"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="206"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="541" mass="61495" checksum="E5D580AD8EBD397C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJQ5</accession>
    <name>A0A9P6JJQ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_863528</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJQ5"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000047">
        <property type="entry name" value="Small nuclear ribonucleoprotein SmB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="129"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9523054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="19115" checksum="AF3A7A080642729B" modified="2023-09-13" version="1">MPPPKSKGGKMLNLINWRLKITINDGRAFIGQMLAFDRHMNLVLAECEEFRRVRPKKKAGEETAPEQEMKRALGLVILRGETVVSISVEGPPPVVDEDKKNALPMGPGRGMPAGRGMGMMPPMGQPSLARPPMPFPPPGMAGPPPGFRPPGFPPGMPFPPGPPPPGFGGPPPGFQPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJY3</accession>
    <name>A0A9P6JJY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_862335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJY3"/>
    <dbReference type="OrthoDB" id="3222645at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="699" mass="76674" checksum="D5C6564365914ECE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK38</accession>
    <name>A0A9P6JK38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK38"/>
    <dbReference type="OrthoDB" id="3039255at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="58055" checksum="555D1C8831126F5A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKQ5</accession>
    <name>A0A9P6JKQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_609433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKQ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="53" mass="5945" checksum="E66C488CB30C6AD1" modified="2023-09-13" version="1">MDFGVLAGLKGYGIMSKTLENQRFRGEPREPKTLDARKVVYLPGCPAGHRRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKQ7</accession>
    <name>A0A9P6JKQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_886587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKQ7"/>
    <dbReference type="OrthoDB" id="5289249at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="36"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="24424" checksum="F289CACE5CE6E7E9" modified="2023-09-13" version="1">MYQQTTMQDGSPSSNQTSTATSQKTSSLPSGIRPSNFIKISRIGDEIVGTFVIDRDMKIPDRASGYHLHLNSGSGAGSIDADVFSAPPSGSVTAQEKKVRTMIYLVGGKITINLHRSATDEEGYPLYMNISGTQNSASILSLPRSFKGPVHLGFKGNHLTFSPDLLANFTLFIEENGVTEGFIGDFDYTQWKVIGQWLGDTLYWTPLNKISSTLTLRYDDEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL92</accession>
    <name>A0A9P6JL92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_738245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL92"/>
    <dbReference type="OrthoDB" id="8964853at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328:SF3">
        <property type="entry name" value="PROTEIN MAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328">
        <property type="entry name" value="PROTEIN MAX MYC-ASSOCIATED FACTOR X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="18"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9524479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="7414" checksum="E0FD470EF6C3189E" modified="2023-09-13" version="1" fragment="single">SSNNAPKRKPSRRANTAERRATHNAVERQRRETLNGRFLDLAALLPNLSQIREGFGMVLSGELEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLC7</accession>
    <name>A0A9P6JLC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_885719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLC7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="29381" checksum="06E97A1E9702A76C" modified="2023-09-13" version="1">MSRQLRHFCAEIETRGESIETVKTTTAKGRLVLHERLQSIRTLPGFCIYKSSPALQHYSSDFRVEHVQRFGHADSRGSPGYVLMWVFKKRSMPDGDDLMDEKPVLKREGGARERRNARRCWIRAADALSSVLEAEVVVVFSGTTMGGEPTAKTGRDFGMTETVKSGQIIPQRPDGEERQRQVEEENIKRDSGLSGCRSGLSRGKPNTAKTSSSFPNLPRSLESPPPFFYGRQVWPLLKTPINKLSNTIALRPIILATWSYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLN3</accession>
    <name>A0A9P6JLN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_572440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLN3"/>
    <dbReference type="OrthoDB" id="25921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="699"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="774" mass="86009" checksum="E8175CC804E6C82B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM94</accession>
    <name>A0A9P6JM94_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_512942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM94"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="30139" checksum="1EB356593CDE12BA" modified="2023-09-13" version="1">MSLPTEILNHILSFLRRDVKSLKACARASPLLVPLAERHLYAQIVLLPRLSGDVFSDHDLYFNLSQLAKLIRTRPHVAPCIESIRVMITYQDLMAWLYPPISGFADHGSPPHLPSLKVFAVTLRGLRFKPIRWNLFPETLRAYLENMIHLPTIEEITIQGVLGFPLKILNGCWKLGSLELDGGGCILDPKAIQLSSPPEGIISHPPRVRLRHLYLQRGDGPIDEIVSWLKPERPHLAVGTPESNLEHLLLHFGGAYSGYWQEHEINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMV9</accession>
    <name>A0A9P6JMV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_769798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMV9"/>
    <dbReference type="OrthoDB" id="1060854at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="28256" checksum="DD25B36444788883" modified="2023-09-13" version="1" fragment="single">MLAVVQPYSTASPDVPHRQRSSRTLTHNNLASSQPPSLPTAPSKIPTTTTTTTTATPDADTPFDIISYPPSDLLKLLANILTHIATTNDHLSPSASSSSSSPSHYQSHQPPDPLSAPPIWHSLTTAARNAISTPAATLTFHARNIPTISLEAYLLRILKYCPTSNHVFLSLLVYFDRLSKLGQEAVGRSFVIDSYNIHRLVIAGITVASKFFSDVFYTNSRYAKVGGLPLHELNQLELQFLLLNDFRLVVSSADMQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNE0</accession>
    <name>A0A9P6JNE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_938112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNE0"/>
    <dbReference type="OrthoDB" id="3270336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="654" mass="73417" checksum="53320E106E6D4E56" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNN9</accession>
    <name>A0A9P6JNN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aegerolysin type hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_769707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aegerolysin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNN9"/>
    <dbReference type="OrthoDB" id="2727348at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019836">
        <property type="term" value="P:symbiont-mediated hemolysis of host erythrocyte"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009413">
        <property type="entry name" value="Aegerolysin-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06355">
        <property type="entry name" value="Aegerolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007951">
        <property type="entry name" value="Hemolysin, aegerolysin type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="146" mass="15940" checksum="A6C0534BDAA0B4B6" modified="2023-09-13" version="1">MSQPDIETTAYAQWVTIDNGNNSPGTATLVIRKVSLSWGKFYEGGNKDREIHISSLEGKEIPAGGSFKIYSCGRENASSGTEGSYNLVEKNGGRLVRRVYWNCPLGTKTNTFTLSGANRDWVIQQDGGNLDSGALGDIKLTMVKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP20</accession>
    <name>A0A9P6JP20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isoprenoid synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_768859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP20"/>
    <dbReference type="OrthoDB" id="2861623at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="364" mass="41124" checksum="CBC17824CCFB68BE" modified="2023-09-13" version="1">MSLQPPHKPQSFQLPDLFSAISTLELRTNKHCTFATQGIERWTEENDVLTEVELRGLSVKKIGLLAALCFPTCDGPQLRQLAKAATVLIYSNTRTFSDPVETESLWRTADDLELDGFELLNLHPLLRQLRLSSTSHGFLASQSWKDRFSDSVKRHFNAREQTSARSSIPTLNEYSELRKDLYGENIIFLLAELHEAFIFPKDDEDRRTRLITLKELAFEVIALSLDVLAYQQMEKNERSRPFNIITVLMQHQGLSLQGAVNVAGNKIRSAFTSFTAAEASIFQDSPQSKPSSLTSTLLEWLGRSSTIPVANDFVQENSENDAIKRYIQALKDCIVGSLNWAYETEMFFGGKGAEVRSFGWVFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPG2</accession>
    <name>A0A9P6JPG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_875940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPG2"/>
    <dbReference type="OrthoDB" id="2894188at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="20237" checksum="893103AD53EE9799" modified="2023-09-13" version="1">MAEETKLNPFPSGVLTAEHEAQIEKIRSVFKRWLPAAEDSRKKVDGAKEQLQSVTEDLKNLQIDAPYAYSPAPPYIFRPILLSCTKTYWLAVIAALSDDQKKEMAQRLNCIPPYGKRVPQFDGKRCVEQASELNDREYEGIMRCAMFALINLLPSEVVRFWRELSEVGVQTWEERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPI8</accession>
    <name>A0A9P6JPI8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_367510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPI8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="39755" checksum="6365DA3915099351" modified="2023-09-13" version="1">MPPKFSPLPYSLFPPIMDHDLPRELWDCITIDLADADVWKLRGVNRILRQLALDRYFKSRAICLRVGHLSKLDHLQALSWLETPEVASRVRKLCFAAGDWRPRSYRVEGLPRSTSLKNAKTTLNAVLGLYDRFRWRHLSTTAHRLLSSFKNIDEIFVETNITTISFAIGPTEAMVELLRSLQSLSSFPNLQRLSFEFRGPDALFPAGRYQNILLDYLPPFLNSHSTTLDLLCLSVDDFLGLNFQFDLAFLSRLKRMPKLQTLRIYLPISLPSASAQLRRFLEEHAATLQHLTLQVQLPQLPIQGSVPLMSLYTPLPHLRHLDIRKLAPPDRPYGLLPNFMDTISSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPP3</accession>
    <name>A0A9P6JPP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_364703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPP3"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF85">
        <property type="entry name" value="A, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040122986" description="CBM1 domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="303"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="339" mass="36692" checksum="C96FCDA7CDAE6736" modified="2023-09-13" version="1">MRLSGLLAIANILRVASATAGPNWTGYSGLRYFFVYGDSYTTVGYNSKSPNPTDKNPIGVNYPGQTTSGGANWVDYTTITYNQSKLLTFDYAISGNTISGVQAQINDWLPTAGKKPTYAPWSAKDSLFATWIGINDLNANAQPAPSMTSLFGLMDTLYTNGARNFLFLNVPPFHRAPFAGNNAQLGTRIQAWNTALVSAAAAFQTKHSDISTFVYDSWTLFSKLLDNPSQYGFTDVTTTGGSFWQDVIHPKAKVHDYMAQDLVAFLKSQTPSSSPPTTTPTGDPGTPTPTPTPEPTPTQPPQPFQTHYGQCGGQGYSGPTSCESPYTCKVSSQWYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRC6</accession>
    <name>A0A9P6JRC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_875555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRC6"/>
    <dbReference type="OrthoDB" id="2596908at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040116064" evidence="3">
        <location>
            <begin position="30"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="339" mass="32828" checksum="D63312826DCEE769" modified="2023-09-13" version="1">MFSYIRLDSVAFLAFFLQSLLLLSSSANALPILARQVNGQPKSVTTVHTTMTPSGPVTETCVLVFNPVKDAQGKDAVEEVKTCTVTSGDVGSSSSSQASSSSSSSTSASTATPSSSSSSAAAVTTSAASTSSVVSTAATSAVTSVVSSAQTSAASPTSSAAGTTAAPATSTPVAATSTGNGDITVIGTRSVSSSVAAPSAAVTSSSSAAAAATTTSSGPSASSAPVPVVVNGMSTVPGSPVTTAVPDNVPTPSAAAASGTAAAAETTPTQAAALALPGKTLSVLPIGLGVFAGISVIALIVVGLVTYERTKFRKARCYKFRQQRLAEQASAIGYGGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRD2</accession>
    <name>A0A9P6JRD2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRD2"/>
    <dbReference type="OrthoDB" id="3117669at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="37390" checksum="F44ABA0817E8818E" modified="2023-09-13" version="1">MLTQPVFPQEIFSLIFSIISHPLELKDNGVEVQSTICSLSKRTRAMVKRGFAFDLRSVEDLDSLWTTVDAFSRVFYDQPFTFGDTKIIQVFIPTTGNDIQKVKDLFTHLRGVKEVNFTFYRKTEWTSRFFSVIITWAPFLQALEIMRFKYKIFNFDLESKGVASGWLSPNGWTNCICHFPTIRVIVIDTPQLAFLAQEDEDGEYDITTEAEKQWISTWSSGLSQLQRIYLNHAYDDELGVTSWDFLGSRNVFSRMEDGTFRSFPWRPALQEFAFAPAIHKPPVHDGRHRRVKKEDLDFYDSEEGDDCRIAGEDKDQYVDMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRS7</accession>
    <name>A0A9P6JRS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRS7"/>
    <dbReference type="OrthoDB" id="3251367at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="689"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="892"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="923" mass="99885" checksum="2B4A44E3BE201587" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS07</accession>
    <name>A0A9P6JS07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_868785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS07"/>
    <dbReference type="OrthoDB" id="3251057at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="40775" checksum="055BCB39AFB794AC" modified="2023-09-13" version="1">MDKFAEELAKFINPFDDMDAQLCCFAHSINLIAKIFISFFFVTRRQKLIESDDESENEVEVKEEEVDDDDESVDGLENEVVDEEDDETTEAEQDDADEGQGRFNEKVTKKLREKAIAEMRTQGYKLKSAEIKSTGELFPKIAGLARRVNDSGTLKEKFDRLVTKSEDITGSRTALSRQVPTCWNSEMECLVSYMHFKDVVEQLLAVSSLKLGRYKLSSEQWSMTDDVSQVLMLFEDITQIFSQAEVPLIVDVLPSLYDLRGGLEAARDDSEHEVADIVRVACHASILVANKYLNLIEDNDFYLFTIVMCPDRKLRWFKDHGRTIQQVNQLKSRVIASWEKSYKQMGREDDDFFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSS6</accession>
    <name>A0A9P6JSS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_867610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSS6"/>
    <dbReference type="OrthoDB" id="2417614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053006">
        <property type="entry name" value="Meiosis_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="2">
        <location>
            <begin position="244"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="412" mass="45167" checksum="07A4ADB9127842F0" modified="2023-09-13" version="1">MSMGESAGYYQQAPLPIPPQQNQAAFIGGFHPAIPSYDAPSASAPNLPPKPPSFMPAAFSESGEPQSLTMQYALQPPDTPHRPHSNPEPPTSSSHKPHKPTASAASTPGRPTGGKTKPPVTPNKASKSDSGSSSGSPSKPGQEQCGGVTKAGKRCTRMVKSRPATVSADSDDDDPTPVFCYQHSKELMGPSGYYSRKNGEWIKFEGSKTYILRKEWIPAYLQPDTQASLRVEMEKPKSGSDVPGYIYTFEIREDRQGDTIKLKVGRAVNLVKRIDEWGKQCGSKEQVLRGFYPGSVEAEEASLMKGRVVAGEKSPLCHRLERLIHLELGDLISSSVYLDPSWPNTEASSSPGPEDKSKGSSDGRKPCPDCGCRHKEIFEFTRWTRGKYKGKEWEQLVKPVVERWGKFVELYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTK6</accession>
    <name>A0A9P6JTK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_867382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTK6"/>
    <dbReference type="OrthoDB" id="3271227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="137" mass="15516" checksum="59D06FF3CDAEDD27" modified="2023-09-13" version="1">MTELIRRASSKPCSPFPAPVSTPSLKDKSKSKSTRTDPDPIGSPAPLHSTYSPYLKSSRRLLSRIAPLHPNRKTPPPPPPPPPPRKKTKKELEMEEKWEEELVEEVGGIEVFAAMEESGRKELRRVKREREMCGYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU18</accession>
    <name>A0A9P6JU18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">OPT oligopeptide transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_848314</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU18"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF3">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="668"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="713" mass="76511" checksum="13182500372C4C90" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUI0</accession>
    <name>A0A9P6JUI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Kinesin heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_846753</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUI0"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000031">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="12">
        <location>
            <begin position="5"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="385"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="935"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="472"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="645"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="710"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="797"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="92"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9532998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="978" mass="108544" checksum="134B53156D4EE387" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUM5</accession>
    <name>A0A9P6JUM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coiled-coil domain-containing protein 55-domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_846782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUM5"/>
    <dbReference type="OrthoDB" id="446635at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053246">
        <property type="entry name" value="NS_splicing_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845:SF1">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="4">
        <location>
            <begin position="55"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="42003" checksum="5EF62C2152F4940E" modified="2023-09-13" version="1">MKLSISLNKPKAAQTKQPPLKPSAFGSAEEDVEENVEQTKTGSLALAAQTSKAMRKRIDAEKQVDASVFEYDEVWDKMQETKQRQKVAKEVDATAKKPKYIQGLLATASTRKLDHLRAEEKMMQREREAEGDMYADKESFVTQAYKDQMEEVRKAEEEEKKRDEARKKQGGTSIGLTHFYQKMLEENAMKHEETVAATEKRVIGPQAGPNLTINKPASMAPMGDSELAKLARAEGKEVELNDDGQIVDRVELLSAGLNLSLPNTRNLGKLTASTLKDGQDDQPIQTHRAVGTAASRREINERRAREIQQQLADEERRIEQQKMSEEERATQRAVAKRNNETSVEDARARFLERKRRKLEEAQQQPQDPAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUX7</accession>
    <name>A0A9P6JUX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_471554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUX7"/>
    <dbReference type="OrthoDB" id="549353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905762">
        <property type="term" value="F:CCR4-NOT complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10910">
        <property type="entry name" value="PIN_limkain_b1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024768">
        <property type="entry name" value="Marf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379">
        <property type="entry name" value="LIMKAIN B LKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379:SF3">
        <property type="entry name" value="MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="7"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="487" mass="53546" checksum="4CF4779A8BAAD2E4" modified="2023-09-13" version="1">MKNIEDVAIFWDYENCNAPANASGYLLASNIAALARPYGTIKQFRAYLEITEQSASSRSTTLRSELQSSGVSLVDCPHNGRKEVADKMLLVDMLAYAIDNPAPATMVIISGDRDFAYALATLKLRRYRLVLITLPHAHASLRCQASVCLDWFSDVVTPANTMSTLPCLSSLPSHRHQQRRSSEYAVPKRASPPLDTSRHASDTKLSQKGSTPDVDINQYLSYRKERWDAEISQWDVEQIGLGRKEEVLKPSTQEGNLNTAGLRKQTSSVDSFQRPTTLYTRKSEENPSSIIKRNYQTLENNQPPFFRVDPLDDEVFLSSSYSLPSTPEGLGSSILSPHSTTVGSAPIGSFNDRIRSTHSNIAPTSQPLPPVQTSLGSPMNLSFMPSTNLTGRTKLEQQDTSETSASLTSSTNPIFDALIDVLRAHRLKGRSNPLRSAIGLELAKRGNVYGKAGAANFKDYVTLAEKEGLVVLGGRDGYAWITLLDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV13</accession>
    <name>A0A9P6JV13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_728072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV13"/>
    <dbReference type="OrthoDB" id="3005441at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="61" mass="6486" checksum="A5452CED092A09F7" modified="2023-09-13" version="1" fragment="single">PALAERAAEGCWYDSQIGCTGGYCWKVCGNNGEWCWTANNGGVGSLISCSNWQDCSFSAPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV17</accession>
    <name>A0A9P6JV17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_222394</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV17"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040542743" description="Hydrophobin" evidence="6">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="11606" checksum="BE1F8E26DF1B5849" modified="2023-09-13" version="1">MMFTKAFALLALPFLAAATPLEKRGGGPTCNSGSVSCCNQYHASNSPTAQHFGGLLGITGQAMNDFSVAVQCNPVTGIGLSQSGCKQRTLCCDGNNISNTLFNFQCIPITVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV84</accession>
    <name>A0A9P6JV84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV84"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="514" mass="56477" checksum="ADF805DA15A92F47" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVP6</accession>
    <name>A0A9P6JVP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptide-O-fucosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_842145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVP6"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9535682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="450" mass="51818" checksum="2888924D915720A4" modified="2023-09-13" version="1">MIPRTRSFYTICISLVGLSVLGILSSSLWTLRPSNHRLIQEEQSVVQHPLEGDDLFGPQYVLRGPPTQRFRDNLRPDVQYVSSWISAGWTNDVMTYINLIYLAVLTNRVPIVGMFVPTHVGGSTPTVDFGEVFDVPRLRKTLGRPIVEWHEVKDRNSTVSEDIGCWSVWQAVQNREEAPRSSVVPGYLKLDISYTKAPTWINVIPGYEHDQHSSFSSLATLGFPDIRKDHLVEPRESPTHMKLPPDEQILCYDYLYYVCSNQPFEFDFDYSPAWLFVGQHMHWAPKLQALADDYIRATFQINDPSVQTPPYIGIHIRHGDFSNYCGDIPLEDCFAPISVIARRVEEVKKELMQKKGIAVEHVIMTSDERKEEWWEQVRQQGWYQVDHSQTVERYGRWYPVFIDAVIQSDGIGFVGTDRSTMSMLARRRVLSWRGGAVRVFRWGRPGADDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWD6</accession>
    <name>A0A9P6JWD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWD6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8621" checksum="BD56FA954568032B" modified="2023-09-13" version="1">MLTHEYGLLQTTLRPKILLHSWLSFLPSLTFTQRISNDSSSLSTGRRFLFFVTRLSHESYACREFMTLQGKIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWI9</accession>
    <name>A0A9P6JWI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_203332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWI9"/>
    <dbReference type="OrthoDB" id="3130847at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="353" mass="39024" checksum="35E7B4D1691F2C52" modified="2023-09-13" version="1">MDSNIPALEITRLELPFEVWGLVVDELASSNAISPLKALGVTCHALQLPCQKIIFAKVSVFVRSTEWAGPEADLRNRQLLDILIRSPRVANCIGHLNIRVGGQRCLTDSDAVPQIIFKLPSVTCLHLDISRTDWAIMKKTPMASSAIDYLFSLPTLNELLLRKVVEMPVKKLSKIPNLKCLILDSATIDIGNSAIISGLKRPIPLCEIRAIGTGVASYPILNPNLKLTSGSQALTISSFRTLDITGELNEATRKTLLGAGAPLKEVSLSLHRDLLFAEGIKPVAGTLKVLRIAVYEDFETLLPKLCEELKLLPLVLGQNLIEQLYLKFQFRKKLRIKYQQQLGRTCKLAWSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2V2</accession>
    <name>A0A9P6E2V2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158042">
        <property type="protein sequence ID" value="KAF9521500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2V2"/>
    <dbReference type="OrthoDB" id="3235041at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040267502" evidence="1">
        <location>
            <begin position="29"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="330" mass="37165" checksum="CF8998895FBA77FF" modified="2023-09-13" version="1">MSCCHHSLPLTQNKILFLLLLGCQVVKQWFHNNGRRSSAWRGLSAPRKPPVTQVLYSLYREAVKAKVKELSGGAAAGTSLWLAQFQPACQQVLDSLSPAEFDAVEAARTEWVVKVYPMEEQLRMLCKHGKKHLCNFADQVFWIFGMRICVLEYHPSPDQKDGPAFWLDIHDFTGDFETNVEKMSDWLPEYFSDIDTGWQKYVVYAQKMAQPDASPGDAVYTTKDNLSVIKKRNSAIVLDHDVAGWPTLPLPPAAPNHGIPAPEKLKDAQGLLWAFVTAHYQKASGRNSVKVPWNQLAANNREFLAMEYCPPGLMLCDPSNMGIDTIREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2X3</accession>
    <name>A0A9P6E2X3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="13">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_778601</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="13"/>
    <dbReference type="EMBL" id="MU158037">
        <property type="protein sequence ID" value="KAF9521517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2X3"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006720">
        <property type="term" value="P:isoprenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000036">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="25"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9521517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="29619" checksum="9EE415862D14D895" modified="2023-09-13" version="1">MNPFESNVSLDMQGSFESTDTHKYSVILPTYNERKNLPVIVWLLAKMFKENGLSWEVIVVDDNSPDGTQEVARELASVYGEDKVVLKPRAGKLGLGTAYIHGLNFVTGDFVIIMDADFSHHPKFIPQFIRLQKAHNLDIVTGTRYRSTATPYSAEATPGGVHGWDVKRKLVSRGANYLADTVLNPGVSDLTGSFRLYRLPVLRHIITVTVSKGYVFQMEMMVRARALGYSVGEVPITFVDRIFGDSKLGAGEIVGYAKGVWNLFVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3E4</accession>
    <name>A0A9P6E3E4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_740920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157991">
        <property type="protein sequence ID" value="KAF9521769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3E4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8598" checksum="C88795EB257C7CE3" modified="2023-09-13" version="1" fragment="single">FGQEKPRRDEATFLIQTIAHQVAIDILQMQEYIFEMIFLDPTICTKCIDVQLQHLLVDPSKTRQSALSHQAIVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3J8</accession>
    <name>A0A9P6E3J8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157984">
        <property type="protein sequence ID" value="KAF9521833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3J8"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="595" mass="68275" checksum="DA2C429EC514D1F7" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3K7</accession>
    <name>A0A9P6E3K7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_742959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157980">
        <property type="protein sequence ID" value="KAF9521862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3K7"/>
    <dbReference type="OrthoDB" id="3229882at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="15375" checksum="8BEF73BABA867716" modified="2023-09-13" version="1" fragment="single">TDDILARSNHHSCHFTVTDKSGVPIQKGCLNQDGNCKARFARETFEETMVDPLTGALRMKKGEPWMNTFTRPVSYWMHCNTDSSSLLSGTAVKAVIKYTTKYITKAGLTTYSIFDSVKQVLSKNSELLGGTTDCKQAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3X4</accession>
    <name>A0A9P6E3X4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_919695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157962">
        <property type="protein sequence ID" value="KAF9522089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3X4"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="46"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="224" mass="25264" checksum="091871E3A23C9967" modified="2023-09-13" version="1">MTERGRAERRSAVETELTLAKAKISQLQRGLFDIRQRLNDTTPILDILPADIMVQIFQHLLPRHLDSEIAGYGCLVKPVQLMLGAVCRTWRSIAWKFPGLWKEISLTVADPGCTEVRVGLVQEWILRTGGLPLRISLSVQATEDDAVLDRVLRILLQECWRWRTFEIAGNATHQLRTEMSEGDYFFPMLTSISLGANSHTVPSPMKIPWTFNTDFSLTAAGIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3Z8</accession>
    <name>A0A9P6E3Z8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_899979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3Z8"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="306"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="198"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="372" mass="42513" checksum="7CCD991C74E37399" modified="2023-09-13" version="1" fragment="single">LFSPRSVSHTYGILWLYGLLNILKGAPRLLKPPLQEGTARQAIFERRYTHSRLYTIIPFNRAPESGGGFVLLPETAHAYKSLQDRSGIILRESGLANLNTQHLEHEVRGAINLRQIPGTLIYAFGHPVFGLLPVAHPTSLQYFQFPAWRICLVGMPKTNSCSHQRQRFKQPTPQQLLDIRYKEISSGSEDEKTIKDSLATVRSQLRLSKEELKQHKKRLEIVNQEISALRTLHTDQEAKLEESSREVASIRDEHNTKMAEIAEVFDALSAGHEQEMQSTAQEILRLQSLLAKSSRTNEQLQALVDCDVCTQNIMRPFTLESCGHTFCYGCLRAWFLVNREKFEMEHPMYDPTRRFEKLSVADTFQIAQNLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4B4</accession>
    <name>A0A9P6E4B4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_899798</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4B4"/>
    <dbReference type="OrthoDB" id="3496539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040136539" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="19"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9522240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="232" mass="24377" checksum="3A2E5F7AA42304C6" modified="2023-09-13" version="1">MFNKVLLAIFSLTTLVSAHYTFPSLIAGGSTQGQWVNVRRTNNYQSNGPVTDVSSADFRCYNTQTAAKATTYNVTAGSTIGIAPGGAVSHPGVLNIYMAKAPSGVDVANWDGAGQVWFKVYQISAVTNGGQSITWPSNGATSYTWKLPQSLPSGGYLVRTEHIALHSASGFQGAQFYISCAQINISGGGSGNPGPLVSIPGVYTGREPGIMLNIYYPIPTTYTQPGPAVWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4E5</accession>
    <name>A0A9P6E4E5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4E5"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="41"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="586" mass="67023" checksum="FA39C432B84B8AB2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E542</accession>
    <name>A0A9P6E542_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_871919</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E542"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="183"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="664" mass="70112" checksum="4212870D2213303D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Q8</accession>
    <name>A0A9P6E5Q8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_910972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Q8"/>
    <dbReference type="OrthoDB" id="3251775at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="36381" checksum="E46E29186FC90138" modified="2023-09-13" version="1">MSDPSQAYADFIIQAVRFTRISRYPVVAGYTALLYEFLIVFDQEYRLIYKSQWTLLKFLYLACRFIPITLWPVNIFTFMNEHTRQACQPLVVFFSLSFAPFLALPQCVYVLRAWSITGRKTSLLAIFSSCLAAYLGIVLWASTDDLRVIEAGFNTFGKAGCYRGSYRHQNPFARSIFAGIVLDFIVATIMMIYYYLTIRGSRGRLGRLVLKQDMFFFPFMLALNAWAAIMFLSPIRFLDGIVFTSVFVTSNILTCRFILQLRGLSSPTEHTELIRLSGVVRRDLGPASAMPNFERSNRASIALPVANLEPVPSHSHVSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5V7</accession>
    <name>A0A9P6E5V7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_63851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5V7"/>
    <dbReference type="OrthoDB" id="192148at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="48230" checksum="D4B6B5543FE1520E" modified="2023-09-13" version="1">MSPTNSSPKPTTPNELTSTTKKSPSPSTWKETFANGAILSLEVVEQAAKFAPVPYLADAAGSALSIVKIIQDAHDNKGDFQQLAEDATSIVSAIFNSYNKSDNQKEWPGDHLRDVVIDIANTLKEICDFVEARRDKNFILRMINHESDTKDIKAYREKLNLAIRKFGVSSHLEIHEMLQELTKMIVRLSKQIEELKEHENCDTVQNPKKKSADDESSREKAAELKDTETRLDKLRKKEAEFLGEIRQRRERERIRSIIHVEDEDEDIDEGVQPRQRSRSRRSPRSTPDDAISEGLSNLNISPAPPSYEASSSSSHTPSPRSQSHSPHPFNQYGSPPIPQPQQFPFYPNPNGGSPYPQGYYQQPYMTPYGSPYSPPGGYGYPYAGNYTTNVNSGNMTVTNTIGSNNNSSTIINEGRSRSRRTFFKLFLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E629</accession>
    <name>A0A9P6E629_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E629"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="195" mass="22465" checksum="E4B48501DB3A27DD" modified="2023-09-13" version="1">MSDIELGLVFFIKDDDPLWEDELELFDIRKNFVSVYSPIYHGSSVFKAFAATVFDTWSDYLTCAFFSTTSAWIAVATISLCIAEEPLQAQGRPLMVGVHDRIVKPGSFPFSLNLTRFSTRLSSEITDPELPWFEYEGEAYQKTLIECHHSDYNFSDWRLDISEGDIYMLDASTDMLKNPPVDWDDAEWRENDGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E635</accession>
    <name>A0A9P6E635_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_863218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E635"/>
    <dbReference type="OrthoDB" id="2564904at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040320042" evidence="3">
        <location>
            <begin position="22"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="37578" checksum="0EBD96956CBA8B8E" modified="2023-09-13" version="1">MQLKMLSITLVVIAVASGSLAQVTGTYPAVPLISKHYASPADLPYKVDTDTGLVRGQQTGYNICNSTTENQQSLCQTFYFNAHDDFCLTAPPNPGKTVADQEGEMVAWCSKKGHGTRLIPNGAIKGLEFRKTPDYIQIVGKIDQTLINIPEGDYGGEMDSGGADGRGNPMGGVFFSTAWGGSSPIQASHWTCFMGGDMFGCKACDPSKSNPRRHCEHIYDRIGIVWNMPSNAKEGEFVSCDADNAEFVGVYTSNGQVLTYTQPPESLGAISTMPYTPTIPPSSNCKTFASTQLFAALPTGSSSGSTSGTITGSGGSSKPTGSASATGSGSAGAKPTDSGAEAIAVSAAASVLGVLFAALFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E651</accession>
    <name>A0A9P6E651_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_863231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E651"/>
    <dbReference type="OrthoDB" id="18798at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="20219" checksum="10577239BD71E3C2" modified="2023-09-13" version="1">MESFLDPTLCISGYSYRKIWLIDSKTVTLDIIDAPSEEYYMAVREQFVKGADGILLVYSVTNRTSFGEVMNLYNLIRRVKEPSEESIQVVLAANECEQDGEHAGERVVSAIEGQNLAKNIECPIYEISTKGRQNLEEPFHELVRMIRRYKLRSEVLDGRADSLEDSSKNTQGSRCIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6T6</accession>
    <name>A0A9P6E6T6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_871646</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157917">
        <property type="protein sequence ID" value="KAF9523453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6T6"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="21"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="416" mass="45291" checksum="DEEAEABFDFB2C002" modified="2023-09-13" version="1">MICSYRECPLLKKLSPLPWPQFSIVLFLLLADPLTSQIISPFAPQLIRDIGITNGNENQVGYYVGIMQSCFFLTQAMTVLHWSRLSDSIGRKPVILSGLVGLAISMYCFGLSKSFLGLVISGSLSGALNGNLGVFKSMMADMTDSTNMSKAYAYLPIVWSIGSTLGPIIGGVLARPAERFPDVFGHNEFMKKYPYFLPCSVAATFSFIAWIVAIFLLKETATNPQNLVVAAANYVILSLVDIAFQAVHPLFLSTPINLGGFGLPPPTIGKILSLIAVLDGIFQIFFFAKIYGRWGPKRVFITGLLSAIPAFMLFPIINLLARHQGYSLAAWIAIVAQATVFVAVNCSFGAIYIFIAAASPNRASLGATNGLSETTVSFMRAVGYLGGYLVYLILLFFTFISLCIGWLLPQHIQSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6T7</accession>
    <name>A0A9P6E6T7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_862508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6T7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="452" mass="43836" checksum="6D57E7B485C26ED6" modified="2023-09-13" version="1">MITITTVLPPGSVVSAPPLNTAKKGNDHTGAIVGGVVGGVGGLLLLLLLLFFLLRRHRRYKDDFDGNFDPVAVSHNKQSSLGRTTGGGAGAGGLGRATTGAGATLPAVGTALDEEDDGMGGRIKAGVGGGGVISPYPFGVGGVPGREAQMSQVGAGAGPSAYGQGQPGGHAGYGSVPVGGILGAGALGAAGAVAANQHQSQNQNQNHSQQNLGHAHGGNMYVNEKGHRRLSSGGGASVSAVSDGGTNASAYGGYVPQSSQGHGYAPGQLPTPAPFGMAAGYPHSAQPYGPPTPVTTHTTGGTSSLGFGGVGGGRGTNTMTSSGSEYSAPSAPLGGGRSAKEIEAFGVGGVGAGVGGRAGRGKGARVVNPDEGALGGQQGPGQGLYGGASVPGSAVGLGVPQGQVGAGEGAGEGVPHGPVVHRDGGRVEPEHEEGTMDEIPPTYDSLPVDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7I4</accession>
    <name>A0A9P6E7I4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lectin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_646109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7I4"/>
    <dbReference type="OrthoDB" id="3153136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44103">
        <property type="entry name" value="PROPROTEIN CONVERTASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44103:SF1">
        <property type="entry name" value="PROPROTEIN CONVERTASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="428" mass="46203" checksum="625122C772DD8A7E" modified="2023-09-13" version="1">MHAAGRVQSSLKINQVCVHSYSRSFRTDLTLNLFEAPVSGRGSAEVLAFGLHGVVTLRNITSSNPQLFNIINDFAFYKGGWRTERHVRMVADITGDRNPDIVGFGEHGVHVSINNGDNTFSPARNVLNSFAFSAGNWRVEKHIRFLADLRGVGRCDIVGFGDRGVSVSQNNGGGHFSPPTLVLVDFGFNAGGWRIDRHLRFLADVTGSNRLDIVGFGERSVCVARNNGDGTFAPAQAVINDFCIDVGGWRVNHHPRFLADLTGDGKVDIIGCGAGGVYVSLNDGHGGFGPVKLVLSDFGTHQGWKVDQHPRFVADLTGNKCGDLIGFGSAGVYVALNNGNGTFGPVNLVLKDFGSQQGWSVQNHPRFVADLTGRGCADILGFGEKAVWVSLNNGNGTFSPVRKVTNQLAFNRGEWALDKTFRCLVNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E842</accession>
    <name>A0A9P6E842_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E842"/>
    <dbReference type="OrthoDB" id="2535105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8101" checksum="DA606138E0180487" modified="2023-09-13" version="1">MALATLDWAQPLDDSNGVVYIGILVSAVLHGGCILQALTYFQPQLSQVATTVMVDSVHIILISAVLNGYLIRNFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8S0</accession>
    <name>A0A9P6E8S0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8S0"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="468" mass="55540" checksum="25FFE5CE07B125FE" modified="2023-09-13" version="1">MNKLNKYFIKREIRADEQRFWEFWASYAQKHWRMMTIKELDNIPLTVEGKPEDDMETAARMLSLTDAYWERYSEHYGSEGSSRGQELDQRSYELLCKNLGQWSSPSENCLSRICRWDITSTKQRVIVDRVFSWQKQLQDRRLHSGIVYHLVLCCLRDEDNSDCVKALFQLYRGVMEMDCDFFFARSKWPQFIFSLHLARQEWDEAESLLAEYPALTTNSSDLTKAKDYAYQGEIQMKRGQEMEGEITLRKGVEIECEDDDWKGQSASGHFLCCEQLLDLYLQQARWSDAKSLVIHLIEAKESRMSQDGPKATSEHWQWNVAARRATRVIKMNRWRLFDKIKEDDHGNERVYFLHGLYNNKRQLALVYIKLKRKSEAQVLLEELLEDKMHMENPILLASKELLVDLYTELEKLDEAEERQEEIIAAKSSSFGYDSEKLIPDLERLANIYQKNNHLGKRHHVKLRLLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8Y8</accession>
    <name>A0A9P6E8Y8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Copper radical oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_772953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8Y8"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040106720" evidence="4">
        <location>
            <begin position="22"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="645"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="5">
        <location>
            <begin position="208"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="6">
        <location>
            <begin position="492"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="609"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="625"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="796" mass="85254" checksum="028FFBC15E44B281" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9A5</accession>
    <name>A0A9P6E9A5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNase P subunit p30-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_773041</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9A5"/>
    <dbReference type="OrthoDB" id="17948at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002738">
        <property type="entry name" value="RNase_P_p30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01876">
        <property type="entry name" value="RNase_P_p30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="38852" checksum="83AB6B7783EF6342" modified="2023-09-13" version="1">MFFDLNVPITKKISANTSKKGKGTGNEALVSYSPAEIAAVEHRIDLQVHLGYTILSFCQTINKRVDPKVHVNVLNPLVALLRKRPGIVYLKRLNIILDQDSEKGFGLINANVTFFNSYDLLSLCPTTHNTFNQACLTHSLPSNLTAHIISLPSTLPRLPFHLKHTLIRTAIKNGAVFEINYVGSLGAEQEPTLVDANAAESGPAAKRNWWAATRELIRVCKGKGLILSGGCVVECDLRAPRDISNIISILGLAQDATHEASTKTPKSLILRAETRKTYRAVFSEPTVVLPEDSQIRSSVPGPVEQMEIDPDSSQVSVSKRPHEDSEPLNVPRQSAAAQPSKKKKKKPNKSDKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAD0</accession>
    <name>A0A9P6EAD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_796373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAD0"/>
    <dbReference type="OrthoDB" id="3343770at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="307" mass="33535" checksum="14F53E8677522307" modified="2023-09-13" version="1">MHTDSERLYVDLIFRATRKYPSWDPEIQIKVGDYGRITKGEASWRDWLTVLGLNAKQKGIFVKEGNIYEDGIAQAFDIPAAVHQGGGRDEDVTQRRLQAAASDDHDGVMWVTSKNVRTMSKDLKLGGGLQGLANLRLHAGFKLTSGRGAILAMEHETVTYLDRPGSLLKLLMSERLHGRVIVSEVHQCSSYARYLVSEGGKTVSIGLGAEVPCPGAPGVSALGEVAGSWYCDAAVGNFKAKINQVGEKVFCPLYRLVAVEERRPCVGLRGPIEQAGLSDVEPPWTPVEDEEEDDFAALGTQGTWSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAL6</accession>
    <name>A0A9P6EAL6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAL6"/>
    <dbReference type="OrthoDB" id="3039255at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="56897" checksum="8D84173DCC191E41" modified="2023-09-13" version="1">MDDLPYEIWYLIVQYLPSDEVENLFSVSRALFNIALDLHYREVHLPGRARGPLMSKHLKKINIYHLRNPLVVSRPREVHILDLFDPWPGVQAKKSVLESARKYLFKSKKPYASQTNALKQVVEIIPFLTSVTTLHVEKGFEGFLQNPEVLNSGLFFQCWAAFGSQLKVLSLATPLEIFHRVTGQDLHLPCLEVLRMQIWDCFQTTEPNSIISTQVIPFIQRNQATICNLKLDIEDYTIDVSALLGPLESMCQLSSLDLKTSYTNCLKTNFIGLERLLRARRHELHTLRIRTHHYYFSQRFQTFAEFFQSPCWHIPLPKLKTLDIEPPLSEWKDLEYAYLVRFKSSLTTLRLSPNIRWQYPEVACLTNILTPFENLKYLELLVFSMSPALLSLFATSIPQLETLRLFYKYIFANLMFPSEASERFVEELQKYNNLSSWNLKELDYCESLRTVVSDGKVEVALVDKLSNVQWFCGLYRDEFKSRFIKLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAZ6</accession>
    <name>A0A9P6EAZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="1667"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1176"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1565"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1602"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="920"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1301"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1319"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1349"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1371"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1395"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1472"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1517"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1573"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1610"/>
            <end position="1631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1958" mass="207863" checksum="26F8E3E36787890B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC47</accession>
    <name>A0A9P6EC47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_795112</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC47"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="17">
        <location>
            <begin position="445"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="319"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="393"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9526319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="774" mass="84501" checksum="9A49AE486CAA995E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECR7</accession>
    <name>A0A9P6ECR7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Member of major facilitator superfamily multidrug-resistance, DHA1 sub-family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_769825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECR7"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="25"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9526687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="493" mass="53828" checksum="7CB6512DA1B952D0" modified="2023-09-13" version="1">MTSRADEEAPLLQGKRKPTPLPWSQFSIILFLLLADPLTTQVISPFAPQLIRDIGITNGNESQVGYYVGIMQSFFFLTQACTVLHWSRLSDSIGRKPVILCGLVGLSLSTYCFGLSRSFWGLVLSGSLNGALNGNLGVIKSMMAEMTDPTNISKAYAYLPIVWTTGSTLGPIIGGLLSRPADRFPNVFGNSEFMKKYPYFLPCSVPATFSVSAWIIAFFFLKETSANPQSIAQYLGFRERKTEAVENPVIIVTSTEEEPLITTEPRNLDGEALSIDEPLPLRSLLTHEVVIAATNYAFLSLVDIGFRAVHPLFLSTPIELGGFGLPPATIGKVLSLFAVLDGLFQVFFFAKIYDRWGPKRVFIAGVLSTIPAFMLFPIINALARHQGYSLTAWAAVVAQITMFVAVNCSFGAIYIFIAAASPNRASLGATNGFSEMTVSFMRAIGPAITNSLFSLSMAKGYLGGYLVYFILLLFTGLSLCIGWLLPRHIHSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECV7</accession>
    <name>A0A9P6ECV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_870277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECV7"/>
    <dbReference type="OrthoDB" id="3199698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="796" mass="90829" checksum="7046B800A3FD914A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDK5</accession>
    <name>A0A9P6EDK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_436036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDK5"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="423"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="620" mass="71180" checksum="631C73180835CEEB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE59</accession>
    <name>A0A9P6EE59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sucrase/ferredoxin-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_816028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE59"/>
    <dbReference type="OrthoDB" id="10253744at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="280" mass="31717" checksum="A3291B62940271BB" modified="2023-09-13" version="1">MLLRVRHFSRPRKRIWNKSLSTTHRPDSESPPYFVGHPVGTVKPHRCSIFLHANEPPSSFPKAGPSSPISREIQLRGSQWGSSAANFCWMEHFASEDWFGRQPMTVYSRNGKLDIPEVSLENIDEVEHKVLSFLDGPTTDVERVVESGYADLYVCTHGARDCRCGERGQQMYDALLRTVEEEKLRSPNGVAHRIRIGATGHVGGHQFAANVIVFPHGEWLGCLKPEDSGWLVSRICADLERNTKSYGPSDSPFHLEHWRGRMGMSKEETMQLYEASRQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFG6</accession>
    <name>A0A9P6EFG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_894349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFG6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="27718" checksum="B0E348F68BCDFF1F" modified="2023-09-13" version="1">MSLLLEHPPFLDPFRDILSAALLCSSSLLVELRFACQYDEDGDVDPEYQIPTMRVNDTCLAPLLQMKNLTTLNLDPELRVDAITDQFLHDVAATLPALNFFVIGLSSLYEVVPCTTISGIQVVLESCTHLQTFHVPFKLGGILALQEVVVGLKNFGSLFAAHQPDAALFHAELVRMRPGLERVTVGYHQNLKVVTPWEQHPASDEEEEICTTEYRGCRFEKIMRQVFFYSTRQSFCLSDEPLQSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFT4</accession>
    <name>A0A9P6EFT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFT4"/>
    <dbReference type="OrthoDB" id="2340858at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="30236" checksum="68FABDD7177F360B" modified="2023-09-13" version="1">MDLDFGYTSLVETPGAVVVTDANDTIRDCIELFAAGNMFSKDLNQPFYSIWQEYWGRKLVLHTEFERHPAESELTLNQVFQYAIKASKRSTVSLKVPSMPLCDGQYESMVLRNDILDIDKSIEEDLGKGDNSFVLTSKPGVGKSTFIAYLLAKRLSERKPTFYHCPASSPNSPNDVFLFHGGGVARLTQTNTNIYLPLISAKILGIMEPHIGPYQPPMMFFQQAHPFVYAMSAGDEHQRWLSKLKKSFRTYTLKDWEPKEIFQTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG03</accession>
    <name>A0A9P6EG03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_906989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG03"/>
    <dbReference type="OrthoDB" id="3256331at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="2">
        <location>
            <begin position="28"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22363" checksum="63ECA3BC3F07B2F6" modified="2023-09-13" version="1">MMPMRNSLASSSVYSENPLLSQDSESSFWVDTPPFDQSSSNKDSVYTETGSDSSSRITQSVNKAALTFDRNSVINGVVYLNDKLVYAITTNASGTRTDICNVHEQQWTFIATDTGNFIWKTSSQYRLALFSEDDSRQPIAFTYRSDRAQPPVLNLQGGSRILDDILVSFVVLEQRMRMKEKRRQNGMLYGPLTETGICP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGA6</accession>
    <name>A0A9P6EGA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_765998</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9529013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGA6"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="15">
        <location>
            <begin position="25"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="245"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="501"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="501"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="561"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="617"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9529013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="653" mass="72288" checksum="BAC2BADC8B5174A9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGG3</accession>
    <name>A0A9P6EGG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGG3"/>
    <dbReference type="OrthoDB" id="1106148at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="152" mass="15339" checksum="69E6FF1B27D4058B" modified="2023-09-13" version="1">MPRQSRGRASAPAPRAAPAPAQSRSAHTASAPAGNYAQPHAPAPPAGATSHAQPSQGPGMLGQMAATAGSVAIGSTIGHGLSSMLFGGSSSAQEAPVQQATPVQQQNGMGIQCEAQAKDFTKCLDKADFQSCSWYLEQLKACQSAANSFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH07</accession>
    <name>A0A9P6EH07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_298215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH07"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="34394" checksum="AAA4BCEF45544BB5" modified="2023-09-13" version="1">MPTREIIRIETEREDGFTLPSDCIIRPHDGRKPFIVRERHLMMPAIEETSTNLSTLTVYRGDRAPESKDIAFERRNGEVYATLIQSQTTSSEVDDGSTSFITTVRFKEELRSLPQPVVVLTNPTIGPVVGPSIASLPQAPSAFTQPDNGSTYFTFSRANTMPIAPLAVPQPPPALVAGGPNLPPPPAIAHAPLLHPAAPFPAVGASTPASTASPSTSHRRFGLFGAFSRFFEPETPPLEYWQHYQDTPYIGIKRKWCDDELCESSSSKRIRKTLLIGGAVVLASALFQAGVIEAGALPWKPIESSTSMGTPWLHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHH4</accession>
    <name>A0A9P6EHH4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_835452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHH4"/>
    <dbReference type="OrthoDB" id="2864564at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="604" mass="67904" checksum="2E6DB284F656FF2D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHY9</accession>
    <name>A0A9P6EHY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHY9"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="62105" checksum="0A1580E214AAF186" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIY3</accession>
    <name>A0A9P6EIY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable threonine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_850485</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIY3"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000019">
        <property type="entry name" value="Threonine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000003">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000006">
        <property type="entry name" value="Threonine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000005">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="15">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="387"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9530531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="776" mass="89248" checksum="D3F0FBE626C54882" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJA4</accession>
    <name>A0A9P6EJA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_905564</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJA4"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="169"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="339" mass="36910" checksum="669DDB932F1BB979" modified="2023-09-13" version="1">MDAVRYAAPNQLDIVNVPIPEIQEDQVLIKVTCCGICGTDRHLAEGEFIGKFPLIPGHEIVGIISQIGSSVKGLIIGDRCVADNTILCDSCYYCRRGQYLLCSNFDSLGVTKAGGFAGFVAVHSKKVFKINNLTDEEATLVEPAACAIHGMDRLRPSVGVEAIIFGAGPTGIILAQLLKINGASKVVIVANKGVKTKIARDLEAGDEYIELDRENPHPQWAKLKDEYQGKFDIVIEATGSQAIATDSINFVRRGGSLLIYGVYSNADRVQWSPAKIFQDEITVIGSFAQTHCFPRAVAYLDSGKIKVKGMVTDIFFIKDFEKALEKLRSKTACKIALRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJM5</accession>
    <name>A0A9P6EJM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_882479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJM5"/>
    <dbReference type="OrthoDB" id="2884999at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="240"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="372" mass="41790" checksum="0DC998E09E838A60" modified="2023-09-13" version="1">MANALSPRTTTSGICLLHVGDWDTFPMVSTEAECSASLGLVPFFCALNELQAFNSSFVGWMSNFVAPFACAGIWGLTLIQTLVYFFNYHRDPLPLKFYVGALWLVETLHQGSITYIATTPNRTDLILFTRGSDIILNVLPYLCLAYITFMAQLFFAYKLGKLLHMPSATILCLLPFILFQLTIPVHMFVTGRQLHLLGWPKTMVYSDKFQTTVNTFDRTYFSKALIIQRNHLVAALVTAIFVNCTLAGLLGSHLWQWYFRTPSLVFKSTTPLFYRITFFSFNIGIWSAIGAVLSLILVMYFPNNNVSAMKHIQALSSLYASSVLANLNARATQNPTGAHVFLPVPKDETIVLEPLRFRVQSSQTISTIWKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJR7</accession>
    <name>A0A9P6EJR7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_763959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJR7"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.660">
        <property type="entry name" value="IL-4 antagonist (De novo design) like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF108">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="710"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1006" mass="111268" checksum="3EF9450FCCE48C91" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJX3</accession>
    <name>A0A9P6EJX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJX3"/>
    <dbReference type="OrthoDB" id="3043619at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="47736" checksum="6131213D1602CFB1" modified="2023-09-13" version="1">MTSRLIPQAEAMFFPENTPLPVEITSLIVDSVMVTCTTKEARFTLRSCLVLSRSFWLSAREKLFRVLNIDETLGREAAHRLASLLSLVRPHDALSIVPCIRELSISFDSPMFESVLDDRNGTLADILTNLSSPGSQVTHFSLQCDEEPGLNWVNISTYLNRAIRQFTKIGTLDAVVIRNVYNLPIPFFHGGHFHDLRLAGTSYRLSQMVPMLTDAGDFVMRDPEAGPGPPPSLHSLSTHNDSLLLCFARPNEAPLATLHSFKTSVFATTCIENIGLVFQQAYQSLETCSLKLRPQSNSISNLPKFDALHRLTTLELLIPIDIQSNMEDPLIPVASLLNISAPISRQVHMTVIFLSSRKMDIHLINHGRWNPIDRNLADPMKFGAAGTKEIELRGPGSNSPAGLKVRGWLQKSGLRRCFSAGRSPYRLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK05</accession>
    <name>A0A9P6EK05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_849433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK05"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="66"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="40355" checksum="1A9DE26BD00A456E" modified="2023-09-13" version="1">MEETSNIVSELIETGFADLDVQPTTTDARRRNVGWRANAAFMVIYKEYRQSISPILRRHRSSRLNVDLFWKMPIDILFEILTKLHPIDLLHIQKASSEFCLALEFLGESIWKAVYLQVEFPAPPPGASYSKWTASLFAPQVCEKCNNDPAPLNHLTHQRLCEECHHKLFTDHDAESETKELCAQSKFSFFSFDRQNEQPGDNPFDLFWPTYYTSDMAAIGKRLSDLKRDVEEGLERATDNLKEYRASQAKIRSDVEQSAIDWGMWSLHLGRRINNIIDVGLYRMEIQLKNRLIASEAFAAADVNNFRYREMLSSYISDNCVFSVNRRRSAQVRRFGLVELRLKSIQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK26</accession>
    <name>A0A9P6EK26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_850700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK26"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="37271" checksum="5C38AFA085EEA142" modified="2023-09-13" version="1">MSIISTPITELFGIKHPILLAGMNVAAGPELAAAVTNAGGLGVIGGIGYTPKVLRQQIQFIKKDLKDKNAPFGVDLLLPQIGGNARKTNSDYTKGQLPELIDVIIEEKTKLFVCAVGIPPEWAVEKLHKAGILFMNMVGHPKHVKKALEVGVDLICAQAGEGGGHTGDIAASILIPACVDAVKGHKSPLTGKPVYVVGAGAVFDGRGLAANLSWGAQGVWVGTRFVASTEAGAPPMHKQQVVTAGFEDNVRTLIFTGRPLRVRKTPYVAEWEEKKQAEIKELTSKGIVPVYHDLEKHPEKSMEARAWLMGSVSAVINEVLPAQTIVDNMVTQAAEILRSNAAKVNPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKD2</accession>
    <name>A0A9P6EKD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_762505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKD2"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051831">
        <property type="entry name" value="Bromodomain_contain_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881:SF27">
        <property type="entry name" value="BROMODOMAIN CONTAINING 7_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881">
        <property type="entry name" value="BROMODOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="95"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="833"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="847"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="931" mass="102224" checksum="02146B07880AC370" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKG4</accession>
    <name>A0A9P6EKG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKG4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="743"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="781" mass="85499" checksum="97B8DA7DC4CF96B1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKL1</accession>
    <name>A0A9P6EKL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_919728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKL1"/>
    <dbReference type="OrthoDB" id="3226582at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="39019" checksum="72CF4809191DFC0F" modified="2023-09-13" version="1" fragment="single">MISSNLSARVDIFIRALFVQVCFSSAAIGVEFFMWIFGLFVYFETPKDRRRGRAIYLAISFAILVADCWARLPLAKYSFEVLYKPSNTEEILNIEGDLLDAWYSRASNWASQIILWLGNGLLVYRCRIVWIDKPIVTFVPFLLYLGGTAASVAIFAVNTTSLTNIPVANQLMTSSISLFISVNIIVTLLIAGRLINMRRRQAAIMTTFDSKMYIGVISILVESALPLSIIGILHLAASQMSTNVLLLKWRVVHFVFLILWQACVALAPQLIIFRVTIGRSWALESNMSSHLTVLAFQADTVDTFDTDRDVEGSIYNQRKDEPTSTGLQVNESASVISEKYELGGLSTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKV8</accession>
    <name>A0A9P6EKV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_79529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKV8"/>
    <dbReference type="OrthoDB" id="2840428at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="10006" checksum="8A5538CA7CCE0BCA" modified="2023-09-13" version="1">MCRLHTEGIEHGCGHYIITRKVAKDDCRNKFCMNSETHPPGRCNSCGENCKRYFDPDASQHVTNRTGDYCVQCMYWFKGEGARRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL83</accession>
    <name>A0A9P6EL83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL83"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="17546" checksum="0ADA0D7B6130C8CD" modified="2023-09-13" version="1">MVPFTIAEDVSLEIVLVGIISCFPDLSKKDIPTFNLLQNPQFFGGFPYSLRTWQRFSKIRKMSTASIEPLDPTQLLADHERELHLIVDRKLRITKEDPIVAALGPQGEEVIRNYTNIWKLDDSNHHFIVREKSGSLSLLERRENGDNLNGGTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELA4</accession>
    <name>A0A9P6ELA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_847965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018507at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14037">
        <property type="entry name" value="STKc_NAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000853">
        <property type="entry name" value="Related to ARK1-Actin Regulating Kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="30"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="381"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="453"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="580"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="913"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1256"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="670"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="700"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="737"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="791"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="913"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1028"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1094"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1146"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1188"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1286"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1308"/>
            <end position="1317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9531881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1340" mass="145495" checksum="57B61C9CB5EB56F7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELR9</accession>
    <name>A0A9P6ELR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl hydrolase family 85-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELR9"/>
    <dbReference type="OrthoDB" id="284473at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033925">
        <property type="term" value="F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032979">
        <property type="entry name" value="ENGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005201">
        <property type="entry name" value="TIM_ENGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246:SF1">
        <property type="entry name" value="CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246">
        <property type="entry name" value="ENDO BETA N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03644">
        <property type="entry name" value="Glyco_hydro_85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosolic endo-beta-N-acetylglucosaminidase TIM barrel" evidence="1">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="659" mass="73332" checksum="A66FE72CEB8529DD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELX4</accession>
    <name>A0A9P6ELX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CCL1 lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_109630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELX4"/>
    <dbReference type="OrthoDB" id="5271368at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23715">
        <property type="entry name" value="beta-trefoil_Ricin_CCL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048746">
        <property type="entry name" value="CCL2-like_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21595">
        <property type="entry name" value="CCL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCL2-like lectin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="137" mass="14536" checksum="D68BE8AD45FC2C13" modified="2023-09-13" version="1">MSKVAAGRYVIYSRALTPTGQKLALTFSGTQKEALTISPLANAPKQIWVVKDYNSTTSTIGPDTSNRDQVGNGGGVPVVLPPGGYTWTMQVVDSGYIIQDGGKSASSYWNVGDATDGTKVSFGQDNGILSRWVFEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMB7</accession>
    <name>A0A9P6EMB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Nuclear thiol peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_849092</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="3"/>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMB7"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000157">
        <property type="entry name" value="DOT5p Nuclear thiol peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="15">
        <location>
            <begin position="87"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9531478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="232" mass="25052" checksum="2591BF07F10CB20C" modified="2023-09-13" version="1">MPPKKTTETEPAEPRRSGRIASISKPAPTVPEARPKVPKAPKKRAAEEETTEKDEGSTTKKSKADEAAMDVDTTAGSSTQAASLASIDIGDSLPSLILKNEKDADIQVEHLAKEKGVILFLVPKADTPGCTSQACGFRDSYPDFTSLNYDVYCLSADTPTAQTKWQTKKELPYPLISDPQRVLITALGAAEGGKTKRSHFIFEKGGKLVDKKVPVKPADSPRLALEYIKGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMQ4</accession>
    <name>A0A9P6EMQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial small ribosomal subunit Rsm22-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_42438</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMQ4"/>
    <dbReference type="OrthoDB" id="421327at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052571">
        <property type="entry name" value="Mt_RNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184:SF5">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="570"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="646" mass="72010" checksum="B2D1653A07546FDD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN01</accession>
    <name>A0A9P6EN01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN01"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="68"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="690" mass="79235" checksum="CC7FE1A5ED13D1DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN97</accession>
    <name>A0A9P6EN97_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_867789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN97"/>
    <dbReference type="OrthoDB" id="21550at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="27"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="291"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="337"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="517"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="424"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="566" mass="63116" checksum="25F8E24498E3EE1E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP39</accession>
    <name>A0A9P6EP39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-finger of mitochondrial splicing suppressor 51-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_891054</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP39"/>
    <dbReference type="OrthoDB" id="5282002at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032717">
        <property type="entry name" value="Mss51_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069:SF1">
        <property type="entry name" value="PROTEIN MSS51, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13824">
        <property type="entry name" value="zf-Mss51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51 zinc-finger" evidence="2">
        <location>
            <begin position="76"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="3">
        <location>
            <begin position="237"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="58456" checksum="3A95CAA2CDBC3AD5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPU2</accession>
    <name>A0A9P6EPU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_846525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPU2"/>
    <dbReference type="OrthoDB" id="4991875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40640">
        <property type="entry name" value="ANCHORED GLYCOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40640:SF1">
        <property type="entry name" value="ANCHORED GLYCOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040496818" evidence="3">
        <location>
            <begin position="28"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="20408" checksum="F2D3EFF2F435D6F1" modified="2023-09-13" version="1">MGFKLLTNVALLHASVLILGAGGFAHAQSTTSLFLPGFDPQPLSADVAGVGSDGHTTWAIQKGKPTGTEDPSDFPGTVTLVQGPNDVSMTYAVPGVTMAISCSISASISAVCSEDGQTATVPYEPIAVQLGSTIAGAPTPVPTASGSSASNVAPAAGSRSSSKSPSSTTSQSATLPSNTNSAFSKYSASVWVSLIAVIIPGFMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQA7</accession>
    <name>A0A9P6EQA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_867135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQA7"/>
    <dbReference type="OrthoDB" id="120072at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF6">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040161534" description="CBM1 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="4">
        <location>
            <begin position="286"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="34703" checksum="0CD80BAB9561946D" modified="2023-09-13" version="1">MIAFKWAVLSAFSVAVQAGTILWNGSFSQFSTVADFDKWSWANQVGPYQWYIHGSQATSHYLALDTSYKNPAISSESHGLKMTIDSGATWNSQMERAELIPQTTANLGSGQQYYHFSLKRSATNAPDSTLEHQIAFFESHFTELKYGVGSKPTNLVWMIGGVEKWSTPFTADTWFNFAYDINFSSSTVGLWASTGSSPLVRVVANQAASTSTNSADFHVGVLRIVNRNPPEDWYWSGVYIESGSLTTTIGTGSSGSPTGTTPVTTPTTSDPVPTSTVETTTTPAGPTQTQFGQCGGNGYNGPTTCASPYTCVAVSPPYYSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQN6</accession>
    <name>A0A9P6EQN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_845911</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQN6"/>
    <dbReference type="OrthoDB" id="3851628at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009082">
        <property type="term" value="P:branched-chain amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.80:FF:000001">
        <property type="entry name" value="Dihydroxy-acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050165">
        <property type="entry name" value="DHAD_IlvD/Edd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002068">
        <property type="entry name" value="PRK00911.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000:SF5">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="17">
        <location>
            <begin position="64"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="18">
        <location>
            <begin position="402"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9533143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="597" mass="63835" checksum="FD16BEFBCD0E9902" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQR8</accession>
    <name>A0A9P6EQR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transmembrane GTPase fzo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_873719</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQR8"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008053">
        <property type="term" value="P:mitochondrial fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051646">
        <property type="term" value="P:mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000638">
        <property type="entry name" value="Transmembrane GTPase Fzo1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF0">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="13">
        <location>
            <begin position="213"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="78"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9533172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="870" mass="95807" checksum="C281D281488F5EF1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER37</accession>
    <name>A0A9P6ER37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Chorismate mutase</fullName>
            <ecNumber evidence="3 12">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_845899</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13898"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="3 12"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER37"/>
    <dbReference type="OrthoDB" id="191918at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.590.10">
        <property type="entry name" value="Chorismate mutase, AroQ class superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008238">
        <property type="entry name" value="Chorismate_mutase_AroQ_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037039">
        <property type="entry name" value="CM_AroQ_sf_eucaryotic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01802">
        <property type="entry name" value="CM_pl-yst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145:SF12">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017318">
        <property type="entry name" value="Chor_mut_AroQ_eu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="Chorismate mutase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51169">
        <property type="entry name" value="CHORISMATE_MUT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="13">
        <location>
            <begin position="186"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR017318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9533139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="37452" checksum="F91C618C684A5F96" modified="2023-09-13" version="1">MEAENQRIATPLFHSPLSNFVHRPKFMPSINFMVGEDPLSLDRIRSVLTRLEDTIIFSLIERAQFVHNPRIYQRGVFKELSDMGFNGSWLEWFLKETESFHAKARRYTSPDEYPFSTDLPEPLMPSLNFPKILYPNTINANSSILSFYTNAIVPRITRRSTLALATKKRAQGISGSEEFEDDGNYGSAATLDVEVLQAISKRVHYGKFVSESKFMSDPAAFVPFIKSRDRKALDGLISKPEVERKLLLRLQKKAETYAQDIVLEGEVSHDTNGANGKPYGKIDPDGVVDLYESYIIPLTKEVEVDYLLTRLDGLSEEEIENFAKQSKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERD7</accession>
    <name>A0A9P6ERD7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_890385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERD7"/>
    <dbReference type="OrthoDB" id="2156690at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="50494" checksum="C1D8ABE949174613" modified="2023-09-13" version="1">MASTARLSPLSDCLDSFPSPPVRYEERPVSSRPRSQSVPRAYVSREEQGASRHGESPGDISTTTVVIFDDTPSFHAYTDPTQATQATKAQESTDLSEDRFSWLPYVDTPRSDPFIAEESAEHKPKVANHRDGPTTLLEDFQSPNTECTAVSTDSGQSSALACIGTPKFTNKWPKPSTLKYLDGREGCKKVHRPLIGTPVETIEEGKGWGVIAVGKWAPAKICLVASVSVVFVYGTALLILASMTWFNAWPNAGVMTVADYDILVVITLSACFLVFTAMTGISGTFLDSRPILAVYTLLMLPNLILILAVGYISYKRVTFNLDSKLNLAWLRLYSVPGKQAIQDTLHCCGFYNSMHDPSPSKRCYLRSPLSGCRDSLFDFEHEKLTMLYQVAFAMAALHLVNLLIALLSSNHVNRRFGKGLTPRGYLLNREDVRQEAEKVFYEGIGQNVVSEKGDRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERX2</accession>
    <name>A0A9P6ERX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_480515</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERX2"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF2">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="7">
        <location>
            <begin position="97"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="58408" checksum="385A71247614EB6B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESE1</accession>
    <name>A0A9P6ESE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[RNA-polymerase]-subunit kinase</fullName>
            <ecNumber evidence="2">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_755704</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.23" evidence="2"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESE1"/>
    <dbReference type="OrthoDB" id="204883at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008024">
        <property type="term" value="C:cyclin/CDK positive transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000415">
        <property type="entry name" value="CMGC/CDK/CRK7 protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000270">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="40651" checksum="B17009E18B388443" modified="2023-09-13" version="1">MSIDPDSSPRDPPETLQGQLAVSSSPKDLYSILNQVGEGTFGKVYKARNGLNGGHVALKRIRMESERDGFPVTAMREIKLLQSLRHDNVVRLYEMMVSKGSVYMVFEYMDHDLTGILSQSQFQFSDAHLKSLCYQMLAGLAYLHQKGVIHRDIKGSNILVNNRGELKLADFGLARFYQKRRRADYTNRVITLWYRPPELLFGATVYGPEVDMWSAGCIMLELFTKKPIFQGNDEIHQVEVVFKLLGSPTPERWPHALNLPWYELVKPQQNIPNRFRDAFQKWLTPAGLDLAEQLLAYDPTKRITAVQAMEATYFTSEAPQSERPIGLASLEGEWHELETKRERAKRKERKNPTSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETX8</accession>
    <name>A0A9P6ETX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_843069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETX8"/>
    <dbReference type="OrthoDB" id="4726at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF22">
        <property type="entry name" value="LD29830P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="70"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="24818" checksum="1014547DA5E7FD15" modified="2023-09-13" version="1">MRFGCPSSSSQAVLGSQATASKKKQTRVKQPEGKKRCSARLKAREKKVEDAMKKTVKKAKVVSPPEWTINYIYVGNLAPGTSEPTLRSTFSKFGEIDRVTIRCSQGQYVTAAAVPRAALTKRDRHYATVEFVKPESAKRALRLNGSFIGHRRIIVTISVADLPEVKEIANQRIEAMRKKQGQPALSNTSRPLQRTDTEVFIDYREPASDRNHILGMSFGKGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU13</accession>
    <name>A0A9P6EU13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="14">TC-AMP synthase</shortName>
            <ecNumber evidence="3 14">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 14">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_843071</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Likely catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Required for normal translation, by ensuring translation fidelity at the level of codon recognition, appropriate translation initiation selection and maintenance of reading frame. Also involved in telomere replication. Binds to single-stranded telomeric (ssTG) DNA and positively regulates telomere length.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="3 14"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU13"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000008">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00057">
        <property type="entry name" value="L-threonylcarbamoyladenylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="16">
        <location>
            <begin position="51"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00056339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9534867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="420" mass="45795" checksum="70893603378EFCA2" modified="2023-09-13" version="1">MFLSRFRQIYALYRSYMAPSEFTTQVLKCESATISFNTTSDEPTIASAETLDALKAAARHLVDEGQTVVFPTETVYGLGALALDASCAAKIFSTKGRPADNPLIVHVSSFSMLNSLLPPNYDVPKSYKILMKHFWPGALTLLFPRNGDVIPTIITANQSTVAIRMPSHPVARALIAVANAPLAAPSANTSGKPSPTKAEHVFRDLNGKVPLILDGGACGVGLESTVVDGLHEDGNIRVLRPGGITVEDLERVLREDMHDVGNIPKVLVHKRDYADEKMERAPTTPGMKYRHYSPSVPVTLLLTMPSLSGSQATQPFTELLKTLKKESGEQPMKIGVLAATDSKLWETLDAVHGVDWTRFPLGLTEDPGTIAQRLFDGLLSLEEDGVQMMFIEEVEETREGLAIMNRVRKAASESIRVTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU44</accession>
    <name>A0A9P6EU44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_211061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU44"/>
    <dbReference type="OrthoDB" id="3366194at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="20882" checksum="3B6C907161F32040" modified="2023-09-13" version="1" fragment="single">TLSANITSQQTLTFDQLLQESELPLPGPEYYEARRKLWLTPRPSPPTPPSVASDARERLEEILSQPNAVYNREVWNNGLEKVWKGLSSGGKLKTRLPMNMIIKIVHASWLRDRTWPAGMRAPSSDDDQPQTTTGTNEIAPIASTSSIQADPSDLSEELRPMPTIATSELLELPSPRKINNRHYRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUG7</accession>
    <name>A0A9P6EUG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_843387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUG7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="23415" checksum="83C21678A9DCF238" modified="2023-09-13" version="1">MLAQLALKCLIWGFQPKTTLNVRIDANRDVDALIKTLVAETPGRFQGIDPPDINVEDYLKVEPDTLLSDVFNQERSGRFDLIVERPRELWLNCWLVGTDPSKVVVINPMARQSVQDLRMKIRQFFSEIFNETLLGDFCLYKGSISCSELEEKGNYAPTGPNISLRRKLSDLFSHPHLPDCLDIIIHRSRKRQFLALLPRLTTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV70</accession>
    <name>A0A9P6EV70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Spc7 kinetochore protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_872377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV70"/>
    <dbReference type="OrthoDB" id="5592879at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990758">
        <property type="term" value="P:mitotic sister chromatid biorientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040850">
        <property type="entry name" value="Knl1_RWD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033338">
        <property type="entry name" value="Spc105/Spc7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013253">
        <property type="entry name" value="Spc7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28260">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT SPC105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28260:SF1">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT SPC105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18210">
        <property type="entry name" value="Knl1_RWD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08317">
        <property type="entry name" value="Spc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00787">
        <property type="entry name" value="Spc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spc7 kinetochore protein" evidence="3">
        <location>
            <begin position="787"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="636"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="953"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="589"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="694"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="709"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1278" mass="141530" checksum="2E19FE0CA1656539" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHT1</accession>
    <name>A0A9P6JHT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158000">
        <property type="protein sequence ID" value="KAF9521702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHT1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="15373" checksum="F7786F30020D1287" modified="2023-09-13" version="1">MSRPPSISSICSERSMILLKRVRKSPRLNTPYDSSRSAGITVGPFVDRVAWFALVLDVKYLEPVSASMNLQSQAVFHLYILPKTYSCVPCAVNLQMLPSRLKTSPTILLCSYLEDGKHFASAVNLIEGQVRRAATPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIB7</accession>
    <name>A0A9P6JIB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157966">
        <property type="protein sequence ID" value="KAF9522018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIB7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="370" mass="40010" checksum="CA4B1FB0EF4EF87F" modified="2023-09-13" version="1">MSQPITDNPNAARHKPIQSNQRQQGQSRATPPGQKENLPPTASTIPNARPVREGAGRNMAKLIQQERLDSDDEDLSLKKRKRGRRETTAVSSTLTIGVPASTAENPMAPPKKKQRNKASGGQAGTALRPFDSSLMGAPVPTNVEPPRGQFNSVHSSTPNAQVLDNRGNLTPSTPGAVMTQSTAALPTMTTHVPSAHMHAVGHTYSSFQQSPPMPTPDILASQQSYPTNYQPTAVVSNGNQHQEQSTMLSFNFNNTTSTQGFAFGDEQQQQHFDDLFDGLAGQGQDFGMMSSDFSYQDRNLPADAGKTDLMLPSVNSGTNEEENSETENDEDEEQRKGDEGQAAEDDDDDVASQRNVRGNMPELCGSEFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIK2</accession>
    <name>A0A9P6JIK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157962">
        <property type="protein sequence ID" value="KAF9522079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIK2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="24531" checksum="AD4683CC1853B5D5" modified="2023-09-13" version="1">MYKSPTTKLPKQQHPSIKVTTSGSCLTISLLVGPETHHKRELSDDLAAREPHHETPHESAPIHKGHHKRELYDDLSAREMVNTPLGHGSAGSKASKGLAPGKREFSDDLAVRGLKNVPGSKPLGHGKRELYDELAARGLKNVPGSKPLGHGKRELYDELAVRGLKNVPGSKPLGHGKREFSDDLAARGLKNVPGTKPLGHGKRELYDDLLEERQFEDFYDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIT4</accession>
    <name>A0A9P6JIT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_741651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157953">
        <property type="protein sequence ID" value="KAF9522259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIT4"/>
    <dbReference type="OrthoDB" id="3050260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="12020" checksum="AA7A834CAD87BA2E" modified="2023-09-13" version="1" fragment="single">LVMCPDRKLRWFKDHGRTIQQVNQLKSRVIAFWEKSYKQFSIAAPEPARTTTKPRSQYATSTTEDATRYGLDHIRTYLEESPIPMQTIKEAGGYMKYWFQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ60</accession>
    <name>A0A9P6JJ60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HMG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_776223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ60"/>
    <dbReference type="OrthoDB" id="5598737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040648">
        <property type="entry name" value="HMGXB3_CxC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18717">
        <property type="entry name" value="CxC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG" evidence="1">
        <location>
            <begin position="30"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="29743" checksum="D2811B55C9F0B936" modified="2023-09-13" version="1" fragment="single">SISYKSLPPPIWAKIKSDNQRTLAVMRTIPNLISLDSSSCCPCNSPRVGWYDSSRPVEHRQCFVYGLLEAFSTTIEVQKCSFCTHGFIGPDATDIGIFNLNNRSLFALTLLDDYTSHFTKSETPFVSWVASTACRYQNFNSTIPFIKEKVFRSAWFSYARLLQLDEDMRCPQCGPIPKVTIWDGVTLSFSRKNLLSTLCPPTSTNQHSQVKSEIRLENSLQFIAERSLRKDIVFVLHGPSLELPRVNEVENSRTNSEYVIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJB2</accession>
    <name>A0A9P6JJB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_64672</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJB2"/>
    <dbReference type="OrthoDB" id="19448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040420407" evidence="7">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="139"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="387" mass="39352" checksum="4FB5C00A33BE615A" modified="2023-09-13" version="1">MRFFATSISIVALATSAFAAVTPLRTIETYKGETSGRYIVTLKSGVSKDSVFSNARLSRSNITHDWDIIHGFAGNFNEQTLNALRSNPDVESVSEDGIMHTFATQTNAPWGISRISSTAKLSGSVSSLTFSYTYDDTAGSGVDIYLVDTGVRTTHTTFGGRARWGATFGGYPSADGNGHGTHCAGTAAGSQYGVAKKANIIAVKVLSDAGSGAIADIVSGLNYVKSQAASSGRPSIVSMSLGGSATTSLDNAVSSLTSAGVHVAVAAGNSNTDAGSTSPARAPSAVTVGASTIADARASFSNYGSVVDIFAPGQDVISAWGTSDTATNQISGTSMATPHIAGLIAYVIGRDGNTTPAAISTKLKSLSLKGVISGIPSGTINDLAHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK81</accession>
    <name>A0A9P6JK81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_687007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK81"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="365" mass="39975" checksum="D9664E2BE14E7ADD" modified="2023-09-13" version="1">MLATFVVVVAYARFRKGPELVLAHNPLPPYRGIPDHSTAREGDIQYCIATPEIRRRALPYGHPMTPPRSMAEIFIPLDEGPSFQPSIFAEGVPLAHSDVQPFRRVIGREVVPCPDGFVEVRFEEFSSSRTAWAEEILTAPSQFKANSSIYNLEWRVFSLANAQTLWDVSQFFLVQGGVMSAISFLVMVFQIIFPISSHNTPQDISDGFCNDQPKVISHPDIDEASETLAGSTSNPPLVADVSGEIVANHDVLEQSFSSFSLELQNPLVFDSFADFGPPVASSTEADVAKMLLISEPSFTVDFVLPLSSPSAVDKGKVVQLEDDHEQITPNDASHTVDDLSLPEIVAPVSRSSSVCPAMRYCYDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKR0</accession>
    <name>A0A9P6JKR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKR0"/>
    <dbReference type="OrthoDB" id="3013559at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1090" mass="118461" checksum="9ADB68E195A2C62A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKU5</accession>
    <name>A0A9P6JKU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_871366</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKU5"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF21">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="33122" checksum="E12AB3D62FA45BED" modified="2023-09-13" version="1">MHSDDVGYSTGSSTRGPYNCLKVIGAGAFGKVYQAQHTVTGTVVALKVIDLENGDHEDIALIQKEVAVLSQLSNVPNITKYYGSFLDGSEVCIAMEYASAGSVYDLMQTLPGKALEEKPAALITREILISLVALHTVPIIHRDIKCANILISKTGGVMLCDFGVSALLQGSTNRRDTWIGSPYWMAPEIVSGASSYDVKVDIWSLGVSLYEMIKGHPPLAHLGPEDALKRIGKSQAPKLGEEDSSLLLRNFLSACLKENPEERLSAEALVKDKWIVKLKVQNTVLRDLIPASRQSLPSLDSTQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKW2</accession>
    <name>A0A9P6JKW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UvrD-like helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_909779</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3156807at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039904">
        <property type="entry name" value="TRANK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21529">
        <property type="entry name" value="MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21529:SF4">
        <property type="entry name" value="TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="8">
        <location>
            <begin position="490"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1928"/>
            <end position="1964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2245"/>
            <end position="2322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2075"/>
            <end position="2102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1947"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2256"/>
            <end position="2271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2310"/>
            <end position="2319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="511"/>
            <end position="518"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2332" mass="264917" checksum="4C77A31B283D0BE2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL37</accession>
    <name>A0A9P6JL37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="17">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_838579</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="17"/>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000031">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="566"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1030"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1105"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1141"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1179"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1215"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="19">
        <location>
            <begin position="219"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="231"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1331"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1359"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1331"/>
            <end position="1347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
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    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9524821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1378" mass="149857" checksum="2C44BC7CC391F36B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLH8</accession>
    <name>A0A9P6JLH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_560224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAF9525211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1335"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="346"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="356"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
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            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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        <location>
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            <end position="645"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="724"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="915"/>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1364"/>
            <end position="1379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1475" mass="156929" checksum="BA436C6A8D233895" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLN5</accession>
    <name>A0A9P6JLN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">26S proteasome complex subunit SEM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_885991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DSS1/SEM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLN5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007834">
        <property type="entry name" value="DSS1_SEM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16771">
        <property type="entry name" value="26 PROTEASOME COMPLEX SUBUNIT DSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16771:SF0">
        <property type="entry name" value="26S PROTEASOME COMPLEX SUBUNIT SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05160">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01385">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="11812" checksum="F776CBFD2544D661" modified="2023-09-13" version="1">MSSSSKPSEPSKDSKSDSKTDSKSETQQPHLGLLEEDDEFEEFPVADWKDSETDLAHLGGAAPGAAKSGGDKLWEDNWDDDDIEDEFSVQLRSELEKTKSSSTDMEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLR8</accession>
    <name>A0A9P6JLR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_772660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLR8"/>
    <dbReference type="OrthoDB" id="3222453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="255" mass="28201" checksum="DED6D093EAA31066" modified="2023-09-13" version="1" fragment="single">QVYFDHLVAESRGSPLWLPGPDRRLPIDYRRKGLSVGDVGILNPDGGFSFLFNVFMSSKDSINLGRVPPSFESLSPPDDMDFEERDCFGEWSAVTSRSVKRSDQAFQFESLSDEGAILTMPQGASSTVLQDTERLEDYLNIHIKSWYDFLLRRGRKLQNGDIRVVYGCDKVSTWGIATFLSQSSAQASGQVAFKPPGSDSSIGPTLIYECRGSAQAKTGPQEGDIAEIYLKSIRLSSHHKSSILARGLECFSQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF8</accession>
    <name>A0A9P6JMF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_859086</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF8"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF4">
        <property type="entry name" value="NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="603"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="207"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="845" mass="95062" checksum="4F7D8203BCC794E5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN13</accession>
    <name>A0A9P6JN13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Iron/ascorbate oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_857180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN13"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF812">
        <property type="entry name" value="2OG-FE(II) OXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="184"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9526907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="367" mass="41150" checksum="9D5714CCD585BE4C" modified="2023-09-13" version="1">MSNSASQSDFASVPVLDYSLLNSANTRPRFLQQLRHALVNVGFLYLSNHPVSQNDIQRVIDYIPKLFDLRQEAKDAIRMVNSEHFLGYSRFGAEITKGSVDQREQFDFATKYVSTWKEGDPEYYRLRGPCQWPDEKLIPGFRDAFERYLEQVKALSHSFSSVVAEALGLDPEALSQFYDPLNLRQHRAKIVKYPAINGSNDQGVGPHYDAGFLTFLLQASNHEGLQVQNLAGQWINAPPIPGTFVVNIGLAFQMVTHGLARATSHRVLSPKGSAPRYSIPFFQTTRLDKPLGEDELHFPPEVLALRDARGKVAITESANFSEFASEPFGKIALISRIKSHPDVGGRHYPELFKELFPNGHEGLGTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNU8</accession>
    <name>A0A9P6JNU8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LYR motif-containing protein Cup1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_907377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNU8"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046896">
        <property type="entry name" value="Cup1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20263">
        <property type="entry name" value="LYRM2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYR motif-containing protein Cup1-like N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="332" mass="37857" checksum="D195D89C8327BA79" modified="2023-09-13" version="1">MRPASVSPASVRSLYRTYLRQSNALPHVYLRLFFRVIARDAVEKILSFHAPTLRARNFETVLKSIKKLIRANAGDEHAFQHILDLAYGRKGKLKWELLEPMLHPKGLSTLPKIPAEKPSYPVISEEIKALLISPYSRRTKPLDPNDIEPPRTLPERANVLSKDAMLFGPLSKRREANIRRRFFDIETKKLLPPLRSSTVRSSSFPPRSHLDAISALHDNLQATIGPLGRSPTRTRRERLSAPEEYKAENQEERHSSRWIRRRFRALISRVPELSYGAKGTPVVQPSPLSFLTKSTSPKQMPEADPSTLAWLQLPTLNTNKIKTRTQQKSTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNW6</accession>
    <name>A0A9P6JNW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 105 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_426357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNW6"/>
    <dbReference type="OrthoDB" id="540611at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF8">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040214027" evidence="2">
        <location>
            <begin position="25"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="399" mass="44565" checksum="6F3A40A76B761279" modified="2023-09-13" version="1">MPGLMSWTTATSLLLSSWITICSARPSSYAEWAADSAIRRKQGNGLDTSGSAIVSYEHGELQWGLRQLYEKTGNKTYYNYIVTGANNIVYDNGTVHGSYTISEYTLDPVRTGPTFLYLYQQTKQQKWKTAADTFKTQLNGHPRTAQGQFWHKKRYPNQGWLDGIYMGDVFYAQYTKDFQASNQTAWTDIVSQFSLMYQNTLQQPGAANYTGLLYHGYDYSHTAIWASSDRGHSPEIWDRALGWYLMALVDVLDIIPPSDAGRPKLLDILTTLAPRLRDAADPSSGVWWLVITQPGRAGNYFESSGSAMYVYALLKGVRQGYILDPDGSVVAAAKKAYQYMTSHWVVANADGTMSWTNTVQVGSLDGNADYAYYIGVPQVLNDLKGLAAFLLASLEYEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPS1</accession>
    <name>A0A9P6JPS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_853773</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPS1"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9528812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="20813" checksum="34936AA7138DD811" modified="2023-09-13" version="1">MSSAMKKRKIAVLGSRSVGKSSLVKQFIENHFMDSYYPTIESTFAKSVVYKGVEYDCHIIDTAGQDEFSPINSQYAIGIHGYVLVYSITSRNSFNMIQVVHDKIVDFCGLTKIPCVIVGSKSDLSMQRQVDSKDGEKLAKDNDCAWIESSAKNNVNVGKVFELCLQEIERNISPNQTEPPAKSCNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ34</accession>
    <name>A0A9P6JQ34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_767117</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ34"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="25"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="526" mass="56962" checksum="64E6926C88B8AE0F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQA7</accession>
    <name>A0A9P6JQA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_265454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQA7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="220" mass="24964" checksum="5235010EE5C96021" modified="2023-09-13" version="1">MMPRCRSRTALPKIAHGWKNPEVLKRYGVDVPSLVEDLGKAIEDVFKDMKDNFTLRSIEKESAFLQHLDVQLSDILDKIEGAFIKTFVAFRMKKDLVRQEPKLVRSPMRVFVLVSGKIMHRHPALMAFVLTNAFAILLEAALPPILVGLISRIGFGALGLQKSTTARSNQIKFYLKRKKIDLHRSLGTLAAKVQRIFYQAEVPKKALFGTFKRMGMKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRE2</accession>
    <name>A0A9P6JRE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_893059</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRE2"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07896">
        <property type="entry name" value="Adenylation_kDNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08041">
        <property type="entry name" value="OBF_kDNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029319">
        <property type="entry name" value="DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050326">
        <property type="entry name" value="NAD_dep_DNA_ligaseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006592">
        <property type="entry name" value="PRK09125.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810:SF1">
        <property type="entry name" value="DNA LIGASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14743">
        <property type="entry name" value="DNA_ligase_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="8">
        <location>
            <begin position="34"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="495" mass="54902" checksum="A2A1A57EBBC2DBBA" modified="2023-09-13" version="1">MEDELKEINGLKPKVWLEDGEEREVSSQSSNSVYKVKRTFDHYYCTCPAWRNQGGVPVNARSCKHLKSLLGDKYEDARVMMKNPDGPPPKGAKATKSKAAPKSKAAAKTPSKRKKKGEEEEEEEEEEVKPATRGRKAAPAKRKRTAHDEAEDAIDEDDEEEDVKPPPSKRGRKAAAPVSTKSKGKNVKKEEEEDDEEDENEEDDEEEEPAKGKSVPALLLANKWDLETGPDPAGWWISEKLDGIRTFYDGSRFISRLGNPFTPPQWFLDKLPIDVTLDGELFGGRGEFQSTVSVVKTVNSPHWKNITFQIFDIPSRETEPFEDRYDFLQKTFGQGGTHASEQIVVVQQEIAKSREHVLSKLKEVEALGGEGLMLRKAGSKYEGHRSGTLLKIKTFYDAEAIVTGYVAGKGRLKGSTGGLKCKMASGKTFNVGSGLSDKQRNKPPAIGTIIVYRFQELTRDKVPRFPTFVGVAADKTEPKDAEIPSTRVAGTSANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSM8</accession>
    <name>A0A9P6JSM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_891851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSM8"/>
    <dbReference type="OrthoDB" id="2367075at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="24497" checksum="2E8689C41A170FF6" modified="2023-09-13" version="1">MAFSSSDEDSIVNGMNSLSVDRHRSDIFVKVEDMTYPFPEDHFRRCNFQFVVEPGTNGNGTSQENPIILRAGLVSADDLDAVLEVFGLGISDHADDLINLSASKWFAALKLANLWQYEGLRRGALSYLRNKDEFQDDTINRIFYGIDVWDKSWVIEGCNYLVERAVRADSPVANQLGTTMYGVMIALYDVRGNLLINTGINLDANIKAILDIFVQGLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTM1</accession>
    <name>A0A9P6JTM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_758454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTM1"/>
    <dbReference type="OrthoDB" id="3266087at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13932" checksum="DA2D39664253FA3D" modified="2023-09-13" version="1">MRDPRKPAPVQNTPWTLSFPTQVQPGESRWSFDAWVARGGSPLHAWFFFVGFVLFPLWWVAAIVAVPRTRRLGGTDAEKGVILDDPQVEHDANSWRFRCRIMAGVSIFTYIPFIVLVAIYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTR1</accession>
    <name>A0A9P6JTR1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_785936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTR1"/>
    <dbReference type="OrthoDB" id="5595612at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1048" mass="113107" checksum="EA50777788DD3DD0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU92</accession>
    <name>A0A9P6JU92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_889756</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU92"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="13"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="34728" checksum="080DFFB2CD30365E" modified="2023-09-13" version="1">MTITTDLNAPLFTVVGATGSQGGSTVQALSASEKPYRVRAVTRDTNQLSAQKLAEIGCELVQADIDNSADVEKAFTASDFVFAMTKSDHAVIADEHKRGRILVDTAKAKGVKTFIWSSQLHLGRLSGGEMEVPMFDVKAEIADYARSISLNILEVCPGIFNKLWIEKCPPYKHEDGSYILSLPLNSNTKLPLIDIATDFGRYVVDAFEKNHTGRLLAAAEYLTLKEIAKVYSEVSGRQITFVPAEDEAFRRKLAENANESFVTNILNRLIAFRTIGYYGQNQDLDESNAILSTPAQTFSQFVHAHKSDLLKAMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWF6</accession>
    <name>A0A9P6JWF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWF6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="7063" checksum="9DBBD23FC8142689" modified="2023-09-13" version="1">MTISTCFPSLQMHRPPLSVRYSPTNQEPQVQPQTYSHFLEKYLSYFTTTPMRENLLPSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX40</accession>
    <name>A0A9P6JX40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L13e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_801733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX40"/>
    <dbReference type="OrthoDB" id="10264538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000003">
        <property type="entry name" value="60S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9535400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23912" checksum="16BF0B480B79B3AB" modified="2023-09-13" version="1">MGFAHNNVLHNNHFRKDWQRRVRTWFDQPGRKLRRRTARKAKASTLGVRPLTLLRPAVRGQTVRYNRKVREGRGFTHAELKEAGIGRKEARGVGIVVDHRRRNLSEEGKKINVERLQAYKTRLIVFPRKASKPKKGDSTGDDLKAATTRLALALPESIPAEAPRKITSTERDFKAYKTLRTNRANARFEGVRKARAAKKEEEEANKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX61</accession>
    <name>A0A9P6JX61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_841957</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX61"/>
    <dbReference type="OrthoDB" id="5581259at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28741" checksum="0B8BDEAC71D98EAF" modified="2023-09-13" version="1">MAPPPSYQHYVWASGHFLLLLSSLRYVLAFVTFKAASAWWYKASYTGALVSYAIVCNKSLGTPQPNIAYLRRAMLDENVQYLLLALFWWTSKPITITLLPYMIFSLFHALTFTRTTLISQFLPPSPPATAGGAPGPHPLAKKLQVWVKANYDPAMKIVAYTELVIFARVILGAITFRNSLLSPIIYAHFLRQRYYQSAFTREALALATKKIDAIVRKPGNPPILLNVWDKGQMVIQRWAGVTLAPNATVPEPAQTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC75</accession>
    <name>A0A9P6BC75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158125">
        <property type="protein sequence ID" value="KAF9521330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC75"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="29629" checksum="E4E83456F3635664" modified="2023-09-13" version="1">MDNTTLCPTEIVAQILSDSSFATLAIVGARISREMAKIFGENTISIMECVEELGAVIAGTVPLKVMDPDIMAGINPLVVFVLPKGKTQTLIDRLAMTGYIHLMPQQLNYAEKETVVQYIVAADAPHTIDRLKVFDDPAMLPEQVHLVESASLNPMFTVLSSPLSVLTSAISRNTIWCPYPKHLAERMCLVGPSSVRVLKPEPVRDGSIGVDGGSHTIDNRCRYKTRIWLGAPGVGQMLWNSEEKIDSDGLEKYDYRWNPAGLVNRICCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BCM5</accession>
    <name>A0A9P6BCM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_932678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158151">
        <property type="protein sequence ID" value="KAF9521292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BCM5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="38785" checksum="8CE7800E314A1948" modified="2023-09-13" version="1" fragment="single">MPKLSTTADVAAILEQIDDIIQRGVENDTLANAVNTIKPIYRETVDAKRQKHVQPLMQNGTAEQRKGFEEPRFFLGMLFRRADWKSSHQGNMDGYGESEKRELEAWRRTYQSKHPKGPGKEPAASGARTTQGAGPSKAAGPNMAAGPSKAAGPSKAAGPSKAAGPSKAAAFNAPAVQLAKGSKKVGEVDKRPTTKGQGLASKSAAAKATSAPVDGGLERTAGSPPVDPDTVHVKRKVPVTEAMDIDPPKSFQELDQESEGEGPGSRRGQSPGPRSTGGRSPRPSRKAKGKQKAAPIELEEDELMDEEEEENSKARTKSTGRKGRRSISKPKTKKGGNWRAREPPQHFKVKCSSCQDRNLPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BE18</accession>
    <name>A0A9P6BE18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158062">
        <property type="protein sequence ID" value="KAF9521446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BE18"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="28677" checksum="0A3DC635CE219D5C" modified="2023-09-13" version="1">MNNFELGSIPLFVPAHENVKLEEMEVEDLLSDVADEDEEEILEDIQVCEFEVFDTPETMDRRFPHGLPSDRTQRGNDIGATENPLAVSLPEDLLAELQDVLPICCVCEHPIVPTDEEFGNVLFKLSLCGHKLHLGCNCHLAQPFDIQGCFAPRASPSPEPALIIEQGGKEVNIYYTSISELEDADYVNPWVCPEEGCDTVYYSFLKDGVWNNRVTTRSRGSVMTYKGKAIGGVRTAYIVKPAIYRFEAPSFKGTTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3A1</accession>
    <name>A0A9P6E3A1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157998">
        <property type="protein sequence ID" value="KAF9521715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3A1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="25081" checksum="F56CE51D96176812" modified="2023-09-13" version="1">MLGDDGRDLSPITPIDEEDDPTLRIHVNHMHRIANDCGDLPAFNRDNKDRDPNMDKLFNDEPTTPFTTTGGDRQMVILDDGEIHLFPISNFRRSNIMEHALDHLPNSYPKPPPNKEGELIVDYIYHKEVVSGVVYYLVAWEGRDAGNSRWLKAQDLLNASSRIAEYEQWVHNKVRDERRERMIQMATEVIKRKEDARHRMESLERQTNQQHRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3G7</accession>
    <name>A0A9P6E3G7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157986">
        <property type="protein sequence ID" value="KAF9521826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3G7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="314" mass="35788" checksum="DFD2A68C576270D1" modified="2023-09-13" version="1">MFPGIKLWQVNQEFFIKYDEPYTGTIFGKQLASSTLGFSHWPRQLLLCLRVGKQGHNSELSEIGYLTPQWSKKLVCGDWNKKLNLERFKVTKFDQVFEEENQNQKRIPELKKNNGRERFGRRGPWYSCEISILSLMIEAWVTATISAACWLCNVAEIKEVEYGGIVAPGSNDQTFCFWDNAKLLQADKCKKHGGDLLAHSVRKSLRDTTFVAIWVRFFLSSSGKSCKLGSRQAWTFCHQQPVQLYSGFRRLYAQNSGSTKSVTSFSHGSTMATMICFCLERATSTEYEVITHAAYMLAVGTIPPIDPSQVEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3N0</accession>
    <name>A0A9P6E3N0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157972">
        <property type="protein sequence ID" value="KAF9521939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3N0"/>
    <dbReference type="OrthoDB" id="2523927at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="437"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="633" mass="72793" checksum="EDA2C909AE7D3508" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4U3</accession>
    <name>A0A9P6E4U3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ectomycorrhiza-regulated esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4U3"/>
    <dbReference type="OrthoDB" id="9988524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF53">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="181"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="290" mass="33121" checksum="930512941D3040A0" modified="2023-09-13" version="1">MSNSGRVSTRLVIPQPAEAHVNLIGMLEQLAPNQPTSGRKLALILHGTMGHRDYLFQKRLAMYLPIDSFRFDFRGNHESGGVWKQGNLLEDIEDLQVVVNFLKHNYDYVIELVVGHSRGSIIAFRWLTTSEDGRNVPAFVNASGRYRMSKILETPHGVAWEEDFTKQGYFTWNVTVARKQVSAKIRPEDLHKFVTWDTSFVWDRFPQETDVLSIHGLSDKTVPPYDALIYARALGDRSPGTHTLYLMEDADHNFSGRQEDVVAAITQWWDIRQRKELVTGVWVPGIKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E590</accession>
    <name>A0A9P6E590_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_740913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E590"/>
    <dbReference type="OrthoDB" id="2688210at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="168" mass="18621" checksum="4E76F97011144176" modified="2023-09-13" version="1" fragment="single">MPTLPHNPHNDTCPDYTAPVFQPARDQLTASNTNLSEALAAETLQNLWEATNIANKSLWDREIEDETAAAAVAAAAEAQEAREAEELELVKAREDADATLREDMKKNRAKYLTIRDRMVPTVLPMPASKSVVKKLANCQYFYLWHFTNAGLTDAAKTASSTKANRLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5W8</accession>
    <name>A0A9P6E5W8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_63944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5W8"/>
    <dbReference type="OrthoDB" id="3206554at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="167"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="36362" checksum="AFD1913E96D4CA01" modified="2023-09-13" version="1">MEPHLNIAKTFGALLLGGLFASFVSGFVTIQGVIYLRMYPTDAIGIKLLVLTVWLLDISHTTVIWSALWSYLIQNYGNESVMDIIHWNIAVTIVLTAVLTLLIHMFFAQRIFKLSKRNYWLTAPIVILACMRLVSACVTTSEMMHLKTFSRFIEQIRWIFTLGLALSSAVDILITASLVFLLQSNRTGMANLNAVIDSLIWYTFETSSLTTAGTVIAMLCWLVMPNNLIFMGLHFVIAKFYANSILVTLISRKKIRQGRAPSSSMEPVPVHLLDTRRPSNRGSDDDLAGQFEKEMAVRHSEQKTAHLQTTTVEINVERSVQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6A0</accession>
    <name>A0A9P6E6A0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6A0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6523" checksum="0425EA38EC3BC18E" modified="2023-09-13" version="1">MNIVYRPDHHNKQKCPKITAQRWALQVGRKINSANGRCTKRNVPCTLTADSELLTSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6A9</accession>
    <name>A0A9P6E6A9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6A9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="47472" checksum="24321106F24E78BB" modified="2023-09-13" version="1">MNGYSLVDYSGGTAFVGLSALRPTELTPFQFAAFADPLGEITLQQVSFTTAVIGTGIVFAHYAGLLDNNAVSKKPLGFTGWANLPAGYFPSKVDAHTDNGESCVLQSPFEAEYCIAEKSAMKWLKYPAGYFPQNVPAYNDNGIFSQLESTFQPEIVFCTLDDAPPPPKWFELYSEFVPSKMDPFVDDEVPFGSIDSPVCPFGSEKVERAFDLLRNPPTPVQLTRTTVQYTLDTPTATGFTQLLIIAVTAILSTAFSVMVFVIQAGPTQVEDFLEDKLVQESVNEEDPAQDVLEEHKEHTNEDQRDIAEVFSVEAEVVDLQGLDEVLRDLAEGDKGLDEGASEQESVLEVIESQVEAPAEQPVEEGFNSGEAISVPDTEIVTAFANSLFVEAEEITIPILQDVLKHIQTVEDRYVSFISPLLSSIINNELLVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6G0</accession>
    <name>A0A9P6E6G0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6G0"/>
    <dbReference type="OrthoDB" id="3233595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="32541" checksum="53C2F2C5C43BF58E" modified="2023-09-13" version="1">MNSYTRAKTVITPHMFKFKSAGAVTPTHTTSSPITTFAISQQLNLATLKIVASLGCGPLDTRITMPRMENFFSWGSRIHILADGTTNVVKHDIAVSNAGGRLKTCLRFTGGASSRQSTMHEESYANATRVLLTKKYIITNTIIHRNYNNSQCSIDVSILYDESTYYVVAGEVVHHNEGVEGYPIGERIVIANQFARLCGFSPVASENSSEYLKSKGFKVANFYADLNTSWNNELLRTALINNFTAWGWMRDGQLGPNSFEVLPDALKGIPGDLKWLESHQIPARNLVAHPHETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6N3</accession>
    <name>A0A9P6E6N3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_775169</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6N3"/>
    <dbReference type="OrthoDB" id="19092at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120104">
        <property type="term" value="C:mitotic actomyosin contractile ring, proximal layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="33"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="427"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="55391" checksum="A07B053E4C259837" modified="2023-09-13" version="1">MTDEEPIPLETSLDRFAHLRQPDGDPFNGRSSRDFCNSFWGPSDAGPSVLFTRMRGGSKTTNELHQFWSARRTIEEEYAAKLAKLSRVPVGVDEIGELRNSLDALRVETQRQAQDHDRLALNFGAVLECATADFLHIQTEHQQQVQMPLESRAEQKRIHELRVETAKGKYEGNYSQVQALNRQLGSDHLPVHEYRKVQQRLARIKQFMIANKLDHSLFTKTSKEFSQAWEAEWKDFCDSCQDLEIDRLNLMNDVMWAYANEISSVCVSDAQSIERIRDVIDQLVPDNDVRNFAEEYGTGNSFSMPANFNPSEDSVEQPTKPPIIHFIHNQCVSKPQYHLGQSNEDSPAILLSAPTVEIDSTEPQSPPIGQTPPTSAPATGRSLHQNSDVISPSSSSTSSRSLPRPPGKALFYGKNRLFSTFFITVINLLIPVKALYDYKATDDTEFDFQVGDIIAVMSTPEDGWWSGELLDEARREESRHIFPSNFVSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6U4</accession>
    <name>A0A9P6E6U4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">sterol 22-desaturase</fullName>
            <ecNumber evidence="6">1.14.19.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_862574</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.41" evidence="6"/>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6U4"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000249">
        <property type="term" value="F:C-22 sterol desaturase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11082">
        <property type="entry name" value="CYP61_CYP710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000021">
        <property type="entry name" value="Cytochrome P450 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="58949" checksum="E5214F531737267C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E724</accession>
    <name>A0A9P6E724_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CobW/HypB/UreG, nucleotide-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_877961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E724"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="1">
        <location>
            <begin position="5"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="34625" checksum="E6407F7777860E28" modified="2023-09-13" version="1">MSSIPITVFTGFLGAGKTTIILSLLKKLPKDFKVVLLKNEFGDVEVDSKLAQQSSLTAVSEILNGCMCCVLVGQMQNALIEIREKYHPDRIIIECSGSAFPATLAFQIRQLERDTNGHFNLDSIITVIDAENFVGYEDTSPTAKMQASYTDIILINKWEHVSERALDIVLDHLHTLNDETVKIKCQGKDGVDPGLIFGVQSKLFLSGQDSDFGATHDEVETLTIYREEDLALETLPQDSIWRAKGFVRLVDGTWISVNWAFGRCDIQEYTGGGIPGEVRLTLMGGRGSVRRPAIKFANLLGSFVGHESHYLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8U5</accession>
    <name>A0A9P6E8U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8U5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="53" mass="5994" checksum="4C61F64F9DAA5500" modified="2023-09-13" version="1">MSRCISRYSVTSLCDHIGLHRIHVWRTVQVPASCQHHNHGRTAGSSLSVVEPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8V0</accession>
    <name>A0A9P6E8V0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8V0"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="22721" checksum="4117D9197792E6C2" modified="2023-09-13" version="1">MGTGYLSCNERLMDLYIQQKRWNDAEKLGLLLISGGGSALSRITAFKVRQKAVRVIRINRWRRFAWDDDAKVYFLHQLYNSARQLAMVYVELKQYHKAQQLLEELLEEKMHGENPILVASKELLVTVYMESKEWEQGEKIQERIVQEMTERFGYDSEKLIPELNRLVNIYHQNNHLGKRHRVKLRLLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E964</accession>
    <name>A0A9P6E964_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ornithine cyclodeaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_877535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E964"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="42485" checksum="E49DBF55D381C8FF" modified="2023-09-13" version="1">MSLLVLTSDDVEAIICAFQSQNLQLIMAKVFSRFSLLEKKSYSDKSIDFLPDISMPERLSIATANHTALFMPARIGSHNPASLGDTAVKVVCVSKEGSSRGLPSSTLVINEETGSIKAIVNSRKLTAIRNAAGSLLSTCLMKCFQPQSIVAFGAGQQIEAHLDLHIQHFYSIKRCTIINRSRNNRALQLEKNIKTRFPHVECNLLAASSDSSDTARRTEALRSADLIICATSSATPLFSSDHVKTGTHIILIGSYTPQMQEVDGNLIRRALLSGTVLVDSKRDCLREAGELIGAGLTSKELTEIGDLIPTDLQGNIEMEKYEALMGGIPVEETPKDIERTFDGPVTIFKSVGLGIQDVAIASAVVEKALDQGKGISVAGYDRPASERGHISGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E985</accession>
    <name>A0A9P6E985_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860642</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E985"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12722" checksum="220BDD5B8031BB94" modified="2023-09-13" version="1">MLILRVKTMKMKALDYRRTVVNLSVVVLMVWSFRRSRHCQLRRLDQRKREKFDHVLFSASPSNGLTSPLSLSSIDPLSSHQLCHQHRDFSLIWNPPIPLLKWNTSRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9W7</accession>
    <name>A0A9P6E9W7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9W7"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056279">
        <property type="entry name" value="Aip3p_Bud6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23153">
        <property type="entry name" value="Aip3p_Bud6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="9"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="239" mass="27574" checksum="2D57EC2B9CE86A3E" modified="2023-09-13" version="1">MKITHAGTPKHLLELPMDILLEIFSYVYPTDLHTLARISKKVRNCLMNKKSKYIWRATFMNVDPPLPDTPEGMSEPAFAKMVFCEGCKKPVEMFSLTFLSSVLELYRFIYQWVQGEVQEKEIKDSYTKVLDIFKTIVLAFSKYRIDMQNSLSTSADLRTVLEEFLAQGASMANLQHYLPQVGMIVQKVLGDMKKGHERYELVHRENWQKQLGRHAWTPKQIYPSNPPNPSTAPEQAITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA55</accession>
    <name>A0A9P6EA55_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_772362</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA55"/>
    <dbReference type="OrthoDB" id="2983126at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00878">
        <property type="entry name" value="Arf_Arl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="121"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9525299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="195" mass="22301" checksum="7EB03C3D7C75DF1C" modified="2023-09-13" version="1">MSFAHHYTEIVMVGPDKSGTTSLLNRLKRKNVPKGVLPATIPTIGSNIETIRHERHTITIWEFGGQDKIRPLWRFYYWNAHAFIFVVDASAPERFAEAGEELSRMPKSRDIARFPLLILANKWDLVKDDTMDLERIRKELRVEELEKLGMVVGVMAASAMTGAGISEALDWVVERVSHELINSHNEDKKHVIQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA72</accession>
    <name>A0A9P6EA72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_897181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA72"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="27967" checksum="919BD0262EC6C950" modified="2023-09-13" version="1">MAQTVNQRINLLSDQPAIPIQLRTFEKETLPPVNGITMEDFNKTFEDWAQLHHLLSNTNISPTLAHALISSRTHFLAYEQLDKLIKEAVKTICKMEQRSEESLRLAKHFFDLATDRGLNEVEVIRGILLERKTQQNAQTTVIDEGDGRVETANRMDPPTYALTSDATGDVSTSTGNEPSTSRHRRRRNRNRNRNRSQNQQPVETGFYSPPPPPQFYGITGAGRRLTERNICRNCGIRGHYPNTCPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAU0</accession>
    <name>A0A9P6EAU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAU0"/>
    <dbReference type="OrthoDB" id="2720314at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="7782" checksum="449D784334728290" modified="2023-09-13" version="1">MAQDNSYRGVLTSDCEWLFILLNVNLDGEGDSYKLSRPFLTASVDSFTGKCINEDVSDMICGLLAHWVCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAX6</accession>
    <name>A0A9P6EAX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_771982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAX6"/>
    <dbReference type="OrthoDB" id="19928at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="36466" checksum="ED2CE612813164C5" modified="2023-09-13" version="1">MAFAPVSSNISQAINFLTLPLTLTQSADLVAAVKSVLRSTLPTALAQCNGQATLSFSPTSLPPRPVLAACIACDLVWSDWMTLLGNRDFDLIIEAHDVLVTYFDLSRPYTITVWSEPIPTPATRPLLARLNTFEPQVAISKLGQKTQRRTSLKLQATVNSAIARNQTRTVAQQLLDENHKQEADEIFEMISKTCILSPTPTRDAFPTLVIPSLTTAFPSPLSSPEVSSPSDSSSSRPSSRSSISSSEVSSQIFVDTEKKDKTKYLYQGGYTTVASGGVMLGGGPKPSATQAKRADIPSVPKYRAPIGSRNRFPAATPKNDFVASAQSWRRQATPPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB47</accession>
    <name>A0A9P6EB47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB47"/>
    <dbReference type="OrthoDB" id="3061359at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="692"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="948" mass="102283" checksum="F68E9583FC8CFE3E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB62</accession>
    <name>A0A9P6EB62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_501166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB62"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040414742" description="Nephrocystin 3-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="121"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="57344" checksum="24AFAFE9F5922674" modified="2023-09-13" version="1">MAVVLVILVFGADGSTHPCRREESSTTKNSFHIVLLLTIMSNPGHTSLFQDAQNLTFRDPTFNVTVNNHESRTSGVHSLSQMISKDAMYDSSARNPPPRCHAETRELSLDKVITFVDDPEPEKQVMWMNAPFGHGKSAVMQTVIETLIASGRKHRVAGAFFFGRDKEGRDKAHYLLPTILYQAAHNIPGMYEHVNNAINADPTLPSKSIEAQLIPLLVIPFQHCSPSSTHTPTVFIDGLDECYTIEAQRSVLKMISDAITVYRIPLRFVVASRPEAHLSDYFKKEPLHSTIRFFTLDDDFRSMWQYLREGFDEICNARADEMSEISAPWPSNATIYDLVRRASGQYLFAATTLRFVGDEYSNPLEQLQVILTLHPRCSSAFSEMDTLYTQILQGRPIHLRNCLLRVLGAIIVLQSISIAALGDLLDETLSNITTVLRGLRSVIEVDEPPISYPNFHKLLSPMLSLYHLSFTEFATDKARAGDFWIDKDAVEKGLIHRADFLLANSLSVTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBR9</accession>
    <name>A0A9P6EBR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBR9"/>
    <dbReference type="OrthoDB" id="3226519at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040230504" evidence="1">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="20520" checksum="E74C2A4DB2EB9DAD" modified="2023-09-13" version="1">MQLLSFLPAVLLALSVAASPVIDESFCPGAKVVSETYIGKDKNVKVQSLSCDTIVKAAPKEKVLLPRAANDLNVCGTHCNNNCFLPAGGGPDPNECHVISDALLYEGQNTGTLFQIQNGAVPGNPTVMQYRSCKTFFVNQDVQPLQFCRSQWAQIIDSLAFNCQATQNAHGGNCVADDQRWYIQVQSING</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECB7</accession>
    <name>A0A9P6ECB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="4">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_770206</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="4"/>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECB7"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000001">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000005">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002320">
        <property type="entry name" value="PRK01259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="14">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9526491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="317" mass="34333" checksum="4B1AA0AB364B532D" modified="2023-09-13" version="1">MLNGSGIKIFSGTSHPELAEIIARRIGLPLSKAEITKSGIGESNVTITESVREHDVYIITTGCGAVNTALMELCIMIHACKIASAKRITAVIPLFPYARQDKKDKSRAPITAKLVANMIQKSGCDHVITMDLHASQIQGFFDVPLFAEPSAILYIRTHFNVDDVVIVSPDAGGAKRATSIADRLGVEFALFHKERKKANEVSRMVLVGNVKDKIAILVDDMADTCGTLCLAARHLTEAGAVKVYGFVTHGILSGNALETVEASSLEKLIVTNTLPQQANQAKCKKIEVIDIGKVLGEVIRRSHYGESVSKLFHEVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED03</accession>
    <name>A0A9P6ED03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED03"/>
    <dbReference type="OrthoDB" id="3219649at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="280" mass="30305" checksum="16A9DBF2893F2497" modified="2023-09-13" version="1">MVTRAGVYGSILIQMCALDPFTKLAKRNVILLSGQSLFPDISALDDFTVILFLLDICQITRMRYPILTGRPPLACGSTPHSMSSQRGEPFWHRFGTKLFHKSCRYKRARFKSRDINSVYLLLRNKMKFATILISTFVATASASLLPRSGSPLTQAQAQSRLQAAGISATSSGGCTAKTNPSCTSYDGILSGTVDGVITLKGACGCAITITGGTETGHASGTYSHANGYKVDIRKDAGGIDTYVHNSFTKIANRGDGYPQWQSAAGNIYCDEGSHWDVLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED29</accession>
    <name>A0A9P6ED29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED29"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="29270" checksum="EDD71333101B4535" modified="2023-09-13" version="1">MANLKRLAEQVDCEPFTTTTSTTLPMSVSESIASLSFEHPAGPEETGTEIESQPLSGPRPPSIAELYDIKLAYPAVYLSPFEVFRAWRQTPTTLIIDNDEVQIENFFHNAQYRIEVEHFPDLQWPIRRGKAFAIPFLDICPERFRYIATNTQHMGQNRAYIRFALYRIDGTYVKKEDIIFSVLRQWNDTIYPRELALTAMIHSYPFSFGTYHPRIATFARAVLEDEGWDMNENFNSEDEEQEVDRHSESENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED38</accession>
    <name>A0A9P6ED38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_768956</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED38"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="467" mass="50186" checksum="4CCF7F00A0C979B9" modified="2023-09-13" version="1">MGIPLTHIDEVPPGERSSSINSSITPDRSDSSAKEHTEELEIGVQQNDTQKAKSWTAQIPTFPEGGLHAWLTVLGGTMVTFCTFGVVQSFGVYQDYYARIALPTRSPAQISLIGSLQVFFVFAIGLPAGRLFDAGYFRVCLAGGSLLYIFSSFMLSIAQPGHYYQFLLSQGIGMGIGMGFMFLPSLTITSHYFKVKRSLAMGIVIAGSSIGGIIYPILLNNVFSSSAGFGWGVRAVAFMDLGFLLTANCIMRTRLPPLKASQNAGGATFLMVVKDLPFMLYVLGAFLSFWGIFVPFFYLQVHASLHGVDPVFVRYAITIMNGASLFGRTLPNFLADYIGPLNVMGPSAFISASLIFGMFGASDIAGVTTFAIFYGFFSGGVVSISAPAVGSFITHPDLSDFGIRIGILSFALAFALLTGNPIAGALLTSNHIWYRPLIFAAVVVFAGSACFALIWKSVSTRRKSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EED4</accession>
    <name>A0A9P6EED4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_389699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EED4"/>
    <dbReference type="OrthoDB" id="3361907at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="161" mass="17358" checksum="CF198C1962A0029F" modified="2023-09-13" version="1">MNAVGKAQQTTTETSLAAQGDRSVGHLQKRVIPLIILGLIGLLVIASFATMMGEMEKKSRQTAGELLDYLDITFWDRGGGKPEPTCSAYMYYSSSCAALGNSWSSHCSEGGEKVYDESCRGLFTDGAKACGFLGCSSLCMCSLMTMQIKEAETCFIGYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEP3</accession>
    <name>A0A9P6EEP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_854977</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEP3"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000407">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="15"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="406"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="452"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9528143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="686" mass="76713" checksum="F3A229C6FC6A9701" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEQ4</accession>
    <name>A0A9P6EEQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_855849</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEQ4"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="30"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="42679" checksum="C81451478A8AF35E" modified="2023-09-13" version="1">MSFFTPAPEPPTKLGRYRVLSPHAGVHVSPLVLGAMSVGDQWDKIGLGAMNKEDSFKLLDAYYDKGGNFIDTANNYQDETSEKFIGEWAEKRGIRDQLFIATKYTMGYKRASTLGQKIMYAGNNAKSLHISVEESLQKLRTSYIDLLYMHWWDWDTSIEEVMRSLHTLVLARKVLYLGVSDTPAWVVAKANQYARDHALSPFVIYQGSWNVMDRAFEREIIPMARSEGLALAPWNVVGGGKFRTDEEEEKRRQTGEKGRTSFGLDWERNEKEKAVSKALEKVAGEVGVKHITAVAIAYVMQKATYVFPIIGGRKVEHLEANIEALSISLSEEQIKYLESATEFEPGFPVSMIGDGSSPSIFLGLSGRLDPKPEAKPLRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFA5</accession>
    <name>A0A9P6EFA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFA5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="11110" checksum="175F3BAFE092BB5B" modified="2023-09-13" version="1">MLSDYDSSRKEETETLLHEDGALSQSAPSNKNSEFSYTLYAFLLIAVVINSALLIYSLRIQTQTRALLSLPIDLQHLNKPDPFVGLSTKLSKTTVNMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFB0</accession>
    <name>A0A9P6EFB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFB0"/>
    <dbReference type="OrthoDB" id="3174721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9535" checksum="B5174C9033B3A36F" modified="2023-09-13" version="1">MSNPSEPLVLTWQPEPPPILPDEHPPDYSSASRPTINVRYIFSPIAGQNAMLVVPPAESPDTRPKFYIALSTNIFMPFSYITTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFL9</accession>
    <name>A0A9P6EFL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="14">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_813572</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="14"/>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFL9"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF12">
        <property type="entry name" value="EXO-POLYGALACTURONASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="active site" evidence="16">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9528653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="393" mass="42142" checksum="F600FA0EFF5EEEB9" modified="2023-09-13" version="1">MVFNLPGRLFLISAAQIASPSCTLSAKGSGVDDAPSFLSSVHSPSCPTITIPSGITLNIASRLDMTGLKDKQIVLQGKIKFNPNITYWSQNAFTIPFQTQVTFWLLGGQNISLSGGGTIDGSGQAWYDAYANNNSLPRPIILSLYQAKDVTIENISMLNGPEWNNLVNEAQNVLYSNITISALSTSKNSASNSDGWNTYRSDNVTIRDSTIVNGDDCVAFKPNSTNIVVKNLDCTGSHGISVGSLGQYPGTYDIVQNIYIKNIKMSKAQNGARIKAWAGPNVGSGIVKNITFENFVESAVDNPVVIDQCYMTTAAVCTQNPSNTYIQDIWFKNITGTGTKSTVASLSCSPDGRCSNVHVDDINLKYPSGSAKYTCQNVNLTGNSASLFICTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFT0</accession>
    <name>A0A9P6EFT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_356481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFT0"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0041">Annexin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="58561" checksum="8CF955E41E55FC80" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGL3</accession>
    <name>A0A9P6EGL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Recombination protein Rad52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_766355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGL3"/>
    <dbReference type="OrthoDB" id="206565at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.80:FF:000001">
        <property type="entry name" value="DNA repair protein RAD52 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="22203" checksum="38F4595CD7F5BC4E" modified="2023-09-13" version="1">MHGTQLAQQSFSLFGSQSSFANDTISEETAKKIATLQVKLNRKLGPEYISQRPGPGGGPKLTYVEGWKVINLANEVFGFNGWSSSIVNLTTDFLDCNEETRRFTVGVTAIIRVTLRDGVFHEDVGYGMLENGKGKGAALDKCKKEAVTDGLKRALRNFGNVLGNCLYDKSYTAEIVKIKVEQVSLIVYPKPKSMLLYLTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGW1</accession>
    <name>A0A9P6EGW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_812181</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGW1"/>
    <dbReference type="OrthoDB" id="1847590at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.310:FF:000001">
        <property type="entry name" value="NSA2, ribosome biogenesis homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="260" mass="29400" checksum="CCB3B5E495BAB00B" modified="2023-09-13" version="1">MFQNEYIEEHIKRHGRRLDYFEKKRKREAREVHKSSAVAQKAFGIKAKLLHAKRHAQKIQMKKTLKAHDERNIKQPDSGSVPEGALPTYLLDREGQKDAKAMSSAIKQKRKEKAAKYAVPLPKVRGIAEDEMFKVIKTGKSKSKAWKRMVTKATFVGEGFTRKPVKMERFIRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGLVTAGGKVVFGKYAQITNNPENDGCINAVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHN6</accession>
    <name>A0A9P6EHN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="1">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_275750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QNG1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="1"/>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHN6"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF1">
        <property type="entry name" value="QUEUOSINE SALVAGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="405" mass="44621" checksum="8359D033D8CE756C" modified="2023-09-13" version="1">MPALPPSGQYLVNIRQSCRNLRVASGILIEPETIKRLLISPAFTTSFERVSKDHGLLLPLKFASHLEELNFISILSLLNFASGFRVPLHTQTGRGAWDSIRALCFSLFITSTTEGDLLSAKGLQTLSTAKISELMRINLHVEKPHAKIPGVVVGELGGPLFELVTMIVDVLKETGEILEKSGYSNLGAFVVEALQEGKKVQNTSDDAAVEVILERLATAFPAFRDVYEIDRQPVYCFKKALFLVHAIHVRFGSMSPLPFPVPNTENIPVFSDNVLPSLLIHLGVINLPTNSPLSRLFPSAAPQQLDSLLGPAPPQVSKIPETVPKEGSVVTIEQSYILRAAAVDACELIVETAHGLDHSLLQEEDKRGISKLSLPDLDMWLWAVAKDRPDYRALERFVDQNSIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHT5</accession>
    <name>A0A9P6EHT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein YAE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein yae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_928077</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YAE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHT5"/>
    <dbReference type="OrthoDB" id="20086at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038881">
        <property type="entry name" value="Yae1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829:SF0">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="9">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="197" mass="22250" checksum="CEAC3434991AA7BB" modified="2023-09-13" version="1">MYSPWDDDHSGQNTQHQEAEWTKLSNDFTNAGYREGITAGKESALQEGFDTGYADVGAPIGRELGILRGMATVTLNLLDGQSKMLQNVPEDKDKLLAEARDISTQLSRIRFSDIMPPDLEAEAHAREHLQIQGEELDVHHDVQNKKDIETLEDRLENLNREEDSQFQGLRPTAESTKELRERLYTVIKRLGLGATFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHV5</accession>
    <name>A0A9P6EHV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Stress response protein NST1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_853296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May act as a negative regulator of salt tolerance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHV5"/>
    <dbReference type="OrthoDB" id="21629at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025279">
        <property type="entry name" value="NST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40240">
        <property type="entry name" value="PLEXUS, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40240:SF1">
        <property type="entry name" value="PLEXUS, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13945">
        <property type="entry name" value="NST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="193"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="379"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="475"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="865"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1019"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="263"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="537"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="670"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="739"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="910"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="937"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1031"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1126"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU049441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1135" mass="122831" checksum="9A220DAF66BFBA96" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHV9</accession>
    <name>A0A9P6EHV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_882599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHV9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="36126" checksum="6F3242B99599395E" modified="2023-09-13" version="1">MGWSNMVEYRCGCQTQLSFQLGLKPTCLFVHSYALLVQKSQSYLVGISVLRSLPATTTPTSTSQLTLPTRVGHATYGFTEAPYLELVQTIASKYKHRHDHAHKSSGLNIQPLRSPQVRIHAYTIYTLRLWPTTSSQSAPQPPTPLLIESYMLRLGLDSSSSSISAIKWPDLSSFIASSHWKNSNPATISILILLPSRIESVSLGLNSDERLGVVLVVLEVRDTLGESSVGDRFISPGSLTLNNFDLNFNFSYNYNLNRFPNIRGQRRPSFPAFLAIDLGPHHPSFAPLLFDIPRSVPGTTNANARIRFGIRTASSRIERSQVRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI96</accession>
    <name>A0A9P6EI96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_187239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI96"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="298" mass="33708" checksum="B6551CB93EE99F65" modified="2023-09-13" version="1">MIAKHSQVREASLALLNPRGNLGTTALDPFILPLPVVSYSVLVACEGEASETLEVLNMAALENFQFEATAVCRFTADAVTFFENYDSDEEEPLLAFDFSVVADIFGRLTSLILTRVSFTKEDCQELFASTPLIKSLRLFVTSRCNSRNPKHPFKFIVYHPKAMNEDFMDLFSDLPAEDNIRSNNFILPRLEDLHLFHPCHINDGKLLKQAKRYNKLIKTRAGLSAKSQSHLLSRSGSDVADQPSFQFTLSFSEEHNMRADIPLVMRELNGTAEKLRHVCIVDVGYKIVDTFEWRPEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIF0</accession>
    <name>A0A9P6EIF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_906130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIF0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="26706" checksum="FD628F9A3134D9A6" modified="2023-09-13" version="1">MRVPDSSLRLHIFSGEISRYRSVVFTILAATLGLGLNVSPDWNWFDPLNLDRPPSGDAQLTDAVVEDFVPASISTSTNVNVRCPQSCSSKLERCTASCKRQDHPGTRVAITLKTNMKTLSRSNQARAQARAESHMNGAVAYSECMDSGSGSASRTNVEAGGVYRVASTRNKGVNEVVPGGGVTCVAVCASMRARVASTTTCSDDSFPETTLTFFAHNWPLSLLNVECRTRFVAYRHLGTRSFDLAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJF6</accession>
    <name>A0A9P6EJF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_905452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJF6"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="56184" checksum="0877367FFB4D8E1D" modified="2023-09-13" version="1">MPLEDLPNEVIAEIFVGCLPQSGSYHLADPKKAPLLLTRICSPWRSLAHETPHLWTNLWLEPQLPSSPDRPARSQDECIDQYRHWRRHAAQSLPFDLRLSLASLKHLDVDPSAFWLPLVSTIAENTSNLRNLFIITPEFEYCNLLWRLPNSMPMLETLYIYSRSANEIKTNDVRSIQAFSQAPALRIAILDYRPDRRELIALPWAQLSHLAVSFPITDTKFRNLLGSCLNLQELTVILDRRVIISDQTPARDIHTNLRRLDITFDIHVGQPSPAIFLLVQFSALHSLAFRNVTVNGGQHFQWLQDSPAREHLLRQFYNLRRLKLGFQRLSCEILLEIFKVAPQIVELALDTHIVNYVQLLDTLTYVPSTDQRVFLPHLENFQLYIEVAFEISPGADIPFSVESFISMITSRSKSFLVKQPPPFELVPLKQVYLCIEDRDLDQWLDVEELTTRADSLAETDNMYVEVAFSQHKEEWLEQEVGIWEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJF8</accession>
    <name>A0A9P6EJF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_745206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJF8"/>
    <dbReference type="OrthoDB" id="2272314at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="22019" checksum="5C14429244660676" modified="2023-09-13" version="1" fragment="single">RRRADIYAIAPARQPFDPAWPTHNLGRMDVSCRHCGAMHWMDERLTSSTNANPQFGKCCLSGKVSLARLHNPPNELDSLLRGDDPESKSFRDNIRRYNNALAMTSLGCTVDHSVNQGQGPYIFKVQGRLSHLSGSLLPEPDVDPVYAQLYIYDPADALQARLANPINRDLSRGTMQKLQDMLFRLHPGAEMYKNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJN6</accession>
    <name>A0A9P6EJN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="8">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_763813</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="8"/>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJN6"/>
    <dbReference type="OrthoDB" id="6335297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03793">
        <property type="entry name" value="GT3_GSY2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000014">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000045">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="739" mass="83823" checksum="DE27594DB33C76C8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKC7</accession>
    <name>A0A9P6EKC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_834413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKC7"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="611" mass="67417" checksum="2EEBC44F39417663" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKY3</accession>
    <name>A0A9P6EKY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_881947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKY3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040417811" evidence="2">
        <location>
            <begin position="21"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="22925" checksum="E0EC5BDFE5E49F79" modified="2023-09-13" version="1">MVLKAALILTALAFAIGSCARPLPMVFGEGSPQVVKEWGNDNAGLHARFIKDLLIQHATKYVSNKLGTNLQVGNDQHPNKIHEYDEHAEEVDHNDNHNRQRHEDHRDLPSNHENHRDAHNGGHEAQQDVHRDQHQQPPHHHPDNPPFHPAHGHSGPAVVYVFHPPAGHSYYPPSSPPHPLPPHYMLPPPHYPRPPHPHGLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELK0</accession>
    <name>A0A9P6ELK0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELK0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="14766" checksum="AE132151FF0DFD36" modified="2023-09-13" version="1">MCSFAFPPSFNINTIADAFDSVQYLLCVLLTLHQSTAAGVSAPSQWLVAAVTSSLTGVTFHAQAFSSRFLHTQDASAPQFPCPWTSQHCFKETSPSVSASKSSTISGSAQHNLRHHSTSLWTWKTETTQLSEEDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN22</accession>
    <name>A0A9P6EN22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN22"/>
    <dbReference type="OrthoDB" id="3249986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="37968" checksum="E8D8AB27356CC066" modified="2023-09-13" version="1">MPSSAPSITTSKSTLMHACLASVSPEILTLDSIIRATPRVSLPHKVALPTEILLLIREWLFPDITRILIQHSTAALEAYEHSLRNLLCPDCIAYNLDIFGPNIWHWEHFNGPCACLEVDNISCVGHGPHNPQNLKAATSLPPMPNPNEYMNAQEWLESHLSREAVSRLKSQSPRIPRMTPTLQFPQIWELVSLILEEFGCHFLPDPEDPGEGKPIPAGPESHPPRRHDLVQVISSTTTSTLSTGSECYVRDPTLLHRAARDLCLEWTEPFGIHDRDTSSFKGQLWRPNRGEAHQDREQVQLLFSVLAAGAAACLSLPITFTTVAITIVCFYSKPRSFRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN47</accession>
    <name>A0A9P6EN47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_848518</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN47"/>
    <dbReference type="OrthoDB" id="10251371at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="13">
        <location>
            <begin position="221"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9531654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="358" mass="40150" checksum="57A4F629E29D61C1" modified="2023-09-13" version="1">MSTTRSRTSLFLSYRDSQAPRRRRTRTTAYESTEYHDDENEHLIQASSHVSVDIPSLPPKWVDISDQVEEVIANVQAKIQTLDKLHAKHVLPGFADRSQEERDIESLTTGITKDFRTCQSLIQRISSQPHAFPPDPQKSNHETLAGKNVQRGLAAKVQDLSATFRKKQRVYMEKLSGHAAKNQDLLVASGAIHLKGSDGLSAVDDDIQAVTQQSLVHADPSHELASRDRELSEIAKSIASLAELFKDLSVLVIDQGTLLDSVEYNIEQTAVQMEDAVTELKIATRYQKNTGKRKCIFLLLLIIFGLIFILIFKPKRHHTTPPPPQPSTVIPRSSIPLLSENTFTIPIPRTRPYPIVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP96</accession>
    <name>A0A9P6EP96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP96"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18491" checksum="32C33AD048ADA275" modified="2023-09-13" version="1">MFLRRQSIEYWMTIFLIVNRGTLRVDLRKANEFFYCFIGVSRIASMTAILFCSNVPKSANMSGNSTDCDYHLGSITSPFGNVSDKLVFRRRDYEEREVSIFAWVERSHSPGRILHKEVIAGNSTVSRTSFFAFLLGRYTSRTLANSSSLVWVPEIVAPLWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPJ0</accession>
    <name>A0A9P6EPJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_806774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPJ0"/>
    <dbReference type="OrthoDB" id="3257538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="39231" checksum="C118EC07CF0A1839" modified="2023-09-13" version="1">MYLQVFRFSPQISRRNLPVYLARQKLFSSSSNSAVLTDDELKNLDAWTVSHQTVTSHDPLTAEQVHDLFITMPTRDGGRLPFEAPVAGQPLPHGYHLPFFHAKRPSYELREDGTENDHSPPSPFLTRMWVGGSMTWNNELPLKIGIKTKASSRVQDTKMRGVEAGNPKLFARKAIQYVQEGQTVPSLTEERTHVYLHSGIYAKAAKIFDRPVQVPNGPIAFSFKFSTSPVSLFRYSAIMFNAHLIHYDPEYSQKVEGYPERLVHGPLTAQMLLDVTKLQMPGLALRSFDYRATNPFFVNQEATIFGHINESEDMVEVWCQDNASKAVVMTGKVHYTADESNLEVKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPM0</accession>
    <name>A0A9P6EPM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_846318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPM0"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="31802" checksum="F3075BC906ACB576" modified="2023-09-13" version="1">MAGGIWFITGATSGFGKRFAVLALSRGERVIATGRSLVKLQALVSSLKPEFLEHIRTEQLDVTAGAHEVKVVVDRAAKHWGGIDVLVNNAGIGYPGLTEEGGTKLLRRQFEANLFGVADVSTAALPYLRQSKNGRLVVVGSRSAWSAGKFGIGPYAASKAAVNTLAENLMFELAPFNIKVLLVLPGAFHTEGINDQKFFTENPISVYDETRAASIKFFSSINGKQPSDPDKGAEVVVDVIQEQGIAEGRPWPYYLVLGEDAEADIRSKCNKLLANLDEWAGVTRSVKIDRQTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPN6</accession>
    <name>A0A9P6EPN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C-1-tetrahydrofolate synthase, cytoplasmic</fullName>
            <ecNumber evidence="8">1.5.1.5</ecNumber>
            <ecNumber evidence="7">3.5.4.9</ecNumber>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CPB83DRAFT_591925</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="7"/>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPN6"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009257">
        <property type="term" value="P:10-formyltetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.770:FF:000001">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1510.10">
        <property type="entry name" value="Domain 2, N(10)-formyltetrahydrofolate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="20">
        <location>
            <begin position="34"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="21">
        <location>
            <begin position="174"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF9532986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="969" mass="103878" checksum="149E8A6CEB307583" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ28</accession>
    <name>A0A9P6EQ28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ28"/>
    <dbReference type="OrthoDB" id="3066754at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="614"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="721" mass="78034" checksum="D59870E22D1372A9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQA1</accession>
    <name>A0A9P6EQA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein NSA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_846612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NSA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQA1"/>
    <dbReference type="OrthoDB" id="18388at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037379">
        <property type="entry name" value="WDR74/Nsa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038">
        <property type="entry name" value="NOP SEVEN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038:SF4">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="43246" checksum="B1E371753A7E38E2" modified="2023-09-13" version="1">MTRFLIGDELGNVKVLRYIPDVSADQKMELKFLHAHNKSAPARSVQRLTAKKAGNLMMLASSFSDGECSLAALSEDDELSIGCSWQEKRMKGSKFVGTSITESAVTTCTASGMLSRTSFNVEDGITISEHTTGTLPSRLFDWRQSPDGATFCYGGDEVDMSVWDAERTFHNLSDAASASTTPGSKKRKRNDDLFPAEIWRARNLPNDHLGLRQPVRISALAYLDSSANSHHLVAGTQFGDVRRYDTKSGRRPVSHWKGIAKVAGVKVVEKGFSEHEIFVADGGSSLYAVDVRTGGILNGYKGISGAVTSIASSPTFMASTSLDRFGRIHSTIAPPAKAGAHQEKRGEVLDKIFMNTTPTVVVWDQCTTATKNKLQPNEEVSEDDEEDTWNQMENIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQC7</accession>
    <name>A0A9P6EQC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 18">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 18">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CPB83DRAFT_845914</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 21">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 18"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQC7"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 18" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="23">
        <location>
            <begin position="172"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="516"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="552"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="19">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="19">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF9533144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="603" mass="68506" checksum="4019C8E3C2252294" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA0</accession>
    <name>A0A9P6ERA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_880201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA0"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="39443" checksum="8C4FF4CD43E0E5B0" modified="2023-09-13" version="1">MIFARGQDNSQLPNPYAPEAWIPSTLAEIFRLHHCLGVGCMSIFLWDVLSSLVQDYIVVFRRKFTFQTAVFLTIRIATFLFLLGSAFVFMTDLDDCLPWSIVNSIGYITTHCATGLLFYFRVAAVYRGNPYIINFFRICWLSLVAGTIMGPATVTYIHIPPTRTCVIQVLPSKAQYPVVAALAQGFYDLLVCGFITYKLSSGKETESRSGTMGRRATRSWLGWKQKTAMFTRRFLQDSQLYFLLIACVKIPEIICFFAFQGSTYGSLAQLMLSFLDTVVVSILATKVYRKLKLGQPGLLDQASSHTQNISFLRKDTSGGTHLNSSNSGTQVTHGTSGSNKKSSRHSYPPVQSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA8</accession>
    <name>A0A9P6ERA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SRR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_845366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA8"/>
    <dbReference type="OrthoDB" id="551431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012942">
        <property type="entry name" value="SRR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040044">
        <property type="entry name" value="SRR1L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28626">
        <property type="entry name" value="SRR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28626:SF3">
        <property type="entry name" value="SRR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="3">
        <location>
            <begin position="97"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="31405" checksum="1B97586F824A5C27" modified="2023-09-13" version="1">MTDRSRNNKPASSLPPPTASGSFTYSDFTTRKKKRNNKHQVSRTAPQTLSSSLPPLREKLLGEGEWFANCSRILSDAWKEFCATTTPTEQEPSTKCKSDVVGLLCLGLGSPSASLNARVQLAFLTEACKILDIALDLGLIYDPVFAEEDIAYFKTLQMKVLEPSDHTNDAHLNLNGPMVCFMPHCDMELYEALLRVNAGDKSQDSGKRSDNESSLENVFLIGNSLQAYLDNKPSSVLKTKSPNLLQFGERHSFTSLLFYLCFRHRNSSKYLLLLKNSPNTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERM0</accession>
    <name>A0A9P6ERM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIP41-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERM0"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="36116" checksum="B4E0D4DEA1A6B75B" modified="2023-09-13" version="1">MSPPQIPKHTLQESPTTRSITVSNWTITSSTHPISNAPQCDALHASLGGNLPLPEMTFGQNYLSLLHRPTGKAWAFTTDEALRCVKTGELSEGDGPVKVGYADKWLQSRTGEGSMMPMPEVVATKPYDWTYTTTYTGHETQLEADTDISSIVEPRPINEAQRKFKWVDADPEERSQSIPLAELSRPDPILFYAEIPLFEDELHDNGSSSLLVRIRVMPTCFFLLSRFTLRVDNVLFRTFDTRIYHSFSFESPPILVRELGGWEAPYDHVQRHLPKRDDLTPLTDPTFIAKVLTEMSKRISQREGAKTGWRGLGSRAQVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESD0</accession>
    <name>A0A9P6ESD0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4219 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_756619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESD0"/>
    <dbReference type="OrthoDB" id="3265539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11808" checksum="3096F7B5AB70473A" modified="2023-09-13" version="1" fragment="single">MGKTRFDKLTDENYHEWKFFMTACLTKKALLEVVDGSKTRPSGPPNALRAFDRKQAEAEWHICMSTEARAEIILNVSKTQLSHCRADDPKVIWDNLTIVHGCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU76</accession>
    <name>A0A9P6EU76_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_781046</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2</text>
            <dbReference type="Rhea" id="RHEA:23916"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="EC" id="4.1.1.35"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="6"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU76"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000150">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="18">
        <location>
            <begin position="102"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9535015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="421" mass="47735" checksum="75057EF0F092893C" modified="2023-09-13" version="1">MSSAPTKIHTVDKEGKEITTVGFNRFGFDSEVNLEALRALYLRAHYSNAGPNGKSAQNSSDEDGTYQSNSIYNKETGGISYTTLTRFPPVKLLAPSERKRVLVTGGAGFVGSHLVDRLMLLGHEVTVLDNFFTGSKTTVSHWVGHPNFELVRHDVVEPFMIECDQIYHLACPASPPHYQYNPVKTVKTSFMGTLNMLGLAKRTKARFLITSTSEVYGDPEVHPQHEEYWGHVNPIGIRACYDEGKRVAETLTYGYQRQDKVDVRVARIFNTYGPRMNPYDGRVVSNFIVQALKGEDMTVYGDGKQTRSFQYVHDLIDGLIALMNSDESRPVNIGNGDEFTIIEFAELVREIVEKVQDEAGIKRTRSVKIIHKDMPKDDPKQRRPDTTRAKETLKWQPRWSVRMGLEEMVRYYKAKMEEGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI61</accession>
    <name>A0A9P6JI61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_865240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157989">
        <property type="protein sequence ID" value="KAF9521794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI61"/>
    <dbReference type="OrthoDB" id="4505683at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040170117" description="CFEM domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="7">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9521794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="15730" checksum="60A9E5E34CC54D4C" modified="2023-09-13" version="1">MFSKIFVILAITAATVNAQSSSATTPVPSTVAGVSPCILGCVLPAAAQNGCTSVLDTACICGSAQFQADAAQCLATNCPNDVDSALQLQKAQCASASVTPTGSATPRPVSFSSSPSTPTASGSASGSGSHTSSGAPSATSSGAASMVEGSVVGVLGAIIAGAFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIM6</accession>
    <name>A0A9P6JIM6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_878318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIM6"/>
    <dbReference type="OrthoDB" id="437457at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="292" mass="32535" checksum="6725E32D32716734" modified="2023-09-13" version="1">MAFVVDLFHAMTGRVRAWKSGTHPARSRSSLVDQVRKGRMRSSFTQFTHGPTANGSNSPHIKRAKVQTLVFDNKPTWRHNYFILQLNNMHAVPAINHPCTLCCRPTSLWCSRCQSAWYCSPEHISSDWPRHRRECVPAGHDQGSYNVNMIATPPPAEPQLVTVSAILFSPEDERPRITTINCKPSPKASQGMCPTPILDAFFDDQPVQSIVLTQGLNGEPLRFPLHLWYAPNLLNKGSPVNRAIFHITSGAADKPWAGPVVVLKHNGSRRQGYSDAGSNDLPALSAYFLSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIN6</accession>
    <name>A0A9P6JIN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Allantoate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_777543</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIN6"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF59">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="542" mass="60785" checksum="88B2C3FE8A49F2C9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ38</accession>
    <name>A0A9P6JJ38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mus7/MMS22 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2386201at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035361">
        <property type="term" value="C:Cul8-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019021">
        <property type="entry name" value="Mms22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28122:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09462">
        <property type="entry name" value="Mus7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="710"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1986"/>
            <end position="2007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="869"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="880"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2051" mass="231627" checksum="24C408DE9197ED70" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJA6</accession>
    <name>A0A9P6JJA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_776476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJA6"/>
    <dbReference type="OrthoDB" id="3016366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="170" mass="18764" checksum="9B84FE5526FFAB8F" modified="2023-09-13" version="1">MLFDQLIVYFSFSTGQIFATAFATAVKAKSFHYTLSIMQDTNIAMKIHVKEPAPDHFVFEASKQTLKASRTLCCALLIGHLGNHTIEEVITLLKEIPLTLPDIDKDVDVRFRCRVFLKQCIRTLSSAGIVNCKDANAVVNGELRELAIKQSEAILTGTGAYIIAQSQISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK05</accession>
    <name>A0A9P6JK05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_690853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK05"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="52" mass="6441" checksum="967EAB23A67E0426" modified="2023-09-13" version="1">MYQQFHPRNLAFRHSLEAIRDSFQPIRYYFIVVWLNNFHHSFTFLGRPSQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK65</accession>
    <name>A0A9P6JK65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_687081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK65"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="391" mass="43735" checksum="398171F251780BFF" modified="2023-09-13" version="1">MSFFTPVSEPATKLGRYRVLSPHAGVHVSPLALGAMNIGDQWDKIGMGSMSKEDSFKLLDAYYDKGGNFIDTANNYQDETSEKFIGEWAENRGIRDQLFIATKYTAQYKRATPLAQKIMYAGNNAKSLHLSVHDSLKKLRTSYIDLLYVHLWDWDTSIEEIMRSLHALVQAGKVIYLGISDTPAWVVAKANQYARDHALSPFVIYQGWWNVMDRSFERDIIPMARSEGLALAPWNVVGGGKFRTDEEEERRRQTGEHGRTTFNPAWERNDREKAASKALEKVAVEVGVKHVTAVAIAYVLQKAPFVFPIIGGRKVEHLEANIEALSISLTDEQIKFLESATEFDLGFPLTMIGDGAAPSPWLTLSAHLDPKPEVKAIRPVTNGDKNAVIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL17</accession>
    <name>A0A9P6JL17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_618900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL17"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="11472" checksum="DEB12A30B08B0F39" modified="2023-09-13" version="1">MHYTTIPPPSLLVFSCLSLPPPTIHTMKNENEAEGRGGLARQVCFKIKYVKVVPMINHASYKFSCTYIGPSYIAFISSLDSMLRCALGLFSFSFKIVMCGSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLY8</accession>
    <name>A0A9P6JLY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Paired amphipathic helix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_896789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLY8"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12202" checksum="109C7B8C446BD98E" modified="2023-09-13" version="1">MLHLNRDEAVSFVDNVRYSFEQDPGKYDRFLDIMKDLKANVIDPGDVIVQIAALFNGHPSLAREFNAFLPPGYRLHPTGEGPSSCIILYTPEGNTVYPRDYARRGSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM97</accession>
    <name>A0A9P6JM97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_885554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM97"/>
    <dbReference type="OrthoDB" id="4590707at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="22957" checksum="5328F0DB6CBE3892" modified="2023-09-13" version="1">MSARLARSAFHNAARRAQTTIGSSLPRMSRRMASTASHGAAKSDTPWIVGSLLIFGPAFLYLVSPTARKTEHHIDHKDKHEHPALLNDEHSKVLEDKAEKAEKPKPEVVQDDEGTPADVSSSVAVAQFKQSTDSPKEGQSAEKHESLKAAAESEGSKEPEQPVAEKPTSESSGNKDEKSGTFREEGDSSPTDLGKARDAAKEGVPPKKVAEGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMV4</accession>
    <name>A0A9P6JMV4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMV4"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="9293" checksum="16E6CD1222525A2B" modified="2023-09-13" version="1">MDRIPPELHERIISELKHEIDALKQLSLTNSDLTAICQRHLLREIRVGQTLAYLEFTNEGNVEIYDGLSTSYATALLPTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN24</accession>
    <name>A0A9P6JN24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_884493</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN24"/>
    <dbReference type="OrthoDB" id="2965at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9526937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="213" mass="22241" checksum="453F4126ACA07C22" modified="2023-09-13" version="1">MSGTIKGLIPSDVQFDGSSIRVAIVHARWNNKVTEALVVGAVAKLKARGVKESNIIIESVPGSYELPLACSKIIAGSHVPAASTVQDLLGGLNFGTPQGTPRSGTPAPTGGSVISAAMPNRPFDAVIAIGVLIKGETMHFEYISESVSHALMRIQLDTGVPVIFGVLTALTDDQALQRAGLTQGGHNHGEDWGLAAVEMASHLRRWGEGKFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNY1</accession>
    <name>A0A9P6JNY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNY1"/>
    <dbReference type="OrthoDB" id="3221235at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="13122" checksum="695F714A149FD4F0" modified="2023-09-13" version="1">MNILKSPFYSQLRTDLIPSDLDALLIRRFIREETTQIQREKLRAKEVYNNLVAKHLQYLELIDNHQKLVYPLRRGLPDDVLQEIFLHCLPRDGYVVLHLNKAPLLLANGCTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNZ2</accession>
    <name>A0A9P6JNZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_371857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNZ2"/>
    <dbReference type="OrthoDB" id="2793270at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="452" mass="50754" checksum="FFD4D2E13E8BD908" modified="2023-09-13" version="1">MASDLPQELYARIYALLHPRPDLLSCGLVCRAWFLCTRQSPLFRDVTINNLNADGFADLVMNPYSSFPFCIKQLTLNVDAIWFRRLLPFLQPLNATSLRLCNLQWTALEAHTQSKFIATFSKTIQRLVLGPRMTFESFVEATNVISQFSDIVSLAMEDVQWKTPQSPTPSKILQGESDRRAFSMYSLPTSCHSVSFMRCELGEIVQWLYAHTSFPDIHKLSIGNIKFRDIIHLRGLCCAAGPTIQEIALSFDVGEEGLGELDSSSILVYEGKVKKEIPGLNDIRHQAFRFGGIDCTIRSMCVMKQEGKNGLLLSLTTLYYDNFIYFTDRGRSCGPFFGVKSLAFLAARGADTLLQKITFVIMLQKVGDLDYHTIDWIGLDAILVYLAKAARQSSSFPSDGSLDNDKPVGGYPIRIIFELGGSADLEAMAALIQQKLPQCHQIKALIFREKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPB7</accession>
    <name>A0A9P6JPB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_854451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPB7"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040133501" description="RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="24029" checksum="A506D60746C30063" modified="2023-09-13" version="1">MITNVWNSAAIFFLALSSSLPLGVLSATRHDLQRRHHNTNYARHNETALVKRGGTNVKMSYYVPETGNEVACGGHYRNADAIVAISLASFDKAAHCGKAINIFYQGTTVAATIVDGCQICPPMGLDLAQDFYAAHYDVGPGMIFASWEFAGAAPAPSPSPTPTPSPSPSPKPSSISSSASASLTSSVAPSSASASATSSGQPTSTQAYSGLNMLDQVFVQMGGVATAAQNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPD5</accession>
    <name>A0A9P6JPD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proteasome complex subunit Rpn13 ubiquitin receptor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_855996</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPD5"/>
    <dbReference type="OrthoDB" id="340431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13314">
        <property type="entry name" value="PH_Rpn13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.70:FF:000001">
        <property type="entry name" value="Proteasomal ubiquitin receptor ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.70">
        <property type="entry name" value="Proteasomal ubiquitin receptor Rpn13/ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044867">
        <property type="entry name" value="DEUBAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006773">
        <property type="entry name" value="Rpn13/ADRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044868">
        <property type="entry name" value="Rpn13/ADRM1_Pru"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038633">
        <property type="entry name" value="Rpn13/ADRM1_Pru_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032368">
        <property type="entry name" value="RPN13_DEUBAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038108">
        <property type="entry name" value="RPN13_DEUBAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225">
        <property type="entry name" value="ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12225:SF0">
        <property type="entry name" value="PROTEASOMAL UBIQUITIN RECEPTOR ADRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04683">
        <property type="entry name" value="Rpn13_ADRM1_Pru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16550">
        <property type="entry name" value="RPN13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51916">
        <property type="entry name" value="DEUBAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51917">
        <property type="entry name" value="PRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pru" evidence="8">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DEUBAD" evidence="7">
        <location>
            <begin position="179"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="293" mass="31516" checksum="3BE6E15DE12C548B" modified="2023-09-13" version="1">MSLVGAQILLAFKAGRAFRREGSNTVIPNPTKGAIYLTNGADDLLHFIWRNRDTGELEEDLILFQFDASFVKVSQSGSGRVYVLKFASSNQRHFFWMQDASSTRDTEFVENLNGLLQDPDFHCHWSTLSSTGGAGPSSRAGASSSTAAGPASTSGFQATPQQLATLQQILMSGGRGAVAQAQAPDLSLTDILTPGNLLPLFTQHPELVPSLFPHLPPDLPVPPSADALQRIIHSPQFRSAVSNFDQALRTGMLGGLVRTLGLPEEAGTGIGPFLRAIQEQADREQDNNTMDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPF3</accession>
    <name>A0A9P6JPF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_727835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPF3"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="5">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="9836" checksum="DCBC3DE6E3E60639" modified="2023-09-13" version="1" fragment="single">TITDHPVVIFSKSWCPYCKAAKALFSTEFPDVKPEILELDLRDDGAEIQDYLLKKTNQRTVPSVFVNKEHIGGNDATQAAFKAGKLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPM5</accession>
    <name>A0A9P6JPM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_894919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPM5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="191" mass="21771" checksum="F835E58E47B6ED2C" modified="2023-09-13" version="1">MPTSLPNLQRLYFDAPVDISGYLWENLIVPERCIPAIKLTLDSESPTSLVVVELVDRFAGLITRHLNFSNTRFTFLKLEIRNSSFSFQGSPAFPGQIVTRSWWNSGPYFLHLRNSSLLQDLLIRVPNLQFSATSTITHLNLRLSTNFNREEGVMTRTINIMANLHSVTHLRTTEREIEFLAGHGLSLFPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPW6</accession>
    <name>A0A9P6JPW6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Urease accessory protein UreF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_855175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPW6"/>
    <dbReference type="OrthoDB" id="2550922at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="entry name" value="Urease accessory protein UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25693" checksum="EA8D7CEF64D34948" modified="2023-09-13" version="1">MVFLNPPHHTTALAFVSDAHAVVAQLDSDERVGETMKYLIELDDLYQSMTLNHVARRASTGQGVALLTLYSKGLSAPPSVTGWSTPSAEKERTERLSTLIDAFKLKIRLEATRGHLPVCWGILTAALGLSIERSQYLHLFLHARSLLSAAVRLNDIGPYASQQILLHVARPLVDAEVERCKSLRTGLVLKNEYNPMVDVTFDEEAMGPVSTWPLGEILASRHDLQHSRIFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ04</accession>
    <name>A0A9P6JQ04_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_357502</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10 11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10 11">Cytoplasmic vesicle</location>
            <location evidence="10 11">COPI-coated vesicle membrane</location>
            <topology evidence="10 11">Peripheral membrane protein</topology>
            <orientation evidence="10 11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10 11">Golgi apparatus membrane</location>
            <topology evidence="10 11">Peripheral membrane protein</topology>
            <orientation evidence="10 11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ04"/>
    <dbReference type="OrthoDB" id="10266042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051645">
        <property type="term" value="P:Golgi localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000003">
        <property type="entry name" value="Coatomer subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="13">
        <location>
            <begin position="291"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="158"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="537" mass="58165" checksum="AC40D42E17FB8047" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ46</accession>
    <name>A0A9P6JQ46_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_894510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ46"/>
    <dbReference type="OrthoDB" id="2898618at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF8">
        <property type="entry name" value="7ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="29497" checksum="97DD0F4B0F065A10" modified="2023-09-13" version="1">MSNDLRLSSLFAVDGKVVLVTGGGSGIGKMIATGFAQNGAKVYIAARKENQLREAVADINKVATGPKADYIVGNVASKAGCNALIAEFRNREDRLHVLVNNSGITWGAPYDNFPEDKGWDNVFAVNVKSIFYMTAGLTDLLKKDSTNLDPGRVINISSTASVDPASEGPLSADGSGTWSYQPSKAAVNHLTSSLAMKLGPSHITVNAIMPGLFPSKMTAYGIKSAGEDAFNSGQPTGRFGHPSDAAGLALFLSSPASAHITGTHILLDGGARFAHGVYAATKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ90</accession>
    <name>A0A9P6JQ90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Lysozyme</fullName>
            <ecNumber evidence="11">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_854485</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="11"/>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ90"/>
    <dbReference type="OrthoDB" id="6590422at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031640">
        <property type="term" value="P:killing of cells of another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06412">
        <property type="entry name" value="GH25_CH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000060">
        <property type="entry name" value="Lysozyme M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008270">
        <property type="entry name" value="Glyco_hydro_25_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018077">
        <property type="entry name" value="Glyco_hydro_fam25_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34135">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34135:SF2">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00641">
        <property type="entry name" value="Glyco_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00953">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="6" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040391880" description="Lysozyme" evidence="12">
        <location>
            <begin position="18"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9528365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="238" mass="25279" checksum="82F30363652F4D22" modified="2023-09-13" version="1">MKWLSILSLLSVAIVTATPIESEGAALVRRADPTGIDVSSYQPNVNWASVKASGVSFAYIKATEGTGYQNPSFSSQYTGATNAGLIRGSYHFARPDVSSGATQANYFIAHGGGWSADGITLPGALDIEYNPYGATCYGLSAASMVSWIHDFANTYHSSTGRYPVIYTTTDWWTTCTGNNSGFGSTSPLWIARYASTVGTLPAGWSYETFWQYADSGANPGDQDYFNGDAAGLKKIATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQX4</accession>
    <name>A0A9P6JQX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_725663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQX4"/>
    <dbReference type="OrthoDB" id="3023006at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="49616" checksum="DC1524963316A2E9" modified="2023-09-13" version="1" fragment="single">SSPISNLPPELLSLIIVFARSSKRVPHRIPYEVSTSHVSRLWREITMGMPFLWTKIDMFSTHSKSWVSAYIERSGQLPLDFNIDIYRSEKLYRRGGQSKQQAWPLISDVVQVLHRVRSMNILCYRQNTAVMLQNFFTDRPTPLLESFKIQHGTSFSAINASMGLKAFVFNQATPCLTTFVTDTPNILPRSDKLRSLETLYWHGLDPKLAINANNFQHTLSSVTSLVHLSLQGTVAFGFWPTGMPAGPQFTLPNLKALRCLDGGGTAIRTLLAISAPKLESIWLECSFDNFPAHFFGAPQMNVLGHPKFPALKFLTLHFEAFPFSEQFAKVFPTVSHVHYFHVNLRQSDKLAQAMKVLWTSVNTLVFSRFRERDAEKLTTALSQIILTRALGVNPMQAILLDEDHLRFIRKCHTNSARDVQLLAKVLSRDNYAEPWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRM5</accession>
    <name>A0A9P6JRM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_811601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRM5"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040443071" evidence="5">
        <location>
            <begin position="19"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="6">
        <location>
            <begin position="87"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="30333" checksum="6B60BD1CBA608410" modified="2023-09-13" version="1">MFYPLVFAAAASILSVYASPTSLEKRSGAVATNVYNDLVFYFKYASSAYGTVGCTRPNGNTLVSQISGLATDTQGFIARDDTRKEIVVALRGSSSITDFITDATIALTSYSSPGASAPAGTLVHTGFQTAWNSVASSVISSIKSQLAAHPDYSIVTSGHSLGGALSSLAAASLKANFPNNAVRMYTYGQPRTGNPTYAKWINSQFGENAFRGVHTTDGVPTIIPTYYGYQHHGVEYWDVIDPSNALTTRKCSASGEDLTCSASIISSGINAAHLTYYNVLASTTFCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS14</accession>
    <name>A0A9P6JS14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_891818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS14"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="30132" checksum="B0DE2AF70F720055" modified="2023-09-13" version="1">MSCFELGSIPLYGAEHKEIKIEEMEVEDMLCDVADEGNKESQLDVDEGVPVFEFKVYDKAKTTMQRRYPRGLPRESTLWGDDVGATENPLAVLLPEDLLNELHDYLPVCCVCEKPIVPSDEEFGNMLFKLSHCGHKLHMGCNFHLAEPFNTQACFAPKVKSKITPRPHPFLVIWQGDKEIKLYNAAVPNLEDADYVQPWVCPEEGCDIVYYSYLKDGVWNNWALQNSNGNVVTYKGKEIGGIRTSYIVKPAVYRFEAPSFQGTTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS94</accession>
    <name>A0A9P6JS94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_83210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS94"/>
    <dbReference type="OrthoDB" id="2978551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="300" mass="33404" checksum="68704CF98D738F42" modified="2023-09-13" version="1">MNLATLSNHNRINEILDPVRTTFNNYELLVQRDTALFKVYHGLMIGAVYCSDDSNVTVALSVDVVERLRTLSQVHPKIVGPRLLGSLWYHGRLLASFDRLKEAANWLESHGNKYSELVTADVEIGQWYIHLLLNLAEVLKDQGDLDRAKAILRRAAETGRSFSGAVNYNTAFLMCVAVSHEAGIENCLGDNTSALKLCKQSLSSARSNLRNTSIALFQLQHSKLLTADEEHGEALLEARESGNIITNASTTSCSRSINISPFGHPSFYEPGHHVLQMKRTLLKHLKLQNKVRKKPSESKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSF6</accession>
    <name>A0A9P6JSF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSF6"/>
    <dbReference type="OrthoDB" id="3360976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="11"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="157" mass="17352" checksum="DFD3C26D9989D20A" modified="2023-09-13" version="1">MILYLSTTTPWRSDYCTEDGRIVYKVNSPRNTWGGAKDIRITTLGSSATYSTLAQIDYYGESFFGEQSTITVGGTTLPAKAVLRKDGWAIFGYGDRLFQGPDGQIYRWTMDSTKCRLFKKDNDGTLVATYHHESLGILSAARPASLEISASGEQIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSL1</accession>
    <name>A0A9P6JSL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSL1"/>
    <dbReference type="OrthoDB" id="2688840at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="41784" checksum="8822D475C93A05F7" modified="2023-09-13" version="1">MSAFRPRSHSSDSPVKSPHSLDISRKTCSKRGHSHTPSPTAADVGLRKRRRRDHSLSMSESPFTSRKSLFTSNNEHPGSKPVFATTSTQFNIFPKQSHRSSSPCQSSFSNDPPPQSRSPGLLDDLASLRSAAFWELRQSVAESGEGLVQRMREYERSRSRHQAHQRTRVLERSGRKRSAWRMRNQASLPIHPPSEASDDEIPTRHSTSFEHSLVSEGQGLVRPVEPMDVDVGDASYGEQQYKDFLSVTHKPASATSNSTTDEDEDEDAIFIGTLNSSANFQNEPRLDVPDIDSSASSSQSITGSPCSSVISLLLPKADPLEEDPFSAQYPSTTSEKALAALSIAFANGAGSISDYSPVWEYQRRFNTEEYDHGDLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTK7</accession>
    <name>A0A9P6JTK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NudC domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_806226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTK7"/>
    <dbReference type="OrthoDB" id="428655at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037895">
        <property type="entry name" value="NUDCD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664">
        <property type="entry name" value="CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664:SF1">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="6">
        <location>
            <begin position="307"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="676" mass="74786" checksum="25029BD42650368E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTK9</accession>
    <name>A0A9P6JTK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">allantoinase</fullName>
            <ecNumber evidence="6">3.5.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_848537</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-allantoin + H2O = allantoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17029"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
            <dbReference type="EC" id="3.5.2.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.5" evidence="6"/>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTK9"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000032">
        <property type="entry name" value="Allantoinase Dal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017593">
        <property type="entry name" value="Allantoinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03178">
        <property type="entry name" value="allantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF2">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="10">
        <location>
            <begin position="63"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9531665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="456" mass="50288" checksum="5155A10BDA221C06" modified="2023-09-13" version="1">MSKLLVCTGSKVLLPDTLTPVPATIVIDQNTGKIIEIRKTHLNRDQYSNESASIKWIEAGNYVVLPGLVDAHVHLNEPGRTDWEGFWTGTRAAASGGITALVDMPLNSLPPTTTVPNLQEKRDAARGQCHTDVAFWGGVIPGNQEHLKPLIQAGVRGFKCFLIESGVDEFPFVTEAELENAMKELDEISGVLLFHAELDDDFDRLDKPDPTEYATFLASRPQQLETKAISLVIKLQKRFPNVRCHIVHLSAASALPSIKEAQAAGLPLTVETCFHYLTLAAEEIPDGHPEFKCCPPVRETSNRDKLWEALREGVINCVVSDHSPCIAKLKHLDDGDIMKAWGGISTLGFGLSLLWTEGKKRGFSIGEVVDLTSKNAAEHAGLSTQKGQLKIGFDGDFVLWDEEAVYEITKDVLQYKNKISPYEGKRLSGRVEETYLRGNRIYSRSAGFESPMGKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUW9</accession>
    <name>A0A9P6JUW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_846131</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUW9"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF79">
        <property type="entry name" value="LACTOSE PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="87"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9533254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="562" mass="61883" checksum="ED74A613FC048F5D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV18</accession>
    <name>A0A9P6JV18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_879926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV18"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="234" mass="26180" checksum="EE94165D42138A75" modified="2023-09-13" version="1">MSYNSSIALLNQAQVAFHAGDTRGALEWYYKGIKKILNDENVTALAPTVITLDNYPHELLGLAWSGFLGCFKDSSLGLNENTVPEAYKLLKTFRPESNSAQFLKWSARFQNSERGRILLKGLQISVGFTLGLMAWNNKDRATAARRYQEALDLAQTHAPFMSFPNTPVGLERCVSRDVKDMQDNLEVLEHNDTIHASLGASLGQSTNRRDVVEMPDTVRMKRTEGNGKNFLLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW14</accession>
    <name>A0A9P6JW14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_889442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW14"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="51" mass="5819" checksum="F037DF2E5AC01049" modified="2023-09-13" version="1">MATHPLLAVQLQGNMAGHKVFKRVYIRILDVKLRLENIGDMWPEEGTNANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWJ0</accession>
    <name>A0A9P6JWJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter NIPA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_803611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWJ0"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="542"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="625" mass="69185" checksum="77896E1F271617A9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBJ1</accession>
    <name>A0A9P6BBJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158227">
        <property type="protein sequence ID" value="KAF9521238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBJ1"/>
    <dbReference type="OrthoDB" id="3259181at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="88" mass="10136" checksum="4B9C479CEFD9C7F6" modified="2023-09-13" version="1">MLSSRCSKILQTYDQPSRRRGHWSYITPRRWRQYFLAPSRPIFTVFLLGLLARSLVLTVTPTTHFRMNEMLKTHSNPGTGACASTQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BCC1</accession>
    <name>A0A9P6BCC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_926533</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158043">
        <property type="protein sequence ID" value="KAF9521495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BCC1"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019783">
        <property type="term" value="F:ubiquitin-like protein peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="25"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9521495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="16268" checksum="39BB3DFADE6732D0" modified="2023-09-13" version="1" fragment="single">LSASEDEEVTKILNQSGQVAIVGRYSLTDKDMERLKPFGWLNDEILNCYCEMIRGRARHSKLDWQLLTHPSRVTVTNRNVLVFDSFFFSKLSKGYFECNINRWTKNENIFAKDLILIPVNHSNNHWTAACINFLEKRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3U1</accession>
    <name>A0A9P6E3U1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157970">
        <property type="protein sequence ID" value="KAF9521953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3U1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6873" checksum="5E8DF8422B31277E" modified="2023-09-13" version="1">MGGLSTITALRHLSHYLPIKSFYKRLHPSIRGLNDFFSRELRLPLYPLCFNSTSTTPYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3U9</accession>
    <name>A0A9P6E3U9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_734389</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157967">
        <property type="protein sequence ID" value="KAF9522000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3U9"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="8">
        <location>
            <begin position="116"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="24590" checksum="88A31C7E1639DD2D" modified="2023-09-13" version="1" fragment="single">NPTLKATQLCPFCDNRLPDSPSARLLAALKVLKAKTWLDPLPENPFHRSATSFRVYVDFCTQHRHEKSEIPQAAAAGWLLDVDFGGIFDRVSRNVVCLAAVKDDKENVFFKQALNVYKGDSLRMQGVSAQYSHFDRIGAGYYGGPGNHIILTTLRHLFPKSSIPANDIHPLSYSIYLEEVLALEAAVLLIQDDLKLSYSDAVSVLRESRQFGYNRYDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4B3</accession>
    <name>A0A9P6E4B3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-glucuronidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_911422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157951">
        <property type="protein sequence ID" value="KAF9522314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4B3"/>
    <dbReference type="OrthoDB" id="2796951at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040381455" description="Beta-glucuronidase C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="2">
        <location>
            <begin position="418"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="56215" checksum="4AF96684756141FF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5C2</accession>
    <name>A0A9P6E5C2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5C2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="14441" checksum="50CE6036BC287551" modified="2023-09-13" version="1">MDEQIELLIRVLFTQSAIGVETFMWIFGLCVLLETPRERRKRRAIYLAVSFVILVLDCFFKFPMANFSFELLYRPNRAKEVDDLREELFETWYVKRSDWASAMIMWIGSGLLVGSLYLISKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5U7</accession>
    <name>A0A9P6E5U7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_863418</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5U7"/>
    <dbReference type="OrthoDB" id="2117453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="11"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="18574" checksum="AA41535C12E4AE00" modified="2023-09-13" version="1">MAMDAIVRRGHPVVFGLLVLFAIIELCITAFVTAKYNSHHNYPNRSTRDRVRYLLFLSVWTTVFGAAFLGMFLVFMDNILVSVASHFVFLIITWILWLAAAAAFTSSIGGALNCHTQSFFVYCGQLNAIEGFAWLIWVVITLLLVFVLIRGIISQKRGDGVRGGLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5W7</accession>
    <name>A0A9P6E5W7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GTP-binding protein RHO3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_799863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5W7"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017157">
        <property type="term" value="P:regulation of exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000780">
        <property type="entry name" value="Rho GTPase Rho3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="207" mass="23284" checksum="B52CC5917C04B5DB" modified="2023-09-13" version="1">MALCGTSKGNSFGRGRPIQRKVVVCGDGACGKTSLLNVFTRGFFTQVYEPTVFENYVHDIFVDEQLVELSLWDTAGQEEFDRLRSLSYAETHVVMVCFSVDNPVSLENIESKWLDEILEYCPGVKLVLVALKCDLRDDPAVKERLKRYGTSTVQYEEGLAVARRIRASRYLECSSKHNRGVTEVFYEAARVSMGTRPKGSGDSCRIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6B8</accession>
    <name>A0A9P6E6B8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thymidylate synthase</fullName>
            <ecNumber evidence="2">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_799646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6B8"/>
    <dbReference type="OrthoDB" id="766at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.572.10:FF:000013">
        <property type="entry name" value="Thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate synthase/dCMP hydroxymethylase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="35341" checksum="6B126DD6E6703C52" modified="2023-09-13" version="1">MTPTFSSLSLETKEHDEVQYLKLIRRVIDAGEIRADRTGTGTLAIFAPPSLRFSLADNTLPLLTTKRTFLRGIIEELLWFVHGCTDSTLLNKKGVKIWDGNGSKAFLESRGLAHRREGDLGPVYGFQWRHFGAEYADCETDYTGKGVDQLRECITKIRENPTDRRIILSAWNPKDIPQMALPPCHMLCQFYVSLPPPAAPSSQKPKLSCLMFQRSADLGLGIPFNIASYALLTHMMARVTGTEAHELIIQLGDAHVYRDHVEALEEQLKREPKSFPKLSWARDDITDIEDFVYTDFTVDGYQSHPPIAMKMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6N0</accession>
    <name>A0A9P6E6N0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6N0"/>
    <dbReference type="OrthoDB" id="4791458at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.20">
        <property type="entry name" value="Cytolysin/lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015926">
        <property type="entry name" value="Cytolysin/lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009960">
        <property type="entry name" value="Fruit_body_lectin_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07367">
        <property type="entry name" value="FB_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63724">
        <property type="entry name" value="Cytolysin/lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="15924" checksum="F3495A35B0D4EDEF" modified="2023-09-13" version="1">MSYTIETHVHKNSANKVFDCVEQCVWYYANGGTWATTSDGFKLTMGGSGTAGLLRFMSQDGQEAFFVAMGVHNYKPWVDIITGLGNDVTGVKALPEYYNDTNPPRVASRESQRTSQSINSITNRVISVNYTVAEGNNLKLDITIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E889</accession>
    <name>A0A9P6E889_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_839097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E889"/>
    <dbReference type="OrthoDB" id="2111841at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="39084" checksum="B5C2E75FBB98DABD" modified="2023-09-13" version="1">MAKTLGSPENLQVVAMLKKANTNSDFNYHLLEMQAFSQSLDSASIAAELAKTHDISVPSAHVNRNSPTAAYHIASTEKARILYKVYQSATTSAEKVSTSSLKKEASASFAVSSKIAQTSIASRLVKKEEDVDDNTTLLNSMKKEETESVTDLPEEYAINTAKWNMLSWTGRVDALLSVTVKVRNKERVESTCFVRHSDSRLMMLAGLFQFNPNDPIPLRFCTISTEKPVYTLREIESKKKEDAEPEGSPRKKTKGKGKKAAANMPPGYLSKKLKLPGCQDLARYFEPCFEYKHKQLLSPRIDQDAPLVWYEIESGKRSSHPTWIKPVYDPDQSVESESSDGDEEDSEDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8X2</accession>
    <name>A0A9P6E8X2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_820057</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8X2"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040537039" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="298" mass="32013" checksum="62DBE85BE505A377" modified="2023-09-13" version="1">MHIPVPVIHLFATVLISLPITLVTAASLKAVSHFGSNPTNIQMNIYVPDKLAANPPVILAMHPCGGNAQGYYGMTKLPSYANKYGFILIYPQTTHDFNCWDVATNASLTHGGNGDSAGLVSMVNYVIMTYKADPKRVFATGSSSGAMETNNLAGAYPDVFAGGASFSGFPYGCRRGASSSSPISDTGCPLGQVVKTQQGWMDELKKGFPGYTGSYPKMFIAHGTADNLVVFSCYTQQMMQWSAAHNITLSKEVTNAPSSGYTEQIYGDGTKLLGIVQQNGQHFTPYQEEMVLKFFGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9B9</accession>
    <name>A0A9P6E9B9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_897625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9B9"/>
    <dbReference type="OrthoDB" id="2739948at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="238"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="501" mass="56589" checksum="2A3042C6ED4E1923" modified="2023-09-13" version="1">MTETPQLPAPGVPPTTSGGTPVKKKQSSTSRHPYPIKTDAAEEGHHTVKHNMGLEIDGEVVGGMPFRAFFQEFLPCADEAQLAKFLADIPTDLFNKIPTTSRKGRSSTAKKRRRTDEEDSESEEDTEDEEEEDVEEDEEADEVSAKGSLPKVWEADMYPSLIKLLNEYRIQTREPGDDVGLYKDGEEPAKPNRPHFSRIAMPVEIKPAGSERPFHDAPPGLNQDARRLHQYLPNPDSKAFETLGQLASVMTEICSRQFRTHVFMVYPRDPDVCFIRADRSGVLVSTSINYRQQSKLLAEFFWRFGKATDAQRGLDKTVHSPTDDEIILAKTHLKSNSRLERPIFRIDVPDGEGFRSVLAREALCDPESLTDRGSRPIPVYDLKAKAVRFLKDSWRSEMLEKETAILAQLNEAKVFNVPKCVAGGDLYDQNRFPYHRTATQKYVNADWRSGPLLPLEARVHHRILEDLILNSINDCKNAREMMLSLQSRLGVPSPNKSSFQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9K5</accession>
    <name>A0A9P6E9K5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_576542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9K5"/>
    <dbReference type="OrthoDB" id="5307922at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF30">
        <property type="entry name" value="SERUM PARAOXONASE_ARYLESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="475" mass="51867" checksum="ACD5093B7827CA7F" modified="2023-09-13" version="1">MKVACVSLHPTSITMKSVQVSAFLILIVSITLYRRGSGINKFSNHGKFPHGYYSAGDYGEDCVTLRNQADAPDAERFQFCEDATLWDVKDSNGKNVDRPLIASCDSGRKQWNTVMGPLKDPEPHGTLWLYVPPSDAFLRSRRDSFSSIPDELRGKPHRITFINYPANHDFHPLGVAVWPSQGGNTSNLYVVNHARQKSVIEHFTLHPHNPTQATHVRTITSLLFVAPNALALTSPNSFFMTNDHLLTRRLPFIGNHLAGIETQYRLPLGHLLHVRLNAVNQGTIPTFTHPTIQHISNTHFSRLLIPFANGVALSPSGNELAVASSSTGKVFIFDRDPSTNALKQKDKLQMPFAPDNLHYEASSNPEKATLIIAGHPDVINLVKVAAGHPGASAKSWVIAAVPGGRTNTTAATDDIRKSDRWTSETLFQSAGVEDIGGFGASTTGLVDSDTGTLYVPGLYSKGGVMMCRPNLPPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9W0</accession>
    <name>A0A9P6E9W0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9W0"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="427" mass="47771" checksum="1CFF85C28971E2FA" modified="2023-09-13" version="1">MDSDCLLPVFPVEIFSNVIESLHNDHALDTLKSCSVVNGWFQTLCQPLLFSTVKIGEAHARSRGVQELGFYSKPIKAQQFADTLRRSPSIGVFVRSLKYTVTPADFGIPHLNEALKQLEKIESLSVGYSYRRDLGQWNPEDYERLSMDWQTCPLLPGFLHLFNKPTLVHFRFGDIIHNFPIEHLVHCSNLKALSLDVDMTSSQVQSTLFCDPIRLEELTCSTGGRGGALQVMRTCQSNGTSVFDLTNLKLLSTPLLRDQWFDDPFIIQYAFKHAKNLEHLQLSVTSMTSCENLYGDILTPKALQAVKVLDVLLLHATISVIDPYLGLCNELKKMSGKNNVHELKIGVTLQALSGAMESAFSDLEEVVSGTGWPCLKKVRLAIQIPQRGLAESEHKALLQTLRTTRFPRLASSQTIAFECVSHIGRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAB7</accession>
    <name>A0A9P6EAB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAB7"/>
    <dbReference type="OrthoDB" id="8963340at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="134" mass="15279" checksum="FB42F17306737273" modified="2023-09-13" version="1">MTNSLTMSFESTTTLPLASTNNSQILLDRNGASTPGLDQNPYTVLATAGARVYHTKLTAEESQWTYSRWKGTLSFCRDIDTPSTISKGVSETEKHWFRLADDETGRTVWMFKFPENFDYTIDRPFFQVFQGRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAJ5</accession>
    <name>A0A9P6EAJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAJ5"/>
    <dbReference type="OrthoDB" id="425354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="22088" checksum="9F7C9A2D7C08D495" modified="2023-09-13" version="1">MAVPTEMTSLNLSGVYALNRSLSDDNVMDEIMRLQGIGWLPRQASRTANITIMVRHFKDESNIEHFDIHQMVSGGLGLPSNVEKRELCWKEAELETPLFGSILTKARRAHVNELDETFLREGWTTDTLDHGVVEILGTSNTEKSGTTWTASQALGIGEIEGLRRYIRAVHFTGPEKEKFQTRVIFDYVGPLNENLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBB5</accession>
    <name>A0A9P6EBB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_511014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBB5"/>
    <dbReference type="OrthoDB" id="2367075at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="240" mass="26835" checksum="F3D30FF1261FE9FA" modified="2023-09-13" version="1">MNTSEESDPVIQSSEGASVMENDDIYYFDFVVFEVENTRFFEFQKLASCNIRAPTPSSYAECLGALDLATKWNMSGMRERAIISLNRMMKAQTETKSIVESILAAKKYRVDGWVSAGFIKLIGKLEVDMEDLELLGWETAARLLDARFRITRVQLLGEFEERPEETCEECSGDSSLGTKPICKWGCGERGCFRRCAGCAGGAPSKCVYKCGNWSRRDFLNSSAIQTQFVRILASESLAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC02</accession>
    <name>A0A9P6EC02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_940428</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC02"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="184"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="487" mass="52893" checksum="CAE24CF72CE4E147" modified="2023-09-13" version="1">MTHTTIVRNVSIARRAGAYVIGSGGRSPLSSGGLSPIPSALPSPNPSVEPKPTTHSPPSGGSSEEDGSGSSGSISIEHATPTTDTGISSPLFYYLDGTQTPSPNPDKMFDQSAQLASAGGPTPARPTIVINDTPLSASTAEPTGLGTGALTPLSPFQRYRGWLSDVVAPLEEFIDEQVDPREHYLDLNEIAEGESGSVFSATLSPANADRLRLSDAIKELDALELATEDVKMVAIKSIAIVPSGSPKLVDLQRELTMMKGLWHENVLGMDAVYVDLVEDSLWVRMELMERSLADIVGLVETGLMLQERMFARFTSDVLLALGYLHKHQIAHRDVRSDNLLLNKHGVLKLADFSNAVQLPTENSMREDVVGVAFWQAPEIRRGPYNALKVDVWSLGATVWEMAETQPPFADTKQLADRWPPVSQPELYKPAFHDFLRKCSEPSISRPSAEELLKSSFINNACGRPVIVQLLSQCMAIEKLLQEQDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC63</accession>
    <name>A0A9P6EC63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_885112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC63"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040489939" evidence="1">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="171" mass="18832" checksum="B194E930B7F6D449" modified="2023-09-13" version="1">MRFGTLIASSLLVCVTLVSAAPIPAIVDVEARQTTNGCTKYTCTREEMAKREIEARQATTDGCTKYTCTREVEAKREPEPVAAPEPIVEARQTTDGCTKYTCTREVEEKREPEPVPEPEPIVDARCTKYACTREAEPEAQPEPEAIPEPVAESIVETRQATTNGCTKYTCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECB3</accession>
    <name>A0A9P6ECB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_492937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECB3"/>
    <dbReference type="OrthoDB" id="2991366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="643" mass="71145" checksum="47689D8B60D7A329" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECZ9</accession>
    <name>A0A9P6ECZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_447069</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01377">
        <property type="entry name" value="MYSc_class_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.4820:FF:000002">
        <property type="entry name" value="Myosin heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000101">
        <property type="entry name" value="Slow myosin heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.360">
        <property type="entry name" value="Myosin S1 fragment, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.270.10">
        <property type="entry name" value="Myosin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008989">
        <property type="entry name" value="Myosin_S1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF857">
        <property type="entry name" value="MYOSIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02736">
        <property type="entry name" value="Myosin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="12">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="11">
        <location>
            <begin position="77"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="195"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="705"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1260"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="893"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1098"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1273"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="170"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1360" mass="155489" checksum="27B451787A45B431" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED45</accession>
    <name>A0A9P6ED45_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED45"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="197" mass="21692" checksum="BB788454BDA6CE65" modified="2023-09-13" version="1">MSFTMAHTILLPHPISKVFPALSESQHMERLQKLTPEAQTFTLLPFDHVQLPATGLASFSLPDHPKSAEGLPRPLTMEAIPANANVKNGHVVERVKFEFSGVATQLFGLVKSPISVSGAQIVDTRSRTVLYESVEGAGLKILKARTCEEVVMEDGKEGTKVKETVWGTCPVYLVWLVKMIAPGLHQKAMDSYHNLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDT7</accession>
    <name>A0A9P6EDT7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_856550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>melleolide F + FADH2 + chloride + O2 = 6'-chloromelleolide F + FAD + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67160"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:167712"/>
            <dbReference type="ChEBI" id="CHEBI:167713"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:67161"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin-dependent halogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDT7"/>
    <dbReference type="OrthoDB" id="3340390at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140907">
        <property type="term" value="F:flavin-dependent halogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050816">
        <property type="entry name" value="Flavin-dep_Halogenase_NPB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747">
        <property type="entry name" value="FAD-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="516" mass="56414" checksum="817997C43EF7A513" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEB8</accession>
    <name>A0A9P6EEB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_768681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEB8"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="98"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="42581" checksum="A6B660AF894C2D57" modified="2023-09-13" version="1">MNVKRVTLTSKKNWWLVEMNQEEETQASHTSTNSFSSTDTAVEGHSYDQYNHGVEESERAMDETDTPPPSPIYKPPHHPTSIFSFPTPTAYAAPPNPTDSLTPFAHGSASELFKCVVKKPDVVQLEINGEMQSNASDVTVQFLAELRVYTTVARHRNICAFLGSLENVGMVLAFIDGRTLYDVISERPPLTNVQKIDYHNQLLDGLSHMHSYRLSHGDLSLLNIQVTSRTNTIKLLDFGRSVSADSVFKSPDDEPVDPFPYLARNRTSLPPLKLPTVKVEQIHPGTRPFSAPEILRGECTDPLLADAYSFGMVIVCIDRCESVDVKPWDQRKDKLPANLFEGCDLFQARAREYLKRWDQGRRRLDREDMIVDIDMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EER0</accession>
    <name>A0A9P6EER0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_869903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EER0"/>
    <dbReference type="OrthoDB" id="2153847at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040258691" evidence="2">
        <location>
            <begin position="21"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="24092" checksum="76C6359995F7918F" modified="2023-09-13" version="1">MFSASVMFFTMACLVASSLGSPYQRREVPQEHAHQKFLTNVTALLQSGNAAENNPLGILDAVFGLLGNAAGAQGAGKVTDVTCLQQATADQAFTNAKKTGDVVGMTAALAYRTLERNTGKVGLKSDLCTSIKAVNPEIAVLTQHQDPASGGAKEGNKAIVLELARQIASVNGDPLVALQTGTFAPGDPNDPTGKGNSCDDQPDPIGCIETKNLLVPDATEAEILAAVAGNGGAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFL8</accession>
    <name>A0A9P6EFL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_854925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFL8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="51" mass="5716" checksum="EB500DB180BBA471" modified="2023-09-13" version="1">MLTNVEGCTLNGPHSPTVNYHISSKILSHFPAIVELFGRVQRWDFSTPMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFZ4</accession>
    <name>A0A9P6EFZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_854806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFZ4"/>
    <dbReference type="OrthoDB" id="3184970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32314" checksum="D51FE0D76094530F" modified="2023-09-13" version="1">MGSAVIHEEFNSANADITIQSCDNVRFCLHRKNLEVTTGGLPGKTSDMIDGVLYLPEPAKVLELLFLFTYPQRSPTHLHDLDCDSLLDISEAAEKYKVFFAISVSVSGLRSFTSTEPLKTLRHALKYDHLDLADEAAPNALFCNPTLVVTGLSDTYIVPWLLYQSLAYKKIFEKAESTLKAFQNTFTYCKVEQRGICVTCRTVIAAWIWQLKQLSTTEALLFELEKFEQYPNSNLELARDFCEGSCNTHRRCIYAAEISEHCKVGLQKSQKFSEYLLDHRVEDGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG19</accession>
    <name>A0A9P6EG19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG19"/>
    <dbReference type="OrthoDB" id="3233595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="17"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="356" mass="37819" checksum="756A567CD09B2B6D" modified="2023-09-13" version="1">MQAELKQIALTIREKFGPFVLSEAPIYKPGPGEVLIKLCASALNPADWLIQKSGRAVEKYPAILGFELAGEIVDVGPHVENLKRGDRVLTISRFIQNEFMCFQQYALGAAATIARIPDNITYEQAATLPLGLSTALTGLFSEFPHGAGLVPPFTPTTEGKYHGTPIVIIAGSSSVGQSTIQLAKLAGFSPIIVTASRRNTDFLMSLGANYVLDRGLEVTAFSEAVGVITAGKPVEIVFAALTNPETEKLAVSVLDKGGILISSNPDVSEIATKAEVKIAKVLASPSVPWNARLFTDFFTGKLTGWLERGDIKPNRVEIVEGGLAGVVGALKKLEENAVSGTKLVARPPETPALSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG71</accession>
    <name>A0A9P6EG71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Yellow laccase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_853534</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG71"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000045">
        <property type="entry name" value="Laccase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="44"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="156"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="359"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="509" mass="54579" checksum="0267D22EBB48907A" modified="2023-09-13" version="1">MYKIRGSLAAIGPTADVHIGNANISPDGFSRSGVLAGSSSGSLSFPGPLIRGFNGDTFKLNVIDGLTDTTMLTSTSIHWHGFFQSGSSWADGPVGVNQCPIAAGNSFLYQFSTASQAGTFWYHSHHSTQYCDGLRGAMVVYDRHDPHRLLYDFDDESTVITLADWYHTPAPSAGLVPTADSTLINGRGRYVGGPTVPLTVIRVLPLVRYRFRLVSISCDPNFVFSIDRHSLKIIEVDGINVQPYTVDSIQIFAGQRYSFVLQTGLAIGNYWIRAQPNVGTQGFAGGVNSAILRYWGAPNSDPTTTSTVSAPMVEGNLHPLTNPGAPGTATPGAADVTLNMDIQFDFPTLKFKVNQATFAPPTVPVLLQIMSGAMTASTLLPSGSVYVLPPNKVIEISIPGGSVGSPHPIHLHGHAFDVIRTSGSSSYNFANPVRRDVVSAGLAGDNVTFRFKTDNPGPWIMHCHIDWHFDIGLAVVFAEDAATVSTSNPPTAWDQLCPTYDALPPQTFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGD8</accession>
    <name>A0A9P6EGD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoporin Nup186/Nup192/Nup205</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_853182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2019644at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2105" mass="233109" checksum="E484E2DCD55A9BF7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGH9</accession>
    <name>A0A9P6EGH9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGH9"/>
    <dbReference type="OrthoDB" id="3262423at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="88"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="508" mass="55947" checksum="C2EB3B79F9137F00" modified="2023-09-13" version="1">MSVIIPLSSPPSYTPVEAISDDPPSLDDQQEANLGSQLPTYANTVHRGGVSPATSSTPSSVKEFTFSIKNRGKSLAVLTVIANRNVSNTMPTFIEGQPIKGSVRLNLGKAEAFQSVTIRVRGNLFSRSGHQTTFLDTSHIIWSQSMGDPRHTASKFTLKSPNRPESNTSIAATTPFTGKIVEGEYFWEFSIELPKEVPVPVGKDRNPKIFLLAQTFAERHIHASVAYEMVMKVTTTNFLRMNHRTLVQLGFIPVTRPPPFPPLRTLAYQEGSPLLPPSVDPDGWQALEPVKFRGLLFKSITVELECTLYLAKPLVYTRSTCIPLYLEFSGENAQALSLLSAPKAVACYLRRYVKFDDDAMVIKEPISTLSLEGTPDKLMVQDSVMNSQLAVWWKPDTKIAETNYLTHCTCLLGELHLGSNLKPTTALGWFEIKYSVVLLPFEVAGFDPETSIPLIKKPVEIVTAFAPGPRPRMSAPPGYKIETTMHLEAPNIGGTAAMMGMSDMNFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGY8</accession>
    <name>A0A9P6EGY8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T-complex protein 1 subunit zeta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">CCT-zeta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_852633</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGY8"/>
    <dbReference type="OrthoDB" id="10052040at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000038">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="59933" checksum="55620FE02A10F7EF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGZ3</accession>
    <name>A0A9P6EGZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">614/534 cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_790010</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGZ3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9529433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="517" mass="58697" checksum="8B6032B281A0188B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH10</accession>
    <name>A0A9P6EH10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_854373</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH10"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="213" mass="22686" checksum="9F5979B00CA721D9" modified="2023-09-13" version="1">MILTSTARSLITAPGLGRRAASGIAAKYSQALFGAALAKSPQTLTKVHSELVNVSTAIKKDPEVATFVKNPTLSLQERNKGLQGIYAKVESVGPKKEPLSDITKNLFTVLSENGRLYETEGVIEGFNELVAKHKGEVTVTVTSATALPKDILNRLETTLKQSETGKAAKVLTITNKVNPSVLGGLIVDFGDKTVDLSVQSRVTKLNNVLTQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI66</accession>
    <name>A0A9P6EI66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_262491</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI66"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17998">
        <property type="entry name" value="DEXHc_SMARCAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000014">
        <property type="entry name" value="SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="563"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="942"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="135"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="207"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="287"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="345"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1114"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1114"/>
            <end position="1126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9529360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1146" mass="127522" checksum="8F591C8439DBC630" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EID1</accession>
    <name>A0A9P6EID1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_835043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EID1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="29470" checksum="5CF2FA8458E6AE5E" modified="2023-09-13" version="1">MCIPKLWPSRSRGQSVSPAPSQVPVHENDVGDVEINRISSIIECISHLVLNIPVYKQVLTEREIWTQTQKTLSVDVAFLLCLNNTIGEVTRTSEQYQETLCLIATSLQLISETSMELQSKQLSTTEATADIESIKRHLEMTRNNVKALALNEASKGNTNLWDTYQQYQLSHGQFQGLTNSNIQTSPGPSRQPSASPSGPPQQSDNEAQHRATPAPVSGSSALFAGSTNPGVTNSVLCTSASSITVDASNSTNHFHLHSACDGTACPSKPLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIM8</accession>
    <name>A0A9P6EIM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA (cytosine(38)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.204</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA (cytosine-5)-methyltransferase-like protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_892666</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.204" evidence="4"/>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIM8"/>
    <dbReference type="OrthoDB" id="414133at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="369" mass="41306" checksum="498D666F6332CC8B" modified="2023-09-13" version="1">MPIRALEFYSGIGGLHLALSRTELDAQVIQAFDWDQTACQVYSANHGGIVNKVDISTLTATQLAGYKADLWLLSPACQPYTVLNPNAKGAMDPRAQSFLHLIQNVLPELALSDDHPQRLLVENVAGFEACIAFSSTRQILVSALQSTGYETLELLLTPLQFSIPNSRLRYYMLAKRKPLSFHAVQGDSSRLWRQIPGVGIPWTDPRLDEESYSTHSTLAIKEFLDTSEHTGGCFIPEKVLLKWGRLFDIVKPTSRRTCCFTRGYTQLVERSGSILQKAEILDTTKIFDDFLAAQARADEDPVKILRPLGLRYFSPEELLRLFSFDSLSPSSGPSFTWPPNISTKSKYKLIGNSVNVKVVESLIRYLFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJN1</accession>
    <name>A0A9P6EJN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJN1"/>
    <dbReference type="OrthoDB" id="3145912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="397" mass="45809" checksum="17736698377088AA" modified="2023-09-13" version="1">MNQRPTLETMSSRLWTRLPLELMREILVILAMTSEREARQLRLVSSDINVLVLPLIYQHIIITKLEDIIRLTTTLLPKRKHYIPALKSRLHIIPRSLSTYQVESCSLVLNDRGPFIETALASIAPVFSGVSKLAITARNLQAHGYWLREHPIRPNTVMLLHYGSPALVNFYDPIFQNVTHLYTSITTGHRYSSVSDLPLLTHLAVSTRPYLPEQTAKNIAASLRLILNQCKRLRMLVLVMDFGNISDADWLHPLWQSWLEQCDTDNRFVLLPDYRPPRIEWDDMVNEDSSSSFVSMTPSSSQTELDTHRKFETLWGRALSWKNRSKNSMITWFADLEEREAWRAATKLKFEELEAAGFFTNYCGPEWEIDLVQRDNYQHPPASDPDLKLDGFQSAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK19</accession>
    <name>A0A9P6EK19_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_849529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6288785at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48209">
        <property type="entry name" value="AGL056WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48209:SF2">
        <property type="entry name" value="FI24008P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="45"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="909"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="749"/>
        </location>
    </feature>
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        <location>
            <begin position="836"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="860"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="926"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1165"/>
        </location>
    </feature>
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        <location>
            <begin position="1171"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1207"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1310"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1359" mass="146066" checksum="36AFE9D98EFA80C0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK28</accession>
    <name>A0A9P6EK28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_905628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="3349377at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="170"/>
        </location>
    </feature>
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            <end position="218"/>
        </location>
    </feature>
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    </feature>
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        <location>
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            <end position="304"/>
        </location>
    </feature>
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        <location>
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            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="579" mass="65858" checksum="26B15E683D1586B7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK94</accession>
    <name>A0A9P6EK94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_179959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK94"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="11792" checksum="6203ABAB6F141A1F" modified="2023-09-13" version="1">MLHFMRSLGSFISSLQLSSTDGNHRVLRLSMNERPSGLRLTLRWKIGFGNKPECVVYLLRSSLRFRNAIFYNIAANLPLASLQLLCVFVHVDAQVLAQAFGKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELT9</accession>
    <name>A0A9P6ELT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_106535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELT9"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="43"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="2">
        <location>
            <begin position="128"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="30655" checksum="08F001D3D5356BBF" modified="2023-09-13" version="1">MNRDNFPHFALATNMSARNHAPTTLILYDVRGQCDQSWLPSIWRIRLILNYKRIPYKTEWISFQDVENTLRELHVPPTSQRSDGRDVYTLPVLWDQGRRKFVSDTNRIAEYLEGISPARPVFPEGSKALQSLFVYFVQEVFSKPLLPIMVPLSHQQLPDPAQNYFRPGQPPANMLTGHQREQQWRAVQAQFDFLDGIISKNDNDGDGVVVMGRDLSYADFAVCAVLLWIKRMAGNDGWARVRTWNNGRWERLLDRCREFMDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM44</accession>
    <name>A0A9P6EM44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM44"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="206" mass="23069" checksum="F47C179418808FB7" modified="2023-09-13" version="1">MVSKVELPDNDSSTFARPQDLVATARLYGAIEATIEDLVRVLETTAVEGHPGLIVTLEQTSDWIWREVQGVPVQFLPTLKACMRHYERTLVDLRYCILEAKPRSMEATQSLICRLEESIQALDAALQDFTLSKCQAPPSSSNANFFPDSRNISIAGGIFTINQVVPNSDSELHPQSGQISKFQFQIYVLFGSSGHKWWANNRIAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMM2</accession>
    <name>A0A9P6EMM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_848612</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMM2"/>
    <dbReference type="OrthoDB" id="44789at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000024">
        <property type="entry name" value="Voltage-gated chloride channel, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF6">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="587"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9531719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="744" mass="81841" checksum="7CFF57DFE3476E29" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMT0</accession>
    <name>A0A9P6EMT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMT0"/>
    <dbReference type="OrthoDB" id="10050400at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="420" mass="46297" checksum="DDE3E9AA7B1F715B" modified="2023-09-13" version="1">MHALRNTSKKINRFLPLQRLTSPRRRLPNGVGGRTYSAGPGCSASGKALSPLFTGVLVFGLGVTAYGIYGLYDTLTMWPPEIKPDLRSGLLAKRKDNLEDAAAFLARAWESTKRMSLEAFGSEPLLKTTGVAISLAGILEESKQWDQAYEIYKDALRYMANPSLIPEGSRPAELNAKLLMTFSVAERVRAISIAYRLGELAQELKKPLEEEEKWLSWAVEALLKTVLQVPRPLSQPSSGSQLDVYHRMEDLELPSWDAMQSLAAPFEALGSFYSRTGKIDFAMPLYLHAVSILIPSDSYSSPEDRCKGAQLMGNIAELVLRINPGKNLPNDIISQAESWTRKGLETTVAARKEAGSVKHAECEVVYAALLYNFGMIRELAGDKEQARKFLNGSLKQAKAIGMQEGIDMVQEGLKDLEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMT1</accession>
    <name>A0A9P6EMT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="13">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_83749</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="13"/>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMT1"/>
    <dbReference type="OrthoDB" id="2525337at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF17">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 13" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11 13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040362501" description="AA9 family lytic polysaccharide monooxygenase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="15">
        <location>
            <begin position="267"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9531733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="31923" checksum="3C99873B672D1B95" modified="2023-09-13" version="1">MQLKAFVVLASVLSTALAHTRVWSVWINGVDQGDGKGQYIRSPPTNNPVKDITSSAMSCNVNNQAVPKVVSVRAGDTVTFEWFHDYRNDDIIATSHKGPVLVYIAPTSSNGAGSVWTKLFHAGNDGSWAVDKLLNSKGHHNVVIPDVPAGDYLLRPEIIALHEANVPYSSNNIRGAQLYMNCIQIKVTSNGSKTLPSGNSFPGTYSYSNPGIVFDIYAKGADMTKYQVPGPSVWSGSSGGAITRAAIVTNPTPPSGGGSTPAPGNGQTAALYGQCGGTGWTGPTLCAEGVCKAASEYYSQCVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMV7</accession>
    <name>A0A9P6EMV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMV7"/>
    <dbReference type="OrthoDB" id="3017048at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="125" mass="14420" checksum="01E8B529106A8024" modified="2023-09-13" version="1">MEHVSKVIATRKAQLDNAKARLAAAESSVRDGEIKLRERRKEEEILQKKIELAKQYNQASKELLLVLQKLDGSKKRLAIVEDRSKRAESIVQSLLSQAEEFELKYRETKKNYNDLLYDLSSMGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENT1</accession>
    <name>A0A9P6ENT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phox homologous domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_848143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENT1"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097576">
        <property type="term" value="P:vacuole fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15858">
        <property type="entry name" value="SNARE_VAM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000058">
        <property type="entry name" value="VAM7p Vacuolar SNARE protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="5">
        <location>
            <begin position="309"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="372" mass="40729" checksum="BEC04F0E66D84065" modified="2023-09-13" version="1">MATAIQSIFIRGHEERTQPKTHIVYRIDIQAHVRSWQMWRRYSEFDDLHTELCKSTGSNPPEGLPPKHPIKSVFGVGRKDEKVLEERRAGLEKYLRAILSATDERWRETYAFKDFLGVPSGRHAGAGAASSSLATHSDTGATQFTSSTWLDEHTELQSRLRDVWADVHKRDALSNQGDVVNAHKANVGAKAKLAGVLSRIGHLGKALQELGMAGMSEGELQRRTDMVARLQDDCEKLGKVVSVARQAASRAAAGSGGVSIGKTFASDADRDALLGGAATKPARRVFGEKPKETEATRPLDNVGLLSLQQQQMDQQDNQLAQLTTILQRQRHLGEAINAEVAQQIEMLDDLSNAVDVTGGKLQSAKVKLNKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENZ6</accession>
    <name>A0A9P6ENZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_785312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENZ6"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044715">
        <property type="entry name" value="WDR86-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44489">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44489:SF11">
        <property type="entry name" value="WD REPEAT DOMAIN 86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="73"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="122"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="389"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="405" mass="45049" checksum="C3EB5635906ADCA5" modified="2023-09-13" version="1">MVESENFLVSEAQLNLGQARKEKAQRLKGVGEPIELLGKPLSIDIHDGIAWIAENTTVVRKLDLETGKTLKVLKGHTGPVASLAFCPKQPGDKKREIIITGSWDRSIKVWNLATQQLISTTPNAHLDFVKSLHVFPKLGLLVSGGSDKIIRFWDISNPESREPLRNMGFISSHTRPVECLDGHSTSDDTASLYTGDTMGVIKAWQLNKEKDSTPPRWTATLKHTYDHHRTRINELRYGNGYLWTASADDTAQVIPSTPEDPSATLAKAPKPLVHPVAVRALLPLDLTDLGEPYLITAAGDVLRTYDVSTIDQPELLGQVDAHWHDITSIRLWNRATTGEDGKTRVEPWIVTTSLDRTIRKWKLSYLLNPPPPLAIIANSNLQPVPEEAALTEEEERELAELMEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP61</accession>
    <name>A0A9P6EP61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1479-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_847242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP61"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="432" mass="48495" checksum="B22E68684A4D553B" modified="2023-09-13" version="1">MQLGPKFAELKATIASSYPNFEANVTNAWAEILAESDKTTKTIKEQGTEYVPQVSFTDLPNLSEDEIEKIRRRGTVVIKDVVDDKQAAAWKDELKQFIQTNPSVQGVPADDPQFFELYWTKPQVEARSHPNLLAATVWLSNLYHFQDKESASKFEGVNVNVPLTYADRFRIRRGGFPWAFHPPHVDGGTIERWEDPTFRGCFREIFSGNWRAHDPYELEARLNARSSLYGRPNQSSIFRTFQGWLAMSEIAPTQGTLKVFPDVFLSNVYTILRPFFTPLVPVDSSEIFDPKNWKFDLSTSEFHGISPRDGGFLGPRPTPESHPNMRLEDTMVSVPKVKPGDAVFWHCDVVHAVESEHTGTGDSAVMYIPAVPLTPQNLQYVQSQKESFLKGQRPSDFPKGPDESGFVGVAGGADITSKEGLIAMGLESYSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPK2</accession>
    <name>A0A9P6EPK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">3-hydroxyisobutyrate dehydrogenase</fullName>
            <shortName evidence="9">HIBADH</shortName>
            <ecNumber evidence="3 9">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_847718</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3 9"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPK2"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000006">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="10">
        <location>
            <begin position="22"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="11">
        <location>
            <begin position="201"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="35184" checksum="AF0E7EC2C568A70B" modified="2023-09-13" version="1">MRPTLRTLQNASKAMQRPTSTSFIGLGRMGYQMALNLFSKQHLNANEASFIVCDAVPEAAQAFCSEFTSQYPEAQISIASTPAEAAFASSKIITMLPSSPQVKSVYNESIIPTLRKLHATSSADTLCIDSTTLDVSVAREVAASVVDTGAQMIDAPVSGGVSGAKAGTLSFLVGGTEECFIQAQPVLSLMGGRIIHCGPSGAGLAAKICNNLVLGVEQIVVAEAMLLGQSLGLNPAVLASVINSSTGGCWSSSTNNPVPSALPDKSPPCERDYEGGFATVLMLKDMGLASHVAEQYKSPLPLGEAAKEIYEEVAKTPDLANKDFSAVYRFLQQQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPK5</accession>
    <name>A0A9P6EPK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPK5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="34372" checksum="090DFE41595DF208" modified="2023-09-13" version="1">MKHVKGERNTVAQENCGQLGIEADIEPRQLTQAQGPFEEKPIPSSLPGPPTIPATVFPRRQPKTGGLRFVTETKAHMAVDSFFMDAAMMLSPAATVPQVEQSWLPPRKVVGARRNVAPSVAKIQGRTDRSSRIASASFSDDSDMDEVVIPSLKTDIVQEPVSPPMAGDSTTAAGSASSSKNGILSVRKNESKKEKKKSEEDEFEEFMKERKDKAKKAAGMPVVHPQPPTAIQPTSTSKGLGTSASVNETAITPEVIEQPMETLLKLSNTELTAQFSTRRIRGLPVKGSNRSTITAPQAGQHLQEVRHSCSRVVISKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPY5</accession>
    <name>A0A9P6EPY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family group 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_846434</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPY5"/>
    <dbReference type="OrthoDB" id="38531at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF2">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="719"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="747"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="793"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="847"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="14"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="523"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="907" mass="102469" checksum="56163F64833A5F18" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQD5</accession>
    <name>A0A9P6EQD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI inositol-deacylase</fullName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_317353</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQD5"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056824">
        <property type="entry name" value="PGAP1_TMD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25140">
        <property type="entry name" value="PGAP1_TMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="629"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="703"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="749"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="837"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="11">
        <location>
            <begin position="84"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase transmembrane" evidence="12">
        <location>
            <begin position="698"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="955" mass="105070" checksum="87FBCDBCA6084667" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERY9</accession>
    <name>A0A9P6ERY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERY9"/>
    <dbReference type="OrthoDB" id="3222065at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="35182" checksum="FFBC80624D9BB3EF" modified="2023-09-13" version="1">MGPQNPDNLPIDNVIQGTHGQLVAFFFFHGWTTFFGLPILLGIMVFSKRVQRHATFINLSVAFLVIGLASNLLLLSGKAFGPEPSRMLCLLQASLLYGMPSLLSSCALMVVLQMFFLIRAAAHNQEFKGEDHVGRLWSMINLPWIVYSVFVLATAVIGSADVSVVSRDRRFFYCSVDVPPLSNFILIYGALMLLTSWGFIVWTIVLLYRRWNLTSVVSIDLNFPIRIMLFGIYIVVAFSLSLISIPTPSTPVPDLVIATASTFFILIFGTQQDIVSVICFWKKPESGLRVDLTTGQIYDTNPVFESKPTSRFDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESA7</accession>
    <name>A0A9P6ESA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_420329</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESA7"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04370">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000199">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAH" evidence="12">
        <location>
            <begin position="117"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="229"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="353"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="389"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="957" mass="106777" checksum="149F7F01C7E4DCB8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESG1</accession>
    <name>A0A9P6ESG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_782011</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESG1"/>
    <dbReference type="OrthoDB" id="2146at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034719">
        <property type="term" value="C:SMN-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000023">
        <property type="entry name" value="Small nuclear ribonucleoprotein G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037188">
        <property type="entry name" value="U6_snRNA_Lsm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="4"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="8558" checksum="A1FA36B331C96541" modified="2023-09-13" version="1">MSKASQPELKKFMDKKLFVHLQGGRKVSGVLRGYDLFLNLVIDDAVEESTPAQKHQIGTVVIRGNSVTSMETLEAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESU3</accession>
    <name>A0A9P6ESU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_843841</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESU3"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000006">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000004">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="17">
        <location>
            <begin position="300"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9534193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="628" mass="70883" checksum="95584E39570F155E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESV3</accession>
    <name>A0A9P6ESV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_830927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESV3"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="38"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="57194" checksum="1BEFFD8512C1C7EE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETV5</accession>
    <name>A0A9P6ETV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_924921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETV5"/>
    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="548"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="685" mass="77015" checksum="AD42501ACC61B05A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUM5</accession>
    <name>A0A9P6EUM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUM5"/>
    <dbReference type="OrthoDB" id="289721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF15">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 12 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="394"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="684" mass="75964" checksum="B93D7E8E8A01E261" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI31</accession>
    <name>A0A9P6JI31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_747079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157968">
        <property type="protein sequence ID" value="KAF9521986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI31"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9862" checksum="7C84DEBD8A3094B6" modified="2023-09-13" version="1" fragment="single">HEPIKVPAHSSPFSMLEHEAVLWEALAMMNNEEVMPSRYGIQAEEWEGGAYPTTEDLVVGGSTDCIELSVEEWGPWAERWCRALFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIL8</accession>
    <name>A0A9P6JIL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_777334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157953">
        <property type="protein sequence ID" value="KAF9522258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIL8"/>
    <dbReference type="OrthoDB" id="2794314at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="13510" checksum="202FA4A52626C39D" modified="2023-09-13" version="1" fragment="single">EGTTNLLNASKACDLKSGVVTAAAKSGSSSAEKGVSYSPAAHRALMVMRSAKYARPFNSYTDEEYKQEVAMLRPGATVPHPSTISRDLKHVYLQMSQHVKNHFLVNGLVLFNSRRVLINYARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIP9</accession>
    <name>A0A9P6JIP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_116572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIP9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="52" mass="6032" checksum="073B8D6D8418C815" modified="2023-09-13" version="1">MLLCVHCLTFKFPKHSKLHFALILFQTCGPHIFGCVLMIGINRMKMQQEIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ42</accession>
    <name>A0A9P6JJ42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_864200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ42"/>
    <dbReference type="OrthoDB" id="9986966at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="29662" checksum="FCCF701A1E0AE034" modified="2023-09-13" version="1">MAAPTIGKWYRLTNAYTGAGLALDVVNDAGTSSSGTLQMASAGAFSGQYWQLEYNPASSTSTYALFTQFLGETKRLDVYGDDATKPHLAAGGSYSGQIWTIAAWGDGTFRLSNAFSGSNMFLDVYSDTQIPFLEAAEHSGQHWTFTPLDGQAAAAPSPGATTHVPSTVTSSGASNTSLPNSPPQPAASDHSSPSGAAIIGSSKKSSVNAGAIAGGVIGGLAVLGILVALAFYLRRRRNRAAGVTTNHDPPTSPVSKETYQHNGQDGLASTYQAPVLNNGDGGYFGSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ73</accession>
    <name>A0A9P6JJ73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_864171</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ73"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000171">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="74"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="534" mass="57768" checksum="C9A8DF1619779F13" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJB8</accession>
    <name>A0A9P6JJB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_63361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJB8"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF121">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="255" mass="26053" checksum="C9D5AE7035390513" modified="2023-09-13" version="1">MSVDTIRQVAIVTGAGQGIGKAIAIRLAADGFNVALNDLPSKSLEVASVASLIHQTYQRKAISVLGDASAEEDVSTLISRTVAELGGLHVFVANAGIYQAKSILDTSVADWELVMGVNARSVFLAYKLAATAMIKQGAGGRIIGASSLDGKQGSGNAPAYSASKFAIRGLTQAAASELAKHKITVNAYAPGFIQTPMTGAAAVEAITAKGNTPQAPNMSLGGPEDIASLVAFWASPASSFVTGQTWIVDGGTIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJG8</accession>
    <name>A0A9P6JJG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJG8"/>
    <dbReference type="OrthoDB" id="3256331at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="31"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="24366" checksum="FB3E3FDD73B23AB9" modified="2023-09-13" version="1">MFFRKSKSSGSQETLVDERAEPITMHFSNSSPTNTVVSRRSKPYMTISTTDSRTEVTHSPSKELLVLIKYKTFEAGTVQFSRFYQGKSLVMSEWLKKEKCKAWKRWVFETDVGYLAWRTDPQHPLVLCRAEDMHHPIIRVKERLPVYPARSSETFLEMAIQQGHGLETIPEIILASYCIVEQLRAEKASLSKGLFKGGKDSQFLAAHAIGFGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKI9</accession>
    <name>A0A9P6JKI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_862091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKI9"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="872" mass="97017" checksum="47A58AD5095CF04B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKW4</accession>
    <name>A0A9P6JKW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_861397</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKW4"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="451" mass="48139" checksum="2145F7114227FF08" modified="2023-09-13" version="1">MTPALDLLLTTAGGANGHHRHVNGHNGVNGLKKRVDGFGTRAVHVGSEPDPSTGAVIPAISLSTTYRQESIGVHKGYEYSRAGNPNRNALEATLASLEAGGAYGLAFASGSSTTATVLQSLGPNAHVVSVNDVYGGTFRYIRRVAAENQGLEATFLDLENATDEEIVASFRDNTKLIWIESPTNPTLRLIDIKRVANLAHSHPSRPLVLVDNTFLSPFYSSPLLLGADIVLHSLTKYINGHSDVVMGALILPESNADIAQKLRFLQNAIGAVPSAYDSWLAQRGAKTLHLRMKQHGLNALAVARALESASGVEEVIYPGLPGKTASSKRKNELAWRSLSAHARKFIGAEEGDRPPAEGFPFSGMVSFRIRGGQTEADRFLTSTRLFTLAESLGGVESLAEHPAQMTHASIPPAERALLGIGDNLIRLSVGIEEQDDLIEDILQAISNATGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL77</accession>
    <name>A0A9P6JL77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL77"/>
    <dbReference type="OrthoDB" id="2940489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="10313" checksum="104DCBF52BE48163" modified="2023-09-13" version="1">MPFNIRSGVSHSRDIKVFVSKYSVDGNDSWYPLAPNFNDADKAHWQRNGWEVVVFKEGNVRRGWYIDCSNKTVDITFNGFSQDLGIVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLH7</accession>
    <name>A0A9P6JLH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_551043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLH7"/>
    <dbReference type="OrthoDB" id="2593559at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="69"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="276" mass="30682" checksum="77278AFC6E308241" modified="2023-09-13" version="1">MIIEPADSSSSQTSPKMKLPDNPPTYSEAFRSATINSARTASSSHSRHTAPDKNLPDRPANLHSAVDQVHIYNRKSEIKGVFHVDPLIPLLDIERRHKHHHKGHGHSKHDPIPHASFRTRHSEIDISLATNGDFRQASRANVSVSNMSKDLKITLLPAEPSQPRLALNAASKHGTVVLLIPPNFSGIVRMQTHKGSLEILPALAHRIKIAKRTEHEIIFMRNGDEDDCPEANYCDLTSRTGKIVVGLRDQDQYVPAVGFWKKFGSSFSRKDSDNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLI9</accession>
    <name>A0A9P6JLI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_797510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLI9"/>
    <dbReference type="OrthoDB" id="3234974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="277" mass="29905" checksum="57011AF26CD0C2CD" modified="2023-09-13" version="1">MSADSQFMSIAVALGTPSKSFEEVRVEDYLRFYQTTGGHPPPVPQEPTDEFQRKTLNLPPLFKPQTNLVPPTTSSTANPVVSATDGSGLGSTSTVATLFSKPKITNPTDIPLGQEFKMHIIASERYQCIVCMPEYEGFSTEELRYYAYMRGNINSPIPITMDPFVPLNKDSPAPTPVSNADGVSDENLQSQCALPDFARHSPEELRVAYLLYGREMTSAELLGPAAPTITPAATPVAPVPTRPSLFGTPTISQPVPPPIIATSGPAISTPKFSFGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLN1</accession>
    <name>A0A9P6JLN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_909233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLN1"/>
    <dbReference type="OrthoDB" id="2591449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="698" mass="74042" checksum="71BEF44E4CFD784B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLR1</accession>
    <name>A0A9P6JLR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_797211</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLR1"/>
    <dbReference type="OrthoDB" id="244190at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15859">
        <property type="entry name" value="SNARE_SYN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000060">
        <property type="entry name" value="SNARE complex subunit (Syn8)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="159"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="94"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="28344" checksum="0C9BA324C9076181" modified="2023-09-13" version="1">MSLAKLTAVSTKTLSLLLERQRLSTLPSYSTNGSSDNPFSNGSSLHYPQIKRNLNQLREGILALQAKEGSDSEAAKLLRNQYDRMRGMLWEEERTEIPSLEKEPSPTPSPEPEPTKPVYTHSTNRDSLLSQPSFAPYTDDPEQGSVEPPEPGTMLQTQRFMMDEQDQRLDVLSQSINRQHHISLQINDELDTHHGLLQELDTDIDRTENRLRKARRKLDTVAKGIKNNASVVTIGVLIFILLILIIRYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM11</accession>
    <name>A0A9P6JM11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM11"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="15585" checksum="A5924B1BF8485D33" modified="2023-09-13" version="1">MALPAPTPGGHSESSSVVDSSTGLGLVGLKISDVARLTSVGYRARSTGVWKGDGGTKEDSGGWCEERKKGCRRASEYPMDSGLVACGIRAPAATRRAEENSVLFVASVVDAGTTATRRQSGEGATISDGWKNGLDDEEMHQVEVGEPSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF4</accession>
    <name>A0A9P6JMF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF4"/>
    <dbReference type="OrthoDB" id="3268696at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="935" mass="106648" checksum="E8EFB9FFD66F1FA1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JML9</accession>
    <name>A0A9P6JML9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein 135</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JML9"/>
    <dbReference type="OrthoDB" id="4021778at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="649" mass="71236" checksum="8A3F7EDC7E162277" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMR7</accession>
    <name>A0A9P6JMR7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_507555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMR7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="82" mass="9778" checksum="883B5B2226D68083" modified="2023-09-13" version="1">MRTQWRLSNASGLKCGLFWIQYLLLYVSHVTLRCKTVEHLYIVLVRHSTTVALFESYFLERNPTVAIHNSHILPQLHSHFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMX9</accession>
    <name>A0A9P6JMX9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_794417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMX9"/>
    <dbReference type="OrthoDB" id="3258172at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="14596" checksum="278A2018F1AA2D8E" modified="2023-09-13" version="1">MPQQPASATRIKLCDINSDLIGRKLRVAGRVLSYDVNTGLIVLVDGKEAVLVDISLALDFHSKVWATDRLSTIMAIGDLESSDAPLEIPSTASPHVLALKISNQLVLRAILVIPSPNLDLGLWKAVLDEEEESQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN00</accession>
    <name>A0A9P6JN00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN00"/>
    <dbReference type="OrthoDB" id="3145912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="284" mass="32164" checksum="480CD53B6B1D8DB4" modified="2023-09-13" version="1">MLQEHHEIREPRLPTELEREIFELASRDEPSTRYSLIQVAKRVHKWVEPSLYCIFIICEGTDVIPSSLFLSSFKERLAVGGSTAIARQAKFVRHLMYTGQDMSSVVDLIILCTNIIDLAVWTFPGVPNTSLTTLTTFFDALHLKRLSVSAELIQLYPHCLSSLALSLTHLDCFGMHSPFWDDGWKILNVSHLTHLVVAGSNIRPIITAILKESKTIRLVINAQDNIPSPDALEGPWYTKDPRYVFCKYPNPPTACWFKGTNGGDDIWVLGEEAQRRKIQRLSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNS2</accession>
    <name>A0A9P6JNS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YT521-B-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_870165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNS2"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061157">
        <property type="term" value="P:mRNA destabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF89">
        <property type="entry name" value="YTH DOMAIN-CONTAINING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="512"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="742"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="759" mass="83201" checksum="918FE495B76A84BF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPC0</accession>
    <name>A0A9P6JPC0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPC0"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="25227" checksum="548571665745F85E" modified="2023-09-13" version="1">MLLTFPSVWRNCYNFQNLLDMSPHLASFVRCLELFDSPIGIFPVHTQWRTEERGIIHNKVLHTWLPLLQKLQALTLTIATSTDLRSTWTDMPLPLVSAIRSVVQYPSLVHVDMEGTSIVSILQNTSSTVKHLVVHTGDKSFDLEWLGAALNCRLICWKHCLKLTCNPHQFESGRTCIYSLKSNISFCRLKKLVVSIEASLLLDRTRPHVLTKDLRGVGWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPN5</accession>
    <name>A0A9P6JPN5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_855596</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPN5"/>
    <dbReference type="OrthoDB" id="10250970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2690:FF:000003">
        <property type="entry name" value="Splicing factor 3a, subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="25409" checksum="BCC6F5FF51A96123" modified="2023-09-13" version="1">MDYQNRVGSKFGGGGVAGASESNVDRRERLRKLALETIDLAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDAKETQLTIAPAASTTQKKVFLKIGRPGYRVTKVRDTDTGKEGMMVQVHLPQIKDDVLPRRRFMSAWEQRKEPPNKAYQYLIVAAEPYETIAFRIPAREIEDEADDAGYWNWSHWDSDTKQYSFQFMFRLPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ57</accession>
    <name>A0A9P6JQ57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_854754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ57"/>
    <dbReference type="OrthoDB" id="3066029at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="34"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="466" mass="50431" checksum="60C5454F2E1245FC" modified="2023-09-13" version="1">MASSTSEETPLLQDVQKLHEQVYQRFSPARKNAILVMVSLTGLMPPFVSGTFTPLIPQVSKDLNASAALVSLAVSIAIFATSIGSMIGSCYSTLYGRRPIYLLGIPMLIIASFGVAASRTIHQLLFWRFFQAMGSSPGLTIGSAVIGDIYKLEERGAAMGIFFGALLLGLTLAPVAGGVVAHYSSWRTMQQAVGVWGIGVFVYMYYAFPETFHPGQRGVDKMDPGAHPKWRPVILNPLKPLWMLRSPNLLFVSTAAFTGILADYVLQIPIAYTIGVKYGITNEALIGACFIPAGVGNVLGAIYAGRLSDKMVIKWRAKRNGVWYAEDRLRVTIPGALYYVPLSNLMSGIFVTYVDGPVGLTLNLFCLFLNGFGVDVVLGPSAAYFVDSMHSRSAEAMAAYSGFRQVLTALTVSLIIPMVEKYGVLATDTSSALLAWIGWLLLWITIQHGDRLRAVVDVGFSTAADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQX8</accession>
    <name>A0A9P6JQX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_905447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQX8"/>
    <dbReference type="OrthoDB" id="3067211at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="490" mass="54358" checksum="73D658AB23D685E8" modified="2023-09-13" version="1">MSTSDSREASSVLGMTQQNNAAGISKIPVELLADIFFHVVSHPSPSVFESTHPMAEPDSELIRSSHSTDYASCASPYAISHVCSHWREIALSSSNLWTQLCVVLPTHEELLPLLHLWIERAKDRPLELSIQEPSDQGCNGRPGYSRKLNTSRVVFDLFLSLIERWKSIDISLSHTPLEHLINPNLLSSLLSSDTILQNLESIRVSSLPRAPEHDFHSGLESRRHSQVVPLIASLLHQSPYLRNATWGNLDFVKLSEPARHTHPPSSDHASSFSQTSSLWPTSLSELTIHEVHCEDISALLTSLSSECPVLQKLCIMKSEQPRRPYASSPNNAPPPASSFLSSPWGDSQETHGIARGHVDGRLSNRPSKILLQNLNTLFLVFEDKELPAIFDAVILPSLTTLCLSSSSSSSTSQPLDETPSSGSITSRESISNSTRNRKRWSRLSAWAWCSLSTMLQRSDAKLDTLKVGGVDLCDHGRSFEVGEIWQPYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS80</accession>
    <name>A0A9P6JS80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS80"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="180"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="791" mass="89416" checksum="51278AE2C380DB03" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSG0</accession>
    <name>A0A9P6JSG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSG0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="184" mass="20319" checksum="7487A037B404DF27" modified="2023-09-13" version="1">MEWRVKEKLEEKKASKYRACHECKEAHEKCVLPGFEDIPQTIRAKASGTAPAKKKTKMESTKVASPEVVDLLGEILEVIQRIDARTLREVERNSKFQKVVLKELADIDEKNSEYFVFMNETSKRMAAIMQHMGLPVTKRKGKGTESGVPEAGGSKGPETKEGEGKGGNEGEGKGGERNEAGISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSH3</accession>
    <name>A0A9P6JSH3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_850472</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSH3"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000010">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="55"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9530525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="121" mass="13855" checksum="ED7C1F89D66BAF45" modified="2023-09-13" version="1">MAEADTMDVDMQQTTTVATTSKKKESGKESGKARFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIDCQANQVSATSEECNAAWGICNHAFHFHCISRWLKTRNVCPLDNREWELQKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSP3</accession>
    <name>A0A9P6JSP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_123964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSP3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040209780" evidence="1">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="184" mass="20846" checksum="01DF3237E1B52074" modified="2023-09-13" version="1">MLWPSSVDLVSLLLNFTSCFEGIRIDCGIASEGPQSNPEVCQFITILPKQSKHRKLGARCSKVLRLRTPWIHVFDSLISDPDKPILPLLRKMLAHLFWVNLLVGPLKRHPSILPNLEAVAYILDDPAKFKRMDSEFRSISSAFSVRQLSLTICLLSLQGISEWLDKHSENAERTCSIMTSFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTP2</accession>
    <name>A0A9P6JTP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_891647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTP2"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="28768" checksum="CCD95829938B65C4" modified="2023-09-13" version="1">MTITFYDVPSIVPGSSWSPNTWKTRFCLNYKGLKHKTEWVQWHDLESIFVKIGIPPSGKDHLGRPRYTVPAIFDSTTGIYLSESFEIAQYLDRTYPKTPMIFPNNTTGIQRGFHMALSPLVEPIGPLIIPVEGTKLNPASQECFQQKMEGHFSKKYAEIELAEEDRIEMWVKLKENFVVVHEWYSLGNNPGPFILGETPSWVDFVLASIFLWAKLIFGEDSNEWKEIETWHESRWKSLLSSLSEYQVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUK6</accession>
    <name>A0A9P6JUK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Meiotic sister-chromatid recombination aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_845420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUK6"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07098">
        <property type="entry name" value="ALDH_F15-22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="100"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="628" mass="70324" checksum="8BE0310C2A088393" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUY6</accession>
    <name>A0A9P6JUY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_804982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUY6"/>
    <dbReference type="OrthoDB" id="2628419at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="29612" checksum="7F4AF0C801BE5618" modified="2023-09-13" version="1">MASLNFSISTATIITTSLHPTNSLLAISAGALAAQRAPYITTTISSIAICLTLLIVLVYLAIFSWAYRAANQCPKALNTRFGVWLQRYAPGGYAFLVLSSLIIVDIAGWLVLQYRFNHNYPRSAVRMACHLLLFASCWTFLTALAYTVLFLYPAFSKHPISSIGAQVVWLFTTLLFWIIGAGILNGSVPGIIDKSQCEGIVYCFQIRLLFGMAVIESVLITVAIVAIVWLGWQSTRLAVHRTSLRPLSMLPLSTILEAFDRPKEFNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV04</accession>
    <name>A0A9P6JV04_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_845300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV04"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040485976" evidence="3">
        <location>
            <begin position="21"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="239" mass="24001" checksum="CC9D043F8D78F4C5" modified="2023-09-13" version="1">MFAGLLACTLLALSLPLTIAGSHNVPHRRHHAELAKRQGTNARMTFYNVETGQEVACGGFGKNSDATVAVSLSIFNKAEHCGKSISITFGGKTVPATITDACEACPPDGLDLTEGLFSQIADQGLGVIAASWSFGGGAPPPPPPPPPPPPPADPAPAPAPAPAPAPAPIPVPVPVPEPVPSPPAQDPSPSPPPPAAVPTPSASASVSASSAAASAFPSGPSSCKKKRSLRRRQQPSNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVG3</accession>
    <name>A0A9P6JVG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVG3"/>
    <dbReference type="OrthoDB" id="192748at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13642" checksum="7322CBC8EAFE3121" modified="2023-09-13" version="1">MQISKVWLVNRTISRLSNAQSSTGLRPTFPQSERKKMEGMGEDFRPPWVYVGTRLISFVVIPAVGLYSVFLYDFGTQNHVFTPVRRWTANAFSSFFTLSSEEKKLLQQEQDVGQGYTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW39</accession>
    <name>A0A9P6JW39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CobW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_782211</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW39"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="9">
        <location>
            <begin position="43"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="10">
        <location>
            <begin position="347"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="421" mass="45935" checksum="8B14F296133167FE" modified="2023-09-13" version="1">MSFNDSDDDVPTLVETLNASTLDPSADKQPESSNAKPVSAKVPLTIICGFLGAGKSTLLKRILTERHGYRIAVIMNEFGDTADIEAKTINVSSADDPTAEGSEEFLELANGCLCCSIKDVGVAAMEKLMLKKGAFDYILLETTGLADPGPIASMFWTNEEYANGLADIVLDGVVCVVDGVFGQKQMAEDHSTDELRIGESLRQIAGSDVVLLNKIDLAPPESVAETEQLIRKVNPAAPIYKTIKGEIDLKYIIGIQAFQKPPSVDEAVTPNSHVHTDDCDHDHDEHDEKKPPTHYEVRGISSLQVRCGILDQAHIDKLDAWIRNALWENRVSVRSDEKITSDPVTEVQVQILRAKGAFTSKEGKHFVFQGVRSIYEISELERKAPGVGGDTDVDVPEEGKIVLIGTGLDDRVRKSLESVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWH7</accession>
    <name>A0A9P6JWH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_755201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWH7"/>
    <dbReference type="OrthoDB" id="3166422at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="21822" checksum="DF11823C71028AF6" modified="2023-09-13" version="1" fragment="single">YQHPNGDHYYFNPGLRLLTTDDIHDPIVLGYIVDARDDIVQQLVTANLPADYELVITDTSEIAATIRIYSRSAGQAYLWTEENGRYMIKVQHFWTFVAEFPSHHLDLPPNAEREFAHALETAKTAIASGGVFPFTSSEIDQIVARFETLKALRSEGQNTTPPLAWLIGMVMPLGAVNRRVNDHNLEAMMNGLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWT4</accession>
    <name>A0A9P6JWT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_901254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWT4"/>
    <dbReference type="OrthoDB" id="2970010at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040372203" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="11759" checksum="9BF451CF19122B37" modified="2023-09-13" version="1">MQFTSTFTALVAVALCAAPQALATVSFNVAPAGTVCGHGTTITCTPSPGHPCKGNFNPKQASIVVTQAQGNCHVSLYPQNNQAGGVAQRLNTDTTGTCVFTSTATWQSYGIYCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWY3</accession>
    <name>A0A9P6JWY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sterol 3-beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CPB83DRAFT_842264</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10261837at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000303">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000391">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000029">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="12" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="21">
        <location>
            <begin position="334"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="521"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1367"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="530"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="610"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1388"/>
            <end position="1397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF9535744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1452" mass="160176" checksum="4B111B1128CB6528" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBP8</accession>
    <name>A0A9P6BBP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_778711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158059">
        <property type="protein sequence ID" value="KAF9521458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBP8"/>
    <dbReference type="OrthoDB" id="3214502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="118"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="550" mass="62316" checksum="AFFEBCE99BF1A36A" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC73</accession>
    <name>A0A9P6BC73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158091">
        <property type="protein sequence ID" value="KAF9521384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC73"/>
    <dbReference type="OrthoDB" id="3263746at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="748" mass="84007" checksum="884C17B48A6C0642" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2I0</accession>
    <name>A0A9P6E2I0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158173">
        <property type="protein sequence ID" value="KAF9521274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2I0"/>
    <dbReference type="OrthoDB" id="2976650at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="67774" checksum="B5572CA8353E641B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E438</accession>
    <name>A0A9P6E438_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6589 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_840713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E438"/>
    <dbReference type="OrthoDB" id="3033641at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046496">
        <property type="entry name" value="DUF6589"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20231">
        <property type="entry name" value="DUF6589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6589" evidence="2">
        <location>
            <begin position="266"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="407" mass="45510" checksum="41581D847D00099C" modified="2023-09-13" version="1">MSHRQKRVAGGKENYKTEGSTKLASSSLTKGDKVRVFFGVLKFLEWSYGEALALTATPVSNLKLEKNSLPSSKVASTVSMEITPISGVQITATMQHFFNVIHLWFKHPFGSSQRNSGNMYSTAVPYTELKHVWPVLTSFVVQVVKQKLVREGEKAISPESGLYVSLSGKKPSSQKLAWTDIGSATFGTVRNIIKQHQPLTLILVSAIASRPPRVRNNVVAVRRTQPVPLNKLNIGLAATYYKVNLDGVDVAVFDLDQPAPKGSLTRASLTVNKLCNFVDFKHIKYVCILQWIGNLIYHIPHLKHLGPELSLQYRTRAAKQRLKVVPAKVHPLASSSRNETITTELKDALLDFLAQTGQQPEAFKCRLFPIGGDGLTFEKILQLKDYLQFHMNDVEALRIHIWYCVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E463</accession>
    <name>A0A9P6E463_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157957">
        <property type="protein sequence ID" value="KAF9522165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E463"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="12"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="418" mass="46543" checksum="9646F70495D0C5E4" modified="2023-09-13" version="1">MVRLTNAGKQALDRLVAEAAADPSIASFVFGVGTADGEIYFHGGGYRIQDEPLSGLVNPDSVFRLYSQSKTITCVKCSYSIAALHLIEQGGLLESDPVSKYLPEFSNLIVLSDPLADNPQFSPAKTTMTIKHLMNFSSGLSTPSKDPTQYAAKLYPEYLTAHDELDPIGGFIKVIKRGYPGIPLVFEPGTDFAYGWSIDILGFVIEKASGKSLENYIKKHICEPLKIKFSFYLDNEFHQRLVALVKKNESTGRLEVVEEDYLYNIEPSKVFCHLGGVGMYSSARDYLKLLRHLLEINKGVAQNPIISASTLSSIFQPALSDKGQRSLGLICQRDPYMPQDEGHWSWSNVFSVSLQDWPGRRRKGTGGWGGWPNLKHFVDPTTGIAVIFETQILPTFNPDVLRYYSEFEKVLYAGLEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E486</accession>
    <name>A0A9P6E486_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_899871</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the polysaccharide monooxygenase AA14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E486"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054497">
        <property type="entry name" value="LPMO_AA14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22810">
        <property type="entry name" value="LPMO_AA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040411693" evidence="12">
        <location>
            <begin position="19"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9522148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="42575" checksum="CFA4C0FA9D172A70" modified="2023-09-13" version="1">MFALLSLALLSVVVRVSGHSAFWHPSMYGFNVTDKTYPYDNRPVAPIKNMDFKTWWFHNHLDHPPNGGDFFELSAGKPATAEIACNKGATSFFASADGGDIRNPSNPNDPCPGSPSITYHTKSPDDLQGCALAIAYKSDVNQVQPEDFTVFSVNHTCVSKRFTDFQVPARMPPCPEGGCTCAFFWVHSPLTGGEENYMNGFKCNVTNTISNIPLATPKVPRRCGADIENQKLQASPANCTWGAKSPIYWYNKEKNNMFEGDFSPPVYNDKYNFIDGAQDDIFADSYLTIPDPSPSADMPVLADVSVKLPLNGTASVGSIPSSPASPASPFQARGCGHSATLAKRDVDELKDVERDWKTFTRGGLKGMAQRRRSLKHVSRRNLWRMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E500</accession>
    <name>A0A9P6E500_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_864143</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E500"/>
    <dbReference type="OrthoDB" id="9985428at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF1">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="3">
        <location>
            <begin position="102"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="671"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="695"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="717"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="728" mass="79838" checksum="ADB56A53E17A78D3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E569</accession>
    <name>A0A9P6E569_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_776675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E569"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="78"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="6">
        <location>
            <begin position="172"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="5">
        <location>
            <begin position="176"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="33762" checksum="560CFFE66BE71D9D" modified="2023-09-13" version="1">MSSAAVGEDLAGGLETKTQLKHSSDIDLDYGDPLCVTEYQEDIYKYFKKLEACAFYFSPDFMDKQLNIDWNKHCILVERMIQLRSEMKLLQETILLAVNILHRFLSARAVSTDKVELVGLCCLLIAIKYEEVYVPSISLLLSLSMDTSSTKFEIIEGEKYILKTLDWDLRASGPLSWLRKASEADDYDVKSRNLAKYLIDISLAEKKLVRVVPSLLSASALWLARVVSNRGTWNTELKHLSTYSENELLPVASIMVDYILVQPPPHSELYNFYDTKKHFMVILDYSSNTLNPPPSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5F3</accession>
    <name>A0A9P6E5F3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_776472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5F3"/>
    <dbReference type="OrthoDB" id="3051935at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="15865" checksum="2AFB8390BC0AFDAE" modified="2023-09-13" version="1">MSLTGPTDKLFTVPDGTLRVHPNRDARFPYLYQVHGHPLVRADPAIQQVFVFVIDTSPLALKALLDFEDSLTVPLGPDASMEDLGLFELHDGTVVFIRERGCENPEDDVLFAWNYLGWVAFKPEIFLSLNCMMQIESVQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5H6</accession>
    <name>A0A9P6E5H6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_863863</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5H6"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9522899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="227" mass="25529" checksum="930E2811717DDAD3" modified="2023-09-13" version="1">MSEPTSSSNSTRISSANEPETTSAFEKWRRKAMLVTGLGVSEDERLANLQASHMEHCEKRKEDLMNTSPLLGFMMKHLKLAGCDVPPSNILCAPCDMTKAGGFSPDPGAVILCGGHFFSKQHMESTIAHELLHLYDHCRFKVDWSNLRHHACSEIRANNLSGDCRFTRELRRGVVAFSKQHQACVRRRAVESVMANPACPNQETAERAVNEVWESCFNDTRPFDEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5N5</accession>
    <name>A0A9P6E5N5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_69141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5N5"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="80"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="782" mass="87603" checksum="D46DB9B2F5385FDE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E688</accession>
    <name>A0A9P6E688_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E688"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="78205" checksum="528F15622774567C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6F0</accession>
    <name>A0A9P6E6F0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="4">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_862756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6F0"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040545927" description="Carboxylic ester hydrolase" evidence="4">
        <location>
            <begin position="22"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="6">
        <location>
            <begin position="332"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="39268" checksum="C6B4733E7B943A3A" modified="2023-09-13" version="1">MLSRLFQVLISSLMIVLNVEAAQNQLQQVSNYGSNPTNVQMYIYKPTGLITNPALIVALHWCNGNAQSIFTGTQFANLADQYKSFMVLYPNAPDSGGCWDVHTTATLTHDAGGDSLGIASQVRYAIQNYGVDKSRVFMTGLSSGAMMISVLAGAYPDLFTAGSAFAGVPYACFAGSSMWNSQCSTGQTSKTPQQWGDLVRSGYPGYSGTRPKIQIFQGTSDTVLSYNNFGENIKQWTNVFGYSTTPVTTQSNSPLNGWTRSTYGPNFQAINAQGVTHDIPIQHADALNWFGITGGGGTTSPTSVPTSTPTSPPSSTPSSTPPATTTTTANAPTQTHYGQCAGLTYKGPTTCEAPYTCKYLSDYYSQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6P9</accession>
    <name>A0A9P6E6P9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_692599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6P9"/>
    <dbReference type="OrthoDB" id="3037750at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="36339" checksum="BA5C271BB32978AA" modified="2023-09-13" version="1">MIYSLFFLGIPNFYIPSISVILDKVQRAEDDIHRLALVEGGGTTKEMILCDLDQSPDPWKVPHGYKDLQKSWHELVDNRTNEWVMLMTLSGMVFAGVVAFTQISGSSANPFMKNALQLSALCALTSIMGGAVYTFKFKAIRRTSMSIEWALDIRKSQGNVFWNTSLVLSLPAVWFVWSLLLCLTCILYYVLAPIPMDPEEYHSTFWHSLNIAGRVFVVGNLCSAVVQAFKVFYTFRRWRYDKLMSRLKEPPDPSSYISERLPSESSHPHFPPVQVDLENASSRRPNPSVPYSFDCTRLAGCRDAYTHGKSFMARVLPVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6V6</accession>
    <name>A0A9P6E6V6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_862393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6V6"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="107"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="726" mass="83184" checksum="A54EA1356AD625B0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7L0</accession>
    <name>A0A9P6E7L0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_877849</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7L0"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="642"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="689"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="717"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="791" mass="88988" checksum="78E11C80964F5912" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8G8</accession>
    <name>A0A9P6E8G8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_797973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8G8"/>
    <dbReference type="OrthoDB" id="5402897at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17583" checksum="5E45FE36A570AD9B" modified="2023-09-13" version="1">MSVLSFLGNVNIAIRIVDKLYPKAQLYEVDGTTSDGKPTTDPIKINKLRVVFTADEGTVLINSASWGEWNAPTYIPEPWLEDVVIPFPIDMDIVDAQAIKDKAGYTTEYAAVTLRWPLYPGTEEPYYIFSLKNHHVFVGVYTKQVFVENLKAKTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E923</accession>
    <name>A0A9P6E923_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_860346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E923"/>
    <dbReference type="OrthoDB" id="411632at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="452" mass="52711" checksum="8DE5F12F466B164C" modified="2023-09-13" version="1">MGLLRPLNSLWRGPLLLVMGTVAVFYYVVSTLHIQYTGFNHSPGEDLRLSPTTAPDYVSAKTLEGIRVLLVTAWFPVPNPQFTAEEYDSWLPNFFGSNKNHIYLYTTPEYERYLRSFRGENLTLTIDTSFASPLDIPPLKGKDELYRRILKKDRAKSRRSVELYANRHAKPFFLYNAVSRLARRSGKKYDFAFWSDAGSFRQSNVYTEWPSLHRLHNVFSAATFLPSVLSTAPDELIFIPSSKPPHTSMKFWSEEMGPIDNDISIASFFGGMPKSLDWLVRTYYVYHDHYLSLEIFIGKNQALFNSLFFLFPERFITVWANDPDAPEHLALQRQPEERFLGQCGSESPTGKLKTSTTRNVAQFTAEPIPAFNERFYYQFWLANDEERRNMAEFWIKKASEWRWWGWWRPRDQTPCQTTRPLDIETVLKSKLGDGWRSPKKSVEVPQDIRWNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAU4</accession>
    <name>A0A9P6EAU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Origin recognition complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAU4"/>
    <dbReference type="OrthoDB" id="3358956at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="49056" checksum="738D7959001E1729" modified="2023-09-13" version="1">MSSNEHLLDHFSASTETRQLGAQILRLAHVKTRPGSGRELKNYQVGLPAACMLIACEQLNTTEVTQKSAQTAACLTLKEFKKVYDIVKTILAEQEQASNYSYLGLHSDHDTDVKLDVINSFLTEVENEIMQSGYTSSNLTKCSAYFWTVNCIKPRALASTELFALNYDLSLKKFINILNMLNDHCKLIRKKIQSELKTVIQSPSKSTATSTPRRRELITNESPLKAPTSTPNDTSPVRRSSRTSSAVRDISLSPAKKSAPLPWRKVAPRELPTNDSPRRTPKQAPGTQIVDVEMDYLPETPSKRRKLESPTRLTSESTFLTALATPGSSRVLKELSYKKGGLRPTQLFPTTTTARSLKRKQDADAVFEEYVSFDESEGDVTTPRRRFRPVCLEHQQWNMLDPRLVKIWKQVEKQRTVPLFSSSKPPISRSLRLGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB22</accession>
    <name>A0A9P6EB22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB22"/>
    <dbReference type="OrthoDB" id="3227921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="13017" checksum="FB227212C4FCC433" modified="2023-09-13" version="1">MFSHKPISMFGIAHSFQKDRLRETYIAEYRHIEKDVDAPRQERGRLAMICDHLLDVNIFSSSITTAAGRDRFTPVKADTMDHTVPLLQYPSQSVDSASFKRPVYTSQSSDSFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBS9</accession>
    <name>A0A9P6EBS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBS9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="55" mass="6099" checksum="5FAE199B8E495ED3" modified="2023-09-13" version="1">MVPRQLGAQSLEPGAPVTMLLLKVADPSTHILQLLLFLYFGGFFSIQRIFNGNHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBV5</accession>
    <name>A0A9P6EBV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aspartic peptidase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_795252</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBV5"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040171175" evidence="8">
        <location>
            <begin position="25"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="91"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="122"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="493" mass="53175" checksum="7BD87F239BC30B1F" modified="2023-09-13" version="1">MVHLVYTSISASVLLLSVSVPISAAPQATSQNGQMATLVRRRQGLHTDEEWGKWAKNQRDYLLAKYDQGNPYEKRSSGTNLITNQNADSSYFGSLAIGTPPKPYYVILDTGSADLWVAGDRCDQGCESVERYKSTESSTFKNGTTSFKIQYGSGAAVGSLGTDIVQMAGFAVKNQVFAVCNEVSENLLTNPVSGLMGLAFRAIASSKAMPFWQTLVMSGAWDQPLMAFHLTRFVDAQNIQNEEPGGSFSMGFTNSSLYTGDIDYVDLATPQGSYWLASIHHISVNGNIINFPASRTSYAAIDTGTTLIGGPSAIIDQIFAQIPGSTPGKGDMETYYTYPCNTTVNITMSFGGKQSWSISPSDFQLTRLSKNQCLGAFFKLDSQGSAPSWIVGDTFLKNVYSVFRYSPPSIGFARLSDFALAENGSNSPTPTPTLGPVTTVSASIMPDRGGSKHSSNGSHTIKHHHRELLSQATVIAVPIFVLSAMSFLTNFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECA9</accession>
    <name>A0A9P6ECA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_857881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECA9"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="50"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="37642" checksum="A8A66F13CA97DF0C" modified="2023-09-13" version="1">MVQMSKCPPDIPLKANDANQKSLHKNCDRNSRSSHVLAAATRKVNNSNLIKGSLTLGVGSTGRVYQAVDMSTGLLMAVKQINLELSIKHEFARKTNHAEEQKSRKSRRMSLATAMGLEREITERLVKCVHQNIVRYLRTSWDEKSDFEFLNIFTEYISGCSISTILSKGGALGEPRAKNFTSQILQGLEYLHMRGIIHGNIKGSNILVDASGGVKISSFGILDFKEVDDRSCAIFSMAPEIVKRSAIVTQKADIWSIGWLVIEMLSGKHIWDLIPMQPILQTGSGSTAPTNDDIEISAEAQEFLELVIQIEQEARPRADELQFHFWLVDRSKVEKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECI0</accession>
    <name>A0A9P6ECI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_770041</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECI0"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="314"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="597" mass="68424" checksum="5880DB6EE813C3AC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECW2</accession>
    <name>A0A9P6ECW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECW2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="20732" checksum="FB881A14B66D5B59" modified="2023-09-13" version="1">MASTLGTLSSEYYQYLEIFPGSNSTFPGTYVNYMQAKAKFRPSGLLDSAALVINFRFHRWKWSETPSSMSDKLRHTHSSTELPELAELPSTEPTFSGIFLGSGLLCTNPGLAFLNGVYAVCSNLLPSRHLSPPTRDLVTYCYLILPHINWTDSHSVILELLPSLDDTAPCLASAFFYSAFSRTYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDE2</accession>
    <name>A0A9P6EDE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDE2"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="27042" checksum="9DE4AB8B1CFF406A" modified="2023-09-13" version="1">MPSYLVTGSSRGIGLAIVEYLVTLPDTIVLATARNPGASKGLQDLAAKHGKDRLVLVTLDVSSPASIEAAHKEATALLPKGLDYLVLNAGTHMQPSCTFDDIDFKLLAEEIRFNTEYPIVTIRTFLPLIRKSEIKKIAFISSELGSIEAASQLPGLTNAYCIAKASYNMLARKYGGMLKFEGINVVTIHPGWVKTEIGDGIEAWMNTYAPQMKPITAEVSASGSIKAIQDAKLEEGPGFYNWEGVKRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDV6</accession>
    <name>A0A9P6EDV6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit BET3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_856935</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDV6"/>
    <dbReference type="OrthoDB" id="10262857at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000001">
        <property type="entry name" value="Trafficking protein particle complex subunit BET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23151" checksum="B6F26B28FA9ACA4F" modified="2023-09-13" version="1">MASKQYKSIGEDLWKGRTEKINAELFALTYGALVVQLIQDYEDYDEVNKQLEKMGYNIGTRLIEDFLAKSNFGRCSDFKEVGEAVAKVGFKSFLNITPIVTHGAPPSSPRPQSTGTVQSISQTTSGSFFVLTLDDNPLAEFVELPEEALEGRLWFSNVLCGVIRGALEMVQLQVKAEFISDVLRGDENTEIRVTLVKYLEEEVPVGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEL3</accession>
    <name>A0A9P6EEL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemolysin-III related-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_768804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEL3"/>
    <dbReference type="OrthoDB" id="5585746at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF97">
        <property type="entry name" value="ADIPOR-LIKE RECEPTOR IZH3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="62600" checksum="37A454D60BF243BA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF15</accession>
    <name>A0A9P6EF15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Alternative oxidase</fullName>
            <ecNumber evidence="16">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_815337</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="16">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="16"/>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF15"/>
    <dbReference type="OrthoDB" id="16906at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098803">
        <property type="term" value="C:respiratory chain complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.140:FF:000002">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9527559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="391" mass="44054" checksum="CB8E6D1B7C852C41" modified="2023-09-13" version="1">MIYLPLLRPAAPGVLKRAFAAYTISSKQGAGVVLLSGTAYSGRYISTASPRSNSLTAAKSHQLTVEPHKQDKVVSSSETKSHISKEGAGDVAKQVRGDWVLFHPVYSPSELKAVQVLHRKAENFGDKAAYGLVKLARSIFDFVSGYKHVEGPPDANASLEELRKTGYMLSDKQWLSRILFLESIAGVPGMVAATLRHLQSLRLMVRDSGWIHTLLEEAENERMHLMTFMTLKQPSYFFRALVLGAQGVFYNLFFLCYLISPRICHRFVGYLEEEAVITYTRCIADLEAGRIPEWSTLAAPKIAIEYWRLHDNAKMLDVIYAVRSDETTHRFVNHSLANLNTFTDVNPFALREPDMHLKGGKVELTRDEADKYVTESDELFEKNKKHLKRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFT1</accession>
    <name>A0A9P6EFT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_854644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFT1"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000085">
        <property type="entry name" value="Putative ras-related protein rab-11a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="211" mass="23239" checksum="16FED181EE5F9478" modified="2023-09-13" version="1">MAEGSNYDYLFKVVVIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSINVDGKTVKAQIWDTAGQERYRAITTAYYRGAVGALLVYDIAKHATYVNVTRWLQELRDHADSNIVLMLVGNKSDLKHLRAVPTEEAKLFSTENGLSFIETSALDASNVESAFQTILTNIYRIVSSKTLESNTSNIEPPKTSINVGPSVDSNDQQGNKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG69</accession>
    <name>A0A9P6EG69_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_854194</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG69"/>
    <dbReference type="OrthoDB" id="184182at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9528465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="614" mass="69365" checksum="0D8F125C34F6E6DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGH8</accession>
    <name>A0A9P6EGH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Distal membrane-arm assembly complex protein 1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_854302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGH8"/>
    <dbReference type="OrthoDB" id="6604875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028036">
        <property type="entry name" value="DMAC1-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15055">
        <property type="entry name" value="DMAC1_Dmo2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Distal membrane-arm assembly complex protein 1-like" evidence="3">
        <location>
            <begin position="39"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="96" mass="10094" checksum="69690DABE8B9E64A" modified="2023-09-13" version="1">MATSFETSAASSSFSNPASASETESVKQTGSKANVRDAECLSCRITGTGIMAGTGAYAVWQSRAAAPGTLMQKRIVAGLGIGLMIGSVFRWRSWKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHG7</accession>
    <name>A0A9P6EHG7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease H2 subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribonuclease HI subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_790117</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHG7"/>
    <dbReference type="OrthoDB" id="29098at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09270">
        <property type="entry name" value="RNase_H2-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040456">
        <property type="entry name" value="RNase_H2_suB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019024">
        <property type="entry name" value="RNase_H2_suB_wHTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041195">
        <property type="entry name" value="Rnh202_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13383">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13383:SF11">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09468">
        <property type="entry name" value="RNase_H2-Ydr279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17745">
        <property type="entry name" value="Ydr279_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rnh202 triple barrel" evidence="8">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Ribonuclease H2 subunit B wHTH" evidence="7">
        <location>
            <begin position="96"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="272"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="334" mass="37602" checksum="3B0E81D7CF00F741" modified="2023-09-13" version="1">MSTHFAILPTDHLQLLSSSVNPSSNLDFLRLPHPRTGLPALFLPTQCLPSYSASANTTSILEVQSISPPDERSWILDDNVFADGKMLTMTPVDPAFLLLPILKLAETKVTEANPQFRTSDDIFEATINKLESANSRNEKSDNTLRDDLLRFCSLECTKKALSRLCDSKELSPDIVVYRHSTDRVIKYLRSKVLHLEKAPAFLASKMLTRNLAREGLMEDGQEDMLKLGRTRACCDLLAQYLSSEMRELLLNSYDFSALQKYVELQREEAMRQAAENAPVPRTKSQGTKDKLEEKEASTTAKKRKSNKASHGVETLKKVNTKSMPKLSTFFEKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHP8</accession>
    <name>A0A9P6EHP8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHP8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="43431" checksum="7BA8DDBD54672B38" modified="2023-09-13" version="1">MRALVAVKESFSLMGDKTFNTSMPTVSQAFNELLDLSRWSPEFGDELCFYVNEVFSNPSLPMALPLDIISSGSPKVKFQHAKLLFYLSGITNLNNLAMSLSESVTRSIFDLVLFTCQNLQKIVDPSIRCGSPIAVLWYRASEYTLGSQENSDEESVDDKLTQIVKRVFEFADQTPPDLAVSSNTLGASPYVKTVLQSIANIIVDRLNGPTPISFTLYEKIFLILNSQLKSQHRRGQPNPYLFLLSSIYAHYLLLKVSPHFSRNPFYKRSPPFDDLVDTLTVYHARLTESSELHQFQELIFPQSLKSDFVWAYLGHENSRAGHRHVVAPQLTHTAIKHRYRQGRSQHGAEHKPSKFGQGTNALGGEDKWRVQDSNKYNPIPSPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIL9</accession>
    <name>A0A9P6EIL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_882672</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046616">
        <property type="entry name" value="DUF6729"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20499">
        <property type="entry name" value="DUF6729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6729" evidence="12">
        <location>
            <begin position="273"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="11">
        <location>
            <begin position="648"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="55"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="165"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1376"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1413"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1427"/>
            <end position="1443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9529747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1541" mass="172681" checksum="04292EF1453CB38B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ32</accession>
    <name>A0A9P6EJ32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_851732</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ32"/>
    <dbReference type="OrthoDB" id="6369905at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000021">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000039">
        <property type="entry name" value="Ubiquinol-cytochrome c reductase core subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="11">
        <location>
            <begin position="27"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="12">
        <location>
            <begin position="175"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9529874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="420" mass="43381" checksum="55AD222F56041552" modified="2023-09-13" version="1">MLAARARNIQRLARSFATVVDSTGVKVAAIDNNQPTSSVTVLVKAGSRFEPKDGVANALKNFAFKSTKSRSALGTVRESELYGGVLSTSLGREHLALTAEFLRQDAPFFVDVLTSFITSAKFTRHEFEEYVTPISEGETEAAAHDPATRALELAHSIAFRNGLGRSLFAPAHSHLSATDVQSYAASAFTKSNIAVLGTGIDQATLSSLVEKAFANIATTSSTSPASKYHGGETRVEGHGGPQTIFIGFGTTGAPTAEIATLAAHLSTTPAVKWSKGVSPLASIPEGTSVQSIYLPYSDATLFGLLVQSTSSAGAKEAAKSAVDALKAASKSIKPEALKSAIAKAKFAAANAAESREGLVNTLGSKVFSGSDASLESVLSSLDSVNAAGFSKVTSALVGSKPTYVVVGEASALPYADELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ59</accession>
    <name>A0A9P6EJ59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3 8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_789076</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3 8"/>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ59"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="12"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="171"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="8">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="487" mass="54685" checksum="2EB23FE036E860B6" modified="2023-09-13" version="1">MQQVAQSEQGNPFAVIESDPGVFTSLTRRLGIIGVEVVELYDIAPWAVDHLNPYGLIFCFLWKKDLQRPADFEDPGAEQVWFANQLSDDACATHAILNVVLNCPEIDIGAHLNEFKSFTETMSPVMRGLAVTNSPVIRPAHNYFARPADIRASLNNLTIATFDAEKLKEEQQKATAAASKDTSPPAKRQKLLKVPNQPNGSVKRRGRPRKQKTTPDSGIEDETSGDEDQETYHFIGYVPAHGKVWELDGLKSGPLEVGELPAQDTSVPALKLSKSWMDIVRPALRMKMEKYGGSGMDDSNIRFSLLAIVDDSYLKAHDDFELLRRERQSLENQMNQESPHWQQNVESSLLGIADQLFSRGNHPAFKSSHPGASLTGNDGRLPGFSKSFGSKWMNRQIELMELPSSSRPLRWATCVQNAMRIRTVLEDEINKAAKSNTDHVKRTHDYEPFIQAYIERLHDEGMLNALLDRDNDGRKKRGPKKKVQKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJB1</accession>
    <name>A0A9P6EJB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_773054</name>
        <name evidence="3" type="ORF">CPB83DRAFT_925196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJB1"/>
    <dbReference type="OrthoDB" id="3269297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="306" mass="34180" checksum="E6A625386F9CBFDB" modified="2023-09-13" version="1">MSAFRNYDFTEQVCHPDSPGPSAIAWPSQFPGSLEDESNTHPAPPSPLLKRRDPASNPDLPSPSKRMRLLAAGISTTSASCLVTKGKVTFDQIKQIIAPPVLEHVPKSIPEPDWSLLQDKEPLSSYSRGDLEARCRMLTASLSNAQTVISCHKLITEGQNAQLIIQNIGMEKMSLTLHEKEKPKQTERAALFPDGKGRHLTHPEFIAQKRKAEDDKKREEEEKKQRKEAKASKKALKAKVEERWKAACIEHDQALVHWKTECDRLRAAGTAVKNLPKKPKRVLKKTIEEEMGVDDESDDESVNGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJR8</accession>
    <name>A0A9P6EJR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_834308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJR8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="86"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="447" mass="44279" checksum="8388524A5C009CC3" modified="2023-09-13" version="1">MTLQQRNAARHALIARQGGVGDVPVGGGGGTGNTGGTGTGNGGGNGNTGAGNGGGGSAGGGSSPPPPVSSTPPPASSSAPPPASSNPPASQASSSAPSSTTPSSTQQAATSTTQNVTATSKTSSSSSTRATTSTTATTLSAGSGSRLTTSYARPASITSVNAAGQTIVADAPPDATSASSAGPIAGGVIGGLAGLAILGFLVSFFLRRMNRRNRRRRLALRHESDFGTFNQPEKPSTMAERGHTVAPSISSSMVNNLNGFGAASAGATGAAEVQSPSQNMASNSAASASAAAAAAAQLRERPKYVFGQAPEGSADNATPDDETHGAYSEQPQAQGAYNAEAYANYANYDANNVGVAVSGAGYADAQREYQAQGGYDASAAQGGYYDQSGYYHYAQGQEGYATGYGQGYAQDGQYYEYQAQGGAEHQQQAYAGAHASKPSESAAYGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJS2</accession>
    <name>A0A9P6EJS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_850836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJS2"/>
    <dbReference type="OrthoDB" id="42525at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="235" mass="26050" checksum="E4AAE7447CEEF8B5" modified="2023-09-13" version="1">MTSPALPKLSLHHGSSAIAISQSEIVEDLPTTMKFQPVKIRAAPISDLWRKPPNTDVDNAPTVLISVPLNLHKFHSAKVTVSANWNTQYDQGGLVLFIPDEDTTKWVKTGIEFVSGAPKVSTVAASRWADWSIAPLPEAANGKLTIQVERETKGTERVESLWIYIVNEETGEKEGIREVTWWFRHDLEGGQKAHSHKSLLVGVYGARPSVPEGEGREKEELVVNLDGFEVTMFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJV6</accession>
    <name>A0A9P6EJV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_875102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJV6"/>
    <dbReference type="OrthoDB" id="16729at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28360">
        <property type="entry name" value="DYNACTIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28360:SF1">
        <property type="entry name" value="DYNACTIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="38289" checksum="6C935F768090AC79" modified="2023-09-13" version="1">MNNTSDDNRDRLPLSPSKRAVGSVFLGDIQRHRIFSSSTSNHSGQSTPPSSPPHTAGSSVFSFHHRRNLSSPSPMSKKNDDLDIDLDPAEVAAASVEKIIPEGLGDAIPTNGNPGKVDPVLALELRLRWLEALILGVKQDLGKDRIVFKGKGREADYAAVNATQAIAAANLKPGDTLVRLAQTVQVKLDKALDGNEGLKRFMDSYDQHAHLLTPSFALSGILPDAPAYDKMSLEEINAFLAEMEPDIRAADRDMLEVDALEKKGVLGAGKLPDHQNLDTRLRLLTKSYEEDAALASSLEARISSLVQRHATYVDTLSELFVAWDDTLTDAEEKLSRMERNRAERLRLGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJY9</accession>
    <name>A0A9P6EJY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_851188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat AIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJY9"/>
    <dbReference type="OrthoDB" id="2306at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000102">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000167">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856">
        <property type="entry name" value="WD-REPEATCONTAINING PROTEIN WDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="52"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="183"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="454"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="522"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="608" mass="65284" checksum="4541036C36743869" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKJ0</accession>
    <name>A0A9P6EKJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="2 17">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_834104</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="2 17"/>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKJ0"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 17" id="KW-0288">FMN</keyword>
    <keyword evidence="16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 17" id="KW-0520">NAD</keyword>
    <keyword evidence="9 17" id="KW-0521">NADP</keyword>
    <keyword evidence="10 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="16 17" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 16 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="19">
        <location>
            <begin position="327"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="327"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="64"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="450"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="790"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="506"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="794"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU291113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9530752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1076" mass="115679" checksum="349B46082351D886" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELF6</accession>
    <name>A0A9P6ELF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ARM repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_848039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELF6"/>
    <dbReference type="OrthoDB" id="199930at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024660">
        <property type="entry name" value="UCS_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994:SF1">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11701">
        <property type="entry name" value="UNC45-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UNC-45/Cro1/She4 central" evidence="3">
        <location>
            <begin position="40"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="680" mass="73101" checksum="F236D22D391F1A5F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELV3</accession>
    <name>A0A9P6ELV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELV3"/>
    <dbReference type="OrthoDB" id="2631350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="522" mass="58265" checksum="F3A5190230A63C08" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM67</accession>
    <name>A0A9P6EM67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_103185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM67"/>
    <dbReference type="OrthoDB" id="3070376at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040239912" evidence="2">
        <location>
            <begin position="24"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="539" mass="58074" checksum="0CA78AB973F76583" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMS3</accession>
    <name>A0A9P6EMS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMS3"/>
    <dbReference type="OrthoDB" id="2978551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1141" mass="128102" checksum="0ACE68CDB3623734" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENR3</accession>
    <name>A0A9P6ENR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH-ubiquinone oxidoreductase 12 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_846998</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENR3"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="9206" checksum="2986F8CE962345FB" modified="2023-09-13" version="1">MAVDEAKVAEIQAKLEERENHIRESWVRAMEARIVKDELAKCHKTEGVNHYENCSWLSQKYLNMLKENRVKGYKTIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ74</accession>
    <name>A0A9P6EQ74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_590491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2148418at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1058"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="868"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="882"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="955"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="968"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1127"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1281" mass="138349" checksum="E0653660781AE33B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQY0</accession>
    <name>A0A9P6EQY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_844260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQY0"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000140">
        <property type="entry name" value="Beta-glucan synthesis-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000135">
        <property type="entry name" value="Related to KRE6-glucan synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF15">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="11">
        <location>
            <begin position="264"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="667" mass="73819" checksum="58A66B6633F427AD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER42</accession>
    <name>A0A9P6ER42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER42"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040205501" evidence="1">
        <location>
            <begin position="27"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="10731" checksum="60362799776EFC83" modified="2023-09-13" version="1">MFARSSSIVLFFVLTFLALFTPITLAAPVPVAAPEALASLPVRADAPASLMGRFYQRSHVLVARSAEAAAAPIADSEFEPLLRSERFMLKVKRNQEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERQ6</accession>
    <name>A0A9P6ERQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERQ6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="9517" checksum="846591E73A7A880A" modified="2023-09-13" version="1">MYGKQYDSQGGVMLPGNFGLFTGAVGFPNFRRRNSRNECMYTITKRLSSVHVRRFSHGDTYSQRLSVIAFEKERFLGSLPHPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERU3</accession>
    <name>A0A9P6ERU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERU3"/>
    <dbReference type="OrthoDB" id="3236755at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="298" mass="33359" checksum="6CEE73E14DE77F81" modified="2023-09-13" version="1">MNFLAKYKNKYSEYSTLAILRSYLNPAFLNSDLFNSDPAAASDNDMAGIRHVSTFKQVVIFLLTMAHEEIHHGMQPLLTVWKGKALKFKSTLLSEMKRYARSQYPFNIPMDDGTDIFAWWRSFEGHKEAVVLPSLAIKIYAIRVNSMPGERTASAITWMTPALQSQLSIGQVGAKLLVCQHYMTEKKPRKQAVSRPTVKFYDIKSKMFPKTEVKDSDLKDEADDSWLDVPADPITPSTSLKAEVKSPVNLASSFLATFLAEDNPKRGSAKDVALEGPAEDRAADGDSGNDDDFKMEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESA9</accession>
    <name>A0A9P6ESA9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_235940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESA9"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="225"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="287"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="39093" checksum="0694C9FC41B04D6B" modified="2023-09-13" version="1">MPFPIDHSIIYGFPIIPMHSTRNGDNITVWPVDSYDVPRALHHDEEQQNWLVEQGQACCSRDGRIDGRPLPSSHHQPQHQPQGYSPNFMQSPDLLQSQQPAYHSGYSRNGQPPLSSWNFDLGMATNALMNQTPRYEKAHWNAPMNHPVHPMEPQVFDSPIFSSPNSSSPPALYTPPPQHINGFEFPLRISPSPTPSPILDQEDVKPIISTHMNAHGRRRSSDNNSESGKSCSHCHATTTPLWRRDPSTMKPLCNACGLYLQQRNKLRPQELIDADDDGSTSDESDVNYVGPECSHCRTHRTSVWRRSKTGEQLCNACGVYLRLRGKPRPLSLKKNKIRPRSKHSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETM3</accession>
    <name>A0A9P6ETM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_755601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETM3"/>
    <dbReference type="OrthoDB" id="19394at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="15"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="685"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="823" mass="92453" checksum="8371EFBF52FCB29C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETR0</accession>
    <name>A0A9P6ETR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_339478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETR0"/>
    <dbReference type="OrthoDB" id="3235609at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="58845" checksum="2FDFAFF190323223" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV29</accession>
    <name>A0A9P6EV29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_754429</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV29"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF141">
        <property type="entry name" value="GH15225P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="55"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="31196" checksum="C7DC2C57A0D9A465" modified="2023-09-13" version="1">MPTSDQLQIIHRAKDDAIRRRIRPPLPSQLPVEDELAVKALLQKRGEIVARYGKERVGDGDLDRLRPGMWLNDEIINFYGAMILGRSEARKENPVKSNEKAPLDIFYLSSFFYEKLTKLGYEKARLAKWTKKVDIFSKDALLMPVNHNNSHWTAASINFRKKRIESYDSMYMFNRHVFPVLRRYLEQEHMEKKKKPFDFTGWIDWAPEDTPRQENGFDCGVFTMHFLEAVSRGEDMFAFSQKDMPYLRRRMLAEIGSAQLRGGHYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHX0</accession>
    <name>A0A9P6JHX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_778471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158018">
        <property type="protein sequence ID" value="KAF9521600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHX0"/>
    <dbReference type="OrthoDB" id="3051850at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="24207" checksum="3DF626D5358D0D4D" modified="2023-09-13" version="1" fragment="single">MRSSPHDTAIAHANLLPFPLLVNKVRQAAALRLATLPESHPLHKLVQNAANRYVKSHPTPLHELMYTYKIQPKTMEKLATVRKSTRWKSKLSTKIADTREQAIAEEKIREGKGWRIYTDGSGLGGMIGAAAVVYKGEEVKGSLRCRLGEDNIHTVFEGKGVGMVLGVELARRIEINQTIVVHMGVDNHAAIHATTNNQPTTSHHIWDILHKNVERLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHX8</accession>
    <name>A0A9P6JHX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_878421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157978">
        <property type="protein sequence ID" value="KAF9521866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHX8"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF5">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040461438" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="32"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="331" mass="36113" checksum="F9728074B5B733C4" modified="2023-09-13" version="1">MKWISVALALAVPCVHAALRFGCSSLTLQRLDPLVEPGKAPTSHLHQIVGGNVFNPNMTGDIGAQGTCTTCIFTEDFSNYWTAVMFFKHPNGSYKRVPIMENAALPAGINGGMTIYYTQQDFNSNGNVKMTAFKPGFRMIIGSPTASTKQAVGLKFVCLQDKNTRFPELDNFPTSACRGGIMTVHHFPACWDGKNLDTPDHKSHMYNTVKDAFQNSGPCPSSHPVRVPQVAYETLWDTAQFNGMWPQGGANPFVLSYGDKQGYGTHADYVFGWKGDSLQRAMDSGCMFQGCENGNPLKSQSVQAMNACSVSRMVNENIDGWLPSLPGMGPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JII0</accession>
    <name>A0A9P6JII0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157961">
        <property type="protein sequence ID" value="KAF9522095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JII0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="24088" checksum="FF639834A0FE6449" modified="2023-09-13" version="1">MLRYSKKHVFPTIFNSQASIYVCDSDMLQAEYCYLIILLMVFWYHGFENPHFSLLFILKHSLLNHHRNMEILFLPLLLPIWIHLLALNSAAALRTIIDYTDPLIVYPNSPYEPAILPCHNRTSLYYTASAHISSAKLSLGGLKFWMLVPQGRCGKTEDLFSYTVHIGSEEIYPDESDPHLDDPEMMWFGAYKSEGVQAADFVCAAHLEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ96</accession>
    <name>A0A9P6JJ96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ96"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="80" mass="9020" checksum="60D9DD7BCE8C485B" modified="2023-09-13" version="1">MLSRVATHFLTKKSAFDRKPRRYRSSRVGDKHVQSILRPLKSGGVHPVITLGIFVFTDALRCRGEPHEHFHVSCVGMGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJA9</accession>
    <name>A0A9P6JJA9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">assimilatory sulfite reductase (NADPH)</fullName>
            <ecNumber evidence="5">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_799879</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="5"/>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000003">
        <property type="entry name" value="Sulfite reductase [NADPH] hemoprotein beta-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000004">
        <property type="entry name" value="Sulfite reductase [NADPH] hemoprotein beta-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000016">
        <property type="entry name" value="Sulfite reductase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01540">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011786">
        <property type="entry name" value="CysI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02041">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010029">
        <property type="entry name" value="PRK13504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493:SF47">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="16">
        <location>
            <begin position="684"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9523067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1429" mass="157658" checksum="FE637F35B1855273" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJK1</accession>
    <name>A0A9P6JJK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_68006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJK1"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="64591" checksum="B8C15B9CE27E6379" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJK9</accession>
    <name>A0A9P6JJK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Clathrin-coated vesicle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_863342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEATR5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="192608at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046837">
        <property type="entry name" value="Laa1/Sip1/HEATR5-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057981">
        <property type="entry name" value="TPR_LAA1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20210">
        <property type="entry name" value="Laa1_Sip1_HTR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25808">
        <property type="entry name" value="TPR_LAA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="1003"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="LAA1-like C-terminal TPR repeats" evidence="4">
        <location>
            <begin position="1945"/>
            <end position="2118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="878"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2131" mass="229408" checksum="C44522EFD93D2A00" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJU6</accession>
    <name>A0A9P6JJU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_863136</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJU6"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040031">
        <property type="term" value="P:snRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="7">
        <location>
            <begin position="22"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="29921" checksum="59FD32BC41DBCC43" modified="2023-09-13" version="1">MPNVPTHGNYVGYYTKRPFLNDERLSFLPADLFKGKRVLDVGCNEGFVTCEIAQCHDASYTVGVDIDNSLIQAAWRRRRVVWSLQEPTLPVESNANHDDEPIVRARPSYFPASCEHEFGSLPVPPSQNRGKTNFPHNMGFRHANWVNEHIPEDKDGYDVVLGFSISKWIHLNDGDEGLEAFFRRVFGVLKSGGVFVLEPQPWDSYAKAKKMDQRLKENGNRLKHRPEDFGRILREMGFEDVEHIGDVGVGGFRRPLHLYTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKH8</accession>
    <name>A0A9P6JKH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKH8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="116" mass="12594" checksum="6CB10CD2567022D4" modified="2023-09-13" version="1" fragment="single">MRFVVLRGFYSGIEIAVMLWLSIAAKSVAKSTIDGIAVILNAGFTTDPLAIRRKEVQSVRRRFTLQGSNPIGLLTAGTSVRGSTLKAPRCLWATDKAAWADIPGKKTHHGRRVTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKH9</accession>
    <name>A0A9P6JKH9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKH9"/>
    <dbReference type="OrthoDB" id="2841072at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="64626" checksum="44BE31A9F09FFF02" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKI2</accession>
    <name>A0A9P6JKI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKI2"/>
    <dbReference type="OrthoDB" id="10261384at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019341">
        <property type="entry name" value="Alpha/Gamma-adaptin-bd_p34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659:SF1">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="546" mass="59267" checksum="78D2F1F965744AE3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLP0</accession>
    <name>A0A9P6JLP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_773120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLP0"/>
    <dbReference type="OrthoDB" id="4179406at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="336"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="54822" checksum="1F21D0BB40C793F8" modified="2023-09-13" version="1">MTQQQPRVPRTRSRTRTDEKFENGEDDGERRGGDSDWEDEDDPFWPGHSRAGSPVGSTSAYVRPSPRKRRRPTFPVRGSRKQIPTLASTLTPPKPVRAKEEQDDQPLISQQDVVKGAVDGGAFVAKYSLDIVKRSLQMLKIPFSIVFMLLILGSVLSWARPTIQTALAPICILPGVSRLPICTWGTASSPSRRPQWADYPRLVEAETKTFDQLMDGFVGGGALSLEVKHAEMATQDLVSLIQISDLKAKDTLASLLYEFIYDAKKTGRGLQKLSSKVGGAVDNIMAVNDYALKSIEATRSNEPSRLMQALTPWRPRRKPTDEIVAETFEEATDVLSRNLERLILEAEVSLKNLQDLEERLNSLHELLSREDAFISGAKEDILAELWTKIGGNNKKLRNFDSHLALLKDLAKYRKQALSHVVAALQTLRGMSEDMEDMRERVAAPNLLGPTVPVEVHMKSIEMGLQRLKEGRTRAKKLEEEAMDRVMSLASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLQ0</accession>
    <name>A0A9P6JLQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLQ0"/>
    <dbReference type="OrthoDB" id="3237066at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="66789" checksum="9FAEA67DCCE25588" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM49</accession>
    <name>A0A9P6JM49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Potassium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_943329</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM49"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053952">
        <property type="entry name" value="K_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053951">
        <property type="entry name" value="K_trans_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00794">
        <property type="entry name" value="kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540:SF83">
        <property type="entry name" value="K+ POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="OSMOTIC STRESS POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22776">
        <property type="entry name" value="K_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter integral membrane" evidence="10">
        <location>
            <begin position="28"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter C-terminal" evidence="11">
        <location>
            <begin position="562"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="737" mass="81177" checksum="1AC6325B6954B2CC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMD8</accession>
    <name>A0A9P6JMD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMD8"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF213">
        <property type="entry name" value="DEPENDENT OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="607" mass="65983" checksum="C83F778AE5EE4712" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF6</accession>
    <name>A0A9P6JMF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF6"/>
    <dbReference type="OrthoDB" id="2367685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="571" mass="61895" checksum="6DD4EFF0033FC48B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMW6</accession>
    <name>A0A9P6JMW6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_858590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMW6"/>
    <dbReference type="OrthoDB" id="429520at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.190:FF:000003">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9526054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17320" checksum="211B0D41854BFFE1" modified="2023-09-13" version="1">MEVNFRKINVDQYDEDVIQESELYEADPREPAEVLEEAKQRQVAVRGLLSKNDIAGALTTILDNAPYGPNVESAKEITLQTLLTILNSTKSTEISVIIKSLSMDTQDTLMKYIYKGMGMPGWGDVSGSVLLGWHEKLTEVAGVGCIVRTMTDRRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNA0</accession>
    <name>A0A9P6JNA0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_452686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNA0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12813" checksum="1105178C4C85D208" modified="2023-09-13" version="1">MSETSQRIQNSVVINCCNSLGRQSVLPLELFFYIVQHLEGEYATLFQLSLSCKLLVFYQQHHSRKFHEKDYLRGTYWLDPRPSNAQDFIWLIRSSYTKPQNLDRGVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPD2</accession>
    <name>A0A9P6JPD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-phosphatidylinositol 4-phosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphosphoinositide kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PIP5K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_766872</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14425"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.68"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="2"/>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPD2"/>
    <dbReference type="OrthoDB" id="20783at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000009">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase its3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="13">
        <location>
            <begin position="278"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="552"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="689"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="152"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="689"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="714"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00078403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00080374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00082306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="727" mass="80324" checksum="A561DFC9F79F0A7C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPM9</accession>
    <name>A0A9P6JPM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_869524</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPM9"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="60470" checksum="2FA9E42AB38EDDD9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ98</accession>
    <name>A0A9P6JQ98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ98"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="22111" checksum="DE6036554AE954A9" modified="2023-09-13" version="1">MFDSHPRVSSPSCLRLYLPLGFQSLIGLSRVLSPRFLNSWPVSIFLNCLTEVMSSHPRSRGIIDVSMSRSVEANRERDGKVRKPLLGLEKLNIDKRLCEPRSHERVIGIYGSYWLLSNRVERIPSSSSKNTSRSSCPRKANRVSSSPGSKRPWASFAHEMPREFLFIFCRSLEWNHFDATAYVDIIVVLLSQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQD5</accession>
    <name>A0A9P6JQD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_283059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQD5"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="47645" checksum="42FF571B6F43905E" modified="2023-09-13" version="1">MNQYPALSSIPLELFAAIIDALGDTKTSDNCKSLMACSLVCHYFLPLCQRHIFRTVVVNQNQRSDIFTPTASSLSFAQVISKSPILATYIKKLVYCITASDLNHALADKVAAALQQIDSLQSLVLNCYVLQGPSSDDEELNGRRPIAEFERRLVWDELPLRPSFRRLLQLPTTRGLTVANKIVGFSLQDLGPAVKSLSLGKATSDLSLDGFDYAGPPPAITELLVYDIQTAETLVVGKRSDGHPLLFFTDVKKFAFVWCQSSRSVELCRKLVSKMETLRNFDTLVFSNFSLKGLAEGLAPANIAKTLKHLAVSLYILGSEGETPFKALSEELKEMKGNNVLLTIAITITIPDNCTCATGQVWNRFDEILTSSGSWPCLKKVRIEFRISRKWRQLGDFDRDLANLTSTHMRKLTSSSSVDLKLKCTDRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQM1</accession>
    <name>A0A9P6JQM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_309370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQM1"/>
    <dbReference type="OrthoDB" id="2571149at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="44417" checksum="C81897E0AA78AB71" modified="2023-09-13" version="1">MTGELMPQSVAFRANLAQLVSRLRRVRSRTPFFRLAAHRIPTLWSLYRGLLRASPTEPVKFRVRALFRLNQHLTGIEKTKEKLLLGYKWLEFFQKAQGGNPHCQLVMERYSRLIEEKRAKADLKRILKGELENQLRMRTQPIYTGGFIRPTMFHGPLPRMKPQPEHISMTIRNRIRAREKRITRQAEMQHALRDLELEREFEEGLLREANGNLVSLFSPDQVFNEWTRPIHTAVQDAVEKEIREIKRINTPFSPEMFEKILEARREKVRNKTREKERERRGELTSSAIRRLRRGPPAHVLERMTPKQRAMDKIARSGIEVGYVALVKSRLGMKLKDPDTALEQGQKVNQHLLDEARDVIRKENDRRMREEAKSWVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQQ1</accession>
    <name>A0A9P6JQQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_293147</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQQ1"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="47"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9528979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="160" mass="17103" checksum="0AE3828AD988F9D7" modified="2023-09-13" version="1">MALTEDERKTLIDASFEAKKGAYMPYSKFPVGAALLSTTGEIIKGANIECASYGGTICAERTALVKAVSDGKRSFKGLAVVTNVKKALSPCGLCRQVIREFCALDMPILLVPADYPQPTNPDKEQMPGYTEGGVLATSIGELLPHGFGPEDLELPREPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRU7</accession>
    <name>A0A9P6JRU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRU7"/>
    <dbReference type="OrthoDB" id="3064941at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040511907" evidence="1">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="128" mass="14599" checksum="1884090C3E1340D6" modified="2023-09-13" version="1">MVRVANSILLAAFFCGSAIAHVADLELSGRDLSTYSGEIKARDLMDEDIMNLATRELSTVYARDSTLEERDPFGLGLILKAGFKIAKFAMRHRNHNKRSLDDENDLLERDWSFEEDDLVERNNYDTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS25</accession>
    <name>A0A9P6JS25_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_881782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS25"/>
    <dbReference type="OrthoDB" id="3260094at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="89"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="270"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="539" mass="61337" checksum="11F44A5715B7134E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS46</accession>
    <name>A0A9P6JS46_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium channel YVC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_850884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS46"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="252"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="606"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="800" mass="90084" checksum="87413CC5ABFA00E8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS77</accession>
    <name>A0A9P6JS77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional Coactivator p15-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_760819</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transcriptional coactivator PC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS77"/>
    <dbReference type="OrthoDB" id="2505440at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060261">
        <property type="term" value="P:positive regulation of transcription initiation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="entry name" value="Transcriptional Coactivator Pc4, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003173">
        <property type="entry name" value="PC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045125">
        <property type="entry name" value="Sub1/Tcp4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13215">
        <property type="entry name" value="RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02229">
        <property type="entry name" value="PC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54447">
        <property type="entry name" value="ssDNA-binding transcriptional regulator domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcriptional coactivator p15 (PC4) C-terminal" evidence="8">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="12132" checksum="2599DA13E4357E1C" modified="2023-09-13" version="1">MTQKKEKPKTIKKPKIDTKPSASVRKSTDSGKVKTNAEGDQYIDLGKKKRAVLRSFKGIPLLDIREYYGAEGEEKPGKKGISLQLEQWHELRDSASTIDQLFTQLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSJ1</accession>
    <name>A0A9P6JSJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSJ1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="102"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="739" mass="83639" checksum="916439365EA317F4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSQ4</accession>
    <name>A0A9P6JSQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_881231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSQ4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="27415" checksum="C0357EDA5456A18A" modified="2023-09-13" version="1">MAKLPIDELLRFHKAAEEEIQKLKKEYQSLHTSVLHNPGNAEEEIEKLKEQSRSLHTSILHHLEEFEAAQNNDIHEVPQENQDDPERTGIQEHGPTRQQEQEDRKRKEAEQEARRVRLLMKQLSLLSMTKMAGMVLAALLLALFLELLGWFIMTGLFVTFYKDPHCASEHCLGYFFPGFTTLEYCGCKSSSLQNPTTIEAKTHSVFLDLQSINGRIFGGKNQNPTIVATGTLVQMGDRKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSU9</accession>
    <name>A0A9P6JSU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_144149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSU9"/>
    <dbReference type="OrthoDB" id="3066809at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="389" mass="42683" checksum="FBC178BFF5CD3574" modified="2023-09-13" version="1">MSSSASRMSAQGPTLPPIRSLQQPAGATDAHRLPTTNRLPPLRRPVQPNHRSTNSLGASIPTSGLAHTPEFFNPIHRDIASSMAAQEGLSRSLEKAFNVYNDRVRSDLRDFRGLCTSLVAQEQQEAMKWYSLCLKVMKERDIARQQLHLLSLERNSGSLTSPPISPSSTDQEAELNKALKRGREDYMMSNTVETASASSRSSSVETRPTRPLRLSPVHSPSGSPTRMSTSPLPVNDPSPSTLSASPTSMALPPSPQTNSHGRVDHRPGKRRKSCEAIGPTEVSSPRVKQQSRTPSPLSFPGHLRSLPPQQSADFPHIDLMYVPTNGLLVCRACILHKSKAPTVEPKSFPTTASWDDLRQHCLRAHPEACADVARLCPAEIFELRRRLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT43</accession>
    <name>A0A9P6JT43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_808097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT43"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="467" mass="53459" checksum="B49C87A6BABEEE61" modified="2023-09-13" version="1">MHQLSCKAPWLFNGDGALMNITSRTCLLFLVITTLAWFSNHQNLNTTVVILNWSRLPNVNEIISQICTNLLDDTVHEIIIWNNNPQELSFYLSFPNTTCPQDKLRIINSPANLYFQARFMACAEVKTKYCFIQDDDYLIRPRIIRALSQRMESRRLSSIHLQPPHEMLTSELRTITIQDNIHATFAWLGYGTIIKRSLAVDFLALLDQLNLTDEEHKMADNYFTILGNWLPERWFDPGISLGGGQPFTVGSEGEERNNRHIRRAADLLNEIMSTNRTWPYVSNFQSNRYTKAITTAPCQQSACIFETSINLLPSNILEVYSAKSAVDILIVEQQRKSAVGENRVSHYLDFPPSNAVDGETNTAFCSFEGVGENDWVSLQLLDSRRTIDLGLVVDQASATLIEEANTETSEDGINWILSDSTWTCEAFTKDETGRLICKEQLDLTTHYIRLRMSRDYRQRLCIFEIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTI6</accession>
    <name>A0A9P6JTI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IgA peptidase M64-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_783714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTI6"/>
    <dbReference type="OrthoDB" id="2961863at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019026">
        <property type="entry name" value="Peptidase_M64_IgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09471">
        <property type="entry name" value="Peptidase_M64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040105807" evidence="2">
        <location>
            <begin position="20"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="61141" checksum="2502B43B16A65719" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTP9</accession>
    <name>A0A9P6JTP9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase RIO2</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Serine/threonine-protein kinase rio2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_760537</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTP9"/>
    <dbReference type="OrthoDB" id="10258631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000053">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000052">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="15">
        <location>
            <begin position="65"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00068353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00068837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9531994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="339" mass="39031" checksum="3DBCF070DF147B4F" modified="2023-09-13" version="1">MKLDATDLRYVTSDEFRVLTAVEMGSKNHEIVPLPLIVQISGLRNGGVNKLVGSLAKRNLISKVQNAKYEGYRLTYGGYDYLAMRTMSKRDTMHSVGNQIGVGKESDIYIVADAEGSEMVLKLHRLGRVSFRAIKEKRDYLGKRKSASWMYMSRLAAQKEWAFMKILHEHDFPVPRPIDQVRHCLLMEFIDAYPLRQVSDVPNPGKLYSDLMDIIVRFAHAGLIHGDYNEFNILIRRETGEPIIIDFPQMVSTSHENAECGFPNLVFRYFNRDVECIRTFFKRRFRYESALYPKFRKIVNASGEEGFKLDVMVEASGFGRKEMKVLEEVRSFHGSENCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTQ2</accession>
    <name>A0A9P6JTQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_87321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTQ2"/>
    <dbReference type="OrthoDB" id="3130513at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="235"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="469" mass="51578" checksum="D523E55B962321A6" modified="2023-09-13" version="1">MSGNTAPTLETKVFRLEHSGKALEAKDSLSFSVPSNSPNQLWSSYSGVNGQWIINRGTGAYLVVDNNTVGVKIELPYEWNIQNDGSSVRLEAASQKIYLQSSQQKLAVSPKQDADSLFTITYVTKPVLTVGSKDYVESPEHTCVANHVFNTVNALNAVIHILEHPDSTLPVDSMAVLFRDHIKLFTARGGEAAENLELARQTVASWFAVIGAKMNAEVKDKGTTESSTRNENPGLKAAEKQLAELGTTHTKTKAELKEQEKKIKTAEDNYESEKKHYENAKANEDLAKGSYDDALAEPVLELDEADTSTFVGNVWLAKKAEREGAEEKKNSRKGELDREQGLLKTLKDQSAREVIDIAKLEADVKKAKSVTDDGASKKRDYQNHHQTLTTLYGLLKDCREHLIDTLRYNVGGGAKFSAVREKLKGLVNALEKGEDFKEPLKILDRAALDHLMTRIPAITGGSPAGKLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUB0</accession>
    <name>A0A9P6JUB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUB0"/>
    <dbReference type="OrthoDB" id="60858at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="20440" checksum="739A0ACC741C0EE8" modified="2023-09-13" version="1">MAPAKYHWISAWFAITAPIILWDAGYLLMRPRSMEGGDLRWIWSFFDIYERIDNVYSIKGYYEKAGFGPAAAVLNIIETTLNLLYLYFVHVAPNDMAPIFGFSGAGLTLAKTTLWALQEHFCQHCSYAAGMTNFTEFFKFWIAPTVVWYIFCSSIVVTLGTDMASALSGRTESMLQHKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUX9</accession>
    <name>A0A9P6JUX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Galectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_758032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUX9"/>
    <dbReference type="OrthoDB" id="3018764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001079">
        <property type="entry name" value="Galectin_CRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00337">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51304">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Galectin" evidence="2">
        <location>
            <begin position="15"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU102079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="170" mass="18869" checksum="91C159F733B6B26F" modified="2023-09-13" version="1">MATPSRYFHKVPLNQITTLPEPVKVDGILIFRSFDLNMYASLSGKGDYTLLDLLNAGGDVMLHISVRCCQNAIVFNTSTKNTGWGPEEIVELKGHFEGFNTTVAIYNHPDMFQIITNGRTAHYFKKRIQGDVAKLSYFTAEGLPSFFSDPIAVETFKDWGALVPGSRSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV56</accession>
    <name>A0A9P6JV56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV56"/>
    <dbReference type="OrthoDB" id="3364747at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21177" checksum="9A24AD280B473F79" modified="2023-09-13" version="1">MPLWISTKKEEPQPVQAQPTSPELLKKVETSIIKEAKDEEKNLKHVVKDLAATQKALDKARKAADKADSNMKKAERNEHQTQKNLHRAEHNHERAIADVKTAQKDQELRKKELEKATQALELMKSRVDTTIKEHDEHTEERNSKLAHLRSERVSTSESTGPVVEVAPVPAQAQVPTQGTPTGSLEPSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVH3</accession>
    <name>A0A9P6JVH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CPSF A subunit region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_756026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVH3"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="12"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="511"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="914"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="417"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1278" mass="140627" checksum="2620341D0CE5E150" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVR2</accession>
    <name>A0A9P6JVR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_843771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVR2"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098717">
        <property type="term" value="P:pantothenate import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000386">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="35"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="457"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="500" mass="56077" checksum="766C579E1FFE23ED" modified="2023-09-13" version="1">MGLLQNAKNGLRIAGGRRPSSREEKRLLAKIDWFILSYCCLMYFSNYLDRSNISNAYVSGMREELHMVGTEFNKINTIFTCGYIIGMIPNNLLLQVVSPRIWFPCMQIVWAVLTFCTSTVGNVKQIYAIRFFQGMAESSTFVGTHYVLGSWYKPTELGWRSGIFTSSGLVGTLFSGILQAAVYRSLNGRAGRSGWRWLFVIDGIITLPIALYGFLVFPDVPKTTKAFYLSPEERELARTRLDQNTNLEQAKSRPLSWALVRKILSSWRWYACSLLFAISGETESFGSNNLMGQFLKGIGGYTVDQIDNYPSGVMAVAIVSTIVCATWTDRTGVRWPVLIYMSVACIISSICILVWSSPTALKFFAYYLAGASYAGQATTFAWANQICADNDQERAVVLASMNMWNNAVNAWWSIVFYPATDAPRFRKGMIAMIAVCIATLLATWLVYFLERREWRNRDPRSGRESVDKEGLPGSSGDVQKNQNSPTVVDSDTRSVASEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWK4</accession>
    <name>A0A9P6JWK4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BAR-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_754324</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWK4"/>
    <dbReference type="OrthoDB" id="2159336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="15"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="400"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="306"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="50840" checksum="4C9E0444AAC9D538" modified="2023-09-13" version="1">MKGIGKALSRTPFAVTTKIGMAKRSADTEFDEYARHFGNLESAADKLIKDTKAFCDAVTALFTSGDGYATHYSVIMTPIAGEYDLIGKHPDSGHTIRSQDHYAQAMKELKELIGPELELIESRIMGPAKEIQVVMKTIRKTITKREHKLTDYDRYNNSLTKLRDKKDKSLSDEKNLFKASPAILCLELEQDFEVATNEYDYINTALKQDLPRFMMLATQFIDPLFSSFFYMQLNVYYLLLEKMNSFADENKWDVANTSGAQIAGEYEEKRTDAWQRIEDLGVVKRIVSVSRLVQASRAQNGGAPGSLGRSNTTASSSSSLKPAAPPSRSTSSASGYKKAPPPPPSLGGSRGLSPRAEPAPPPPYTASSSVGSTTLAAAAAKRAPPPPPPLKPKPGLKPKPQIQYVVALYDFAAQADGDLSFNTGDRIELIQKSESAEDWWTGRLNGVQGVFPGKFLYKNSFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWL1</accession>
    <name>A0A9P6JWL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="10">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_872580</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="10"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWL1"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.320:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000007">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006765">
        <property type="entry name" value="PRK09287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="5 10" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="229"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9535816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="539" mass="59102" checksum="4EF70377259C882A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWW4</accession>
    <name>A0A9P6JWW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_779631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWW4"/>
    <dbReference type="OrthoDB" id="2140240at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040144453" evidence="2">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="30367" checksum="62FB7203D621C31E" modified="2023-09-13" version="1">MKFFSSVFVLSATAVSVFSAPGVPNVRRDVDPGLIPEFGHAAGLNPTGTGDCDGVTNAAGVVVKVPCFCPPDRAQFIQQLNANVKAGRAVNNPSVAVTFQTGDDKASKLTRIGAALVTLQNMRGPGVGCPAASTTFVAQQKAIQDGTDGAAPAPAAPAPAPPAAPAPAAPVPAPPAAPAPAAPSTGDFDESLVPQFGLQSGLNPTGTGDCDGIKNAAGVTVKVPCACPPDRASFIQSLRANAAVGHAVNNPTVQLSFPNGDDKQSKLARIGAALVTLQNLHGAGVGCPAASTTFSAQQKAIQDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E391</accession>
    <name>A0A9P6E391_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157999">
        <property type="protein sequence ID" value="KAF9521708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E391"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="12818" checksum="58A5207E7C440A8F" modified="2023-09-13" version="1">MKSTLEKILELVRKIDVRSRKDAEKNSQFQGVMRDYIQDGIDKEAEDIEFKNNMSRWTMAIMAHLGVEFDREKIIEKVTSKGGEAGSSKGPETMDGEKKGEDGEEGSKGMDTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3T2</accession>
    <name>A0A9P6E3T2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_737186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157965">
        <property type="protein sequence ID" value="KAF9522023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3T2"/>
    <dbReference type="OrthoDB" id="3067373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13326" checksum="FBC2C37DB3FC9924" modified="2023-09-13" version="1" fragment="single">WTASKSNEYPSIDFGNRYFTPVTDAPMHTVIPFPCDVDPAGALGAAGKGKFVHTIDNQVKYYERVGAPGPLRYTKAVPSIVRVGDIVEAQVSFVVVNLSRGRFKMFPTLRSVALLNDTPLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4L6</accession>
    <name>A0A9P6E4L6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD40 repeat-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_864612</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4L6"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="282"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="325"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="9">
        <location>
            <begin position="358"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="415"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9522324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="449" mass="50602" checksum="37163B4A054C3727" modified="2023-09-13" version="1">MVKISVLQHDPSVHLPVRPGDPTPVSRNLNPLMHPFAKARERTRALNAAKMDRMFAKPFVDALEGHVDAVEVLCRRPGSLTNIASGSWDGGVIMHNLSTRSQIFNISQAHKGKVSGLCFSNGEGERLLSCGVDRNINLWAINEETSTTQKPLTVFPGKTAFNSMDHHRTDPLFATASNTVQIWDETKSAPISNLSFPTSTETITSVRFNMSESSILASLGTDRTFTLYDIRTGKAERRVVMQMQSNALAWSPTFPTTILLASEDHNLYTFDIRHLATPTQIYKAHVAAVMSCDWSPTGTEFVSGGWDRTVRIWQEGKGHAPEVYHTKRMQRVSSSIYSADARFVMTGSDDGNVRIWKAKASEKLGVVTARERASIEYRDSLKERWKVDKEVDRVARTRHLPKSVHQTAKLKREMLDARRVKEERRRKHTRVGEEKPKPERKKTVLVEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4V7</accession>
    <name>A0A9P6E4V7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_871954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4V7"/>
    <dbReference type="OrthoDB" id="3363891at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="756" mass="81902" checksum="E3F8E81FACA98C0A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E541</accession>
    <name>A0A9P6E541_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_871922</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E541"/>
    <dbReference type="OrthoDB" id="16079at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034246">
        <property type="term" value="F:mitochondrial transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006391">
        <property type="term" value="P:transcription initiation at mitochondrial promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF17">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="43142" checksum="E461378A2B2A5B9A" modified="2023-09-13" version="1">MKGLRNSKRGPKIVPTPEVTGWELPDIEKWRLYFPIEKVASRRANIRNPDTAQMLAEAFVPSGSRDKIIIDVLPGPGQLTRALLKLPKCRIKKIIVLEPANTFMPYLKSLETLDPRVTVYQYHGKEWDTYRKLKELGAFDDIVTTDWNDGSSIVHPQLQFLMHMHSSIEGEQLLSQLLRCVPERQWFFQYGRVPLNIILPAPVWERVLAKESTPIRCKLGVIAQATMEIQNAVDPRKLQPFEHHFHPKPMLNFADAALKKGAIPHVALTMTPWKDSPIEQGDMDIWDYVIRRLFVQKATPVKKCLESNSLGPGAANMIPKLTDSSLPEDSILDLTKIPRNLAVHDWKLIVDAFKKWPFRPSELGINTFTERPNNLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E549</accession>
    <name>A0A9P6E549_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 15 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_89664</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E549"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000051">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Ktr4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR018153-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="385" mass="45406" checksum="4F5F1EA93C3D30D9" modified="2023-09-13" version="1">MPGSMEGHVIHNYTMMMGNKKNTKFLYLTLAIIISLLFVFEAWQPSDIDSTPPVTTSYWKHNHPPPLGRRANATILILARNSELAGVISSVKQLEDRWNKNFHYPYVFLNDEPFDANFKRRVKELTDSQVEFGLIPLPDWVQPDWIDESIASKNREHLVKQGVIYGGSVSYRNMCRFNSGFFYRHELLTKYQFYWRVEPDVTYYCDIDYDPFLVMQDQDKLYGFTIALTEWKKTIPTLWKSVKEFTREYPQYVSPHNAVDFISDDGGYSYNTCHFWSNFEIANMDLWRGEAYTKFFDFLDKKGGFYYERWGDAPVHSIAVSLFARRDQIHYFSDIGYKHEYFSNCPQGEQHRRGKCWCDSKSSYQLKNGALQITSCLARYEDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5M1</accession>
    <name>A0A9P6E5M1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine protease inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5M1"/>
    <dbReference type="OrthoDB" id="3439489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16391" checksum="E94973AA58434D31" modified="2023-09-13" version="1">MAPLPNGRYIIRSVGARKFVGRSPREDYSLLPKRVILLPDGVQAPFFEFQSTDRGTKILAGGNSTAEIDRNLFAVLLPEPPAEDWKIQAIPQSGKNRYIITKSNGYEGWIVGDDSPEAQIAIRPLIIGPSEPPFYPPNEVWEIVPYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5N3</accession>
    <name>A0A9P6E5N3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5N3"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="57199" checksum="C592213E0979A3D8" modified="2023-09-13" version="1">MDQPCNACKAHSEVKTRILVAEAQLAALKEEERSLRSRMNEAHDPMHTLPSEIASHIFEGIRTTTWYPSIQPFLALGSICQYWKNIAWATPSLWNELDFLLNPSEHPPNHSFQSRTELFQECINRSGVLPLRIYIYSSEETYSYPPWSQIRPLVDIITQPHLINRLTDSVLRLPTSCFLQLEGLVAPMLQKLILQTPFSNERIGFEMDLRSFTNDLEELAVIAMDLDRINISCKKLIHLEIEQCSPSSCIGTLRRAEALQSCTLKMLNTRLPDIGDVDIPTVQTQLTNMTIFYDGPSGTGSFLDLFSFPSLDSLRFVSSQLINFPQVSSFLSRSHCPLTKLYLPSCPRGRSYWPLADLDTLLVLVPTLSTLHVSDIIDSPSVADTFRTVFASGSTTPAVTNPSDSQRAVITDFRYAATWNAVDSFNRWAFISEVFSSTPTQLPKTIRLSLEIPAEEKDGIWVPAEAIEIVRELQLQGWEFVLQGHYRGRLIKSLVEVSVAHHQDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6E6</accession>
    <name>A0A9P6E6E6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_775620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6E6"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF141">
        <property type="entry name" value="GH15225P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="35"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="29370" checksum="55523C014110121B" modified="2023-09-13" version="1">MGANGIPAELPEAELEQVKLTFKVKGRRVALIKTTPIEDDDFRRLRPGRWLNDELINAYMILIQARADRPARSTDIGFRTAPLRLIEINRNIFCFGTFFFHRLVRHGYQEAKLSSWTKNVNIFSLDRILLPINHFNNHWTAASINFTRKRIESFDSLEDSNHGRVFKFLCQYLDAEHRDKRFEPFNFSGWINYTHPMQPLQSNGCDCGVFTLVTLDALARGEDDLLFDQSNMAYFRMRIGWEILNGTLKTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E827</accession>
    <name>A0A9P6E827_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E827"/>
    <dbReference type="OrthoDB" id="3269515at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="26881" checksum="F3634506E8C82875" modified="2023-09-13" version="1">MTDLTVLVSPLPLYPNTGDFTFGRKTKHKPIMVTLETEVDEDLKRADMEADNSEKPRTSDPDFIRPPPVFPTPKRGRSPRPVDHSLLSPPPNTWKSRPRHRPTRSQSAPPERTLAIGTNVSPEGGQYSTLQSPVSAVELPSTNILLGLGAPLQRTAARSFSSQASTKKTGELVRPPPPLLRPTTFWRKTRRSGVTGASYSPSSHLIRRSTYIAAGLAFDSPVHDLSALCVESRVGFIVVPPEDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8E1</accession>
    <name>A0A9P6E8E1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_909970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8E1"/>
    <dbReference type="OrthoDB" id="5402897at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="17359" checksum="80BD2257152E0E9F" modified="2023-09-13" version="1">MSVLSYLGNVNIGIHLVEKLNPQAVLYEVDGSTSDGKPTNDTANINKLRFGNNTIILNSGPLWGEWAAPIYVDQPTMDDIVIPWPIDMDIKEAQKLKDEAGYKTDFTTVTLRWPLYPGNSEPYYIFGLKGYYVFVGVYSGKVFTEDMNKKKKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8P3</accession>
    <name>A0A9P6E8P3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_605146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8P3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="382" mass="41917" checksum="5E62B135710A638B" modified="2023-09-13" version="1">MNYYPGMSSNFDYTPSENYQQEFKFPVDSTQFYAPVAQPIWSPQNESDEYSLSSSSSSSYPSTPSTPSLGLYDDDFNLWGNPQEEMFLPTPSTSTTNAYLSPPTIYGVDIGAPYDPRFASYPSNGLTSLPTCYEPPTKNPQPLMFAFGQQVAGNTSVTSAPLVSTGYTPPFPMPSATVPPVGTAYRHSVGVSANGVYHRTPMSMAPIPLMSSMGPTRTMAASKARRSISRNKNYPMPPTNKKSSPPLAKPSTTVKTPRSKRLRTTTEAPLNVTFIKGDYLCNWQGCTARYDNPIEAEDHLTKSHKLAKNHGGKGDSYVQCELKTEHTCDGSTGGKKGWYKKGSLVRHVIAKVCVNKAQCNLCGKKYSWRKDTWGNHPCLPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9T8</accession>
    <name>A0A9P6E9T8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9T8"/>
    <dbReference type="OrthoDB" id="3038602at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="62" mass="6800" checksum="38F3B51200B5D76A" modified="2023-09-13" version="1">MLQEGFAEGVPSKTIKLRVVDKTKGGSSYETILEDGVIYVQTLPDRWWCNVSEAGSNIVGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9W3</accession>
    <name>A0A9P6E9W3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_796405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9W3"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040318585" evidence="1">
        <location>
            <begin position="22"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="34"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="557" mass="60048" checksum="2FC35D0F0EA25A3D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA21</accession>
    <name>A0A9P6EA21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_546657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA21"/>
    <dbReference type="OrthoDB" id="9978173at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025533">
        <property type="entry name" value="DUF4419"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252:SF11">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14388">
        <property type="entry name" value="DUF4419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="388" mass="43561" checksum="53DECD3375B32323" modified="2023-09-13" version="1">MPVTFELAQHPAEPVKATEDGPISSPEDLLARTWGKNSETHDYDELLQTSLSAEIPVGGEWSQFRPQQNGFVHTIVDAYNHHHHLVLRPDDVWVAILSQFNLFVNAHAAELRSIFVQHNSQKHLILRADGDRRTVNFGDLAQQLTRNIEKKILDKTLRDWILPDFSTTRANDTAICAILMMSALKSYFTYEIRLRCGIPSITLNGSKEDWSSVVLRLDKLASFGQEPAAFAELLRPVLLRFVQAFDKNELGEVQDIDFWSKICHVATGGSGPPHLSGWLTAFCVWNQDGQWMGPKLPRQPANTLKRVPRSGHAAVAAAAQIPLILDGVEYKKINFDNVPRGFCEVDIKLNDNGEIFATKMVSGHVGSVIEGEKRDTLKPLLAWFMFTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAN2</accession>
    <name>A0A9P6EAN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_896616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAN2"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="31130" checksum="A57D966786739BC5" modified="2023-09-13" version="1">MTGTMTNFFNAMLPQNHNGHNHNNRLAVPTQGVKVNKAPSISSQYLATTSLHGQVAVVTGSSRSTGAAIARCLGEHGANVVVNFVTDSLAADEVVQSIRSQGKGGAIAVKADASTVEGGRYLLDEALKTFGKVDILVLNSGIMGSKTLGDVDEAFFDTQFAINVKAPLFLAKAVAPLLPSHGGRIIFFSSTLTTSSAVSPNALCYLATKGAIEQISRVLAKDLGTRGITVNTVSPGPIDTPQFREGKPQNIIDSIARQSPSKRLGEPEDVAPLVAFLASPAAQWINGQIIRLDGGAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAP5</accession>
    <name>A0A9P6EAP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_859492</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAP5"/>
    <dbReference type="OrthoDB" id="1405469at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000306">
        <property type="entry name" value="IKS protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF138">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE IKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="835"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="232"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="170"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="346"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="673"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="684"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9525399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="890" mass="97447" checksum="417CDDF3E7DC63C9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAW0</accession>
    <name>A0A9P6EAW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Angiogenic factor with G patch and FHA domains 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_795995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAW0"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053027">
        <property type="entry name" value="AGGF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106:SF24">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="101"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="3">
        <location>
            <begin position="328"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="42804" checksum="12F458773DB80B2A" modified="2023-09-13" version="1">MESALEEGQLADVWPPENRSEATELQVYNPAYEWPGESVDAHAGPAESESQGHSAGEPSSSLKPGQPIFRLVAEYSSVIFSKQDKKNEKKKVAMIDSYHEVQLGRDLQAAGSITPRIRLKEMEVSKLHATVFWDGARKEWNVVDMGSKHGTFLQGHTPNLLGVTLTEKDVGVRLSQPRAASVPWRLRHADRLRIGSTTFAVHIHDNQRPCQECMVSGKEELPLFPTTEQVTQKRTREVAELDSDQHLAEPLETRNPKKALSMLKRNLLSRHTVGSGSSSSKEYTDRAARRRMMCPTSRSDSPGVASLARPTPIVSVEPVSQAPAPLPVSNIGHRLLMKQGWSPGTALGLDDDNLVEPLEVKTTQNRAGLGMKLDWKGHEKLTHFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB36</accession>
    <name>A0A9P6EB36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB36"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="18037" checksum="D3C32E10A667317B" modified="2023-09-13" version="1" fragment="single">MKLSPRPALLFPKLYLCPLLLSQQTRRSRLHGSNSIVDICSAIGFNEPHLAFHRNHPIRTDTRICEEHASLSQLEKLEIKFLHDPYVNPSHQPTSLTAVLKEDTSKALRRLLEIHSETLEELDFIVPRSSEGDITADNSFKLIHTPLPQLIKMSIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBG4</accession>
    <name>A0A9P6EBG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_817814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBG4"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604:SF3">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="758" mass="85624" checksum="81271B7CC94C0578" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBG5</accession>
    <name>A0A9P6EBG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_908784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBG5"/>
    <dbReference type="OrthoDB" id="3193353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="520" mass="58713" checksum="40F4E0C5E545BE41" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBT9</accession>
    <name>A0A9P6EBT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_858679</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBT9"/>
    <dbReference type="OrthoDB" id="308449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="109"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="193"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="345" mass="37907" checksum="B6EF803B5723B4F6" modified="2023-09-13" version="1">MSSRPQKKVKVAVQGSKNDTQNVALKSSIPNTQKSIVTAKGKERETPADSDAPLRSPTKGKEREDNTRPPTSFKVVAGSYEKLLYGLDGIITIGENSKLSFELKPMFIFPAHVSCIKAVAASPQGGKWLATGSADEIIKVWDLRRRKEIGGLMHHEGSITHLVFPSRSHLLSASEDGSLCLFRARDWAVLRSLKGHKGHVNAVAVHPSGKVALSVGKDRALRMWDLMRGKGVASTKLDKEGEIVRWSSDGSKFGVQSGSNIQIYATNMDLLWTISHSSRIHDIKFVKLHDDDAEVLLVGAEDKMISVYRVPTESSKSPTILSRMVGHVNRYTTSSKSYLLSTYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBW0</accession>
    <name>A0A9P6EBW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBW0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="51" mass="5501" checksum="9EE0551DC3110867" modified="2023-09-13" version="1" fragment="single">MISRGFEYVGQIRIAFSSLLLAALTIATVVVLSVTSISFFTATLVICSLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC39</accession>
    <name>A0A9P6EC39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC39"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="659" mass="72593" checksum="F57FA51A16AEA02E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC67</accession>
    <name>A0A9P6EC67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC67"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="16919" checksum="4782DF68721D9B44" modified="2023-09-13" version="1">MSAPTSTSTTSTDVVGASRELQDALYGFLGLDFKMIQNGAIPLEDRAAITKMTTDKVINAFNKLDPILKGANSNKDGAIKEIQDAHAVLKETKAQFTELDRTLKATTQDDGDSFDLDELFTAIERVFKHPVVQKAPEALWKVARNFFPVIGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECE7</accession>
    <name>A0A9P6ECE7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECE7"/>
    <dbReference type="OrthoDB" id="3034033at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="39607" checksum="61C9C70D818F35F8" modified="2023-09-13" version="1">MAFTTHSRTENMGDVLRRANLHCSALAKAVRAALRPTHHAKKHALALQLSVSTQAAAKLDQRQISVLPLPILDLAPSPLPAFTSHPTEASSDTIRIFAPTPIYLSEIQVNELNQEICRPARPSLRCVIPSPKQASLPISLEIVHSPALECLSCDFGDNMKSRWSASTVGETGNSSAFVENDAAEGGMSAFEEHQDGNPPCSSPSFIEREEDEAIASLRPRVAVSGFARSRISIPAHLTQPRHSVGLVITQQKLSNSPPRLDVPVDLSRMSWGSDLFLGPHSGSSRSSSCGPVTPRTPDHAHQSTAPSSSKRKANPFESADDDSVATALIFEKRPRFERKPWVMTTTHRREHTRGTSISSRRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED27</accession>
    <name>A0A9P6ED27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_768845</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED27"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10 12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="530" mass="59269" checksum="972F9458FA4A6882" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDC2</accession>
    <name>A0A9P6EDC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="4">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_876490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDC2"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CBM1" evidence="6">
        <location>
            <begin position="290"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="256"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="328" mass="34528" checksum="1B39D54CBF04AB7B" modified="2023-09-13" version="1">MFVYRPSGLVANPALIVAMHYCTGTAQAYFSGTNYANLADQLKTFMLIYPDAPDSGGCWDVHSTGTLTHNGGGDSIAIVAQVKYAIANYGVDSSRVFMTGTSSGAMMTNVLAGAYPDVFKAGAAFAGVPYACFAGAGMWNNECANGQTTKTAQQWGDLVRTGYPGYTGPYPKLQIWQGTADTTLNYHNFGEGVKQWTNVFGYATTGATVQTNSPLNGWTRTIYGPNFQAISAQGVDHNIPVQANDVLNWFGITGNQGTTPPPVTTPPPVTTPPPVTTPPPVTTTTTAPAAGQTQWGQCGGQGWTGPTTCVAPFVCKVSNQWFSQCLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDG4</accession>
    <name>A0A9P6EDG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_748494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDG4"/>
    <dbReference type="OrthoDB" id="5273213at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="5">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="534" mass="60133" checksum="377F21AC574C0863" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF34</accession>
    <name>A0A9P6EF34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_869535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF34"/>
    <dbReference type="OrthoDB" id="510325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="4">
        <location>
            <begin position="18"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="100" mass="11594" checksum="639DF0A028B24F6E" modified="2023-09-13" version="1">MSEAVEKIKLVHSPDLATATFQIHDESHTIGNPLRWMLMKNVPHPSENVINIRIQMYDNLSSLDALISALSELDKVCEAVEDQYLESLREGKFERWDERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFU0</accession>
    <name>A0A9P6EFU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_894608</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFU0"/>
    <dbReference type="OrthoDB" id="5420143at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052479">
        <property type="entry name" value="GPI-anchor_Adhesion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185">
        <property type="entry name" value="SERINE/THREONINE-RICH PROTEIN ADG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185:SF1">
        <property type="entry name" value="UPF0619 GPI-ANCHORED MEMBRANE PROTEIN C1322.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040431496" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="19883" checksum="72F9F59E694176E3" modified="2023-09-13" version="1">MFGKISLIAVVLPLAACLQIAVPEHPTSQGTITIQWTSANGDPDTWSFELVNVDFHDTFAIANNVDPAAQELTLTLPAVPARDAYTIQAVNIGNITDVYATSGSFSIGAVSSSSASGSSTSSSGTGSSTSSASTNTGSTTRTSTSGSSTGTNTGSSQPSSAAPSTFNSPSAASATLPFGVTSGGLLAFTASILAGAAMVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFY6</accession>
    <name>A0A9P6EFY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_906881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFY6"/>
    <dbReference type="OrthoDB" id="3054145at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040339201" evidence="1">
        <location>
            <begin position="19"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9462" checksum="BE9E84DD136ECC13" modified="2023-09-13" version="1">MKFSLPLIFLACAHFVTAQETEDPGIEGWNEVCGTFIGTKNCTNTVLSCCYLWSDYGVCRVKCPEFGSVIPEPEPIPPEYEDPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG58</accession>
    <name>A0A9P6EG58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_894630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG58"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39770" checksum="A6F0D1D138DA88EC" modified="2023-09-13" version="1">MHVENTPGPSIFNQQLFPDRWLEQAQAWHILAEQDILLNQKFHTGANITALAFAASFALTIPQPPTISFLARGGFNQIIRGISRVPQTVATTTFARYVLGIPTPRILAWNADESNPACTPYIIQEFIDSAVDCCKAFCEGNEDERMRILEDLADWHARFLQLPPPISSGFEYGDLEFAPGLLDDANPAKSNCYCIQPIIRPSEACGETYGNGRNCGNGEYLDKEGLHVNDGDAESDALVSLESFKDVAERVRLFSKEAIHTLTNHPVLGLPCLVQEDFAFSNILLDPVTLKIKAFLDLDDVHDLPFVMGINYPEEISIADAQGLPVGSLSIREGDFGRDFPPSAYDDPLRAFDQKGNLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGP9</accession>
    <name>A0A9P6EGP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_791773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGP9"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052055">
        <property type="entry name" value="Hepadnavirus_pol/RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050:SF7">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="473" mass="53594" checksum="E8932FC1F7AA4D2A" modified="2023-09-13" version="1" fragment="single">MEDQAIHECGKDRFSEPFPTLLPGMYCTPVYAVPKPHSNDLRMVMDHSAGEFSLNSMINHDSVTGFPLDNLTQLGDILIRIKSMYPNDESIIWKSDISEAYRVCPMHPAWQIKQVVEINSKFYVDRCNSFGSSASFAIFICVNALITWIAKNVRNISCIVTYVDDSSGCTFSGDVSFYKPYQKFMPSPQVRLLTLWDELGIPHKEKKQLSGLTLPVIGIDIDPNVPSFTLPNDARLRLVTELKLWSASKGFNDSLKRWQQLSGWINWALNVFPLLRPCLNRFYPKMHDKTLLKGNIYVNGAIREDFKWATEKLDTSSGIFLLKSVDWNITKATHIIYCDACPSGMGFWYPNLHLGYLADNPADDDGLIFYFEALCVLCALHDASKRSPKGRKFIIYTDNMNTVDIFNSLQCLPNFNIILKAAVDILYSGEHDMRVLHVPGTENIVADALSRGRLDVALQTDPSLKVTTFEPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHH6</accession>
    <name>A0A9P6EHH6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_852830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHH6"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="18199" checksum="86826C4DDAABC1A8" modified="2023-09-13" version="1" fragment="single">MEVFLKVTDAFRSLKETRLSGLRSPAEFFDYTRISRPADFNQATSRISYNTRYFSGNYLLIIAVLAVYALITNYLLLISLGFLVGGFALINKFAPEATQVGEHTITQKHLYTGLFVIGIPVFWWAGPFGTFFWLIGASSILILGHASVLEPGVESDYATIGESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHL5</accession>
    <name>A0A9P6EHL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine hydrolase FSH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_852239</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHL5"/>
    <dbReference type="OrthoDB" id="2094269at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="29246" checksum="72FC898C7D8E93C5" modified="2023-09-13" version="1">MANPVKRVLALHGYSQNAVVFSKRIGALRKESNELEFVFINAPHLLQAADLHGEQSQADAEPGSLADMQSNPETAMRGWWKANKERTKVTGLEESLLAIREVLKNQRFDGVFGFSQGAAFAAVISSLLERPELYKPFQVDGQPPHPPFEFCVAISGFRVLDPFCDPFFTPHYSTPTLHVIGKTDVVVINERSRHLVDVSANKRVEEHEGGHFVPSKSKWRKFLAAYMRDSSAPLASPTAISESATSSGTSTPNAGMSYSNAVLMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHY0</accession>
    <name>A0A9P6EHY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHY0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="427" mass="46973" checksum="BC5B1C3744C445FD" modified="2023-09-13" version="1">MSSSINCFADREALHKLKMHLAMARLRSALRATLITGKTNPCFFTVPLHAELDICLGLLGVAYATGYQLTVPPLLSFLAQERFWHGEARAGFFQDLESLLHTDFSMIRDESIIHEGGDYELWWKQLPGFPEHCRPDSFLLEQQFCHYIKELRQQGYDLPSPPASVGKSVQHPVIYPNWQLTARGLSSRFKNREETFSMLAAAAANVAQAAASANSLPTTSASTDAKSAASDISILPSPGPQVCPDEEPLPSPAPDCPSRFLESSLRIVNSLRVLLHLTMISLDETHVFTQAAMVRSVESADRSHHAVACIADLRAMHQRDAPGFQHGDESLSLTHSSSLPHSPHLLSSEIPNAMPPGFPLTSSMLSQKEPSSPTELTRSMDSDDEDPGSEPSNSTEYLHDDEYNEVPDESDVTNSNSDDEFSNDTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI05</accession>
    <name>A0A9P6EI05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleolar protein 12-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_852662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI05"/>
    <dbReference type="OrthoDB" id="551633at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019186">
        <property type="entry name" value="Nucleolar_protein_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09805">
        <property type="entry name" value="Nop25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="26618" checksum="E1403C06BBFA9A64" modified="2023-09-13" version="1">MSTTNLDLLTKSHRAISAKRRAKQNQVKEVVFDDNARREFLTGFHKRKLAKAEAARAKAKEKDKQDRLELRREKRRLLREQAHENASQVEKAYGADSVEQDDEWHGIADSSQQDELARDEEYENEEILATVTVVEDFDPDTLIHGPSRPESSSEPRPFHSDHDIRTPRSQPTSRSTKKKMKSTKIRYETKDARKREQVKQRARRTEKAERAGGKASRKPSRGTKGKSGSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI93</accession>
    <name>A0A9P6EI93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI93"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="13008" checksum="92C55E1C6350DEA9" modified="2023-09-13" version="1" fragment="single">MESSPFVFISIVFCFLLPLSLISYPTSIPFLVSDIPRNLTTIPSRFDIHPPSLTLTTRPSPLTFSQAHYYVTTGSFILYRSFPPPSRYFQDSNWRQSVCMLNHWVSNIPNLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIA7</accession>
    <name>A0A9P6EIA7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIA7"/>
    <dbReference type="OrthoDB" id="27214at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040421922" description="Tail specific protease domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="698" mass="78475" checksum="31D65F2FB0591BFD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJU4</accession>
    <name>A0A9P6EJU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_788406</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJU4"/>
    <dbReference type="OrthoDB" id="300289at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041545">
        <property type="entry name" value="DUF5601"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18151">
        <property type="entry name" value="DUF5601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="351"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="752"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="798" mass="86567" checksum="DB5E6734F2D4BCCE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK48</accession>
    <name>A0A9P6EK48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM8</name>
        <name evidence="11" type="ORF">CPB83DRAFT_763601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK48"/>
    <dbReference type="OrthoDB" id="10263346at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000027">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="10384" checksum="B97B8698E0943722" modified="2023-09-13" version="1">MSLQGYTDRRVLLVLQDGRAIVGVLVGFDQKSNIVLSDCKERVYSADEGVEEIPLGLYLVKGEMVCLIGEIDEAIDSSADLSTIRAEPIPPIRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK92</accession>
    <name>A0A9P6EK92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_848820</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK92"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="102"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="12">
        <location>
            <begin position="495"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="563" mass="61926" checksum="61D5492DF48914AD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK95</accession>
    <name>A0A9P6EK95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_187197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK95"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="753"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="835" mass="87476" checksum="B649887647D1A08D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKK0</accession>
    <name>A0A9P6EKK0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_158098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKK0"/>
    <dbReference type="OrthoDB" id="3014077at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="105"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="536" mass="59925" checksum="8D5831F88BD50335" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKQ3</accession>
    <name>A0A9P6EKQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_143443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKQ3"/>
    <dbReference type="OrthoDB" id="3012488at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="160" mass="17610" checksum="9A305E9917048E82" modified="2023-09-13" version="1">MVQDSQIRRFAWTIDTFNPLAVVVDSLIAVSICVLLYKNRTGIERTDNLIHTLITYTTGSGLLTSMVATAALVVSLVFPRFIISLALYNINCQLHVNSLLASLNARRSLRERCDPSVVPLAMKKPRTLQSSNDTPQQQTSMSQIVFSDGIAHDLGMGKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKV1</accession>
    <name>A0A9P6EKV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_850140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKV1"/>
    <dbReference type="OrthoDB" id="5559898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="903" mass="98320" checksum="8DF30FE0A85A4AFD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKY5</accession>
    <name>A0A9P6EKY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_810280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKY5"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959:SF119">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="700"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="994" mass="110722" checksum="CEEA95640C0126DC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELN2</accession>
    <name>A0A9P6ELN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_761509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELN2"/>
    <dbReference type="OrthoDB" id="3239304at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="22678" checksum="D77A8E5AA060DB61" modified="2023-09-13" version="1">MPDGDEGKGGPIGKTYIFRVIPSRIGVAFISSLMFVCSISMAVGASLIANRLDGQLTPVQRLAIIFQVLNYLFVALASMVGLYSLISILHRNAISPLSRARKACQLFCGLLLGHLPFSIASGALSIHIVFKATTRALRVGIETAERKAGSPLYWICTKTQLIKGLIVVLYLALWFLEVVALYAGTRYSAQLHSVEMIKNVEDEEAADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELQ9</accession>
    <name>A0A9P6ELQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_760781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELQ9"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="333" mass="37379" checksum="29DBB9AA01759CF3" modified="2023-09-13" version="1">MDRQLFALLQGFFCLTPIPDLLLPQGLDFNTLLDFFITHILVNSHSKKYPPSTQYQKRFWKWAIEHLECMLLELDNNSNSEVDSQIYDHYMMLSIEPASRREILQLEAPTPSYVTYFWRRKGLASPVESVDLSDYDTITLLESRTTVENGKTGLRTWLASFALAQYLCSNPEIVAQEAVLELGSGIGFLGIVIANLQQDLMGGRGSLYLTDSDPQIVGRCQRNLSLPCNRSSAHSNINCLELDWKDSVCYSGESPLVALLHQKIKPNIILGADVVFDPSLILYLVETLRTGLQGEATTALIALTLRNLETLSTFRSALNGELSFRCPNPFSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM69</accession>
    <name>A0A9P6EM69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM69"/>
    <dbReference type="OrthoDB" id="2576538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="31588" checksum="48D407D1A638D591" modified="2023-09-13" version="1">MSAPEVAAAPVPVPTEEVKPVEALVEPVAEPAAAAAAAEEPIAVAPVEAPAVTEPEVAAPAPVEPIVEAPKDEAEAPTVTEAATEEPAKEEAKPAEAETKKEERPKSPGLLAKLLAPFKDGKKSEKKEKVKTAKKEKKKEEAETSASAEEAPKEEAAPVPEAPVVEAPKEEVAPVEPVKETETAPAVEAPAVVEPEAAKEEKKEEKVEEKKEEKKDVKAIKIGRRLSSRVGDFFKSKSPKAEVSAPAKVDEHPPKIDEPTPVAPLENPATESTGAAPTAEPSTEEPAKTAEAAPLAAPVVAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMS7</accession>
    <name>A0A9P6EMS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_848114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMS7"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="201"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="545" mass="59880" checksum="D8C2669980DCDE56" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN23</accession>
    <name>A0A9P6EN23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_874484</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN23"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF65">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="541" mass="62400" checksum="A4E068445AE500C9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENJ8</accession>
    <name>A0A9P6ENJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="4">1.1.1.100</ecNumber>
            <ecNumber evidence="5">2.3.1.41</ecNumber>
            <ecNumber evidence="3">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="30" type="ORF">CPB83DRAFT_903512</name>
    </gene>
    <organism evidence="30 31">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="30" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="30">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="23">[Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="30">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="4"/>
    <dbReference type="EC" id="2.3.1.41" evidence="5"/>
    <dbReference type="EC" id="2.3.1.86" evidence="3"/>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4251012at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03447">
        <property type="entry name" value="FAS_MaoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.20:FF:000005">
        <property type="entry name" value="Fatty acid synthase alpha subunit FasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000078">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.100:FF:000001">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000006">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2490:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.25.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3330:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit beta dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000003">
        <property type="entry name" value="Fatty acid synthase subunit beta dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013565">
        <property type="entry name" value="Fas1/AflB-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041099">
        <property type="entry name" value="FAS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040883">
        <property type="entry name" value="FAS_meander"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08354">
        <property type="entry name" value="Fas1-AflB-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22235">
        <property type="entry name" value="FAS1_thioest_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17951">
        <property type="entry name" value="FAS_meander"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17828">
        <property type="entry name" value="FAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="20" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="21" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="18" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0521">NADP</keyword>
    <keyword evidence="16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="31" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="17" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Carrier" evidence="28">
        <location>
            <begin position="2219"/>
            <end position="2296"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="29">
        <location>
            <begin position="3148"/>
            <end position="3709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="27">
        <location>
            <begin position="2653"/>
            <end position="2673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="27">
        <location>
            <begin position="2657"/>
            <end position="2667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00033756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="KAF9532470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="3937" mass="433189" checksum="0E443E7D6EFAA2EB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP22</accession>
    <name>A0A9P6EP22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP22"/>
    <dbReference type="OrthoDB" id="2553298at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027911">
        <property type="entry name" value="DUF4604"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15377">
        <property type="entry name" value="DUF4604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4604" evidence="2">
        <location>
            <begin position="14"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="213" mass="23717" checksum="7E4A09F1B2CABCA8" modified="2023-09-13" version="1">MAPREPTRAQLSSKLAYQSHTPSFLQKLQNRMNGIQEDEDEYEDEEFEHVGDGREPIPRRPRPAIPERPEGDPGSENEDDVDEKPQVVVLRAGKHLTEREAENVRRAEKGLPPLPNPETIKETSDSQESKSKELATSSSTKSTSNGLSFSSSSTAFKSKKRKAPGQLDELKFPELEEKKNDKDKAGGKKSSKKNLAKKAKKESKTLLSFGDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPD2</accession>
    <name>A0A9P6EPD2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dicarboxylic amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_846624</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPD2"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF9">
        <property type="entry name" value="DICARBOXYLIC AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="48"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="555" mass="61654" checksum="AB8EF4FCA0C7D29E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPP9</accession>
    <name>A0A9P6EPP9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_758920</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPP9"/>
    <dbReference type="OrthoDB" id="8918678at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 central conserved" evidence="10">
        <location>
            <begin position="35"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="9">
        <location>
            <begin position="228"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="561"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="841"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="590"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="681"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="725"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="775"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="949"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="958" mass="101355" checksum="DF5CE9DEACF5AC43" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPT1</accession>
    <name>A0A9P6EPT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fork-head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_807158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPT1"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="4">
        <location>
            <begin position="74"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="2">
        <location>
            <begin position="74"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="216" mass="24540" checksum="97CC315F96E7B55F" modified="2023-09-13" version="1">MYAPSPAGSDSSLEESSGSAYSSSHSQSPSSLGPTPISMALPTNQETEEYLRRTLEIPPHLPIDLRALPEPTEKKQPPITHMIKLAIWGSKHKRLTLRQIYDEVERRYPSLKDLQDKPWQRSIRHNLSLKAIFVRVERPTSDPGKGHYWAVDIRQGEGNKRDRKRKDTSGRASTSRSEDDEEFSEETEDDRSSFVMLGGRHGDRRGMSSLTTAHFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ12</accession>
    <name>A0A9P6EQ12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_758462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ12"/>
    <dbReference type="OrthoDB" id="3235960at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="3">
        <location>
            <begin position="45"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="18669" checksum="9D39A46310F5E931" modified="2023-09-13" version="1" fragment="single">MSSPVSPNQELTPTIPLSEGPAISPTGPFVTSLPGTVGADVHDQWLVVTEHLREKETERCEVWKDEVQSILVFAGLFSAVVTGLLVDSYKSLQDDPSELLLSSIVVQLAYLANNSAGITASPPDPAKPVRTFPLTSDSPNKVVNTLWFLSLVLSLTAALVGLVALQWLREHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQR3</accession>
    <name>A0A9P6EQR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_846072</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQR3"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9533215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="521" mass="59924" checksum="87FB06B3BEDA2947" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA6</accession>
    <name>A0A9P6ERA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="6903" checksum="51834C024035CCDE" modified="2023-09-13" version="1">MATNESWVPTINCCALFYPPPLIASITSLEVVRSAHSIPSHASYPRSTSSVHEADDANHHNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERB3</accession>
    <name>A0A9P6ERB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_207718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERB3"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033167">
        <property type="term" value="C:ARC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="625" mass="69093" checksum="1C6D007D132B232F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESB0</accession>
    <name>A0A9P6ESB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESB0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8549" checksum="162E3E38F6858C4E" modified="2023-09-13" version="1">MLYKSWKVRNISTVAAHVASNATRNERAPFSMAWSINGSLRVEKQMKTKCIWWRSTFSILYTIFVAGGMKHKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESS6</accession>
    <name>A0A9P6ESS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_902232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESS6"/>
    <dbReference type="OrthoDB" id="2430277at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02205">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="358" mass="35858" checksum="17A934C72F660741" modified="2023-09-13" version="1">MASSDLLKAIQAGKKLKKAETHDRSAPIVEAPKGGSGGGGGSVKSSGGGGMGAPMGLPSAGGPPQLGGLFAGGMPKLKPAGSNNLAKPPNLGKPPSIPKADSSAAPAPPVRSIPTKPSAPPPPPIGRPPKPSAPVPTPPARPAPALPSRENATGTTAPPPPRRAPPPARASSPPAPPARPTPSLPARTGSPVKPLTPSRSVPMIPPRNNSPSGGSPSKSSFGRAPPPPPPRPSSHLPPSPARTAPPPPVRKPPLGVPAPPPRPRSVVETQTEDRRSPSPVSAPSSRFSAPLSRAPPPAAPSTNGRPPPPRRKIPSPPPNAGAHTFPVTDFPPPREFKAAVRSYPSGGQHGSNFDLGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETP2</accession>
    <name>A0A9P6ETP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like-conjugating enzyme ATG10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_901785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETP2"/>
    <dbReference type="OrthoDB" id="4089664at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061651">
        <property type="term" value="F:Atg12 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22539" checksum="E8C35AEB6835550E" modified="2023-09-13" version="1">MFTRDQFERACQVFAKKHSQWKWASARNPGYGYLMRTTTHMRKSFVQTDELAELVEDLEEGVEVITSADLASSLTVNVVENIVYCASFSVPAFYFAVHNSSGAPLPLNEIIQTSFFKISLPKDATSNDFALTVPSGSFPLLSQGDHPTLGAPWWYFHPCETDKAVGEFMKEEDQALCEDERLIRWMEIWLMIVGNVLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETT0</accession>
    <name>A0A9P6ETT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Survival motor neuron interacting protein 1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_211992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gemin-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETT0"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794:SF0">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794">
        <property type="entry name" value="GEMIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="43275" checksum="1FC78FCCA5684BE4" modified="2023-09-13" version="1">MASLKRKHDELDESDEDEPAYGKQILPVANLPNDFNEEPVDGLQYLFTVRRDARQRPDVIRAPNPYSQADSLDHEPSEDVDVESLQLPSEEWREQFEYRFLNFRKNIKQPTIHVGPPNHGSRRLMPDKKDRDLWWAFLEGQPESDWTPVAKSNSKFQKPSRPPRGMRAWADDPQPRRNLVSLHDTSLMNDEGEVEQVLRVDPAESLPSPAGTPIPLDYLEGAMQPGSSTSASGYSAVLRLNLQPPREPNTVLLTQIDEKMAFHLLMYFTHWINLYLKAPDVDEHIPKDSHARWIFALLSRVEDNVFADDMNLLRNLARACLGLIEEKFKNENSASKSILRCRMSESSCWLIFTLVADVWKQRDLWQDAEAAMRSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETZ9</accession>
    <name>A0A9P6ETZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETZ9"/>
    <dbReference type="OrthoDB" id="2355659at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="36256" checksum="5355689A5AF7E57F" modified="2023-09-13" version="1">MHRLFYRTASTLITLFGSVANVILTIQLVATWRSLKWEQETEWEGLGEKWQLHGLKLIWALLCLYFSSSAAVSIVGLYGVLKSKASHVRFYRDYSIADFAFSTTSTLLASYAAFLGPARAGICEEFSHHPELMRDMLEMGLNLENCELWLERAVFAMIAVMFVIMVVRLHFLLAVSNYYSQLVRWQCHHHHRSPSNSSPSSAISHPLQRIVLVPTAAHPVDLEGQNSADLVYAAVPRASLPKELQAQATEAWVSTTSSNSNSGDHWHSHRSHHHRRYHHRNHSSHHRRSCSREATGLIKLDIAPGEGLLPAYALQDEEAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUJ4</accession>
    <name>A0A9P6EUJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_830590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUJ4"/>
    <dbReference type="OrthoDB" id="660550at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040196564" evidence="5">
        <location>
            <begin position="19"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="78"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="405" mass="42338" checksum="74ADBC1B4B98CD36" modified="2023-09-13" version="1">MFPKTLLSTLLLALAVSANPVLVDKAPVTLGLTRRLNLTSVHNLVRHDQTRAQKLKAFGGVSTDAVINEPVDNQAVTYFADVTVGNPGTHYSLLIDTGSSNTWLGANKAYAKTSTSKATSNKVSVTYGSGSFSGTEYTDQVSLGSGLTIPSQSIGVASKSSGFDGIDGILGIGPVDLTQGTLSPATSSTIPTVTDNLYNLGIITSNAIGISYAPTTSEEVENGELSWGGVDSSKYTGSITYVPITSTSPASFYWGINQSIKYGTSTTILSNTAGIVDTGTTLILLATDAYKKYVAATGAVLDNTTGLLKISTTQYSKLQSLFFTIGGTSFELTANAQIWPRSLNADIGGTSGSIYLVVADLGSNSGEGLDFINGYTFLERFYSVYDTSNKRVGIANTPNTQATSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV35</accession>
    <name>A0A9P6EV35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_878765</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="839"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1016"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1056"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1090"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1122"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1156"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1209"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="459"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1269"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="784"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="793"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9535634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1591" mass="174227" checksum="B538C1F84FDF2566" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVM3</accession>
    <name>A0A9P6EVM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_34779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVM3"/>
    <dbReference type="OrthoDB" id="10267139at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="459" mass="49976" checksum="D86388BAA21B17A8" modified="2023-09-13" version="1">MSNQRLTVSNRHGSPGSSIFDLPSQPVHSNLSSSNDLSLGSTYHVIEQPATTPQTGDPSFIIISGGTGGNAICTAFKNACYVLPVSDDGGSSSEIIRVLGGPSIGDIRSRLVRLIPQAPLSSPLDSIRSFLAYRLPRQCTQREAREEWRDIVEGRSALWKGIPSDRKETIRGFLVYFESELLKRAHKNFDFRNGSIGNYFLAAAQGFFRSLPSAIFLFSSITSSQAHILPVIVTNHTVTIAAELTDGERLVGQCEISHPVVSTELSFRVTSDDAPESPTEALGEVIASKQNIMFESMAKGTHEPLPSRINRLYYINGYGMEIHPSPNPDFLSNLGSRDILVYSCGSLWTSIMPCLALRGVASAIARSSSVRVKVLLLNTENDRETDGYSAEDYILAIARTLNTNYSTPAYGLGGANTIYPISAFITDVVYLKGTSVAVDVEKITALELAMRQVWADRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIG1</accession>
    <name>A0A9P6JIG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157968">
        <property type="protein sequence ID" value="KAF9521989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIG1"/>
    <dbReference type="OrthoDB" id="3061143at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="22821" checksum="B74E45980FB61537" modified="2023-09-13" version="1">MSYADIVQGKPSVVQPQPQQATQKQVDNQVDAQFAWSVLGQPHIDSDDLPAQPTLIDLATGRLIQSSSIQNQPDSPKDMPTQSRPIPIRPGNSLVQLNANCDKALPDIYLALKHPFQRRHRKVYFYIQDLSKAGLRRTLDLENRLKIPHGSHQDTINAGFLHMEENDIIFMMLQLLGETEGASLPIQRNMLLYAQEMHASGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIH9</accession>
    <name>A0A9P6JIH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIH9"/>
    <dbReference type="OrthoDB" id="3270344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="719" mass="81005" checksum="F4408BCB87B8AEC2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJT8</accession>
    <name>A0A9P6JJT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJT8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="197" mass="22831" checksum="332C9226C2D88FDC" modified="2023-09-13" version="1">MILRDGMMLIFSVSKTPEMAKHCICNTFYNPQRQRQRYCEICCRWFCCRCLVQVEPVHLGEGLAERLSQLPIERGWKWSEKRTAFDNFSIVGTGLLVREFRRKMSSVTNTSTSTVTLDDCETLWDSDRDNEGSPEIIIGRKKEAVKKWARKNRQTDPIEFRLTLLLGARFCRGILSITEGHHFLKRYVCPGGCSKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKE0</accession>
    <name>A0A9P6JKE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_820499</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKE0"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040513114" evidence="3">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="198" mass="22304" checksum="36F6449CACD34C1D" modified="2023-09-13" version="1">MFPRASCIGLGLLVLSSLGVFLVARKSGNLYPAIDRGHIYTYIGSDYPLEWPIPSLNTVHMSLENSLHYAFDTTQGRAEWNTTLPSGGALVYLGPHKRPFTLGMLHQIRCLGIIREILDDFYADDSPNAKVDRPHLARHCMNYIRQMVLCNGDLRLENVRAAKGKRLTVPEVTHTCKDWSAVYAAADDNFHELKLVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKK2</accession>
    <name>A0A9P6JKK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_644469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKK2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="110" mass="12055" checksum="B68FE70C8A480ABF" modified="2023-09-13" version="1">MLNTLSCCVLGTFFFISSAHSGCGWIFLLGSVQRRAGGRLSVRYVPLLKIWLDSVMGTTGITHLHARTTMDLVQNTNTSLQQSGATKTKELGFSKRQPKISAQDLVPENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLP1</accession>
    <name>A0A9P6JLP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_554040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLP1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13548" checksum="14F5706733922E23" modified="2023-09-13" version="1">MFDLNLANTCDNCDKHLAAIHGLSKEPVCDRCLDVTTLRTCDCHESRDCQKSHWREGHKEECAELLRVAELSESYGSIVVAQRRSIIRWSKKNRAILNAGSVFALEVGTTEDKSRRCSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM22</accession>
    <name>A0A9P6JM22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM22"/>
    <dbReference type="OrthoDB" id="5271586at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="259" mass="28054" checksum="A2787CC4063B691B" modified="2023-09-13" version="1">MVLFAFSSTPGNGYVISSGDSSAWKSIPEGLSAKIKATAAAGDTVLSVSIGKDDWFINTSNFVYCCPSGAVTSCLSSAQAQSSNVRLADIEQFVFMPHTPTGYFCSTAKTSMWSGLPTSMAENLRLSSSKADIRCVAVGAGEQWIIVREDNSFAYNGISDDLEKTLKENHAASKTIKYITFSLDNASYYFVVYKDGSTVHLSPAAWHPQIKEYIQKSQERDDDDDDDDDDGAALLDLASFNADIQSIRNAVSSVQMHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMY1</accession>
    <name>A0A9P6JMY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_837117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMY1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="21041" checksum="2C22ECAAF326DFEB" modified="2023-09-13" version="1">MEGNKKQFYADVPDAANGQPQSQKHFLHQKKLLDFHLFYLGPLVSQEGLPGRLIKSRKENPWFGSWYDEGSKKREVDVAEVGLSRHGAGKPQVENVVPRLGRCRASVFCQLEGKQPLPTLGLDVEGSPRRNVVTWPQGFDLQESTDKTVRGDLTGQRADLSPYKSKIAQESSTRTDLWLLQNKKSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNG3</accession>
    <name>A0A9P6JNG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3752 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNG3"/>
    <dbReference type="OrthoDB" id="73491at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3752" evidence="2">
        <location>
            <begin position="191"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="38754" checksum="346B9DBA98EAA2E8" modified="2023-09-13" version="1">MSSIGPQIPAHLRQQLQRPQDNEDDEDEGPQPLGPRIGPTIPGPSKVAVFDEDDEDGSPQPKIKPNIGPLIPPETSKSSKKKGHANEVGPVGPSLPPQIRPSKKESPPPGNKRILGPSFPSYAPTYNPDAYLEDDDDDDDDVGPQPLPAGMQHEQKDAVKEFMEREEKRKKAAEDALKPKAPKRDEWMLVPPTNAGLLANLDPTKLKGRQFSRGTTAPSNSDTSLWTETPAERQQRLADEVSGKKRRVTEAPVEDEDEVIRKRRRKQDEEVIRKGVNEHTRSKRGAALVEQHADTLTKKPTDKEVPVIWDHSRDMGLGGRLMDDDKRDKMLKEAKGLGDRFGSGRSGGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP99</accession>
    <name>A0A9P6JP99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_354315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP99"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="18069" checksum="93BDC1713F4FED91" modified="2023-09-13" version="1">MALRVWRNTDILIFQTSAALSDWTIFLFYAVPLGVARKLYTGTVGQELLLFPSNLMNPKMFQLRQWILMSISFFLEQYSHQYDKPEVRCRSMSSNRSPCSSWRRWLAAGLIFSTAHSSTHLKFRSSNVTESTIQSSHILSRLFWHRKYKLNRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQI7</accession>
    <name>A0A9P6JQI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_766445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQI7"/>
    <dbReference type="OrthoDB" id="3241054at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF1">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040477710" evidence="1">
        <location>
            <begin position="23"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="16220" checksum="8A68E801C5FA2889" modified="2023-09-13" version="1" fragment="single">IMFSKFLTSTTLALAFLSQVNAHTGISPALGVSGTLQHSDVKRPSTASPCGAGVTVAAAALDSSTAVTAGADGSVTATALNFNAGSGGSRKVTAKVDATGQGKTFVAMTVTTNGDAAPTYYDPQTIVAQLPAGTKCTGGATGNKCLVQFVTTAGFGNCVVVQQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRJ0</accession>
    <name>A0A9P6JRJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_925410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRJ0"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF3">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040466757" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="35"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="389" mass="42744" checksum="5DB68A53580F2855" modified="2023-09-13" version="1">MAFPLILLVVGLFVLPPARALIRFGCAQLVTERFDPLVTPGQVSPHVHQIIGGNAFNLTMQPDFDVPGAATCTTCRFKEDKSNYWTATMYFKHPNGTYLRVPQIPNHVIGSPKGGMTVYYLQIAQPGEKVTAFPKGFRMITGNPMLRSKDTSDIRNVTKVSSWATTFRCWSDEDFLGPSNKYPPGAGEYDTVHLPNGKCFGGIRANIFFPTCWDGKNLDTPDHHSHMAFVEGKVDPNMGIIAQNGTCPSSHPIRMPAILYETYWDTRPFNDMWPTDGTQPFVLSMGDPTGYGQHGDYLFGWEGDSLQRAMDNCTDGFGTPENCHELTVLSDDEINKCTVPPKVDEKVEGDYLSALPGCNPLQYGPGPATMIQGCTAISTTSFPTPTPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRN1</accession>
    <name>A0A9P6JRN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_148912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRN1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="172" mass="19899" checksum="2864146FAB8A8E4A" modified="2023-09-13" version="1">MSEHPLRDFFDKWSDTFTYDPSEPSTSEFRRLCREQRWRGENPAKTEAESQFRYAITMQFNRNYGTDVNSLESWQRLCENVRINPIPDNVKEARQKVKQTHVNLVDLTDGYDGGREIIIFPTEEALAAYTRSNGRFFPKEEAYAGGVLKYLLRHILNPYLGGGRGRGRGNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS81</accession>
    <name>A0A9P6JS81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS81"/>
    <dbReference type="OrthoDB" id="3168922at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="220" mass="23832" checksum="3B7F933E5063C182" modified="2023-09-13" version="1">MAAINVNRQAISAAFSRGGSSRLVHTSSRRRAVALSATTHVSPQIEEITLQPIFDIFDAPTRLSETSEFIRAKYKASSNAVKASTSYTTTMFPSSYSMESKYHPTTLPPPIVFDGPARPRNAALALKARMRQARLTPSARGSSRPVTSSTTIGASSTRLFSSDTQIEMFDGPARIMRYHHNPSDSDRFGSIPITKLAFALGVAGTIGYATTLAKELETSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSI4</accession>
    <name>A0A9P6JSI4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Complex I-ESSS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase ESSS subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_848152</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Complex I is composed of 45 different subunits. Interacts with BCAP31.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB11 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSI4"/>
    <dbReference type="OrthoDB" id="2147978at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019329">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ESSS_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637:SF1">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10183">
        <property type="entry name" value="ESSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9531992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="117" mass="13261" checksum="4281EEEA07593D02" modified="2023-09-13" version="1">MLSSATVGRGIRATSCRLPRATGRRYGSHEAPQYNEPSGWLFGEKPPPPGQKRVKEDWENIWYIGMFGTMAFASVLLYYKPDTSIQSWALREAKERMEARGEKFQYEPSSTQSTPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSM5</accession>
    <name>A0A9P6JSM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSM5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="8788" checksum="50E56A60F6DE4E7C" modified="2023-09-13" version="1">MSNEACGICCIACADVCAGIILDFITQRHSCTETLCTCCCGTCCCDTEGADDIRAERAPLLPEVGPSQAHQPRAVPQMKATHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSQ9</accession>
    <name>A0A9P6JSQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_850056</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSQ9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="9"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20131" checksum="AEA10BA021AA458B" modified="2023-09-13" version="1">MSIYSLFKILRTVLFVLASLVAVGVAVLASLSSSTIPHELPGEYWQPVVFSLAVGAMTILTLPLILFSSTGQRKGGFHTRVIFELPWTGILLILWLAAGLVLRSQFTKNHCQFADYVSDKNEYIKWGKDVCSRWNVLAVMSFIDAACPAILVFVHSATLLALALGSKSRGKDNVWGSQTRDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTJ8</accession>
    <name>A0A9P6JTJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein F37C4.5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_759238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTJ8"/>
    <dbReference type="OrthoDB" id="10068793at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02231">
        <property type="entry name" value="mucoidy inhibitor MuiA family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005:SF8">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4140" evidence="2">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="1">
        <location>
            <begin position="194"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="63902" checksum="9A70A3AB2960120B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTP1</accession>
    <name>A0A9P6JTP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_750460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTP1"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="8">
        <location>
            <begin position="5"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="19266" checksum="589C3A5733BC3A18" modified="2023-09-13" version="1" fragment="single">TQVDESKYEVVYSDGACKGNGKADPVAGIGVWWGHDDHRNLGERCPGEQTNNRAELIAILRVLEETPISKRPLLIKTDSKYSIDCLQNWFGKWSSTGWKNSSGQPVKNRGVIECIDKMIKIRNWKGQAVDLVYVKGHSGHVGNDGADFMANIGTTKSPLPDRDWEALLQKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTV8</accession>
    <name>A0A9P6JTV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTV8"/>
    <dbReference type="OrthoDB" id="3242721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="22361" checksum="47B7276F981B3489" modified="2023-09-13" version="1">MSNDRPIVIAPRPVRLASSLFARRQDATDFSFIADIRRDSTSPDSAPDRHSARPPSSSALPSEALDEFLSILRPSFMRKPRPVPFPAFLNPDRPLALRSFPRVESSPDPSCAVNNSSPVNVPDDHLLTPSPSQTDDIKFVQPDISDARQWFSSTLLSSPISRFHTRNPFPRQVEDSPAPMTPLSPASIPLPAPSPGEMMLENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTZ7</accession>
    <name>A0A9P6JTZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small GTPase Rac1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_52614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTZ7"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01871">
        <property type="entry name" value="Rac1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000088">
        <property type="entry name" value="Ras-related C3 botulinum toxin substrate 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="21436" checksum="1EE1B2C208FF3F18" modified="2023-09-13" version="1">MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKTISLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPPSYENVRTKWYPEISHHAPSTSIVLVGTKLDLREDPATIEKLRDRRMAPITYSQGVAMCKDIGAVKYLECSALTQKGLKTVFDEAIRAVLNPPPQVKKTKKPTCVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUI9</accession>
    <name>A0A9P6JUI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_758932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUI9"/>
    <dbReference type="OrthoDB" id="3254913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="8912" checksum="36757D2BCAB49181" modified="2023-09-13" version="1" fragment="single">LPEIPSADLTFDFSSFMDSSQPEQEKVAKRASNVQKLAKENEKLQAELKAMAERLEAVERKRVELAEKEQREGKQSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUK2</accession>
    <name>A0A9P6JUK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sucrase/ferredoxin-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUK2"/>
    <dbReference type="OrthoDB" id="10253744at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF14">
        <property type="entry name" value="ACTIN PATCHES DISTAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="40445" checksum="B680853414651E68" modified="2023-09-13" version="1">MFVHKLRSLVLGAPEDSDVLCRSLRASDVPVSTADCRACADPCDLGHDAYPRRFNVDMASNMLGSVDPYHRQLVISTGKADWDRKIEDDKDSLAAALGQVIARPPPPPPVSTSPPLSTSPKPSTSPKLPSSPPNPKGIRSGTGLFSSSDSTSTSVLNGSHRTVSEEEDDDTVLIFPDFKCVTEVSRSQQGARDLWNTAVDPSIGREGVVLRRSPLKSWVLPYGCVILLCSHKKRDNRCGIAAPKLEHAFIKSLEAHGWDADTHLEHPSLTMGPALEDLGSTPEEREETIATQLQESTSSKRALIVKVSHIGGHRYAGNAIIYTPAGSGIWYGRVTPHDVDSIVTNTIVDGLILPPLLRGGVNLSRPNCKTLNDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUY7</accession>
    <name>A0A9P6JUY7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_903453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1880850at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051278">
        <property type="term" value="P:fungal-type cell wall polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056261">
        <property type="entry name" value="FKS1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23605">
        <property type="entry name" value="FKS1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1223"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1273"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1378"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1484"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1521"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1557"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1587"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1661"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1711"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="12">
        <location>
            <begin position="224"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9532970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1751" mass="199236" checksum="E4AE417947E5CF3B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV26</accession>
    <name>A0A9P6JV26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV26"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7556" checksum="EC939F84C80383B0" modified="2023-09-13" version="1" fragment="single">VARKVYICSQTNQIDTQQAAMVEKSHPPIAACFGDESGTMVRAEQCFALLPNLSSWHLINHIHSILYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVM9</accession>
    <name>A0A9P6JVM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVM9"/>
    <dbReference type="OrthoDB" id="2831072at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="21984" checksum="08EEA62289C67ACA" modified="2023-09-13" version="1">MLHFTGASSVQEILAASISPSITSSISGNAPAELKGMAIRWYDLLHQRGGYVRQIREKLTITEISLVSKPGEERGAQVKMVCELDVAPETCSSAGILDVGCIGFLVDEGSSIALQLLSILQKGSPHMGVSQCLNLQFHGEVAQGGKIIIVNRSVSKKTDVGCCTSEVWEVTNARKLVASATHLVVPSSMSPALKQEISTRQPQARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVY5</accession>
    <name>A0A9P6JVY5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2415 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_902617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="64353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF9">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1187"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1243"/>
            <end position="1252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1282" mass="137951" checksum="ECC5258179A7B28B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW52</accession>
    <name>A0A9P6JW52_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_901558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="4">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW52"/>
    <dbReference type="OrthoDB" id="202234at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF11">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="7">
        <location>
            <begin position="102"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="285"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="41376" checksum="9976E22CA351C1A2" modified="2023-09-13" version="1">MSFLSLLIKPLAYISLPLLVARQIAVNPNPSPYRYYARAFLYVGTLMTVASCSIIAAAGMTLVGRSNDVNNFVARFFYSVASRVLDIKVDIEGEEILGTRPAVLMANHQSMIDVLILGRIFPKQTTIMAKKSLQFTPLGPFMSLAGAIFIDRGNNASAVRSIEAAGEKMKAERISLWMFPEGTRHMSKEPDMLPLKKGGFHLAVNAGIPIIPIVVENYWHIYRKGVFETGTIRVKVLPPVSTTSLTSTDVHNLADGVRESMLEVLREMSPISESESSASKAILRERTPTATAPNPTSTSKPSSQPKKKQEEPAPSSSLIESVSPVLSPTIGVLPDTVNSALSSKGSSSSLASSSFSSSRMRGSENGAETEEDEGMVLVGKPKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWC8</accession>
    <name>A0A9P6JWC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_804398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWC8"/>
    <dbReference type="OrthoDB" id="276151at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="663" mass="75698" checksum="4C50D45A87B5A985" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWZ6</accession>
    <name>A0A9P6JWZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_753476</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWZ6"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="12"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="302" mass="32527" checksum="2125FEB58D13DF32" modified="2023-09-13" version="1">MPMFDTERLKVAGVVTFYMGAALVMVFVNKAVLNNAPELPFIFLLIQLVIAVVLLHATAAVNERVKIPKIDMDTTKKLFPVVSVNIVGLVFNTLCLRGVEASFFQIARGLVLPLTIAVSSAHSRTSPPRSVMFCAGIVTFGFMFGVSPSAAVPLTAIPSTLSLFYGVLSSLFIAFHAVLIKSSLPYCNNSTIELAWWTNAGSALLILPFVVLKGEIATFYTLMYTDSWDSSVFLWGCLVTGVFGFLLCVAGLLSIKVTSPVTHMFSSAARSVLQTVLGVWIFNDVLTINRAASIAIILGGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC29</accession>
    <name>A0A9P6BC29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158166">
        <property type="protein sequence ID" value="KAF9521279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC29"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="520" mass="57330" checksum="C307B97B63C06C68" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC37</accession>
    <name>A0A9P6BC37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_932677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158150">
        <property type="protein sequence ID" value="KAF9521294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC37"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="407" mass="44241" checksum="850DBBBF6C6E9041" modified="2023-09-13" version="1" fragment="single">LAGGSGLVPWKKLREAQTTYIQAEYLPARFVMKKPRELSQGDIVRFFEHVRAREQAKGPNEAFRLEKIWDHSVGAVMESSYPLDQNRNTATAKKKATKPNGRGKGKTKKKNKTKGTVPSLPEGLLTMDASRGGTPGNMPAEMTTAASVDRSNLLGGAPVNMVARQHEASRTSAHQELQQEEASWHLTPQQRFGISGAADSHQDAVEIEANEGMEWVPAGKSTLGFLVPSGRANSPVGNSQGTSSTYGNAFPGAINPAPSVERPVDNIGFGCLNSRETVYSAPETDINASMRRDSFNSAVENHRSIAPAEPPINPVSNIDPSAFPSQRRVAPVPVQRSTLSVDDRANQILAENDITHRPRVSIGQRELRGGKNPSLREKRTSDVLALDEALKYGIKGKRISKPKQRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC90</accession>
    <name>A0A9P6BC90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_801371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158063">
        <property type="protein sequence ID" value="KAF9521444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC90"/>
    <dbReference type="OrthoDB" id="3221862at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="24114" checksum="EC6D16269C908353" modified="2023-09-13" version="1" fragment="single">MRANAIVFRHPISKIYDTLPPPSSELDEVLAVIFTGPCQPTQEDIKRTPFLVRRNQVSRALTWLKLNHGDYADIVISHENLLEYPDSDTPVCIDYRTSVINKEREAMSVHDTGEEDGVESGPCSFSVQSLTGEEYSKMNLEAIKAAALSHLMNDGKIMFVGHSSTPESMYKNSSLYPSMMPWLFPYGLGAIGQDGLKGKHSISTQKKQFLMYHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BD48</accession>
    <name>A0A9P6BD48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SUN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_900994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158256">
        <property type="protein sequence ID" value="KAF9521220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BD48"/>
    <dbReference type="OrthoDB" id="342281at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034993">
        <property type="term" value="C:meiotic nuclear membrane microtubule tethering complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="SUN" evidence="6">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9521220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="172" mass="19027" checksum="A2D70A7FCB9B878F" modified="2023-09-13" version="1">MPKLTSPTLPTGNQPGNSPYKAIDDDLRPGRCWPFKGSSGQLGIQFVAPLKLSHITIDHIPKEVAMLMQNAPREITIWGFNTSTTKTNPLYGPSLVDGKGSPPLRDKGYTFALVANLTYDIHAAAHIQTFPVSRFHEDDGAHEGVVVEFLSNWGWETTCIYRVRVHGTLEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2M2</accession>
    <name>A0A9P6E2M2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_932940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158154">
        <property type="protein sequence ID" value="KAF9521288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2M2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="147" mass="16480" checksum="4B07A9A99487EF3F" modified="2023-09-13" version="1">MPCYCTLCYPSSTFTRSTVQKHLNKDLQKRAQQQPRTDSALRAFVDGCISRNQAYLATGKTQNVPGENMEASVPRPVVEEDNLFQPNANKYSNFDVEMDELDQANLRSSLQVPDFTTDINIHVSDNAGLEKEDSDSDDSVDNISANW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2M4</accession>
    <name>A0A9P6E2M4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158142">
        <property type="protein sequence ID" value="KAF9521303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2M4"/>
    <dbReference type="OrthoDB" id="3061359at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="497" mass="54846" checksum="518A7D2946EF14FE" modified="2023-09-13" version="1" fragment="single">MTTHSTRPVQLFNPVNRRYGPPNPEMLRIQEIIFYSESRARAVLASILASNQAEVQWKKKYVYSCVGVAAASAMLIDIPVIIRSLAGDFFLPMGKNVGHLTDSIRAIVDAGVTRWDPSRTVPTYHLAWWTKTSAEVEKMPIMHRGTIEECLRVHREVLSKEIAEYKEGLVAEDTPPPSPYEYPFSAALIDGMYKPSAVRVPVVPSKDICEGCIAASEALAHNDDFLTQATHKCQGFFEAHQARANLSLRRASGFYKLFEAAVSKDAEMPFDIGLSNPTGPLARPSVMPSTQPITFDQLEGSTGNSKSAKKARAQQLKQHQLVLEIQKAAAAAFQRDVDDPRPNAHWTSGRALSTEEVTGLIRGADRAHAKDPHTGYDDRLRDNLNPDRWSPWQTATPHASDRFEPVEQRAPSPVNIHELVSSDSRMYKKFVRPEPPARPRQPALSLSPAPLTLELNHPSGAALNPIVLSDDESSALSYVGSVKGNQFGEDAMVLSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2V6</accession>
    <name>A0A9P6E2V6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_778636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158042">
        <property type="protein sequence ID" value="KAF9521501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2V6"/>
    <dbReference type="OrthoDB" id="3222357at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="8764" checksum="96266EB8A2118656" modified="2023-09-13" version="1">MGDVAQKDATGIVGHACGRHGCYVPRSVVDLQKGERQANVDWSFQECIKGMNLGSIQKILHIYDIACQYCKKLRLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E352</accession>
    <name>A0A9P6E352_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_778369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158008">
        <property type="protein sequence ID" value="KAF9521640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E352"/>
    <dbReference type="OrthoDB" id="4230923at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20958" checksum="430663C0614847BB" modified="2023-09-13" version="1">MGWLRGEGRKKFESSLETEVEIKDRMASTVLEYVPTTFAPQDETSLRAAEFVNNLPSRSIAHAKWIKPIEKHSPNQQLAFLFMDFRDEAAAEKVLRNGMVLEKKIVWPKKKLPEPRLCFKCQKIGMKHRAAECTQEYNTCGHCGGCHRSNLCPRDTNQAVHCVNCDQRDHGPANQNCPRYIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4P6</accession>
    <name>A0A9P6E4P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H2, subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_113797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4P6"/>
    <dbReference type="OrthoDB" id="6222486at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204">
        <property type="entry name" value="OS02G0168900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204:SF1">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="418" mass="45522" checksum="4798C5886B2C2674" modified="2023-09-13" version="1">MKLWRFVYGHDGGPWNSGPNVTFGYVTWRVVTRFSFAHHAQDQMATDNVRLTIPVSDTEGSLVACKPNLMPFHIQYTGPASVRTFMLVEKLKFKGNDGSNSKLKETSNPKTTDSGVVEMKRETSKMDVDVDTPPVSVDVSEAISPEEDVDMAPVTLTRTNTEPIIVDSQPEITPSTSILTSMPSSSTLAVSAATSQTSISVGPSASSSSLVQAPLLEDLDKRVVSSFRGRTIHGLEVEVPAGYIGVVFKAEGGDSTQGAGTTEAAEEKVEKKRGRTRQDTTSSRAKASASTSSAKKDSAQDEDEEPTRLTRRRGRFTSSAVPMKGTVITIEDDDKPEETTDTPMVDLTNEDEAPAAEDSPTTKDDLPTRKITPQAQFASFTLWQADRVVDKTNDEYMKALTEWVGLASEIHRTDLDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5U8</accession>
    <name>A0A9P6E5U8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5U8"/>
    <dbReference type="OrthoDB" id="3069009at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="54668" checksum="99CBC004B4CA4744" modified="2023-09-13" version="1">MKKLTPGVEATTHRIEASRVVLNTLERTKVEEEIQFLNPAAENALGLLQFVRGIEEGEVDDDFAALALDSCGLVFVLISECDKLLNAGEEIPERFRWGSGELAEFLKEDVQVFVQKKIKRGFLSRRLRHVADDEKVVKHRERLAKWLVKLGIQPELSIHDAVDSIISEKVSRHDQDVQAARRAGKPLSQSRTPTPLSQLPSLNSTISIDKMHKPLPEIQVWQTTSTSPIAPADSSSSRSASLDIDNAKQKRLEAERLARKAEKEMWRKAEAEFNKLPVTPLRSSTPLTPLRAQDPSRPSHSRSVSIQEVSRPPSVASVLKPLRRDSDDLPAAPTSPPHDEAKDRELAAQLQSQLAKEVAEEDERKAHQIAASLQRQWEAEHERPRRSKKDRSRSRSRPSLRDPGESSSDESILTPERKKVLAWIKSNARHSPSPTGSPQTSRSGSPNPVQHRREYPPAPIGPVPLRRASLAFNSTQTPGNTAKPSAPLSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E638</accession>
    <name>A0A9P6E638_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E638"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7588" checksum="9B939F908C5397F4" modified="2023-09-13" version="1">MARKVYICSQTNQIDTQQAAMVEKSHPPIAACFGDESGTMVRAEQCFALLPNLSSWHLINHIHSILYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6X0</accession>
    <name>A0A9P6E6X0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6X0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="570" mass="63940" checksum="C417055E5D883C21" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7J2</accession>
    <name>A0A9P6E7J2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_198869</name>
        <name evidence="2" type="ORF">CPB83DRAFT_862027</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7J2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6594" checksum="543BC6860400ED52" modified="2023-09-13" version="1">MAGCARPYPYSHPHRKVKSHASAPQHRKCDRLLRSTLRLGSTFRLLGTSALVSTTSWGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8B2</accession>
    <name>A0A9P6E8B2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF35</name>
        <name evidence="9" type="ORF">CPB83DRAFT_909992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8B2"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="199"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="30506" checksum="DF3D0177D40C7DE2" modified="2023-09-13" version="1">MASSAPKTSWADEVDDDDLPKNEEFVDEKGIRTNIEYSINEEGKKVKITRKIKRTLQKSVVDHAVAERQKWAKFGAEKGSKPGPDRATTTVGENVALKLSAGNKQSEAEQAPEESMKSKVKAAGAGKVVCRLCQGDHFTAKCPYKDSLGSLEQPPEEPGPAVAPAASAGGKYVPPSMRAGAGRGAGESMRGAGNRDDLPTLRVTNISEDTQENDLRELFGVFGRVARVYVGRDRETGAGKGFAFVSFEERANAQKAMEKVHGRGYDNLILSVQWSQPRPDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8K5</accession>
    <name>A0A9P6E8K5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8K5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="185" mass="20919" checksum="BB45E0327B6BC3EC" modified="2023-09-13" version="1">MVNKRCGSPIEKSNAKVPKTDNQILEAALGRVTKQNLKRAPVTTLTSLCKNLHLSDDDTIKMATKHTLQQILTLHLKNVGILSLEDQQDYTLDERKLVRVRVFRDAGDFETTYMQEERVRLNSKGGLDVAMAAFQMGFTEGHLEPIDPLRFKRVFIQDSIISADLLPMLQGDQGFIRTVHTINNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E989</accession>
    <name>A0A9P6E989_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_576722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E989"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="120" mass="14062" checksum="8C013B8375618E5C" modified="2023-09-13" version="1">METGEKAYPCELCSYVGPTPYNYTRHKHINHSPWKDLELDMHEPGYKILVCPYGGCDFEDRTVRRMIIHMLDVDDDGLDLCPNAPEFREIKAQYDALVPQDPRTEALYIYIYNEHKPAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9E4</accession>
    <name>A0A9P6E9E4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_569923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9E4"/>
    <dbReference type="OrthoDB" id="19448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040276777" evidence="7">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="139"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="387" mass="39991" checksum="7C0FE1C2CE3818DF" modified="2023-09-13" version="1">MRFSAAFATLALFVLPIFAAPSGLIDIQTYRGEKTGKYIVKFKPGVSPKAWVQKLGLTNSVQWKNFNGLASTLSTDNLNTLRASADVQYITEDGIVHTTDTITQTDAPWGLSRLSSPGGLTVKDDTSLNYTYVYDSTAGAGVDIYVVDTGVYVNHTQFGGRATWGFAAAGYAQADGHGHGTHVSGTAAGSQFGVAKAANIIAVKVLSDGGSGSIAGVVSGLDWVRSQAPTTGRPSVVSMSLGGSANDALDEAVEALTAAGVHVAVAAGNNEDDAKWYSPARAPSAVTVGAFDVTDTYAWFSNYGPLVDISGPGVDVISSWIGSPDATNSISGTSMATPHISGLIAYLLSKDGSISPAEMTTKLQALSLKNVITEIPADTVNDLAQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9P0</accession>
    <name>A0A9P6E9P0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_772718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9P0"/>
    <dbReference type="OrthoDB" id="3214502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="12010" checksum="C807E4F222D4DF9D" modified="2023-09-13" version="1">MIMYNIACQYCIHLRARIGHLLPEGLEIDRAIGLFHVHGHKDQCFFRYSPSFIPKSGKVAGEILESLWSILNHIAPSTRTATLGHRAEILDDHTSDSNRKKGLGMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAG2</accession>
    <name>A0A9P6EAG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAG2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="497" mass="53408" checksum="754EFC765680FD25" modified="2023-09-13" version="1">MSTSRSPSRHSPTLSQSSVTSSRSDGTVNALRKKCPNKIKSDDEARILWVEAKNTRASYQRLKTDKLLELEIILQSIQQTEDALGDADHFIGELYYLIKRSGLKPPQMSDEVEDTSYTHTIQSDDDRFSLKLKPTTMTVLSKPVTDIPNAAGRRPAPNKSRTPQRQGGQLKAKLATSKENLPPAAPAASSMRPVRAGAGKNMAMLIQHEKSGSDEDLSARKRKRNPREPATVLSTLTSGVPTNATENPMAPPKKKLKHRASEGQAGIVAPSTFDSSLMGAPLPTNLEPSSGQFNLIHSMSSGSNTQGSANGAAPNMTAQMSPTHMQPVTSGLSQQSPLVPTPNTIASQYSSNCYSTPASFNVNEHQDLSTNGFYNQHSTALSFNMNNASSFEEQPHFDNFFDGLSNQDHSSGMAMPSFDLEQDALPVSGKTDLMLPPVNPGTFGEEDSETEDDENQAGDDADQAGNDEGQAGDDEGQAGDDEGQAAGDEYSETGVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB88</accession>
    <name>A0A9P6EB88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_795877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB88"/>
    <dbReference type="OrthoDB" id="441444at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="290" mass="32550" checksum="1FCE1AE5E4C78482" modified="2023-09-13" version="1">MFRTCLTSGSRLVFSSPSSSSFFHTSSTNLSHASKRMSARTKKKNIARTAERAKQADVDKPSVVLGTRPNEESEKWANCKLAKILVTEESLAASTEMNSRDFSIGKVELPKEFGFGVTEKEAEVLFEDLPIASQHMTTQVSQYAQDAPGKISPVPKKQMPTHGMVTEEAEREVMKANFLAKALDLRNANAAGIAFENRRRIIQAFSSPENSFDSGRTEVQVALLTYKIRNLWKHLLTFRRDVGNRRGLRDLIHQRAKHLKYLKKSHRARYDALLDELALDPSSVEGELVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBI9</accession>
    <name>A0A9P6EBI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBI9"/>
    <dbReference type="OrthoDB" id="3061877at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="580" mass="69174" checksum="1C71985B64305C64" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBN1</accession>
    <name>A0A9P6EBN1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_857830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBN1"/>
    <dbReference type="OrthoDB" id="5571754at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9526448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="15470" checksum="5460334F73A140F5" modified="2023-09-13" version="1">MADNSSPVTLRTRKFITNRLLARRQFVVDVLHPNRPNVSRVDLAEKLAALYKADKGRVVTFGLRTHFGGGRSTGFALIYDDEASQKKFEPKYRLIRSGLATKTDKTSRKLRKERKNRAKKLRGTKKSKAAEAPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECT1</accession>
    <name>A0A9P6ECT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_907875</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.140:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="17">
        <location>
            <begin position="243"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1553"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1598"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1559"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1605"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1680"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1735"/>
            <end position="1754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9527063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1754" mass="194688" checksum="43741C3B62E10478" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDH1</accession>
    <name>A0A9P6EDH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GroES-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDH1"/>
    <dbReference type="OrthoDB" id="3233595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="14"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="356" mass="38246" checksum="2CABFB624DEA9D22" modified="2023-09-13" version="1">MSQTQTQAALVIPEHLSPLKIIQIPIYTPDRGELLVKIHAAALNPADWKIQTEEYLECMDKFPVVIGLDRAGEVVQVGEGVQGFKKGDRIVTPSAFVRSRYQGFQQYAIADAAFTAKIPSNITYSQAATLPIALSTAFSGLFAEFPYGAGFPAPYSDEDRKTGAGKAILIIGGASSVGQFTIQCAKLAGFSTIITTASLTNASALKSQGATHVIDRSLDAESVISRISSIKPSDPVEVVFDAIGLKSTEKFGFEVLAHFKQNIFVTSDAAPSELAAARTSVKTSKIIAAPQMPWNSNLLSSLFHDKLYEWLEAGVIKPNRLEVLDGGLNAVYEGIKRLENNQVSGVKLVVNPQETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE33</accession>
    <name>A0A9P6EE33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE33"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="17404" checksum="B27861665F7B9AB5" modified="2023-09-13" version="1">MQHTSKAFSFASQLPKHHNLLPASRKVSVFKASTSLRQNLHSHSQCVIHTKSRQPLKLRSYSTTPNPDLKPNQNVFRAIDASLRELGLSGPAYWFIVGTFSLIALLESAFWAQLLYRKFWTKSEGEGETGVLKEWAGWWGGWLGFGKEKEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE81</accession>
    <name>A0A9P6EE81_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_855319</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990625">
        <property type="term" value="P:negative regulation of cytoplasmic translational initiation in response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016255">
        <property type="entry name" value="Gcn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000660">
        <property type="entry name" value="Ser/Thr_PK_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="16">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="229"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="560"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="629"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="727"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="141"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="630"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="731"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="802"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="566"/>
            <end position="574"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="589"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9527861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1591" mass="177531" checksum="0683D46816433438" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEB2</accession>
    <name>A0A9P6EEB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEB2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9552" checksum="D780DEB78CACB2E4" modified="2023-09-13" version="1">MYILVYLFAGPYGLGEIVSVLYDPTASLDKNGDPFPHIRGCLWLKLIHRTSTSNREEVTGGFCAVHDTVSGTKTILPQASRPTKLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFK3</accession>
    <name>A0A9P6EFK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="10">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="9">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_855162</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="9"/>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFK3"/>
    <dbReference type="OrthoDB" id="5322683at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07123">
        <property type="entry name" value="ALDH_F4-17_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000006">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000005">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="11">
        <location>
            <begin position="70"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="547" mass="59648" checksum="EEB4870A2EC983C1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG99</accession>
    <name>A0A9P6EG99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_835919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG99"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="35446" checksum="EA2F3162AA59C359" modified="2023-09-13" version="1">MSALPRGEISADRLSVLEQYKARMAGHIPTSVTTVQLNPSQLAWGSNPTPPISELTKVWKEQQTNMVLDEKQALDPADIWRARMAALRTQANDQQTQSSPNGTLDAGIGIIHSPSGKHDMESGRHDMVIDNVPQPSAQSSEQGKSIAIDSSHLRAAQIPAANNSDTFLERIFSLMSKRETLLKSCLNNLEDSQQRKSTESKFSDADLDSLYALIKAKTPYGSRQEILAKIRATEQEAAGVAESETVIVEGVGYCDSAHSAEPFIDTPYKLLSEPYYLRVTYYPICFEPSRDSQEDPSSADIFFIYTEDRRCGIGINIDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGG4</accession>
    <name>A0A9P6EGG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_835987</name>
        <name evidence="8" type="ORF">CPB83DRAFT_907008</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGG4"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041010914" description="Hydrophobin" evidence="7">
        <location>
            <begin position="20"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="119" mass="11582" checksum="A1BA226FCCDB5B38" modified="2023-09-13" version="1">MQFKLATLVSLTIASFAAATPLVARGGDGGSPPPTSQCNTGSVQCCNSVQSANSGAAAGLLALLGVVVQDVTAQVGITCSPISAVGIGGNSCSSQPVCCQNNNFNGVVAIGCTPVNVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGV0</accession>
    <name>A0A9P6EGV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_835660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGV0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="26945" checksum="8C5CAB084AB7CC5D" modified="2023-09-13" version="1">MFEYSTWAELITRHIYRCLRVYSLLVIGRVYLLHPGNTSQPSVHPPPPSTATSHALALFAFYDPRCRHARAQMDELNAFGFVGAKTRQGVVVLEFEFGGAERVGFGGVGYIRSIGQARTGVVPRFSEVQQPVLPYFPLALRLTGLRGVDESIGIPIRHIVHPMTSHPKAVASAFQVSTAMISIFIRTYSDYKQYTRSLSPIFFHPRPLDSDAMGRRARPQNDLIALPIRIFSQVEGSHPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHG5</accession>
    <name>A0A9P6EHG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_868907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHG5"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="962" mass="107655" checksum="3A6050B2CC02B46F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHQ6</accession>
    <name>A0A9P6EHQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_275413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHQ6"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="11"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="11"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="203"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="432"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="463" mass="49971" checksum="A2BBDF64A30B4ECE" modified="2023-09-13" version="1">MAAPEVSSVKPPRPPNSWILYRAFMMKKLQPKDSQERRLSQSEMSSLIASMWRNATADVKREFEEMAERLKLEHQAKYPGYKYQPRKKEEKDRAKEVQKQNRAAQKRDSRSKRGVSGSSSSMPPAPIQPMVNPYYNPHILGLASALSPPLSAAASPPSSDSLSSPLPLLMQSTPLPLASPRPSHPHSLSLLGSEALTASQLLMPPTNQQHPGTYLPSPSATPGPISTFLPSDASGSADTALTPQQDDAGLTWPGSSSEGHDQNSLLLNSNTLSFDVGNNWSDMMGSDIASFLSAPTPGMFQVQGLDMVDFGSNSGGELELSIPDIHVSQDVATFLRAAYDKDFDPSGSSMHTPMGSSFAVPDQFDFSALLNPYPLDSTDVAIHNMGFFDQHFSTHDNSNSYNDQLSPIEPSQPSLDVVSTLSPAHLHVPATSTTSTYVPPTGAAHSSSRRVGGNWSRPPFISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHT1</accession>
    <name>A0A9P6EHT1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_875363</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHT1"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="508"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="592"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="393"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="543"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="638"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="713"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="767"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="881"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="450"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="720"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="791"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="829"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="895"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9529913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="977" mass="104931" checksum="19DF41D454703732" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHT8</accession>
    <name>A0A9P6EHT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_811644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHT8"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="12372" checksum="90EB4E7327419AA6" modified="2023-09-13" version="1">MSMIKSVINVNGFAFCEEHGDEYCNLCTFDFRTGNNYYIMDEIPKVLRGALEDDRTFTFNAYRVGALHANTRKEEPEFKCRKHGTTDCEVCFDWAELVKKELLQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI03</accession>
    <name>A0A9P6EI03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_852974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI03"/>
    <dbReference type="OrthoDB" id="869189at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="12314" checksum="450C9E741E16D8FD" modified="2023-09-13" version="1">MSGAATTAATSKFTSFMNHPAGPRTVFFWAPLMKWALVVAGLKDLSRPAEKLSVGQNVALAATGFIWVRYSLVITPVNYSLAAVNFCVGLSGLTQLGRIANYRYSQPEATSPKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI83</accession>
    <name>A0A9P6EI83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_765637</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI83"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="247"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="413" mass="44970" checksum="CAA4EE65A73254E9" modified="2023-09-13" version="1">MLFTDLHTSPPPSRSVSRGLIRTASSSSLGCGPISPLPQTFPEVSAKHHLRPTRFSIDYSLPSSTESASARLLSCSVDNTLLFTRGNRVYSKNLNNTLNEDFIQLCKLPDSRGSLRAIECGGKSHPGVVAIGTSQGFIQTWDIRTRKMLMSWPTTKDISALAWNGSVLTVGGAKGTIRLYDTRISPAEKMREQARKITRHQGRISCLSWNDDGKLLASGDSSGMVHCWESGQIVPMNVGEFVQRRKKIQHDGSISALAWSSWSSKLLATGDDKGCLRLWNVNPNDPSSNLATPGKVDTSARITGIHFSTQCMEILTTHGNAVPIVDSAANNSPSHKSPFANSLAVHTASLRHVTTLNVPTDKPIGDSVLSANGMKVVFTVPDEAKINICDAWAKRKELRRQASFTSDTSLYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EII0</accession>
    <name>A0A9P6EII0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_256572</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EII0"/>
    <dbReference type="OrthoDB" id="10259236at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="94" mass="10906" checksum="250669987FCAC9DA" modified="2023-09-13" version="1">MTKGTSSFGKRRTKSHTLCRRCGNRSFHRQHKTCASCGYPSAKIRSYEWGLKAKRRKTTGTGRMRYLKEVSRRFKNGFRENTVAKKRVSTKSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIM7</accession>
    <name>A0A9P6EIM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ceramidase</fullName>
            <ecNumber evidence="1">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_764668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="1"/>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIM7"/>
    <dbReference type="OrthoDB" id="5273684at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029130">
        <property type="entry name" value="Acid_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583">
        <property type="entry name" value="ACID AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583:SF1">
        <property type="entry name" value="ACID CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15508">
        <property type="entry name" value="NAAA-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acid ceramidase N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="375" mass="42241" checksum="3B81F63D178CCF65" modified="2023-09-13" version="1">MSSSDSKSRPQVRIALTDQAIPLYRVDMSKPPGVRYEQICEDFKDRMAQLVLIYDDILLLSGFPRLAAFLARNLLKRVSSDEETAEIKGISHLTGVPLHLVVAYNTFLDLFAGCMSGGAQTKIPGSRGTRMLHFRNLDWGMDMLRNMIIRVEYVREGKVVARALTYAGYLGVLTGVRKGLSMSMNYRTQTQSKSWRASNTLHYVSILLGFRPSIASQLREILLDPQCPPSLNDLIDKFSKITASSSYLTFCSPTAVLVIEKDLKSSTNHYSEDFLAVANHDVSVEAWSSEKWKEYVDEKLDGEIGGIKDLLEDSIDRKNCVCRWWGDKGKGKVTLNDVKSWLRKYPIRNEMTHYSCIMDPSVEGGGLVWAETCQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ79</accession>
    <name>A0A9P6EJ79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_881946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ79"/>
    <dbReference type="OrthoDB" id="3155440at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="709" mass="80804" checksum="EE78DE50F0E6076D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ83</accession>
    <name>A0A9P6EJ83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_725609</name>
        <name evidence="2" type="ORF">CPB83DRAFT_737968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ83"/>
    <dbReference type="OrthoDB" id="2917041at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="59" mass="6264" checksum="08309D88A4DEBAF0" modified="2023-09-13" version="1" fragment="single">IKPGNIYGMDESGFPPSHQGVERVVGRRGTKTQHKTGSANRENVTVLVTICADGTALDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK59</accession>
    <name>A0A9P6EK59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_201350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK59"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="170" mass="20142" checksum="0CE237ED6075FC4B" modified="2023-09-13" version="1">MPIRSPQNPTLPITLGNICVTNNKTVHLIDPGGFRRFGFRRNKLEIRVSALSYYFTLLHDADSRRRPYYSERRTYLERMPFALSAWYYRPINQTLRKPWDLSANIVPVQGFNDQLLSAYNYFFMRPWFRKPPARNCFMAPNLFPEFCIEPRTLDCMLRASELCDHPLISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK75</accession>
    <name>A0A9P6EK75_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_919156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK75"/>
    <dbReference type="OrthoDB" id="3226575at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="48086" checksum="5E1AD84F9ADB5464" modified="2023-09-13" version="1">MSTIISQPVTVALGSISLSFRLKTFCRPPQNSRLDDLPMELVTEIFRHVVKSSPDPRLACRSAFIISTVNRLWRSYALGDPKLWSPICFMPPRRSQGSSAHLEQSTVCLQRAGEFGIDIRIIEVGDGEQDKEFREDEVIKVVAALSVKFDCIKHLRVQLKSPHIISTFLHALQAATTDRCLRQLQTLDLRCTRKMLSSFGSRSPVAPIRLLEATPSLKAWVIDGVHFDWPMLSSPHPLALSIPSCLTVIHLAGLSIHQWPTVMNFRQFLQPVSLTLRRLVLNGAGPAYVLSHLRQPATAFSSSIPLPGLISLELSGFTSDYAGYVFDLLDCPNLRNLTIRSFDIHDCESIVMALTGKAHRVEKLALYSQSSRSLQNSRTQLGSSEDALLTLATRKLLVAWLNSIPRLRLLVVDQGGIVALQALLKAEVIVLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK99</accession>
    <name>A0A9P6EK99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_892565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK99"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="91"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="539" mass="60034" checksum="E0D8D405A081DA9E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKE3</accession>
    <name>A0A9P6EKE3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_850142</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKE3"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000002">
        <property type="entry name" value="Guanine nucleotide-binding protein-like 3 (nucleolar)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="101"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="485"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="592" mass="64739" checksum="ECB9B1C4FE9CFC72" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKJ9</accession>
    <name>A0A9P6EKJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Importin alpha re-exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_164632</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKJ9"/>
    <dbReference type="OrthoDB" id="3268246at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="980" mass="108335" checksum="3D2E08A58397F82F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKN6</accession>
    <name>A0A9P6EKN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_152871</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKN6"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="15"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="669"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="938"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="669"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="705"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="729"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="955"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1005"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1024" mass="112885" checksum="A0ECB13952429A7A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKP0</accession>
    <name>A0A9P6EKP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_144250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKP0"/>
    <dbReference type="OrthoDB" id="2757368at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="44976" checksum="5285D325D2024BDB" modified="2023-09-13" version="1">MDQRFASPRTGGPSKEPSPAPQHSTHFRTPSSPRAEDMAYNKRLSISSRSSRSSSSTRVENCFTSPSSAKQRMPAPEPFTHPGHGDRRPPLPENLYHSPQSTRTSPLLSSPMQIHHEPTSTRSRPIQTPITHNFSPRTPPPTFSSPPLKRSRAEYEADNQRSAPTSEPPQSRARTDGIPPLRQHIAQPYNQRNSPRTLSPAQSGSAATFLVRHEDADAKPVVVKMEPRDDMDQEEGEVNDASSQLGRSRPSSSRSEPSAPPFASRLPTPPQSIPIINHRPPPSNPFNIPPPATQTESPITSRSQVPSISRPRISLVPRPTAGRTNTMEKPAEQPPTTPGGGKPTNSNFYHPQLQESRVDNNLQTRPQVTQPLTPQVPPQPPRPKQLGISHIDLLYKTENGSMVCRMCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKY0</accession>
    <name>A0A9P6EKY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKY0"/>
    <dbReference type="OrthoDB" id="3364905at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="485" mass="53270" checksum="31134E90ECD24522" modified="2023-09-13" version="1">MPHYASQEDAFSSNSHFLSPGIQGSRKAQNISTRKSSASLRPPPSMDLDDDDAGGAGRHHSLAHELAVALMPEPSVGSKLLAEEFGIEYDEGAEGIDEVPTHTLNQLNGTEFASSDQDVPSLASEIGTSASDASFHDLPPSESEDLSEHFKAHHMAPQDHSEFDDPVFSSPTAPKRRAQPKKPEQDAMEVLAQDLESTDKFLNHLRTIDSDATPSSSQQTRSVEKIASDMIRRMNDSVRERESQVRELLECEREFRKISGEVGGNEVLGMLDELTGTEELSDTHHPELSKASNRQLESVSEEPTPRHRRQYSQDWELDPDRQHLGDEEDEVYESAVSPSKASFPPPPPLVGPPTPANTVPQLAHLRTFTTSLVSHLTTLSEHAQVNGAATAEAGRKIRALKNKLGGWRTDWDSAERSRQRIEKWEAGIVEGDSSASTAFISSNTTSPGRITSKRVDGRLLVQEHLRAFEVALVDAAMKTQAIMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL18</accession>
    <name>A0A9P6EL18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL14m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_787084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL18"/>
    <dbReference type="OrthoDB" id="274765at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000005">
        <property type="entry name" value="50S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_uL14_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="133" mass="14361" checksum="1434754D88B5CD1F" modified="2023-09-13" version="1">MIGLKSTLNVIDNSGALIVECVNVLKNKVNNGWGSVGDEIVVVVQKARPVSAATQASVNAVKVRRGDVRRAVIVRTRKAVRRPDGSYVRFDDNAAILLNNKREMLGTRIGGMVSGDLRLKGWGKIVSLAPRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL23</accession>
    <name>A0A9P6EL23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_723862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL23"/>
    <dbReference type="OrthoDB" id="2999691at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="57" mass="6944" checksum="D3BB09ED65C0BE58" modified="2023-09-13" version="1" fragment="single">RIKNRAPAAIQITAEQLLREAQERQETAFRAPKQRVEDFEELNEYRGRKRKEFEERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL97</accession>
    <name>A0A9P6EL97_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_920498</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL97"/>
    <dbReference type="OrthoDB" id="653904at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017054">
        <property type="term" value="C:negative cofactor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22906">
        <property type="entry name" value="HFD_DRAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="5">
        <location>
            <begin position="9"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="99"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="26475" checksum="0370EF969EB3A6CE" modified="2023-09-13" version="1">MKNKNKQTKFPVARIKKIMQKDDEVGKVAQATPVVICMSILFYISALELFLALVIEKSSAVTTERGSRKVEVYHLKHAVETTETLDFLKELVQDIPDPSAGGTIDLEAEASEKKKRGAGKGKRAAAAAATAAGDSAADPDAPPPKRRRKKKADAAPGAAQGSSRNGTSKHKAVKVEISSSMDADPEEDDSPTTMGGGLRNGDHDDTEMKEDPDDYDDDDTMKPPPTSGGSSSYRLKSPVDDDDDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM17</accession>
    <name>A0A9P6EM17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_904838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM17"/>
    <dbReference type="OrthoDB" id="2746456at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="49"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="39557" checksum="2380C0005E333824" modified="2023-09-13" version="1">MDGASLPTPTSSRNLKREREDEDIDGVKERSSKLPTTCIKHQVHWALDGNLLLQFGDVRFKVHRSRLVSESPYFQELINASHGNPDDDYEYKEEIDLLVNSKKVIGGLDCYYFPQDCNDDLPNAEAFSVLLDAMNTGIDYVHTPPSFATIKALLNAANSLCVTRYVTFCTNFIKMEFPSEWRSIPETSSPMAIEGVLLGSRYLVLEKILPFTYYELARRPAGATSGGFQELNTLQLRKLINLQKHLSIQWDNIATTLEVDCSKGPPLKRQVCKTCHHPSLKLFLSARNAYPLDPILGTRRLLCTDWVTKKYCDSAAVEVQERLKTCASRIWAGLQGWLDEVKDEDETDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM26</accession>
    <name>A0A9P6EM26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_785224</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM26"/>
    <dbReference type="OrthoDB" id="10261385at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000003">
        <property type="entry name" value="Tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000033">
        <property type="entry name" value="tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9532301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="435" mass="49681" checksum="F53EA4838FB5F771" modified="2023-09-13" version="1">MDTQIIADKLPHSLAAVTLEASTKESTKANAQIVTPWDVQGSVSTDGKQQAIDYDKLVEQFGTRRIDDKLLERFEKLTGHRPHVFLRRGMFFSHREFDKILDRYEQGKPFFLYTGRGPSSDSMHLGHMVPFVFSKWLQEVFEVPIVIQLTDDEKFLFKHELKAEQTMAFSRQNAKDIIACGFKLERTFIFSDFDYVGGAFYQNVVRISRQIPYNQVKATFGFNESDNIGKIHFASIQAAPSFSTSFPQIFGTQKDIPCLIPCAIDQDPYFRLTRDIAPKLKYPKPALVHSKFFPALQGPQTKMSASDPNSSIFMTDKPAHIKNKINKHGFSGGRETEEEHRRLGGDTEVDVAYQYLTFFLDDDEELERIGKEYRAGTLLTGQMKGRCIEELQRFVADFQERRSKITEEDIDTFMDGSRKIDATFGKRKAGPDPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM32</accession>
    <name>A0A9P6EM32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_848918</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM32"/>
    <dbReference type="OrthoDB" id="10252587at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="58"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="8">
        <location>
            <begin position="150"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22961" checksum="BEF0AB7480792958" modified="2023-09-13" version="1">MSNETRQYGDLSNQLLMESRRSTQTDTLLKYNDSLVRTIIREQRDLEKAIEKLLINGQPPPPALLIIQTAINRNKRCLLAYHAHRVDRLRDMYWAVGGALPHILSDADIRGKLSPHEVDYLRQYNSSVMEFRSEFSHELDITASITSPPKDLHVLVRVVKECGVIQTELGTIDFQKGHRFMVRRADIEHLIVQGYLEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM63</accession>
    <name>A0A9P6EM63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_105946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM63"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="18583" checksum="D793E9D21268F26B" modified="2023-09-13" version="1">MPRKAAATSNEDAAEPRRSSRIKDQPKAEPVKKAPAKPRAKKAEKEAAVKEDKPKSARGTKRKAADEPNGADEGSEEPAAKKAKPASKAKPASSTKPVSKPASKAVKPASKASVKPASKASVKPASKVAKPASRAASAKPASRAGSKKPASKAEAPAPASTAAQVDTTIAEEPEAEAAAVEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMU7</accession>
    <name>A0A9P6EMU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMU7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="227" mass="24833" checksum="D85262510916F2B0" modified="2023-09-13" version="1">MIRSEMEKSSAFLSPERTTAAIESALRRRAQRTQSFSRSKPQGEAEISGQPRRLDSGGPRRLGPSQDSPYAQRRRPSQASKSKHGQTRKPPPKPTQTATTVQVDDVDLSIFEGAYAPTFIGAAQTYSDPQSLFGSAFSAKDATVIAETGKRFVVPTSRIDSFRESKYDAYIKAAPEDFGALPDEIGPLRVAQRTLSHQQHYSLPAKVGTLNLLARITPKTSTHTKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN28</accession>
    <name>A0A9P6EN28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_890458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN28"/>
    <dbReference type="OrthoDB" id="3065671at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="344"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="453"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="922" mass="103283" checksum="E4EBD9BA61E9BFDC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENI2</accession>
    <name>A0A9P6ENI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_847921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENI2"/>
    <dbReference type="OrthoDB" id="3229610at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF19">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="28"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="39363" checksum="2A2E93E9D135CB60" modified="2023-09-13" version="1" fragment="single">MTLQPPSLMVNRVIIGGFYSVASLTSVLRLIYRWKRQRLWWDDFWALMALLSYSFVAMVCLILPMQFLSQRSANVQVFRFLGVFLGTTLTLWAARLSLAVSIVRLVPDSSFRRFAKAIAVFFGILFLGLAIQKLFFCCGTQWKEIGVCKITDLTTYLSLATDAIGDCWLVGAPAYMLSNTKLSSHYRLLLLLIFSASIFVIFSSVVHYCFILTNQVSYVSIVAHIELGLAITVSNLLVLGTWLYRVVRRSIRHPPSPSEGDCAEKSRTSQSRQYGPARNLMDRLSNLPQTRFTLTTMNAEFEVPTSPCLFSTFEIPPSHPSHIRSGESEEPGLTLFHVKQTNQSAYPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPN8</accession>
    <name>A0A9P6EPN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_490184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPN8"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="372" mass="41648" checksum="CAC4AB7BA4C31C14" modified="2023-09-13" version="1">MDFNNASTKLGGVDYTHLRNPYAPEAWIPSELASVLRFQHYLAIGCITVYLWDMLQSLPDDYAVVFKRTFCLQTVVFLAIRISTFIFFLSTGFFLMTDLDNCIPWGIINSTAYIATHCSIALLFYFRVSAVYLHNRYIINFFRICWLGAVAGTITGPLGITYKHITLTRTCVVEISDSVQKARYPVGSALAQTFFDLLVCGFITYKLNLANRLGVANGGAGTTRIGLIARWRVTCGWLAWTQRTAMLGQRFMQDSQIYFLIIICVKIPEIVCFFAFAKSSKGSQAQLLLVFPDTVIVSILATKIYRQLKLGRPGLLDGGHQTEMTGAKRVLWFETGHFSRTDIGGSSGTRPPQNSPRLHGSSQLHSHLPVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQG8</accession>
    <name>A0A9P6EQG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF500-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_805866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQG8"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11525">
        <property type="entry name" value="SYLF_SH3YL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033643">
        <property type="entry name" value="SYLF_SH3YL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF7">
        <property type="entry name" value="YSC84 ACTIN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="1">
        <location>
            <begin position="121"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="275" mass="28341" checksum="6F8A785045FEE1A0" modified="2023-09-13" version="1">MSMLDKFRKGAQKAGVQATAFMQTSGGKIASGSRDFVQTFSLPGEAEKAAKILHSFLADPDHPESALNAIPKAVLQRARGLAIFQVVKAGFVFSGKAGSGLVIARLPDGSWSAPSTIATGGVGWGLQIGADITDFVIVLNSEDAVSAFSLGGNVTIGGNIAATAGPIGTGGSVQATLAHPAPMFSYSKSKGLFAGLSLEGTVLIERKDANRDFYGSPIPAKDILGGRVPPPEVASRLYEIIEAAEGLDETGLPESAYVPSATGQHDNTVFDADQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQV0</accession>
    <name>A0A9P6EQV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UBC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_866895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQV0"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000086">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="9"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="303" mass="32967" checksum="6F8D28C3B935CED9" modified="2023-09-13" version="1">MPALNKNNSAVKRIMQEAKELANDPCTDYTAAPLEEWHCTLRGSPGTEFEGGLYHFRILLPAEYPFRPPAIMVLTPNGRFELNTKICISFTSYHEELWQPAWGVRTAIIGLQGFFPLKGQAAVGVGSIEYPASERKRLAALSREWTCPHCQRSNVEILPDPVAPISKVEKPESSDAAQPMGTEPLSSGSTNSDATSAPETEVKPAFSSSSTSTPSDPPQITLTELPPRPSTYGSRIDHGQTALAPSVPVRLNAATSARSETSSTPVFTRNQNPTRSQKPPVLLDTTICILLVLLFAIICRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES14</accession>
    <name>A0A9P6ES14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_844564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES14"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="543" mass="58946" checksum="31B2942F602F0F34" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES71</accession>
    <name>A0A9P6ES71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_725519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES71"/>
    <dbReference type="OrthoDB" id="3269297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="27660" checksum="942871180FBCBB3F" modified="2023-09-13" version="1" fragment="single">PSSSSRRVRDEDINPTLCTPTKRRRFLHNALSSTSSGSFLVSSSPYKADTAILDPILELPPSRIPQPNWSLAQTPEKGWRSRETLEHDNTLLREALEQSRSQVNAQGVVIERTHAQLVYQNMHLRRQNFALNAKENQKKADRTQLFDGEGQIFSSDNFIHKIDAIAAATQATAAEKSQRANERRSRKAANEELEREWTRIKEQHELDVKAWEDECDVYANNDIPKREWPKKPVRPLKPKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESI0</accession>
    <name>A0A9P6ESI0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">TFIIF medium subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">TFIIF-beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_845005</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESI0"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000035">
        <property type="entry name" value="General transcription factor IIF subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="12">
        <location>
            <begin position="37"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="11">
        <location>
            <begin position="256"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="323"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00081473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="361" mass="40792" checksum="0A4B0CC7EF6901DF" modified="2023-09-13" version="1">MEEVMEEDKKPFEGENAQEDDSQPDPDEHLMLDQGNGKVWLVKIPKFLLERWTAVNVEDVHLATIRVYNPPKDGNGQPDGKTRIVLFLPPNRDPNNPDEPPRVQRSDWPAFEHTTTYAATGPEPDCYELDMVNDNVENQIVVAERPKDTSLSISTTSAASTASTRARTTILTGRIKHECNLRPALSRSYRKQMKERVRKSNTPLRQIRMIEDAGVAGGRGGINRLSSGVGVGAGSAFSDLVKAKQRPPKGAFERMARMPRNQLLDLLFTHFQEQPRWSIRPLREKTQQPEAYLKETLSQIAFLHKSGEFNGYWELQENYKTAGIKAENVPGPSTPGDMKMDEDDDEDEDEEDDDDDMEEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET91</accession>
    <name>A0A9P6ET91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET91"/>
    <dbReference type="OrthoDB" id="3005035at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="42918" checksum="FB01AAA0447C8D3D" modified="2023-09-13" version="1">MSFNNASFLVAIGSDSSNPTTMAQHGRHPRRRVTSDPCLPERLPTSGFIQREAESLAPQELTKQLIKTSMEEQADSEPTVELEEPPVPEARPRTLSSPRSAAYVRSFVKSLIGSTGRREPANGWTNVQPFEVMKAVEDRDLMFLMEVRDKAFSLLLQSSGGETPLVHAIRIGNKDVAIVLLGAFSRWVNRLEDEDIQKPKTQSLLKALRVGLKLAINEGLAKSQSDLIASFMQTLIMSEGDKWVFAQVSTIARALNAGSDGKPVQAAGEAVRKFATKELGKADLIASLEDYIANATADLLVLGAWSNVLQVVKVDLIPSSYFARDDRVYKNFVEKLDRSKPDIQRRCNRRLRWQLSILKEGLEGRTETFRRKVELLSQQLDEGDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETP7</accession>
    <name>A0A9P6ETP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_228172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETP7"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="557" mass="61649" checksum="D4360881645CF269" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUD1</accession>
    <name>A0A9P6EUD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_831127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUD1"/>
    <dbReference type="OrthoDB" id="3001771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="55148" checksum="6C97985209CF53F8" modified="2023-09-13" version="1">MAALRDLPSELLGSVFEELYLLNRRVKEPDSSEMVWEFLDFRNPNLFPWVLSRICQQWAQVVAQYPHFWTRVALDISSKEPLPLGAFRWSKNHSFQALVYHSGYSKELTPSIHADEYALAYTSVERNRAHTIKEALAPHLGRCTSLEYDVLLASSLPDLPNLLQRNSMPNIQVLKLDSRTFDSRLLTVLGTRSSFKGLSLTPFRCMEAFKLPMATFISIGRLDPQLWSHSKRDRFFRLQLYHYEFCITEQEAEYQNGVASISEFLRFLPSLHVPDLQLEDLSVCPNPDSATSPTSVITTDKTTPPPINLRLIWFTIKNSSKTFLDEFFQRCLIKADFTKIENCVLPNDATVYHTDDLTLIKMPSSADLSSILTHFSGDTVRFKSCLYLNDAYLRLLSDISCEMFQYLYIKDCEGYTIQGLKNMVITMEENWEEAEADTERDGWEVVTRMATINLKGTGPKPSSEDATWFREHLETFRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV32</accession>
    <name>A0A9P6EV32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Glycosyltransferase family 31 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_13074</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV32"/>
    <dbReference type="OrthoDB" id="2139606at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051072">
        <property type="term" value="P:4,6-pyruvylated galactose residue biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF333">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 31 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="633"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="53"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="638"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9535452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="825" mass="92964" checksum="67217FBAC0501B6B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JII6</accession>
    <name>A0A9P6JII6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JII6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8402" checksum="019F48C73E81F2CE" modified="2023-09-13" version="1">MVRSSPCFFLSRAKQKSILLTNLIFAQTMRFLAPQSRALSKRTPTLAKSCPVLTSNQDCLLRRTRRVASMCLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJF2</accession>
    <name>A0A9P6JJF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_863989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJF2"/>
    <dbReference type="OrthoDB" id="3049493at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="11261" checksum="2D5724E823F9D451" modified="2023-09-13" version="1">MEINIHRQLQHPNTVHLQDTFEDSKNIYILLQLCSLGSLKDLLDHRGCFNEPEVRSWFVQLAGAVHYLHDHQLVHRDIKPGNMLLDCDMNLKLGDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK72</accession>
    <name>A0A9P6JK72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 39B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_775027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK72"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="672" mass="75139" checksum="7865F30D9510EE87" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKM2</accession>
    <name>A0A9P6JKM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2264 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_773953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKM2"/>
    <dbReference type="OrthoDB" id="5150166at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049237">
        <property type="entry name" value="DUF2264_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049349">
        <property type="entry name" value="DUF2264_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339:SF4">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20938">
        <property type="entry name" value="DUF2264_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014753">
        <property type="entry name" value="UCP014753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2264" evidence="1">
        <location>
            <begin position="17"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2264" evidence="2">
        <location>
            <begin position="374"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="71146" checksum="812F1244AB80EE10" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLL8</accession>
    <name>A0A9P6JLL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="7">5.5.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Myo-inositol 1-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_909515</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="7"/>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLL8"/>
    <dbReference type="OrthoDB" id="2887at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000334">
        <property type="entry name" value="Inositol-3-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000069">
        <property type="entry name" value="Inositol-3-phosphate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000055">
        <property type="entry name" value="Putative myo-inositol-1-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="18">
        <location>
            <begin position="340"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00070063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9524988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="555" mass="60976" checksum="420300F42DF92653" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM31</accession>
    <name>A0A9P6JM31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_517449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM31"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="359" mass="39808" checksum="36D13FE923EE76D2" modified="2023-09-13" version="1">MSNDDTSGLTPFLNPTTPLAFMSKKDGDLLTLSRHFAFGSLSILCWDVMDSMVLDYGLFFVQKPSWTSIIFVISRLSALGFLGLSALNLTTAPLDCAVVVHSMNVAAIVSRACTGFLFYTRVKSLYSSKRLVLGLLAAALLASIAGATFGLWTLTGIRVGVPTGAPVSKYRGVCVSHTTIPYWSISLTPVTEAIFDIFVCIAITYKIQQYQESDDTSRCQTRGWERSNNWRNWVYRSKGRPLSRLADRFMRDSQIYVILALCIKIPEICLVLVAPLFFRSTSGISLMFAFPDVALTNILTTKIYRNMKLGRRGLTLSPFNANTTLDPTFIGLSVQNTSRIKFVKRPLALEVFTPSAREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JML2</accession>
    <name>A0A9P6JML2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_507843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JML2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040281225" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="11022" checksum="64C54BAF5FCBBCD0" modified="2023-09-13" version="1">MSIGWVLIDLFMWYGCLTRGSGKVRCVGIMLEIRDIFRQRSIFVSWVFRSSLWYELSYLKRWASLGLVNRCVHDGPVRILGNRPASVKNLTRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMS8</accession>
    <name>A0A9P6JMS8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_454137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMS8"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040189182" description="HCP-like protein" evidence="4">
        <location>
            <begin position="29"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="912"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="813"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="855"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="941"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="813"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="875"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="978" mass="108336" checksum="5640F6FE7DA4DA86" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN15</accession>
    <name>A0A9P6JN15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_857309</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN15"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040540923" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="176"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="690" mass="74228" checksum="A106F677F5B69FA7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN81</accession>
    <name>A0A9P6JN81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_837029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN81"/>
    <dbReference type="OrthoDB" id="3145912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="29060" checksum="EAA704595F49B183" modified="2023-09-13" version="1">METLLPPELEREIFELCATQYSSSAKSLILVAKRVHLCHPLLLEYAKQGVVTSRLRTGTTCQFVTNILSLCTNVRAVDIWLMEGDHRVLQGIVPIVGAPISRLSINTSFLFETVESKIRVNPSVLRHITHLDAIAVSEEIWMEEWRNLGLLPKLSHLAFSLNDNMRKHIVESILADPVGFRTLKLLVSFGHPSNENSLVMNDKRLITVSAPTEPIEDWIQGAITGHDMWDKAEKIQKRQELASSSLIPIEDLNLVEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNA1</accession>
    <name>A0A9P6JNA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNA1"/>
    <dbReference type="OrthoDB" id="2593747at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="42787" checksum="7AAF83635F7193DC" modified="2023-09-13" version="1">MSTIRIHGDGAADGRNSLYFLDFVQFRVQEELFRVPTIGFTIANPDFFYNLGTYSQQSNRELHDEVLELKKVSRAEFEGLLLVMYPFARTAQTYDEWLGALHLATLWDFADIRDKAISFISTTQEFKSMTPIDLVRFAKEYKVAVWLRDAYTQLVLGQSIDVDELRSSSRSKPLDWETISRLLQAQSLVNGSTSQVSPTAEKKSRESCEGCVNQADRSHCKTGYSPTYRCAVHPPAGAFINRVFRQEFVELGSELLVETPAAGERLATIGTSNDKFPDSAQTGPPAFHNDEAVFIASAILANSVIPCKMVNRTLKRCVYFSLNDKKRSAHGGRVDILPYSSQTFEWVKASHGRIPADRKPVEGGYEEDGRLLYHAAGVMIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNR6</accession>
    <name>A0A9P6JNR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose receptor Git3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_895778</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNR6"/>
    <dbReference type="OrthoDB" id="100006at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9526925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="43728" checksum="657A11523A5F52EB" modified="2023-09-13" version="1">MPSGVIFNFSERVGLLFSIESGIASILASTFVLSFALFKWLKRTVNSWGRGNLMRSDASDSGLFLNLMFADLIQACGWLPNIKWMVDATITDGHLCTAQAVLKQVGLVGTCLTSLAIALHTFGVLVLRWKPSRHLNKAIILCVWVVTALIVIIPAATPRNEPLYGPAGFWCFITPRWKTLQLTGMYLWIWIAAFSMLILYSIMFGVMRGWLNIGGSPNGEAPVDSEEDKQAKAIAKMMLFFPAVYIFTILPNSLARWLTTAGHDIPSEFILFGNTVFGSSGFLNFILFLLTRPAIVIGETITVEHVPNLPLHSPSISKHSYSDTSHMGQLPDFSQGEQREQRQSSHLSDGDVHQPSPTAESPFMYHLAATGRPYGRSKGAQLALEDDDESYGRLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNW2</accession>
    <name>A0A9P6JNW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNW2"/>
    <dbReference type="OrthoDB" id="2989516at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="544" mass="60977" checksum="F845957CE7794E5F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS02</accession>
    <name>A0A9P6JS02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pleckstrin homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_763367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS02"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13246">
        <property type="entry name" value="PH_Scd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033511">
        <property type="entry name" value="Cdc24/Scd1_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="653"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1158" mass="127503" checksum="69750418564BDC1F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS03</accession>
    <name>A0A9P6JS03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_763940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS03"/>
    <dbReference type="OrthoDB" id="340227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="3">
        <location>
            <begin position="49"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="25497" checksum="3CFC34B36ABB7D22" modified="2023-09-13" version="1">MGHSSSIGHADVLSPPLPVVLLSVPGATQRPPQPPHLKPPVPVPMSTISFPLDSTRYYLLGQLEYYLSPQNLAQDFYLRQNMDERGWIPIPLIASFNRVTQLTMDVQLVKDVLTLSSIVQVRGNMVRMGGWEQYVLPDAKPSNVEEQPLPYSYQNLTPYYDGMVGLAGMPGNGIEEYPPGYRMPSLADPTSFPPTSGGISKMAENDEEEDEVEFVMGEVGTWSGGSPDRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSL4</accession>
    <name>A0A9P6JSL4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSL4"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328">
        <property type="entry name" value="ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="239" mass="27667" checksum="8FB3F5FC395C5D10" modified="2023-09-13" version="1">MNLKPPQPLQFHPNTNEPFLRLRNHKNVILTPYRLDDTTGLVRILNDPLVYKWLYSTKFPFTLEDAKTWLDQTLSKSDAMLAELADGPDYISGTPLTAIREIQEDGTDILIGNITLARFTHGEIFNTETVDWENADENIAENLKLETGNPNIIWTIGDYLASTHHGRGIMSDAIQTIVYDWGVPKMNVRRMMIGAMVDNPASIKVFAKNDFKFWRRITDFDYSPYWGRMRDVEFHEWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSQ6</accession>
    <name>A0A9P6JSQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_850038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSQ6"/>
    <dbReference type="OrthoDB" id="3251489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="54056" checksum="2CCF19238275C80A" modified="2023-09-13" version="1">MVFYLPKPDSSIVRLFSYPRKRPTLEPPQLLSETDSQIYPSVSPFDRLPIELQVEIFSHCFPPFPRFDVNEGPLLIGRVCSAWRTVLLSTPRFWSSFEIEVNGSGPSVSLRDIQIVSTMELWLRRSRTNPLNVRVIHIPVGRIPDPLSAQLVALLIPEARRWRHVQFIIPTANMASLRHSFPNEFPSLRSLTLQMKGLWTSEPTFTLSTAGIPWAQLTRLDLQLEQNNLPDLNDCLNILRQMDQVKECTLSANCTLNSDQGIEVNATYLESFHLLVHNGAESAADSLAHFLCLLSTPSLHSLDLKWHVNNATNWSTAHQDFTTFLRGISSTLRTLELSYLPVSEEDLLDCLSHIPFLEDLELRFSLNDDEQEPITSTFAAALTISPPNAVEMTNTDISPDAQLLPCLTSFMLECNGSRLSFTALVAMINSRHDYSDSSSPLLRRVHVRSMKPVIREIDWQVALWAGEGMDISIDTVPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSV3</accession>
    <name>A0A9P6JSV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HCP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_759740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSV3"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF3">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="499" mass="54349" checksum="C3344229BB51B1A7" modified="2023-09-13" version="1">MSPHPPQQYQGWQGQQYQQGPPANSGYHNPLYNVASDVLGMGPPSGGPSMSRSMGPGGGPPMSSASSIYAGSVSSGHSGNSGNVSFNSSTDPYAAPSQIDNRPNYQRAGTSASLTPSSTKSKAVDLTAPPYTKEYIDQYRQRIKADPDPEAHFLYAKYLIDAAKHIRSAHREQKAAKKYTEVLVGESLKVIRRLATQGDAYDEAQFFLANCYGTGALGLQVDHERAYHLYLQAAKQNHAAASYRVAVCNEIGAGTKKEPARAAAFYRKAASLGDTPGMYKLGMILLHGLNGEAKNPREAISWLKRASEQADEENPHSVHELALLYENPSGQLVPYDPAYARSLLTQAGQLGYTPSQYKLGQCFEYGNLTCPVDPKRSIAWYTKAAEKGDSEAELALSGWYLTGSEGILKQSDSEAYLWARRAANKGLSKAEYAVGYYAEVGIGIKQDIEFAKKWYMRAAAQGNKRAMNRLTEMKRMGAAKRGNIARPTRQQDGDDCIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT73</accession>
    <name>A0A9P6JT73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_582251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT73"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8310" checksum="28BADDE54E781700" modified="2023-09-13" version="1">MELELACLSSWNTLDFAQHYEAFSTSWALELLAYQAVLSSFLCLLLPGLIFLMEDLPLLQERRLLALASNVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTB1</accession>
    <name>A0A9P6JTB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_786304</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTB1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="186"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="513"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="974" mass="111009" checksum="44BD51CAB722CA0E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTG1</accession>
    <name>A0A9P6JTG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_903077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTG1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="169" mass="17759" checksum="75FAB9F8D1014065" modified="2023-09-13" version="1">MPSLDITPELLNVLKLLTSSPQGQALHAQGYNTTAAESKATSPSPSASPTSSTGNRTPNLIDEAFEKAEFMRDVLIDHNLLNGVGHTPEELSRIHTVDRSCKGAKFGEGVRFRSNIGNFCLNPIELPAFPSADPVAPSVAALPSATLAAAAEERVSPALAAAKARRRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTU4</accession>
    <name>A0A9P6JTU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTU4"/>
    <dbReference type="OrthoDB" id="3188789at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="43471" checksum="147B99979CE54C4D" modified="2023-09-13" version="1">MSFQRSYSDATLNNVKNVESNTEDLNMQTTSNNLVTRNAFLIFRLVFLALLTNLAFLSIIFASWNVHAAVLAGFSTPTTSVFVVLQCCLVFICVVIAILSFFYPGTGLSRIIVECVWVGGLSMLAMGSAISASMNGFAVACQAAEMNICASASLLMPLTWLSSVLTSSYFMALFVTSIAHRSIYPDIWKRSVYEIEWFGQPVRLPSKGKVVEKFLQKDLESDSYVDLYGDIEGTADRRRRFIRESIVTDVSAPWAAQSVRRGVDLPFSRKPAGSDLSSSSSKRSTPILPALATAPPLSVPHRSATTAAMSTKSGSRFIERFRESTILTRQETPSQYVERFYAIQEDDASFPKAVVDMDQPIPLPRLSEWVRADGQKIPGTMTSHGPTGSRSKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU11</accession>
    <name>A0A9P6JU11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Fructose-1,6-bisphosphatase</fullName>
            <ecNumber evidence="6">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Fructose-1,6-bisphosphatase, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_867331</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="12">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="6"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU11"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000008">
        <property type="entry name" value="Fructose-1,6-bisphosphatase, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006779">
        <property type="entry name" value="PRK09293.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="17">
        <location>
            <begin position="11"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="18">
        <location>
            <begin position="204"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00070480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9532981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="36565" checksum="F79E2D832AD15C9C" modified="2023-09-13" version="1">MAEEVPSTDIITLTRHVLNDQLRLGSAATGDLTLLLTAIQVTSKFIATNVRKARLINLIGMAGETNVQGEDQKKLDVLSNDIMVNALRASGKTAVLVSEELEDAIIIEEKQRGKYCVVFDPLDGSSNIDAGVNIGTIFGIYRVQGDSTGSVEDVLRPGSEMVAAGYTMYGSSANLVMSTGSGVNGYTLDASLGEFILTHPNITIPKRGKIYSFNEGNSMYFHPPVVNYLKSIKYPSPPKTPYSARYIGSMVADVHRTLLYGGIFGYPDDKKSKSGKLRLLYEAFPMAFLTEQAGGVATTGTKRILDILPTQIHERCPVFLGSKDDVNDLLKFYSDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUJ3</accession>
    <name>A0A9P6JUJ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUJ3"/>
    <dbReference type="OrthoDB" id="3038309at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="78"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="751" mass="85870" checksum="92C1F07E38412210" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUR1</accession>
    <name>A0A9P6JUR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_805916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUR1"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="415" mass="47208" checksum="D6669A6F50839874" modified="2023-09-13" version="1">MLLSVESIVDTALSEKNDDWEVENDLRNPVIDSSEFAYRATNLVQIQDEGVKLAAKHIHQRMLVESYTPRTWRTHPLHICPSEPYDSADPLNTTVLNWIFLISSLNFSFWSEKAGQPECYGVNWRTSWTSRQTEVHTGYWALVAALDRALDEEIPITDANFYSSETLCPDSLIQHVFREADQCDESIPLFEDRVSIMRENGFILCNSFGGSFKGFVDEFHRRFSGQGTALDLVKMVTDTFPLFRDEIFYEGRKVAIWKRAQILVAEIWAAFYPASPDVPHPIFPGLKGPEIHRLTMFADYRVPQILHHLRIISYPQSLLDLLHSGSPLASGSREEVSLRCSSIIAVEHVKEEILRLVDEEGGDSAAALKSGTVCSVLIDFYLWDLAKKIELGEEKVDGIDTAQLVPVHRTRSIWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUT8</accession>
    <name>A0A9P6JUT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUT8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="59" mass="6597" checksum="81355DD9D3045B7E" modified="2023-09-13" version="1">MTTDRIPAPESVPNIKPPPRQLPDHKPPIPIKFSLQAKLPSVSQNKDGTLVHVRQKHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUU3</accession>
    <name>A0A9P6JUU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUU3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="234" mass="26956" checksum="18C014436C5F78C1" modified="2023-09-13" version="1">MAMRWDLTWTNFRLFSFLFVMPTFGVEKLYSYNIPSSPLLGPLRFLFIFLWLCGGRGREVVCSTMSRFLHPMRKRRERSSFPGSRRSALLLSRNLVSNPYLVLKPSAINTFIFVYATSILVIPTRRNLIDLTSIPMKFYPRHQLNRQNPGQSLTSYYHISTLLFFKYLSHLGSSSSSSIILQFSPSWPSSCCLPQGRDPYLVNISCAISALHDCRPRYLLSRPILTDLTCFGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUX2</accession>
    <name>A0A9P6JUX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vps5 C terminal like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_780598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUX2"/>
    <dbReference type="OrthoDB" id="9976382at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030905">
        <property type="term" value="C:retromer, tubulation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07596">
        <property type="entry name" value="BAR_SNX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06891">
        <property type="entry name" value="PX_Vps17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053055">
        <property type="entry name" value="VPS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037907">
        <property type="entry name" value="Vps17_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="88"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="572"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="613"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="713" mass="77898" checksum="E110D7B025C4543E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV10</accession>
    <name>A0A9P6JV10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV10"/>
    <dbReference type="OrthoDB" id="3014077at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="95"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="698" mass="79187" checksum="F12D36EB205571B8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWA1</accession>
    <name>A0A9P6JWA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_7260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWA1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6887" checksum="B7444444ADC1EC56" modified="2023-09-13" version="1">MTSSLMSYDVTMPYIPVDSLSDVVYRLVVDHTDPPPDYQLGFWATLPLTQTFRSQHNLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWM7</accession>
    <name>A0A9P6JWM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWM7"/>
    <dbReference type="OrthoDB" id="3153758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="317" mass="35366" checksum="A4F327E9265C66CF" modified="2023-09-13" version="1">MASNSTAKRAASTAPSLNSQLPYSFLGSNSSHSHDNGTGGRTYHIPNYATRYEKRSTQRTRQTISSYANDRTNLISVTFDEDRGSQRITIIFILAILFITAVPTWMGVPSLSQHYGPFKTTERHSGESNGSSDLDSPLDHARTIDVQQSQVNKHQLQSQDKTSWNVTWSKPEVSQTCHGFGTRQYTANLVNLPFFASWEDACRNTPVVIGGATYIHPSACEKGWLFGRVKGRWIVKSEDEVCLPHWGTPKDKGCSSAGSQRRHFEARLLRLKDGENRMALCWTTPIFIHGRPVPKPASCREGIWGVYGVWDVEDAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3T5</accession>
    <name>A0A9P6E3T5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157969">
        <property type="protein sequence ID" value="KAF9521982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3T5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="243" mass="26448" checksum="23F9C6D92EBB2F20" modified="2023-09-13" version="1">MPSRAARFTCFCAWCMKNSPLGQDGEPMGGSILEANRTAHRLRAQREMALRTPASGEVSNEQTDLSNAVLIETLTADYQNLKSSLPNTSTSAVLDSVLQGMQRLLVIGTGPSLSSAPLQNITNTPPNPTTSQFPETNVPIANNGPSHQQKPVAKREKSTHTKKAHKVLNGIEICAQSCLKRLGNLSVLSSPTELVDLETEYNLLHSTFNSVKQNVPSVDKRRKALRKMLLDVSTKLETSSGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E437</accession>
    <name>A0A9P6E437_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157957">
        <property type="protein sequence ID" value="KAF9522186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E437"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="222" mass="24956" checksum="C728B23100D09BB8" modified="2023-09-13" version="1">MSDSTSLYTHLALAPQVTAYLRSIQRDPAEMAIGELVAFLEGPEDSSTVSNVDVSEIGDDSESSDESSVVEKLGKMNGDSNPGSDVELDDSHFMSAGADDTEERRISEEFSVYQAVSSLYEKDVRNAINLKLILDEAQSRLRICASLLQIVNNPTFPQRRENRALIRLIHRLRKDLAKAEAYYDDEIHPRVRRDAEVNFKINDLLAFMNHGRRAAPTWEVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4F5</accession>
    <name>A0A9P6E4F5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_822892</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4F5"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9522383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="59301" checksum="BB8AA44006D917DD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4P5</accession>
    <name>A0A9P6E4P5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_112227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157945">
        <property type="protein sequence ID" value="KAF9522462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4P5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="305"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="426" mass="48488" checksum="2B261E9A9A8B98D2" modified="2023-09-13" version="1">MNVLIDFLLYTVTYHPSNIYQTQHHPQPQPAVIPHQGYTCQVPPPHADYGSLWRPQQFGYSDTISSTSALSSSYGSNPIESGSYYQGRPSSRPYTPSRDHNPQSTYTRSRSDSTHSRHMASHSNSYYDPHPSAISPTPSVDPRSFPPRGSSHLRPPSWYQNEQDSFQGHRGYYNTQGDGFASTSSARDMSGSHLHHLQSRPQSSLSTHSRSRERSRSRNDTSRTTYPSRSSTTSPSTPFKLSDVLNARMKEYPSIDWALWDPMTQVNFFVGPGRYGNHDPIYRSIAFTGTVPVAESVYIEAAPGRLDSLYIAITRWGPIKVSPREQKALTICDIIEGIDDWMKIPLHPRDWGGFDKTFMNQIFASYERRKRHSTPIHPLPENPMEGARRVDTLFCQVIWDGLELAQDFSHTKRLYLRLKAFHHVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4Z0</accession>
    <name>A0A9P6E4Z0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HMG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_733749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157942">
        <property type="protein sequence ID" value="KAF9522519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4Z0"/>
    <dbReference type="OrthoDB" id="5598737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040648">
        <property type="entry name" value="HMGXB3_CxC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305:SF1">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18717">
        <property type="entry name" value="CxC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG" evidence="1">
        <location>
            <begin position="216"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="785" mass="87921" checksum="368D4075B76F594D" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5P5</accession>
    <name>A0A9P6E5P5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_776091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5P5"/>
    <dbReference type="OrthoDB" id="3236755at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="26937" checksum="DFB01CE2B752C6F6" modified="2023-09-13" version="1" fragment="single">SKIIDTIGRQRMAAVVSDSTGNTRSHRKKLVIEIPTIQDLPDIVHFLSRMIGDIVKLPFFKEPILVVRAVIMKLNKSHGGKWDLDEAKKAFGIGRGLEAIGKTRFGTIIFASASVQRNLPAIKHVVRQGRVDFGDHASCFSTHVTRKSSAFEISLRQLVAVGTPAVKALTCLESNEATAGDVYIFWHAVMRATKEVIEDPSNEFPSEVQEQILGILNARHSQVFADGNLSTSADLYLAGAYLNPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6S6</accession>
    <name>A0A9P6E6S6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_839682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157917">
        <property type="protein sequence ID" value="KAF9523438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6S6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="33622" checksum="6AE88D1E7B6CD7F9" modified="2023-09-13" version="1">MWLCVTLLCQRLPTITHWRLVSLITPPNIVSSPGPTSLDIHNLPNIIEGRPLCAHLLRQSTLHWAVQRVFYSLQNFRSTDELSEFAKSSLLIMVLCFCESHNCKGKSVKERTFQDHKNEDYRLRINRAIDAAKRAKEAQDKRMTTLISNLSLGSSDNISTPAVLFAHSEDHVVLPVPTFVPEVPTQSIRSNSTTDTLSHIQSDLWALTSHTKPQLQSLPKPLKKSDPFPLASALEDARELQARATRVSASGSTAIALKSQLRTELNTLLHQLDLAQVSWRQQIDRFMEPQSLILQYSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6W9</accession>
    <name>A0A9P6E6W9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_688947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6W9"/>
    <dbReference type="OrthoDB" id="3270497at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="712" mass="77978" checksum="7B4744D13069A781" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E722</accession>
    <name>A0A9P6E722_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E722"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="13624" checksum="E0579BD3B137A3C2" modified="2023-09-13" version="1">MFKIASWALLGAEIRFAFEEKLNSVLSSINRVRRLYPRVEISLHLPAAKTEYNPATMEAIDVDGQVLKNVPKGGQKIATALGFGVRNGAKVALRAQVLLVSTLQDALEKEEGTFREQPDGDGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7E4</accession>
    <name>A0A9P6E7E4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_862096</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7E4"/>
    <dbReference type="OrthoDB" id="1164111at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000005">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="15" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="16" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="12" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="265"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9523897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="37967" checksum="3B424FA51E7AF926" modified="2023-09-13" version="1">MARIREVWAPNLEAEMKIIRELVDAFPYVAMDTEFPGVVARPIGAFKTSSDYHYQTMRCNVDLLKIIQLGITLANDEGQFPQECSTWQFNFKFSLSDDMYTPDSIEQLQKSGLDFQRHEEFGISPNDFAELMITSGLVLSFDTKWISFHSGYDFGYFVKLLTAQSLPTTEDYFFDLLNIWFPTVYDIKYLMKASKALKGGLQEVADDLGVLRIGASQQAGSDSLLTASTFFKMREIYFDDHIDDEEYSGKLYGLGQTFSMTNGLNDPARGGATIAERDDRGSAREVHNQTPGPNGSASQQQQAVTMGLNQLAGGIPGGMTPSGYGPLTNGPPAYMRTMVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7M6</accession>
    <name>A0A9P6E7M6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_820484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7M6"/>
    <dbReference type="OrthoDB" id="2796825at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="312" mass="33914" checksum="6A1C4273763C3283" modified="2023-09-13" version="1">MVNTDTSEQLWYEKVVNASVAIGAIGYGLHIAVFYTAVSGIFKARDRAGALKWFPLLFILFSLGTINIAGSLRFNQVAFIDQRKYEGGPAAFFSAEQSNSGNVAAVATSIAMMVFADAFMIYRIHTLGKRIVITAVAAAVLVASVVMSGFHAVELINENSSSNLKYSIPYVSLATILNILITLVMAPRLLELRRQISISQDPTRAKFTNLEALVVETAFPTGLLSLIFIILYGFQKVGSLLFLPLLVQVMAIMPGLIISRMVRGYAWSNDVVGRLRNPSSSIGRTVNGDFPQDVVTLNDLGNDPKSVSNRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E861</accession>
    <name>A0A9P6E861_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E861"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23778" checksum="95EC4A2ED954AFE9" modified="2023-09-13" version="1">MTFSLVPETLAPEIIWWTPSSATLARPSDFREDAATWRDAGKETMVGTFHGAELDNQNSRVIVTVWKSLAHHQEFMSQEAYADLVLPLLEAMKGPYDVHQVIMKVPSLDLVYALSAPVTQFIYVTMRPGHGINDELVPLIEKLQKGLEGVAGCIASSWGPSTEKEALQIGIVGWRSILDRNYAVNGPLFGIVHRIRELSDVEIRYASLVSDTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E864</accession>
    <name>A0A9P6E864_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E864"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="79" mass="8967" checksum="E2E2007D04E730B1" modified="2023-09-13" version="1">MYSTCALRVPILALFETLPKRLEENGVKRKLQLACRVVLGNRVGSLCIMLLLLMDSQLIEFIVMCIPGWLQTECEDVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E883</accession>
    <name>A0A9P6E883_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_861233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E883"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040544758" description="Hydrophobin" evidence="7">
        <location>
            <begin position="20"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9524486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="12301" checksum="346B63F59F6326C8" modified="2023-09-13" version="1">MQFRLLSTSLLAIVSLAAATGTTTVTVTVPPPGQTPTPASQCNTGALWCCNNVQSANSGGVVGILLGLLDLVVAPVTAQVGSSCSPLSVIGLSGNSCSAQPVCCQNNNFSGLVVIGCSPVNLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8C5</accession>
    <name>A0A9P6E8C5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8C5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="274" mass="30722" checksum="97011527377486DE" modified="2023-09-13" version="1">MELIPSVQTLWLNHMVVPATFLANLTSLKALRLFNFYLAPETNASRIPEFAGFPSIITDFDSLKRIQLFYQQPLPAYVNLSVLFTTKDVGNIQLDDILGGSADSLQKLAIRTRYKLSANIIFLNFNKFKMLSEFRVLYTCFTLNPNVARVLKESLSAAATLSSSSSSPSNLTSFQIEIAMAATLPEQGDLKENLSSTPRLDRKDLFKRHPKLKSIVVKIIPPKLERRGGANSKDDADHALSVKKLIKRCMKKLLPNSLRFTCNNSNPTSFYSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8S8</accession>
    <name>A0A9P6E8S8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8S8"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="414" mass="48538" checksum="9DACDF76115A5EA6" modified="2023-09-13" version="1">MGATTDIQRYNENDLPEFTPMPWTLKEIRAAIPAQHFVRDTVRGMLYLARDVLMAAVVWSLATYIDPFFGKDNVKEVLTPSGAEIARWAAWSVYWWFQGLIFTGIWVIGHECGHSAFSDHKIVNDVIGFITHTFLWTPYFSWRISHHRHHSNHASMERDEVYVPKTRDDLNIPTKPHDEIEWDEIFGDTPIYTLFCLVRQQVLAFPAYLLYNVSGQKNYPKWTNHFDPNSILFTKEQRNAVIMSNIGIAFMVWGVTYSSSLYSAANVIKYYGIPWLCVSHWFIMITYLHHTDPTLPHYRGKEWNFQRGAAATVDRNFLGWQGRFFLHDVAHYHVIHHFFSKMPFYHGEQATQHLKAFIGDHYAYSDKPIFKALWESYNKCQFVENEGDVLFYRDKQGRALRRPAEQYTAKSKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8Y5</accession>
    <name>A0A9P6E8Y5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PBP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_741595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8Y5"/>
    <dbReference type="OrthoDB" id="10260248at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052738">
        <property type="entry name" value="ABC-Tungstate_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37945">
        <property type="entry name" value="EXTRACELLULAR TUNGSTATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37945:SF1">
        <property type="entry name" value="EXTRACELLULAR TUNGSTATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP" evidence="1">
        <location>
            <begin position="19"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="286" mass="31151" checksum="C8406B3AC10141C3" modified="2023-09-13" version="1" fragment="single">AVYNGGYSNASKRGICLRISNGGAGQTGLIQAWADAFIQHRVACGEDPFEIAWYLGDTTDSLALLASGAVDFAITYNAAAEQQCIDAGAAKERIYAFRDHFILAGPISNPAHLKGDDDILTMFNKIVTSGNLDVASPPNSEIRPPTRFLSRFDKSATNIKESFLFATIGQIPWAFDCCKWYHQYPRFPREALETASLLSEYTLTDYGTWISATNAVKSRLSIFKMGSDAADDLLLNPAHLLHGTRASLVHADLCDAFAEWVANSTGGQKVVETFSKDGHVLYTKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E915</accession>
    <name>A0A9P6E915_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_886080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E915"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="258"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="424"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="468"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="560"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9524729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="617" mass="66210" checksum="2B8E2405121D43DA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9W6</accession>
    <name>A0A9P6E9W6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA ligase</fullName>
            <ecNumber evidence="15">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_819095</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="15"/>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9W6"/>
    <dbReference type="OrthoDB" id="151490at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18435">
        <property type="entry name" value="BRCT_BRC1_like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044125">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 15 20" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="18">
        <location>
            <begin position="374"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="667"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="962"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="769"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="840"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="891"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="774"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="814"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="840"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="856"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="900"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9525150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1073" mass="122253" checksum="7FAE487F2616745C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA63</accession>
    <name>A0A9P6EA63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA63"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="17345" checksum="4BCCBD6C7D86546E" modified="2023-09-13" version="1">MPALIIVDDCPTWSRRTLINLFWYQLVNLNAPQYLSKVGFLMATPHEDLRVLFKVLRQNYMGRLAASLVKTEIIKFLAWPKSTASLCLSWITIKNLVCLRTELDYRTSWSAHLLTCCMPSHWLKHTFMSNSDTSSKFSVDQSTLIVRFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAW5</accession>
    <name>A0A9P6EAW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAW5"/>
    <dbReference type="OrthoDB" id="3265734at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="425" mass="46683" checksum="ABD564BA6B6E682C" modified="2023-09-13" version="1">MYARGHRWPKCAVMEKYSNCEISHSPRGFCRVLRLSFSQPSRRRLAFHLCPRGRSSSCRYSQQFTRSFQQVSFSLSSFLFRVLFFTPVTKAANNTMASSETKNIDDGNPSIQYVGDSWYRRGLGKDFLNTATISKVKGEYATLNFTGSLISVYARVNQSTTAQNFTISSYQVDGGPISNVSRTANETTYRVALFQSSSLPEGNHTLVVTNETDDLPLILDYFMVSSGEPLSTSSAPSPTSQMTSSATSFPASVPDSQNIKKSTDKAAIVGGTIGGVVILLLGLAAFWWRRRRVLGSLGNPNTVQTPMSYTHEPHRPQFKSYTNTTAYTSVSPFLTSPTLESSTSKSTQSGDVQSSSAFIDRHESLYGLSTTTQEPVSPYSSHPTTQSTGRPSFLESDASQSQSGTIISPPPPPYHSRLSLEKKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC13</accession>
    <name>A0A9P6EC13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC13"/>
    <dbReference type="OrthoDB" id="3047765at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="677"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="773"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="805"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="845"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="905"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="940" mass="99811" checksum="6C9BA8B1F70CAECC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC44</accession>
    <name>A0A9P6EC44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_769780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC44"/>
    <dbReference type="OrthoDB" id="3056870at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23929" checksum="D7BC3D3A9972642A" modified="2023-09-13" version="1" fragment="single">EERAIGYQLQCNICEQKFGKGGPEHTKNGPGYCFSTTSQTFWAKWEFWKIPASVPLFFHRSAVAHNLLDLIIELWPLSTSVGTAENIKHNTKWGSNLKPPLTNSVSPGILLFLDNTFKSAKKGVIVEKDWLRTKMMKGGILSVINELSETLVWRFCQSESANEICEILGGITKQHCNQGVAQPAVVVVDNCCHSYQAIQDKLPNTEVVLDVFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECE2</accession>
    <name>A0A9P6ECE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_870471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECE2"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01250">
        <property type="entry name" value="pro_imino_pep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="44"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="34378" checksum="1A42842791D83501" modified="2023-09-13" version="1">MSASLLQPRVAIVTGEIDFEIPTLNTTGKTWYKIIGNLTSHQRPLVALHGGPGSNSEYMEILSNITTPRSGALVVYDQVGNGHSTHLRDKLGDSLFWTDSLFLSELDNVLRKLGIRDDYDLAGHSWGGMLAARHATLRPKGLKRLVLMSAPASIDLWLETGKEYLRELPQKYQDAIINNEKAGTTNSTNYQEAIGYYSTLHVCSIQPVPEPIASGAADSANDPTVRLSMYGPLNFEVSGSLKGWTVIPDAHKISVPTLVTNGKRDQAGKTAVQPLLNEIPNVKWVEFEHSGHMAHFEEADKFTKVVSQFLGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED14</accession>
    <name>A0A9P6ED14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_837134</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED14"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="457" mass="51045" checksum="D4F6E50AC8DA13FA" modified="2023-09-13" version="1">MRVYHQWAKELGQNLLILDTPKAAIELLEKRSAIYFSRPRFGFLHQVVGPDFSTAALKYIQFCQSSRRKHRCLAHAYFGQNAPASSYKEHSVRAARELVVHLLNTDRSKDLDVKSKLSDTAALTILSICYGITPLSSTSKLAKGTEASKDTYTYYLLAVQNGLAAINKAGIPGKFLADVMPMLKYVPEWMPGAGFQTKARISGTCPPCFACTTLQTLDLEVDEGETSVGEDIVKIVAVLMYAAGSDTTSTTIASCILGLLSRPELLHRARESLDRVIKPGNLPELEDEPKLPFITAIVKEALRWREALPLGVPHQVEVEDEYAGYRIPAGLIIIANQWALLQDEEFYPDPFKFKPERFIKGDEYNYETKDPEYACWGFGRQICPGQFMAFSAIWITIASLIYVFDIEKEVAQDGSEIEPDPEYTSALMFAPESVPCHMTPRSQELARLVRASVVQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDP8</accession>
    <name>A0A9P6EDP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDP8"/>
    <dbReference type="OrthoDB" id="2939176at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="33270" checksum="648F3519C4EF202A" modified="2023-09-13" version="1">MSNSKSSTERCLHCHISAPGKSKIYDDVSTRCLKNRKGACVGCQELLDVERKIEETRRTLDTLLKEREALASTLNEYHDPLSRQFPVEIASQIFLQCLTLKPNDLITRRPPKEKSFIESVFLPGHVSEHWRNIAKRTPQMWSIICITLNRSNCISSVRVVREWLEQSGESPLSIRLAVGPTLPMIDEVVSSILQKVIVLMIEHSHRWKLLDLDVPNDLLPWISSAMLSRYPDCLEHIKLGVMHPQSDLTAEGVLNLHASPRRLTQRNVRLRQIAMNMDHLTHFYSTHSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDZ0</accession>
    <name>A0A9P6EDZ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_876524</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDZ0"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="588"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="700"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="43"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="247"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="444"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="889"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="991"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="913"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="944"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="991"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1035"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1085" mass="122511" checksum="6F17904D9A47AA19" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE10</accession>
    <name>A0A9P6EE10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrane-associated proteins in eicosanoid and glutathione metabolism</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_836330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE10"/>
    <dbReference type="OrthoDB" id="410651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17203" checksum="B1778C54EBA9082E" modified="2023-09-13" version="1">MSLTYTLPEGLPWLGGAFVSSAWLLLYQSINVSSYRKAAGISYPRAYADKEEQDKSPAALKFNCAQRSHAGAHMNTLELLPATWALTLVTAAKYPHLAASALIAFVIGRVFYTRGYSTGDPQKRNHLFTRIGTLGYLGLHLSATFVVGQAIYQSLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE40</accession>
    <name>A0A9P6EE40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vps72/YL1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_815956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE40"/>
    <dbReference type="OrthoDB" id="49520at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="6">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="161" mass="18028" checksum="C0C77A2C28027686" modified="2023-09-13" version="1">MPPKGGFKKKALSDGTSTPLTPSLAVQLSYLHQPRPFKNPNYSKNVNRRAKNLKAVLTQERERERVEREARRLEREHLMKVEPDAASRIPEEVPSYTTVEAPPSVLPHRHLCDITGLEAPYTDPATGLRYHDKSVYEIVKGLSAGIAKDYLSARGVNSVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEW0</accession>
    <name>A0A9P6EEW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEW0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="470" mass="53812" checksum="F402B03018D90A7F" modified="2023-09-13" version="1">MGRELYSTTLAKRFQKEEEEKKEVDQEWGSGWGPGLPTGEWRTTNSGWGETWHEGNQDESGWGIGPADEEFYNEDDIIGRRDNDETRQYLMQWEDDEVQVNIGQRNQLEFILGQRMTQSVETQNEIVPTDDTDIPFGVIFMALLFANALKEFRKNNNPNVETTRMSTSTSSPMLPIIEGIIRDIAFQPFIEPTSPDSGSSQTLVNSHYEGEQTDTGEYQSNLSLADMARLQQWDNGNSDDDIVYPRYSRYTEDLRQNNYANFMAQTVNQRINLLSDQPAIPIRLRTFEEETLPPVNGITVEDFNETFEDWAQLHHLLSGTNISPTLAHALISSRTHFLAYKQLDKLIKEAVKTICKMEQRSEESLRLAKHFFDLATDRGLNKVEVIRGILLERNTQQNAQTTVIDEGEGRIKTETFLLPQETNPLLLDTGDEEIEIAIATEVKTNNPLKQVFTLHLLHLNSMESPEQEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF58</accession>
    <name>A0A9P6EF58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_855628</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF58"/>
    <dbReference type="OrthoDB" id="2963517at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="137"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="139"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="259" mass="29630" checksum="54310275A397472A" modified="2023-09-13" version="1">MSAPQTTFTPPSSPLHLLAKVASEAGRRPPQRSESPMSDSSAGPASLHSRSSSDSTTASYMTNADHLHIPSSSKRLALQIPRPLTRLNLPSPLQSTDPNFVPYIRPRKRSRKPTDLTLKMRMQMKARRKELMEKASKIKSLDNSPVNERQLLVLRMVYDEITMYPCESWMVLVAIIIHRAYKQVKNWFSNERQKNRNGESIPCETEDGDKVRLRASALTICPEWSDTFFEEVVMIYNYKIQRNSQAKLSVRRPTRNSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF87</accession>
    <name>A0A9P6EF87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF87"/>
    <dbReference type="OrthoDB" id="3194584at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="489" mass="54922" checksum="29F1139A0EBC029C" modified="2023-09-13" version="1">MSSQNLQAQQGAMNPMMWANQMAQPQQMQNPMLQMAPFNMISQQIMQEAFAMAQPVDSSDDPTLLTALLNAKRSRRNFKEALNGLHGTNGHSASLWKDYYLEHKDRIDDWIEKCIQKEQGKVAGPSKLQYSPYTNGVAASSSLSNGAGEIHKPPTIKKPSPASFKREPSPPLRKPGPSRLSTATPPVKSLQKKKAKTLSDTAQPIMSSRRSTMNSLSVDAPMFGSRLPAPNASIKVPLPPSRSPSPPANIVQSARGNKFTPEDREYFIKFLGWTLKKDPDLNRTDLCALLAEKAPHHSAQSWGSYWSNNHDLPDKILASARGEISEDSEPEVMPTKKRRPVYKDPDTTDDERISHSTEDDEESDDDDDEEIQIYSSSQMSGQGSYNEADFYFAAKHIASANWDGVTSRQQWDEFQNMYPGRSYKSWAEYYRRNKSGLDKLAARIRRAETASVPMQRARPSKLPSFKKRKYEDDETETESIKRGKLGESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFP5</accession>
    <name>A0A9P6EFP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Terpene synthase</fullName>
            <ecNumber evidence="6">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_767442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the terpene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFP5"/>
    <dbReference type="OrthoDB" id="6486656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="42548" checksum="B7C266FEBC547251" modified="2023-09-13" version="1">MADIQLLRLPDLLRDWPCESRLSLFYQQCKQESSNWTTAFRPFDKKGQKAFDDCDLNLLACLTYSNRDREFIRLACDLMNFFFVYDEYTDVSDPSLARYFGDIVLDAMRLTKDRSTTSKHFLGEMTKDFWLRASAYAQAQSNGNANQPTCLQNFITTMDNYVEAVACEARDRAEGRTYNVEEYLELRRRTSGAEPTLAFIEFGLHLSQEILEHPTIKALNAAAVEMVVIVNDMHSYMREVSCGLGYHNMITVIMQQYGFHLQDAFNWLGTYSDKIVAGFNKNIAVLPSFGDDMDLRVRTYVEGLAQWIRGEDDWSFESKRYHGNRGILIRETRILTIGHVEGHYLRPENPRQLDLQRHDVISEVAIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFR1</accession>
    <name>A0A9P6EFR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBM21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFR1"/>
    <dbReference type="OrthoDB" id="1881at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001069">
        <property type="term" value="F:glycogen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005979">
        <property type="term" value="P:regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="445"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="765"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="693"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="772"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1247" mass="132490" checksum="A16322456C8ACF7F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGC8</accession>
    <name>A0A9P6EGC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sec24-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_854630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGC8"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="6">
        <location>
            <begin position="126"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="7">
        <location>
            <begin position="224"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="9">
        <location>
            <begin position="475"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="8">
        <location>
            <begin position="570"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="5">
        <location>
            <begin position="704"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="851" mass="94329" checksum="580C34AB8B70F6B5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGH5</accession>
    <name>A0A9P6EGH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GIT Spa2 homology (SHD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_766575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGH5"/>
    <dbReference type="OrthoDB" id="5588096at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005826">
        <property type="term" value="C:actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902716">
        <property type="term" value="C:cell cortex of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022018">
        <property type="entry name" value="GIT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013724">
        <property type="entry name" value="GIT_SHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12205">
        <property type="entry name" value="GIT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08518">
        <property type="entry name" value="GIT_SHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00555">
        <property type="entry name" value="GIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="4">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="4">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="771"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="431"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="943" mass="104355" checksum="4E6F9D8DD4EDB92B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGM1</accession>
    <name>A0A9P6EGM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_835817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGM1"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="163" mass="18135" checksum="6FF5B113583E0BEC" modified="2023-09-13" version="1">MGQLSHVRRWRPTVLKKEIDPLFLNPSPTSSLVLQEKTQNRMPESSLLFEFVINSRYLGRNRQGQSKIGEVAAATTSFSGITANIVGINIGESYIHQQAPCASRELYVRGFDYRVQPSEPPPPVSGALQQGQSTRVGFETMNGVVRGSYSTILEDQKTRLLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGT9</accession>
    <name>A0A9P6EGT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL34m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_790464</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGT9"/>
    <dbReference type="OrthoDB" id="431691at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3980:FF:000001">
        <property type="entry name" value="Mitochondrial ribosomal protein L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_bL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="12792" checksum="25961EA394D27B16" modified="2023-09-13" version="1">MPRLSLSILQALRRPPTLPVQKASSLLAQISPRVSLQTHHQLFRPALSSVSPLFNANPLYQQPVRFAARGTEYQPSQRKRKRKHGFLARKRSVGGRKVLSRRMAKGRKYLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGV2</accession>
    <name>A0A9P6EGV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGV2"/>
    <dbReference type="OrthoDB" id="3054765at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="56151" checksum="9713D4D3326AC737" modified="2023-09-13" version="1">MNPVHSLPPELAVYLFSLVCQAAKFRRDVIDYTHPLQLGAICSSWRQLAWSTPTLWSYIYIKVSPKNAEVQAELLKDWLSRSGTVLLTVVFRLVDEGQGRGVLQRINWTDFSDHAVYLFAEKLLFIIAGECTRWQSLEVDVVSSGCTDILNDTWRRIPHLQYLRIRATEQGPDNLHFYEQAPNLAFLFLEARETLLFGLRHWSSDCWKSVTTILLDNYATYDMAAGMLIACHQTLRHFHLQSLDTQNLQTPLEVAARRADFPHLETLVLEGAAHDNPETLFPVFLSMPKLRKFEIAITGGSELNGVQNFLAHSDITLEVFRIRLFGADQGDAEEKGEAMIKLLRPHFATLHDLALLIPLLNEGSYRFIKVFHRLLNRNNYDSISPFNMCESPLPKLSFYEFSRGSFGELREFDKPWLPLVPVLEMVQSRWKKPIDPRHNQLSKLSLPGRYQDWVVDYLQKEINEGLLVNFVKVTHIPRSMEWYFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGV9</accession>
    <name>A0A9P6EGV9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6589 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_929056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGV9"/>
    <dbReference type="OrthoDB" id="3266963at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046496">
        <property type="entry name" value="DUF6589"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20231">
        <property type="entry name" value="DUF6589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6589" evidence="2">
        <location>
            <begin position="382"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="917" mass="103412" checksum="EC71DCE353DC9824" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH94</accession>
    <name>A0A9P6EH94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_893770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylthioribose kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH94"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34273">
        <property type="entry name" value="METHYLTHIORIBOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34273:SF2">
        <property type="entry name" value="METHYLTHIORIBOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="361" mass="40117" checksum="E6B410F842C3AC56" modified="2023-09-13" version="1">MKKYDLTTEAGTRAYLASDLNLDVKSVKGFGDGSLNFVWRVELNTQYKGQNSVVVKHAAPFALADQNAEIGVGRLTFENNALEMISSERSIIGEDELVTVPAAYHYDSKKHVLIMHDVGSLPTLYDLISAKRTLSADMLTVIGTKLATFIAGVHNWGRNNEKVHAKLSNNKAGRTVMDDLGYQTVIPKAAEYGISDPLLATVVDALADEDRTSQETVIMGDFWTQNVMVDLEDTGSGEKALKKIWIIDWEGCRYGTPAVDVTSLVGDCYLLSRFYEQKSAEVLRHSFLKTYASKAFSKVDPLRVVTGVGIHWIMWAKIVGGENTSHAEVKECMEKGVDYIHKSWEKSEGWLRSSLIRELVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHQ7</accession>
    <name>A0A9P6EHQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_835397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHQ7"/>
    <dbReference type="OrthoDB" id="2791511at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="211" mass="22938" checksum="91DBA2F373578956" modified="2023-09-13" version="1">MDTVPGLALVDGLPTFGLSATLSSLSSQLVNPSLWLTLLATLVILSSLRAAILFFRTAPKAPRKAQISIIPGVQEKKDIVSGNGIKGSSLNNNSVEQEKGGRKTLSSAFLGLIKWDSLPSLPLPRRGNGAQSMSETERGRWTSQPQSSRTQTRSGRPAFQHPQPAIYQSDVPVSMAKMIMSRHTFRRPSSRPPPVRNANAPQFQRKLPSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHY8</accession>
    <name>A0A9P6EHY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endoplasmic reticulum protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_764903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHY8"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF26">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="136"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="409" mass="44870" checksum="B94C7E99D22EBC6F" modified="2023-09-13" version="1">MPYAFCNQPWKGLYLTYTAITLLFVRLPFWTLLYLSKKSWTLAKCLNLRMVRVLVETLTQTGPFTEVHNHLALAPGKGVNGVWVEPVNNLITGVLKEWANISKVESIRIPGYWLHKKGSSIPIGDQPHPDEKLIYALHGGAYIRCSAHPSDPTSAIQRGLLKHVTSVTRSFAIEYRLAVEKPFGEAHPFPTQIIDALAGYNYLINVVGFNPENIIIVGDSAGGNLAYAFTRYLLDHKGTNVNGATIPAPPGALLLLSPWVDLSSSHESLPRGSLARNRSSDYIGSPDGSASSAKSAFLGPHGSDAANTNTYISPGSLHPDVEINFTGFPRTFILAGNAEVLHDSILTFRDRMVKDLGEGDGIEEGDGKVRYIDVADGTHDFLAMTWFEPERTMSFKEINNWVHGASIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHZ4</accession>
    <name>A0A9P6EHZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9529014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHZ4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="57" mass="6229" checksum="0E6D78D6413F8510" modified="2023-09-13" version="1">MTALLNLVSHLAICGRLSETGSKVSESLKFRRHQSKAANGECVGRLTLVVSRRFVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI30</accession>
    <name>A0A9P6EI30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI30"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="7902" checksum="7D72B2D27DBAE93F" modified="2023-09-13" version="1">MNIKTSYIGATQVFTPKSPGHSGVSPEHYDDTERLELASRRSRRRYVQYNRRKVTREPRISYRLWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIH3</accession>
    <name>A0A9P6EIH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIH3"/>
    <dbReference type="OrthoDB" id="10014216at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF2">
        <property type="entry name" value="PHOSPHORIC MONOESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="28589" checksum="E7C22DCADE760025" modified="2023-09-13" version="1">MAEGVPPVSTLPYPAIHADKEFIVLSDWDGTITTFDSNDYLTDNLGFGKEKRRQGNLDILAGHDNFRDGFKKMLASVVKNGHTFEECKKILKDNIKLDPGFKDFLTWCKELDIPVIIVSSGMAPLIHAVLTNLVGENIANGIEVIANDVTVSPDGSWEIQFRHPSSGFGHDKSQAILPYRKLPKPPTLFFFGDGVSDISAARYADVLFVKTKSDGENDLSVYCQRERIKHILFDDFSKALPIVQAIVAKQKSIDDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIJ9</accession>
    <name>A0A9P6EIJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIJ9"/>
    <dbReference type="OrthoDB" id="2905268at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="36267" checksum="4036858486FC6028" modified="2023-09-13" version="1">MCIYGLTVFLETPKSLRQGRLIYVFISFIILGLYCFAELPLAYYTYVLLDKPCTAMDTARLAGKLSGMWWALADTWASVVLFWLGDGLLVYRCYVVWTNKRYVTILPGAVYLAAIATSAWFTVASQRPSTDKSSRVAYTAFSVLSALVSFIVTSLIAGRLLYMRQKQSKILAGAAVDSKMYFGVISILVESAVPLAIAGIMSAVTLWAKMDKYEIANDVFIVLWTSLTALAPQIIILRVTLGRSWAHGSHTLKESHLSTLAFQPRTLHDSDALGHEFEDSTHRNSSELQDPTRLEDLEVAEKPTDRERNINENIRLRGGSFNLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIM4</accession>
    <name>A0A9P6EIM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_262564</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Golgi apparatus</location>
            <location evidence="6">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAPP small subunits family. BET5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIM4"/>
    <dbReference type="OrthoDB" id="3364529at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14855">
        <property type="entry name" value="TRAPPC1_MUM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF16">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4 6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="24136" checksum="D192D4ADE7F45101" modified="2023-09-13" version="1">MTIHSLYIYDRHCTCVYYQDWHRTNRPKVAAEGGMLPAVCATIYPTSQQPEANAGTTLTFTSPRNTLTSTTGVVVAVSDSQQQPAPLLQANPTSVGTSSSGLPFDEEAKLVYGVVISLRNMIKKLAGRDESFVNYRTSGYKLHLFETQTGYKFVMLSDPKADSMRFILRQIYVGPFLEYVVRNPLVKMDSREQGIDNEYFRASVDRLIRGLSVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL36</accession>
    <name>A0A9P6EL36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_787991</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL36"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="553"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="620"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="669"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="698"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="768" mass="86552" checksum="D1B10157391DF52B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELX2</accession>
    <name>A0A9P6ELX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_109829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELX2"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="12781" checksum="7087455596AFF7D5" modified="2023-09-13" version="1">MWSTTLLSPFVQQHQPSLPRHRCRMLMGSEIQQRTLAQQPLRFGTVGKIGGIEHHLASQIPPLPPKSAWSRFRPAFLEKRRKLLEFWLTRVLLHPEIGGREVVREWVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMF9</accession>
    <name>A0A9P6EMF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_77614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkylbase DNA glycosidase AlkA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMF9"/>
    <dbReference type="OrthoDB" id="415889at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032993">
        <property type="term" value="C:protein-DNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032131">
        <property type="term" value="F:alkylated DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000004">
        <property type="entry name" value="DNA-3-methyladenine glycosylase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051912">
        <property type="entry name" value="Alkylbase_DNA_Glycosylase/TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003:SF5">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="5">
        <location>
            <begin position="134"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="287"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45316" checksum="2CC50E70AB35DACA" modified="2023-09-13" version="1">MPATRSSARLSAQASSTSTLATEEAPVQATPAKKATQKRKAESDSPLKDESAKKAVKKKKKAVEVSNEPPRELTDEDEKTKLLPPVLSFDFEEAKEHLIETDHRFAELFTKMKCNPYEVLEQVHPFRALSVSIIGQQIAWQAARSVTHKFIRLYDPSLPEKPTEEERAAITFFPGAKQVAQTDHQSLRSAGLSDRKAEYIKDLATRFADGRLSTEKLLKADDDELVEMLTEVRGIGRWTVDMFSIFSLRRPDILPVGDLGVQRGMLVWFLSRYSSAHNFILSPEKIGNKKKETEEDDSTSTSDQLAEPEGVSCVPPATTERTEDIPGLPPAFTPSIKKTLANPSVDPGKPIPPLPTGVTVSLLQSRLSGKKTAKKTFLTPEEMTALTDPWKPYRSLGSYYMWSLASSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMP2</accession>
    <name>A0A9P6EMP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ataxin-10 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Copper transport protein 86</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_833406</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a role in the regulation of cytokinesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMP2"/>
    <dbReference type="OrthoDB" id="379794at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="8">
        <location>
            <begin position="712"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="446"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="564"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="605"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="681"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="454"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="514"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="803" mass="89384" checksum="DE1F802C5EFB0CF8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMS1</accession>
    <name>A0A9P6EMS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMS1"/>
    <dbReference type="OrthoDB" id="2011986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="50993" checksum="E90EA0B8AF930217" modified="2023-09-13" version="1">MAPVPQEELGILENVIQIRNRLTALKKDRGEFIKASDVNQLYQQVVKQITKLNDVRSDVNIYNNRLDTTLADVFSLLSLFYLTIGKTRDAPATYCQIASMRQILNHMNESAVYNETDLAPFHKRLAELRQIVQQDAESNKHPKAITKLLERQLNETDAVVKQLQDSLSVLSPELQPVHQKLVTIRRQLVALAAKEGSQKAELKPLLEELRKIESTRVDGKFLGPGGVVPASQAVCSSLLEECFDIIQEIKAHEDSKNVGSSLKPIYDRLNEIRAELESLVMTHRWSLRETDLWNYSLSLQEIDKMRVDGKFVDSEDNRPPGQYVLLYLLRRCYGLIYRLLSSSEPVSEELMPIANKLTTIKKCLNEVLKYGGTFNARDLYPYQLALFQIDSMRKEGRFVGTDGSIPEGQGIINANLSECHELVELLKESMEEEENGDDDDYDYSDEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW7</accession>
    <name>A0A9P6EMW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="8">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_891616</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="8"/>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW7"/>
    <dbReference type="OrthoDB" id="2525337at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF17">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040296787" description="AA9 family lytic polysaccharide monooxygenase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="10">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9531732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="26047" checksum="23E625C1E6C148B5" modified="2023-09-13" version="1">MQLKSLVVLASVLSTALAHTRVWSIWVNGVDQGDGKGVYIRSPPTNNPVKDLTSSAMACNVNNSPVSQTVNVKAGDTVTFEWFHDYRNDDIIASSHKGPVLVYIAPTSSNGAGPVWTKLYHAGNDGTWAVDKLLASKGQHKVVIPNIPAGDYLLRPEIIALHEANVAYSSNNLRGAQLYMNCVQIRVTSNGSQSLPGGNSFPGTYTSSTPGIVFDIYAKGADMTKYQIPGPAVWSGSAGGSITRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENH3</accession>
    <name>A0A9P6ENH3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENH3"/>
    <dbReference type="OrthoDB" id="6244550at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45924">
        <property type="entry name" value="FI17866P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45924:SF2">
        <property type="entry name" value="FI17866P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="19"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="849" mass="91462" checksum="605DFFB12FA15AD0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP34</accession>
    <name>A0A9P6EP34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CDF-like metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_848379</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP34"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF12">
        <property type="entry name" value="CATION DIFFUSION FACILITATOR 1 (AFU_ORTHOLOGUE AFUA_1G14440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="115"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="329"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="405" mass="44760" checksum="8934853A5808DA3B" modified="2023-09-13" version="1">MSDKGSPTFQEENPKTPWADYRPPSLEHVPSHGDVENAPGSSGLNPIDPFLLRDGLVPEDDIAGLRRRKKGKQVAKYQTEQNDLIKSLLKPMEEHTEDAIQEEEAARVPVKIAIYASLAANVILCIIQLYAAITSLSLSLLATGIDAVFDIGSNVLLFWLHRKAGKLDLNKWPVGGARLETIGNIVYGFLMGSVNLVVIVESIRNLVTKPDSDLKDFHLPSIIAVAAAFGVKLALFIYCFSLRNKSSQVLVLWKDHRNDLFINGFGILMSVGGSKLAWFLDPMGAIIIALGVMISWGRTIYGEFGLLAGKAAPHSFLQLIVYKAATFSDDILKIDTVRAYHSGPDYFVEVDVVMDGSTPLWKAHDLSQQLQDKIEVLPNVERAFVHVDHEWTHAPEHRKAPKHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPK6</accession>
    <name>A0A9P6EPK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPK6"/>
    <dbReference type="OrthoDB" id="2683368at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="300" mass="33041" checksum="5180C4A9CF12D4E9" modified="2023-09-13" version="1">MSRIAVGLPSNPRARLASSPSPHPPPTRGRPQGQLPSPRTEAPRSLRSASAARPRQVETYEFPTKDVRRIQSRSRPGHDGNRSARRTSISSTSTTSSGGSSSSSLWERGSERSYSTAASEDVPEPEQKAVINTEGSVLGSLLDTTYYWNRATEAASALSQGVSSAWSTGVASQLESDHPEDDSHLLKVMRAYHLSKARTPSELPDWLFDERERGTKAGFAHVSSIEVSSDTPSRSKTQTQRRRYGQVSQPTQFIPSQEFPVDKEPTYFRGSPEPIPSRLPDGVNRLKTLRDRQRNAPAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ19</accession>
    <name>A0A9P6EQ19_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_784048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ19"/>
    <dbReference type="OrthoDB" id="63935at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF50">
        <property type="entry name" value="UPF0659 PROTEIN YMR090W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="30873" checksum="5AC0DBA7162127C5" modified="2023-09-13" version="1">MSLNVLAAGASRHIGYHTSVRLLEAGATVTFLLRSPEVFDGDEVIQKYVKDGKAKLFKGDALVEDDVRSVWAEASKEQPVDLLLFTVGFNGSPSFSLTKGVQIKPANLATQCLFNILCGIPKTEPNSSSGSKLKLITLSSIGASRSARAKLPIHYKMLYGYLIAGPLIDKLGMERVAAHVSGQEWDVQGDGEPDEDIMGPSWRERQGLPAPGTLESVVIRAGTLNDGECRADNVEAGRKPYRFVIDKDQVSGSISRKDVAHFAFDLITKRWDELKNHTVNVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQT8</accession>
    <name>A0A9P6EQT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_846042</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="572"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1047"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1095"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1197"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1281"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1313"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="333"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="768"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1057"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1373"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="427"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="473"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1624" mass="180003" checksum="2722BEE917B01DF5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETJ6</accession>
    <name>A0A9P6ETJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase/oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_333148</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETJ6"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="33"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="156"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="270"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="453" mass="50016" checksum="6BA876D9B364CC16" modified="2023-09-13" version="1">MAAHPIVEYTSEASWAMIEDKFSPFAKETLTKVIKFLEDEILPAVQVAHAQMPQESAKRWQTIIPVVEDLKAKAKKQGLWNLFLSKSHYPEHGVPLTNLEYAVMAEVLAHAGHIGPESMNCAAPDTGNMEVLARYGSPEQQQKWLLPLLNGEIRSAFAMTERHVASSDATNIQTSIRQEGNDIIINGHKWYISGAGDPRTKVHLVMGKSDPSNKNSYNQQSVVIVPADASGVKVIRPMHVFGYDDAPEGHCEIIYDNVRVPLSNLVLGWGRGFEIIQGRLGPGRIHHCMRSIGVAQASLNLLLRRVSDPSRKTFGKLLYEHGTVIADIAKSRAEIEAARLLVLSAAQQIDKHKAKGALKEIGIAKFVVPSMALTVVDRAIQCFGAEGVSQDTELASRWAQLRTLRIADGPDAVHIQQVGQRELKRVPGLTKKAHEIKKKEESLMQKYGVKAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETP8</accession>
    <name>A0A9P6ETP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_780309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETP8"/>
    <dbReference type="OrthoDB" id="3258294at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="33858" checksum="4687BCE9B9ED05EB" modified="2023-09-13" version="1">MQSESDQEIFERLFKRSKIPLYTCLPALTWVLYDYLLTLSEEAKYIWPQKRNFGTLTFFWIRYYTILLVVFDVAQIHSFAIPGVPTVDVCVAMDPTIRVVGALSLWAVEIVMQTRIYCLYGGSKKIAFYNGALFLASIVAWVYIMYNTAQHRKVTISSATKYHLPGCPTINGGIRWAVWVPATIFEANLFFLALYRAFLSISARTKINKRNSLIRVLLQHHLAYFLGITGVLIMSNVMAVGTPFIPWFGYAPFHAAVGIMTSRMHIHLIKFSEESIDNAYDTTWTTTLDTSEPLSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUB5</accession>
    <name>A0A9P6EUB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_801703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUB5"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="263" mass="29327" checksum="0FF2D0B55200AF9E" modified="2023-09-13" version="1">MSEKQCRICREGVSAERYSGRLIRPCLCKDSMISYAHIECLIRWRNKSASSSSFFACPQCHYKYRCARTRVSGLAGNKVVIGGLSGLLFTCIVMVASFITTYFMDALEEPSSYSGYFFYVSPFAVAQDLMTAAFRVIRDGQLDEILSQPVVQSPRSNMSSSHYTPPGILRRFIHHFLIGLPLVGAGSIVHVLITLGMLAPAQFIARYRAVRSRRSSSKDVAALIVIALLAAGAIRALFQVYRLTERISRQALLRIEKVILEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUC5</accession>
    <name>A0A9P6EUC5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Topoisomerase I damage affected protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUC5"/>
    <dbReference type="OrthoDB" id="10260741at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21449">
        <property type="entry name" value="DLC-like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14722" checksum="B5A982315A6107B0" modified="2023-09-13" version="1">MASGLRSPPPSRSSASSPRPRPKFDSDLLRAYMKKLLSSKLQGNLWPEAKDRDKVKPWMKEIGERVKERMLEIQPRGFKYVVLTQINENLGQGGRADMVCHWEDTDVVAQEVFYNDSLICICIALAISNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVG9</accession>
    <name>A0A9P6EVG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_753362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVG9"/>
    <dbReference type="OrthoDB" id="5413003at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038014">
        <property type="entry name" value="Ies1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37287:SF1">
        <property type="entry name" value="INO EIGHTY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="432" mass="47240" checksum="4D695D84EDE86F1F" modified="2023-09-13" version="1">MASAATRSSPQPRRVVPIKRADGEPLTRGDIQYDFLNAVFGDSKAVFTDPYASGKDGEPADKVCFRELYIKAILHSPKATKALKDKMGEPSSFAADFGMLSLLVNVGRVNTTMSFFPEMKTTIRTYHPIPSLQRTNGNMQDAPRIKHILKTSLLDGEGKSPPATPGDVLSRAKDGPTPSTSVTNLIFVLAHHTGAIGQAHFHGQFDFMDFFLRTEVSSVSRAQAFLWLCYNYLESPAPLEDEYDEEIPENPFCDPVKKSSPPSFIFLTQDEMTLENQESTEDIAMTDKLMNQRTRIVQTHGAKEALKGAAKASAKGSSSGSVADDDAGVDDEASASVVAEEPKPKGKKATVSTLSTKGKGKRATGTTKEKPKVVLTVEKPKEIKAIPKVPDMDDDDQMIDAFVKRLCLFTCLPLPRLIILFRASFSTEANWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHT6</accession>
    <name>A0A9P6JHT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_747425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157996">
        <property type="protein sequence ID" value="KAF9521717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHT6"/>
    <dbReference type="OrthoDB" id="3031173at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="15830" checksum="C141FB19D4B6A59A" modified="2023-09-13" version="1" fragment="single">EGISNQFSVCHFTWYNRYSKSGKGLNPHIDPASAQKPGTQRRVHTSQSVPRASNEQKDHLYEYKRLKESFGPVFDWLRELASNPYNYKILSEYVEILPAGEPSPVHPFAGFVLNINVSTRVHCDWQDHDICLILVISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHU4</accession>
    <name>A0A9P6JHU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158038">
        <property type="protein sequence ID" value="KAF9521509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHU4"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38534" checksum="476579BAB04EC3DA" modified="2023-09-13" version="1">MSPPRNEIIIAVMGPTGSGKSQVVDLLSGTNWASSRLQVEARKVRCTTAKIPCGKGKNSKKRVTLVETPGFDDTSKSDAEILQMLVDWKTETGRKGTKLTGILYLHRITDKRLNGTPDRNLGQLKGEGQNIEQRVMFVTTMWDKVQGDPKKLEEGQKRHSELKQYWNPILQKGAQIEEFSNTKAAAMELISKVIQRKQRVEAGVTFQQEQLPGALNESQAAQTLFSQFQRRIAEHRAVLLDIERAAHGGNVPAVMADLNAQRERMEADLDKIIEQGKPMKLSFMTKLKNGIFGKKTEGYVMEFLIGSCGFSLIGASIVLTFDFAEPHYNLPFPSFGLLWNHGLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHV7</accession>
    <name>A0A9P6JHV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_778366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158007">
        <property type="protein sequence ID" value="KAF9521643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHV7"/>
    <dbReference type="OrthoDB" id="3270451at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="684" mass="75424" checksum="B32607B7608577FB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ81</accession>
    <name>A0A9P6JJ81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ81"/>
    <dbReference type="OrthoDB" id="2536450at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34862">
        <property type="entry name" value="SPARK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34862:SF1">
        <property type="entry name" value="SPARK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040105579" evidence="1">
        <location>
            <begin position="18"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="260" mass="26672" checksum="C5D3C3E6D88E4605" modified="2023-09-13" version="1">MFLSALIIASFVALGSAQISGIGQQCMTALEGVLASPDASGCLNTGALLALGISNNSTFVPALNTWVTGLCGQPACSNATLSAVTQNITSGCSTELKALGVNTDKDSTSQLTQDIQTYYPTVRKVFCLKDGGNLCINETFTNLANSLGGLSLASLSADVTDGIKTLTNLPNNITCTDCIKETYNIVVQDFPKDQSVLQAAAKAKCGASFVDGSAPSTVSQSANSAVQSTKSAALGHRSMFADSFFGAATLLIVPILSTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJJ4</accession>
    <name>A0A9P6JJJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS10m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S10, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_840033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the mitochondrial small ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJJ4"/>
    <dbReference type="OrthoDB" id="366214at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000003">
        <property type="entry name" value="30S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="8">
        <location>
            <begin position="102"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00057689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00065857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="27183" checksum="6FDA4E8A86758B79" modified="2023-09-13" version="1">MAKNSSKETKIPDVLAYTVEAVPGQLAPSVASTPGELFGSAFSYESLGLKMDPRTLPLPLPKNFNPLDTALTEEQYASSLVHGRSVVEPYRHPRTHSIPVASIHFRSHHVELLNLFTHFASHAASALGIPIGGVASLPTKRTLWTVPRSPFAHKKAQENFERKIHKRAIKAFDADGEVVQRWVAYLRTNALAGVGMKVTTWDRVPLGIGNAKILKQNQDSATNSRLTAPNKIKQLGEEIIKEEQRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKK9</accession>
    <name>A0A9P6JKK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Member of the major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_861426</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKK9"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF84">
        <property type="entry name" value="VACUOLAR MEMBRANE AMINO ACID UPTAKE TRANSPORTER FNX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="42"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="57401" checksum="00F39F29CFD80E28" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKM6</accession>
    <name>A0A9P6JKM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKM6"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="61" mass="7021" checksum="82B5C39BDC44FD90" modified="2023-09-13" version="1">MINELIKTCTGWMMCGFFSTASQQSKAAAEFHSRVVDVLDWGSRKWYNVSRNDRGVIFEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL86</accession>
    <name>A0A9P6JL86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_861018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL86"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="8">
        <location>
            <begin position="95"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="200" mass="21758" checksum="1AA6F3A52ECA7632" modified="2023-09-13" version="1">MDQAPHFVINNSATPDIDTVVRPAHFEPNGSQLSKSVSHGQTASDFKELRESRKSARVVTKDVKYASSTTEETSRNTTSLHPIQLRLLNCGSVARDHLALERTYLAYVRTSLGLGSAGVALMQFLLLGHTTKRFAKPVGASLVAIAIITLALGARRYFTVQRNLVDGRFQTAAAEISLITFSLSSVVAITVVLMIIRSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLG8</accession>
    <name>A0A9P6JLG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HCP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_871189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLG8"/>
    <dbReference type="OrthoDB" id="2148946at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="19636" checksum="D8AE99BF65CD8991" modified="2023-09-13" version="1">MTPQDYLQLGIQHHEANRLAESTRYFERAAKENGGCGVGMLMYGLALRHGWGCSKNEGLGFKWVQKAAESAVGDLERLRTGKVDTGSVQAELVLAIYEVGQCFFHGWGVAKDQKMGVSYYMVAARLGDGDAQGDLAFCLANGKGCKKDKKEAARWYRAAVKQGQSDVGLAWIYKEKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM14</accession>
    <name>A0A9P6JM14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Erg28-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_818248</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM14"/>
    <dbReference type="OrthoDB" id="6485510at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9525691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15495" checksum="E1B482D4774506F0" modified="2023-09-13" version="1">MSSFLPTSAGNLAYWQLFVAVTALFNTVQNFVTVKLTRRVYNNVPENSVTPLQARTFGVWTLTSAVIRLYAAYHIHDKSIYDMAFLTYLIAFGHFSSEFFIFRTCQLSTGILGPFVVSTTTLIWMFSQYEFYVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM20</accession>
    <name>A0A9P6JM20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Caspase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_909313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM20"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="674" mass="74911" checksum="993D5654F8B6458C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMG7</accession>
    <name>A0A9P6JMG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_939915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMG7"/>
    <dbReference type="OrthoDB" id="3163890at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="117" mass="12786" checksum="8C4F7AA17B2FCF9E" modified="2023-09-13" version="1">MAMQLDPTVRPPVDAPWYIIAWIMEGCDEVKLDGSIKALAEHRGTYAHAQKMRASMTYAFGRIHGMGSTPWVLNDATTRASGNPSMSEKVATYMISLKNRKVRAGEAATSARAITTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMU1</accession>
    <name>A0A9P6JMU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896594</name>
        <name evidence="3" type="ORF">CPB83DRAFT_896599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMU1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7045" checksum="A3D250D8ACF0B902" modified="2023-09-13" version="1">MSKQPPPRSPTQTTKGKKVAKTPLHVPPGFVLATATDELAIEAEQMKQTLRAGQAAAGVLSGDALGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN54</accession>
    <name>A0A9P6JN54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glucanase</fullName>
            <ecNumber evidence="12">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_857011</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="12"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN54"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.40:FF:000001">
        <property type="entry name" value="Glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF4">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 12" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040535188" description="Glucanase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 11">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9527027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="450" mass="47436" checksum="999CE5409136F378" modified="2023-09-13" version="1">MFKAIVAFSSLFPFVAQATAPLYGQCGGQTYTGDTNCAAGATCVYSNSYYSQCLPAGTGGSSSLTTHSGSTSVPANPTSGSSSAPSSTSTPDAGNPYNGYTVYLSPYYAAEVQQASASITNVGSKSKALSVGNIPTFTWFDVIAKTSDLGTYLADADSLSKSSGKKYLVQIVVYDLPDRDCAALASNGEFSIANGGEANYRMYIDRLVAQIKKYPNVRVVAVIEPDSLANLVTNLNVAKCSGAQTAYKNGVTYAMQQLNAVGVYMYLDAGHAGWLGWPANIDPAAQLFATLYKTAGSPQFVRGLATNVANYNALSAVSPDTSITQGNPNYDEMHYINALAPKLQSQGFPAHFIVDLGRSGQQGIRQQWGDWCNVKGAGFGIRPTTNTGSSLIDSIVWVKPGGECDGTSNNSAVRFDAHCGQSDALQPAPEAGSWFQTYFEQLVNNANPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN84</accession>
    <name>A0A9P6JN84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Leukotriene-A4 hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_857773</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN84"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000003">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000004">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="12">
        <location>
            <begin position="483"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="135"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="279"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="596"/>
            <end position="598"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="643" mass="72567" checksum="7F3D75368E540176" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNS9</accession>
    <name>A0A9P6JNS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNS9"/>
    <dbReference type="OrthoDB" id="2823912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="12"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="688" mass="78902" checksum="2CCB173200C7D88B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP72</accession>
    <name>A0A9P6JP72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_907111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3056903at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15517">
        <property type="entry name" value="PHD_TCF19_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="1181"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="627"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1127"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1585"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="627"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1128"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1585"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1606"/>
            <end position="1620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1620" mass="182081" checksum="BD378C9F66CF7995" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPG5</accession>
    <name>A0A9P6JPG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc-finger of the MIZ type in Nse subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_391212</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPG5"/>
    <dbReference type="OrthoDB" id="26899at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="12">
        <location>
            <begin position="244"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9527555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="39546" checksum="274160DBA9B15FDF" modified="2023-09-13" version="1">MAPRTLTRRKGRQNSDEIEDARPTQDGNMEEVSDDDHQPRRAKIEKKGKGKQRAVEPEEDDGDGDGEIDMEDSDDEDRIDVANFPDQPLLKDSQLSKLKGISDDWDSMRKMIGQRSDIYKDVAAAMAEAGETDMQNSKALLELDRGIKEFIDVGEEMRAHSESLGAIYQKIARGERIDNALELYEEGFKERVDAYASKTARQKYGKDERYHEFHSSIWEVTHHGEAMPPVTDFIEKEENGDSDSDEDIQVGGVTQNFTCPITLTTLVDPVTSRVCKHSFSRDAIKELCRDPRREIKCPASGCNQKFRFADCLPDESLAKKVRAHERRVKAAARDSDAEAIDSDAEEVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPW3</accession>
    <name>A0A9P6JPW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL2m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_792041</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPW3"/>
    <dbReference type="OrthoDB" id="268576at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000128">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="10">
        <location>
            <begin position="97"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="9">
        <location>
            <begin position="231"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="335"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9528109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="43608" checksum="0928AD803308F67B" modified="2023-09-13" version="1">MLSTLRGSSSASLLLRSLAPRLRPAQTYLPTRTYASEIWKNVKKSELKDALVRTTELYKTYKPVSPGIRHLRRPLNPHIFPGRPLRFLTVAKRKNGGRNHSGKITVRHQGGGHRQRIRVIDFMRENPGIHDVVRIEYDPGRSAHIALLHNRDPAAVGSAKWSYIIATEGMRAGDQVQSFRQGIPDDFVPGFKGSMDSKKKPNSRSNQTNQEDTEAASAQSLALGLLRSMTLKPGNVLPLRLIPTGTVINTISLKPNGPGILVRSAGSFGQLVAQEDKSRYVHVRLQSGEVRKVLGDCCATIGKVSNSLWKNRSLGKAGRARWLGIRPTVRGMAMNANDHPHGGGRGKSKSNKHPVSIWGWGTKGTRTRKPGPKGPKNSNKMVVRERPRGKEKQGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQC3</accession>
    <name>A0A9P6JQC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mss4-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_906627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQC3"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="293"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="428" mass="46637" checksum="04C88613AA08CC2C" modified="2023-09-13" version="1">MPDNNFTYIEGSCHCELNCFSVAFQTAQLPISTDLCHCNTCRHASGQLAVEQVNIEGVPMKSANPGSRRGARSANGGSRSRSASPNPSGRTNKHTLNGAKSGGLLAVPTVLGPVVVPDDEPLKPLELNDLVAYKSSPKRTRYFCRGCSSHLFSVGHTDGQDTWCVGVGALDDIDGIVQVGYHMWLGDTLDGGIADQLPSINGVELPRYKDGQGSDQVPIGWKADETKVKAPERLLAYCHCRAVQFALCRPSEQSSEPTRAYPDLLYPYDVTRLSKVNNSKDEKWWLRASNSKYLAGHCMCTFCRLASGFDVQSWGFVPLADMVDVESGKSLNLEADASRPKGLKRYISSPGRYREFCGTCGASVFWWDAGVPDLVDVSMGLFDEKGAGGARAEDWFEWCTTRVSFEEKANNKDLAKGLGEGLKATIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQG4</accession>
    <name>A0A9P6JQG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_268785</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQG4"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="363"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="882" mass="98420" checksum="C3F4C73831C5B8A6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQR6</accession>
    <name>A0A9P6JQR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_766272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQR6"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052909">
        <property type="term" value="F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 9 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="11">
        <location>
            <begin position="21"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9528830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="290" mass="32630" checksum="904AFC3B94707446" modified="2023-09-13" version="1">MTNPIFNTARFGQHILKNPQTCQRIVDAANLKPTDRVMEVGPGTGNLTIKILEKSKSVTAIEMDPRMAAEVIKRVQGTPEQKKLAVVIGDFVKADIPYFDVCISNTPYQISSPLVFRLLSHRPLFRVAILMFQREFALRLVARPGTALWSRLSANVQLYAKVDNIINVSRNDFRPPPQVESSVIRLVPIDPPPPVKFEEFDGMNRIIFSRPNKTVRGNFQAKGVMKMLEQNRSTWLSVQNKVVNDDRSINKIVDDVLAELGHSDSRGSKMDVDDLLNLLAAFHEVGIHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQV3</accession>
    <name>A0A9P6JQV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7727 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQV3"/>
    <dbReference type="OrthoDB" id="2110422at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056144">
        <property type="entry name" value="DUF7727"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629:SF1">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24853">
        <property type="entry name" value="DUF7727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7727" evidence="2">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="17060" checksum="5AD5E60A98131DDE" modified="2023-09-13" version="1">MGNLIWHEYSRFVSITASVYAVWASFFGLIYRKFFWDFVGGTLRDPGGIQPAPGAALFITLIVKAPVVPIISMVLGMAILAIELPAPMVKQLSIYRSLPLRVILLLFQVFFTILFYQGTNAAIWSLIAAGCYIRAISLGEVMEEAKANRGKGGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQZ1</accession>
    <name>A0A9P6JQZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_188744</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQZ1"/>
    <dbReference type="OrthoDB" id="10261027at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="225"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="498"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="594" mass="66507" checksum="0C30E19EE8752CEC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR26</accession>
    <name>A0A9P6JR26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_853074</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR26"/>
    <dbReference type="OrthoDB" id="2548929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="744"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="428"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="836" mass="92826" checksum="12BECB1374884ECE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRJ8</accession>
    <name>A0A9P6JRJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polynucleotide 5'-hydroxyl-kinase GRC3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polynucleotide 5'-hydroxyl-kinase grc3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_849803</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRJ8"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="9">
        <location>
            <begin position="343"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="775" mass="84530" checksum="F9CDFEC353FAE41E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRK4</accession>
    <name>A0A9P6JRK4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRK4"/>
    <dbReference type="OrthoDB" id="2960209at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="200" mass="22836" checksum="42D9CDB94B3BD6A7" modified="2023-09-13" version="1">MHGMGMGHHWGLYRRGPSRLLWFIIGAGAATWWIKKRDGHFGHCGPRPIDTALPQSSPSTDNGYAHNWHQRWHAHMNEAQRSMPTPPQVPADVPAEKTPVDFTPPPQVQYQAAPSYPQQQQQPQVNAAWGWDHEREHIERISKQATDAMVDLTESTLESVLATAESLKAKLAEQRAQREKQQKLIDRQLEEQRKNPPRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRM4</accession>
    <name>A0A9P6JRM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_875400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRM4"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049017">
        <property type="entry name" value="Nab2_Znf4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21803">
        <property type="entry name" value="Nab2-zf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="97"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="293"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="523"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9529700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="596" mass="62599" checksum="21FD1F8C1C4361E2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS62</accession>
    <name>A0A9P6JS62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_761068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS62"/>
    <dbReference type="OrthoDB" id="3013446at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="943"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1011" mass="111390" checksum="99BA551F77548547" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTI9</accession>
    <name>A0A9P6JTI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Eukaryotic porin/Tom40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_535099</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTI9"/>
    <dbReference type="OrthoDB" id="7827681at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000012">
        <property type="entry name" value="Voltage-dependent anion-selective channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="293" mass="31174" checksum="F5B4C587D318271F" modified="2023-09-13" version="1">MSLPQPVPPSWKDLGKSSNDLLSKDYHYHGTSLEVKTQTPSNVSFKVQGTRDSKSAIAGDIEGKWTDKVHGLTLTQTWTTANVLRNQVELDNIIAKGLKLDLATSLAPEKGAKTAVVNTVYKQSGLHTRATLDVLRGPIFTADAVLGRDGFLVGAEAAYNVTGGNITRYAAALGYNAPEYAVTIHGLSNFKAFSASYYHRVSRDVEAGAKAVYDTNATHGGVALEVGTKTYLDSSAFVKAKINNSGVIALGYTQSLRPGVKASFGLALDTQKLNDPSPAGPSHKVGVQFVFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUB7</accession>
    <name>A0A9P6JUB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10258608at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056604">
        <property type="entry name" value="GBF1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23325">
        <property type="entry name" value="TPR_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="605"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1527" mass="169173" checksum="9E07B0E0CB5948AA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUH1</accession>
    <name>A0A9P6JUH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">High-temperature-induced dauer-formation protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUH1"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="912" mass="101480" checksum="7D90ABD1F18CD0CE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV20</accession>
    <name>A0A9P6JV20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Chromatin modification-related protein EAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_845754</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV20"/>
    <dbReference type="OrthoDB" id="440324at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="100"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="21392" checksum="C3A8DBC10638420A" modified="2023-09-13" version="1" fragment="single">MAEQPTSEDKARYETLKKELMQALPKKRAIDKQLAQIEVQIHNLEVSYLTETAAHSGGNIIQGFENYLKNQTGGRRRYEIHDHDRIFSHSSLTYQKSLELMGEGEESTATNEDYVKQSTPGPLTTIPIPPAARAQEMTAAQAKKIKDREYQRRKRASMNRSTGESDDEPVSATSGTSRRPTKRARLAADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV72</accession>
    <name>A0A9P6JV72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_757892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV72"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF54">
        <property type="entry name" value="FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="2">
        <location>
            <begin position="95"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="44848" checksum="8C70CDD990E3277C" modified="2023-09-13" version="1">MPTSISEFKSIPNLEYHPDYTNYILRRDQRLAEDPTLPQTALPLGYPKKVGGPIVWEGSDWKNEAQWVYQLSEEELKEIDDGLHYFKRRNLSLGHLERENFPLPSLGPRLYELCQELYSGRGFFVIRTIPIEKYTREDLVIIYVGISSHIGSGRGKQDGTGAVISHIKDLTISHANEKGGIGNSAYTTDKQVFHTDVGDLIALMALDVAQEGGTSRISSTGRVYNELAATRPDLIQTLSEPWVLDTFGGDPPHTVRPLLYHEDERVVIQYSRRHFTGYGKQTRSPDIPPITEAQAEALDAVHFLAEKYSLALNFQKGDIQYINSLGLLHARDAFRDSGKHTRHLIRLWLRNEDLAWKTPFTLKPIWTRLYSAPPDEQRFPLEPEIRRKASGKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW16</accession>
    <name>A0A9P6JW16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6 18">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 18">Alpha-IPM isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 18">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_843439</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 18">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6 18"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW16"/>
    <dbReference type="OrthoDB" id="2279155at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000006">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000007">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000003">
        <property type="entry name" value="3-isopropylmalate dehydratase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012235">
        <property type="entry name" value="3-IsopropMal_deHydtase_ssu/lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002458">
        <property type="entry name" value="PRK01641.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004016">
        <property type="entry name" value="PRK05478.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009116">
        <property type="entry name" value="PRK12466.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF9">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001418">
        <property type="entry name" value="ACN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 18" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="14 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="19">
        <location>
            <begin position="13"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="20">
        <location>
            <begin position="539"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9535081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="760" mass="82188" checksum="068BDC70E263524D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWW9</accession>
    <name>A0A9P6JWW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_901373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWW9"/>
    <dbReference type="OrthoDB" id="3355480at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="58935" checksum="568C3AF87F757AC6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E337</accession>
    <name>A0A9P6E337_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158009">
        <property type="protein sequence ID" value="KAF9521632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E337"/>
    <dbReference type="OrthoDB" id="3069523at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="218" mass="25150" checksum="BAB5D5DF65EC813B" modified="2023-09-13" version="1">MLWVTYVQLPYLCLTLYLQKHPDNRHAIVYELTSPNRTPQHLSHVKYSLRLCSFIGDLYQACLLSRLDTIGCVRILLFNMAMVEHLTGIENILKRAGPKLWKESMYASPSLGATSFASANSCNSPSELCWSILDWEVREFENQIRSARGRVQDNQFLLRDNEHNKIEGGVRRKVDGLIRYAWECCRFLREGYAGDGRYVAVGGWQPSISVDWRHSNFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3B3</accession>
    <name>A0A9P6E3B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157994">
        <property type="protein sequence ID" value="KAF9521741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3B3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="143" mass="15923" checksum="DAD7B3EF7BE2160E" modified="2023-09-13" version="1">MNQGSVNLQSYISLGQSFFIDFWAMLSQCSSCSVPQNCKLSDGTSCDACILLANTGTKITSHKISHVEQDTHRRDAKSKVNGGHDPLAHRLPVELSRFLPQPNRFFDKASTQHPTTFQHLPFVSNIKTDGVAPDIGLLRFRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3Q0</accession>
    <name>A0A9P6E3Q0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxamine 5'-phosphate oxidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_865122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157970">
        <property type="protein sequence ID" value="KAF9521969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3Q0"/>
    <dbReference type="OrthoDB" id="434253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="2">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="28813" checksum="E170FE691B3D88A6" modified="2023-09-13" version="1">MAAPRWKTIVERALLKDSKQNTIQLATLDRDAARFGVDLIPRVRSHVFRRFLSSPNTPSLPLIITSTDIRSAKATQLTEVSHKAELVWWLESTVQQLRIICDVYVVPSPKHPLASKFQELLLESSPSSALSIFRDKDWEADRVDLFRSMSPRMKASWCRPIPGSQLSPNENLKNWPTEIHDPAEGHSEGDKNSPEYEEAQRHWEFALENFATIIIDPLEVDYVDAKMKAIFRKKYSEDRGMIWEEEELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3R9</accession>
    <name>A0A9P6E3R9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157974">
        <property type="protein sequence ID" value="KAF9521923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3R9"/>
    <dbReference type="OrthoDB" id="2670291at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1159" mass="129861" checksum="B2621D836420099B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4D3</accession>
    <name>A0A9P6E4D3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_738721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4D3"/>
    <dbReference type="OrthoDB" id="3267892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="235" mass="25927" checksum="732201727D8BC935" modified="2023-09-13" version="1" fragment="single">QRRRDATSVMAGSFDPRPERDILTSCLNNIGPYLEVEKNEQERQKKKAEKRLREKEKKRKSKEESKAAARRLGKAVAELSGNASMSASIASPSVQGEQVAASSTTKTFTRPTIHIPAMQRSVSITPPSSPRYLASTPGSTPGPSMSSTVSRTSSKRPRTPDDYDSDASIIYADDYEVRPRKRRVAVKKGWKGWVEGSPEPSAKLINLDAVPVLRERRTRSGKNFDAIGVGKEGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4H3</accession>
    <name>A0A9P6E4H3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIGR04076 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4H3"/>
    <dbReference type="OrthoDB" id="2838513at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023811">
        <property type="entry name" value="CHP04076"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04076">
        <property type="entry name" value="TIGR04076 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13535" checksum="3CC61344FB2C1061" modified="2023-09-13" version="1" fragment="single">MADLRNSPPHDAFQLYDLHVEVICPEGERIMCGAKPGDYFTMEGEMFRLPPGQGFSIYSLGAVLPLLAAKQRVTHPNDWMSTDAEVACPDPNCKSKLKITRTGLRTFSHSETTVVPLDNKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5L5</accession>
    <name>A0A9P6E5L5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_70657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5L5"/>
    <dbReference type="OrthoDB" id="2686356at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39603">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39603:SF1">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040487717" evidence="1">
        <location>
            <begin position="23"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="175" mass="18790" checksum="70F6B145E1E6A95B" modified="2023-09-13" version="1">MRIFSTISSVSLVAICIIGISAKQSTYPHVIPGPGLPSLKSLQLTSADLYNRQLITNSSIEKRDEGYDKNCFAFTTADVQSTVACFDYLTRLGHVDCTVPVDNNVFCTAGDAVIGGSKLDQTTGVTSASCWWVALAVQWIFQNCNADGRVGGTAIPINSDQNLIVGVYNTDWVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E669</accession>
    <name>A0A9P6E669_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_775787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E669"/>
    <dbReference type="OrthoDB" id="2638305at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="36825" checksum="72906361BAE6EC60" modified="2023-09-13" version="1" fragment="single">QLVWEANILSYVDYVYEKTKVHGNSSALRVPPNLPKQVPLLGPTFVPPSYRHVMKRSTVPKIVPETAYIVALTVVHPFYHSGTISICPQCGDSKNVNWDSWTGTGGREVQGLYRNERVIGYQLRCKTCQGKPKEERKQGFCFATTNQIFWEKWEHWKIPRSIPIFNKRLAVTRNLYDLIIELRPTSTAAGLAEHIRRNTHPGQLRYNQLHEFSAPDDPSCYNDAPITNDIITDIYLDFTKRFREPESVAYCKTRTAQSLSLDNTFKSASKAVVVDSDGKRTRLFTGGILSVINEVSETMGWVSDSKLNTILSNHMKALLSNSVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E687</accession>
    <name>A0A9P6E687_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_887111</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E687"/>
    <dbReference type="OrthoDB" id="297496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF342">
        <property type="entry name" value="OUTWARD-RECTIFIER POTASSIUM CHANNEL TOK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="10">
        <location>
            <begin position="259"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="10">
        <location>
            <begin position="451"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="625"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="625"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="660"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="726" mass="83823" checksum="B4C68EE196658460" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E743</accession>
    <name>A0A9P6E743_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">KRI1-like family C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_862234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E743"/>
    <dbReference type="OrthoDB" id="10252032at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="3">
        <location>
            <begin position="579"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="767"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="780"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="800" mass="91183" checksum="7E1A52E7ECC23D9C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E755</accession>
    <name>A0A9P6E755_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_910537</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1043025at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038066">
        <property type="term" value="P:p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06626">
        <property type="entry name" value="STKc_MEKK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF32">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1054"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1083"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1397" mass="157945" checksum="904707B73F7F731D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7S4</accession>
    <name>A0A9P6E7S4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Golgi apparatus membrane protein tvp38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_774125</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking and spindle migration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7S4"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051076">
        <property type="entry name" value="Golgi_membrane_TVP38/TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549:SF2">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="12">
        <location>
            <begin position="151"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="328" mass="36471" checksum="C304E241686EE72A" modified="2023-09-13" version="1">MALPGNNTNTDHVYYPPDSTLGVKHPGLDSNSSTSLRAYGESDKPKAEHEPLTREISRTPSPTPSEVEALNPDIKGRLLQFFNPKNWRRYGWYWLAIVLSIVFTVLISVFHEKIVRGLEPAAVWLRDGSKVGWLVPIAILIIISFPPLFGHEIVAALCGLVWGTWIGFGIVAAGTFFGEVANFYAFRYMCRSRAEKIEKKKIFYASLARVVRDGGFWIALVARYSAIPGHFTTAMFATCGMNIFVFSAAAILSLPKQFLNVYLGVLMGESVKNGGTTSKSRVITTVAFIATFVVTSFAMHYLLKKVAMVKPQVIYERRKARYAILSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7V1</accession>
    <name>A0A9P6E7V1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calnexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_871405</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04098">
        <property type="entry name" value="eEF2_C_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04090">
        <property type="entry name" value="EF2_II_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01683">
        <property type="entry name" value="EF2_IV_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04167">
        <property type="entry name" value="Snu114p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000004">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000029">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000009">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000001">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.250.10:FF:000001">
        <property type="entry name" value="Calnexin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000011">
        <property type="entry name" value="Probable calnexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000646">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031950">
        <property type="entry name" value="EFTUD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044121">
        <property type="entry name" value="Snu114_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035655">
        <property type="entry name" value="U5-116kDa_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF6">
        <property type="entry name" value="116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16004">
        <property type="entry name" value="EFTUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1442"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="domain" description="Tr-type G" evidence="18">
        <location>
            <begin position="139"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1190"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1389"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1468"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1202"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1231"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1475"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1497"/>
            <end position="1508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00055641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9524095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1508" mass="167832" checksum="7D0A69132A6CE215" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7X6</accession>
    <name>A0A9P6E7X6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_861801</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7X6"/>
    <dbReference type="OrthoDB" id="3266532at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="321"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="893"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="928"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="973"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1015"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1046"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1114"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="24"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1270" mass="141086" checksum="C2D2A41A8A08E75C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E817</accession>
    <name>A0A9P6E817_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L10e/L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_861768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E817"/>
    <dbReference type="OrthoDB" id="10258869at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018255">
        <property type="entry name" value="Ribosomal_uL16_CS_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_uL16_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003239">
        <property type="entry name" value="PRK04199.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00279">
        <property type="entry name" value="uL16_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01257">
        <property type="entry name" value="RIBOSOMAL_L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="216" mass="25037" checksum="467A7ABFAF2A17F9" modified="2023-09-13" version="1">MGRRPARCYRYCKNKPYPKSRYNRGVPDPKIRIFDLGRKRANVDEFPFCCHLVSDEYEQLSSEALEAARICANKYVTKTSGKDSFHLRVRVHPFHVIRINKMLSCAGADRLQTGMRGAWGKPYGTVARVNIGQIIMSIRCKDSNAPVIIEALRRARYKFPGRQKIIVSKKWGFTNVEKTDYLKLKEDKRVLQDGAYLQFIRPKGNLEQNLRNQLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E834</accession>
    <name>A0A9P6E834_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_774211</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E834"/>
    <dbReference type="OrthoDB" id="28335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000061">
        <property type="entry name" value="TFIID subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="8">
        <location>
            <begin position="201"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="308" mass="31742" checksum="026D64934FED00F4" modified="2023-09-13" version="1">MSTGYDSQPTTPTPAGRGRPKGAGTGAKRGRKPKGAPAANSSVNAGASPRPFITTSFSPTSPAAPSPSFTTSGHQGQNGEGSRVHWGAPGAEGITGPSSAVGNSSNADSATAGSATQAGPVIDPALVALGAAPPAPGTPKLEGLASLSLTGRGSSHPPPGLARPGGEEEGEVDDEALPAMADDDYSAQLSWQSQSKDNLKVLMDNLSPAQYDRFEAYRRHALPKQAVRKVIQQTLGHQVSQPVAQIIAGFSKVFVGEMVEKARAVQARRGEVGPLSPDHLREAYRAYQGESGRVGAARPLRSKKLFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E877</accession>
    <name>A0A9P6E877_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_774337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E877"/>
    <dbReference type="OrthoDB" id="2794314at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="12787" checksum="FDED1DB96243DB85" modified="2023-09-13" version="1" fragment="single">TSEGTSNLVKSLNICLRAQGITRSGNHNDDHPAPPYSPSAHRALIALRSAKSNRPYNSVSDEDYHLEVEMLRAGVSQRLPAPITVSRDVKAIYIEMSKHVAKYFEVLDFYNTLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8J8</accession>
    <name>A0A9P6E8J8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FYVE zinc finger-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_886136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8J8"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164:SF30">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="49"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="153"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="36193" checksum="E5D50E39F2C51E97" modified="2023-09-13" version="1">MDSSASSSSASSVVNVSIIERTNEHLAVLLPKSLWKPDSAAVHCDNFFCRIPFTIFERKHHCRKCGGVYCGACTLRTTPLLDISNLDFITPPRNVPITEFDSPTSPVINSRVCDDCYDQIRGYPTTPRTPEITRPAFRRVLSNPIAMIREQLPNLSAPQSPSSSTSDASELSQSEHLPRSSKRKPNSLRHKPSASSLNTQSSSNSGPSRQAHRLRTSRLPLTEDLERSYGELDAYPLRRSSILCKATGGGRWEPKQDPVYDFYRVPVPGGKAPFEIEMEREEKLEKIRKQNPVVRHGEFQYRTPKEPEPVNISRSLNRLSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E922</accession>
    <name>A0A9P6E922_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_909509</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E922"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050589">
        <property type="entry name" value="Ikaros_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404:SF114">
        <property type="entry name" value="KLUMPFUSS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="175"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9524981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="34965" checksum="438DF52987358199" modified="2023-09-13" version="1">MHGHRASDPVDNVRRDAKDGAYHCPQCDTPFTRRSNLRRHFQIHTRNAVQKCENCEEEFANKQELQQHSSSCYSLTWNPSNDKAFRGLDSTLLTDTASDPTFNTNAGTLNAFLYGANYPSSTSLFPSFDTPETRYGTYGTNEFISPLPSPIGVMPSRTNSSNALDGNLGSLNSSLNTAFAPTRRPSSASSGSLSSSASPSPFSATPNMSQTSFPSVQTSYGWNGLSTSPMDPVDDYAFYSRQQVKEMIDVVSECLIDTMENVITRTGSASLGMFDSVEGQLVQNMRDAGFRQTVISEAMPRVFYRMQTRGNEQKPALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9I6</accession>
    <name>A0A9P6E9I6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_570196</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9I6"/>
    <dbReference type="OrthoDB" id="19448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF58">
        <property type="entry name" value="ALKALINE PROTEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040252224" evidence="6">
        <location>
            <begin position="19"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="8">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="147"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="39853" checksum="910629CE36EBCD3A" modified="2023-09-13" version="1">MHRLNILLVSLLFSVVSASVTPSIRVPIESYTGAKTGLHIVKLKSSSSSRTWTAKLGLKNAAEWENFNSFAAHLNVDDLETLRMSPEVESISEDGIVQTLALITQTNAPWGVARLSSITALSSKDTSMANFNYTYDDSAGGCADIYIVDTGVKLEHHDFGGRATWGYPTTGTQTDANGHGTHCAGTAAGLRYGVAKKARIIAVKVLNDSGSGSVSDIISGLNWIMSNVQKIGRPSVVNMSIGGSANTALDNAVTSMTSAGVHVVVAAGNSNADAGGFSPGRAPSVITVGGTTINDVTMSTSNYGAVVDIWAPGQNIISDWISGLDSTNIISGTSSSAAHVSGLIAYLLCKDGSITPAQMSTKLKGYCIPLSPSDSLFGSQCAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAB4</accession>
    <name>A0A9P6EAB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_521705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAB4"/>
    <dbReference type="OrthoDB" id="2670057at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="53143" checksum="734D3E93B94CC115" modified="2023-09-13" version="1">MVAYPPRQPLLRRQDGPIAAPSVAGLSGVKTVDNPVETSGGLVVDTAAGTGTQSAPPFIPTGGTPKSTSAFTVTPDSPTTSSSPSSVGASSTKQIALSTVVASCVGAFVGATAIVIFSLWMYRRYSRSLKQRAYKSRGPFNHRNGQSNGQRQRSHGEAWNRLEDHESEDKWEGSYQTKEGKDSTGARELTQVAPMEKLTMFKKTPSVRTAYTHKSTDGTDFSFPSSYAEFDPKLADALKSGQHDMPEPKPFLERVDSDPSSYLTVHSRLSGAMSPTQNMAIPTPPPMFSNSHKWESAEVVAFPEAQSVEVLNHNPFEDEDDDEQGRRKSHHNPFFGARDHEISRGRSNSTSSARSRSRSRSRSRNRANSTATTVSLPKISAKAKGKERMRYSAATDHSTPQDPFEDANGDELPRPSFMTHAPTSSTSSMDNSDRERALQSLIAALETPEDEVRDRLRIASMQPSIVSRASSIGVSDVANEFPLPPSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAB6</accession>
    <name>A0A9P6EAB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_859182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAB6"/>
    <dbReference type="OrthoDB" id="366390at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="16428" checksum="8973FFC56475D9B8" modified="2023-09-13" version="1">MEKSSHDESQDKASTLPPDTIAFAHRMFDAAREGDTTLLLSAVDAGLSPNLTNSKGNSLLMLAAYAGHTELTKGLLERGGDPNRINDLGQSMIAGAVFKGHIEVVHALSAKGADPRLGTPNAIQAAHMFGRHDLFKEFGGTEEDKTNVPNPLPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAY9</accession>
    <name>A0A9P6EAY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-Glycosyltransferase/glycogen phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAY9"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 72B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045:SF31">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 76B1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="58748" checksum="1157A1A786BC7FB4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB71</accession>
    <name>A0A9P6EB71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_858463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB71"/>
    <dbReference type="OrthoDB" id="10264728at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20956" checksum="48351A3EA1FA1D06" modified="2023-09-13" version="1">MSITRPFKATDMFKFNNINLDVWTETYGIGFYLSYLSRWPDMCVVEESPSGQLMGYVIAKSEGSGTDWHGHITALTISPPYRRLSLASRLCSFLALISSSTYKNFYIDLYVRCANTIAIGFYEREGYSVYRRVREYYGSLGVGRGGRDEEDAFDMRMPLQRDRERRSVRPGGRDIVVSAEEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB79</accession>
    <name>A0A9P6EB79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_817364</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB79"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF79">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="596" mass="68395" checksum="F169DFB087640E03" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBD7</accession>
    <name>A0A9P6EBD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_771496</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBD7"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="11887" checksum="C37DAD82AA27EFD9" modified="2023-09-13" version="1" fragment="single">KLGAERAKFYMCELIISLSELHKRGILHGDLKPANILVDREGHLVVSDFGLELDFVTRGRRGSPYEMAPEIYLDQWYSFGVDWWASAVVLYWMLTGRVSTPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC41</accession>
    <name>A0A9P6EC41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_870543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC41"/>
    <dbReference type="OrthoDB" id="5336600at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669">
        <property type="entry name" value="5-KETO-D-GLUCONATE 5-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43669:SF4">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="26436" checksum="5830A1E9D97B1F53" modified="2023-09-13" version="1">MPSVSSRPPVAFVIGAGPHIANTVAHMLHEEGYLVALGSRRPSDEAEHMDKFASVVVDAANPSSIRHAFQTVVKEFGHPTVVIFNAASFVTPPDPSDPLSLEAEYFHDAASMGAGVFIAAQEAVDSFRHEAPSPHPKVFIVTGNTIAFEKNPNPEYLCLSIQKSIEAQLIEAFAESYQKENFRFYFASLASKSASVNSAEFMHSAPTHAKVYWDLIAHTTEQGSWDYRFTADGEKYEDEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECJ5</accession>
    <name>A0A9P6ECJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CHD5-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GET1</name>
        <name evidence="11" type="ORF">CPB83DRAFT_938024</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the WRB/GET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECJ5"/>
    <dbReference type="OrthoDB" id="69461at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03113">
        <property type="entry name" value="Get1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028945">
        <property type="entry name" value="Get1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027538">
        <property type="entry name" value="Get1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650:SF1">
        <property type="entry name" value="GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650">
        <property type="entry name" value="TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04420">
        <property type="entry name" value="CHD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040383152" evidence="10">
        <location>
            <begin position="19"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="3"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="169"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="201"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="25787" checksum="0A6E00AAF4D543F6" modified="2023-09-13" version="1">MSLLISIFFLVFLAQLVAWVGKTVLVDIAYGLYLRITRSPLAARQRALKTHILTTKAELMKTSAQDQFAKWAKLRRSVDKGLADLEKLNAEVASAKSGFSMKFNTVLWIMTTGSQFVVGWWFRKQPVFFLPEGWFGPLGWWLALPFAPAGSVSVGVWQMACKRVIVVCERVVKELLGEPSLRQLRIISLTAIVIIAPTSQEGEPEKVAMPGLAPTPNNTPRKEATKEKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECR6</accession>
    <name>A0A9P6ECR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_837154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECR6"/>
    <dbReference type="OrthoDB" id="3258419at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="44102" checksum="6E0EBB398BD720FB" modified="2023-09-13" version="1">MSRIENGKTINRKDFLPQANGSHHTQLVNYNIGQFNALCNKQSNNLKAHLSIFLMLPVIESDKKFGVIPSDHTQSYGGFLAIKTKADSDKDEVDTVLKELDACEADIDQSALLAQLGVDQNSIYLPAAQPASINPGKQKERDTEPTLASVPRTPSSRLGTLIRQGKIYNDNLPAHVQAAKRRAFEIPEIILNKLALPSSQTAISNIIQQDLMRVLSEIVVIKPNVWFSTRPPKIQYDLLRTQPTPPASFLKDLEAEAGKAWLAGAKSIKDHCFNDGADALPLWIKGKSWLESEERRARYTQETMQEIQKAQATLDTLAWRAKLPYCRGDTNSSGLVQYLGTRFLMDNHINIMVEELTKELESDSFVTSGAKLHNLGFLSEIQKFYSTHAAKATTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED87</accession>
    <name>A0A9P6ED87_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_768595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED87"/>
    <dbReference type="OrthoDB" id="3217871at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="327" mass="36807" checksum="924913D9FB24903E" modified="2023-09-13" version="1">MSTSKKRARVDDIDSDNEPAVQAIPPTRSSDFWFSDGSVVLEAESTRFRVHSSMLALHSTVFKGMLQHLKIGKAHHKMIDGCPFIPLDDSEEEVTYMLSALYEKNPRPRPAPFSLFAALLRLGIKYDVKCLRNEAIDILESALPTTLEKYQKLNTKTNGIIDYSSNVLMDVIDLVTETSVLSCLPAAYLILSEDIDSIMYGATREDDTAVVLDEGAKNAIICGRNKLLKDAPFKAFSWVKGSGSACGQKRACMAALHDAMEDLWRNQVQQLTCFETFKKSLLSRFCATCQAEYGKTHRDEQRKMWNDLPTYFGWTSWKDLPNIHSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDM5</accession>
    <name>A0A9P6EDM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_433126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDM5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="65" mass="7544" checksum="83CCED9ED956EBF2" modified="2023-09-13" version="1">MIPRPIRPINHAKCDHPNNRKVFGCPLAPILSRERLSSNREAECLVVTNTTFGLHYPYCYMSHYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE75</accession>
    <name>A0A9P6EE75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Purine-cytosine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_856232</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE75"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9527466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="547" mass="59396" checksum="0CCE9608D0A87DBE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEB3</accession>
    <name>A0A9P6EEB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_768282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEB3"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="15274" checksum="95AE4C717C79CEB5" modified="2023-09-13" version="1">MRPSGPAPPKRAWVLPTAPGPTLRQRIERREREAGLRCDDVSCGLGPSDEDPLSEDVADTIKKVHQLTIRSKDMGENGLRTSLCEHKFHSSCLVSAARVALRDADAVVNDDGSVDVSCPVCRHEGCMMHGEWDDGVKALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEM8</accession>
    <name>A0A9P6EEM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEM8"/>
    <dbReference type="OrthoDB" id="3039774at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="64" mass="6896" checksum="0DB694592DBEAF17" modified="2023-09-13" version="1">MCSSSSTSLVSAVSYSSTPVASRQTTHQTSELCLNYSAPQCCHCGYRGQHADACPFNPNPQIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EES7</accession>
    <name>A0A9P6EES7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0390 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EES7"/>
    <dbReference type="OrthoDB" id="5239630at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019034">
        <property type="entry name" value="UPF0390"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16967">
        <property type="entry name" value="LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16967:SF1">
        <property type="entry name" value="LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09495">
        <property type="entry name" value="DUF2462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="10366" checksum="06C74BC24FE041B3" modified="2023-09-13" version="1">MVQGKTKGLQSKAPSSRQAHKAAANTKKGKRAIAPKKTVLIKQATMHKDLTAKINKSIEKQMVSAASAGKLTIMKNTMPDESASTSALSKFKRKSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFQ0</accession>
    <name>A0A9P6EFQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFQ0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="9775" checksum="D8EEF59751044B84" modified="2023-09-13" version="1">MKYSSVSYCFEAGGRCWPIILFVPLWMSCLRFTGQIRSSRTQRNRAFSLGGCRIFQPDRRSVRRELVLARRCLCHFRANLNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGD1</accession>
    <name>A0A9P6EGD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4470 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGD1"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4470" evidence="2">
        <location>
            <begin position="248"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="997" mass="112456" checksum="F0340EE64FEEC3BB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGW3</accession>
    <name>A0A9P6EGW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_263317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGW3"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034595">
        <property type="entry name" value="NDUFAF8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34561">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34561:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7522" checksum="371403968C732CB2" modified="2023-09-13" version="1">MSPPAISGAKEPLRPLKRLALHTTSTCAAQATKYGKCIAASYLDVSKDMCKEEFAEFRSCVRQAMKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH33</accession>
    <name>A0A9P6EH33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH33"/>
    <dbReference type="OrthoDB" id="3262196at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22935" checksum="B156F5C2ECA0A218" modified="2023-09-13" version="1">MPLSSLLSRTISRRPSPKSHSSFDDIFDNRAHLMKAEKVRKPWPTLEQINELVKRACGQYIFLDTITCFVGAQCLSPVTQLDIVIGCLSDHSLFTDMDSIYRLILEQCPYQDILKVVIDNLVKPGHGAFVSPIAEIWQFSCAQVQLVVDSLAAVVMEDEGGDLKYHHLSFLEFLADEERAGKFFAPPALALERFIGDVKKGEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH80</accession>
    <name>A0A9P6EH80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_289734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH80"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="17412" checksum="C39285F8C3FC0424" modified="2023-09-13" version="1">MPIRSFSSVRPLLPSFLPFPPRSLHAPLLISVRSIHPSTYWIRLTSTLALWPLVLCSVFRLFAYRHVMSTVFASISLSLSLSLSRVSDSRLPLIRSSLNFPRFRFRFISSLSFHSLSSQSTFESFIHSMYSLKYPFPLVIRSLFHRCVLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EII4</accession>
    <name>A0A9P6EII4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EII4"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="25350" checksum="4BC3BA56B1240431" modified="2023-09-13" version="1">MTDQKSLSFGVLLLPGFQILDAVGPVDFINSHSQQFLKFVSLAPSSLVAKAPSIEWHYISHSLEPVQTTSFPVQHPTTTFKECPKLDYLIVPGADSTTPLPEGCAEWLKHIFEKDLGGLLLICVGSLSVARSSNILDGLHVATNKMGLKMMVPTPHYDNLKKVKWVGDKRWVVDGKVWSTGGVTSGIDLAAEFVRRTFDPEVVTLAKNLMEYTGRPDAPDEFAFILDGVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIP6</accession>
    <name>A0A9P6EIP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_882713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIP6"/>
    <dbReference type="OrthoDB" id="2320332at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015075">
        <property type="entry name" value="AtaL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08982">
        <property type="entry name" value="AtaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="13691" checksum="8B90804C15E7B3ED" modified="2023-09-13" version="1">MPKNIASTRPVNRPAASAKLVSEGDKIIRSMTLKDGKLIKENLNIYERMMVYFDAIEATFRVTNMISYDQNNELLLTYSFVNGVPSLLDMGADHTAEEINQIIGGVVDKTVDVIRELVKNGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIY7</accession>
    <name>A0A9P6EIY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_834880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIY7"/>
    <dbReference type="OrthoDB" id="2963154at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="459" mass="52132" checksum="EBE2C3CE0DBEB61A" modified="2023-09-13" version="1">MTTTTTTITQKHSQTTRPDLRSRMSSRRRLPHPNASTSTTPTARESVLQQQHVMLSYSEFLRNFDTIPVSFNGDYRHRPSFAISPFDEVSDGIEPGPSQVHSGFYPQDQQQDFLVESGWMRDEFGNDHYVGHGKIEEVEVEGVGATVHSDDEVEEDFATPRAKITSSLFPSSSVVGGRGDDAGTERGSKRSRKDSLPLTSTPPSGQRLRNLPSHKSLKETTTGSDYQSLKATSTATPHMYPPTNLNNTIQHSTLAHDKEVELVGEILDSIVSSQEDIQFMSTYFLAKSRGLEKELSQHIDLCSRMEESLASLRASMNLRMQMGAEEWDVRSASWYQKTLERLSRMRGTVEAHALRPRPRAAILAKLEQHEAKLADLASKYSVAFDRLRLRHLHFLLTQSHEEAKLHKDMKKSRLLSRASFERRWKEGKTLRETLRVNFSDLQQEFYNNAERHLRHPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ13</accession>
    <name>A0A9P6EJ13_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pali-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_852198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ13"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035838">
        <property type="term" value="C:growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF3">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="26645" checksum="64042AEB2D6164A9" modified="2023-09-13" version="1">MKAVAKPFARYPITAFVSCGFLFATFILLLLVGISLTIIKPIYLVTFRSTTTSGSTLSIATELRFGVWGVCATSGLNPATLLGNPGLCFGPQLGYDVPEYLTNIVGISQDVVKAVEKALLVVLVLHPIAAGISLLAFMTSAFLGSHAFAIFSLILTIITALLTSVVLAIDLALVIVAQNQVKNLQNFHFAVQFGNGVWMILTAVVLVWGAVITLSARACYCMGVRRHPSDFKHKNRHVSDEDLAQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJK6</accession>
    <name>A0A9P6EJK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJK6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="62" mass="7043" checksum="AB245DB5378CB3DD" modified="2023-09-13" version="1">MEAMDQQGTTPDWSFPHQEKPYLVILLIAGVFGSNHVNLPERSESTDMSDYDGHTICSFEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJP8</accession>
    <name>A0A9P6EJP8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJP8"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="128" mass="14098" checksum="22CED803FF101E2E" modified="2023-09-13" version="1">MARYLLAIISTYLGHEITHDDERPRHPGYGLITSCVFFDVEHTHTPTTSTTTLGNQLLILIDVVLQRMMTWESISPPSLALHRYLLILDILLITGSVIIFGSTVSPVQVFGYSIALGGLVLFKTTGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK71</accession>
    <name>A0A9P6EK71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase delta, subunit 4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK71"/>
    <dbReference type="OrthoDB" id="337486at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29532" checksum="5E5BE13D2089FD0E" modified="2023-09-13" version="1">MLQSQLNFSASKRTSSTSGITKSKVVKPALASKVPPRSPRKLKRRTSSGDEETDDYDDIETPEISEEEVDEIKDISPPVEEKERETKTVELPLVEEVQSVTPKTRSQTKKASSSTSSSAAKKNATKVKDVSSTNASPLPFKPSNLKPEDLAKKVEANALKENDVDQVPELDPKSAKWNKEYGAAKAKMGHVPAIHGEEDNKVHEILRVFDNSHEYGPCVGMTRLERWERADALGLNPPKEIYEILNTKQGLNLDEYKHTVFHKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKU3</accession>
    <name>A0A9P6EKU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKU3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="20015" checksum="8889ABA3CCB4769F" modified="2023-09-13" version="1">MPPSKAAPARKPAAERAPKKANEKSNDECSHQKVPVRRRRRNSNPKKEIIGPQKTSSKVARKPTKATVGPSTPKLQQVRNTSTTSFTIKVKPLFSVQKQNAAIWHSKSSKTDLALFSPTDADDEVEERQKQQRFEQTAGCQSSKAKRRDSDLLPTVDVAADYISSDSPRYFSNHCDCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELB7</accession>
    <name>A0A9P6ELB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_834059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELB7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="17790" checksum="C4869DC5AE302726" modified="2023-09-13" version="1">MSPWTSSFHSAVVLSRRGSVFCLDYHYIWFDMRYNQISVISCGILTQKIIVAQLPKTMYLQASQGQALWETSEAVSQTPGTTFNLPRFKLGTSAATEYILTLDWTTLIWLSQLKRVTGAMWNHKAGRLFLIMSRQNFKFKQVKHFNSLAPNQAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELD7</accession>
    <name>A0A9P6ELD7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="8">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_849550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="8"/>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELD7"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0697">Rotamase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="421" mass="46353" checksum="B3CF484F24A603B1" modified="2023-09-13" version="1">MFDFKPPKKQILTQPQLDAFQASSTHKAIVTYIETLNESVVGVKLSDKCEPLSEGVKSVLKILENVEQIAKDTPAVDNSGSRFGNPAFRVFYDKVQEVSPTLHTSLSGLPVGAIPELTAYFTESWGNRTRIDYGSGMELNFLCWLYCLEKVGVFAPTDHKAIVIQIFWRYITLMRLLQSTYWLEPAGSHGVWGLDDYHFLPFLFGSAQLRDHKYIKPKAIHDQEVVEEYAKEYMYFACIEWVNKIKTASLRWHSPMLDDISAVKSWSKVNSGMLKMYLAEVLGKLPVIQHFLFGSIFPYDGPIVPRAEVSNGLDHTGHAHDHSMDLGGAGQQEVGWGDCCGIPVPSVFGAVAASSGPVPSSTSNIAGRGGIAVESGNLKDLRASRPDVPLGTFEKTSMAGIEGGLQKLKLSGPGIRPVPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELM4</accession>
    <name>A0A9P6ELM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_786620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELM4"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="296" mass="33745" checksum="DDEEC8CEF221DF9D" modified="2023-09-13" version="1">MTDWNSIQELTKDVNAIYKMAYVLLGLYTWEWWTSLELELDLLAGRKNFKWPMLFYFPCRYLPFLYLGSFLSQAEGTRHPVQCGAIYGITLFSGIGSAAFASFNLSLRTLALWQNNGYMKILVFAVFLGRWSLVGVLAPYSFNATWTKGVGCIQGKPNLRGNIILHIYTFVFDLLFFGLAVYKIIGDGTTKISFPPRRQEQTGRVAYVLFNQGISYFTITSILNLISVVFYIINLNMAMAVVVAFPTNFIIPLLACRMVRGLAFFNREKEDIGFSSPNRRWPRQHAQLSSIRFGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM83</accession>
    <name>A0A9P6EM83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_833315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM83"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="224" mass="25412" checksum="F0E25D59DECA6B34" modified="2023-09-13" version="1">MTSSQGLASGRDFCGHPLCLRTSCNNLPYYPLRIYCANAARGPMNWLGRIVDGGFRLLDDNLLCHLINPTDAEFLLFKPGSKPQEWIPFDPATRITWEEGCIVILRDTKYPWIHCFGLSQLVAQVRQSFDPDCEGDTSGSESSEAEYPTIPETITFAKIDLTDSVDSGIDPKPKEEEERAEHDEEDDNDYMESMEVEDCEMTTEHFEVDNDPSLVEEVDWITDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN80</accession>
    <name>A0A9P6EN80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_848576</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN80"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="65"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="69"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32501" checksum="833CFF6C2324B2D3" modified="2023-09-13" version="1">MSTTYDSNAFQPLGWTDKDGQDGLYQPVENLNGVPPTHVALEGQLSDDILAAGRWLKVDASHTQSTNICKICFEEVTFSADLNPCECGYTYCTSCLSTYVSGKLQRKEWPFWCPMNTHRLVLTMAVIKSLELSDAHRKQLIGVVDTPPIVRQNHITTITCPSCNTTARNSGPNDAKDVFLTCSWDHCGYRWCKNCGEKVVLSRSRSGVKVNHRCFASFHELVRRNGWRPCPGCGVIVEKIEGCDHITCTTTGCSVHFCWRCGQAVSTHVAHSACNRPVYVYPGPKTGSKCSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENA9</accession>
    <name>A0A9P6ENA9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_806557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENA9"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12374">
        <property type="entry name" value="RRM_UHM_SPF45_PUF60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000382">
        <property type="entry name" value="G-patch domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="9">
        <location>
            <begin position="472"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="567"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="228"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="666" mass="71095" checksum="859F72E221558339" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENE9</accession>
    <name>A0A9P6ENE9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENE9"/>
    <dbReference type="OrthoDB" id="1938591at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="2">
        <location>
            <begin position="152"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="916" mass="100679" checksum="0E7BBBFCC9365238" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENL9</accession>
    <name>A0A9P6ENL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable quinone oxidoreductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">NADPH:quinone reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_57219</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENL9"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000053">
        <property type="entry name" value="Quinone oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="16"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="36348" checksum="F11835BBDEB0B002" modified="2023-09-13" version="1">MTLPSTVEVITISKPGGVEVIEKTIQPFPLVNASDVVIKYLGVNFIDTYYRQGLYKMPSFPAGIGQEMSGIIIALPTDESILNNETYKRKGLKVGSKVVVDIRGAHATYAAISWALVSPVPESVSTRIAAAGYLQGTTVCAFVEEAYKVKPGDTILVHTIAGGVGLQFAQIGKHIGVTVIGTTSTPEKAKLAKENGAAHVILYNQEDVVKRVLDLTNGEGVDAIFDGVGKDTFLKNFEMIKRKGTIVSYGNASGAVEPFSILKLAEKNVKLLRPKIGNYAHTPEEILHYSQILFDLIEKEILSVRVFKEYPFTGDGVKAAHIDLTGGKTSGKLIIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPR0</accession>
    <name>A0A9P6EPR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_890251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPR0"/>
    <dbReference type="OrthoDB" id="2987506at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="26683" checksum="DE0703CBBABCF469" modified="2023-09-13" version="1">MALNQILVNIQEKALEDLLKNGSKLCMAKAVIDSHGEEVYNVVAYANVNAAISRNNTITYVNAYSMLGTTQTFEQGKTVLTNSTKALPIQFEQAYSLPKRTKAFVGFSPDAPWDGFAFLNSVDASVVLSLASGPTRTYMEEGTLNCPIFISPETEKPGKIHVTPSNKVALWFQPDLKAATMISLSMRNVHVVDLTRFTNVVITYTDDGEWIDRFGSRSGPIDYTKVFAASIAETTNKAANVVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPV7</accession>
    <name>A0A9P6EPV7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_889616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPV7"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188">
        <property type="entry name" value="DNAJ PROTEIN P58IPK HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="45112" checksum="155C6D90AA5E74D0" modified="2023-09-13" version="1">MGRTRTKKKVHTKATDPQVQHVSELKEPSSQALLEKAQDLIVQCDYELALKFVKRILKKDENNVEAKEMLGVALLETGEIDAAKQAFQSLVPPHPGAPVATPPSAHLYLAQLSDDEPNVALQHYQAAVNVLLAQLKGKVRAKDQTPKNDETEIKSNIVRALIGQVEIWMDPSYDLWCLFFDLSFMCASALKQSSSSFEHQAEKTCEDLLSQALQTDPGNAEALQMLASVRLSQQKPEDAKQYLEQAWSVWKDLELDDPKLPPIPNRLALVKLFIELSLYTPALLVLHGVMLTDDQEVEAWYLEGWCFYLMAEQAKENGGTLDELTWQELAKDARDCLETCQVLHRNQEHPDTPLLGHVGELISKLDALGIKASPQDEVEGGDDDDEWESDDESVDEDGDVEMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQJ1</accession>
    <name>A0A9P6EQJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">OMP decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Uridine 5'-monophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_756127</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQJ1"/>
    <dbReference type="OrthoDB" id="10263753at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000114">
        <property type="entry name" value="Decarboxylase,orotidine phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF9">
        <property type="entry name" value="URIDINE 5'-MONOPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="12">
        <location>
            <begin position="35"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="10">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="10">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="10">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="275" mass="29852" checksum="81FCB3C799987745" modified="2023-09-13" version="1">MSPGVQTRSYGQRARNAKNPAAKTLLDTMERKKTNLAVSVDVTKSEDLLAIIDAVGPYVCLIKTHIDIVEDFDSTLIAKLQNLERKHDFIYFEDRKFADIGNTVALQYSSGVYKIASWSHITNAHVVPGPSIIKGLASIGLPLGRGLLLLAEMSTAGSLATGSYTEAAVELARQNQDFVIGFIAQRRMEGLGAGPEEASDEDFLILTPGIGLESQGDSMGQQYRTPRTAVLESGSDIIIVGRGIYGSDPKAIDAISGKARRYMEEGWKAYVERLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQV8</accession>
    <name>A0A9P6EQV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_938985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQV8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="28190" checksum="9776F54EFAA8FA2A" modified="2023-09-13" version="1">MFYPFYSFINNYIKQAPKMSASTSNDDSNQTLQRTLLAKMNQLMAATASKQGLDVHAIPTGLNRGTGTRDFTFRLSDIPGDDNTFKRAVEAISARWWRGMGSILESFDEGWDQLEDRMVINGVKPFANDPSAQYYLLPSKNTGVQTALRLYSGNLESVAYFNLDYVHFVPGQGLPKQTLEPIPQVIPSSHHLFIRDPNGDKEEVFPISIIAETGFSYATAEAKERRKLREGEDCYFVAEGLIYIHEREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERH8</accession>
    <name>A0A9P6ERH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERH8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="31744" checksum="528DEE775AAA94D5" modified="2023-09-13" version="1">MNQGDDTEDAWFFNDKKLKELHWAPIDAYCTSELEEYLLKKRKKSTAASTSPAVVADNGLWPTQQLQNVDWHPYDAAAACWYKKKEQSGQDDSNENKAEKIQGIQEATTHSNSDDEPIGYAPLKPGRLMDHQGDEQEGLHSYLLGKHYKVGEMTPLGVVLVENTQDTNLDEPEHHACGSQSDRQQGLRNDLLGKHYKVGEMTPLGVVLVENTQDTNPGEQPHKAHVSQHQPNSLKPLTQPVSAQELNLQDNMFAEEVPDSQPPVDLRNSLFLCLELLNRREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET93</accession>
    <name>A0A9P6ET93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_901892</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="8">
        <location>
            <begin position="10"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="7">
        <location>
            <begin position="738"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="6">
        <location>
            <begin position="1107"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1026"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1437"/>
            <end position="2063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1440"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1461"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1498"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1521"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1569"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1627"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1650"/>
            <end position="1662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1667"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1688"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1713"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1815"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1855"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1935"/>
            <end position="1944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1966"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1991"/>
            <end position="2011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2054"/>
            <end position="2063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2063" mass="229875" checksum="4108CECD07589DD5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETN1</accession>
    <name>A0A9P6ETN1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_842695</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Vacuole membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETN1"/>
    <dbReference type="OrthoDB" id="42657at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032974">
        <property type="term" value="P:amino acid transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17483">
        <property type="entry name" value="MFS_Atg22_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044738">
        <property type="entry name" value="Atg22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF4">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="550" mass="61468" checksum="F00536508B33DA8B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETN8</accession>
    <name>A0A9P6ETN8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_866318</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETN8"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000053">
        <property type="entry name" value="BZIP transcription factor AtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021755">
        <property type="entry name" value="TF_Aft1_HRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11786">
        <property type="entry name" value="Aft1_HRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="381"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="262"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="473"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9535071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="499" mass="51734" checksum="2BA00A8702DA013E" modified="2023-09-13" version="1">MEYNPATSATRPTTRQTRSDFYLEPNPFEESFKTPSNVRNSSPQNNDSNSSSDSTDKPSQADDDSVTPQSRTSSAKARSTSPSRPVLPPLASLASSTDTSFTWGYNTGSLNSLRSGPLSPAMLAGPQAASEVSAATATTTTHLGFDPNSFRTGLTPRTGLTPRTGLTPGTGLTPLVGAFPPSPNTAAFMAMMNGNGTAASGPTITPNTLNAITSVLNGSTSFNPSTSPTATNSESANYMPSASSAASSHANGLFLLSQAHQELTKREEAQARANNSAATSPANTTNTATTTTNGSSAAAGPKRGSKRKSYDMDPPPPAPPAPTRGGGGGKRTRSNAKQVRGVSEDMEDDMDDSDDNVDDGDMDTAPASGNRRGTKKPETEEEKRRNFLERNRQAALKCRQRKKAWLSQLQAKVEYLSQENERLTAALISSRDEISRLSALVGGAGVVGQVPMTVNGAAGPSAQPVSMNMSISQKTPGGANGTAAVVSGPGGGRSSGYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU79</accession>
    <name>A0A9P6EU79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_843555</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU79"/>
    <dbReference type="OrthoDB" id="21060at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08045">
        <property type="entry name" value="HFD_TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045144">
        <property type="entry name" value="TAF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138:SF14">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="10">
        <location>
            <begin position="123"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="282"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="456"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="521" mass="53171" checksum="C2CBEBFFCF80B396" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUV3</accession>
    <name>A0A9P6EUV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_879329</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUV3"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000010">
        <property type="entry name" value="Proteasome subunit beta type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="26106" checksum="E5E454327D47A5CF" modified="2023-09-13" version="1">MERIDFDRLKTGEVNLGTSIMAVQFKDGVVIGADSRTTTGSYIANRVTDKLTHVHDRIYCCRSGSAADTQAVADIVHRFLQSEAQEREETPTVHIAASVFQKICYGNKDALSAGIIVAGWDKDVGPSVYNIPLGGGLFRQPWAIGGSGSTYVYGYCDATFKDGWGRDETVEFVKNTLALAMSRDGSSGGVIRMCVITEDSVQRLFVPGNELPRFWEGQEVLGAASKKIGSDVEVVPMAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHV5</accession>
    <name>A0A9P6JHV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158023">
        <property type="protein sequence ID" value="KAF9521570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHV5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="34975" checksum="D532C5429A661ADF" modified="2023-09-13" version="1">MAGQIPDLGGGVQLNPSQLAWGSNPAPPISELKKFWIASEAQTATGPDDSQTQPSMAAIWRAKMNRLNNTATQATTSAGPIPGKNIPTTVVPPPELTNIEHTHDMLIDKTPQPIPPIQEQANAQNMQVDSIDLDAAPTLPANKSESLLEWVFLLISQRDKLLKDTLAELEDSPQQRSTTSNFTDADLDKLYSLIKSNSEHQSREAVLAKVYKAQQEATLVARREAAHSILKASASTSQLTQLSHSLMPSNSLPTQSAASLDPVTVESGASSHFSLVSTHKTNSSTERPARLRGGQTKFAAAWHRTQTSALHTAAERYVQHPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI06</accession>
    <name>A0A9P6JI06_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_900326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157993">
        <property type="protein sequence ID" value="KAF9521748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI06"/>
    <dbReference type="OrthoDB" id="3263055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="176"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="37003" checksum="82AAA3D13661D4F7" modified="2023-09-13" version="1">MTLIDVVSPYCPASSAVSLSLYVLKINLEPVRELVLLVQIATYTFAQRTKQDPVGVRSLVYALALIELLHEILVCSSAYIYAVTQLHTDDKFQYVSRITIIEIPLNGIVIFIVQGFLIYRVWCFRTLKWLVFLDASLSVCQVAIVIVFTVKAAPASMYLGLGHLKWLSIALAVLTTTSDLCIVVTQTAVFYRIGAFDLHRSKLVMQRIVLLSMITGLLPGLCALGFLLSVIICPNTFVHIAFFSCITGLYGNVMMLTLNTRDYLRDCDLASDNLSMPDFASVTTPKPETGIGSLTSLRVVSSNSLLDPGDQKLESSASGQAEFEGLSYPEPCHVISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI74</accession>
    <name>A0A9P6JI74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">C3HC zinc finger-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_865040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI74"/>
    <dbReference type="OrthoDB" id="2592092at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013909">
        <property type="entry name" value="NuBaID_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08600">
        <property type="entry name" value="NuBaID_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3HC-type" evidence="7">
        <location>
            <begin position="129"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="NuBaID C-terminal" evidence="8">
        <location>
            <begin position="393"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="422"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="604" mass="64830" checksum="696EEAEAC7E4117A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIT6</accession>
    <name>A0A9P6JIT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_800710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIT6"/>
    <dbReference type="OrthoDB" id="2730619at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043750">
        <property type="entry name" value="DUF5695"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18951">
        <property type="entry name" value="DUF5695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040383168" evidence="1">
        <location>
            <begin position="21"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="901" mass="97502" checksum="4FAD4FA869FE27E1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJL7</accession>
    <name>A0A9P6JJL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_822189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJL7"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF3">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040217074" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="33"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="42517" checksum="53640D5A1952D7CD" modified="2023-09-13" version="1">MIVLSFLAVGLALPFVRATIRFGCAQLVTERFDPLVTPGQVSPHVHQIIGGNAFNLTMKQDADLPNISTCTTCRFKEDKSNYWTAVLYFKHPNGSFLRVPQIPNHYVGGTRGGMTVYYIPGYPPYQKVTAFPKGFRMISGNPMLRNKPESYVDSVESWALSFRCWEDDEWLGASNRYAPGVGQYDTVHLPNKTCGGGIRQNVFFPTCWDGKNLDTPDHHSHMAYVEGKADPSIGLFFQRGDCPASHPIKMPTILFETWWDTRPFNDMWPEDGSQPFVLSMGDPTGYGLHGDYVFGWEGDSLQRAMDHCLDDFGTPELCKELTVLSDEEINQCAQPPQVNEQVDGENLTALPGCNPVQYGPGSATMVKGCTAISTISLPTATPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKA1</accession>
    <name>A0A9P6JKA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PinX1-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_798570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKA1"/>
    <dbReference type="OrthoDB" id="29523at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF31">
        <property type="entry name" value="PROTEIN PXR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="360"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="468" mass="51630" checksum="7015BB603A097860" modified="2023-09-13" version="1">MGLSGKKVKQRIPNDPRNLSWADDAARFGSNYLSKFGWDASKGLGTAGEGRTTHIKVAQKLDMMGIGAAHQRDPNGIAWKQNRDFENVLRRLNNAELGDAVDTDVKIGGFHRARDDFPAEEPTKGVKEKKRKHKDEGEDASEDQEGGKQKKRKSKKQKADDKAMQSNSGSDPLPSKEKEIAVVEVSGVSAMEVKTTKPTFLPRHRSHRARAIAAKNMSSKSASHISEILGIAPTPSASGSATPQEGKLTSLVDEDVLRLEKITTSTKSVADYFKEKLKNRANSSASTPSTLVMNSDEEAVRRGIGSAPSTSADPYEDDEKPRFGLGASRLRFETPKDIDNAQRIGLSQLSKLTSSAFLTGTTTMTVPSPQMTLMAEESGTDEQEPEPTERRRKDKKRSVAVGEANEESIKRKRKSNRKDKTTPKDIEDEPQPDTMGVGADSERSTREEERRKKDKKKKKKKKRKGQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKU4</accession>
    <name>A0A9P6JKU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKU4"/>
    <dbReference type="OrthoDB" id="2678913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF3">
        <property type="entry name" value="P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="477" mass="53343" checksum="8E848CC0D1C959A4" modified="2023-09-13" version="1" fragment="single">MCSPHMSTRSSIQPMPHQEANTLPRLSFFHQSTSLPSLGHSLSTSTLLTHLNTDTDLSQNQPIQQHYAIQVPKTPSIARVSMTNFRNLSSETTRGSHTSSKRFNAPLPTRNSVQGRPYPPHLPLKFSILRPHCPAQDRLAVWKPLQSRRSFSNSPSLIIDREDSARISMVIEARWDKSTRETYGSGLLTFHSWCDSRNVPELERCPVSHITLITFIASCSGSYSASALRNMVHGIHVWHTLHGQPWSVVRSELDAVLGGGGKLAPISSKKAPRPPVTVEIIKAVYQKLNLNTPLDAAVYACLTTIFWSTSRVGEFTLPSLKSFDSQLHIKRSNIRQGFDRNNLQVTIFHLPHTKCSPTGEDVYWASQSGVADPNAALNNHLLLNNPSNEEFLFSYSSNSGCHPLTRNCFLTRINNALSSSNLPPIQGIPFDVVKSLGRWSSEAFTKYLREHAIVIAPYIQDSAFQERFLQYTMPPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL01</accession>
    <name>A0A9P6JL01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Aspartic peptidase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_838972</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL01"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000060">
        <property type="entry name" value="Aspartic-type endopeptidase ctsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000008">
        <property type="entry name" value="Cathepsin D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF75">
        <property type="entry name" value="ENDOPEPTIDASE (CTSD), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040179025" evidence="11">
        <location>
            <begin position="21"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="12">
        <location>
            <begin position="170"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="413"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="52161" checksum="BEDBDFEE3B173EC8" modified="2023-09-13" version="1">MQLTLALSILLAQVFLAVNASPLLRRNSKLLSLPLRRYEHATDLPAQLKLQQHINRGLHRLARMTGGEVPSRRELEENLERRVLAVEGPEGFERRFNRRAPIDESDEVDLEKRYNRIGVPKPASPQGNTLAAVKGGKGQAAVQKTPVAAANAPTADNSLGLDIQAQDTSYLATIQIGTPPRDFSILMDSGSADFWVGSEACQSQNGGGCGNHLFLGTQSSSSFVDSGDQFQVTYGTGAVQGTIIQDDISIAGLALKGHTFGVADVESQQFSSNAVPFDGLMGLAQSTLSEQQTLTPPEALTKAGLTQSSVVAYKISRLEDNKNDGEITFGGLDATKFDLKTLTTVPNVSKKGFWEANLDAVTVDGQDLALQGRTAILDTGTTLAVLPENDAIAIHKLIPGAQSDGQGGFTVPCNSKTVVALIFGGRSFAIDPRDIAFQPLNPRDPTGDCVSGIASGSVGGANEWLVGDTFLKNAYFVTDVEKNTVALAQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMX2</accession>
    <name>A0A9P6JMX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMX2"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF40">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="44145" checksum="799A64D0419261AF" modified="2023-09-13" version="1">MREKSSNYLPVYEGMPRFEESSPPATLTSTSAVEAFLAGTPFECRSVTQFTGGNINYVYRLHLATPIGDIKTVVLKHAQPFFRVCEEVVWELDRQAFEVEAMTRVRKGLPATSTVTVPEIFHFDAKNHFIILEDCGSDVATLKELIISGSLSSTAAETIGSAVGEFIATLHEWSRSNPDGILDVFDECPHTRKMVASGAYDHVVSTLQGTDEDNLPLLSGFEIDSSKLQTIQTLADEYRAHLMSPGHSTHDVFLMGDLTYTNVLVSNDDKQPLRIYLLDWELARTGLPGSEFGMFCAFLSPLTRGDSKAAGLASTVQKSFFNSYSRHAKLNSRLAQDALAHWGANYIYWMPREPLCEEKEVVDFVKEGVEYMARSRDVEFLAQSPVQVLLGDERYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQM0</accession>
    <name>A0A9P6JQM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQM0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="11813" checksum="A19846F3C61055AD" modified="2023-09-13" version="1">MSTSQETLINSSSTFSPLNITPPRRISRERQLALSRTPSPSLDHHFEVSGVNETQPGQYRWTEQEHVHLEAPRWVMLLLRLTGRLLEKIPGVRVKFHSTRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQN0</accession>
    <name>A0A9P6JQN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_853669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQN0"/>
    <dbReference type="OrthoDB" id="3229610at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="31"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="38807" checksum="B9DCC3D4DA1A6E0E" modified="2023-09-13" version="1">MLKADGLPSGFDPWTIACFILYLIAILVTLLRLGHRAYRRQLYWDDFWALVALVSAVIDMVIMLVVSTIRLQDMTSTSHSFVLWITIFAHPFEVWCSRMSITLSMFRVLLPGRKRTLAKTSCYLMSCFATTICLQKIWSCSGMTAPAIPWCTFTSLTPALSLSLNTLADIFLIVWPALMLTEMKLNKTHRWFLIACFSTSVFVMVIDCLYSAYFLKGDLTTTVLLGHIEIVITLLFCNTTVLATYLYRQYSNSNTCGDSGYALPISDFHAANASNATSNLRLGNPRNLPQKQDQSVVLDTVEFSKISEGSLYLEHGQISSKTAHSTNLKEQKFERALSEKDSGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQU8</accession>
    <name>A0A9P6JQU8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isoleucine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_852878</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQU8"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000044">
        <property type="entry name" value="Isoleucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000004">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000023">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000050">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="14">
        <location>
            <begin position="21"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="15">
        <location>
            <begin position="698"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9529218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1078" mass="123781" checksum="585E06E30C610846" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR58</accession>
    <name>A0A9P6JR58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR58"/>
    <dbReference type="OrthoDB" id="3120290at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="43412" checksum="5FA2C9845CFBDCDE" modified="2023-09-13" version="1">MPPSRSSSSTRKSQRFSPLPSTPSPSSPQSSSAASTPTKYSTLPIPFLLWKQDTELFGLKKAEARQLNNRRVAEAIRRLIEPPPVSVSPHHQGHQVLPPRICVGHENYLLIGKWMVRCSGSATLCTRATKYYGDAFPDEILFDHPDLTPFLLMREELRPTPRSTMELRSARFLQPRRLSNSPLYAAAVEKFYVLPNAESSNLPTTPCGTGLRLSATPDAPPSAQPHAELKTPLPGLVHLGTIEISSDEEDGITMLPNPFSSTEIIDVDSVSESELGWDASLAFLLVFWNQKNSRFTEVVLNAPRGRSFCFQQFEAELNFKSISSAKRIELYDPPTGSWVPIDWSQPVGPVTLQGNAFLVRYEGIVAGDLLGFERAVAWAETSGRLAGVKGKGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRI3</accession>
    <name>A0A9P6JRI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_905882</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRI3"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF2">
        <property type="entry name" value="CHY-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="14205" checksum="188AC0969E490E01" modified="2023-09-13" version="1">MCKHILNAQVSIRAPCCKLWFDCPECHAEGQSHNLKKTTEMAFLCKKCKKAFRKDMTVYEDSDEYCPHCDNHYVLEAKTPHAVVGVQGEDARVDARMLKDDRVQQAVHKSAFELDDDDFLDKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRL7</accession>
    <name>A0A9P6JRL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_811551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRL7"/>
    <dbReference type="OrthoDB" id="2338662at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040354406" evidence="1">
        <location>
            <begin position="21"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="558" mass="60472" checksum="628D18FE6A8B8D90" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRX9</accession>
    <name>A0A9P6JRX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_892360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRX9"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="2">
        <location>
            <begin position="37"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="11662" checksum="CC55545B6007EF75" modified="2023-09-13" version="1">MSLVQRHSLQSQTSARSKSLSLQTARTLTSQITDPLFTVVGATSAQGASTIRALQASTKAYHVLAITRDPSKSSSKELEDFGCKLVQADIEPALVQQRLFLDPTTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS04</accession>
    <name>A0A9P6JS04_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_761318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS04"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="1"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="424" mass="46656" checksum="9ACCDF70D3EE3F86" modified="2023-09-13" version="1" fragment="single">LYLNVIRPANISGKKSLPVIFWIYGGGFASGDSAANPGDSFVTRALANNKPVIFVSANYRLNVFGFLGGKEVQEAGLANLGLHDQQFALKWIQEHISEFGGDPRKVTIWGQSAGATSVSLHLLANEGNTEGLFVGGIMNSGSPYHLTDTASRQQWFDFIAQEVNCASAHDRLQCLRDAPYQLLVNAVNKTPALLDYQSINLVWRPTVDGKFIIRDPVLSIQQEKYAKIPIMTGDTEDEGTLFVLSSLNVTNSAILCTYHHSSFFPHARDSDLKLLAQKYSDNPAEGSPFNTGTDNVKSPESKRLTAVLGDLLFQAPRRFFLRYTSRTQATYGSVPLPGLGIYHGFDLPEFFGVGSTPDFEGTDSINSKLCSILWPKWSSSSPQLLTFVDADPGLNITADTYRQDAMDVINRLWLNEVFSTQQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS45</accession>
    <name>A0A9P6JS45_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_850468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS45"/>
    <dbReference type="OrthoDB" id="3184970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29487" checksum="9AEBA19E17F2E9D1" modified="2023-09-13" version="1">MSSTESHTFNDPTADITFASCDGVLFKMHKKHLEITTGGFPSFDKLVVDSDPVPLPESAAVLDVLFRFIRPPLDSERNCQPDLSDLDHLLFFSVAEAAEKYMVYGAMNTSMIHMLHTTESNPLEILNHAAKHGYSKLSNKAAALSLSQTDLLLAQKLTHPGVLNRFLIYRAQWTSVKASALQQISVFIASGHQNCAQIQDLRARYLEQTNARPQSGAEIPNPDDSLTCGRNRNRVNGNQTGCQLPLTFLNMLKAQAQALKAFSEVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSI5</accession>
    <name>A0A9P6JSI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSI5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040263800" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="21152" checksum="0BC1B3DDA49FC4C5" modified="2023-09-13" version="1">MLSKASLAILAVAVAQVSASAIQPLLQRRSLEILYNRQSTCDSICSPFETAVNTCTTTACLCTAANTKSLQGCINCAVAASAAAIDDANTLATTYNQACGASAAGAVTVPAGGGATTTAGGAGGGTGGTTARPSVVTTPTAGTATGGAGAGTTSRAVVTVTSNPGVVPTLTQTVVKPTGSGSSDPSTSGGGDVPGGLAGGALRDVAHKGVVMVIGAIVGGALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSV9</accession>
    <name>A0A9P6JSV9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_892203</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSV9"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040329852" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="39626" checksum="547D5430F8A37CA5" modified="2023-09-13" version="1">MFRYPILFSILLLINILPTIFAHPFDNTYNGRESFVRCEHILQRKEWRSLNTAEKKDYINAVKCLQSTPVNEPSVPAADTLFDLFQGFHIQIALKVHFVGQFLMWHRYFLKLYENALRDRCNYKGAHPYWDWSKDVEEGRNISSSPMWDVETGFGGNGVEGTYTPPTDPDVLANGRINPDAFVGCVQDGPFADLTLNMGPGLSVTKHCLTRHFNESTHQYLNHTAVEEIMAYETFEDLHTQLEGNKGIRGPHGSGHSAVGGEMSNFFSSPGDPMFYMHHANLDRLWRVWQLKFDKKRMWEVGGLTGLEANSTALTLDYILEMNPALGPSVSVRDVMDTEMAPNCYTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSW4</accession>
    <name>A0A9P6JSW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSW4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="13174" checksum="5DAB8DA5BFF9675A" modified="2023-09-13" version="1">MAEDRTSSSIDLGARQLVTWLSYRLVVIILLSIRQGVINRNRVIRFRPEQLRRNNDVERTCYGAHDQAMSHTDYMGNETHQAGVHRNVNLNRVLSELSLSNSAANLNRCRESAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT86</accession>
    <name>A0A9P6JT86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_848829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT86"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="217"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="632" mass="70447" checksum="7F1F01AF2EBC8492" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTH6</accession>
    <name>A0A9P6JTH6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="5 16">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_847756</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="5 16"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTH6"/>
    <dbReference type="OrthoDB" id="275353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000005">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000032">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000031">
        <property type="entry name" value="Phosphoglycerate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF0">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 16 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="24"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>(2R)-3-phosphoglycerate</name>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="63"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>(2R)-3-phosphoglycerate</name>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>(2R)-3-phosphoglycerate</name>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="372"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9532381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="44920" checksum="55FA7A695ACD8C94" modified="2023-09-13" version="1">MSLSNKLSITDLELKGKRVLIRVDFNVPIQDGKITNPARIVAALPTIKYALEHGARSVILMSHLGRPDGKVIEKYSLKPVAAELKSQLGKEVTFLNDCVGTEVEKAVNDAPEGSIILLENLRFHIEEEGSVKNKDGTKTKADQADVTKFREGLTKLGDVYINDAFGTAHRAHSSMVGVKLPQRAAGFLVKKELEYFAKALENPERPFLAILGGAKVSDKIQLIENMLDKVNSLIICGGMAFTFKKTLENVSIGDSLFDEPGSQKVAALVEKAKKNNVKIVFPVDYVTADKFDKNANVGHATDLEGIPAHWMGLDAGPKSRELYKQTVLESKTILWNGPPGVFEFPAFAEGSKALLDATIEAVEKGATVIVGGGDTATVVANYGKDDKLSHVSTGGGASLELLEGKNLPGVAELSQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTN6</accession>
    <name>A0A9P6JTN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">24 kDa ras-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_628631</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTN6"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04138">
        <property type="entry name" value="H_N_K_Ras_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000080">
        <property type="entry name" value="Ras-like GTPase Ras1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="23950" checksum="A95CCF3D7B11DF66" modified="2023-09-13" version="1">MAARAQFLREYKLVVVGGGGVGKSALTIQFIQSHFVDEYDPTIEDSYRKQCVIDEEVALLDVLDTAGQEEYGAMREQYMRTGEGFLLVYSITSRNSFEEISTFHQQILRVKDQDSFPVVVVANKCDLEYERQVGMNEGRDLAKHFGCKFIETSAKQRINVDEAFSTLVREIRKYNKEQQTGRPAMMGGGGSQGGGYGAKDHQEESTGCCAGCVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU24</accession>
    <name>A0A9P6JU24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_759856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU24"/>
    <dbReference type="OrthoDB" id="5582146at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="8538" checksum="DF0F2C0D0F3742DE" modified="2023-09-13" version="1" fragment="single">MDSPSSLESLIGTQAFLPTVLGHIRDAANHTALPIDQVIFQSILICLIAQDKHLIIRTPEEDVSLAVKLTVWTLSAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUA6</accession>
    <name>A0A9P6JUA6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_847652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUA6"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="113"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="186"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="24708" checksum="1DB7B9431574A000" modified="2023-09-13" version="1">MYSNYNQAPPRHSSYNAHPPAHGGYGAHRPPSAAYGGHQQHGPPAGADAQLWQWFSNVDSDKSGSITATELQNALVNGDWSRFDLDTVKMLMSIFDTDRSGTINFTEFAGLWKYISDWQKVFRHFDTDRSGSIEGRELAEALRSFGYHLSPQILRLIEIKYASQPVANGYGPPPGITFDRFVRACVTVKTLTEAFQRVDTDRDGWVTIGYEQFMSIVLSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUH4</accession>
    <name>A0A9P6JUH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_743518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUH4"/>
    <dbReference type="OrthoDB" id="2152119at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF112">
        <property type="entry name" value="PROTEIN SNA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="27980" checksum="5D8AC8E6F7471860" modified="2023-09-13" version="1" fragment="single">VDLTPKRHHGYAVILFIAGTLFPPLAVAARFGIGKDFWLNLILTICGYIPGHVHNFYIQNIRNNKTHARTPKWVQKYGLVDTAELERKKRKSQWANRYNDRLPHSALEGQALEEGQEGGSSIDLSAEGRPHRQGNGELWRPEDENYYNEGQKPTTASSGRWRYPANFEDAEPIEPPKKSKKKKDKKDRWERTQDAYSMASEGGSTKKRKKKKRRDTETASSYTNDSGEGFPEDAEGGLYGERRTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUI6</accession>
    <name>A0A9P6JUI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_783067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUI6"/>
    <dbReference type="OrthoDB" id="671439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="29153" checksum="A26A098DE71FC4B3" modified="2023-09-13" version="1">MNRSAAVQDVFMLFGDSITQGGWEPDMNSFGQRLSHVYARRLDVLNRGYSGYNTEWGRFVLQQCIDPAEVPGAPQIRVLAIWFGANDACIKPSPQHVPLPRFIENIKRMISLGRVPANSNRKETRIILISPPPVNTIVRKADLESRSPPMKLDREFDITRAYADAVRDVAKGEGVAFVDVWSRIWEAAGQNESALQKFLVDGLHLNAEGYNIMYDELIGVIAREYPEIHYDNIPYTFPAWKDINWTNPESSFKAEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUK7</accession>
    <name>A0A9P6JUK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_333777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUK7"/>
    <dbReference type="OrthoDB" id="26719at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="20"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="116"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="30233" checksum="75D02525F078B0A8" modified="2023-09-13" version="1">MENIQVWAVILDESALQDELYQRALTFVDAESQAKIKKFYHRVDSYRTLIGRLLVRRMLVKKGISLSQMTFATTQSGKSYLTAQNSNPPIAYNVTHDNNVIAMVVGPGRTNPPAFGLGIDVMKTRVPGKSSINEFIEVVGDQLSQQEHTILQAASTDDEKTRQFFWMWTLKEAYTKAIGMGLGFDFKRVEFHPQERLVKVDGQIPVGWKFRMFVLKDGEDQYQGVCADFMGNSEQAEVLPENIEGNSSWLSVEEGVPFLNTAMSVLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUZ7</accession>
    <name>A0A9P6JUZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUZ7"/>
    <dbReference type="OrthoDB" id="2977496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22431" checksum="3F48BED0F31AEC21" modified="2023-09-13" version="1">MYLDALNAESASLQIARLSPVKDDDWEMIQRGVAIVWRAVRHTFGVIFIWILDVLPSLTWTFDRISDFCAFVEANPHPFHILAWSLFFGPIILLIPCLLILELTILILFYSGFAAHGLLPGSMEGRFHVLKESFEETRESLFSTVESWTTIFNNWTSKHPALLVLRLVAAGVGLIILAGIWTSWTFTAIDPSPSVDTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVS0</accession>
    <name>A0A9P6JVS0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydroorotate oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_901452</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVS0"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF1">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (FUMARATE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="9">
        <location>
            <begin position="312"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="242"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="42289" checksum="B26CAA484CEF2E1D" modified="2023-09-13" version="1">MVLINWISISPPLLNSSCAWSSDRTQLTELYESPYTGAVTTRSATLEGFKEDYTHTVAFTNDSLTSINAYGYSPHPLSKYLEWVEEILTSHPNSTKPIIISVATAEPKVLQKMLGDIQALRHKLLDNQAPKGKARIAVELNTSCPNFPDAVPPAYDPIDKMFPLLLMAADTFVEDYTLTIGVKLPPYLMREQFAHCVHGFVPLVSTLDGERRSAISFVTSINTVGNAMLPSSLAKPIALVDKSEAPDTPKPPSKELEASSSTSTQGDNGREHNLPNGGDSSKGNQTETAHRLFMSNLFPKPSDPSQYALPGAYGGLGGEAIHAIALGNVYSFRQIIDSDMLVRSGLSGIKIIGVGGVTSKDAVGRMKAAGADAVACATFFGKNGVKAFEILGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVT5</accession>
    <name>A0A9P6JVT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_803963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVT5"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18727">
        <property type="entry name" value="PIN_Swt1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052626">
        <property type="entry name" value="SWT1_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16161">
        <property type="entry name" value="TRANSCRIPTIONAL PROTEIN SWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16161:SF0">
        <property type="entry name" value="TRANSCRIPTIONAL PROTEIN SWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN" evidence="1">
        <location>
            <begin position="49"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="403" mass="45860" checksum="4F9AA90FEFF83E1D" modified="2023-09-13" version="1">MASGGVLNFNAFSNDPGNQDVYLHSTLEQIRELANKDVEMQAPVSEYTNYLVVDTNVLLHYLEVLQQFVEDIERLGFPTVVIIPGVVIVELDRQKKRDGLGFFARRGSSWLLEKVGQRRSVKGQAYGETLKSTRNWKISEPGEKEVGSEMYNDNLILDCCLFFASSGNQSRQTFLCSADNNLCLQSESQGIHAIVPGHRWSSRDIAVGLYGNYGVDLSEFCRYKESYRNALDTAENRSSMPLEDDDTMMVDAVDEDSEWRPEHPLNLLHEAVIDHFTRLLVELVGRKGGPEVRQNPSPEEEANISRHAPRWRHFSRMSAGECLEYLNGRKGIKPRNPPAERFLLLKTRSHVPYARRGWEWARRDWEVALGNLKETAVAWDDISIPESLIYLQPHMDAAFAVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW09</accession>
    <name>A0A9P6JW09_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_743738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW09"/>
    <dbReference type="OrthoDB" id="3259294at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="11741" checksum="7E9B6CEB76CC2185" modified="2023-09-13" version="1" fragment="single">FKSKHPQYKTHGVTLLKDDIFIVPNFLGGGLPRRDIGDYEYYCLVMFTLFKPWKNGEDLKLQDVLWSDAFKAHPFSEREVQLMNNFNLIYECNDARDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWB4</accession>
    <name>A0A9P6JWB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD-repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_755324</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWB4"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000157">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="55"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="193"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="408"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="489"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="585"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="627"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="669"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="818"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="296"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="958" mass="107229" checksum="DC4EF8B0542D925B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBL1</accession>
    <name>A0A9P6BBL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tektin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158109">
        <property type="protein sequence ID" value="KAF9521353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBL1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18201" checksum="F267D64A623B30CF" modified="2023-09-13" version="1">MVPQTSSTTYRTQLGSQRKSTSVRISSVFRDVALPQKGCKGGYDYSLRELRQRRLRRIKLLQERTAERAAAEIVSVEQELHELDLITDINHRNLSISDLRLPTAQLLANAVTETLTSLRDSLELVVEEIQLHLEDARDHVSEVEISIMQAILQQDQLASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E106</accession>
    <name>A0A9P6E106_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158124">
        <property type="protein sequence ID" value="KAF9521332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E106"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="36611" checksum="209616D0A0A47674" modified="2023-09-13" version="1">MEIKDAFSTLDEERIMRWANRLTSAAPPRCFYQRLALDVASEWIYANFGTLLKNIRELSLVREGRRPSAIMSVLCLMDTTSCTSLELKGETDMALALLRGLPTMSTFSFPNVSSLSLKLPPDFRHKTLARSLEMLPGLKELELNLFEFYLDLNPCSEPMLQVSSLTKLRIRASPHVLVDSTDLFLPIPNLTHLDLCVQSFFDGSILKELIRSAIRLSKGRLTVLQIQSEVTQAQEKLVEEGFRHWAPQYAEAMDAQVKGLLALDHISCFYVCAFFSSAVTEDFKDRLYHHWKKRVSRSMIDGLDGFVRLKESWVERRKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3R0</accession>
    <name>A0A9P6E3R0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157974">
        <property type="protein sequence ID" value="KAF9521919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3R0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="469" mass="52648" checksum="BC0B7378E4655E12" modified="2023-09-13" version="1">MIAASSSFIANPCFTGFPRRVAKLTPLPPILSIVKYCIHNMYGLTKQLLSLPNELQVLVMRHYGDIDWSLHRHALNIIMFYLLDRQLLDGYLIANPVLPLDPHCLVETGNWPAAEAFFDAFAFFVVHLLAGRCFAVECALLEQFVDPEPGVTRLIEPEMLQFWTTRHSPRRFDVIFNNSHLIRRLEVGTLDHLNVGAMDGIHCLRTSLKDIPSTLPVSLTSLHLDCHANYDLPQVVSLFGLLPNLKTCSLYFLVADLAVRPGEVPVVNDHIRSIAFGGLPDSNIAPHSLFDMLIVPNLEYFAWDSLAFIPIPSLDFGAFRALFRTGTGVLCPLKLILGQPDCLMKVHAPSRTLFIPSRVQSLDSDVDLAHVKEVFCFVDEYFVDISSLSHDPHSLWSQIDIPNLTSVHFVNSSVLNPCCVDEYAKALQPILPSTCVHFWEWPSFSSKTTREGILLHNGRWSLENVLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E440</accession>
    <name>A0A9P6E440_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_919559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E440"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="88" mass="9304" checksum="1643CBAC2D3A0CA4" modified="2023-09-13" version="1" fragment="single">MVAIPVALSESTRSKVPNDSTSPTLDGDNTSDLENDILRCRPSTNLSGELNTNDLKPFEFPHNDGCNINSISASNTISNHAETSGIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5K2</accession>
    <name>A0A9P6E5K2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5K2"/>
    <dbReference type="OrthoDB" id="4773550at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040112974" description="DUF1996 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="54" mass="5829" checksum="7B38F72C4AE85398" modified="2023-09-13" version="1">MRWAPTIGFALLSAVRVHGFLRFGCSQLVTERFDPLVTPGVVSPHVHQVVGGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6R5</accession>
    <name>A0A9P6E6R5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxidoreductase, molybdopterin-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_862687</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6R5"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="5">
        <location>
            <begin position="49"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Moybdenum cofactor oxidoreductase dimerisation" evidence="6">
        <location>
            <begin position="270"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="365" mass="40645" checksum="97C01D371851A9B9" modified="2023-09-13" version="1">MASMDYSFEPPYSTYLNIQGKEPLNAEPTAAALVEFEITPEDLIYCRNHGPVREFHDNTYTLTVKGAGKGDINLSIAQLKSSYTSHQIVAALQCAGIRRKEMGAIKPVHGVPWSDGVVANCKWKGVRLSDLFADLNIMAQDKAHVCFESHATLCQDDSFYGASIPLSKALFKEDDVLLAYEMNDEPLSAHHGGPLRVIVPGYLGARWVKWLDTIIISSEESQNFYQQRDYKILPPTVEDKESAKPLWAKYPSMTVLPLNSVVAFAEFISDTMLHVKGYALPGPTGNVQAVEITVDDGTTWHPTTLLYQGGKWGWTLWEVELECMEECGKVHSRARDTSGNVQPKEGVWNLRGVAYNGWGIGTFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6S4</accession>
    <name>A0A9P6E6S4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_775298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6S4"/>
    <dbReference type="OrthoDB" id="6017046at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177:SF1">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="411" mass="46192" checksum="97D0302CA2449E5F" modified="2023-09-13" version="1">MSNNNPSGVNGYGQKNYPSDDVLSAALHQYAKEQLIVEDCLRRLSVEHGLGLIIKKSKLAQLNKKFNVPNVRNHKPPPDVATQAILEKVAQDTSQSNGVGTLKTLLANNRISLPRQVDLICSVLRDFAPEGLSRRFPGANCIRRSALVAIGPNHQHHADGHEKLNAQGLKMGGVGLNIYGIKDQWSSYLLHLVVVSNNRLETTIGQVYLDCVEKHKFIPITFVYPQGLLMTGVLYAFQNGLCEAYAADISQESPLVLQMKSIHNTPIKGLWHWFLQTFGFNIKEEIQSGYADGIYKPNNPLHKELFNWLWPQILQIQLDCFVQFWNNYRIRVQKDKPNMSGSTPYNGFVAPQYPAQDCKIMVDQPVIDALRGQIAVTRHEAMRWVDEDFAEEALTAFESIGSPDFRNVQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8C3</accession>
    <name>A0A9P6E8C3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PLAC8-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_798016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8C3"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="148" mass="15887" checksum="1AF7D8B93034DFB8" modified="2023-09-13" version="1">MSYQANPGMSVAGGNRNVKNIPIGADGRDWSNGFCGCLSEPGTCLTATCCPCITYGRLKHRHAHLNQQGTPDPEHGGCCTGDCMIHGVLTSCGFGWILQMMLRGEIRSRYNISGGACGDCLAAACCMPCQLTQESREIELEEQSFGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8F5</accession>
    <name>A0A9P6E8F5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_603110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8F5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="161" mass="18307" checksum="8278C610F46794DC" modified="2023-09-13" version="1">MDNFNLHDRRPILGIRTPGYVPGSREDSQFTRVCHVVAPATYHECMRLAYETAIEGHLPEISARLADVSNQNLASYLKLNISRSHHVFTNEPAFWLELTPTTYKTQVMACTSIGIYSPLFVVRVRPGSVNSSWNARLEKKQELVIYVLLIFSIVMFSFALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E939</accession>
    <name>A0A9P6E939_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquinol-cytochrome c chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_819975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E939"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="3">
        <location>
            <begin position="98"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="3">
        <location>
            <begin position="194"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="39194" checksum="0FDC792AD78D9CC8" modified="2023-09-13" version="1">MLPRPVVLRTLRGHAGLKSARTGARYLATSSEKPVEPPKSWLTHKVETSPTAKRVFLGLTNLFGYGSPKQVAGRRTFGIYEHIAVTAPDKDRDFWQQSCYLPPTFQSWFTVANLHIWMLTVRFRALPDAHGRHYEQALIDHFFLDIEDRIRTVLQPPNEPTTPYTLETTFYQNPLTSQNSSEGEPKKKKKGRAPDRIVTRQMKIFKEQWAGMGLAFDLALVKGDMDMAAAIWRNLLGARGAQGISYPSETAKAQNFRRSVNLVGGEVVNVAKIDVEREERTDDGSGVHDFPPEESDKYVSYPGVMLDVVQYVRRELVRLQAVTDEEILAGDWEKLKFSKMSNPVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9J6</accession>
    <name>A0A9P6E9J6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9J6"/>
    <dbReference type="OrthoDB" id="2848852at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22266" checksum="34F05026F0702442" modified="2023-09-13" version="1">MSPTPSNSTDPSNSTDDSSTISHDSRLQIAIIILSVVAVLLVGWIIFITLRVKRRQLAGEDTGPFQGTVMNDEHPAAQIIPFGGGSQSGAQGPRFNHNPGEDMRIAIRRPDGAWHFADSRTPFTPTGVSELDVLPSPMSSSASLISFSSTTKPLSRKAQEAKLDRSYRRRYDPDFDDSEPNPLVPPPPAYYPETPRDPFAAHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9S5</accession>
    <name>A0A9P6E9S5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanylate-binding protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_772200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2343366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22796">
        <property type="entry name" value="URG4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22796:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate-binding protein N-terminal" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1916"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2150" mass="241379" checksum="D11734F002C41C86" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAC9</accession>
    <name>A0A9P6EAC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_909165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAC9"/>
    <dbReference type="OrthoDB" id="124582at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="191"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1028" mass="113088" checksum="7C19B21F6596F1F0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB38</accession>
    <name>A0A9P6EB38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB38"/>
    <dbReference type="OrthoDB" id="2930838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59997" checksum="36CE137603F788A7" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBH5</accession>
    <name>A0A9P6EBH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBH5"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="164"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="296" mass="33768" checksum="C4804CCCDA2C40B1" modified="2023-09-13" version="1">MLHAEEQRQQERARSTSRGRETSAVPINFRQSTNSPSTRSRPSSTAPLQKETPPPTAQPVYNEEHENAASKIQQQYRIHHSYKALDALASQFQTLKSEFVYPRIIDFQQPSSEEGHISVHANRPPSEFDYVPEVETEETPMDVDGGEPKLAYTSVNYPLHTYTDAMDKLLMKLDGVESWGEKAVREKRRSIVRDINKESARLDRYWKQAWTDHIEAQKQEIIPATQPGTDLVDVASEDIQTQLELESDDEPVQVEAHEAKSEDDEWLQVDDHEIKDEEAAEETEVTQNLGLSADVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBT6</accession>
    <name>A0A9P6EBT6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBT6"/>
    <dbReference type="OrthoDB" id="3071584at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="58076" checksum="82A17090187516A4" modified="2023-09-13" version="1">MLDLPPELWREIASFIEKKEMTPLLGVNQLLRGCALDRIYEQTSIDLGELGQSDYLQDIGHLGYPSYAIRIRKLSISTTRNVLKTSTKAHSRRNLKASARTSLDALSKFHDILRGRKLSKSEIAQRLFLSFVRLKEIELFCVDEEEQEDFQAQMPLLLSSFQAYSSTLTSIGFSVAPLSFLSTLLPALPTVPTLERLSFRLMDYRVGSRIIEFDQILKHTIAPFISRHRETLSFLQVISNSFSKEYDLLPLFENLGYIPHLKTLEIPFVLTRLSTSQSFSKLLKRHSETLEDLILFIPFNTSRLSSTEGSFATISTPLPRLKDLAIYSIMNTLHMANHASTDLMDYISKYSSQLSKFAVYMKLFAWDDWKAFAGMNWNRLTSLSLRLSVATPTVFDAFSSNFPSLKSLSLIVSAYQESFGADGSKNKFCDEMSSRSYPTGSLTHLDIHHKNHEHHHPHLELRSSDMSCVGAVVKAFPSVISVNERHRTNFLQDLATSDSHRHRGGSRFVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECK1</accession>
    <name>A0A9P6ECK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_493568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECK1"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17366" checksum="489896B97967B8B1" modified="2023-09-13" version="1">MPKIPQELLNEIISNLWDNDNSLTCCSIAHRRLTSLGQKLLFHSIFILHEFRLQIPGALSAMTRSGISLERLSKNSPHIAGYVKALQISTPSAEDHILIDVNEQIVFEQIINPMAFCAPSLVSLKACSIVCEEECPRLTGLYARRLRGVLQHSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDD8</accession>
    <name>A0A9P6EDD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_794045</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDD8"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02668">
        <property type="entry name" value="Peptidase_C19L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01795">
        <property type="entry name" value="Ubl_USP48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033841">
        <property type="entry name" value="Pep_USP48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044743">
        <property type="entry name" value="Ubl_USP48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="164"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="12">
        <location>
            <begin position="708"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="10">
        <location>
            <begin position="999"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="480"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1075"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1082"/>
            <end position="1091"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1145" mass="129845" checksum="04081D244746E614" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEW7</accession>
    <name>A0A9P6EEW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_855682</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEW7"/>
    <dbReference type="OrthoDB" id="277961at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="75"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9527826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="127" mass="14710" checksum="CAF8CE3230BEB3BA" modified="2023-09-13" version="1">MFSSSSTTTMSEQPVVSLSSSSNGRVSGKSWKTQKTATVRSHLQPGLKTTKWDDRMEKEKKARAIKMLQAELKDEKEAEMKRRREVTKERKQAAEERRRLEEDKAKMGARKAARLRRKMGRTKKINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF00</accession>
    <name>A0A9P6EF00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF00"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="34"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="29947" checksum="5A3590BB576665F7" modified="2023-09-13" version="1">MSFYEPKSSKTQSVLSTGHPRLPISTSNPSIMVEQITLYTAKVCPWAHRAEITLEEAQLPYKRFEVNLRDKPEWYAPKVNPASKVPAVAYGGPDVQADQPSPDSQKIAESGVLIEFFADLSKDVPLLPKDPVQRAKARFFIETVTPKLFGAYYSAIRSGADPAGFVEAVEVLQQLLPPTGYAVGNWSIADAAVTPFLARAELAFTNDLGTFEAGKGKVVWARLEQEPQYERFRKYLADVKGRKSFQKTWDPEHLKDFYQKVFAKENSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG10</accession>
    <name>A0A9P6EG10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_906950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG10"/>
    <dbReference type="OrthoDB" id="2612761at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="46"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="233" mass="26093" checksum="055CE268ADC8A94F" modified="2023-09-13" version="1">MSPEKLQWRKVIKGVIAKYVSGTSGLPQGQSQMLDWGDIRENDFVILVVGRAGSGKTTFVNTVSKSELLKVDRGLSKGTRNMGTILCEKVKPRIVLVDTPPHPDEDSEMVLQDWLQSKSRKSKMKINGLIYVHQMGTTTNRFRPQETLGKLQQWGGDEIKDIPYIMVKTRWNLAVPGQDALVEEAWKEGRYKGPDPVVLQKKDDADAGWGVVKLLLENSGYNLEESDETTGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG36</accession>
    <name>A0A9P6EG36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_854823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG36"/>
    <dbReference type="OrthoDB" id="434253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="12046" checksum="E224A10E43EBDEFB" modified="2023-09-13" version="1">MSPRMKASWCHPIPRSQLSPNENLKKWLTEIHDPAEGHSKGEKNSPEYQKAQRRWEYALENFAAIIIDSLEVDYVDAKMKAIFRKKYSEDHGMIWEEEELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG59</accession>
    <name>A0A9P6EG59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 8">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_813729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 8"/>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG59"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="29938" checksum="1DA8B0B45FA89A33" modified="2023-09-13" version="1">MTLSSSNQTEGFRSLQQLFNGNKKFRQGVRVSAERAVEGDPGFMFLGCLDNRLTPSTIFNAPSGSLVTHNNIGNQYSTKDAGADAAVAYAIESLQVQHIIVLGHYGCKGVANAITKSQKVSQLVRKWIKPISDMYAVARRVEIVKLRDSRMPRRGQPNGITDSPPSDDPGFRAVVEENVKRNVRNLRENKTLQQAFSRKLKTDEGKAIDVFVHGFVYDEGTGDVNDLHVSYGPPGKVIPHIPFKAVKAAQNYQGSGGGIKKGKTWDFKAHHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGE1</accession>
    <name>A0A9P6EGE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_932193</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGE1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="22"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="361" mass="38397" checksum="E74A6E98AA02BD16" modified="2023-09-13" version="1">MSSTTTVEIPKVQRAAVIEELGKPYSLKTEHPVKQQQELAPGECLIKMEFAGVCHSDLHIRNGDWATKAPIPIVGGHEGIGRVVAIGDHSSGAVKVGDRVGVKWIGKVCGKCELCRTGNENCCLLTFQTSHGFKLNGTFQEYAVSFVDYVTPIPEEMDAAASTPILCAGLTVYKALKNAHLTVGQWVAISGAGGGLGHLAIQYARAMGYRVLAIDTGITKKELCLELGAEKWVDFKESNDLIADVKAATDGAGPHAAVIAAGDAKPFNQAIMYLRFTGTLVCVGMPGSDAFLQVPITLLIAKGLKIIGSSIGTQQDVTEALNLVSLGLVKCKHVIKKLEDVNEVLDDMSTGKIAGRVVLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGS1</accession>
    <name>A0A9P6EGS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_932043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5584001at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005261">
        <property type="term" value="F:monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055080">
        <property type="term" value="P:monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046460">
        <property type="entry name" value="UNC80_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045852">
        <property type="entry name" value="UNC80_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31781:SF1">
        <property type="entry name" value="PROTEIN UNC-80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31781">
        <property type="entry name" value="UNC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19424">
        <property type="entry name" value="UNC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20262">
        <property type="entry name" value="UNC80_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein UNC80 central region" evidence="2">
        <location>
            <begin position="915"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="Protein UNC80 C-terminal" evidence="3">
        <location>
            <begin position="1413"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1686"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2031"/>
            <end position="2056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2137"/>
            <end position="2211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2279"/>
            <end position="2299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1702"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2040"/>
            <end position="2056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2138"/>
            <end position="2156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2170"/>
            <end position="2211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2396" mass="266597" checksum="8DB0E5C103224E9D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH57</accession>
    <name>A0A9P6EH57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH57"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040122493" evidence="2">
        <location>
            <begin position="21"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="331" mass="34688" checksum="BC8BD529F062C55C" modified="2023-09-13" version="1">MVQISNAIIITTILVAPVLAVPVPPTSGHRRQQRTTEADDHEIQQHKAHRHKVQRYQGQYPKPHPHQRPAGQRRQSTFGQVASVAGGILGAASAGAGLASLIPHQDKPAQVPPVPQAQAELQARDPNSKRAKFRKVASGAGAVFGGALGVTSTVVDVASLIPDQEAPPPQPRENEGEINVREPKVGFRKVASVAGSTMGAVSTVAGLAALIPGLQDQQPQAREYDEEIEAREPKVGFRKVASAAGSTIGAVSTVAGFAALIPGLQGQQPSPPQAREYDEGVEVRGAVRHRRHRFVNGDIATIASGLAGAAGFGGAVAIQQTARDVSYNELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHA4</accession>
    <name>A0A9P6EHA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_765751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHA4"/>
    <dbReference type="OrthoDB" id="2107880at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="11938" checksum="19AB154A53E04951" modified="2023-09-13" version="1">MSARPLAQKLTSIAESWVKDPFRPNLQLSTLLNSLAAHPRLTKQAVESARALRDNDMMKKYPLSQKMLDPASRRQYYQRLVEGYEKSAQGIARPWWKGFFGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHD0</accession>
    <name>A0A9P6EHD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_289685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHD0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="343" mass="37533" checksum="B66DBCFB8D38DDC4" modified="2023-09-13" version="1">MIMPFPFTFIFNVPGLMNPFGGIGADSSAGAVSTPTTGHGHSVHSHGHAHAHQAATSVHRPNIPPIANPNGGPAPPYVPHHLGLQSLNQSQSQSQSQSQQSLAQAHLQHQLALHHPSNPSTSSSNLIIRPTRTRVSSRANLPKINRPPPEELERQQLLLHPQDPDVDSLRSLPTNRKRGWEPSFGSRAGDSSKSRAEAEAVVSSTTVSSKTASGYLGQLGRSGPGMGASWSMRGDRQEGEDEQEDEGVCGFFAFFEFYVFLSFFLSISFIHFHFHFVFLLIVRYRFCASSNHITHPSPSQITRFHTYTSRLPLPSSLYRYLPSSPIPSTNARCMRTPGVSSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI12</accession>
    <name>A0A9P6EI12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_852894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI12"/>
    <dbReference type="OrthoDB" id="2637653at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="3">
        <location>
            <begin position="37"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="373" mass="41971" checksum="424D7E3B67E1BBA7" modified="2023-09-13" version="1">MSPVLALEPPSGGTIPIYGPFKDPNFAAGAQAVNRSSVAALAFLVWDILITFDDEVEYIWPRKWTFPKFTYFGARYLPMMVQTSILLIGSELTPIFHFTSHDCFIWQVFQGVSASTIVVIVDSILILRIFALYHDNRTIRILVCVFFTLEVVGIVVGLALALPGITYDDVCLVVGVPPALIIYGASSIIFQMILFFLNVFKFVKAIRSGWGNVPLVKLLMRDGTWAFILLFFVYVSQIGLYGLKNSAYAGVLYGWLLTSFSFCGYRILMNLNSMANGERPRAIPPPNGPPHTAPTNTNIEFTTRLFSSDPNTDISDNTHLEFNELSPISEPRRLRLDHHYPHRPSNRDQYIEHQPRTHKMVATSQISTMDLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI54</accession>
    <name>A0A9P6EI54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_853024</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI54"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072670">
        <property type="term" value="P:mitochondrial tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24134">
        <property type="entry name" value="ASKHA_NBD_OSGEPL1_QRI7_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000012">
        <property type="entry name" value="tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="8">
        <location>
            <begin position="49"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="385" mass="42339" checksum="A043942CEF1C441E" modified="2023-09-13" version="1">MSVVTLARYSIFNSRRIFGYLGRRHLTILGIESSADDTCAAIVDSDGKIHSNVVIKQHDVHEVYGGINPLSAIHSHQSNMPFAVKRALKEANLDLKRDIDGIAFTRGPGMAGCLSVGMDAAKTLAAALEKPLVGVHHMQAHALTVMLTERGNEPKFPFLTLLISGGHTLLLLAKSVNEFKLLATTNDESIGRSFDKVSKLLKLKWTNLGPGDALEKFVAETDDSAESTVTPITRPLPGQLAFSYSAHHSQTKALIESHGGVEGMDIATKRAIAREFQTAAVGHLEEKLVLGLNWCRKRDIHVRDVVVSGGVASNSYLRERLRRSLDKYNSDESFRLFFPPPYLCTDNAAMIAWASTYRFSKGDTDDYSVGLLSKWDLKDLNAYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ21</accession>
    <name>A0A9P6EJ21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_875338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ21"/>
    <dbReference type="OrthoDB" id="3253976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="24999" checksum="832E86277A03B21B" modified="2023-09-13" version="1">MSHIFRSAKSGSDWTSSELNAYHIVVRNQSPKSFYVDPGFLNSDAASENTSDKTHRLLIFLDLATKANAGQESAIHDFAKELLHTSRSAQIDICLRNHALIILLVVQQEEIELKAVAAFQRNNYNRAQIGLEMKDYMSIPAITTGGTRPIFYIIPVTQELSTAVERGEYPEHLTEVKKYVVGDRRRLGEGMNNPDFRLEALKHYSLFLPLATSLWSEFLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJG3</accession>
    <name>A0A9P6EJG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJG3"/>
    <dbReference type="OrthoDB" id="2536714at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="712" mass="76764" checksum="259BEF473E467491" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK84</accession>
    <name>A0A9P6EK84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_133191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK84"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12516" checksum="0AB0EB9F68B76BCE" modified="2023-09-13" version="1">MDLRFSLEESCNTPNHLEIDSQCVNPMLFFSVFFLAYIGWPGVGFLILRDLVSLYYSRTTSWSMNLICWKGVRELVELNGATRNYREPSRGCRAYRAYRATAHHGISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKI1</accession>
    <name>A0A9P6EKI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_868731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKI1"/>
    <dbReference type="OrthoDB" id="10258882at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated" evidence="2">
        <location>
            <begin position="208"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="713" mass="79795" checksum="1E9CD1EAA302396C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKS0</accession>
    <name>A0A9P6EKS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fusaric acid resistance protein-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_761159</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKS0"/>
    <dbReference type="OrthoDB" id="68611at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023244">
        <property type="entry name" value="Brefeldin_A-sensitivity_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF1">
        <property type="entry name" value="DUF2421 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02047">
        <property type="entry name" value="BREFELDNASP4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="704"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="727"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="8">
        <location>
            <begin position="676"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="7">
        <location>
            <begin position="865"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1066" mass="120575" checksum="3D73DFA2FFF98827" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKT6</accession>
    <name>A0A9P6EKT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_892384</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKT6"/>
    <dbReference type="OrthoDB" id="5141738at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000044">
        <property type="entry name" value="Hexose transporter Hxt3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF75">
        <property type="entry name" value="GALACTOSE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="18"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="508"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9530744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="549" mass="59996" checksum="2FD5AAEC64089339" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELF2</accession>
    <name>A0A9P6ELF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_904999</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELF2"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="243" mass="25733" checksum="54B2C7638D7564D0" modified="2023-09-13" version="1">MSKIILITGANTGIGFELVRILAEKGHTVYLGSRNPALGEKALQTLVSEGFQTVKFVELDVTKPTTISAAAKFIEAAEGRLDVLVNNAAISGLQLEQNALKVDVSTIRQTMETNLYGLINTTQIFLSLLRKSTSGAPVIVNVTSGLGSGVYQSRPGSEAHFTAYNTSKAAVNSYTIALAHELKSEGFKVNAVTPGLTATQLNGFAEKGNSARDGALELLPCVLLDKEAGTGLFFGPDGKEFPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELS4</accession>
    <name>A0A9P6ELS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_881645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELS4"/>
    <dbReference type="OrthoDB" id="3066463at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="3">
        <location>
            <begin position="82"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="41541" checksum="C4DEDE61AC6017CA" modified="2023-09-13" version="1">MSGLSGPLDRLNQGKVSAAKKLIELQLVTTKIMSLRSDLLVDAQPSHTFTQFLVQGLEETTPMDVDNRLARQVWIERLTVSSAVAALAFSVFDFILTLGDEVNMIWPQNRRSPTKWIFFANRYAGIIAQVVLTFKTVIFTEPECSRSTTRMLYTLNILTFGIVMACTQAVLTLRAYAIHRKDSRIAVVMSAILLAELAAFPGAWHLTAGEGKASILCMKSFTTRECFGFGAIFLLPQLSAIGLSSYRLLSHDWKAFPIANQVLQDDACLLSVNVSAFILTSALSLIDKDFNYVMHWWLLAVYPATGTRMILNIHQNGLRENHCHHSSADLSSCMFSDLLLVSNANSEFDRCDSPKFTKSSGPTSPSGLEEKFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELU0</accession>
    <name>A0A9P6ELU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_104573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELU0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12818" checksum="987E37530B6F6BF9" modified="2023-09-13" version="1">MLLVLSAFLHPWCTNHVDVLPFPYSFMIFNVLYNTLCLFFSSFYSLPLLHITLNRRIPNLSRVTSTPPTYPSLLDIQRSYYISNSNQFNHSTFYKHDLFSPSHMVYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENF9</accession>
    <name>A0A9P6ENF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_832803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3183767at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1289" mass="146879" checksum="64F8A69BA339CAAB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENR2</accession>
    <name>A0A9P6ENR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vacuolar import and degradation protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_807585</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5364245at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="11">
        <location>
            <begin position="507"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="893"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="674"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="785"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="958"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1043"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1103"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="794"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="963"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1103"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1165"/>
            <end position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1283" mass="142662" checksum="3D422DD54395808A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP31</accession>
    <name>A0A9P6EP31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP31"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="360" mass="38768" checksum="570FFA9F18F87D12" modified="2023-09-13" version="1">MATLGAAYASGYRVPTPPILQHFSHALWCSIGVAGLGELEDIIDAEFTASQDEHILAHAGHPNDWWNDLPQTPTELAEAGYNISTVLGGLMTINNVVKSAVHPPSASGAPQIEDAFNIPRNIYPWQKSDSASGPSAPQASTARPLDPAHKSILLSHLEKVIKSIDSTFVFSQAALARAIEASEQSQERSTCLQKLLELYEKDELHLSNFEESKGTFRTPAVGTEHSDASDNTDGSTPSSESSSNPTAVQTRLSRKAVNTFQISSSYSSSYNAAISPPDNRHLDCPNGVFYPPSPTVTDSDPRVSPATTEITTSSSDTEDESSTRSEDSNPDEPFDVSDSEDDTNGSEWEQPIDSDDEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP73</accession>
    <name>A0A9P6EP73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DEAD H helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_903913</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP73"/>
    <dbReference type="OrthoDB" id="18781at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055227">
        <property type="entry name" value="HRQ1_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="MZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22982">
        <property type="entry name" value="WHD_HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="299"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="523"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1033" mass="115314" checksum="D71C26F4B422322B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP74</accession>
    <name>A0A9P6EP74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP74"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="1">
        <location>
            <begin position="237"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="553" mass="59791" checksum="2B252A99BF94ECD1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP81</accession>
    <name>A0A9P6EP81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_782959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP81"/>
    <dbReference type="OrthoDB" id="2662502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="383" mass="43317" checksum="8A74C3B6B8DCBB74" modified="2023-09-13" version="1">MPSSPNSPSSDDNTSEVGRLKRQVVALQDELEEARGSRTKRSETPVTRGRGIRRLITLFESLDGLIAEADTRILAEKDGVVRFRDQSELKRNADRTFESYELLLSLVPPFKTLIQTDADEDTFRQYTASLQKGANDARSDDVRRIKEEIAVWLNHNNPTATPLSPKSRDNRGLQNDVTGRLLCPIEHKWDDEKNRADMQNAVIDISQDFFITCLYKKGTADPSDVENGFLRSVLLLKTFCAVFTSPTSSEDLEEPEDDVPARKKRKTSSQKKATKTNVAGLLRMEGKVTPRAIAYAAVLLVFNLTDATQWTETYNGFNFRAFYNFIVDFFEDTPGAAAQRRANMLLTWWNSQVFQDQHAPTSSGLKASQDKLLAQRLQREQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPE2</accession>
    <name>A0A9P6EPE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPE2"/>
    <dbReference type="OrthoDB" id="2538461at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="35809" checksum="3771909B2F19D729" modified="2023-09-13" version="1">MFKRVEKRRRKRQEEDDLSLDDELKEIMGFQDTDSEESDSDSEVESGSGASGDELDDKAGNNSELEERSDEGVDEQEEEEAEDPEVSVSNALTDPVYIVSVDPDVRACIVCPGKLLKGVNMVQTHRTSKAHERRYKQFKTIAATAGKNESAWIVLKRHAEDNPKLSLAPSTTRISKRGEKKKRYLERQKAKRENIKQLKAKQVAESSKLDQPSDSGKRNPSSNRKKESQKTNTTVSIVTPSKKRRKFVKSSNPGDTSLNQLTGDLVSKTIHRQPAASVVDTPTAQAVEGNGKKAVADIVRSTTERTLAARSKSSGRQKPSKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPH9</accession>
    <name>A0A9P6EPH9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_626976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPH9"/>
    <dbReference type="OrthoDB" id="2317741at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040330276" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="37"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="134" mass="13891" checksum="AA5CB77841640826" modified="2023-09-13" version="1">MKLSIFATLATVFVAGVNASAVIQRAAQDVYSPHITSPTAGVVWTSGQTQTVTWDTSDAPAHITNRIGRIVLRKGATTTPLVLADNFDILDGKAQVTVPNVVAGSDYEVVLFGDSGNISPEFTITGSGLAAATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPI4</accession>
    <name>A0A9P6EPI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Snodprot1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_902961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPI4"/>
    <dbReference type="OrthoDB" id="4898945at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22778">
        <property type="entry name" value="DPBB_CEPL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040210229" evidence="4">
        <location>
            <begin position="17"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="141" mass="14634" checksum="910C16439A4AD015" modified="2023-09-13" version="1">MKFAAVTLSLLPVIFALTTSYDTAYDNKGQSLATVACSDGSNGLLTKNYTTFGSLPSFPFIGGAPPIAGWNSASCGTCWNLTYTAQNVSKTITVLGIDVATPDSFNIAKAALDALTGNQAQQLGRVPVTAVQVNTTFCGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ04</accession>
    <name>A0A9P6EQ04_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fanconi-associated nuclease</fullName>
            <ecNumber evidence="8">3.1.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_846486</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.</text>
            <dbReference type="EC" id="3.1.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the FAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.1" evidence="8"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ04"/>
    <dbReference type="OrthoDB" id="76364at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070336">
        <property type="term" value="F:flap-structured DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004528">
        <property type="term" value="F:phosphodiesterase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22326">
        <property type="entry name" value="FAN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033315">
        <property type="entry name" value="Fan1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049132">
        <property type="entry name" value="FAN1-like_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049126">
        <property type="entry name" value="FAN1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749:SF4">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21170">
        <property type="entry name" value="FAN1_TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00990">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="10">
        <location>
            <begin position="779"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="901"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="906"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="970" mass="110365" checksum="9E15EC374566FD5D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ48</accession>
    <name>A0A9P6EQ48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA polymerase delta catalytic subunit</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_890207</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ48"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.730">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="11">
        <location>
            <begin position="178"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9533077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="510" mass="57793" checksum="162CAB9223BBB841" modified="2023-09-13" version="1">MTSTPPLAISSSNAPITQKSTDASKKRIVSEGSFARVLEEMGKLEIEEPETRTCTRSPPPEIEETLSSLTFQKVDIREGYDPRGRSEIRLFGVTKAGNSILARVRNFEHYFYYPAPTAFSEDDLVPLLDLLNEPYPSSAPPIASIELERQATSPNGPLVFKTGKCGYRDLFKAPELSYEAGIPYFLRYMLDTGITALSWLKIPAQKYQVISKNDCISTCQIEVSLESEADLLICDVVDNKEKYAPLRILSFDIECNIATKAGQFSSPKTESVIQIGNMVTTYGQSTPFVRAIFTLDTCSPISGTQVKSFEEEKDMLLAWQKFFMEVDPDIVIGYNITQFDIPFLLERAWVLKLVKFSYMTRLKKCSQRLNFSQGRPKFNTCPGYDGRLVLDVFHHIREHHTGLQGEGAYKLNSVSSHFLNEKKEDIGYDQIPKLQNGDANSRRDLAIYCMKDAYLPLRLLEKLKCFEIEVKEAKEARVPFNVLRLWRSLQNTAKRHLDGLDRCYVVADPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER01</accession>
    <name>A0A9P6ER01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MGMT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER01"/>
    <dbReference type="OrthoDB" id="2548197at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052520">
        <property type="entry name" value="ATL_DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42942">
        <property type="entry name" value="6-O-METHYLGUANINE DNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42942:SF1">
        <property type="entry name" value="ALKYLTRANSFERASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="2">
        <location>
            <begin position="7"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="14263" checksum="53D705B80EEB6AA7" modified="2023-09-13" version="1">MSLDVAEFHAEVYTIVRLIPPCRVTSYGHIAKLAGMPNHSRHVGQALKFLPANTTPLIPWYRVIGASGTISSRGPGTDGARRQRNALVAEGVDVTDGRTGDFRIDLRTYGWFPTRDEVRAMQQIEAEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER91</accession>
    <name>A0A9P6ER91_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase I subunit RPA34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_757527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER91"/>
    <dbReference type="OrthoDB" id="76224at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013240">
        <property type="entry name" value="DNA-dir_RNA_pol1_su_RPA34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08208">
        <property type="entry name" value="RNA_polI_A34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33176" checksum="2074B0961D7E9BC3" modified="2023-09-13" version="1">MSATPPPAVSEKKKYTVNKPKPKGKKKATAVASTEGRNEGEESNWDYKPPLGAVLVEDQEGDAGNFDWDVVNDDDDLELCLIRVPDAIKPKHMENLKIDFPSRTTHSTCVGTLQRKVASFDIWSIGSSDDKNIELPVGEEIKSISCLLPRKKKKGKLYPGEFSVDSPKPITNFFVLAAQPVLPIPPETDVGDSDVGAVEYKNPPRYSYPKNVLKHRFLPTGARGKKEGESSEAELINEESDIQMDEDSPLVELPSSDKKVKQDEEAIGEVEPDLELKKGKKRKGDVVHAPVKRSKRTKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA9</accession>
    <name>A0A9P6ERA9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="5">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_757359</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="5"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA9"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="6">
        <location>
            <begin position="79"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="7">
        <location>
            <begin position="203"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="32915" checksum="02C329892B656F5B" modified="2023-09-13" version="1">MGYSLCVIGCGTMGIAVLSGVIDSLQSSSRLNGLSLSKWESHTPGTQTPTCIHDTTLPSRFLATCSRIETAERLKGLFSGLGELGQSVEVLAGKNVEAVMSADVVMLCCKPQLAHRILNEPGMKEALDGKLLISILAGVRMSQITEWVGPTTRVVRAMPNTPCKIREGMTVVSTLSPSDSEEADRAIILNIFSSIGRCRFLEEKHFDACTALSGSGPAFACIFLEAMADGGVMMGLPRAEALELAAQTLQGAARMVLGGGIHPAQLKDSVTTPGGCTIAGLLALEDGRVRSTIARGIQIATEKASELGQPTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERV9</accession>
    <name>A0A9P6ERV9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HBS1-like protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_223685</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERV9"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015033">
        <property type="entry name" value="HBS1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037189">
        <property type="entry name" value="HBS1-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08938">
        <property type="entry name" value="HBS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109732">
        <property type="entry name" value="HBS1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HBS1-like protein N-terminal" evidence="7">
        <location>
            <begin position="14"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="166"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="632"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="649"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="661"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="675"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="692"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="742" mass="80826" checksum="DB7F7CC3FE0C4242" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESB2</accession>
    <name>A0A9P6ESB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_781373</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESB2"/>
    <dbReference type="OrthoDB" id="29879at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000006">
        <property type="entry name" value="CorA family metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000008">
        <property type="entry name" value="CorA family metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF51">
        <property type="entry name" value="MANGANESE RESISTANCE PROTEIN MNR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="773"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="801" mass="88833" checksum="2D6B2C043ADC96DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESM2</accession>
    <name>A0A9P6ESM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">NADPH--cytochrome P450 reductase</fullName>
            <shortName evidence="14">CPR</shortName>
            <shortName evidence="14">P450R</shortName>
            <ecNumber evidence="14">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_756475</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="14">Binds 1 FAD per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="14">Binds 1 FMN per monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Single-pass membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Mitochondrion outer membrane</location>
            <topology evidence="14">Single-pass membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Single-pass membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NADPH--cytochrome P450 reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the N-terminal section; belongs to the flavodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="14"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESM2"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06204">
        <property type="entry name" value="CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000024">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000018">
        <property type="entry name" value="NADPH--cytochrome P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03212">
        <property type="entry name" value="NCPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023208">
        <property type="entry name" value="P450R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000208">
        <property type="entry name" value="P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14" id="KW-0274">FAD</keyword>
    <keyword evidence="1 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 14" id="KW-0288">FMN</keyword>
    <keyword evidence="14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6 14" id="KW-0521">NADP</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10 14" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="15">
        <location>
            <begin position="64"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="267"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="70"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="121"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="454"/>
            <end position="457"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="472"/>
            <end position="474"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="493"/>
            <end position="496"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="641"/>
            <end position="642"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="651"/>
            <end position="655"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="727"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9534516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="728" mass="80595" checksum="A3ACF2449C32F67D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESP2</accession>
    <name>A0A9P6ESP2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein-tyrosine phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_844411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESP2"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14522">
        <property type="entry name" value="DSP_STYX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000036">
        <property type="entry name" value="Serine/threonine/tyrosine-interacting protein a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="99"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="238" mass="27534" checksum="C7066760A58CCE77" modified="2023-09-13" version="1">MNSTMPAQLSEEQLKQVIQGPIDVEWRYEMRRECQEILPNLLLGPFVASKSLETLQALHVTHIVCIRDAKEAFSVKPRFPDQFQYLVLDVEDNEEQNLIRLFPEAKRFIDKAIENGGRVLVHCNGGISLSPAFVVMFVMQHYQISWEDALHLVQNRRYCISPNGGFLTQIKEYEAIYKANVAHASFPQALRPVARRKREMDDDDHEDVAEEDRDRKRPLVAAQSQERMDMDMDAMETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESQ6</accession>
    <name>A0A9P6ESQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="4 12">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">5-proFAR isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_873161</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="4 12"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESQ6"/>
    <dbReference type="OrthoDB" id="446074at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000110">
        <property type="entry name" value="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 12 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="29580" checksum="64C32C12EEAF7834" modified="2023-09-13" version="1">MSGKNHFSLFRPCIDLHGGKVKQIVGGTLSDDLKTLKTNFVSSKSAKEFAELYKANNLHGGHIIKLGPGNDEAATEALATWPDNLQIGGGINSSNAKQWIDLGASKVIVTSYLFPHGKFSLENLKVISTGVGKERLVVDVSCRKRGDIWLVAMNKWQDITDMEVSKESLDLLSEYCSEFLIHAADVEGLCKGVDEELVKKLGEWVTVPTTYAGGAKDISDLLLVDQLSGGRVDLTYGSSLDIFGGSQVKFEELVKLNTQQKEKTSFGNRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESY1</accession>
    <name>A0A9P6ESY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_20673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESY1"/>
    <dbReference type="OrthoDB" id="3139566at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="60464" checksum="DBA1941D93804EC6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESY9</accession>
    <name>A0A9P6ESY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_888289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESY9"/>
    <dbReference type="OrthoDB" id="2679643at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="32"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="46948" checksum="7C2BCB947015F29D" modified="2023-09-13" version="1">MPDGTTVLVITVSQLLQPEFRLSLVGLEVSKCLSIALFALLLYEYFLTVDEEKEHFWSGPYSISHYLFAFNRYFTPIIVLLNLVSAYISNCPIGSTLTELTIGFFVVNPSVQLYVRILIKKIEIDTVISCQGMIPLVFLLVIFSMSIIKAILVARVWYQFPGSMLIRLFMVFAFLLTTSVSLAFLYISLNKLEILSIQGAGMDIVGCRATRPKLFWRIYLPDLLMHTLLYALTVYDVITNPEYRENTNVRNKLLKEGGAFYFIVLLSVTLTSLGSFLTNFPVVNVPATFSPTMLVATSIATSRLMFSLRRTTREVESSVNESTFQFVPMPLTNINIISDFPPLKKVPSSRFSADSDIISKPTSVRSQNKFVLDLGSVDEEKGMANHFSSDNRSGILGGWEMVSVGDMVMRAKRWMHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET68</accession>
    <name>A0A9P6ET68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_30269</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ING family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET68"/>
    <dbReference type="OrthoDB" id="2505961at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16859">
        <property type="entry name" value="ING_ING4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF42">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="416"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="158"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="8">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9535736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="51256" checksum="395D5860581E595A" modified="2023-09-13" version="1">MAQTVVGQLNPPYALTLLSEYTHTLDSLPIDLSRNFADLRELDAVLSSSIQSITSKIYSLITMIEEDKAPKEDRLWLLSDIADEAQRLKLGGEDKIRVACQGADNLKGHASHLRALTDNIPGFDSSLLDRKTTYPHVSEHAYRPTFVMETGRRRRGGLGSIMVASNPDPSPAKRKRVGGKEDDIDITGRSPKKPAHNEGSSRARKKKTERGASPSESLLSVATPLPHPLTHSTSGSGRSGGGGSSTSRGGGGQGANVSGSTSAANKRRTGANATTRGTPLANEVYSASHDPHGQGHTNGSSSRRGGASSVNGGDAYGNGLPPSSSHPSLPVPSYQNGTNGHHHANGYDVQANGLSHIAGSQDWNSIPRAQQLEGPGMPVARSASIHSTAASVAVVNGVANVDSTDAGDADGDGDDRTYCFCDKVSYGEMIACDDENCEREWFHLGCIGLASPPQGSWFCDACKTKKTGKKQARGGGKRRTGGGRASGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUL1</accession>
    <name>A0A9P6EUL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Asparagine synthase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_780025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUL1"/>
    <dbReference type="OrthoDB" id="10252281at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparagine synthetase" evidence="5">
        <location>
            <begin position="294"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Asparagine synthetase" evidence="5">
        <location>
            <begin position="481"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="590" mass="66016" checksum="AF5EA6F9D840C622" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUN3</accession>
    <name>A0A9P6EUN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L7/L12 C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_843313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUN3"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="116"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="19385" checksum="1F24CF9B1870176D" modified="2023-09-13" version="1" fragment="single">MASRCSSALRALSRPTTSIRYSRSWNSARCLATATEAQSSSSAPPPLAASKDASINRIVDDISGLTLLQAADLVAQLKSRLNIQEIAMPTAAAAPAAAAPVADEPAAEKPKEKTVFNFKLESFDAASKPKIIREVKALVPNLNLMDAKKLVESAPALLKENVSKEDAEKLKKAFEALGAKITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVC1</accession>
    <name>A0A9P6EVC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_841987</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVC1"/>
    <dbReference type="OrthoDB" id="2146436at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF1">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040296266" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="9">
        <location>
            <begin position="16"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="22372" checksum="C03E1F12C6E8E393" modified="2023-09-13" version="1">MLKMLTLIFCLIASASAHFHLLYPGPRGAFVAQNELQFCGNLPEVTTNRTTFPLSGGYINIQTGHPNWLLGVIISTDADPNTWEDFNIAGTNNQQFVKYYGKQANPGTYCIPLDLKASGIAGVQEGSNVTIQAIFQGGDGNLYQCADLTLSANASPPSDQPCKNVTDTAAVSSLAAASSSSAAAAKPSQTGGASHLAPAVIVVTLLGTLIVTLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIK5</accession>
    <name>A0A9P6JIK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIK5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040217496" evidence="1">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12374" checksum="7E078C9FD72BAE7B" modified="2023-09-13" version="1">MELTLSIIMILLLLAKDVLSEENHSDLRITLEQKHPRRRFVTPTTTNDLPNISPWRKLVPLTRFLIEIVTPSPPLEKKNTIKLWKSGVIALLTSGLLAPTKLWRSLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ68</accession>
    <name>A0A9P6JJ68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_863997</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ68"/>
    <dbReference type="OrthoDB" id="2015537at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="10">
        <location>
            <begin position="85"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9522710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="446" mass="48476" checksum="6A95E5F4C32EAC02" modified="2023-09-13" version="1">MPIHGLKPRLQPVHPAHFDIEKVIRPNILALHPYRCARDDYKEGLLLDANENSFGHSITRGAESTNGNANPVDVDMPIELVSTLQLDLHRYPDPGHPDVKRRIASLRGLLSLLSSQEEEAEVLDHIVLGVGSDEIIDLLIRTCVQPGGAEKILITPPTYGMYQVGAQINDVGVVKVPLVLNGDKGEGGVDGRFSVPLDKIKEAVDVDPKIKMIFLCSPGNPTGTLVSLGTVVSLLEYEPFKGIIVVDEAYIDFVDDPQGQSAVSLIKKYANLCVMQTFSKSFGLAAIRLGVAFAQPPLIQVLSNTKAPYNVSSSTAHLALSALSPPSLAAMQKKLATIQLERKKLIEALNNHPNLKQLSVGAVIGGNDANFVLVPILQNDQSETEERQPDSNRAQVIYRTLAETRGVVVRYRGNEPGCQGCLRITVGTEDENQVVLDKLEEVLKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJC4</accession>
    <name>A0A9P6JJC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJC4"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="21115" checksum="991D54EABB5ABE2F" modified="2023-09-13" version="1">MTMFRISKMQKGGTLSSIVVRNFKPARAHKAQWVEESSLEFQNIYDQPNAACQTAGDNWKLEGGIVGIVAKMCIDSLLRDKLFEKGILALIIRMLDINETRHVALLALSTITQHGGIHALGKIAVRAPHFIILMRDHPDDEKIAELGHCTRVVTEGGEKPERPDLPHNFDMVEVLKSLSRQSNDPTAILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJS1</accession>
    <name>A0A9P6JJS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_952036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJS1"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="65"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="517" mass="58171" checksum="EA969F50574985A1" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK48</accession>
    <name>A0A9P6JK48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_652004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK48"/>
    <dbReference type="OrthoDB" id="20729at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="16868" checksum="17C714047F6E7093" modified="2023-09-13" version="1">MSPEELRVKAVEAVKRGNLEQYTRYEANQFAAAEKEYKKVRSNIPGAVHRAWERSELVLNSSTTPSTVGSGILSPSVLCGTKKQRWNAGPKVVVSPAWPWNRAGPEEVELETIKSTPVRVTAAVEGEVKQVSLSGPSSASVIRSKGKQPLRESSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK52</accession>
    <name>A0A9P6JK52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK52"/>
    <dbReference type="OrthoDB" id="2945238at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="34943" checksum="1852181E49C5BE21" modified="2023-09-13" version="1">MPSTRYSSSPRKYPHSSDTELFETPPRKRFCPAEDEDDLSYSSASPQKKQRRQSPKKPFSSDLNLEQALRLSARSTVDHVTLLSLKDVPHDERSIRASIKSIIVSSKRSVMKHFTKAKHLPLETELYAKWLEGVEYVAVGLEKALGAKVPGTRRRVPGFGRSIYAITFYLVDEFIDEVSTHHDGWTSPDEPSYYPPTLSLVEEAKDDSTNGRSDIAVKGAEAILRRFDAIMAAAAKRYKVERGRNNPSLAERISAQEHALAKGCCLLCEQTGYGSDHHDIGDVLMKHTRDVLTQWKNEYDDCEDQLVDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKR2</accession>
    <name>A0A9P6JKR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_641482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKR2"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF5">
        <property type="entry name" value="STI1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="16034" checksum="EE23E993C133A819" modified="2023-09-13" version="1">MAANIRKLGAGSSRGEILKNEGNSLHQQGKYRAAYAKYSEAIKEDPQSPVYYANRAASSLALKECVLKSTQFPSLADLIHRDKVPGRSFGCEKGLIVLSYLFERFNLPISPKATKLEPKYGKAWGRLGTATIVRRCSVMPRKNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL62</accession>
    <name>A0A9P6JL62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_773834</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL62"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="353" mass="38993" checksum="8C1339A8776A6CA1" modified="2023-09-13" version="1">MKAAPSSPDEPIKGKKSSPTLGPPEEVSLQSDSEPPLKKSKCLGDSNSLLDVSRLLLSRPDAVFATPQTGKYDASGLVPHYFNEEEVPDHLKKYFYQRVRYFSLYSTPPGCLLDEEGWYSVTPELVADQIAERCRCDTILDAFCGVGGNAIAFAKTCQRVIALDISTTRLALARHNAQIYGVADRIEFILCDYRTFVKSQLCLPSSNSSDSRTTERRKIDVVFLSPPWGGPSYLGGDEQGSSEAPIVRQSTEANHPSFSLANIKPEHGSGLFDLARQITKNVAYYLPRNTRLEEIGVLLTEEERRIGRHKDGSPAGTPDSTEQIEVEEEWMGNKLKAITCYFGGLVEGQGDMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLA2</accession>
    <name>A0A9P6JLA2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_897251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLA2"/>
    <dbReference type="OrthoDB" id="514248at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="433"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="433"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="56057" checksum="BC67C4637456F680" modified="2023-09-13" version="1">MHPRNPYRAPPDFDSLAQSYPELKRCLVISTKNAGGQFVTINFRDEVALRKLTEAIMFRDFGVKLKIPDDRLCPPIPNRMNYVLWIQDVVQHTLGINAQKQGEIIRGVDIGTGATAIYPVLLSSLEKTWEMVGTEIDDASYLCASSNIETNHLQSRIKIVKAEKLNPILQPLNGVIEDSMYHFTMCNPPFYSSSKEIESLAKGKHLPPNAVCTGSTTEMIYPGGEVAFVGKMVDESTTYRRQCRWYTSMLGKLSSVEKIVQRLRSHNIANYAITEFIQGRTRRWAVAWSFFEDRLPDSISRMNVSSSHPLSTYMPPRNTLSQPLQSSTAVDLRNIETALENALKLVQRITLTVTSDDQPPNAQVYILEAAQNTWSRSARRQQRHGGSLDFSNPPSSAITMVCSVKVSQGSPISEVPLQNKSYQADEWSEVLDGLDEDDDMDIDDSSTVEEKKRPDTQHTQKPLSLVFQWLSGEDRAMFESFASHVGRKVGVVVSSTNSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLA7</accession>
    <name>A0A9P6JLA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLA7"/>
    <dbReference type="OrthoDB" id="2677451at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="26321" checksum="876F3997914276A3" modified="2023-09-13" version="1">MKQSTRRTKAVFLTVNPQAPETTKKKTNGNASTDMGAHQQLRKLEHDLRCAEHPGPNRWCFVSHQELSLWAQKVCDDRAKHVCVVSAPKKNTPDIHVHINNAPSADDSRHITQSQKRSCTPKSASESDLDIEPLPLSEVINNLHLHYPLLDLPQYPPALKKKGIVYANSVSTFPRDFYVGSGMAEGAVGPFLAGVRKARKNKKEKHLCKCSHISDKENVMVAGPSCCPLNPDESFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM18</accession>
    <name>A0A9P6JM18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM18"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="709" mass="76200" checksum="A535FDC655BE7898" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM66</accession>
    <name>A0A9P6JM66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRTase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_509531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM66"/>
    <dbReference type="OrthoDB" id="9973266at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25138" checksum="90FACDC27DF6FCD8" modified="2023-09-13" version="1">MSEQVQHWHVTYNDIHDLIRKATPEIAAKFNPDILIAIGGGGFFPARVMRTFFRETTNNKTLQIQAIGLSLYEPVEGTTAEQIGNEVIRTQWLGPDPGKILLGKKNLIVDEVDDTRKTLQSVPLSLSLARHLRPDSYALTELKKDVEVELLNYPEPERNALRTKTQFAVFVVHNKLKPKLAELPQEVPYFAGEEVGDVWLDYPWEAVDIQRHDALAAADRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM93</accession>
    <name>A0A9P6JM93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM93"/>
    <dbReference type="OrthoDB" id="3061561at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="142" mass="15857" checksum="4C2F8C91031E8605" modified="2023-09-13" version="1">MYSFSRFPRVSSRQLFHSGDLSTLIISIDDFFNDGTTISFHQPHSALDEICSVTTLISLVGSAFCGLHLIAWSFHFPTHGARLIWQISALITTFVPPVRGLIVYLLFHIETSLNVVASVYIVARFVLVAEAIWILQYLSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMY3</accession>
    <name>A0A9P6JMY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMY3"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="43760" checksum="4CBC06635E905639" modified="2023-09-13" version="1">MASVEVGHHDGLPNELFDIILQQLNGDYPTLSQVALTCKLLLSEAQALLYQSLCYTVKVGSLFYSPPDVGPPPRAYILNPSLAKHLKRIVYTESPEGKQHEDMHTILSAAFSNLYPQLKSLEVTFWEGLPPGFLKHGRFKLEVLHMSGSNAPENILRILKRQPELKCLRIASRRRIGIDKIPLPSVANLEVLEGTSSVVLSVLPSRNVKTLVWEPSPLERVQLENFESISAELNALTALSYALSEDLPPFDNIANHLRNLKHLTVEHKWNARATGYARARQSSLIKVMPEYLASLSALRGLTLSISDFHYPQDLDSNHIDKFFLQCPSLRFVDIEQQSGLDSNRVKRQFERWVKRQDGQATKLDKVLQYNKFPRTYYIDSSLFESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN56</accession>
    <name>A0A9P6JN56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_770207</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN56"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="428"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="907" mass="99817" checksum="95032E7862DB71D7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNM6</accession>
    <name>A0A9P6JNM6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_837120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNM6"/>
    <dbReference type="OrthoDB" id="3271094at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="172"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="338" mass="38117" checksum="7C69741ED62D6FF4" modified="2023-09-13" version="1">MPPLAPSRLRPSSGEPHIRKSRSAFTDTRTKLNVTRSLRSKWLDKIKQKRKVREAQNWGGDTTAKGHITPAVQSKIKFRSKSTSAKVGSHVQREESCEATSFCSWSSSPYCNFEGEFPDPMEDIVGWGLNSPGADEESFGRFMGQALPRGIVTIADQSTQILGSGPNGCDRQKFTIPIEFAMSYETFDRAVKLLFRGDTMEARLQQNYVEKGLYDFGIDEGRRVKILNETDNWSLIGPGTNITMRVIQAQQSMLDRHGQYQCPRPGILIPRSKGCAGRFQISGGGEDLSNVWDNYPFELVLLRNIHLKTYEAQDLDPKYFNQFFDFFSGAETIRLGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNN2</accession>
    <name>A0A9P6JNN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF8040 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_738929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNN2"/>
    <dbReference type="OrthoDB" id="1681765at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058353">
        <property type="entry name" value="DUF8040"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26138">
        <property type="entry name" value="DUF8040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8040" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="94" mass="10630" checksum="50C891C1FD673D9B" modified="2023-09-13" version="1" fragment="single">MCVTGLSVQHVGEQFQRSNETISHYFRLVLDALSSGPFYAEYVKLPLTSDPASPVLQDNSKFWPFFQHVLGAIDSTHINCCPSALERQMARDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP04</accession>
    <name>A0A9P6JP04_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit SPC19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Outer kinetochore protein SPC19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_836123</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP04"/>
    <dbReference type="OrthoDB" id="3361333at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013251">
        <property type="entry name" value="DASH_Spc19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08287">
        <property type="entry name" value="DASH_Spc19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="105"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9527972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="20727" checksum="45AA4054BDFEBB0F" modified="2023-09-13" version="1">MSRQPLSRANVKARESVFASGPEHYIGDAQARCPPDLEECVLALEDCCEELYEAQMLLRNGTRDLPRMTRLLESDRVFLLVNERTIKDYKLNLAEEVEPAISELIQRAEQGLTSLEKQQQLLETKVENSKLRTRPAVGTNAVQKLENRRLQTLVKQREKLEAEVQALEREVLEIDIKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPA4</accession>
    <name>A0A9P6JPA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ADP-ribosylhydrolase ARH3</fullName>
            <ecNumber evidence="2">3.2.1.143</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ADP-ribose glycohydrolase ARH3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ADP-ribosylhydrolase 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">O-acetyl-ADP-ribose deacetylase ARH3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Poly(ADP-ribose) glycohydrolase ARH3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">[Protein ADP-ribosylarginine] hydrolase-like protein 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">[Protein ADP-ribosylserine] hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_856105</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>alpha-NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+)</text>
            <dbReference type="Rhea" id="RHEA:68792"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:57967"/>
            <dbReference type="ChEBI" id="CHEBI:77017"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ADP-ribosylglycohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.143" evidence="2"/>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPA4"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004649">
        <property type="term" value="F:poly(ADP-ribose) glycohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="entry name" value="ADP-ribosylation/Crystallin J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050792">
        <property type="entry name" value="ADP-ribosylglycohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16222">
        <property type="entry name" value="ADP-RIBOSYLGLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16222:SF24">
        <property type="entry name" value="ADP-RIBOSYLHYDROLASE ARH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="ADP-ribosylglycohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605502-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9527405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="420" mass="47133" checksum="EC99097B29470D82" modified="2023-09-13" version="1">MLSIFQPKNKGKKAESVHAPSNEHHAQVLHDQMPTIAQITTKLRLSFMAVAILDALGSPLQSEHRDQQRVIDEMLPHPTANHPAGYWTDDTSMMLCIAMAFASSEDPENCMALQIQTLREWKNRNYLSSTGVCFDLKSQVREAIDLYTSNDTNPDFALHLIRSQYGGSRDEVSGNASLSRILPIAFAFWSEPDIAKLQGRLSSEITHPSDLCKEVSQLFGHLIALILEYQNAPQKSRKFEDEPPMSKLTLLEEISKYPYIHERLRLMLTLPFGLERPQDTVELEQWYYQYHPLLKLITNTQTSGLSNSFPYAIPTSDDLPSTDFAYDTAVSALYCFFATSSFEHGALMAVNLCGEASAVGTVYASLAGVWYAGEEGDAEGVFWTKRMRQWKASTQKLDTVDAVARKMNKIVMGAFEGMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPQ0</accession>
    <name>A0A9P6JPQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LCCL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPQ0"/>
    <dbReference type="OrthoDB" id="425354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21639" checksum="AC18EC0B711A6262" modified="2023-09-13" version="1">MAAPADLTILNLSGKFYLNKTKTDATKMDEVLRLQGVSWMTRKIIGASSITLHIKHYKDDAGVEHIDIDQTLTGGISGTREERTLWWKEHEHEDHIFGSVLGKSRRVKADELDEPFLKTGWTADTLEHGLVQAYAESNTAKSNTTWIANQTWGLEEFEGERRYIRHLKFTGPGAEEIEVKFIYDYAGPLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPS9</accession>
    <name>A0A9P6JPS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_312750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPS9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040164637" evidence="3">
        <location>
            <begin position="22"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="12775" checksum="840755A004815AF6" modified="2023-09-13" version="1">MSSPTLLLLAVLASALPGSWGVFIIQQSTKCIDSATNQQVTCPPEDPAVVSARNHRRIVIICSTLGGIGFLILVASALTYWIQSRKSKHFDEETLPDDMSTANGYKPVSAKLPSDERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPV1</accession>
    <name>A0A9P6JPV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPV1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="261" mass="28974" checksum="07216E6718E634E7" modified="2023-09-13" version="1">MVSQPSTLLAQGRKKALKTSKGPKNPASKSRRVPGKMKHIPRDRIQHGVPLGVFIGDSATKSEPQPHHTENPFRMAENPTPHCDTDHSSISASPPLLPESEASHQEYFVSDTHSFDLKAAASLGPRSCSPRALHLPRFQNMRSELGPEMVHEEIKETDFNSFHAPLPSYDILSPKFIDQRQGPYPSNTAYTQPTVPQGNLFDTDTVPFSEYFGFSRGWDSMSNPRSFTQELAPERDAAAGIAQTMNDMFLDEPSNVYHGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ93</accession>
    <name>A0A9P6JQ93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ93"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="58948" checksum="C80BF3D2BC8153B1" modified="2023-09-13" version="1">MPAGKIVSLMERTNEPPNQVQRGWIEAKISELEEESALIDQKVADFMDVTQTQRDANRANHRRLTGLLTLLRKFPNEVLLEIFGHFLPSDRASILCVSQVSRLWRKLVVKTPSFWTDVYLPCPSRSSLENPSFKNIWDSFCFQFDRSQGQPMSLTIKITRLGLVTLFIDQLFAKSTSNRYRFRAISFHNFETGHIRKMLNYYEAYSEKASSLHSLNLFSPPGFRDASSVKVTLRDFMKLPSLSTVNLSWPYFDFGLSKDWTLLTSISLRVLDQSEPTRCLNHCPNLLFLDIDHSQGYGAEYTSETALVLQHLRSFSFKSRRQPSNLLNSLIAPKLEELVFVFPRREDDDPSLAKFLQRLDGRLLEFHCSGEVATRLFADSPHGGKDLNSLRNLKNLRIMAPFDESSSDELQDEPSIFRDLLHRDKSKSKFDKLETLEILDHPQLDYITAPHLADLLRSRCVSRFNASMVSLSNTGTLRRVVLTYHEERLDMDDLQHFTDNGLLKYYCDVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR49</accession>
    <name>A0A9P6JR49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_834956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR49"/>
    <dbReference type="OrthoDB" id="2621411at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="12175" checksum="C581B1160BCAE665" modified="2023-09-13" version="1">MEGIMFMEVDVEKESLELLEEQMFEMSKQAGVAGNRQWGLDAGSHQDDWNPYGGLPEHWDLQNYTAGDDECLEGPNYKAVEKIQPITQSGHKTRPKPKPRAKRAKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRG3</accession>
    <name>A0A9P6JRG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_248894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRG3"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37580" checksum="921886F488DD2DB5" modified="2023-09-13" version="1">MQKTSLSAPSWCPLGVLPVELWAEIFALSLSEDQFVTPNASNPPILLGRVCTEWRNIAYNTPDLWKTLALTSSDNVDHQSSVAGIETWLESSYTYPLSISLSIPQRSNAQLHKIVNRLLRTAQRWRHLKIDVENDTLDQILSTPMPSLYSIQLDCFNPLKKITISPFHLPSLRTISFFDPVCIDSRYILPWSQITDISSVGLANTETHMHRLRASPNLNSYDMTLFFADSPAMQEPFPLAGLKRLRIVAWVPDAIGSMLDNLVLPMLEELIIEVAQQICPCEPPPFPLEAFRSLVERSECLFQRLNVKNLRLPSELTCEFQNAHPSLKISVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRJ9</accession>
    <name>A0A9P6JRJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Afadin and alpha-actinin-binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_788332</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ADIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRJ9"/>
    <dbReference type="OrthoDB" id="312015at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052300">
        <property type="entry name" value="Adhesion_Centrosome_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021622">
        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46507">
        <property type="entry name" value="AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46507:SF4">
        <property type="entry name" value="SSX FAMILY MEMBER 2 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11559">
        <property type="entry name" value="ADIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="445"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="550"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="721"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="807"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="577"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="738"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="839" mass="91748" checksum="1C0D2715B67F1CDD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRS9</accession>
    <name>A0A9P6JRS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_851692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRS9"/>
    <dbReference type="OrthoDB" id="3219854at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="33"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="707" mass="79911" checksum="B1B1D561C1A78F0D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS47</accession>
    <name>A0A9P6JS47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS47"/>
    <dbReference type="OrthoDB" id="2945538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="63126" checksum="92EDB5B0A79125E4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSI8</accession>
    <name>A0A9P6JSI8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_763129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSI8"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF1">
        <property type="entry name" value="FILAMENT ORGANIZATION PROTEIN APP1-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040507128" description="Phosphatidate phosphatase APP1 catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="186"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="42139" checksum="27F644D30765D56A" modified="2023-09-13" version="1">MQLFKLAIISSFFAAPTLGAPVVEIAYSERGLIDGIHITDNLILFDAPAFPNPNNGSETLVDVETYAFSRIASFGSVIPVEVQLLVKALSALGVDAAQKVVQIEERVKLFLAIGLPAKSEHLKVDGCSNAPNTGATDLGPDLGLSDATLSLGKCDSGKQSAGSIGLDVLDTRTIANTIYFSPNSGFGVISDIDDTIKVSNVLDKAKLAEATLIDDPVAVAGMPQLYSSLAQSLPDPQFIYITGSPFQLYPFLNGFVKSSFAASAGPIWTRKLTLTNPSDLVSLIGGGDKTLDNKVSQIDRLHALYPNKKWLAIGDSTEKDPEVYATMYDVLSSSKYPDFIACIWIRKVDGAANNQTRFDTAFQGIPQEKTKVFTDQDISSLSSIRVANGECTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSK7</accession>
    <name>A0A9P6JSK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_848268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSK7"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="5">
        <location>
            <begin position="42"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="6">
        <location>
            <begin position="439"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="495" mass="53500" checksum="AE16ECD11EA44930" modified="2023-09-13" version="1">MRFCPTVSRSLRTGNAKTLGSRHFSSSRLLMDKFRVERDTFGELQVPSDRYWGAQTQRSLQNFDIGGPTERLPPPLIKAFGVLKKAASIVNVEYGMDPKIGEAIQKAADDVIAGKLVDHFPLVIFQTGSGTQSNMNANEVMSNRAIELLGGELGSKNPVHPNDHVNKSQSSNDTFPTVMHIAVVTEMSNSLLPALTELRDVLQEKSKAFEHIIKIGRTHLQDATPLTLGQEFSGYVQQLTNGIARVNDVLSRVRCLAQGGTAVGTGLNTKKGFDVKIAAEVSKLTGLDFVTAPNKFEALATHDALVEAHGALNVLACSFMKIANDIRYLGSGPRCGLGELALPENEPGSSIMPGKVNPTQCEALTMVAAQVMGNQTTVSIAGASGQFELNVFKPVIAKSVLQSIRLLSDGARSFTKNCVVGIQANEKRINTLLNESLMLATILNSHLGYDNVAKCAKKAHKEGTTLKEATVALGFLTPEEFDEKVRPELMLYPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSP5</accession>
    <name>A0A9P6JSP5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_850241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="2"/>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSP5"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="6">
        <location>
            <begin position="58"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="5">
        <location>
            <begin position="302"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="421" mass="47316" checksum="DBE45762C0967003" modified="2023-09-13" version="1">MSYLGDLLKNNLMANRPTRCKSAGDYIGQPIPPCGDSARSENTHIDLPPWYSKESSSLHRDIVVFMEYLEPTAKEKRLRADLVRRFTSLIESFGINATVCPVGSYVTGLYVPTSDIDMVLAFKQNLLSRNGYETSFYPLRNGLYDILQKIQKSGFARRVEDVLGASTPLLRIIDKKTGLQIDLTASDNHGINATNAVQKWMGDDTEKLIKTLVTVVKMFLSIRRCGTTYTGGINSYVLVWMVVAWVKLEWPKIRKNCMLQPSPEAELAAALRGLSIASGPSNSRVTAVGKLDKNLTRNVDFGYALRKFFKFYGFEFDYYHQAISIEPTPTYKSKPRAYGLHTYGGGQPYLLSIFDPANATEDMGKKAYAIKHIQASFKEAYELIIKLKRDTRSQTSSFSFLGTVLGGDFSYFVQERRALNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT28</accession>
    <name>A0A9P6JT28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_761305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT28"/>
    <dbReference type="OrthoDB" id="2747524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="495" mass="57576" checksum="AC51AA22C2C618D7" modified="2023-09-13" version="1">MSRLGSTCSELNIATRPNLFRDVRWPHRRLSKVDSPKALPFLPETTWSLIHDLHFDWPEEWPDMLTNPAETDHPDIFKRLDEALPKIPNLKVFSCTIPFDPPRRTLNILFEYTAVQHLRMIDTPLTKTPLLNEPHKVEALTLVPVAEAMRMGEGPFNGKMREMQYFSRPYRQQHRGVAMWFAGEIYLKDFRHVKYLQVSLQFVWHLGSLSSEPWPELETLILTGTCGAKNIGSMIDVVYTMPKLRDLRILLAKKIGHGPDDDRMSDHHIRKPTILSSIKSLSLSNSYGTEIFLRNASSVERLSISAILKHPQIPIGMKSSELDKALKDLEISGGNKSLKKIRLMTEDELTVAFFRKLGQLCPNLEFVEIERCGYQEGEVGFEWSDYGEVFSEYRYLQELRIGIPFADCEEDCTAHSDHKECIRSDRQDFAIHLASWVPTLLYVGFEYRTRTGKYRKEDRWLDYEIIRSSKRIHLTELAPTWYEIPEVWERTLLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT90</accession>
    <name>A0A9P6JT90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT90"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="364" mass="37903" checksum="80230527CBD8A037" modified="2023-09-13" version="1">MSTVCSSTPTLTRTILDTTGLTSVSTAVSTITSRLDAITTTISTCIATGTGSSASCVPTQIVETLDGTGVALITTTIEITAIIDKVVTNTETLYSQACSVGNKPVPPPADISTSRRPADISTPAPTPIITTISGTKTTVYPSNTALGSSSSGSSSKKFPVGAVVGGVVGGLVLVGVIAFFGYKFFAKKMAIKRLNNMLDEDNDADVKPYGADLSSHTPPVLPHSQEPSNATTLGGQHQSYQAASPEMQQYPLTQQQSPNQPGQQGYQYQGSPEAFQSQNNRPTSGQYVPPVSTGSPPPSQAPYLTPNGGYPQQQQQNYATNTAPSPPPVHGMVYNPNLGYAPPPPNQYPNGYQGYAEPSQGPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV75</accession>
    <name>A0A9P6JV75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_902186</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV75"/>
    <dbReference type="OrthoDB" id="3053196at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="11">
        <location>
            <begin position="161"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="404" mass="47506" checksum="73700E79E96C74E8" modified="2023-09-13" version="1">MASKRRKSSAGISLDPTAMIDDKTHHLVGPFLPQTPLSSGFSSPERSPSPTLTKPPPSIFLRWAIEPGSALKLLLVPVALYINWELVAPFIETKISNPFGNLFLLTGFIPDSKPDDPRYQKTWWDIGFLIYYVVFFSFARQALLFYVSRPLAKYFKLKRTSKMDRFGEQMYAMIYFIIMGLWGFRIMKSLPTYWYNTLEFWHGYPHWDMTRELKCYYLMQFSYWLQQLLVLILGLEKPRKDFKELVAHHFITLYLVGGSYIMNCTLIGNAVFMSMDLPDAFLAFSKLLNYIQWNNAKVYAFIVFFGVWTYFRHYLSIKIMWSVWIEQPIAVPEGAKVWSFENGTYLVDWVRYQMFLPLILLQFLNLFWYSLMVKILVRAVLHNEADDNRSDDEGDDEPPKPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVC5</accession>
    <name>A0A9P6JVC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVC5"/>
    <dbReference type="OrthoDB" id="3355886at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="21596" checksum="4D678D9384A46792" modified="2023-09-13" version="1">MSFRVSSNILRAASKRPIGQQSRPFHSPFAVLGNSPLTSPPPPEHQSNISSAYEKHYDHAPEPVAHTGYRTYVVSEPDAHSRHYQVPAGAYPTSAPYVNFTATSAPDVTGFQYSSTSGELRAHEVTSRAAAQHAKGVGESSAVRNASSPGAMGVRGGGYGGLAMMDKKGTTTTGSQLADRNPPPDGAAAEKYSKAGVDGAWKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW22</accession>
    <name>A0A9P6JW22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW22"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="7660" checksum="0205E813514D229F" modified="2023-09-13" version="1">MSGSSLGPDRVRRQRTSSTLYAKAATNIPAYTRSGFQNHPLSAGGYTRSGSMPNFRKPTRAPRFKGKEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E0Z8</accession>
    <name>A0A9P6E0Z8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158177">
        <property type="protein sequence ID" value="KAF9521272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E0Z8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="15733" checksum="76E0E3038E0F161A" modified="2023-09-13" version="1">MNFLYQLSISASQVPRSSLWSRTSIRLKIEHSLATLGGSALGNTTTEMKVSFVVTRSRYSPSATDRRRHLTLRAFDSPGRYIGAVHTFEDIRTPATYVPLKLEPQGNKSKRAKKNKKNKKEKKDWRGVWLQDVDAVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2L9</accession>
    <name>A0A9P6E2L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_935012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158219">
        <property type="protein sequence ID" value="KAF9521243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2L9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="46739" checksum="FD0A893084581899" modified="2023-09-13" version="1" fragment="single">MNHSLKGSLVLLIAENDVVFSQADTPDDSLRLLLGELAGKDNERAYQMLAAHRQGHAISRNKTDCLFKDRELLQTFAEPYCFKGLCQEKLWKASTLKSWAPFAASLLTPYVTHQMGTLRYLASYDSYEKFDSTILEIQISTRPYSKDLQKRMEKMVARSMNIAENEINYSIQILDRDFFDILDKLYMEHLRTAITAYGLDPAHFDELNVHLQIPRERSEDEDGSDGNEEDENSNEDAMDEDDPKGKRKAGAKLPKILKKIQWERNFQSYMKDLQQKINIWVQDKIAASSSLHEDSTINILNQISKKMMFLVHANAYQAEDNLPVITQPPPFFTRLFLYDLGKDLVDAEQGAMLAFSICDPLIPYNFNHKKTKQIGEYFIIPKLSTLFEQWLMVRGVMEKSGPIVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E312</accession>
    <name>A0A9P6E312_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158020">
        <property type="protein sequence ID" value="KAF9521587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E312"/>
    <dbReference type="OrthoDB" id="2675946at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="466" mass="51379" checksum="B22E182DE6ECFFF2" modified="2023-09-13" version="1">MSRPDERQLTPLPPSTCGEPNNFDYSKNPLIRDHDVTSTQRGRMDSQAKFSRLPNNKNPTGFSTEENQTYPIPQRPNPLDRPDPASHSLPHDSWPVLADSPTSVGTQRPLVMAQANNYVNGPTSQDPLPPTNNPKASGTEDVFPPAPMTSLENNAAVTAGNLDEYDEDESEGQDLEDDETFRHHRTKGIFNAAQWLEDNRGRGTRRAQASLVKFCFGITGRKEDPQYLSGSTFTLVIHATVNPTYTCFDPYRNPEMCPVGALALHMHFVHDTLMLEDFLNIDYTAIRAGATSVQLLHGPSPTVPYNESVTNIADCLAVNDERVASSSLRSSSPPGDILLPSCCPTRRALNQLSSLTPAKTIVLGGDSPCNGPDAKDLQSEYEELLLPLDWQRKTVLASSFSEDSDPDDGLAPSPFSSPEPNTPGNVDEEQRTRPLYFSSPPQSNLPEYQQLDEYPSHHLYHNSPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3A0</accession>
    <name>A0A9P6E3A0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157995">
        <property type="protein sequence ID" value="KAF9521722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3A0"/>
    <dbReference type="OrthoDB" id="2978595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="306" mass="34473" checksum="2555A31BD84443C7" modified="2023-09-13" version="1">MLLQSASQTDLMKANSDGCGSIDAFEPMLIEAALRLPTLNLGSLIFGTEAWKRLSSSAGLPLSSLDENNPLAKHFKRIRPLSKMNVPPPTHLKLDAYEDLFLERNDRSLAMRHMSPFLYRTTYVAKVRDVWSLHDHPWRHHVLTMVTDPKEKAKHYLDNITQHSNIMTVGPLDFSGTARVVNGRGGNIVLMCENDPCVQQFYVLRRQFQKATVVLKGKGEEKSGIEITKKRRIERRVIEIRQSSSSTTTSPSSSTASSPSPEVGGETEERPVKRLRRSADRDLTLISQLSPLANSLHLGRTLRHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3B7</accession>
    <name>A0A9P6E3B7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157994">
        <property type="protein sequence ID" value="KAF9521742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3B7"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16525" checksum="089A4FE4F17ED3CC" modified="2023-09-13" version="1">MEISSYSQRTPRSVPQNCELNAGTPCNACTSLAKIDTDKTSHVELDALRRDTVPKINARHDPMAYHLPVELSAMIFWQCLPVLPPPQSFDQADDGLDSQLAQVTHSLASVNQNWRNIACSTPKLWNSIFSTSRKTYSARRILYWLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3L9</accession>
    <name>A0A9P6E3L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157974">
        <property type="protein sequence ID" value="KAF9521918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3L9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="419" mass="47588" checksum="3FD01036E89B8D1A" modified="2023-09-13" version="1">MQIIPNELLAEIQAYCDCRTSLNFLLINSEDQTQRRRQLWTHQDSLGPLLELLPASLWTRAPNRGQHRCRHCKNLKKKTFNASTMTLDINAIRQVTMLAGVMSNLVIPSKERCPLIARIATDAMGFIHKEFGGPILCLRSISCWETNDDSRHGPCSASQEELLFQRVLTVCHLDTVECLDVPGVFPNTGDWVAKILEWTGSALKELRISDPPSSTQLWRNTERWTNLTTLIILEDSCNISVLYRHIAQLVSLQTFCININTHSSQDFGSTATIHWPALTKIEFCSPDGPLEEFLALFETPSLQVVKYKPSFGVDGTLMNAIFRASSVLVSIAVTIFDPESMFTPEDTLWSTLEPIDDEDVEPLFRLHTLRELRLDGIFTSEVTEEQIRKLRQQNPSDLLQFEALVGWQGIESDYEEYDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3M3</accession>
    <name>A0A9P6E3M3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_840861</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157973">
        <property type="protein sequence ID" value="KAF9521924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3M3"/>
    <dbReference type="OrthoDB" id="3068150at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="33"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9521924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="39138" checksum="930B24E656D11923" modified="2023-09-13" version="1">MSSLEEGELPRVEVKKFMSTQSCRSGDIINELFELITIVGKGASGTVWSAWTIRPDSLDRRQVAVKICTNTVAHAKDNIQQMARKIATINAKEKQDCFVSDLFAGTLRDILLGEDLIPSQQVREIAWQIFAGLDFLHELDVVHSDIKPENIALTNVEMLAVQELDKTGKFVTKFILKNPRIKIIDFDEARASHHKWWNPVSTVQYQAPEIICANPFRIDTGWTEAVDVFAGACVVDELQTGRPFLPPTDNISLVLAYLEQSIGRISRGFAHEVHLVHPSTTSKIDPWRFLLPATIPDGKERSYKQVSKAHPLWMVIQRADLVDLLRKTLYADPIGCLTAAGALRHGYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3P6</accession>
    <name>A0A9P6E3P6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157973">
        <property type="protein sequence ID" value="KAF9521932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3P6"/>
    <dbReference type="OrthoDB" id="3121424at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="29757" checksum="5D2CA96E22806262" modified="2023-09-13" version="1">MAEESKIQGCLVEVAYPVDSKGIAIKPKDLARHVDETYFPKPQCFHGLPASLAVANPGVSGEPNVILICSVLDGYNLPCSFFINATNLLRTSSFIRYIHYQKRPVWVLPPDGTFAVPVVESMKRGVMRAHADLFPNSQERPEGCSLNCVVPDAFKQKLAEPLSLLPLQEMTIPKCHRVSMSGEVGSQDDNEENISTIGTVSNRHPAMLLLESISSSYSSIPPLEAVSFSLESTDDRVPATHLPPFLSLGPESRTGKLSSPVVFAVPREISQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3S6</accession>
    <name>A0A9P6E3S6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157966">
        <property type="protein sequence ID" value="KAF9522014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3S6"/>
    <dbReference type="OrthoDB" id="3054009at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="25005" checksum="E2216FE31721CCE0" modified="2023-09-13" version="1">MAHVEEVICEHQPLTRRLMLGIVKGQDAGGSRLRRPAKIVRLHPYHLARNTEARLVPLARGLLAFAYFAPVDLIFYSSLTAEMPAYSSIVSACEATTKTSRLQLPVKPTKVHPLSASGKNKTITAELKDALLNIRPQQGFAGAVVVAPGDAGEMASAGSAGGVSRACARSAGTSRGGGSRARPVSADGAGEAVGGLCGEGVNVDDGGGGAGGGGIAGGYAEVAVMVTVDVLVVDDDDEEEQEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3V2</accession>
    <name>A0A9P6E3V2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157970">
        <property type="protein sequence ID" value="KAF9521968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3V2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="11240" checksum="869250E889B32512" modified="2023-09-13" version="1">MRLVLVVLRCHYAPPDSMFLSLTTSASVSPQPLAHKAVIVAATIGVADAIHCRNISDTTPLLNGVERRGVRSSEQGGEEDESEFHIDERDFARCVEKTSWFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E487</accession>
    <name>A0A9P6E487_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157953">
        <property type="protein sequence ID" value="KAF9522278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E487"/>
    <dbReference type="OrthoDB" id="3267861at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="8259" checksum="37ABD32633D678A2" modified="2023-09-13" version="1">MPAKRSFESNSNAGYSRSGGNTERSDELGSMTRSNSESEPASLPSSEAGEVVEHISVGTVEWQNRGTLHVHLLIWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4D7</accession>
    <name>A0A9P6E4D7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_744977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4D7"/>
    <dbReference type="OrthoDB" id="3267098at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="171" mass="19723" checksum="05424863449E8DC3" modified="2023-09-13" version="1" fragment="single">NLNEAVIIQDNCLFSHVTAQFNFTTYDVRRDQDTINTNNMRRDIMVPSFEDCEDEDSQWQPYWYARVLNIYHANIHFHGRPKAEKIELLWVRWFGKDPDSAGGPSILRLNRVGFVPASDAEAFGFLDPALVLRACHLIPAFNSGRTLNLLGPSFARDVGPQGDWEKYYVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4J5</accession>
    <name>A0A9P6E4J5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_911377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4J5"/>
    <dbReference type="OrthoDB" id="5424209at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="38126" checksum="ADF9994ECC51D07E" modified="2023-09-13" version="1">MPYIPVDSLSDVVYRLVVDQYDPPPDYQLGFWATLPLTVGVLPNTLTGEKAFHSSHDILNLLKEHGIFNIDAAYRESVVRGFSGPELFAPVSNSNPLKNVINPVTTALGLPIAGLQTLKSPGTMGFYFKVSDVLYGVTAHHVLFPEDQGNNEYSYVVGPKKKVILMGTRAFTNFLISIWGNIGTLNDTVSFLEQSITTLIPSLDTSCPNTELAETQLRLGITQTAIEELKRFYLMIKKQWSKPRDRIIGHVIWAPPISVCTTSPSYTKDVCVVKLDEKKILTKLEGKCPEIDTLTLISLLYSHTDDPSDFTDVLDRLLELRGILSAQEICTSDKKDAMATPCDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4N1</accession>
    <name>A0A9P6E4N1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_115534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4N1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="235" mass="24658" checksum="1E2DCDB1310F39A6" modified="2023-09-13" version="1">MEYGHRNVPIPPSLPMHGLGAQGGGQGLPISNVSNMRETKRTRLGVHPPHSRSPSDDPVNGAYHYPTHNSAGAFGSTRHGAAGYHPSQNQQHHQSNSPYGFLPPSNSPPAFDLPQGGIGLSSRGQGYGLPHRTGSSGPGPYDTPGNYGNMMGRGGIPANGGENLFPGLQQGGFPGIEWPVHGGGNPGPNSNAPLPNPGIIFFRFSPRTAYLNRCSSTRISTLTTTRDTGHIGSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4U5</accession>
    <name>A0A9P6E4U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157945">
        <property type="protein sequence ID" value="KAF9522444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4U5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20362" checksum="FDB3D74BF2F8C46B" modified="2023-09-13" version="1">MSAIVPARILTASTLLHYNTDRDGTICLRYSYDAPGSSDSRLRYHVVRWKLSTRDESPLVRIKSAEVHREAPGEVFDLGLTLHGFKSNVRSRRFAQFFNGPRPYEFVHHIYGEPDQWHVIPRSPLTSGGRHLLFYILAAGACTLQVEITVASLDDDPSLPEDNGPEDSSSSEDGSSSSTEGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E529</accession>
    <name>A0A9P6E529_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_91202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E529"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="97"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="160" mass="17746" checksum="1F957F25953B9CC1" modified="2023-09-13" version="1">MPPRKSTRIVGKTSADASVSAKLGPKKRKLKSSKKPIVFYFAYGDTRLDLAKGYYPLYLGRDPLLQPVVYELAEEADATLHIESDDQTPADLVSAVPNVFSELPTELLVEILLLLGPRDLLYLTRATKYLRKLLSSDSDNVANIWKEVCALDLFVLFGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E563</accession>
    <name>A0A9P6E563_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_864184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E563"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040547607" description="Hydrophobin" evidence="7">
        <location>
            <begin position="19"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="105" mass="10270" checksum="A46CC0438443F798" modified="2023-09-13" version="1">MQFKSLAVIILGASLAAATAIPASQCNTGPVQCCDSTGTAKDPSISKLLGLLNINVSDVDALVGVTCTPITVIGAGGSSCAAQPVCCSNNSFKGVVAIGCTPVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E603</accession>
    <name>A0A9P6E603_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_910824</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E603"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07135">
        <property type="entry name" value="ALDH_F14-YMR110C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="471" mass="51647" checksum="F360492932E7E106" modified="2023-09-13" version="1">MASYTPLDEIPKIHAELRETFRSGITKPIAWRRHQLHQLARLAQENADEIADCLYKDLGRPKQESIFADICTTIELSLLAASKLEEWTTHGEPPVQPWQQSWKPRVEKHPKGVGLIIAPWNFPVSTALQPVYGAIAAGCCAAIKPSELTPHSAAFLAKTIPKYLEPSAYKVILGAVPEITKALELKWDHIFYTGNGRVGRIVSAAAAKHLTPVTLELGGKSPVLVDSTADLDLTAKRVLWGKVVNAGQICVAPDYILAEKDVVPQLVNALKKHGQDFYPNGALTSDSFGKIVSDAHFKRLTELLQRTKGKVVFGGQSDEKTRGIEPTVVVVEEGDVLLEDEIFGPILPVLAVESVDAALHYLKDRDYPLVLYGFSNSDANKQKILDATTSGAVAFGDTIQHLSIHGAPFGGVGESGHGSQSLQYTFDAFSYMRPVVDIPFQDEQFFGARYPPYTEKSLEFFSALLKIPIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E708</accession>
    <name>A0A9P6E708_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E708"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="7022" checksum="611B72CB6838C8C5" modified="2023-09-13" version="1">MWSPTGPQRYIGVTIFFTPDNPLLLPAPILLSFLVALSLSFHQAGLIYNLPCCPGMPRAWLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E791</accession>
    <name>A0A9P6E791_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_820998</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E791"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048761">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21138">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="234"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="465"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="468"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9523770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="771" mass="84086" checksum="DD330C0F42677396" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7J7</accession>
    <name>A0A9P6E7J7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_646794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7J7"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040231801" evidence="1">
        <location>
            <begin position="21"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="28213" checksum="AD800FBC616A2288" modified="2023-09-13" version="1">MKAFLSILALCLACITSSLAVPTTSSVDVGQGCVEPSLANPLKTIQLQRRHELELEKRQFQLIPIAVGLWLSIAAESAAEPIIDAVAKSLNAVFGKDPTPWDGGADKCTISYSTHGGAQCQATINAKGVKSARPSNNWNVCPWINPASTAPPIQYFSDKGLGDYSIQFTATDKVAWADIPGTEKCIMEGLCNPRITFYRKDHSIILDTWMSLGDPTQGQYFGDFGGLCGNGPIKNQFKSNGMVMGYDCGVPCEGATDIPSTEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E848</accession>
    <name>A0A9P6E848_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_861875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E848"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="73"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="14336" checksum="985DF072067B1778" modified="2023-09-13" version="1">MATLSDDTLRKILAQIQQTAVQSQRALNISQQQTASKDRERRILQLTIDEISQMTGEVNLYKGVGKMFMHVPRKEMEEDLKVQEKELSDDITNLNKKSKFLEKQFNDAQNQMRDIFQHAPRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8G3</accession>
    <name>A0A9P6E8G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8G3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="39293" checksum="34074E70AE18EA24" modified="2023-09-13" version="1">MSDFELGLVFFIRDDDPLWEDELDMFQIRDSFLSMYSPITHRQSTYKAFACSVFETWSDYLTCAYFSVTSNWIAVAAISLPFADEPFRASGLPMLAGVHSRLVNPTHPFPYTLNLTRFSATLTSEITDPKLPWFEYESVTYQKCGLEFHHSDEFFAEWMLDTTNGDIPDRWKRSWFAGKIRSDVAAMRVWGCALERHHVSGWISTFDEMRDFFTVRSIGRHMGLVPIAECNVIELGQGFLTASVCRFLCRFIFGSGQWVTSWLGVYLRDKSVRGDSSYRRKAPHLKAGITGNLEDDLVEEEWVDSFLLGVDSEDDLEVDEDTVMGDTSQNEMDTSSGSEAETLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8T3</accession>
    <name>A0A9P6E8T3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8T3"/>
    <dbReference type="OrthoDB" id="2662373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="395" mass="45216" checksum="01265A819DAD4BE4" modified="2023-09-13" version="1">MSFPKVVALDTDWTIWQGFLNPALLGKGPGATPKLEDNIARVDRSVLQDGTNHANFVRVCDDVSKIINDILKNGAKLAIVSRNPSKAVCDRALYYYNTINPKDEKEWSIIDMVAYDEVVDGKSSYFFEVMFDDEAFNNVVKVELGTAFQLVRDKLGMTWDVYQQGIDAWRRAKNITIPPHMGGVPNRRLIGYTGLNRPWIDLVQRKEGIVDTTAYYRWGYGLYVADNLGIAKMYNSMERDLGFEAHVCAVYVNDYDIWTRMNKIWVPENTGNPAQMMNRTWSAEETGKNQEDRDAFIAAQWGVRTPYALFSRHFWFNKLPLPQGQRWNEMLLSTQIVRALIDITLLSDAEVDQILSAGISPIFQNSIKEWHTTVPNETRQEFLTRGETDLYQLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E911</accession>
    <name>A0A9P6E911_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase GET3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_819832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E911"/>
    <dbReference type="OrthoDB" id="1770at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000235">
        <property type="entry name" value="ATPase ASNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="9">
        <location>
            <begin position="24"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="36080" checksum="CC12E11AE39E85FB" modified="2023-09-13" version="1">MSELLPPTLQNILDQPSLKWIFCGKTTTSCSLAIQLAQVRESVLLISTDPAHNLSDAFGQKFSKDATKVNGFDNLYAMEIDPTSAIQEMVEQCTSDSNGMMGSMMQDLAFAIPGVDEAMSFAEIMKHVKSMEYSVIVFDTAPTGHTLRFLSFPTVLEKALGKLSTLGSRFGPMISQMSAMMGGEASSQEDMFAKLENMRAVITEVNTQFKDPEKTTFVCVCISEFLSLYETERLIQELTSYEIDTHNIVVNQLLFPRQSSNCEHCSVRNKMQQKYLNEAHELYDEFFHIVQLPLLTEEVRGPEKLKSFSNMLVEPYIPPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9C1</accession>
    <name>A0A9P6E9C1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_860056</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9C1"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="12">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="155"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9525128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="953" mass="106085" checksum="3B51F4C82819D78E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9K0</accession>
    <name>A0A9P6E9K0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9K0"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="12"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="404" mass="44165" checksum="54BCC63EB5DB001E" modified="2023-09-13" version="1">MPSLSSAGKTALDNAIKDAVARGRVPCVVLGITGVDDDIYLQSAGKNIVGDPNSGDVNADSVFWICSQTKMIVSLAALKLIDQGKITFETAVADYLPEFRNPIVLDDSTNLKSTYVPAKTKVTVKHLMTHTSGLFNRGSSARLSVSEAYASKETHTSQNPVTSYFKILTGDFPALPLKFEPGTDFAYGYSSDALGFVVEKVSGQTLEEFCQENIFKSLGMNSTSFYLTDDLRSRLINLAHRKENGDLEPWADQCELPERDPIKVRLFLGGIGLFSSTRDYLKLLRHILQINAGREVSNPLLSIDTLKTIFTPLLNEEAAKTLSQFTMTKGVQFSTALAVTTTDMHNLRKKGSGGWGGWASSYHFIDPTAEIAYAFTTQIAPPGDKDAMMLTLGLEKLVYTNLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Q2</accession>
    <name>A0A9P6E9Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dehydrogenase E1 and transketolase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_565510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Q2"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="5">
        <location>
            <begin position="659"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1014" mass="113037" checksum="C7B6D934D20F38CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA10</accession>
    <name>A0A9P6EA10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA10"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="379" mass="40611" checksum="18C157FCA76B83CA" modified="2023-09-13" version="1">MGSISYAYNGPLPDFAHQRLEQAALLVSRCAQSSERSIGINWRRLGSSIISEHYHVEYPGLSNQQIAIQETLDEVIRKVVNRQLDLSRLDSSALQGTLEEILSDILDCMVHDAVASSSDNSDGGSGPDSSDEEDDDDDDGDGDNASDAAPERGSNGFQGHDSIQSDRYHRPNDSGSGSDSDSDSGPESGGVWRHQQHQHPHRQNHQYRHEAANDHYSRSSSQDSSYRHDVRRSRGGFITIKRRKGRIPSPTPSALTDQTPRGGVGPQAVASGPVSPGTAQNLPPSLPPSSSFGHASDDGLLQQRPTEEDLGTYDEYQETVISISQATPAFATLVSSVTNAEGPRRRGAAASLEAALGPISSHPEEAKANDGGSTCCSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA56</accession>
    <name>A0A9P6EA56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_558952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA56"/>
    <dbReference type="OrthoDB" id="3234297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="38889" checksum="FCF8E37AEAB37F30" modified="2023-09-13" version="1">MLIAYSTVEKRRRSIYINLLSQQALIILSIWLSLRRNQLSVSDIQFAIIQTRSPVSVYALLLLIPRLFFEMSATTKASTGNDKPPGSKSDTLLERYYSSRTFDWALITRQLWGGLYGFSCLGINLLGTSDKLGYALTYQSQPGQKLDLENPISIRQSKGSLSSITAWFALGVCSLVVYECVISRHAEERREVMHELSGKRKKSMKAWPISARIRWGFVATWFIVMKFHPWLPFVYASIFFLNWSMDMRIWTIEDKFDWTYGQVLAISQAVVVVYPCLTLLFNSRNDIVHLPQRLFFDILWLVSEFLERLSARSRLNREACSSPCRRCLCSQFYLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA58</accession>
    <name>A0A9P6EA58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Pre-mRNA-splicing factor SYF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_772451</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">May be part of a spliceosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SYF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA58"/>
    <dbReference type="OrthoDB" id="199717at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="332" mass="37397" checksum="0652801B222E40DC" modified="2023-09-13" version="1">METDESLVESSSSVIQATSDAVANAEAAVSEVAVSVKETVGHVVEAAGEFVEEMTMTGVEGPSQNPTPTNDEVKQSESEKETQKLTMEERKAKFNELRKKMAASTKANRTSLVEESAKAKVTARDAARLDRQRKLAETLRTKADAEERGEDVERQKNWDYTIEENDEWEKKLARKKRRADFAFHDDSHAARRKYKKDLDFIKPDLEAYNKQKALAMSQGGSSLSTFSSVSGSSELTAASEEQRMASENLYRDANTLIYGDSKPSEDAIDRVVSKMNNDIDKKSKFSRKRPNDDEGDITYINEHNRVFNKKIARYYDKYTAEIRASFERGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB00</accession>
    <name>A0A9P6EB00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glyoxylate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_896787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB00"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05301">
        <property type="entry name" value="GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF277">
        <property type="entry name" value="GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="23"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="131"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="39524" checksum="3829C786A4148ADC" modified="2023-09-13" version="1">MSSSLSNRLSHIFSHLNSERLKIVVTRDLGPDVMTILYSESAKYEIVLWPGKNACDRKWLLDNVRDALALIVLVTDRIDAEVLDAAGSQLKVVSTMSVGYEHISVPDLAKRNIRLGYTPDVLTDAVADISIMLALMAGRLAKETTLFVSEGNWPTYSWAPFAFCGSQISATPSSPKRTAGFLGFGRIAQATLRRLLGFGFTHCVYTSNPFSKPSPERDSELLSSFGAPLHSLKRVSLDELASESDVLFVLTPGGDETKGLINEAFLKKMKKTAVLVNSSRGTVVDSDALAKALKEGWIWGAGLDVIAGEPNVAGDHALVREPRCVVLPHIGSATVQTRLDMATLAVQNALAALNDQDMPASVNVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECG5</accession>
    <name>A0A9P6ECG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECG5"/>
    <dbReference type="OrthoDB" id="2867594at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="14248" checksum="4CCD1C4BAD42BE63" modified="2023-09-13" version="1">MSIAVFFTCDIPEKTLNRFLDAGQVYLDNSHCDFASDTSDIIYLLIATVTSKDYDEYPTRTTRPFRPFHSPFIGETPEQVASWFRGASDPFDVERSYPLVKSFIILDEQTAKDNQSCLLHQLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDB5</accession>
    <name>A0A9P6EDB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="3">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_856867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="3"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000011">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000012">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000014">
        <property type="entry name" value="Phosphatidylinositol 4-kinase STT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="9">
        <location>
            <begin position="1378"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="1665"/>
            <end position="1930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1947" mass="218402" checksum="FA1D7414A2ABC274" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDI5</accession>
    <name>A0A9P6EDI5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDI5"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="146" mass="16003" checksum="1A4AE86F5ED08168" modified="2023-09-13" version="1">MLTTSCSPPPAKDWSMQGMERVGCKVLERGYWKSGEDKRAEIKVLNQGEGADENGGIVEEDGTIEDNDNDNGDGGYYEGQHANKSNGRKGGLSQEASGSSEMVRLKRLLSHFSRTIFEQLLLLPKCIANAPKSLNMIAVYSVLYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDI7</accession>
    <name>A0A9P6EDI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_446859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDI7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040331434" evidence="2">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="147" mass="16034" checksum="8026C9716D4593F7" modified="2023-09-13" version="1">MVGILMLVVILVGACSMGRSVKSLKPPVPPHLSSRHNNSNHQLQLQQVTAGFPRIFPSNDPPPCSKPEPSKYTPSRCTHPTCTPPTSTSTPSTRTPSRCGPSSVQRDKLFGKLNEFLLYIEGIATSANLKKPMNLESLKPRSMLLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEJ3</accession>
    <name>A0A9P6EEJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NUDIX hydrolase domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_767527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEJ3"/>
    <dbReference type="OrthoDB" id="10260614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015938">
        <property type="term" value="P:coenzyme A catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034654">
        <property type="term" value="P:nucleobase-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090407">
        <property type="term" value="P:organophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000036">
        <property type="entry name" value="Nudix hydrolase 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF45">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="59"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="36220" checksum="69C6C9E388F7077B" modified="2023-09-13" version="1">MAPESRNSIPRTTNLLRYHRPKIHWNEARIPPLSQESKRCLRNLVLYRTPRQRIPYPRSRSAAVLVALFVGRHGDLYVLLSRRSATLRTYAGDTSLPGGKWDPEDRDLEDTARREAYEEIGLPRDRNKVPLLCILEPFLAAELIVTPVVVLILDNTLRPILNTAEVASLFSHPLESFLSSEPPFPFEPETLEVPYHTSWIVKGSGPPDQTFMVHRFLTGREAGGVKPVLGLTAGMLIRVSSIGYARLADFEVQPPRSVSTDERIAFALLNRKVFRDAAEKENVDLEASRRLVAKGIKREERWREKEISRNTLRTRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFG8</accession>
    <name>A0A9P6EFG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFG8"/>
    <dbReference type="OrthoDB" id="3168860at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21933" checksum="A40826186BF5F8A5" modified="2023-09-13" version="1">MMANLDRDGPWILYQYGDDSQKHRYLDQESKLAFTLQEFQQNEDPNRVIRLVRDGEWSARYPSVMGPDRSYFFMGPENNLGYIVFGNGNIHIPMGYMLRGGKKEGSVSRYWRGQNGNQYKWKATNYRMECLDNGRTLALWEVSPPDKNYYATLTIFPKAMPIITEVLTSLILNQMALALTWHIPSHPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG60</accession>
    <name>A0A9P6EG60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Queuine tRNA-ribosyltransferase catalytic subunit 1</fullName>
            <ecNumber evidence="6">2.4.2.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_766637</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:16633"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:18571"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="EC" id="2.4.2.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="6"/>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG60"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="6">
        <location>
            <begin position="247"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="6">
        <location>
            <begin position="271"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="413" mass="44993" checksum="03BFA454B9A5B218" modified="2023-09-13" version="1">MEFEVIAKCKTTKARVSRMKLAHGVTMLPTFMPVATQAAIKGLTSQQMESLGVTLILNNTYHLNLRPGLDVLKTAGGAHRFQGWNRNLLTDSGGFQLVSLSKFTTITEEGALFASPFTGEPTMLTPEESISIQHTIGADIIMQLDDVVSSLTTGPRVEEAMERSVRWLDRCIAQHNKSGKKDSQNLFAIVQGGLNPHLRDRCLDMMVARKDGVAGYAIGGLSGGEEKGDIKQCADKLPDERPRYSMGIGFAEDLLVCVALGVDMADCVFPTRTARFGVALTHSGPLNLRLSKHTKDFGPIDDSCPCPTCKDKVSRAILHHTITHETAAAHAITMHNVVFQAQVMGRAREAIIAGTFPDYLQTFFAQYFGKAGYPEWCVNALRSVGVDLLEGNPNQKVIPGTGAKWEYSDNPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGG6</accession>
    <name>A0A9P6EGG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_853265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGG6"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="8552" checksum="0957468E30C650B6" modified="2023-09-13" version="1">MSSFADSSFEQYDPSMPQAGLSRSTKRTPMACSFCRGRKLKCDGKRPSCTNCDKRILACVYQPVNPPPEATDKSRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGQ7</accession>
    <name>A0A9P6EGQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGQ7"/>
    <dbReference type="OrthoDB" id="2674421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="36394" checksum="0C0DE298B010FCB4" modified="2023-09-13" version="1">MAAQDGQNTAEYLFFPITPIKASRFTPIKRGSGTDSTGNPWPERPNQDALPAGPRAHWGQFSNLSANHVLYDCELINPHGWIRLIHPDGKSYYMSLQGHRNPSIVTELDISVEATQTTILRVHTELCNQLLSLGWMPKSIGQEEVYIQMAGNTCSYYFVDIRSQDIFWAHPFLREKLGEGFPSNPNYDRIITQNYFAHLESFPCGRNAYDQNLDLSSTFKLRDLLRLAISNDPNTPKSTVLDYLVAVQSPWVEADPRTYLEVLDDLKKEKFAYDGTLDENWVWFVSRLLRLIYHEQNTHRYGMPNARPLWNLQRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHX4</accession>
    <name>A0A9P6EHX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucooligosaccharide oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_852631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHX4"/>
    <dbReference type="OrthoDB" id="407275at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040433592" evidence="6">
        <location>
            <begin position="20"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="52"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="493" mass="52200" checksum="AD9ED9126093C57A" modified="2023-09-13" version="1">MGFFKQSILALLTIAVIVGADIISDLQGHGFEVAVPGSDRYNSASSAYNLRLDSVDPTAITFPQSPDDVSEILKVCTQNGIAAVARSGGHSYVANGLGGQSGAVVVDLGNFKVISVDDNSKVATIGTGNRLGAVASGLNDKGRALPHGTCKMVGIGGHSAFGGYGFTSRKWGLTLDTIQGLDVVLSNGTIASVDANNYPDLFWAFRGAGASFGVVTQIHAATQDVPPSATVFSYTWDLSPEEASKALGAFQSHAQGQNLPQEYGAEITFGKGSAQGRVSFALVGGWYGAQDQLQAVIQPLLDQIPGQPNAQVTPGSYIDSVVTLDGSGSLDTSDVAADHDTFFARSLTVPQSVGLTDTARTAFTNFLSQNVNSPTSWFCQVELYGGTNSAINNVPFDATSYGHRDAIFVLQLYSYTSQPPFPQSGFDFVNGVVDSIVNNSPAGTDFGAYANYIESDLPNWQEKYYGAHYPKLQQLKKQYNPTNTFRFPTSIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIB4</accession>
    <name>A0A9P6EIB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Allantoicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_852839</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the allantoicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIB4"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004037">
        <property type="term" value="F:allantoicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000059">
        <property type="entry name" value="Probable allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00813">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02961">
        <property type="entry name" value="allantoicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="ALLANTOICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045:SF3">
        <property type="entry name" value="INACTIVE ALLANTOICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="7">
        <location>
            <begin position="27"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="7">
        <location>
            <begin position="193"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="550" mass="60287" checksum="5EAC5A970F65E0F0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJL0</accession>
    <name>A0A9P6EJL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_145009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJL0"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="56706" checksum="25835FD1484EFEB5" modified="2023-09-13" version="1">MVRFSGILAALATATTLLTPIVTAKSTLRKEELRARQLEAVKRWQPVKRDVQATQNITFSNPKASEFYVDGKSIPEVDFDVGPSWAGLLPISANANETRKLFFWFFPPAQGGSLDDMIFWTNGGPGCSSLEGFLQENGPISWSYGQAKPTPNDHAWTKLSSMLWVEQPVGTGFSQGTPNITNEDQLAAQLVGFLQQFLEVFKELKGKNLYLTGESYAGTYVPYIASYIYAHPTALSLKLQGIWIADPSLSYDIIQEQVPAVDFVRKYENVFSFNQTFTAQIEAKAQKCGYTGYIQKYVTYPPKGQLPYPGNSSHISKDCDVWDDIFNAALIINPAFNVYRIFDTYPILWDVLGFPGSFEQVQVSPIYFDREDVKKAIHAPVSVNWTECSEGNVFTGRNGDTSVPSALSVLPGVIEKNNRTVIIHGTADFILLSDGTRIVIQNMTWGGQQGFQTPIKNDSFLVDGVGAMGTAHVERKLAYVEVVQSGHMVPQFSPKTAFQTMQYLLGFRANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKN1</accession>
    <name>A0A9P6EKN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_892134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKN1"/>
    <dbReference type="OrthoDB" id="3041043at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="40705" checksum="555F4E3DDDF44928" modified="2023-09-13" version="1">MDFPPLTADNSIMSSLSRKDLLILAQTPWDFRDRVDAYMRRASNIDNFLNKYFTPTEVAHFRYLQSRTQAIISGSMALQFFERVEYPNSDLDIYVENDHKKEIIAWLLQIGYLFESRRNKTLAEEMQSPPPPQDDTIADASGYFGRGVANVFNFFQDGPERRIQLITSYISPLRVIINFHSTCVMNIITHEKAYALYPKATFDDHLSVKHSTAGGNQDAARQKYADRGWTMVDNLSADKIEDSEFTHKPRHVGDRFCWQIDLVPKLELPESSIEINSWLFYGGHEDPSMVSWYTYTNGLDFKYIIGEREIDKFFRDFFGHSYDTYEGPRHQDARMLELVRAKRNSPQVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKU4</accession>
    <name>A0A9P6EKU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKU4"/>
    <dbReference type="OrthoDB" id="5592074at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7907" evidence="1">
        <location>
            <begin position="13"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="168" mass="19410" checksum="4F1A05F43400149D" modified="2023-09-13" version="1">MSTALETTQSPHKFFYLKATSSGKYANRYVRYTGSGHADVVLTEAHPVFLKFYLQDDKQLAAFKERVFGFVMGALVDVNDKDEGLRAVEMFEDKGDGGFYFDEEDAGKLKWKGVTDNDDVHWKGWVLKENPEDKYKGNPQLFWTTVEPDVEFKLENGMERVELIREYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL51</accession>
    <name>A0A9P6EL51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_833442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL51"/>
    <dbReference type="OrthoDB" id="3227921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="298" mass="32835" checksum="8535592B536D6869" modified="2023-09-13" version="1">MNSTARTLQYVIVTVNFTQIKYLDYYNDKVSSGPHFNTTTLTKGFNAVQVYIGIGNFDLQDMLSTSTGTTLIPGVNLIGVINLYRRRVFSSTKLSLWGIFDSYSQIMATEMAIYGLTLFVQWLSETLKTVEDYRDKSIFAGFATVGGLSAFLAGIFGAIFGTSIIKIVFAIKPLSVYGLAHWLQKPALREACVAEYPRIQQDTKTSPEDRGLVSFMNDHLLDMDLSDPSKESKSSSPDDIETLSNAIMTPAVPLELPGSRIFLDNGPKREEQEIALLEIGSDHRGGGSEYTTSSLSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMB9</accession>
    <name>A0A9P6EMB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMB9"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="89"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="415" mass="46219" checksum="A716AC7A5B42427F" modified="2023-09-13" version="1">MSSKPTVLIFGGLNTCSRALAAFLVPLEGDARVSHLRIVDKFSVHPPTTYIGPEFAKVLEKPEVDYRQVNLTITAAVASAFDPPEGLSTFDHVFDFTGEVRHDRSSMIQISTTFAVARLLGTEAAKRGVRSYVRIQQPFYETSGKHAAAEKDDIKPYETSGVWWHESLRMLASIQDLNLVVLRIGFVYGPYTNFGNIASLITVASVYGFLKRPMKSLWSPGKNPTNTVHVDDVAGAAWACAEWMASKGRAEANKLAGEVIYFHNDKSVMKDAEGVRAPDEKPVAPLFNLVDDSNSTLLSTGSTISSYFGTTFEFFNIVENAMFKWKDDLDDVNEQHVEGWTKMLTGSDPSITNSPLNPYMDKYTLEKHVLALDNAKVKNIINYQLLRPEFNHANIDELVDKWKQEGVWPNAARNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP26</accession>
    <name>A0A9P6EP26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dual-specificity kinase</fullName>
            <ecNumber evidence="2">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_759746</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="2"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP26"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14210">
        <property type="entry name" value="PKc_DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000087">
        <property type="entry name" value="Dual specificity tyrosine-phosphorylation-regulated kinase 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.30">
        <property type="entry name" value="DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042521">
        <property type="entry name" value="DYRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF22">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="440"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="241"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="740"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="782"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="740"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="798"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9532393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="830" mass="90334" checksum="02143A6CDD44B123" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP56</accession>
    <name>A0A9P6EP56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_674362</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP56"/>
    <dbReference type="OrthoDB" id="4243at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF0">
        <property type="entry name" value="HOLOCYTOCHROME C-TYPE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="233" mass="25463" checksum="769A13EB54108D3A" modified="2023-09-13" version="1">MSSASACPVDHSASSSSTSCPVDHSAPKSGSTSPSQGSEACPVDHTTRSNWSRFLSSEPSGSAHPTVPLSQDREMSSIPKKADGNWVYPSESQFFSAMARKNHNPQAADMKTIVPIHNAVNERAWGEILKWEAGKGGDACGGVKLVNFQGRPRDRTPKATMNILLGYSAPFDRHDWVVERCGTQVRYIIDFYTGKKAGPNGSDISFYLDVRPALDNWEGVKLRAEGLWKSWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQZ7</accession>
    <name>A0A9P6EQZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_867216</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQZ7"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="303" mass="33940" checksum="1700B0DE6D5ECDCC" modified="2023-09-13" version="1">MPFSKFKLNDGNEIPSIAFGSGSVNKGHDIHEYVEQAIEAGFSHLDTAQFYENEDSVGQAIRESGLDRNELYVTTKWSLGKVDDAIRSSLSALGLTYVDLYLVHGTWLLPDDNDMHLFWRNIERIKKAGLAKSIGVSNFNFEQLQSLVKIAHIKPAVHQIRLNPYNYQEMKPLLEYHAKHGIITEAYSSLAPITRYPGGPVDPVLEMIASKRKIATSQVIFLWVKAKGAVVVTTSSKKERLREYIAVGDLDDLTEEEVRSIDVAASKFEPPSGLDGKRMVVNKKLVLLLLLFSVLVSAFIFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER52</accession>
    <name>A0A9P6ER52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 88 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_935402</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER52"/>
    <dbReference type="OrthoDB" id="2317065at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040181616" evidence="3">
        <location>
            <begin position="20"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="399" mass="43791" checksum="CBDB5EB6651D55DF" modified="2023-09-13" version="1">MKLQIIALKISILVSHVLAAAPAQLFSPLVAQKVHNTFKLLPNPLQFPHTTDSTKGAWGLVDPNWWTSGFFPGTGYLMNTRKALCGDPTNELGTTDWLALSRSASNALLSLTDKNGIGHDVGFISFPFIEELTINPNNQTAINAVNRFAGLLAARFNSVVGCTRSWDTSDPTDFQVIIDNMMNLEVLFVSAALTRNKTLENIAIRHADTTQANHIRSDGSSWHVVEYNSTTGVAFKKRTAQGYSDSSTWTRGQAWGVYGFANMYRHTQKASYLDTARKMATYFINNTPSDGVIPWDFNAPLTPTPRPADTSAAMLAVNAFLMLAQYDPAAGAKDKWTNAALQLLGNNVPFAWKTSWQSLLSNGTSNKPSNNFNTGLVYGDYYFVLAGNELLKRNLTTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERB0</accession>
    <name>A0A9P6ERB0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_939663</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERB0"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF141">
        <property type="entry name" value="GH15225P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="39"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="255" mass="29476" checksum="288CC09D27879009" modified="2023-09-13" version="1">MNTETSGANGFPAKLPEAEEALVEKSFEQKGIITTVNKIPIQRADFRRLKPGKWLNDELINAYMQLIQTRADSASRPYDFGFRISPLRPTEFKHNILCLSSFVIQKLIALGYAEGKLRSWTKNHNIFSLDRLLFPINHSNVHWTAASINFVEKRIESYDSSDNTYHARFKILRQYLDAEHWDKRFQPFDFEGWTNYTHPNQPLQNNGCDCGVFTCVTLEALARGEDDLIFDQSNMPYFRKRMGFEILNGALKIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERB9</accession>
    <name>A0A9P6ERB9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERB9"/>
    <dbReference type="OrthoDB" id="5277092at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="96" mass="11216" checksum="DAC66D977A29FC70" modified="2023-09-13" version="1">MQLKMKQQKSQSQEIKDSLRAFIKEQHDPNTHYTFDSERGSGESEICREDAPSKDCLKLKLDSKKMFEAMQDEGFFCALPSDPERTYMHCKPLPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES56</accession>
    <name>A0A9P6ES56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Iron-sulfur clusters transporter ATM1, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Iron-sulfur clusters transporter atm1, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_844820</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES56"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140466">
        <property type="term" value="P:iron-sulfur cluster export from the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03253">
        <property type="entry name" value="ABCC_ATM1_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000004">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000186">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF402">
        <property type="entry name" value="IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="17">
        <location>
            <begin position="168"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="490"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9533950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="740" mass="82061" checksum="4EE8FE9752B61166" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES99</accession>
    <name>A0A9P6ES99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metallo-dependent phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_844774</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES99"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="83"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="484" mass="55006" checksum="2A4A95644E99E795" modified="2023-09-13" version="1">MVMTNATRRTAVLFAFIPILGLYLIYTFRLHYFIPAIATWPTQRQIVAEFSTYMRHRMFPWTKKQDALKQAMENGVRTPFRRHIVAVGDMHGDFGNARKVLQFAGVVDDMGDWTGDVDFFVQTGDIIDRGDDTIKLFTWMDQLRTQAHATGATVLNLMGNHEWMNAIGDWRYVYPSELKTFGTIAARQRMLSTGRIGTSWARNYTTAARLPLHPSIGPPNSPYPPQLSVHFQKESETDPREVLGPLGEVLEERSPDDHTESVGKAKAKRKINTPRRKGKIHYEDATHLRDPLSHSAISFVHGGLSPTFSNLAPFPSKINELAHSLLFKLQHRKQPRVSPPNPYPGLPLSSTYEEQELYDGNGPLWYRGWAMMDEETVCRDVDAVLRKTGTKRMVMGHTPDFHNIVSRCDGKIIIIDTGISHAYGGVLSALSIHYTLAPIGEDEDKKWLETEIVSALYADRREVIVQDEREIVGDFWSFEHEDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETE0</accession>
    <name>A0A9P6ETE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_340900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETE0"/>
    <dbReference type="OrthoDB" id="3030351at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="242" mass="27080" checksum="9C3E95FB115560E8" modified="2023-09-13" version="1">MPRATFENAKGPERIPYHLRTKPATPIEIPRRQRHVPSPLNSPTAYPSSPDLVFEMSPISATYSPLSTMFSVASMPPDHPEEDEPFMYRVPVFRSSGLEDRSWPRPTRSRESPMPSRNSSNGPISHTRRAESPHNDPVIITGDFGDGFDEGMSTHSTTKITGFFPLKPDQPPTADLLPKFVGRLSPPPRRSSFAPAPWASSGSGCTEEDMSYSQVDPSAFEFQRHLIRRIESKDRFASLRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETT4</accession>
    <name>A0A9P6ETT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein bS18m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_901743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETT4"/>
    <dbReference type="OrthoDB" id="21463at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="172" mass="19757" checksum="F7AA0E3926C971FE" modified="2023-09-13" version="1">MLARLSQTCRVASLARPFSSSSRSLFNLNDDLQSLVSEQVKVQERQAAAAPVSQPKPVEWDRFEYAKVLAPKHLTYKYRLKEQKRWKKRAIPTSREARPTDVFHQLNLDPRDFSTTSNLLYTFVTEMGKIQGRDATNLTARSQRLLGKTIRRAKHMGIMSNLSRPPNFGRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETY8</accession>
    <name>A0A9P6ETY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division control protein 14, SIN component-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETY8"/>
    <dbReference type="OrthoDB" id="5357220at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012535">
        <property type="entry name" value="Cell_div_Cdc14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34065:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08045">
        <property type="entry name" value="CDC14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="592" mass="64069" checksum="B7C3A2EF7BCAD243" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU26</accession>
    <name>A0A9P6EU26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU26"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="25439" checksum="CBCC01DA6461F6B5" modified="2023-09-13" version="1">MDGGRDEFAQPAVYSLISCNSPEHHDTALDLDCHAVEQLDCVLKEVSKLSDYSPKGRCQEQLKALHDYTPSEESHFELQHNFHLLEDIAEEVELNKEYWQEQQASHVYGVEDPEDELHFLQDIPLTAFDKRIQSIEERYWPARTPSNEVIPPDLSRNARRRRIRKQKKTQRSTGPNDVAVTIEQPSNSSRFLSSNDSQDDAKKPRRQRTRKKKTKNQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUD8</accession>
    <name>A0A9P6EUD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUD8"/>
    <dbReference type="OrthoDB" id="3258282at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="441" mass="49563" checksum="FFB70A1A656696A5" modified="2023-09-13" version="1">MAPSSPTSLDTHRVSPVRGQLEPYDPRTPAGSRYIQCTETPDELKVLLPPGTAAMYEQLLKLETYELSKKPTISWERLMDVRRLKDRMIRKCQKLTKTVIPTVKKSSRGDTFAFQTYVAPSDFRCKEMEKWFRDQQKRAGTLPRRTITTNGVIEEHTLTVTAPVRRPSTSSKQPIQRSITNPETSSRPKQRSTAPVQKPLPPIIHQPVRPAPFIPPTVSLPPAPAVPQTRMIMSPPPLPVLILAQREELGLEDDGVPPGYNSLDPTTFFEPPLPSEKIYPISSLADPNIPGAQPRPTLGRRPSCIKRNSSEIKSVTWADDDIDGQLSKYAVAAREAQESGKWEEVRALYKDQISGLENLQAQVKEGLEHLRSETDHLQRIDETIRKQREALDASFQSFEQKQNLFQEKVQEALTQATDVLAKHPQPLEAIKEASFSFSSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUG1</accession>
    <name>A0A9P6EUG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_20011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUG1"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251:SF1">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="G-patch" evidence="7">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9535566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="50863" checksum="CC7C580AE5198700" modified="2023-09-13" version="1">MSEKMIARWNAIPLDRPEESSSLKRRRNEDQQDSDDDISLISRSPSPRPGDAMDVDQKSLGKYDEYHHGSAREVITVETKLKSTNKGFELLSKFGWKEGQPVGLDPEGRTEPVPFYVKSDLTGLGKVSQDVEMIETTVSQRRGLDSERQQRETEEQRRAREDIVARKSALEAEISSTLRAFYCELCDKQFKNVAQYDEHTNSYAHHHKVRYRDMQANIRIKPQAEIDKRKEKERKREEKELRKIAAAQGIKMAKVPASSTTATVEPVQPTKSTLPVMDIDAAPAEPKKGWATILNPPESTTSSGSGFRNSGWATVGSSSLAPPPPSDPAPPPPPSEAPPAPPSNSMPSQTPSFRNAGWTTLDTASAPPKPSQAPNPSLPGGNSWSQVGASSNQPTSGSWSRSSFVSAQAPLCPPLPDSTARPALTSSTPGFAPVLIPQNPSTSASEPPPVRSNWQQFQKGAGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUR7</accession>
    <name>A0A9P6EUR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_781091</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="8"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUR7"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000034">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="9">
        <location>
            <begin position="17"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="10">
        <location>
            <begin position="231"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="521" mass="56200" checksum="1A791BFA0901DB5E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUR9</accession>
    <name>A0A9P6EUR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_779052</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUR9"/>
    <dbReference type="OrthoDB" id="274683at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000004">
        <property type="entry name" value="50S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_uL3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="327" mass="35393" checksum="2DF57C97F2213C4F" modified="2023-09-13" version="1">MFSLRVVCRHNSQNLTHLRLLSTTSTANANALTSNVGASSSKDRPEIPPSGDKWTPNSIRTGLIARKRGMIALWNDQGVRVPVTVLQLDNCQVTANVVTVRRDKSEYHAVQVAASDKPVKTTTKQMLGHFNKAGVPPKRIVKEFAVSADAHIPVGTELSAVHFVPGQFVDVIANSIGKGFQGGMKRWGFHGLAASHGVSVSHRSSGSTGQHQDPGRIFPGKKMAGRMGNERTTVQNLPVIRVDSELNLIFVKGAIPGVDDAHVLIRDAKKKMNCLSSHNQAKGLYEKVLPKGVDDLPFPAGTTELAKTLPPIIEAPSYRRSPFIPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUZ9</accession>
    <name>A0A9P6EUZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_841614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUZ9"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052527">
        <property type="entry name" value="Metal_cation-efflux_comp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43847">
        <property type="entry name" value="BLL3993 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43847:SF1">
        <property type="entry name" value="BLL3993 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="18015" checksum="C9F0C6F39992C983" modified="2023-09-13" version="1">MILKKCVFKGGNPQNMRISQLGALGAAIFFAGVILRAYTYRRLGRFFRFDISIQKDHELIKTGPYSYVRHPSYGGLLVSTTGWLIWTFSKGSWVRESGLMNTKFGKPLIAAYIVACILPPSLVTLSRMHKEDDALKEQFGDEWEAWAMDVPYSIIPGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHX1</accession>
    <name>A0A9P6JHX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_823363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157989">
        <property type="protein sequence ID" value="KAF9521792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHX1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF97">
        <property type="entry name" value="ISOAMYL ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040155972" evidence="3">
        <location>
            <begin position="24"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="134"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9521792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="586" mass="64797" checksum="88E23F1CC46ACF3D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHY9</accession>
    <name>A0A9P6JHY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158007">
        <property type="protein sequence ID" value="KAF9521645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHY9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="18703" checksum="6D651D2083E20B94" modified="2023-09-13" version="1">MMHQRPNMLGDETEYPLYTCPRLRYDRVVSIVEKVKWECINIDDSINDGCGNGVAAPKIIQQIHDNMPIPPIVLSRINDATSVRIRANNYLVTSISDSWYECSICVYGADVLRALKEYFVPGGFEDWTDVLGICDREVLVIQYDIMAFNYLEGLASHCQEVFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JII8</accession>
    <name>A0A9P6JII8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_864625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JII8"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="14663" checksum="BB0BB30A722B0DE3" modified="2023-09-13" version="1">MVRVSVLNDCLNNIVNAERRGKRQVLIRPSSKVVVKFLSVMQRHGYIGEFEIIDDHRSGKIVVQLNGRLNKTGVISPRFNIQHSQIESWVNLLLPARGFGIIILTTSSGILDHEEARRKNVGGKLLGYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIJ8</accession>
    <name>A0A9P6JIJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157947">
        <property type="protein sequence ID" value="KAF9522406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIJ8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="276" mass="31294" checksum="687CD94F623EB452" modified="2023-09-13" version="1">MYGVEKCEGSERVTSFERASPYPMRGVHKYRVGVASWFVLGLVLMELYLDKRKESHLIFDTPASAHAVPLALPQPAAHTVHLFARTGNTQLPTHDFFSIPEIVPTPTEHSVLLHPSSDVSKGIPEISEGNLPGITLQLRVNESLSGNEPVLEPEFYLGVHGIFRQRLINNLEAKAKVKEYRAKLKQTFQVFSILAELRMQSKLQMEETEQKRSEEKKKSSYAQAGVNLSVPKNHLVREIEATKPQPEFGSFVDEQFDQQRAEMEMVKAYVQTMEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIN2</accession>
    <name>A0A9P6JIN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_777307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIN2"/>
    <dbReference type="OrthoDB" id="3214502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="11"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="860"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="909" mass="103856" checksum="DC770B665E5B4010" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIT5</accession>
    <name>A0A9P6JIT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIT5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21271" checksum="0F0558ED32C0F11A" modified="2023-09-13" version="1">MNNELLRRGDLLFSTFWSSTSVNHPVSPYRTIPGELYSPLIIHPTTWGTFENLANSAETRKLDRFLWPLTLKAFSAFRNGGCIIYPSVASNPEQVSAFRFLDDNKVARCPTADDDGKLRCVADLDDEGVNFYEDTVSVDGDDEGCLDVYEDAVEEQEEALERATGTFRMESPGDKPHKLAPFDPIWLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIU4</accession>
    <name>A0A9P6JIU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Minichromosome loss protein Mcl1 middle region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_864133</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIU4"/>
    <dbReference type="OrthoDB" id="427368at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="7"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="9"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="134"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="405"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="710"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="825"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="870"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="870"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="885"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="929"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="971"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1011"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1044"/>
            <end position="1055"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9522661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1063" mass="117924" checksum="CDBC3D1678554921" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJF0</accession>
    <name>A0A9P6JJF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_60077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJF0"/>
    <dbReference type="OrthoDB" id="2676372at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="30250" checksum="F1BA5C842CE255E7" modified="2023-09-13" version="1">MLQVTTLDGVSDTPFLRSEVTIQSSTDVPTFLWDQQLQKPSTSAMPSWSSSHVPLMSDDSSQSVGFGALALEWPSTTPPAIPMLQSVSEKPHRAWHSRSFADTMEPSSGPKRSKSKGKKRVVGNAMQSYRHCNEKAPNMRRQSQNGVEHPTPSQTFDPLVCRLEAASGRTGRTSGVSNGTLCKQRFDHLDSFKRHLCNDHDIPKGHGNSTTPYICGWEGCEKTGTLSTYHRHLQSHAFRWHCPFPDCLKSYTRGDTFRNHIRDRHYGNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJG4</accession>
    <name>A0A9P6JJG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Aquaporin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_863238</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJG4"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9523232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="37097" checksum="4DB3B0DDF6E1C761" modified="2023-09-13" version="1">MSQTNQLSPVVSSHSTTSTHVHTSTHMGDHETYYQSSVTSKRFPSTIARLLKPRKAFNHIRHVLHQELAEFFGMTVFIFFGTAVNCQVVLSTNTGIASSPKGEFLSQTLGWGIGLAIGAWVSGGISGGHLNPAVTLAMATWRGFPWRRVPGYIFAQLWGGIVGAGLVYGTYHEAINIFEGGRGRRTSATASMFVTYALEYPSAATCFFTEFLGTAILVFTVMATTNKKLKVVAESVGLLPLALFLVLTGLSSAFGMQTSWAFNPARDFGPRVLLSFVGYGKQLYTYRNEYWIWCPIMAPFLGGQVAAAFYEVFVSGNWADDEQISPIHSKKATMSNAVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKT3</accession>
    <name>A0A9P6JKT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_877681</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKT3"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040512480" description="beta-galactosidase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="371"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9524253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1007" mass="111012" checksum="3FC97A11C72696F8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM41</accession>
    <name>A0A9P6JM41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM41"/>
    <dbReference type="OrthoDB" id="2142040at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="46473" checksum="CE1D51A9B243DB43" modified="2023-09-13" version="1">MGSKFTGDGAVDGKDDLYFLDFVQFRVQGTLFRVPTNGFTSSNPNFFKDIGVADQLLKNNVHEQVIELPEISRDMFKGLLLVMYPFTRTAETYDEWIGALHLAVLWGLSDVRTKAIAFISGTDDFKSKEPVEVIQLAKKLRVGSWLRDAYIRLVEGKDIDVGNLRPSSGSDPLDWETISLLFQAQSLFRKQPTGPAIDDAQCQCEGCLRQKRPHMKWGYEPVYRCTITGKTKKSVGTCVDQVFRQELTNIDPGLFSHSFAGERLALIQWKNLPDLNQRGPSVAPNEDIFLGSALLDSSVMPCFVTTGIDEYQEVFYFASYWADGEMPSEIFDVLPYSPERMEWVPTSQGKIPHGRQPISGGYDEEGRQLYHAGVPGSGLKLLGYTGEHLGKAMMTNFGAGVRTVEENYEILCWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN37</accession>
    <name>A0A9P6JN37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_450625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN37"/>
    <dbReference type="OrthoDB" id="3027122at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="83"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="730" mass="83100" checksum="B4DA022DD737541B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNJ6</accession>
    <name>A0A9P6JNJ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_744656</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavoredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNJ6"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798:SF5">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33798">
        <property type="entry name" value="FLAVOPROTEIN OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="5">
        <location>
            <begin position="54"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="27224" checksum="5A4D72814CF6BF24" modified="2023-09-13" version="1" fragment="single">KFKLVAPPNPGWTYGQKIDCTTAGKTWSDGENAGWKIMDTSKEDAITVYQTLIAGISPKPVAFVSSLSASGSANLAPFSWFNQVTHSPPVLSVSILHKLNGEKDTLRNIKETKDFTVNIISEPWVEQANSCAINAPIDVSEWDVSGLTKADSIYVKAPRVKESAFSMECELLQTVDITNPTTNTVTTTMVLGSMKAVHMRKDILNEHGVPDIGKLKPVARLGGTHYIRVSESYSLPNVKDSWDDEGEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNQ3</accession>
    <name>A0A9P6JNQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Neutral metalloproteinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_443183</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNQ3"/>
    <dbReference type="OrthoDB" id="2962374at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09597">
        <property type="entry name" value="M4_TLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052759">
        <property type="entry name" value="Metalloprotease_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032475">
        <property type="entry name" value="Protealysin_N_PP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579:SF1">
        <property type="entry name" value="NEUTRAL METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16485">
        <property type="entry name" value="PLN_propep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Protealysin N-terminal propeptide" evidence="10">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M4" evidence="8">
        <location>
            <begin position="160"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M4 C-terminal" evidence="9">
        <location>
            <begin position="246"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="47251" checksum="4B62E52D6A4B7D2A" modified="2023-09-13" version="1">MSAKAVKPNHAACCSVIPTYILSNIADSPHAPEAARTHARNALAHTLNFIQKHQNSITHQLSITQAHPGANQGQSFVPDHILNSIASSHPAGSEGEEAAQRSLRISSEIRDRREAESDSLRGAAPAKPAKRLNRVIYNANHTQILDESLARSEKGPATGDTAVDECFDGFGATFKFYADIFNRNSINNAGMSLIGTVHFDNAYNNAQWDGSQMIFGDGDGIYFNRFTASVDVIGHELTHGVTQYTANLVYQGESGALNESVSDVFGSMIKQFQHNQTSAQADWLIGEGLFTSKVKGVALRSMKAPGTAYDDPVIGKDEQFANYADVLKAELASDFDNGGVHIISGVPNRAFYLVASELGGNSWDRAGKIWWATLTDRRLTPSSNFQAFAKLTTEQAGNLYGESVKTAVENAWKEVGIDTGAKTSPVPKPHHPHAQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNQ9</accession>
    <name>A0A9P6JNQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNQ9"/>
    <dbReference type="OrthoDB" id="3224221at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="105" mass="12051" checksum="C671FFA4E5D577A9" modified="2023-09-13" version="1">MAHELRILRFKLYCARLDTILDRIPHPKDIDSEDEGLDNKTKVWLDAHKVVDALGIEGQSSDESERDGTATVYYAKQLEWRSTNVGCWLRKVDDYRSRLATGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP21</accession>
    <name>A0A9P6JP21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_425099</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP21"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="22196" checksum="E43CBEF5B424F630" modified="2023-09-13" version="1">MFQIESSLLGLVPFLSSVTFFKFQLKSRGKCTLNGRKLTVINDLIDKRSFLNSDRPAFEMIKLSNFDKLMVLSPYGDNLRKQRRMVAQEFAQSYVHNYSHLQEMQATLLVRKVVQDPEALRSETTLRIGISVLRSRIRLQCEVSKRRLTIRRSLVGGNVQQSERPRELSCQCFSCVEAPPKMATGFRVSSDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP71</accession>
    <name>A0A9P6JP71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP71"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="54" mass="5967" checksum="6D94677981349CEB" modified="2023-09-13" version="1">MSHTSWRPQGIPPSLGGSYMVFVVLSYISKMLRTVSPMGSDYCTSFPALSIIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPB5</accession>
    <name>A0A9P6JPB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-Aspartase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_869966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPB5"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01597">
        <property type="entry name" value="pCLME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF2">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="2">
        <location>
            <begin position="344"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="48137" checksum="86CB730385A6C748" modified="2023-09-13" version="1">MTAVSDSVIFRDIFSTPEASSIWSDRTRTHKLALVQGRRGIIPQNASAAIQAKCNVDLMDLEALGEETRKIGYPMLPVVKELVRMVNEDEPGLGEWAHWGATTQDVTDTATVLQLKETCRLVENSLNQIIEILQTLSVRYANTPMAARSNLQQAVPMTFGFKMARLLSAFKRHKQRLSEILPRLFVLQFSGAAGTLATLAETGLALEVHDELAEELHLKPADIAWHTERDRIAEIGAFFAILTGEVSEPYAPHRDSSSTMPQKRNPISCVYITAMAATIKQLSAALFDALVEDHERGTGPWEIEWIVLPQISTLTHATLVHTVLLLDGLEIHEDAMKKNLDLTKGTIVSEAVMMELGRFLGRQVAHDLVYDVCQKVARDGTEKKLLDYLLEDETIGECGVSRDRLQSICEPRNYVGLSKEYVWRVTKFDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ16</accession>
    <name>A0A9P6JQ16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_906518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ16"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="146" mass="17244" checksum="341A023DAF54479B" modified="2023-09-13" version="1">MLTRRPPVIGNLRRSDPKCPHYYVYGLAIRREDLELRGQELGFGSHNEFDRTSFALDDFYRRLNQFPEGNKELFRKCTITTIRLKKKPENRREGEPNFNIAYCVAIASNLNDDDFRFVDDEEAVKTIRELMGLQGAPGWYRHHHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQM3</accession>
    <name>A0A9P6JQM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_853586</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQM3"/>
    <dbReference type="OrthoDB" id="1850764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000502">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="9">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="84"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="142"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="410"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="57153" checksum="2D04EBE9E1436C2B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR46</accession>
    <name>A0A9P6JR46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate esterase family 9 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_812199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR46"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF5">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="427"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="964" mass="105893" checksum="5951D1922E483058" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRB0</accession>
    <name>A0A9P6JRB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_257252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRB0"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="9921" checksum="940BACC596157FCB" modified="2023-09-13" version="1">MDRIPPVPESIATHIRSLYFPVSQNSGPNLCRLCFGRALQPFPANIGQSKSEGPRKFFSSNNFPIDLEHYKGLRRVVGANLLPSPEEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRS6</accession>
    <name>A0A9P6JRS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_811363</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRS6"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="294"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="171"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="35999" checksum="7FFDFBA01152077D" modified="2023-09-13" version="1">MPAIRTPIATPFGLKASTPYDTAIYTPHSEKAPFVRIHTPGNDLGVQGLEGYEDSLSQWMNVGPLFAEVDYHETSSCPPSFAPSPQTDRSTYEEPLEGNLFTWPYEAGHNNFESTYSVVPEMPGFSSFSPSTSLGSFSPRSDHSGLSLSPQPSDFSTALNFDYSTSLPSEFPSTSNLSQSMPSLSHSPKSTLSHSPSPSCSSLEAVETIGKRSKSRDGSPTRTPENDARRRFPCLIIGCERRFTSQYTLKVHMEAHKPKPRISFPCTLGCNERFSRQHDRLRHEVAKHGKVCEFSCEDCGRFFSTKKTLGNHKCPVAQGGTRWVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRW2</accession>
    <name>A0A9P6JRW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_811202</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRW2"/>
    <dbReference type="OrthoDB" id="1792at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="522"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="845" mass="94289" checksum="B481E6E471400E6A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS60</accession>
    <name>A0A9P6JS60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_905483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS60"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="52584" checksum="4032E3131F24B880" modified="2023-09-13" version="1">MVLDYPRIFRLLESLPIELIAEIFRHAITAWSPNTIPNALAEIEHEFTALHLGAVCRSWRALVWHTPTLWSGVRVCATPKQIATQVVLLDEWLSRSGSLPLDITLCSPDNVDWLKAGDHSKLQSLIMTTNRYASRWRSLVLQIPGYSCGALPKPHVQLPFLERLRIDPMDNGPNDRFSLQGATALRRLDLNLRSVYLATIDIPLSNITHLNLDYCILAEFLFLLPHCPLLTDIVVENLRPDVGISVHSLFDIPELPLVLLSVQALTLRNPHSLEVNSLLASIVTPELKEFTYDGLLPPRDLTPFCAFLSRCPTLQEFSLFDRERSPRRIVQILEELKTIKTFKLDVSNRDENLPLNDQLLNMLHPSPGAQYLLPKLENFTFIGGLGFTWPRFIAAWKARINVKGFGEAEWTSWKFTIISNDKNPLADESFMEELKSLQCEADGRLKLSFRTPAEAKMQNVILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSR3</accession>
    <name>A0A9P6JSR3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="5">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_785100</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="17">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="5"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSR3"/>
    <dbReference type="OrthoDB" id="448573at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006659">
        <property type="term" value="P:phosphatidylserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000022">
        <property type="entry name" value="CDP-diacylglycerol--serine O-phosphatidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9532247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="243" mass="26491" checksum="BFA260FCC6E36228" modified="2023-09-13" version="1">MSQRKATNSNATKLNDDVSEKKESALHQYQETDGHFSLVRNFRLADLVTIMNGVCGSFSIFSSARFLVTNDPDYLWTALSLPLAGLMFDFLDGKVARWRKSSSLLGQELDSLADLISFGVAPAMLAFVVGLRTYLDTVILTGFICCGLARLARFNATVALVPKNEAGKSKYFEGLPIPSSLGLVAVLSYWASKGWVYGQEGIPWGTVTLWGKEGGRGEVHLVSFVFAAWAAAMVSKTLHVPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSW5</accession>
    <name>A0A9P6JSW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_892054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSW5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="11585" checksum="F30A7291DAC91A0F" modified="2023-09-13" version="1">MDRSAHDLWFYTTVANVLFIAGGFQGDTNLAVLEESQPFTFKKRDLTITATPPKDKTMSDLTVKDTVTITVESKHAADVRAHCRTGAMYQTHKTPETPVKHTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTF9</accession>
    <name>A0A9P6JTF9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTF9"/>
    <dbReference type="OrthoDB" id="545910at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="267"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="456" mass="51779" checksum="8BF11BF2AC0008CF" modified="2023-09-13" version="1" fragment="single">MEDTDTLLALVYSLIPSNQQESIKQHDALQALISSNGNVEDAVQLLLTKSCPGASRSVTKRKRGDLDSWLKLPSKKIQTETLDNPSKDEILDATSSKPLLSKPKSPNRSKLPVDLMAVLRQPPSPRKGPVQLPPMTLSTPEMVAKHTPCTLHYSILPPELACQLFYSMIDLSKGWKKNKWWLFDRVVESPHLTSFFARQTDGLDDDVAWQEAAQFWYNGRPTDPPSKFSPEMEEACQYIEKTVNEVTKTRPRFKKEWGGGFGDPHWRANVAASNCYQGGKESVGFHSDQLTYLGPYPTIASLSLGTRRTFTLREVVPNEQTTLRKAQTFNIPLPHNSLTIMHASCQERFKHSIPPQNAVDLFRPAFPRAEGEGIDPSNCRINITFRFYRPDFRPASIPRCRCNVPCILRPDMKNRDDEETDRYWWACYAGAQNDGMGCKFWKVMDMETEGRTTHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTP4</accession>
    <name>A0A9P6JTP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sodefrin-like factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTP4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040456490" description="Sodefrin-like factor" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12310" checksum="0CCB9A7CB354832F" modified="2023-09-13" version="1">MRFQIISILVAFPVLIQAVGPVCDFRLCTGTNGSGTCQTFTGGDTSNFCIALPSGVGGSLTWKSGKALQDNPVIQPSHISLYTGTACAGGESDFIDIHGFRNFPSGEVLKMAYCGSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTQ9</accession>
    <name>A0A9P6JTQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_471557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTQ9"/>
    <dbReference type="OrthoDB" id="549353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905762">
        <property type="term" value="F:CCR4-NOT complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10910">
        <property type="entry name" value="PIN_limkain_b1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024768">
        <property type="entry name" value="Marf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379">
        <property type="entry name" value="LIMKAIN B LKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379:SF3">
        <property type="entry name" value="MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="2"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="11832" checksum="0E6328243C037044" modified="2023-09-13" version="1">MNCPAPSNASGYAIVNNITTIARPFGNVKVFKAYLEIPEQLPLSKFITMRSELQSSGVSLIDCPHNGRKEVADKMLIVDMLAYAIDTPSPATVVIITGDRDFAYALSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUM2</accession>
    <name>A0A9P6JUM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUM2"/>
    <dbReference type="OrthoDB" id="3069822at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="674" mass="75429" checksum="B0C277756D4BC764" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW46</accession>
    <name>A0A9P6JW46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium activated cation channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_842775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW46"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF4">
        <property type="entry name" value="MEMBRANE CHANNEL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="3">
        <location>
            <begin position="252"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="627" mass="70509" checksum="2D667C7B799C1AE6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWI2</accession>
    <name>A0A9P6JWI2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_27585</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1058"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1086"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1113"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="13">
        <location>
            <begin position="400"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="618"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1206"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1250"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1219"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1252"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1284"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1328"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1381"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1406"/>
            <end position="1419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9535696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1419" mass="158433" checksum="5DC36A2587641FD0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWW3</accession>
    <name>A0A9P6JWW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_843478</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWW3"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001236">
        <property type="entry name" value="AGC/RSK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="342"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="627"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="232"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9535100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="704" mass="77027" checksum="A2B24E0332366A00" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX93</accession>
    <name>A0A9P6JX93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pescadillo homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Nucleolar protein 7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NOP7</name>
        <name evidence="7" type="ORF">CPB83DRAFT_802533</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pescadillo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX93"/>
    <dbReference type="OrthoDB" id="10264910at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17709">
        <property type="entry name" value="BRCT_pescadillo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="354"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="485"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="584"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="613" mass="69004" checksum="003FB6A4AF9B6FAE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC28</accession>
    <name>A0A9P6BC28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_932672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158147">
        <property type="protein sequence ID" value="KAF9521297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC28"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="172" mass="19794" checksum="556EC5282A2B1153" modified="2023-09-13" version="1">MGQSHHHFLDSCLMQHPTLRKSNAPIFSDHNVQLFQRSAIRETPKQDSYTPTNDTTTCSSEVPNFAESEYPNLQYQRSHHRIAVSLLDKFNDPKPKAHHRSKFPDIEWYWRAYPEMGGWQIRRGCAPRIVSTELGRSGSGWVVDKKRGEGGYCVESGFQEIKKEGCWSLVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BE10</accession>
    <name>A0A9P6BE10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158080">
        <property type="protein sequence ID" value="KAF9521401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BE10"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="376" mass="37727" checksum="85F37829D9537E25" modified="2023-09-13" version="1">MSQASRGGGNALSDDGLVATAGGGRRRSNRPTTVFTAPSGDNSCSGTPAASSAPLATSARVVYSGSQPGRVTTINPVCSDRPRDIGSPSTPQASASSVQQWRQGVNEEDTIRAGAARRAHSAQPSTPAPGGPGVCRGSGAVQPRQAIPLQLTGRADAGNSDAGVVAHALEEIAGWISLIAPSAADLPEQSSVADSALHLLNSLAYSPWALVQAPSSETISDRLATTAGGAWTAPPLTPSRQVTPSSDIEFDDEGPVEFPSLNPSVVQAMGELRVPGTDNRDDEVHMVNTTQTEGLAAHGALPTAAAARSGTSTAAVASGSAAVRSPAAPAPAVCPGLCDTLRQGGSADHCSRIPAAAKGKSRAPPPLNMATKPAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2U2</accession>
    <name>A0A9P6E2U2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_778886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158111">
        <property type="protein sequence ID" value="KAF9521350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2U2"/>
    <dbReference type="OrthoDB" id="5598737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305:SF1">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21673" checksum="6E369B67F616409C" modified="2023-09-13" version="1">MPQIRSRPQYPNLKHDQNPEASGKRGAKCSKHFREYGEKRLTGGIMVCWCSHSIAYGFHCIPKAEGRNDVFSAIYTRWQKAPEWIVYDFACAAAPYCMTREPEFFKDTRQGIDDCHSNGHTKCSPACFIKTYADLDPRLAKINTSAAECGNSGLGRIRKSVSYMKQDRAIIYIRTFLGVWNRHKINKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3E8</accession>
    <name>A0A9P6E3E8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157988">
        <property type="protein sequence ID" value="KAF9521796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3E8"/>
    <dbReference type="OrthoDB" id="3263746at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="581" mass="65461" checksum="FDA26096E3605862" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E507</accession>
    <name>A0A9P6E507_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_96733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E507"/>
    <dbReference type="OrthoDB" id="3071265at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="57095" checksum="F428A66C66DEB323" modified="2023-09-13" version="1">MEISSDSQCIPHSPPQMCELNADNDKTNHLELDALPRREAVSKINARHDPMAHHLPVELSAMIFWQCLPALPPPESFNRADDGLDSQLAQITHSLTSVNQNWRNIACSTPTLWNSIFLNVKEDVLCQENFDSLLTNIKLRLQRSGSLPLNIRFRDQIDDIEDLDDIDLSLRQAIVEELCREAHRWQNICFVGLEKVLENIPKYTSELTVGAPQLSCLILEKTDELNYHRHRWSPTIGNFNAPSPSPSYLSLKISLLDADIFNFHRLTISHFHSPITSSTFLYILVNSPCLTTFTTRIGPTAKDNRPSLAQFNFPFRHTSLHTFDLKIGRRDIDDPFPKITLPNLENLKLTTSSFRCSGFHEFLCRSSSRLKNFDLTSFWDEENFISTLHLMPALEVLHSDTEISPRFFQHLGRTADRAAGFLPCLQAIHFTTHKFPEENFSWSLIRTMIPVEPTINHRPLSKVTVELHPELRLSEEEEIILKDLWESDIVIEVIVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5L9</accession>
    <name>A0A9P6E5L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_915724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5L9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040270692" evidence="1">
        <location>
            <begin position="27"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="21788" checksum="1342C96DAB663507" modified="2023-09-13" version="1">MVLSSKFLRCFALTTLGLTQVVNTQAADPRPEVAEIISLAKDISKGWADIANSNVYKLITPDPEAIKALKDNISATANALNAVADTGADFRRKNETLTLDEATHINGIFDDSRKDILNSVWNIAISRQYLTGEGAGDPVGFADETLRIWNGTNWAQNVLMTISPSTWDLKYDEIYNYDTILPLWLVQSLFYDIQQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E896</accession>
    <name>A0A9P6E896_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E896"/>
    <dbReference type="OrthoDB" id="2552978at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="45389" checksum="8261EDB7CEA571FD" modified="2023-09-13" version="1">MTSRSRKRKYRPQGQGYSNYAHLGLVGDENELEFLGHHKRYAPAGTSSTLDTFNAEDSSNSFSESTDFLSLQGLYIQVYEADLVRGPSSESASAALEVVQYVPEDTGKGWKTTPTIGSALIKLGEDGFSIPIELGTVLNEEITPPSSSTPKEEITKLDIWVDRYDARLLLDAGAVAVSSSNSHLPPLTSIKPPDSPTGWSDLPSDAEDTFFLDNEEIEDVRREQRRLENERAREARLRARVEEDDEYVIRFGGKADVWGGSDEEPDEACKALLHRTATHLVSSPNPAQLEMRILANHGNDKRFAFLRGRWSRAWNLAKAKARMEMEKEKPNKKAVIGLLTGYGSGSESEDDEAKAKTLSLPQREDVSLPNQTIRSGKSKSPQVDEEALKEARRKRLKEWREKRQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8X8</accession>
    <name>A0A9P6E8X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_599750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8X8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8282" checksum="776D002973DEC5B5" modified="2023-09-13" version="1">MPMSQLSSFAVIFIPQSDSESESDRICAYMIQRREKIVAHCRRLNSSVAAPSTPSKEIFLKSVLFYLRSDITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E930</accession>
    <name>A0A9P6E930_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E930"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040341837" evidence="2">
        <location>
            <begin position="18"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="365" mass="37510" checksum="592975470152F498" modified="2023-09-13" version="1">MRSSTFSFLLAAPLALAATIDVSVGPNGNFVYQPESVIAQAGDTINFTFNPKNHTVTQSSFDTPCSGLDGGFKTGFIPVGTGSTDSRQFTVPASTGPLWFYCGQVGHCAAGMVFAINAPAEGDPKSFSAFKARAQSSGGVASGASSPPATITTPPAPHWVSATATVTWQSSTYTTTYTSYDGTPPPTPAAQPMDHKITVGDNGKFVYSPANISASIGDTVTFEFKPKNHTVTQSSFLTPCTKLKDASGNPGFASGFKPVGASDTTFPTFQIKINDTAPIWGYCGQPGHCQAGMVFSINAVESGPNNFAAFQQLAINSGSTNTTSTGSGSPGSPSGSPSGNSALTARIGYGFTTLFILAASCALIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E961</accession>
    <name>A0A9P6E961_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_885823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E961"/>
    <dbReference type="OrthoDB" id="3051800at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="649" mass="73122" checksum="9A5C53C2673846EB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9I7</accession>
    <name>A0A9P6E9I7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_838416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9I7"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="2">
        <location>
            <begin position="116"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29613" checksum="03F0179C6CF3E0A0" modified="2023-09-13" version="1">MADSISPTQKIIFYDILCKRPLETTSPFTPVTHWSLKYKGLPFERKLIELADVMPLGEKLGFPKTMWPTGAVNTFPVIEDPNTGAKVSDSFDIAEYLDKTYADAARPLLVPQGTRTLQKAFLAAIWADQMPLFRFIVPLLHPKTTAYSSDYYVTSREAMFGDKLENLLPSGQEEVVEWAKVKRMFDNYETWFDEKEHKPYITGDAPVLADFYFAARLYLIRAALGPDSKQWADISSWNGGRWAAYLNNMLKEYPIEPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9N6</accession>
    <name>A0A9P6E9N6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PPPDE putative peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_860170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9N6"/>
    <dbReference type="OrthoDB" id="21221at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="7">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="171"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="6">
        <location>
            <begin position="328"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9525052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="655" mass="71288" checksum="367B2DFE3271F343" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA66</accession>
    <name>A0A9P6EA66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_818912</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA66"/>
    <dbReference type="OrthoDB" id="5952536at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="61"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="271"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="9">
        <location>
            <begin position="536"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="685" mass="77824" checksum="89D605301B2D8811" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAG0</accession>
    <name>A0A9P6EAG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_548704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAG0"/>
    <dbReference type="OrthoDB" id="3271131at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="38600" checksum="7F015AE56AA38988" modified="2023-09-13" version="1">MISERHKPKDYDWAFDLRANFADSDDSEGEDDRKTGTANSGLSRDDALLKEIDISSRSDSVNFKPNPFSIAKINAIYRSARAKEPGNQRSPQPPTIQTLNNNQQKSQTKITDRFKVKASKAALPTLSPARPLHSKHSPLEGNSCQLHELVPSSPSSHVIIPGQERCNFDSQDFSAANKHPPKNPGVPLNSIPANISRDSSSNFVRTSSPPQKHAHILAQKRLPGPTIEPQLKENNIVESNRGNFRHSTRFPRIPNRPSFSSPLRPPGWKSLQNGLHKTSSPGPSGCLPRRFLPLAQLTRPSLPNYCDDDRDLPVRSPNLTNRMPNQAEPNTIRSKPIILVFEFMTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAT7</accession>
    <name>A0A9P6EAT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAT7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="96" mass="10530" checksum="29395B29CF1500B8" modified="2023-09-13" version="1" fragment="single">MADISVHPPQGQAIPQEIQPLTTYDSKGTRLTCLTLADGDSPEPIVPSGKRKRDEDVNSEAGEDDDEDAWGGIEKQEESSDEVEDENEGELEEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB21</accession>
    <name>A0A9P6EB21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB21"/>
    <dbReference type="OrthoDB" id="2142040at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45625" checksum="BE8E4ED5CCC14EE5" modified="2023-09-13" version="1">MDGNSLSMGSKFTGDGAVDEKDEMYYFLDFVQFRVSPRHSISRTSQWLHLLQFRFFKEIGVSDTLFKNDRQERVIDLPDISRDMFKGLLLVMYPFTRTAQTYDEWLGALHLETMWDLPDVRSTLQLTTNTRSLERILLGASSSHTTAKKHKLGSWLRDGYIQLIQGKDINIDDLRSSSNSDPLDWETISRLVQAQSLFKRRPTEPVIIQEEFEACSRQKGSHLKWGYNPAYCCSIHNSAEVCVNRVFQEELIKVVSKLPLQSFAGERLALNTEDPFPRTNELGPRISLESHLGRVTTQPIFLASILQNSSVIPCYATDLFCPYTWFPGNYTENSHEGRFDLLPYSPEQMEWILTSHGNIPPGRQPISGGYDEEGRELYHALAALPPDEGLKVPGQTGEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBP4</accession>
    <name>A0A9P6EBP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_498518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBP4"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058504">
        <property type="entry name" value="DUF8191"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047126">
        <property type="entry name" value="RNF141-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12109">
        <property type="entry name" value="RING FINGER PROTEIN 141-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26609">
        <property type="entry name" value="DUF8191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="209"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="317"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="130"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9526095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="578" mass="65191" checksum="7D1FF8222FC46AF1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC34</accession>
    <name>A0A9P6EC34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 20">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="14">IMP dehydrogenase</shortName>
            <shortName evidence="14">IMPD</shortName>
            <shortName evidence="14">IMPDH</shortName>
            <ecNumber evidence="14 20">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">CPB83DRAFT_858599</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14 20">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14 20">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homotetramer. Seems to be able to form heterotetramers composed from more than 1 of the 3 IMPDH gene products (IMD2-4).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14 19">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="14 20"/>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC34"/>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000007">
        <property type="entry name" value="Chromosome 19 SCAF14664, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 18" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 20" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="5 14 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 14 17" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14 20" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="22">
        <location>
            <begin position="125"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="22">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="14 15">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14 16">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14 16">
        <location>
            <begin position="331"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14 17">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14 17">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14 17">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="371"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="394"/>
            <end position="395"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="418"/>
            <end position="422"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00062187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAF9526059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="546" mass="57967" checksum="35B61EDF7EB40411" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECB9</accession>
    <name>A0A9P6ECB9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECB9"/>
    <dbReference type="OrthoDB" id="2863512at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040107888" evidence="1">
        <location>
            <begin position="20"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16420" checksum="AC01A60FB397B381" modified="2023-09-13" version="1">MRFFTSATAVFAFVCATTATPVPGKVKSVSDVTKRGNGDEIVYLVTCNGEPHASRAVYYAHWHDSQTYRAHAPDAISYGNGNLGLGGYSSPGSTQYIFLNTKLDVTLNNLNPGWYQVAGSAINQFGTSFICRMDNGHQLYSDCFSNYYCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECD0</accession>
    <name>A0A9P6ECD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_876860</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECD0"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="33588" checksum="ECA0E861A7289E40" modified="2023-09-13" version="1">MESSDGNSFAPFAQLIADEKSWIKGALIGPGSLGKVYLGMNASHGLLMAVKQVELEPAADHGSPHEHIQDEEQGSEKRLSSTKVLALEREIMERLTSFEHQNLVQYLYTSREEDSGSQFLNIFMEYIAGGSVSALLRDYGAFEEPLAKNFTSQILQGLKYLHEMGLIHRNIKSSNILVGNSGGVKISDFGMSEFKKVDDQHSVFWMAPEVVKQSANITAKADIWSVGCLVVEMLAGKRPWAELTPLQAIFQIGSGVIPTMPSDSPAQVTDFLQQTLRIDQETRPEVNTLLLEAWINKDTSEATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDH7</accession>
    <name>A0A9P6EDH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDH7"/>
    <dbReference type="OrthoDB" id="3172239at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="40558" checksum="55AE0A77B9F31EB6" modified="2023-09-13" version="1">MSGARQTRRRAKFEEKWDLNLRNPGSQLPPEDLLLIFGFVRLGQEEDKQKLVELVNTQEYILSDSDDEFTENSSWVVVGQVCHRWREAALRSSELWSHIEFEDQKCRRAVEMLKRSKEVLLNIQLGLYFMDKRCKDKHTKMVVSRFALSQVQKIWPVAKNSLFGLETVTIPNSALFSKEMRCRTSKRSSLTTNYQELTAESLRILKLSYVALDLNAKFLRGLKTLQLYFCPILTPFLQLLDCLASMPSLKELDLQLFAFPLDRSELPLVKGHSLNSHPMELTHSTLFSSKSPLKTTALLLAVVKNPIDLDIRVLNMVKITQTTWKVSGILLQRISQNLAVHSECILLGCRAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDJ0</accession>
    <name>A0A9P6EDJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_769650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDJ0"/>
    <dbReference type="OrthoDB" id="3269759at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="15779" checksum="5FD48EEAD3ADFBA8" modified="2023-09-13" version="1" fragment="single">MAFKDNFLKVPKLLPNGSNWILVRDQFRWSADACGLLRHIVEVVVEPTPPSVTSGSGMTPASGSASGAATTVEAAVQEDQKALRGFDILHDRWCQNEVTIKQAIANAVPDSVFNRIKAKRTAKEVWDALVAIYEERSLMVAIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDY0</accession>
    <name>A0A9P6EDY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_856322</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDY0"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040221">
        <property type="entry name" value="CDCA7/CDA7L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169">
        <property type="entry name" value="OS05G0300700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31169:SF8">
        <property type="entry name" value="ZINC-FINGER DOMAIN OF MONOAMINE-OXIDASE A REPRESSOR R1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Zinc-finger" evidence="11">
        <location>
            <begin position="67"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="146"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="602"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="655" mass="73216" checksum="5866A7CF2C78357F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE78</accession>
    <name>A0A9P6EE78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase pc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_768529</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE78"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="516"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9527452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="593" mass="68103" checksum="0EDC48B4EAD41C9A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEX9</accession>
    <name>A0A9P6EEX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="4">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_869858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEX9"/>
    <dbReference type="OrthoDB" id="2425929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="324" mass="34203" checksum="BCC3ABB275DE332B" modified="2023-09-13" version="1">MRSQAFTLAKDITRIVAAGASFSQVDRLNGSSSTHILSNTLSVFAVAGAFAAAGQLQQVSNYGTNPTGVQMWVYRPSGLVANPALIVAMHYCGGTAQAYFSGTQYANLADQLKNFMVIYPSAPNVAGSTCWDVHSTGTLTHNGGGDSIGIVSQVKYAITNYGVNASRVYMTGTSSGAMMTNVLAGAYPDVFVAGAAFAGVPYGCFAGASAWNNACANGQTTKTAQEWGNLVRSGYPGYNGTYPKLQIWQGTADTTLNYHNFAEGVKQWTNVFGYPATGAAQQNSPVNGWTRTTYGPNFQAISAQGVDHNIPVQTNDVLTWFGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFQ2</accession>
    <name>A0A9P6EFQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_359913</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFQ2"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="652"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="726"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="815"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="657"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="736"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="769"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="815"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="880" mass="97765" checksum="D2740FEE9DF80E71" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH06</accession>
    <name>A0A9P6EH06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_835395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH06"/>
    <dbReference type="OrthoDB" id="2963117at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="26270" checksum="7CE5C4EC57B55876" modified="2023-09-13" version="1">MLDLDDPGLLPNFLEIEDQPSAQDIKAMIDDWVPWNLMYATLHEPQYENSLYGPWNTLLSAIFPHRRQFVIKPQALLRRVVEEDLSDQDISIGSYEGRHESRTLPGHEDERLLPDFAPCKFQQVWADEDRSLIAERTYKLLCILELKRNAAFAGHARSQIITYVRRSQYHPNRQEPIFGYLVLGKTIQKFGMLGPLVAGPMGDAVDLNSREGRVYIDELCQLSADNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIP0</accession>
    <name>A0A9P6EIP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
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                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIP0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="137" mass="15425" checksum="24C98210083E256F" modified="2023-09-13" version="1">MNLRIRSAQTFPNRLPGQLVQSCGLGFCLLPLGWIVGVGMSYSDGVVELEFGRRLLPDRLDRPPHVFYSTATDRGKRFKTSFYLGYPLEFFMWTVISHRTCTEHSILDPQTLPSILGLFHKKSSLPSGRPKSIGSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIS2</accession>
    <name>A0A9P6EIS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852492</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIS2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8395" checksum="EACF77E3179ADD18" modified="2023-09-13" version="1">MSPKDNSISSSTAHGSFYITKRTSEVLRTEQNPAEARAANIRNAELPNLIVSKKCSQTFAFTRTLILVCLKYWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIU1</accession>
    <name>A0A9P6EIU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DHS-like NAD/FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_182904</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIU1"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="357" mass="39789" checksum="41FBE5ABEA868CC1" modified="2023-09-13" version="1">MRISVPGLPRAILDAQPVIAVKNIDEAVERVTNFLQGGNVGLITGAGVSVDSGLRAYRGKDGRYMNPNYKPIFYHELVDSSEKGKAFRRRYWLRSFLGYPHVRSTLPNTTHFAFAALQHTSYIPWIITQNVDGLHHKALELGAPSSWNLSRISDRILELHGSIHSVQCSRGHVIARNKFQDWLTRSNPSWHRFANDIARRSQKLRTNPDGDVDIEQLGVSYEDFVVPDCPTCLLAGHRNSVQKPGFVFFGESIPEAVKERALRCVEDCDRLLLAGTTLATYSAFRLLKHALEQRKPVMLLNVGPTRADGLSGIEKIDVATGTILPTIARAVIGRPAEEDLIIREMIQSGIVKPPPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ78</accession>
    <name>A0A9P6EJ78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Copper radical oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_850134</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ78"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF105">
        <property type="entry name" value="COPPER RADICAL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040191932" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="50"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="156"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="281"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="391"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1015" mass="106719" checksum="272BBB4F5726F542" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJD3</accession>
    <name>A0A9P6EJD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate-binding module family 13 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_159678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJD3"/>
    <dbReference type="OrthoDB" id="2131701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23422">
        <property type="entry name" value="beta-trefoil_Ricin_MPL_CNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="39"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="16033" checksum="E6EBAEBB2DBB6600" modified="2023-09-13" version="1">MSITNGGRFYIHNKKAGTVIDLDTRDNRSVQCWSKWGGANQQWEFLQVEGGWQIRNVAQRTYLTFDGNAQDGQRLIGSQNPFTWNIWPSDHDQRAYMICVPNTKQLIDLSDHGNIRDGTAVQLWTTFKSDNQLWTVENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK12</accession>
    <name>A0A9P6EK12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GPI biosynthesis protein family Pig-F-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_849490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK12"/>
    <dbReference type="OrthoDB" id="17366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009580">
        <property type="entry name" value="GPI_biosynthesis_protein_Pig-F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06699">
        <property type="entry name" value="PIG-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="33816" checksum="696B741BB69FC4E2" modified="2023-09-13" version="1">MANKKKPMPTKAPNTTSGTSTTKAGTVGSKPSIPIASYISIAGVHSTLWAFAVLFLPRTSFLSPLTTPEWDPTQLTSRDKPQHPFLEPLTLNPTATLLWICFGAAVLQTWWASWLRKWWLDIGLRGSDAEKRVERQQYDGQIFAMFRDAWLATLATTLPIHFILVLFGASFVTHVTKTYLLALLLSIMVVYPPALVIGIPTLSNNSGAMFRRWTWVRLFAEFWPRNLVERALVYPATGAVLGTWVGAFPIALDWDRPWQAWPLTPTFGAVAGFILASIASVTVSSIHQVLQEHAESQGNAQAKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK37</accession>
    <name>A0A9P6EK37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK37"/>
    <dbReference type="OrthoDB" id="3068811at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="442" mass="47830" checksum="DD99C5E72C3057AD" modified="2023-09-13" version="1">MEVRRKLEDAKALLSALGPRGEALVSHLDAQDAMSEPQAGESPTPADPVPMGSFGQTSFWGCSSPAEPCPVPAANDEVPPADMSWGGPGNTPTIDEPPVDLWGRGIPKKKKGKRKEAFGLWGASSCHEPSPQVERLSTHPTDELFFGGHSKASSSPPLLSAFPSPPTSPAPSVYSRSSTPELKNINLAFATPQGSQILFQNLQTLSATGSTEMISDLVNVIHSTSMKSISITFFTPEVQTIHPSAVVRLAICKWFGSISQVTIEAENSSFPPSRSTLPKAVFKKLLLAPLIRCLDLKGWKIEELDASLAALSRLESSKLEHLSLPFHSEAPGISLTRLGFIADSCPSLLSLKCRLKHLSNVPTTSEWSSSNTRNYNFSNLTVGNVDAHPKIDRALDIARYIDRLFPAINTLKTPDGPGQNAEQWELIGKIVKMLQEVRLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK55</accession>
    <name>A0A9P6EK55_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_834241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK55"/>
    <dbReference type="OrthoDB" id="3056787at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF5">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="46125" checksum="621B3BB3F02C0869" modified="2023-09-13" version="1">MALLDPLTRELEFLALSNIVHQEYHERETSISSGLQLRGCCCQLNILRVLIAVLSVTATTLIAFNFNLAAGNQSNRQTNVPIDAVQILQKCYALNTPADPPNNFSSRSQTRRPAGNSLGDLLLDKGLIKTFGNIEEVVLKSYNNLRVIEVHGAWVMPGIIDVHSHIDVNDFNSDNDLILPWPRSLDGLNTHDASYRLVLSGGVTTVNVLAGSGDAIGGQAFTIKLRPTVKRSSSFMVLEPPHGLNGSQVNTSLPPRRRQMNTRMDTQWALREGDWDDLGTLPEDLSGKLSLMCCTAQSRFTTIAIRLSTSTTWSDVSTQVAALRNIFIGRGVEDELANRVTKVLQGDLVLAVRVHSADITANIAQAQERRRKQTRDEDSAHSSLKVPFGLQLTWTATDPEKHYFPSGCTWRNCWPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKH5</accession>
    <name>A0A9P6EKH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exo-beta-1,3-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_105245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKH5"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040248206" evidence="1">
        <location>
            <begin position="24"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="422"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="783" mass="83210" checksum="F2A551B50C641552" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKU8</accession>
    <name>A0A9P6EKU8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_751306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKU8"/>
    <dbReference type="OrthoDB" id="3060861at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="53" mass="5858" checksum="E3F95F9D09616C81" modified="2023-09-13" version="1" fragment="single">ETSCYLFVGAQHSAANKPPIHYASPRLRKEGGSVTNDLATQFLQVIKQLIDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELH2</accession>
    <name>A0A9P6ELH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="14">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_761360</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="14">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="14"/>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELH2"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001522">
        <property type="entry name" value="FADS-1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00476">
        <property type="entry name" value="FATTY_ACID_DESATUR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="16">
        <location>
            <begin position="318"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9531300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="47455" checksum="C4BEB5E2A2D56922" modified="2023-09-13" version="1">MPSFTRTLKAPPKTTGIRWFNVAVLTLTPLIALNGCFTIQVRHETAFFSAIYYVFTMLGITAGYHRLWSHRSYNATLPLQLFLLAGGTSAVQGSCYWWARAHRSHHRHTDTDLDPYNSNRGLLWTHIGWMVFKSELRSGPSDVSDLRQDALIQWQHRHYFLLLVIFGILVPCIIPGVMFDDWWGGFYFAAALRLTIAHHSTFCINSIAHWLGDSPYDDALSPRDHFLSSLLTMGEGYHNFHHQFPMDYRNAFLWYQYDPTKWFIATCKILGLAHNLRVFPTNEIEKGKLAMKLKELKQVQDTLIWPTGPNELPVVSWEIFQRESKARTLILVAGFIHDVSSFLDRHPGGRHNLVSNSGKEMTAAFFGGMYAHSNAAHNAILLSMMRVGVLEGGVEIVGQRPTKPPVLRKLYIAQAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMA7</accession>
    <name>A0A9P6EMA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_761502</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMA7"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="47"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="39972" checksum="2CA6502E28372685" modified="2023-09-13" version="1">MATFSKTSFNASVYSLSRPTYPAKLFDYIFSYHSQGSPGVTRWDRAVDLGCGTGQATMQLRRFREVVGVDPSPGMLEKARANLAVGDHSRSPTATFKFVEGSAEDLKLNVEDESVDLVVAAQACHWFDWSKVWPETRRVLRRGGTAAFWVYTEFRLTKHPALIPLITEYAQGSDPSTSVGPHFQRPGRTILERYLVDVPEPSTVLKDATLSDIDRVFFGADEGTTLPTNSRIEPILLRREMRWRDLLGYFQTWSALHTYHEKFPDDLKREEDTRFLEQDLASVSRLASSLLLFYFYLFIHEDDIRGGDISHRFWKDLRQRAAERSSNAKVGVNDKVEVEWPVALLLVRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMC5</accession>
    <name>A0A9P6EMC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMC5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="7754" checksum="FE4AB0C85FC9E542" modified="2023-09-13" version="1">MYNLARRYIFVICKSTLSGNLDIYFRLFSFSTSTVINFVVHVYFIRCCISPASIRIYSCHSVTWTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMH0</accession>
    <name>A0A9P6EMH0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMH0"/>
    <dbReference type="OrthoDB" id="3244737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="31586" checksum="69CFDF627C2C495E" modified="2023-09-13" version="1">MEPRSLENIYTELYLELLKSLATEDPGLEDLLTDISLGNLLNSADGTIVLRQEDLTAYGTPTRRHLDSSTSQKLLTEVNNTLEIISTLFHGENHRAKDNSLNKSLPDSIECFTAEIISMEEQRAAHKDIVEALVQQINEAQGQYDGAVKTAILEVLPKYNQARAASIDLIAATIEASLQRLNLIRGQSQRAFYNHHANAIPGESKSVSQAIARAYEALKEEEKYLAAEAQTLDHQLQEYDTLLQLVDSGTSGYKQIIEDWAKTKRETDECRKDLRRLGWTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMK5</accession>
    <name>A0A9P6EMK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_833357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMK5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="787" mass="88559" checksum="6E2096251DC8D052" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EML8</accession>
    <name>A0A9P6EML8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_79663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EML8"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF15">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="605"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="518"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="851"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="899" mass="100431" checksum="DC9B0374D1C6E2D8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN59</accession>
    <name>A0A9P6EN59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L22e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_848276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN59"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="121" mass="13630" checksum="7DADDA7CA7600B6E" modified="2023-09-13" version="1">MPKAAATKGAATKHKFVVDYSKPAADGVFDGADFEKFLHDRIKVEGKAGHLGESVKVVRDGNTKITVTSNIPFSKRYLKYLTKKFLKKNSLRDWIRVVASSKDNYQLRFYNITAGDDDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN83</accession>
    <name>A0A9P6EN83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_914117</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN83"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000252">
        <property type="entry name" value="Related to calmodulin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF26">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="5">
        <location>
            <begin position="212"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="477"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="592"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="637"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="688"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="704" mass="77146" checksum="D4C425F758DA8FE6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENM2</accession>
    <name>A0A9P6ENM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_759601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENM2"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="322"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="440" mass="49932" checksum="7308C12F8CE97989" modified="2023-09-13" version="1">MSISLLSNTYLDENSARVKSKPVPWEGYQRAELITADELSLIKKVDRQPKSKTDSVLLSEGKAYALLYLTLLKNLQRVDTMQSILVLIGDALLDHDERIPLFFNAAESDPELPYVPLLKALEAQDEFVQLKAAQILTVLLTAQRGQLRARQLQTFLNVLASFMQGQSTNKRDIAVQCLESLLSRPDCRQEVWRIPGITAGFVEILNRHPGPQMSYQVAFCIWLLSFEQNIAEEINKKYDIVPSLMDVAQTAVKEKVIRVVVATFRNLITKAPSANLPAMLVCQLLPFSKNLAARKWSDEDILEDVQYLKEELNTRFQSLRPVTTYDEYASELASGHLSWTPVHESDDFWKENATKLNERDYEQLKLLIKVLKESTDITALAVACHDIGQYVKHYDRGKKTVADLGGKAKVMELMTHPNSDVRYRALLSVQQLVSQPWRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENP6</accession>
    <name>A0A9P6ENP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytidyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENP6"/>
    <dbReference type="OrthoDB" id="330671at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="2">
        <location>
            <begin position="89"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="29625" checksum="B7E2E6C86FA42F9E" modified="2023-09-13" version="1">MDNILLEVNVLLKGLNEDLEPNLGDGIDVCYRISGDAIAVPLPGSISSLPQSYIPVSGPYDLAPTTITPSSSPSPSSSNMPPSFPNTALGGTFDHLHAGHKILLSMAAWITHSKLIVGLTSDVLLVSKSYASVLESFSTRSARVSSFVEFFKPGLTIDIQAINDVYGPTGWDPDIQALVVSKETLNGGEKIRARRKEKNLPALKTFLIDVVSATSASLEHEDVEWLKENKLSSTEVRRWIVAKEKGKQGAEEVEKERSEVGKELIEVLKNEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENR9</accession>
    <name>A0A9P6ENR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_665682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENR9"/>
    <dbReference type="OrthoDB" id="6423603at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="1">
        <location>
            <begin position="64"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="26477" checksum="00EBE0D7973FAFD5" modified="2023-09-13" version="1">MTSENLLTILKPFKPSSLPSEEVLVGSGTSLINSSASWTAGRTYHDGRVKTCQRPKGPGDGAPWYCRHSEHMKEEITFNELWTKLSVNKAVNEKNYIHEIKDSIKVKQVSPTAEIWAMHYHFTPPVTDRVFTVFQVVHLSSEEGKPRVGTIVSLPVDLTSPEDQGLHDLEPKGAITGRYVSVERVMELENGNIEWRVVTSSSPGGNIPSFIVNSSMAKTIAHDVPSFLKWYRTLSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPU7</accession>
    <name>A0A9P6EPU7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_580832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPU7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040430288" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9404" checksum="098273F0B6C48F2D" modified="2023-09-13" version="1">MVCPLMALINAWLVLVFLSKKAERICLVECYKNDIRRRHHLSATFHYPSSTHSQQPRKVLQAICCATSFLHQLIRLPVGTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ86</accession>
    <name>A0A9P6EQ86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SNF5-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ86"/>
    <dbReference type="OrthoDB" id="10258327at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="457"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="53985" checksum="D3915A09B3EEB55D" modified="2023-09-13" version="1">MTNAPLPKNAAQPMRATKPRPSRTTTLPSTPNPYQQPRPPQIHYPLAAPLVQVPLITKQEPSNPPLPPLPTQPQAYTTSYDSRLNTGVSLLVQPNLASAAATSLRTSRRTVNYADPGSGDEFPDAGAIDSEDDDFLASGGVRTSIRQSRSKTAASLGAFKSAAGVSTPRQNTGTPQPEKSSLEKSYLGLFPPPQFIKSTYRLQATPEFTPAYLLEAQAQRRTSLVPIRVEFETDHHRIRDCFVWNINETLIKPETFATTFCNDLGISSHEWASTIATQIRAQLEDHESVAAMELGLDGALAVDEPPPNGEEVPECRVIVSLDVQIANHHLMDHIEWDLLSPLTPEEFSIKLCAELGLAGEAIPLVAHAIHEELMKHKKDVIEWGVVGGEKVAESVEDPNAPRDKSGHGLMKDKTGLGLGLGRAPRDGRGPKTLRSVWRDWAEAEEFRTTFEELTAEDLEKREIERERATRRLRRETSKFQSSTRTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQY3</accession>
    <name>A0A9P6EQY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_543269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQY3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="50" mass="5885" checksum="B0F5499B184272B3" modified="2023-09-13" version="1">MSSYYLSSSFPSISKHFELYNLFGVRQNCFLWLIYYVLSFIVSMAFLGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES16</accession>
    <name>A0A9P6ES16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES16"/>
    <dbReference type="OrthoDB" id="2877409at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="51332" checksum="BD39A0AA3A7750F2" modified="2023-09-13" version="1">MASSFQNLPPELIDSVFHYLSKKEILACSLVCNYLLPQSRRHFFHTLYIISLSSSPRFSFHPNVEKRCGPDGIADFQDLLKTEPSILTYIQHLHVEVNWDWLFFFRLQNIEHTELLEVLQTLCPLVDQFTLKLKYQVPDSMRYHLKNVHDALWKPFVLQNVTMLVLEGIESLPFDIARCSNLAGLTLRQCTFNVDDVVSNSNTPETSMMLTDLTSLDIFLDEKNLDRSLCCAESVLQFSARSIERLKLIVHPGVSSYHHEERANHRLESSGAGQSGVSSRTIQKVAEGITGSKFLSLASLPSLRHLVFEIVDDMSHQEDYVFHPIAQFLRACAPNTKLSSISLFTTLHVDHSQLPQVDALLSKDLKRRDWQTLDGPLYDLGEMLQRPISVKVHAQVKVKRDSVWGVPKKKIPVLQETLIFDSLFRNHFLALFKSEFLSLTYDWTIDMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESN3</accession>
    <name>A0A9P6ESN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_843738</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESN3"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040120807" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="21"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="223"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="562"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="563"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="581"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="583"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9534132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="604" mass="65673" checksum="02EB87004094CE90" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESR1</accession>
    <name>A0A9P6ESR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rho GDP-dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_781437</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESR1"/>
    <dbReference type="OrthoDB" id="1683373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.30:FF:000001">
        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="22169" checksum="84827C07DAAE50D6" modified="2023-09-13" version="1">MSAPHDEPDDFAPSNTPGYKPTAAKTAEEYAKLDAEDESLARWKASLGIIPGAADAPATGPKVSILTLELGSPTLPAGKTITFNINDQAALAEIKKNPIVIKEGVEYNVRITFKVNHSIISGVRYIQIVKRAGVKVDKMEQMLGSYGPHPKGEAYVKNFDPEESPSGMLARSGTYNVRSRVIDDDGEVYADWDWSFKLAKEWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET96</accession>
    <name>A0A9P6ET96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit D</fullName>
            <shortName evidence="5">eIF3d</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_878961</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET96"/>
    <dbReference type="OrthoDB" id="16538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098808">
        <property type="term" value="F:mRNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002191">
        <property type="term" value="P:cap-dependent translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03003">
        <property type="entry name" value="eIF3d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007783">
        <property type="entry name" value="eIF3d"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05091">
        <property type="entry name" value="eIF-3_zeta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016281">
        <property type="entry name" value="EIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA gate" evidence="5">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="303"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="615" mass="67545" checksum="DE5F88DA6E1E2FF0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETM0</accession>
    <name>A0A9P6ETM0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_842583</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETM0"/>
    <dbReference type="OrthoDB" id="272778at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF21">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="35748" checksum="83E849BE3044641C" modified="2023-09-13" version="1">MSFENAAITKGLMITLALTSIFAGLFDIKHYFHLQLTPHLSRHHQYWRLITHLLAFPNSSDLFLSELILYNVGVHVERQFGSIKYASFTFVSLLVATLLELSTLLLFHRAGLNQFAFGPTALVFSILYQYSRIVPPVYTYRVFNVPLNNKSMNYLLAFQLAISRPLSSIAVACIGVMTGQIYRSDIAGLNTYRLPSMLVNWAQSFVGPFIGSLRPPRRTNRAYPEDIAAIAARLANAIGQNQEVITTARTPRTAAPSPLTTGSNETPPAPSVMREWVDELTGRADRANAGLRVPTESEISNLTSMFPSMDRQVIVGALQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETU6</accession>
    <name>A0A9P6ETU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_831235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETU6"/>
    <dbReference type="OrthoDB" id="3245306at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="798"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="845"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="884"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="925"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="947" mass="102846" checksum="7D090AD1E7D4D438" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU57</accession>
    <name>A0A9P6EU57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU57"/>
    <dbReference type="OrthoDB" id="3335429at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="251" mass="28414" checksum="38C5D15DECFC4D3B" modified="2023-09-13" version="1">MRIGDMFTCCDETSGSQLEPVLELQEKSGELAALLQLLHHPPSPPLELPRDNKFDPVVYDPASIIPLPLLKPLLSTLADKYSLEEEIVDVLKVHLLAHAPAHSLEVYGFASLHGMEWEVSGASQYVLPMASYRFEEVKVIPTVAAYHNLVRLQDFRVKALRDLLLGEELFPHGYGKCQSHWEMSNEKWDRQRKALIGRIESATDVAGEMDALTDTFQDCKMCHKACTAAVEMLAYKCRRLPRRLDQLPNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV00</accession>
    <name>A0A9P6EV00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TFIID and SAGA subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_841666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV00"/>
    <dbReference type="OrthoDB" id="10266330at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="9">
        <location>
            <begin position="133"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="513"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="561"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="603"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="645"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="687"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="723"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="727"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="789" mass="85257" checksum="7477146C65937A51" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVA1</accession>
    <name>A0A9P6EVA1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-type serine protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_841646</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVA1"/>
    <dbReference type="OrthoDB" id="2146116at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="269"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="33"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9535374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="479" mass="53112" checksum="73A2E8DD6D446FC2" modified="2023-09-13" version="1">MTAQDPPSYTNPYEPHDEPFDISMAKHACYGCDDEKGRDLKNPHAYEDDEVFDTVYGGDDRSRYPSDSTYHDEDRPTPAKRHSYTDDDQRTGQYAPVDAVDSAPLVREMPAKKGWSTSRNMEYADPEGQEARDRAKAGPLGRFFNSARYPLQQRIEDKKRGIGRQKHPFVVYILTVAMIAVFIYELVYNSQQQGSPISLKPVINPMLGPSSSALISLGARFPPCMKLVQQVPPSTNLACANNTANPVTEICTVADLCAFGGIPPSGEPNQWFRFITPIFLHAGIIHILLNMLSQVVLSGQIEREMGSGGFLLTYFSAGIFGNVLGGNFSLVGVPSVGASGAIFGTLAVTWVDLFAHWKYHYRPVRKLIFMTIELLIGFAIGYIPYLDNFAHIGGFVMGLLVGTFFYPVISETKRHRTIMWVFRLVVLPLAIILFVVLVRNFYTSDPYAACSGCRYLSCFPSAANNRCQGTGITMTSSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHQ8</accession>
    <name>A0A9P6JHQ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158007">
        <property type="protein sequence ID" value="KAF9521642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHQ8"/>
    <dbReference type="OrthoDB" id="3061143at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="727" mass="79347" checksum="A647CF2DCF991575" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ65</accession>
    <name>A0A9P6JJ65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_915335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ65"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="17688" checksum="D9E075B1B84C9DAA" modified="2023-09-13" version="1">MIAGDWEVDEDMKGVSKDRRKPRHNGRQEETGHDGKVCAGITKSVRLLAAITTRLTFVEPPRPPHLLREPLPPYQRHSFALSAILANALETAISFNLTKSSLSMRCIGGTRLLLRGGIECRGIRCPALDWVARKTQTDNRCDLGTGRSLWRRGVGNVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJJ0</accession>
    <name>A0A9P6JJJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_910767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJJ0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="30260" checksum="A51039C256C6BCBB" modified="2023-09-13" version="1">MQPSIARLLNPDLAAEERNAILKMGRDFVAACIDYRHRYPQTGPEEVRRFVVGLNEFVEFLHPRLNRDTISSSWPPQSSSSSEIGHGQVTPPQADDHQCTQSTIRTGLKFRIPARKRKRVELEDDWEPEDFRPKRVMSEPIITSSVPLHEVSPKLQPTPLDRSYAFYETYYGDRPDSRKRRKLSRTSSNPHVTLTRSDTELLDAAEVLTSMKTQPSPSGSNSPMLPPAPPRRAKSKGRKGNHQTRLASSIPSVRRSARLQSDLLKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJK2</accession>
    <name>A0A9P6JJK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_691765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJK2"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="288"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="453"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="716"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="652"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="674"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="760" mass="84186" checksum="E2802D0CEA652735" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKF6</accession>
    <name>A0A9P6JKF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_839100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKF6"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="626"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="920" mass="102600" checksum="0AD4F9B178DB39B6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKH1</accession>
    <name>A0A9P6JKH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_774820</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKH1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="556"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="701"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="780" mass="88077" checksum="418F6E5D7164C90D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKY3</accession>
    <name>A0A9P6JKY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acid phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKY3"/>
    <dbReference type="OrthoDB" id="2865258at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="409" mass="47038" checksum="AE741FD2BC871BC0" modified="2023-09-13" version="1">MSFPKLVALDTDGTIWEGKLDETVWGKGNGAVHALEDVIERVDSSLLRDKTNNENTLRIYDDVSAIISDILKNGASLAFVSNNSANLKAVYDKALSLFVATNPADDKEFPILELAKYNEVSEEPKVEQFRKIRESSGLDYLEMILFDDEAVNNLVRIQLGVSFSAIRDKKGLSWDAYQEGLTAWRRMSKATIPSNPSTKPTPVIIGYSGQSRETIDFVQKGEGWTRPWTCRWGFGLYVTDHPGIAKFYSDWEKAEGREGWVCAVWVRDYEKWMNMVDKVWIPENYTGLPQMDNRRTTPEETGWNQEDRDLAVDKKWGIQTPYVLFSRHRYMDGMPIKLNTRSNEMLITTQTMRSLVYVTEISDEEAMRTPIPYDYHLHTKQWNIAIPEETKEDFLKHGETEIVDFIMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL00</accession>
    <name>A0A9P6JL00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL00"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="97"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="749" mass="84845" checksum="753C4244C959558C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL29</accession>
    <name>A0A9P6JL29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL29"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="7384" checksum="8EEA7F8618FA3AA5" modified="2023-09-13" version="1">MFPHLLKNSLLRWKTCFVLLFRILRRKGTWWHKRESHPRLLPNWCNITHNMTFVAPSEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLA3</accession>
    <name>A0A9P6JLA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_946557</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLA3"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="425"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="727" mass="80984" checksum="D9FC1B4742CC30B8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM12</accession>
    <name>A0A9P6JM12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM12"/>
    <dbReference type="OrthoDB" id="5964929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="871"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="803"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="877"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1151" mass="120097" checksum="7D75A547A2A39388" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMP4</accession>
    <name>A0A9P6JMP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Uricase</fullName>
            <ecNumber evidence="5 8">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_876878</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 8">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 8">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 8">Belongs to the uricase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="5 8"/>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMP4"/>
    <dbReference type="OrthoDB" id="9992118at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004846">
        <property type="term" value="F:urate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019842">
        <property type="entry name" value="Uricase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00366">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 5 8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>5-hydroxyisourate</name>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="35617" checksum="39759D71D0109BFB" modified="2023-09-13" version="1">MSGTLTAARYGKTLVRVLRVVRDGSWHNIVEYNVDVLLEGDIATSYTDADNSVVVATDSIKNITYYLAKISPHILSAERFALHLGTFFVSKYSHISKAFITIEQLRWSRIHVSEEKSPKGHAHSFFRNGDDKRLAKVEVDGSAGKDKLIGKVTAGVKDLLVLKSTGSAFEKFYRDEFTTLVEVNDRIFSTSIDLTYTFAPISIKPPSDERKLDFILPVHKGENGYAGSVWDLEVPARALAATLDIFATDESASVQATLFKMAQRVIAENALVDHVSYSLPNKHYVPVDMRYIGTDNLTPEKAEVFTPLAAPSGLITATVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMZ2</accession>
    <name>A0A9P6JMZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_748517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMZ2"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="141" mass="15866" checksum="39E8DDBD3587C2DE" modified="2023-09-13" version="1" fragment="single">VVVKFRQTYGEVGRKLLSSKSLAPRFRFCRHVELVRMLVVVMDFIEGIPLVANSLKLDIDPGTFKIQSLRDGLKELHNQVLVHGELSASKIVLGESGVMLLDFEYCGPERTARYPVDVDTGREMGRQEGSRRGGLIKKIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMZ4</accession>
    <name>A0A9P6JMZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMZ4"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="24649" checksum="2740B36CA2006AE3" modified="2023-09-13" version="1">MDQMGLILKLWQLLNQVKSLEILPGGLDDWISADVAPTAQKSSRTFPFMLVEGNLGIPKQIIYALYLSAIARPLRFGPKVLDTQEVYNVISASAVVLILNSGHQTALHARKRLIQSSQLENAQNNPLSETIAVGASNSREVYLVSSLDLPKFPRHLLISHPHILRINHSILNGPLQRKQHYFRKSFRKTFGTNGTSSCILAELIHAIIMPGIIGGGLRMLSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNA4</accession>
    <name>A0A9P6JNA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNA4"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="879" mass="96782" checksum="22E547EB76792E13" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNG9</accession>
    <name>A0A9P6JNG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_856459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNG9"/>
    <dbReference type="OrthoDB" id="18412at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="206" mass="22751" checksum="8A8FE98983D73163" modified="2023-09-13" version="1">MAPKNKELISCQICEEQPHKYTCPQCLVVYCSLTCYKKHKESSCSTAASSIISPASTQSTTEKSQKELQAADEEMFDNSTLLRPLTSLNWPYVPEESTFPDPLKRDDPKTLQISQYEAIATSPAIRKILSDDKKLPELLTSVDKLRGAEREYALQRALGVDNQIDVGGNGPKELSEDVLAFRKLAEAIEEAVRGGKEGALGLNWGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNV2</accession>
    <name>A0A9P6JNV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ima1 N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_377271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNV2"/>
    <dbReference type="OrthoDB" id="5966927at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034506">
        <property type="term" value="C:chromosome, centromeric core domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034992">
        <property type="term" value="C:microtubule organizing center attachment site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071765">
        <property type="term" value="P:nuclear inner membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042321">
        <property type="entry name" value="Ima1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018617">
        <property type="entry name" value="Ima1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538:SF1">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09779">
        <property type="entry name" value="Ima1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Ima1 N-terminal" evidence="8">
        <location>
            <begin position="11"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="352"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="407"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="590" mass="65764" checksum="745CD7ABD5113494" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPI0</accession>
    <name>A0A9P6JPI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_361109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPI0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="17296" checksum="F604A9067EC00940" modified="2023-09-13" version="1">MKRIVSSSVETLLVVYETKLQNFTSFTLHRRSSDDDWTLGSLVPMYRRCHQHLERCSSRQSKLGLGRRRPVWLTIEMILATVMSWQLKCDPIQGLIWLLNQSLALERQVPATQGRLKGVDMIYQNRGSYLDLLYGCPNVHSDSCSLSVPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPR1</accession>
    <name>A0A9P6JPR1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPR1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="446" mass="50477" checksum="7635D8B1D91929EB" modified="2023-09-13" version="1" fragment="single">MNTGTSWSQRSFIERRIMLLPTELHDQIIDELGFTESENVGSASVDRRRTLAACLLVSHSFRNRSMRYLFNVVRLKGHQSHVLRRATLLNAILARESTLDKSSLLPTSHFIQEIVISPIGVDSRVNETGNSLATLLSTIRTRMEEGFGPKNLGLDFRRQNWSNIVPPFKEELLALIQSPYLNFLSIKRLVLVPPSFLHGLQIIGLSLQDVRFVTTETISVPLNLGNIHPPRLTRFECDGYIPGFVHTTFLDLICNKLFADLKILRWEAAEFDEKTNLKQILHSTANSLEELDIGIFSWQLNNTEGLGSMTKLQQLHLETECLATTVSNIANFFNIQVPLSRLHTIHFTFRKAHNTSSSREGQLPPGLIEQRNDCQLLDNHLSSLHYSNLKKVLVTVKLDWPAHWQNSSSVEEVRSSATAELRALFPRLAASPLTNTSFLPNVEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPW0</accession>
    <name>A0A9P6JPW0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_855137</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPW0"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="154"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="556"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="597"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="770" mass="87019" checksum="F8CB742E22FA71D4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQL7</accession>
    <name>A0A9P6JQL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_853892</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQL7"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000120">
        <property type="entry name" value="MAP kinase phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF530">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0271350-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="219"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="617"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="683"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="767"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="774"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="798"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="922" mass="99487" checksum="DD0F2FCF8E93F2DC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQQ4</accession>
    <name>A0A9P6JQQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_882575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQQ4"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="530" mass="60033" checksum="6E2A6526CEA5BF10" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQT1</accession>
    <name>A0A9P6JQT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_257125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQT1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="14900" checksum="FFF261F9B11FDD85" modified="2023-09-13" version="1">MPYRRLFLTPLFPTRPLSLVHIIIHIPVSLVVSYLNSNAVTEALTKTGTYQARNKWTAWVKQVLPVLFFTCCFAFIRRDVRVALTHHAHRFCDLASPPAISYLLRARRVCASPKPEARLFSSSQEIMVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR57</accession>
    <name>A0A9P6JR57_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_852880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR57"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039773">
        <property type="entry name" value="BAG_chaperone_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329:SF16">
        <property type="entry name" value="BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329">
        <property type="entry name" value="BCL2-ASSOCIATED ATHANOGENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="BAG" evidence="3">
        <location>
            <begin position="89"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19064" checksum="5765A954106C197E" modified="2023-09-13" version="1">MAVTVMWGDQSFHFDLPSPDTTLAAVKHSIAAYTQLPYNAFLLIHDGAVMEDDNAPIDAYHLRPNSTIAIVTRDNAAHLTTTNNDEAAQIAKIQSELASVQNTLVPAHAQFMHTQSLHSSPKEKSRLSELLLQALIRMDAIVPEKDWVDARAQRKAAVRTIQELLDQLDSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRC3</accession>
    <name>A0A9P6JRC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRC3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="292" mass="32501" checksum="A7D791282EE802C4" modified="2023-09-13" version="1">MASSWRSQLTEFYLHKQLWISPIYPCADVYAALAQMPNLELFSVECAVLDFSNDTPHLSNSICLPKLRRLELNGEAFECFNVILTLHIPPTCALLIQISAKDIGLPDGTFPLLAQQPSEFLHSFFPPIHTLTLKIGISQFSVVTEARTNLFFSSSAQQVGMTIQGGWKTLQYGDIFESVRLVEFAAQLTSLNFDIVQRAVPEALAAHPAGQEILDQFLKGLVHLTNLTCSNFSVDYLIRIRLPILPKLRSLTIKGAATRLWSVSSAAIVFKRWRSGQGLPPVEITEIVDSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRQ9</accession>
    <name>A0A9P6JRQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_851055</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRQ9"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000007">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="122"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9530148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="37809" checksum="77FDC5A4054AB401" modified="2023-09-13" version="1">MADTATEIDLDSVIDRLLEVRGNRPGKPVQLAEYEIKYLCTKAREIFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLQSMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDITGWSENDRGVSFTFGPDVVSRFLQKHDMDLICRAHQVVEDGYEFFAKRHLVTLFSAPNYCGEFDNAGAMMSVDETLLCSFQILKPAEKKAKYPYGGMNMGRPVTPPRKPKKKDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRS8</accession>
    <name>A0A9P6JRS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_833762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRS8"/>
    <dbReference type="OrthoDB" id="539810at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="496" mass="56091" checksum="55D384E37E57D835" modified="2023-09-13" version="1">MANDVSTRTTVHLEAKQHIRHIETPHAYRLTAQAALTNQLSPLSDPYNTSFRQLTMGFSLIFIRDQPITERRLKKLETEWASSPIDVLQTRLDFLSLKFKVSGNNSDALADLEACIRVGRKEFQETARSIMRSIAGREDLVLRIGHRDHHTLRATQDEIIDILSEVEPKGKVERILIPVVQMRRKLLGDANTDTLRSMSRLADQHLKHQEWAEAKSLLLAILDSKTSSGHMMKLAKVHAEQGHWDKAERLLARVLEGMKGDIEVDRRDRLYAMEELAKAYRGQRLWAEAEYQFRQVVAERTSQNDEDVETWVSMDSLGKLLVDLGNKKEGKRWLKAASERKERLRVDCSKTVKMIESQAQTLDSSDTTSFAKMPVGENIILDSPAQRAIGVVKDNTPEREEGKSHMSNTTKSQIAQARLGKHATKKERIVADVNHFRVEEAQQHVQRGEAFIGGAVHMNGQSAFNGASNVTVNGNLTITFQTVAPQPRFSARQHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSM2</accession>
    <name>A0A9P6JSM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSM2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="23177" checksum="A8A71D53C3288465" modified="2023-09-13" version="1">MSVLQRNLQIFSERSSKIDPPIDCQGHSGPFNKRRFELGSNMNHKAQYFLPRVYAKLALVWLPFATTSDDLDVDFATLTMEFYEKIFFSYAIIARTGVRRRLADVFLQNPTLYKISVTSLADAYLTRKITVVTLISIKICQQLACEGAGYYCPTLKRPTPFLLPLSWMFATLHSDLVPWPNGIWVLVTEWSMQGRLTVADNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTB9</accession>
    <name>A0A9P6JTB9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_890940</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units, alpha, beta and gamma.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G protein gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTB9"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031681">
        <property type="term" value="F:G-protein beta-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.260.10:FF:000003">
        <property type="entry name" value="G-protein complex gamma subunit Ste18/GpgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.10">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015898">
        <property type="entry name" value="G-protein_gamma-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036284">
        <property type="entry name" value="GGL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041848">
        <property type="entry name" value="Ste18_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00631">
        <property type="entry name" value="G-gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01224">
        <property type="entry name" value="G_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48670">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50058">
        <property type="entry name" value="G_PROTEIN_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="G protein gamma" evidence="11">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="9237" checksum="4366C7138BCA965B" modified="2023-09-13" version="1">MNSRPHKQSMSELKLRRLTEHNQRLREDLSRPRARVSEASASLIRYCKTTKDHLIPSVWGPVTKGEDPYAPQATGCNCTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTG3</accession>
    <name>A0A9P6JTG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTG3"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="28045" checksum="CD0904CDF4BC0809" modified="2023-09-13" version="1">MTITLYDIPSTVPGSSWSPNTWKTRFCLNYKGLQHKTEWVEWQDLESTLVKIGIPPSRKDHRSKPRYTIPAIFDSTTGVYLSESFEIAQYLDRTYPDTPKIFPDNTAGLQRGFHQALTPLVEPIKALILPVEATRLSSASQESFQQKMKDYLSLELGEEDKIEMWAELRENFGVVNGWYSLGNNPGPFILGEAPSWVDFVLGATFLWSKLIFGENSSEWKEIETWHEGRWKTLLKQLSMYQVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU31</accession>
    <name>A0A9P6JU31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 13 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_782320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU31"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11318">
        <property type="entry name" value="AmyAc_bac_fung_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006968">
        <property type="entry name" value="PRK09441.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006969">
        <property type="entry name" value="PRK09441.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="7">
        <location>
            <begin position="31"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="522" mass="60251" checksum="B221989F772FBF9A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU98</accession>
    <name>A0A9P6JU98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_832385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU98"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="18071" checksum="5F7ED7D4685D8947" modified="2023-09-13" version="1">MDYALLPFHGHGFIAICGVGQTRRERLSLIIRSRFAINIHHSSLDGLVDTNTAELMALVMESAESSKFVNVDEMGTNPDTELRPHTVTVKREGHLNWERLAGMEEVQGGTESSSPKDQVDEPGPPLVPVILHHGEGDESLDDGESSVTKFVDHKENFREARAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUR0</accession>
    <name>A0A9P6JUR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUR0"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040535394" description="Hydrophobin" evidence="6">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="10894" checksum="CF902A0DDBAC472B" modified="2023-09-13" version="1">MFSKLAVVFVASIAAFVAAAPGGINNSCNTGPVQCCNSLYKSDSSEVNVIKQLIGIDIPVDALVGANCSPLSIIGVGGGSSCQSQPVCCSNNSFKGLVAVGCSPINVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUR4</accession>
    <name>A0A9P6JUR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_878953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUR4"/>
    <dbReference type="OrthoDB" id="37297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="11"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="22922" checksum="8EEC8D003E17D6BE" modified="2023-09-13" version="1">MSLQPSLRPLIILGNRNAPHTLDVFLDYVCPFSKKMAGKLDSIVKPLISNGGKYDGKIKVIFRLQTQPWHAMSTITHEAGLAALHASSEHFWPYSLALFEHQDEYFDIPTQDLTIRQVRENLAKLAATVLPSNTIEKFKDLLALKSTPNGGNAVTDDLKYNIKFSRQNGIHVSPSVLLDGLFQSQVSSGWEEKEWSEFLGKAITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUW5</accession>
    <name>A0A9P6JUW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUW5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="13307" checksum="EF40D3ED237D3877" modified="2023-09-13" version="1">MPLDVVERSTMVSYFLCTMMRKSPRCFDCSGFIFICIFISASAYSSSSLVSSAFVIYFAGGHTDHISAYQRGTMCTLDFFVRALLGTSPTSPHLFKSYSSILLKLKLDICYHHTIFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUZ9</accession>
    <name>A0A9P6JUZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_879157</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUZ9"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="79"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="24194" checksum="B3C89EA1879F4B0B" modified="2023-09-13" version="1">MPGKSVLFVLTSADKTFTGRPTGWYLPEAAHPYYSIFPHANIDFAAPNGPNPPIDKHSVENFKDEESVKFLNDETVKQKLATAKKLTEVNSKDYEAIFYVGGHGPVIDLAIDPANAQLASDFWNDGKIVSAVCHGPGALVGAKDSSGKSIFYGRKFTGFSNAEEEASGFTKDVPFLLESKIQELGGIFDKAPGLFEGKVVIDGKLFTGQNPASAKPLGDAIARALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVS5</accession>
    <name>A0A9P6JVS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_842332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVS5"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000001">
        <property type="entry name" value="Iron-binding protein IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="5">
        <location>
            <begin position="99"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00071673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="21844" checksum="034A6DB76F461B68" modified="2023-09-13" version="1">MSLALAHNLQSSMLRTSCRSSSVATRRAMMAPALRTYHPNLRPTLPDQPPVAIPADKVASTSATPLSADAASPQTAAPPPPAPKAERPRPKIRATKAALSLTPTAVDRLNALLKGPTPQLIRIGVKNKGCAGLSYHLDYVDKPAKFDEVVSQDGVRVLIDSKALFSIIGSEMDWKEDALSSKFVFKNPNIKDACGCGESFNVKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWM2</accession>
    <name>A0A9P6JWM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">mRNA biogenesis factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWM2"/>
    <dbReference type="OrthoDB" id="205569at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12622">
        <property type="entry name" value="NpwBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="456" mass="49816" checksum="5C2E2D860354466C" modified="2023-09-13" version="1">MGKNLNPADSYRKAQRKKELKKNKTGRAKARDLAIVKKDTTDLEEAISELESSRADAEKLGELKAELEKINKKKAEYVEEHPEARRLVYRRRKQGEPEPDLPTKKPRNYFGKNGLPRHPERSIYYDPVMNPFGVAPPGMPYAERPLLPGEVDSEAESEDEDIPLPSGLPPGTEKVTSHDDIPMPEGPPPPRHLQDKMPNPLPHFPPPPPLSPMQPTMAHPFMPPAGHFMGSFPPPGFAPSTMPLPPPPFPPPFGGPFLPSWSGAPPPPPGFPIMPNGPLPPTAFPPPPKFFQRQQNDSSIQDPLASIPHQTFQAHQASQRFLANPSSPSTQAKVPLLANPSLPAKPVAAAQMAAATVSAAPELRDLKREATEFIPSAVKRKKVAAPEAKLNAAPSVTPSAEDEKIEDATQVRPDLVNALKNQFGPVPPKILPQLKPEAKTDYDKFLDDMGDILGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX38</accession>
    <name>A0A9P6JX38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_912226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX38"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="6">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="21576" checksum="18AEED9E3A3596F2" modified="2023-09-13" version="1">MPLSQERFLAISCLNVGVGPGGTTNLLARIAIVNYVGETVFDKFVSPTTTVTDYRTTTTGITEENLYSPEAWSFNDIQQYVASTFKGKILVGHSLWLDLSVLGLPHPAVDTRDVALYVPFRNALRSPNQIIGLQTLSWQLMQRRCQEGQIHPVENARAALDLYRSDNLEWENAIVGKKWPCALPPSTFSRCYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX84</accession>
    <name>A0A9P6JX84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nuclease Le1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_779961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX84"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040431999" evidence="8">
        <location>
            <begin position="21"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="317" mass="33850" checksum="8F9FBB912E5DCCF3" modified="2023-09-13" version="1">MKCTTCILGLVALSIPGVYGWGATGHQTVGQVAMSFLGPKALAFVKSSLGSTYNQSLSVAATWADDVRSQTAYKWSSPLHYVDAEDNPPTTCDVSFSRDCADGMCILSAIANYTQRVVTTSLGAQQQQEALKFLTHFIGDIGQPLHVEAIATGGNDISVTCAGKTSNLHSTWDTGLITQYLSVNFQGSMTSWASSLVSRIQTSDYKSQASSWISCSSTTSPLSSRSTISIGDDIANFLNPQDSATITPLACPEVWANESNKYDCSTVFSYTSGQDLCATSSAYYAKAIPVIELQIAKQGYRLAAWLNVLFDGATDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC95</accession>
    <name>A0A9P6BC95_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_778698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158058">
        <property type="protein sequence ID" value="KAF9521459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC95"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="43988" checksum="EE241690FC992FAD" modified="2023-09-13" version="1">MQALLPALPLELIEFIVEHLANEENLDAVRQCCVANKQLVHACRKHLFGTIKVLQDSNWRKQLELSPDPTSHPIARFQQLLEENPSISSYVRELEILSTEAHDFPDNLAVLQYLTTVQVFTFRFSDGHRITAEWTWSTLPEKAEDSLVEFVRRNPLLSVSLSGIQGLPIKILRAFPPLESLAFLNLYLQENTFALAVQLNLQPGAFDLKELTDLSLNVGFRDNPQVTVRIVYALSLSATSLLIDCVADFRDFTCRRNLLTRLQPTCLATLKKIKLDFEVNYTPIFPPYGGLVDELLAISGVNVLEEIYISTQINIDSGLGMDSELWDQLDTVLSSGFPYFRTLRIDVLVGIFAPPEVAQGTQDDLETLFAGIFQWSKKNLSFTASLEAVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC96</accession>
    <name>A0A9P6BC96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_926531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158043">
        <property type="protein sequence ID" value="KAF9521492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC96"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPX" evidence="2">
        <location>
            <begin position="54"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="185" mass="21404" checksum="43DFF6DAA6851635" modified="2023-09-13" version="1">MPTTLNQPSKSELQSEFEPEFIPLRPLLRSRSFRSSVPATSTPFTPGKARKFAMKFSSSLKFNAVSEWWEEYIAYDALKKYIYQLEKQQVGRDRDRESHLSHSQILHQQQTPLIPDLESNSNEHTSLLPSSPPGPGTNSNTDALFTTLLNRELHKIESFYALQAKELLAELEELERDVELQDFWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E314</accession>
    <name>A0A9P6E314_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158019">
        <property type="protein sequence ID" value="KAF9521594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E314"/>
    <dbReference type="OrthoDB" id="3062477at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="544" mass="60652" checksum="53B82E8488A3E882" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3E1</accession>
    <name>A0A9P6E3E1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157990">
        <property type="protein sequence ID" value="KAF9521775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3E1"/>
    <dbReference type="OrthoDB" id="3270987at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="59230" checksum="ADC5D4939489D83A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3R2</accession>
    <name>A0A9P6E3R2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_151740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157969">
        <property type="protein sequence ID" value="KAF9521976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3R2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29419" checksum="E205A5D6D4D01FB2" modified="2023-09-13" version="1">MAPGQAKDAELTTQQKLIMGLYDVNGIPQEELEEICTARGACFETLAWFRKTTRVVDATTRSDIDLPSVYFVCITQSLLRYKYAAEVNSIQAVGGCLLEPLQVQLEAALELNQQSHVLWTSQAAGSWLDEELRDAKNVEVDDNARPQEAASALEEGEVEDLCFDAEEGEVSNVPDRRVDVKVARLPPVCTTSSSKWRSELLGVEDKQNLIITLTTHKFSPPKMGHTKWKTTGETSRDQAYTAAVHIRKASKAVGIKDHFMDNSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4A8</accession>
    <name>A0A9P6E4A8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Smg-4/UPF3 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_822996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4A8"/>
    <dbReference type="OrthoDB" id="18087at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12455">
        <property type="entry name" value="RRM_like_Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF3" evidence="6">
        <location>
            <begin position="27"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="56274" checksum="CF4542981782241C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4B0</accession>
    <name>A0A9P6E4B0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_864888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157957">
        <property type="protein sequence ID" value="KAF9522178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4B0"/>
    <dbReference type="OrthoDB" id="3267855at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="15"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="314" mass="35129" checksum="852C97B1DA7AD87D" modified="2023-09-13" version="1">MSGAVSGIPAAQQLIALLYYDYTLTWTREVQYFWKRKLSVSSVFYVFCRYALVANVVYPIALAKEISSLSCDNGYKICASLGILGRIGILSVWGIRTAAVFHGNKWIVFLFSSLGMSVFILNIAHVPYVVCAGSTPITHQILAIVTALYEVLTALFTTIRCFQLLRCKGNTSIPRDGIIFLVLQQGLLYFGFVSSFAFGVIVLQYIEPLKGTWVVRLLNGYNTPICGLMTARYLLHLREWENEHTCAFTTSKEDLASSIMFHQRSLRSFGGWTEEFMQDSLFNSGILENCSCDLSVEKSAVLLDDVSSLQYELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4L9</accession>
    <name>A0A9P6E4L9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4L9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="53" mass="5305" checksum="2FC92B7CC5D6B232" modified="2023-09-13" version="1">MTGDEAAVSALAGKATIMPAASGRLTSVSALVALILAASLEGMKGLERTFAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4T1</accession>
    <name>A0A9P6E4T1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_96963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4T1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9884" checksum="691D8D5A3DF49534" modified="2023-09-13" version="1">MYIECLHHHFTNCIIIIITMIVACFLLFLQILLYLPCILSLATTSLGLSNYALVLTCTSQLLFIPFHLPFHCLSLAHRTTVPYLVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5J1</accession>
    <name>A0A9P6E5J1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5J1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040317045" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="19812" checksum="F879EF6BFA9CBF66" modified="2023-09-13" version="1">MRVVQVLLSQFVVLESLAAVITPVAMAGKASLFDISRISARTPSGLETRPAGTIERACAKYLGGAGRDGFAAGNHGPVSLVHAARITSRTAFMISLALLPSLYIKTRLAALKFNAPLSTYVATLNHSYLMLRGIIAAHPSAFIYSEPLPGLRRRSWAYLLAFTLAKNKYSSLNTFAFNQVREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5J4</accession>
    <name>A0A9P6E5J4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5J4"/>
    <dbReference type="OrthoDB" id="3062825at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25020" checksum="B67CDE727A131D63" modified="2023-09-13" version="1">MRAEDSSNRRGGTDTTSSNNIAQQHLPNRGRVPGTGRNLAVVDEEANKENTSVFSNENGVDGHAKVGKTLHTSSKKKLEQSRLLGPLAPNHEVLSESNILMSDHEQTQDISLSKVPSQFSIKSRPLESLKLPVSTSSSASSNVVSPQQPYKYLLALLESCTPPMGNILDRFVKVECDKEEFVVAVSTWRPEAIRSFLERLPPSASGQRLSTMEVYILQNHWLQYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Y6</accession>
    <name>A0A9P6E5Y6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_698075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Y6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040358629" evidence="2">
        <location>
            <begin position="25"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="30538" checksum="4BFAE13D4F77FF69" modified="2023-09-13" version="1">MQFANKLRFAVLATVLLGCTQILAVEHIHQHGGHSVQHRHHNRHAAEIAPLNTRELEGYFVAREDVAVDARDQLLKPHGHKRKHRSRKQKVKKHAKSRKTSTAFALPASAEALTTGVSSTPSSSSPVVNSRDFDDAFELDARESHAKQAHKHNSKARKHRKGQGKHRTLEGKNHFEEAEETRQEGWQEFWFQVDQEGGQEVEQEGWQETRQEDFRANRRSDSYRTSLDSDESFHIGFSHFQKGRSDSGCQRRRLDDYEQDQPNQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E648</accession>
    <name>A0A9P6E648_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_910921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E648"/>
    <dbReference type="OrthoDB" id="3206554at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="167"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="36723" checksum="D28C696920F2F234" modified="2023-09-13" version="1">MERSLDIPKTFGALLLGGLFASFVSGFVTIQGVIYLRMYPNDAVGIKLLVLTVWLLDIGHTTVIWSALWSYLIQNYGDEGVIDIIHWNIAVTIVLTAVLTLLIHLFFAQRIFKLSKRNYWLTAPIVMLACLRLVSACGTTAEMIHLETFSHFVEQIRWIFTLGLALSTAVDILITASLFFLLQSKRSGLANLNAVIDSLIWYTFETSSLTTAGTIVAMICWLVMPSNLIFMGLHFVIAKFYANSFLVTLISRKKIRQGRRPSGSMEPVPVHLLDTRRPSNRTSDEDLGEQYEKEMAVRHSEQKAAKLQSTTEGQVEINVERSIQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E661</accession>
    <name>A0A9P6E661_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_698226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E661"/>
    <dbReference type="OrthoDB" id="2885385at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20874" checksum="D456ECEEE8DD5A78" modified="2023-09-13" version="1">MFTTCQPQPTQIPFDLYEVIVEELFQSNNDDSLKFLSLACHNLLGLCQRRIFRNITISWSTSKCIAQTSRLWFILSSSPHLLSYIRGLHCSISTLNPHPIALINIIQSLQHKNVEEFSFDASSSLSQDNCFVNSFIPTLQNFVGNTKIRAANIGNLAELTRSGFDKRFFLLADDYIAHRQWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6H7</accession>
    <name>A0A9P6E6H7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6H7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="295" mass="33556" checksum="F04D25B18DB49E04" modified="2023-09-13" version="1">MNCWQGPHFQSTFGHHTQEDILHLFGGLKTLFLMHVNLPAIFFEKLPPLRFLCLAGVHLASATDVALTPLSAFHPNAEIKADYASLQEVHRLFRRSQQPLPGYTILQINDIIRGLRNVLEGSQNTLTRLELQITYNCPPEDRYFDFGHYERLTSLHIRMNHYDDVWDISRIFKCIHLYFIAAAELCNPPTSMSHLVNIEISLFCSSTMQFSDVDLDKADDTVSTLVEGLGRLASSNITAHHPKLDSVKLNITLPTASSVDVERETINNYRNFVERCIKEAVEVDNQTLTYAVQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6T5</accession>
    <name>A0A9P6E6T5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_775381</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6T5"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="39"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="140"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="24287" checksum="6CA78AC68DEF5523" modified="2023-09-13" version="1">MNLDESTIDVGKLPTIAKDDETVQRKLEKAKRQPTSDRGVLYIGRLPHGFYEDQLKAYFSQFGDVTRLRISRNKKTGKSKHYAFLEFDSSAVAQIVADTMDNYLLMGHILRCKVIPKEEVHAALWVGANRKWRKVPLDRVTRVNHNKERTEEEQQRAAKRLIKRQEKKKQRLSDMGIKYDLDAVSYVSKLIFSAVLQLTLVQKMPKQATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E754</accession>
    <name>A0A9P6E754_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_738640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E754"/>
    <dbReference type="OrthoDB" id="3203937at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="11171" checksum="A67C01522C0258A0" modified="2023-09-13" version="1" fragment="single">FLHGCVNRNCDIYLDELQSDLENVCGAQASLSMIWKTLKRSGFQMKKLTRQAIERSAQKRAEYLLKIDTFYESEQLVFVDESAADRRTTYRNRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7C2</accession>
    <name>A0A9P6E7C2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_839385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7C2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16435" checksum="3C8CCF591E76ABBA" modified="2023-09-13" version="1">MPPVAKYVKRRQDAVRATLGKQFEVLGAFHTIPPYGGSDVQDRPMMNTAGCGFCFKVGEYEKFSSLKCEKLYLSVSESLLLLERVPKGRLVMATTSPDSTLATDVTRGLSTGDSAKTGTKKTIKSSKWRGVFITIQSLRHSLSGKLARDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7Q2</accession>
    <name>A0A9P6E7Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_647202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7Q2"/>
    <dbReference type="OrthoDB" id="2278929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="422" mass="44857" checksum="14643E1CC8A47FF2" modified="2023-09-13" version="1">MAASRSALWPEPTPAPFAIQDSRSPKRRRLQARQTIADQDKVATAMTQCQFDSGNEIISCFPTAETFIPQGDWASFVWNARRPDLLQTNLVNIYLFRADSQQQLLSFKDVVNPFGQAGVIRAQVNDTWFGEGGKDWSGKDINYPFYWLITRNDKPVDGTAVAQPIFTAVQTTALDSVARSSSSAAAAASSSASVMSASAASFSSVLSASSASVVASAKVQNDASHSSFPHWAIAVIVVLGFLAITATCLLTFLICRRVRRRQRSQQTSRNSMGSNSPMINRDGEMSQRYDTPGSPLLPPPSTAALASGGVAAGGPWHGHGSLHDGASTDSGGPFSGADAAIMAQAFRTTLKQPNFVDRPVEEGESPEQPEGEEAEGGHTEGIGNSTLSRELAAEGRDIRSVSSSRGVKVETTPGESGGTNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8X3</accession>
    <name>A0A9P6E8X3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_877564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8X3"/>
    <dbReference type="OrthoDB" id="10071171at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF2">
        <property type="entry name" value="GDSL-LIKE LIPASE_ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CBM1" evidence="3">
        <location>
            <begin position="492"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="528" mass="56249" checksum="0045FFDEBCB5B44E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E959</accession>
    <name>A0A9P6E959_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_909805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E959"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="473" mass="56417" checksum="BC4311AD403B9020" modified="2023-09-13" version="1">MNKFTEYLRQRKIDDAVRRFRRFHIKYEQKYWYQKTLEELDNIPSIRPGKAQDEMETAARMMLLADAYWALYCEHYESGGASRGQKLQLQAYDILWENLDPGSACSRTSPETWCRWDLNPTERRKMLDRCITFVEYSRQQNWPSGIPLVPDMLEEVVLCSLRNGDYSDDVKALQLMWVNRSFQDSFEKDYVLSCTSRTICIHLERQEWDEAETVITRYLKSHRDMYAEVKAYANLGEVQIRRRQPVKGEATLRKGMAFDRDDSDLWSGYLLCREQLMGLYMQQKRWNEAKEIGLALLRAREDQISGKLEPMLWEKRDWNKATQKAARVIEMNRWRAVERNKFVLSQDEASIDSKVYYLHMLYNNKRQLAVVHMQLKQYNEAQQLLEGLMEDKMHMENPILVASKEHLVTLFIESGQPSEAEKRQEKTIEEMTERFGYDSKKLIPNLERLADIYQENNHLGMRHHVKVRLLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9E3</accession>
    <name>A0A9P6E9E3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_885714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9E3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="22143" checksum="66CA4D3A8C02593B" modified="2023-09-13" version="1">MSAPRVYVGNLSWNTTEDIETHILSDFGFGVDWERESIPSTEREDDDRRPNDPAHEQNREEQERKERQQRIEAEKTKKLLMKQLNLLVLTKMVAGGVFIVRNMRSLVLAAILLALFLNLLGWFIMTGLFVTFLIYLLLIIHTPLKATFSSQVQFFGNHVSLAPNERHQCQSRWISTSLIQRLRYEASRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9G5</accession>
    <name>A0A9P6E9G5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">B-related factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_860671</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9G5"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20553">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000002">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000007">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="12">
        <location>
            <begin position="87"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="12">
        <location>
            <begin position="182"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="288"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="504"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="643"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="666" mass="73697" checksum="53EDBEBEE54B8E27" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9T6</accession>
    <name>A0A9P6E9T6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_548147</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9T6"/>
    <dbReference type="OrthoDB" id="3267106at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040131257" description="CFEM domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="8">
        <location>
            <begin position="47"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="20780" checksum="13A6398AA0BFC8A8" modified="2023-09-13" version="1">MFRSPLLVLVFLEGFLFAWAQRGVSLIPPPISASSSTSASATSSTSSVANSSNSAALSSTSSTTAFPSLSTYSACVSNCLQTGVARVNCSSLTDVNCFCKSPTFPNEVDGCILSDCPSELQSAQSLAQQFCDLASSSPSLSFIPATSTSSSNTASTSSTSSSSAPSTTTSSLGLRNFEAQSWNAVVGLSILLGGSLTGAGIWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9U9</accession>
    <name>A0A9P6E9U9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_796706</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9U9"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9525201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="455" mass="49839" checksum="BEE52F2605F394D1" modified="2023-09-13" version="1">MERIRWRLASGFFAYFMCGWADGVTGTVLPHLMADFHIGFALSSSLYAGSTIGFFFTTLSIEVFLHFLGRFDLSKTHWSWIPEFTFLGPCHRRKTPKSIGNSPSQARFLSLLIASVAQAIFLVMMGSRGSFWVVFFGYSVAAFARSTLTANLNTYYASGYQQSLGFAFGFWSFGGVVSPIVCQALMAKGIPYYQFYFGSLVLSGFNIALLVATYIPTPQEFAKDRKAAITASAKQELWPIPTSAIHPPLSIKPEVKGKSQALRAVISMPPHWALSLFAMIYCGCETVTQAFMASFLLGVRNADVKSAGYVTSGFWGGITVGRLIWGHYTPKLTCSQRKWMIEACIVLGLVMQITIWKINSEIQNSLAASIIGVLYGPIWPALLTLTTDILPPQVYMASMAITSAFASIGSSLFLFTAGLMSSAYGIYTISYMTISLASTIAIFWASLPSGDPLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAI1</accession>
    <name>A0A9P6EAI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_772039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAI1"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="20096" checksum="EC767EE14B179D8D" modified="2023-09-13" version="1" fragment="single">NLFIAPPFSSRDDLLEVRNFSLDDARRPYDDLTSSPYHVEPYPQRYSHDVPVLDTPARHKVEGVYDRFLMATSGVKRLGKGYQSESLAASTNKTSGGIGLGLHVPQNKTRPFYSTRKPMPPPVSSEDLRRMTASVDELGNLTHAAENQDDSLPAKDGFMRKAMKLMVPKANSSKRMSRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBE8</accession>
    <name>A0A9P6EBE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBE8"/>
    <dbReference type="OrthoDB" id="3596986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="470" mass="51875" checksum="1DC3644814903DEC" modified="2023-09-13" version="1">MIGRFTGGFGERCFNPLGKTGRMLGEEVDEYESEVEAMSVGFDDPENDGRSLVSGGWGVGHDGSAIEIVNVQFVERGTAQKGPGLGRRNRSQRLLEYAERRAAVLGQSFAPAVRLAGRKRRRHWDNWPVQPRRLPNAAVLDVIHDADEDDLEEELRRPTKKPRHEDEQKLMDVCTMVFGMGASADLLVGYKYIPDLLQNVLFPTSPASSPSHKRRRTDDDDIEMMDLEVETPVVAVREPIRPVILETTKERYLLSPSADQPDANSGRSYDIALILEAEVVVEEEPPVEADAIEGKPMEIEPTPSADVAPEAQVETTPKPGSPKELPPAEPIASMEPKSSSKEPEAKATTPIPSPQPLQHATSSDPLRSTTSPVHSPEPTAEDDAGSAPPSTPPPETRQKTPTILVEDEIIKPQFAVQVLQQNLNKNMLRFAPEGVYVYDGSGDAMGMETEWVIQVKNWKWAPRSSKEKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECF6</accession>
    <name>A0A9P6ECF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_857152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECF6"/>
    <dbReference type="OrthoDB" id="2576477at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="382" mass="42045" checksum="857A2779FEA785E3" modified="2023-09-13" version="1">MAVADDTPNGPSPPGLPDIPESAITDPPPPYPTPHRQRQSRSNRPHARVQPTQLVTQHSQQLSNESQSDYETPLSPYTVSSGLTDEDDGVPVGAGPGGGAEESAVETSPFLSPNSNRRAGRARSFSMSSTASAAESMAHTVLSLFQPEDDMCYGDGHIQLDPDDHMPILSSGRPGGLFSAITWKRYFRPMRMRAFYRPLMHLTVINFPYALAAWIYLFVFTVSGTTLLVALPIGAVLCFFNLLGARAFSRGELYLQTRFHAPLAHPPPHPPLPIFARYREPTNEELENGTVAGQLRRGGQIREKSFYKNTYAMFTDSRSYQALFYFLVIKPAITLLISIGLVVFGIPLFVLVLPAPAVLRATRKIGIWQANVAVEGLYYAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECG2</accession>
    <name>A0A9P6ECG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin p58/p45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_858044</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECG2"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="20"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="51855" checksum="14C51F2E224AF566" modified="2023-09-13" version="1">MAFATNSSAFGIKPATTGTSLFGQQQQQQVQQGQQSSLFSGFGQQNPQQNQAQPTTSLFGQPQQPAANNAGGSLFGQNQPSTTGGGLFGQSTQQQPQQGATGGLFGQPQQQNQQGTGGLFGQTQAQPQPAGGGLFGQPQAQQQGSSLFGGGSLFGNPTPQQQQPQQQTGGLFGSTNNQTTNALRPQATLPAGAFGASTGTSTNTFGGLFGNNIQQQPQQQQQQQQAPSIFGNNGPPQNTGLNTFGHQSSLNASSATGPPPFTKSTKFNDLPDHFKSILENIDTHIQGRVQICKDLQQRKLGEEPTKGHEAIRNIQKDLANTAATIRNDLHVTQDLKAKVDQAVEDTIVATRIIDGFRNPQSGHTYLKDHSSFPLEYFTRVTDQMKQRLDWYKSTIEQIERKLASATSSTQTPQNISATLQAQHAIFLTLASKTAAVDLELQKIKTLYTQLWRAKTGSVRDPFGDGVKANEKNTGDFGLSQLNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED71</accession>
    <name>A0A9P6ED71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED71"/>
    <dbReference type="OrthoDB" id="3267661at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18155" checksum="58BACE0660824669" modified="2023-09-13" version="1">MAGATPTLIPREQLFPLLLPKPPHPFPTPLQRRRVYGHLNAFRDLQREMDDLSDEDNDVEEAIQLVGKRGYTTYIPIGRSLTQHEERNDDDDSDADTSQQSGNEQQSPASEADAENESTQDLDASMDDLDDDGGGESDEEEDLDEMLEGNTEDYEDEPSDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED99</accession>
    <name>A0A9P6ED99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_434526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED99"/>
    <dbReference type="OrthoDB" id="435460at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="54041" checksum="2A37616E264F80DA" modified="2023-09-13" version="1">MDEGEFHYVVELDSDGQEMNSATKKNKRKRKRGSSSTPLSKPAKKPRPSKDSSSILDAKSKGKQRASEFEHVDSDQPQFGDANGGYELNALDDDFEFREPGPSFQRSPEQTLVENVSRARQATEPFPTQETLVDEGPSSHRVSAFNPISHSTSANRRHSAYTTRSPEGAIHVRSPTPPPPAQPRKSVESAASAYQQVRPVSPGANSPLLVEPPVIKPRPKPRPKKVVIRPVVEASPSLPRYEAPYRNTRSRSRSVEPSVQPPAKRRKAPKKKEPIQEESEPETVEERPETPQPELKLPTTETVEEEMDVENFLTNADDSNNSIQGGLVSERAASLETDDAQTRDDLFAAPLPLSIPQPPPLRAPSTVNRIRPQAALLAYEATRQRPRFSLPPPPRASVPLPKYTPEAQSRYGSRPRQSEPSPATFRLPEPRTPAYNAPRRAPSVSSDEPVPVPGTRASTIKKEKEDLEKHSPYRPPAGTRADMILRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDP0</accession>
    <name>A0A9P6EDP0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_937061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDP0"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040536128" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9526899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="490" mass="54942" checksum="727B28D60AB1E775" modified="2023-09-13" version="1">MFKFLNALVFGGVVTVWAFQVQMTPETAFKSYDDGLFKPIETLSALSENAFTTMGHPNFPNYSVRIKKSSFCDKTVKSYTGYIDINAHHLFFYFFESRNDPDKDDVILWTNGGPGCSSTVGLFMELGPCRIVDEKGPKFHPESWNSNSNIFFIDQPADVGYSYADFGDPISNSHDAAKDITAFVTIFFENFSKFKGRAFHLAGESYGGRYLPIFASDIYDHNTKLVDSGLTPINLTSVMLGNGMTNVHLMLEGYYKTTCSADGDPGIYDISTCVAMKKGLPRCLKWYKESCVDQFDHINCAAADSFCELLLAQPYYDAGKNPYDITKSCSPEELENSLCYPALEHAANYLTRDDIRHKLGVDPAQNFTRCSEPVANAFIASLDMFQPTHLHVAALLERGVKVLVYVGANDWICNWLGNEAWTLDLEWSGQEVFKKQQLREWQVDGKDAGKTRSTGGLTFATIYGGGHMAPYDRPKESLELVNRWLRGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDY6</accession>
    <name>A0A9P6EDY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_768129</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDY6"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001389">
        <property type="entry name" value="ATP-dependent DNA helicase RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="40"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="262"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="597"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="630"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9527696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="728" mass="80861" checksum="ED461FE8EA0EB370" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEV4</accession>
    <name>A0A9P6EEV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEV4"/>
    <dbReference type="OrthoDB" id="3174109at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="513" mass="58800" checksum="3D134A6774CC0E90" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF07</accession>
    <name>A0A9P6EF07_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_766970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF07"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="41"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="293" mass="32648" checksum="D1B114507B13EF2F" modified="2023-09-13" version="1" fragment="single">MAKYAGGGHQDPSTCLEGTRTTALEKIDKWKRKTLEEENPKMMWLTGSTGSGKTAITQTVYERFKAEELLVVQTSFCRSTGCTDPKYLPLSIAYQLAVANSSLKAAIQAVVQADPAVIDASIDAQLQRLVLEPISENASQIPMVYVILDGLDECGVEDQQIHIIQLIQSIVTEQHLPIRFLIASRPESWIQTTLSSPSAPSLPTVFLNQDKEADSDIQLFYETEFKRIHNDPRHAHSMTSAPSPWPSTENIEWLVRWASGQFIYAKMVTRFVGEPGHSPIRRLEIVLQPNSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFC2</accession>
    <name>A0A9P6EFC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">fumarate reductase (NADH)</fullName>
            <ecNumber evidence="10">1.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NADH-dependent fumarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_854264</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="10"/>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFC2"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000007">
        <property type="entry name" value="NADH-dependent fumarate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="13">
        <location>
            <begin position="504"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="581" mass="62354" checksum="8CA483F0F7524227" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG40</accession>
    <name>A0A9P6EG40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_347492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG40"/>
    <dbReference type="OrthoDB" id="3050922at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="62207" checksum="AF06191BF2865E8C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG45</accession>
    <name>A0A9P6EG45_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_854738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG45"/>
    <dbReference type="OrthoDB" id="2748942at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="8951" checksum="C47A63D64A3ECA82" modified="2023-09-13" version="1">MCNFRRVSDYFPRCEHVIARPEEYIQCNSRYCKFSPQHPNNCTGDQCKCLKSRQYPETYQLRKEGTCPSCTAQGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG73</accession>
    <name>A0A9P6EG73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_314464</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG73"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="9"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9528516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="35543" checksum="965FBB449F517AF6" modified="2023-09-13" version="1">MSVDDETSGWQLTESDPGVFSELLKSLGVPLIVDDLYSLDADSLAALQPLRALIFLFKWIPTSSDSTSQRAGTDDPEFAGFFAHQVVNNACATLAVLNALGNIPSLESGPKLSELLRFSADMDPQTRGLVITGSDWLREMHNALSPPSAFSLDGLGLPKKAEEAYHFVVYLPVMGALYELDGLKPHALRHEAFDDSGEGWLKTARQVIEARINTYPVGALEFSLLALREDPLPSLRSQLDRAQAPGQSPAANELLAKISNENAKRERWAFENSLRRHNHVGLVQGLLLALAKGGKLGVAEESAKKAMKERIEQRRARGADMDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGE6</accession>
    <name>A0A9P6EGE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_894448</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGE6"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040544722" description="Hydrophobin" evidence="6">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="9886" checksum="8BF77C482F75594A" modified="2023-09-13" version="1">MFSRLSLWAAVVAMTLAKASVLPRQDSTCSTGQLNCCDQVGDVHALGLTNNSALIGVVLDPITAIVGVDCVPVSVLGAAGGSCSAQTACCSGNTYASIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGQ2</accession>
    <name>A0A9P6EGQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGQ2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040190541" evidence="2">
        <location>
            <begin position="20"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="13348" checksum="FC2DDDC56F790BFA" modified="2023-09-13" version="1">MKSMIFFATLCSVLAFVFANTPETGASTSSVTSVISAGGTNGIQTTSVAVGAGAPAVSSVSGAADNVTDVSHNTGIGPVASIVNSSTNPAKPSSASRKSSDTSTSTNPPKPTKSNTASVNSAAGGVAALLVGGLTIAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH14</accession>
    <name>A0A9P6EH14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_883297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH14"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="21656" checksum="B7831536E25D3D1A" modified="2023-09-13" version="1">MPIGYLSGFISRIVDLYRRCHGTNIEAVQTAAEEPEISATPSTPPAQTPPRALTRTRHTNADISNNLPPLESLFANIMSRYNSTNQGLALPALPPPSLQQGRQIYPSFHRFRRDLRRVAWALVTIYIPSMLRSVTSRRGDPPSRNSPQRSRYQLVSRAVGRRILIPAAVFLFAASLAVVVRLSGKRGGSKGLKRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHC0</accession>
    <name>A0A9P6EHC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_853417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHC0"/>
    <dbReference type="OrthoDB" id="3248974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9077" checksum="D4B6E34860294DC9" modified="2023-09-13" version="1">MREHAIASGQSEKRFGFVTTGLDSLAFGHGRHVCPGRYFAASELKLMMAHIVMNYDVRTIEEGVGPEDLYTTGIKAFCDLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI97</accession>
    <name>A0A9P6EI97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI97"/>
    <dbReference type="OrthoDB" id="3160134at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="393" mass="44466" checksum="2B17B3383454F115" modified="2023-09-13" version="1">MPSAPSSPIQPSSESAHAELARTKRKLASVEAKLAQATGKKRKHVSNINLGRGLSRLVSLFDSLSALVDEADRRFAVQRGDIEEEEEVDEIVSRERDRCFASYILLLRTVPRVKDLIEDSEQEDELTDLLDKLQHGANEARRDDLRRILGELPQWLNEDFTPERAFSLKNRRDRGLQNAVTGRLLCPISYNWDDTAVRTSIRNGTISIADDFYLACFYPRATGNVADVEARFLRSKLLVKAYCAIFTSPSSADAFEEESEEGPARKRRRVDAQKKITKSTVADLIGMEGKVTPRTIAHAAVMLAFNLTNCEHWRPSYNGFSYHSLYNFIIDFFEDVHDPITRRKVDQLLVWWNLQVFPDHVATVSDSQKSNDKLKRQRAQRAAASNVAANPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ47</accession>
    <name>A0A9P6EJ47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_905992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ47"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="611" mass="66946" checksum="7DECE6360A44F944" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJV1</accession>
    <name>A0A9P6EJV1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJV1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="11470" checksum="72D59762606245CE" modified="2023-09-13" version="1">MDHPTADNRPVKDHRDRVLVPYSIASPHDEIEWLIFLKPEVSVQDFMSQYEFTESNIVSYIYCGFSARIDDERLEKIRANPDVRMVCENKRHIVSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJZ8</accession>
    <name>A0A9P6EJZ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJZ8"/>
    <dbReference type="OrthoDB" id="2748218at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="13130" checksum="DA14EF89F624BB22" modified="2023-09-13" version="1">MSIQNSEDGQNTSNHQSGECYVVQVIIRQAYKNVVKELTAFYLSQFEITKAIESILYAHILAPLPEEVRVEGSGFVLRGKRQPWVYGKTLELSWGQQNIKACDEKWSFEFEVADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK11</accession>
    <name>A0A9P6EK11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NBP35</name>
        <name evidence="12" type="ORF">CPB83DRAFT_922123</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK11"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904564">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly scaffold complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000427">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="78"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9530354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="34608" checksum="0F67674AB009857D" modified="2023-09-13" version="1">MIATQMAVPAPDPKSIPANAPEHCPGTESDLAGKSEACAGCDNQSICASGVTKVPDPALPFIKARMAQVKRKILILSGKGGVGKSTFTAQLGWAFASEEDTQTGIMDVDICGPSIPTILGIASEQVHSSTSGWSPVYVQDNMAVMSVGFMLPSSRDAIMWRGPKKNGLISQFLKDVDWGPLDYLLVDTPPGTSDEHLSIVQYLKESGIDGAVLITTPQEVALQDVRREIDFCRKVGIRILGLVENMSGFVCPNCKGESQIFKPTTGGAKKLAEDMGVELLGSVPLDPRIGKSADYGVSFLDEHPDSPATTAYLDIIDKIKEILGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK67</accession>
    <name>A0A9P6EK67_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_167332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK67"/>
    <dbReference type="OrthoDB" id="58416at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="27659" checksum="D6C9ED142C1C2E70" modified="2023-09-13" version="1">MSSEREQYALLPVPWSPETNFKDHVATLATEMICVHNSFIRCLNNMYYYAPRVKKGDEASFVGYCLMFLNLLHNHHSIEEELVFPVLQTKLDMTPNIEQHKSFHEGMDNFERYLKDVQDKKEVYDGDKLVGLLDGFSYPLVEHLNDEIPTLSPERLAQLDKAQFEGVCKELEEHIKSSSMTTLHSFITVHHDSRTAPSWPPAPKLISWFISNVAYWRHSNLWKFAPFNRHCQPQEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKI8</accession>
    <name>A0A9P6EKI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3271284at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="660"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="889"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1205"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1245"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="707"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="731"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="785"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="830"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="906"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="947"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1208"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1245"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1282"/>
            <end position="1296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1392" mass="150818" checksum="5A9D822E27999591" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMC7</accession>
    <name>A0A9P6EMC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMC7"/>
    <dbReference type="OrthoDB" id="3190489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="421" mass="47137" checksum="1A8A47389A32E187" modified="2023-09-13" version="1">MQPEHVPLIARLPLEILETLVDYAPIETQLSICRVSKLFQSLAVRSIYRNLSLCSPDIAVDCCRTLTSNSSTAAVVRSFCIVYKNFPLAAKPPLPSYYATIQNALHSLSDLMILRLLVHDPSLVSLLTHSVFPSLRQFECFLTPTTCLITFLNLHPNIDYLQVSPHEDTEEPPLGGEVIVHPRTLLPRLQYFSGNAQSIGLIEGTQKLKAAFLTWHAVDTDPELVLAALGRGNRASLNLLSCTRRGWNLDLFETVSTHVPEILCLHLSNILLVDSRPTETYLQAIRAFLPRMTRLQRFCVNCIDYFEMGSVTCQLDQDFSTVTEWGAACPSLEEIGLPHSQGLSWYRLAGNSWLPDPQHPLGEQWLSKSIARRRLAWGSILNGLPESQKRASGHPSEFGESVASIRTHLDIFLRESRTIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMF7</accession>
    <name>A0A9P6EMF7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMF7"/>
    <dbReference type="OrthoDB" id="3121373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30086" checksum="8D94D4E149BF9CA4" modified="2023-09-13" version="1">MQSTTPQTTTPSRKPISPSFGYLIVGRPLEAKFQSIGQYFHVSYLPYQTSENAVETLTGKDICLWLGDAVDTEILGYIIWPGEGILTLGEGLNSGKPSRMVKLGAQSGSFESGGSNANIIMQELLYLGPRPCVLFVRSLMQEDFLQEEAARLSFRKRAVEWVCDLESFLDAAALSGDAVQSSQIHHWHRKVMIGLQTADRTSFLFDPTRFLVGMLKHLHQTLLSVNRLDVNKMSKTGGPVLVPMCFVRSWKENVVDASTNDLTVIHAMMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMN5</accession>
    <name>A0A9P6EMN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Voltage-dependent anion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_761085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMN5"/>
    <dbReference type="OrthoDB" id="1099at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000319">
        <property type="term" value="F:sulfite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051629">
        <property type="entry name" value="Sulfite_efflux_TDT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686:SF1">
        <property type="entry name" value="SULFITE EFFLUX PUMP SSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="401" mass="44619" checksum="60C64006FFA304E5" modified="2023-09-13" version="1">MDIFVGTGSVSNLFLAFPYAHGSESMLVFSLIFFFLNLFFFVFFLSLSLAKYFIYPAKWHSLWKNPVTSLYVGCFPMGATTLINVAVQVGHERYRIGGEGFLRFIWAMWWLDVIVSFLCCWIGVHTMINKQTHSLDVMTAMWLLPVVTLIVASSSGGVVGNSLQEYSVQDSLRTTTVSTFMVAVGLSLALMILVIYLQRLITFGLPKGPTVLSVFLPLGPTGQAGYSILLIGENFRSLLPNLSDRNSSILGVETTPATIQVICVCVAFVLWSLATMWTLFALMAVYTRLQETKIAFRMSFWGLVFPNGVYANLTIQLGNTFDSPAFRIWGSIYAAGVLLLWLSIFLRSLAELKSFFKSDQVLLPQMLDSRTSSSHLSLPTTDSCGIVNQIQTLDNLTSKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMV9</accession>
    <name>A0A9P6EMV9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Zds1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_85663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMV9"/>
    <dbReference type="OrthoDB" id="5589766at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040206">
        <property type="entry name" value="Zds1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013941">
        <property type="entry name" value="ZDS1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089:SF1">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08632">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01327">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein Zds1 C-terminal" evidence="2">
        <location>
            <begin position="526"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="723"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="774"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="937" mass="103484" checksum="7F5D50D0663DBA1B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW6</accession>
    <name>A0A9P6EMW6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_579943</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW6"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000001">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9532736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="218" mass="23910" checksum="7EE51BF8FE15AF44" modified="2023-09-13" version="1">MLVTKNLAPGESVYGEKRISIEGNVDGTKTEYRVWNPFRSKLAAGVLGGLDDIFIKPGAKVLYLGAASGTSVSHVADIVGPEGIVYAVEFSPRSGRDLINMAKKRTNVIPIVEDARLPNKYRMLLSIVDVIFADVAQPDQARIVIHNAQSFLKDQGHIIISIKASCIDSTVPPETVFAAEVETLKKSNFKPLEQVTLEPYERDHAMVTATYYRHGKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENH5</accession>
    <name>A0A9P6ENH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_880819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENH5"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="56"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="567" mass="65448" checksum="80A8949FC31D5C21" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP60</accession>
    <name>A0A9P6EP60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_629269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP60"/>
    <dbReference type="OrthoDB" id="2564485at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="48437" checksum="CDBBD489905A93FE" modified="2023-09-13" version="1">MVFQIEYPVTRFVGGHKWLGPVSYLGAFIAIVMLTLVNVALVGYETVNLFSEDYNISISHWYDTFMPYRKAKPGTLCEPHLLNIGDHFTTNYTVFEWVVQSVALSGIPVGALSGVPYTGNLLNDCDVNMIYMNGDMARYSVQFSVVVSCKDNDSEVTAATSFTVSSLPGVMGDAFGVVSQSNSGALSNARPIVLSQLINNAAIDLGIRVQTALAVSNGATPIALSTLSSIDNFCPASLSSSDCGKQRPNISFIQSVSITPNNTLSQSFSTKLAANTTVIDALTEAPLLNLLQTVYAAARIDLGIDSPNNVFLHKEALPLVLNKTFPVTLNTPASIPAALTSNLYLDFEDPGQISPGWENVLPVEVAGPAVIRVLYLCRYQRRKSGGSLFISVLVAVLSMFTSGWGIYTKILTKWAKRSPGSNSCENHQFKEPYRTLEQSATPDEKFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPS2</accession>
    <name>A0A9P6EPS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_831605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPS2"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="385" mass="43188" checksum="EB76CBC988F1F0A0" modified="2023-09-13" version="1">MTETESFFTPASPPRTKLGAYRVLSPNAGAHVSPLVLGAMSVGDQWHKLGLGSMSKEESFQLLDAFYDKGGNFIDTANNYQDETSEIFIGEWAEKRGIRDHLFIATKYTNNFKRTAKFDQKIVYAGNNAKSLHISVEQSLKKLRTSYIDLMYLHWWDWSTSIEEVMKSLHTLVLARKVLYLGVSDTPAWVVSKANQYARDHALTPFVVYQGAWSVLERSFERDIIPMARSEGMALAPWNVLAGGKIRTDEEEERRRQTGEHGRKVMGSEWERTEDEKKVCKALEKVASEVGAKHITAVAIAYVMQKTTYVFPIIGGRKVEHLEANLEALSISLTQEQIKYLESVVAFDPGFPMTMLGDGTGPNQLLSLTAQVAPLPLAQPLRPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPW9</accession>
    <name>A0A9P6EPW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_873755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPW9"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000028">
        <property type="entry name" value="S9 family peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="6">
        <location>
            <begin position="544"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="762" mass="84753" checksum="C842471F7382B3A7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES13</accession>
    <name>A0A9P6ES13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES13"/>
    <dbReference type="OrthoDB" id="2564568at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040320045" evidence="2">
        <location>
            <begin position="21"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="18316" checksum="4640A73A80399432" modified="2023-09-13" version="1">MVRLTQAALIVALSLPAALANVHLIARQLPGLGGDSIPQACADKCQAFTTTVNGNPSCLSDLACLCDAKVAQGLSDCVTCGYAISPDLLNGTTPDALIKQYSDGCSAAGHPVTIASSAASGTGSAGAGSATVTKSGSGTATGAGSGTTAKTSGTSTSSSSGSSASAGSTNGAVANTWSMVGAVAAVAAGAAAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES51</accession>
    <name>A0A9P6ES51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_230326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES51"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040271471" evidence="2">
        <location>
            <begin position="21"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="16483" checksum="9FDD784423E8BC29" modified="2023-09-13" version="1">MRSQSLMSIILLASGSFVLSLPVGQLYPRDIGDTAVLEARQHLKPAPVKGVKVKPRDIDEGPLLEARQRKLPQNPKRREFIDSELLKARQRKVKRDIDENALLEARQRKLPQNPKRREFGDSDELEARQLQPLGKPAVLQPPSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESN4</accession>
    <name>A0A9P6ESN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Golgi-body localization protein domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_781585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1562405at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019441">
        <property type="entry name" value="FMP27/BLTP2/Hobbit_GFWDK_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019415">
        <property type="entry name" value="FMP27_SW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019449">
        <property type="entry name" value="FMP27_WPPW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01214">
        <property type="entry name" value="Fmp27_GFWDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01215">
        <property type="entry name" value="Fmp27_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01216">
        <property type="entry name" value="Fmp27_WPPW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 SW motif-containing RBG unit" evidence="4">
        <location>
            <begin position="1272"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit" evidence="3">
        <location>
            <begin position="1393"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 WPPW motif-containing RBG unit" evidence="5">
        <location>
            <begin position="1789"/>
            <end position="2231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1960"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2552"/>
            <end position="2590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2826"/>
            <end position="2911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1968"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2577"/>
            <end position="2590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2888"/>
            <end position="2902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2911" mass="324186" checksum="7C4E9D59D2758C79" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET05</accession>
    <name>A0A9P6ET05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_872460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET05"/>
    <dbReference type="OrthoDB" id="3251634at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040231042" evidence="1">
        <location>
            <begin position="24"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="177" mass="18910" checksum="85D482ED9AC6130C" modified="2023-09-13" version="1">MKFGSSILLVIASLAVSLGAAAAAVLESRDWIGDIINQIGLGLVTDLNAYITTQTLVDNKISIDVNLKSPLIIELTIDRIVSSAGLNGTIYSTFDHTFEKPVVLPPQKKVNTGRIPDVLLTQGALASLDIIQYGIMDLYSTDVYVRALTIDGNLGVPITIKGLKQLAVPANYTLELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET64</accession>
    <name>A0A9P6ET64_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_802825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET64"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="32"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="502" mass="54033" checksum="3F45F95527BC7E0E" modified="2023-09-13" version="1">MVTETSLPEPRIGYSSTTKSDQRKLSPLPKFQLFIITLINLAEPLAGSVVYPFINKLVRETGITKGDEKRQVIMLELLQESGFFLAECLTVVQWGYLSDRVGRKPVLVLGPLGLSLAVLGFGFSKSFWSLVAFRCLQGAFNGNIGVTKSVIAEITDSSNMAHAYAVVPFAWSTGNTIGPLIGGYFANPADRWPDKLSRIQFLKNYPYFVACAIVSFSSFAIFVVTLFGLKEVSVISHRRQNGASDNSVITLSEETPLLVSSDGAISYDERRLRNAEAVSGAVINGPAAADPLRTLLKGPLSTIFVNYGVLAFLDMCHFALLPLMYSTSPHLGGLGLDPYHIGLTLMTFGVINAFVQSLILGPLIRKYGAKRMFQFSMSFLPICFSMYPIMASLSRQSGGVNAYIIICIGIQVCCQTMGLVAYGSCQILLVTGVPEQHLGVVNGIGQMVGSGARAIAPTVASSLYSASLSNHLAGGNLVFYVLIGLAVTGLACSTRLRDVKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVB8</accession>
    <name>A0A9P6EVB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">40S ribosomal protein S9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_842054</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVB8"/>
    <dbReference type="OrthoDB" id="1697570at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000021">
        <property type="entry name" value="40S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="10">
        <location>
            <begin position="6"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="107"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="164"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="22364" checksum="8AF1F221D94CB9E9" modified="2023-09-13" version="1">MPRAPRNHSKTYKVPRRPFESARLDLELKLAGEYGLRNKREIWRIALTLSKIRRAARELLKLDDKDPKRLFEGNALIRRLVRIGVLDESRMRLDYVLALKIEDFLERRLQTQVFKSGLAKSIHHARVLIRQRHIRVGKQIVNVPSFVVRLDSQKHIDFALTSPYGGGRPGRVKRKRAAAAAKKEEGGDEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI53</accession>
    <name>A0A9P6JI53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI53"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="192" mass="20978" checksum="90E62DB99790FFDB" modified="2023-09-13" version="1">MPPKKSTSSKAREIRMRNMELLTPPPVSVPTSGTKAQRTSLHLIQSSNLTSTAMLLGHFPNDYSRAKSPGSQVSASSNVPYSAHTRLKVAEERQAKLLSQSQPCREFLTKPSLYNLDRFFEPILTEVSPAVLLNAFDALVQNLYGESTRRSVAVSTKISNAAVVAATQSRGESREVLASKARVSKENCSEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJE6</accession>
    <name>A0A9P6JJE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_863968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJE6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040277192" evidence="2">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="9252" checksum="906697C7C5752802" modified="2023-09-13" version="1">MRTSAIFAVLAAAVVSVVAQDPTTSANSTTAASTSSSGAPATSSSGSASGSATGTSASNSSSSSAAPTTTESSKSGTASLNAQGLLALMSIPAVVYFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJP1</accession>
    <name>A0A9P6JJP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJP1"/>
    <dbReference type="OrthoDB" id="3046363at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="63444" checksum="EAFBAF436F26F992" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJX6</accession>
    <name>A0A9P6JJX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJX6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="25256" checksum="2B97BB7BCDC09C5A" modified="2023-09-13" version="1">MESISKLLGQDKRRVYMALNTKIVVDDELDESRFNTTILIAPKEPDRKTHSVDTLTLQLRRHMGQREGVRKWMCDIYDSPARSSALVGLLFFGKISHFVDTAKISEIVKEIPSQLDAKFEESRWYRHHWACAVIDALISNKILPELPPEVTSETAWQKACEFLEEYAKTKELGKSEDPVPTCDVYGNEIPSSFDPVTPNPYLPIANKVIYPSYPDPDEELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK43</accession>
    <name>A0A9P6JK43_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_862219</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK43"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.310:FF:000002">
        <property type="entry name" value="Sulfhydryl oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040269063" description="Sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="24"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="74"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="216" mass="23843" checksum="4F0C1963FA255166" modified="2023-09-13" version="1">MLSRFAKSLIFVIFAMLLLTTIALKHPPARMYIDPWTGQLFGEGGVEKTLNSEENWTPVIGGVKGNVIMGKLGNATAKAELGRATWKLLHTTTLRYPEQPTPDEREALSSYFYLSSRLYPCGECAAEFQQLLKKYPPQTSSRRAASLWLCFIHNEVNQRLKKPEFDCAHLSEKYDCGCGDDKKSEKLGSSPETVDSAGAASFSRDLLTGAGMVRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKM3</accession>
    <name>A0A9P6JKM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_862086</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKM3"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046098">
        <property type="term" value="P:guanine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="47"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="450" mass="49995" checksum="B9582B50D0267983" modified="2023-09-13" version="1">MLITISVPQAVDDNGLISHFEPAASDASSQLIEEASTPITLIPTGAFLLPAFCDLHLHAPQFLYQGNGLDLPLMQWLDKYTLQSEARLDANPTLARRVYTQLASQLIENGTGTVLLFGTIKVETNLILAECMLSAGIRAFIGKLSMDIDISSPDSRKLTYVERNASTALEAVTLFLEGCGSLVNQLPPTRRLIEPVLTPRFVPTCTNELLAGLGNLSEKRNLKIQSHLAESKEQAERVRSEREMDDINVFEKANLLTSRTIQAHCTFLQKPNFQHLTQKGTSIAHCPLSNSYFSEEPFPLREALDCEVQIGLGTDIAGGYSLDIMSAMRQAVMVSRMREGVRSMDASRSSDTKVSIDWVESLYLATRGGSRALGLEGIFKIGAPFDAQEVAIYDTYTNRGIGALNYFDLESRLEDERIVLDREMVEKWWCLGDGRNRRHVWIQGHPVKDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL25</accession>
    <name>A0A9P6JL25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL25"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="339" mass="37675" checksum="F7402DC3C52664F1" modified="2023-09-13" version="1">MATSARSAIIDDSSNLINYQGDTWYEYPVVYDNQYGRFGPPMRGKMHGTGQSASLSFAFAGTAVRVWGPNELASNVTWQCLIDGNSSDLEIVIVQEENPSVMCIKAQLEDQPHTLTLNAVVPTGDEFWFDQIQYTPSAGVSLENKTIFIESNDSEIKYGSGWVSTDGIGHATKETSSKFDFEFIGISLSWYSWNALDFSTDFATASYTIDGGSAKVLNVTAPIDVDRKTTIFNQKLFETPILEMGRHTLSLVYHGTENTIPLSLSYLIVQNGTIISNPSVGHNSKRNIGAIVGGVISGAVFIACLVFGLAFLRKRRRERQIRHHRRKYSNLDRDLKYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM08</accession>
    <name>A0A9P6JM08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_858926</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM08"/>
    <dbReference type="OrthoDB" id="251770at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="49"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="140"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="434"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="531"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="672"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="865"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="760"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="821"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="832"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="875"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1066" mass="115924" checksum="6E27077E2C60D528" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JME4</accession>
    <name>A0A9P6JME4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_909061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JME4"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="351"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="640" mass="70055" checksum="CE5900FDF5CACBC0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN21</accession>
    <name>A0A9P6JN21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN21"/>
    <dbReference type="OrthoDB" id="3065650at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="56" mass="6155" checksum="94EEC18E08E95A49" modified="2023-09-13" version="1">MYSKSGGKNGKHGDITKSSSISAVSFLAVQIFQPGLTRNFQMVTDTTSTLQTRHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNK5</accession>
    <name>A0A9P6JNK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_450831</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNK5"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9526760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="61219" checksum="E904FA77E21CDDDF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP10</accession>
    <name>A0A9P6JP10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_768874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP10"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="143"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23889" checksum="6CA7A1F10BE932EC" modified="2023-09-13" version="1">MLTLSAGSSCDVCFERFGRDLKAPCSIICGHVFCFDCVSHVNRLCPLCRTHFEPSSCIKLHLDVDTNPQSEQAPGSPSEDEREAQRLHQAINKVADTGIEEEALKQLIQEGKEFLNRQPRHMYKDVRNSLRIIAYTSELKHTLLGQRQMNEEINDEVQRLSTEKSELLKKLVEADEQRKYERETALAVETSLREHYALATRNYQVLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPI2</accession>
    <name>A0A9P6JPI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NRDE-2, necessary for RNA interference-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_895014</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPI2"/>
    <dbReference type="OrthoDB" id="297219at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902369">
        <property type="term" value="P:negative regulation of RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="199"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1131" mass="126646" checksum="AAB70749B96FC56C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPM3</accession>
    <name>A0A9P6JPM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_883775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPM3"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040282100" description="Protein YOP1" evidence="7">
        <location>
            <begin position="21"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="615"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="649" mass="71693" checksum="42F974F730C25EE1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPN9</accession>
    <name>A0A9P6JPN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPN9"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36511" checksum="837D9FD8C0394002" modified="2023-09-13" version="1">MTDWKAVDVQQDTLDVFVYVLHALTGVYIWEFLVTSDIECNVLFGRRTSRWPLIIYVLSRYCTLVSLILGVLMFDIGSPSLDCRATYIVVSVLSYISLGLASVNLAIRTIAIWTDNKYVTRSLCLIICVLWCLVIIQLATSFVTAARISGGRCLPGTKNKAWVLTTYVYSLFINSIITALTVWKLRERFGLPTAIYSQILFREGVGFYMIVFLFDLVAIVMLILNLNIAMSAIFVVSAQVAVTVVACRAVRSLCLKLRPPPEIVGGNWTQSFPIDLHTINTQQLTHSKTINSVPSRHQLESPSASQERSSKGRDLDLYMEPRHFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPR4</accession>
    <name>A0A9P6JPR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_766593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPR4"/>
    <dbReference type="OrthoDB" id="3043234at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="812" mass="91039" checksum="FF5614A41683E00E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQP8</accession>
    <name>A0A9P6JQP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">beta-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_853740</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQP8"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350868" description="beta-glucosidase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="13">
        <location>
            <begin position="813"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="62"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="893" mass="95029" checksum="8FF7FDED3C94BA9E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQW8</accession>
    <name>A0A9P6JQW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="15">2.7.7.1</ecNumber>
            <ecNumber evidence="15">2.7.7.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_905795</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>beta-nicotinamide D-ribonucleotide + ATP + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>nicotinate beta-D-ribonucleotide + ATP + H(+) = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the eukaryotic NMN adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="15"/>
    <dbReference type="EC" id="2.7.7.18" evidence="15"/>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQW8"/>
    <dbReference type="OrthoDB" id="422187at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09286">
        <property type="entry name" value="NMNAT_Eukarya"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000074">
        <property type="entry name" value="Nicotinamide-nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051182">
        <property type="entry name" value="Euk_NMN_adenylyltrnsfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045094">
        <property type="entry name" value="NMNAT_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00482">
        <property type="entry name" value="nicotinate (nicotinamide) nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039:SF0">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0520">NAD</keyword>
    <keyword evidence="9 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6 15" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="17">
        <location>
            <begin position="38"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9529666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="32766" checksum="A4A988901E85A59B" modified="2023-09-13" version="1">MPSKRLTESFTNPPDYAFPHHRLSRVLRNPEKTPVVLVACGSFSPVTYLHLRMFEMAKDYVRQNTDFEIMGGYLSPVSDMYKKPGLLSARHRVDMCTLATEETNTWLMVDAWEAFQAYQRTAIVLDHFDHQINTVLGGAQTEDGEHKNVRIMLLAGSDLIGTMSEPGVWAYTDLEHILGRYGCFIVERAGTGVEQATDSLARWRHNIHLISQLIQNDVSSTKVRLFLRRGLSVRYLLPNAVVDYIDQHGLYQDEITSSSPVIVTREKGADKDKESIPPPSSSTNGILQPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQZ9</accession>
    <name>A0A9P6JQZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQZ9"/>
    <dbReference type="OrthoDB" id="5599613at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="912" mass="99486" checksum="5350AFC8DD58A999" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRZ5</accession>
    <name>A0A9P6JRZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRZ5"/>
    <dbReference type="OrthoDB" id="3260094at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="72" mass="7987" checksum="4937FE6A73B8EA65" modified="2023-09-13" version="1">MKQYRKGGGGDVKTGTPNFWSVEVAAEQWLFDRISEDSPSVDNMPSMESISDAVSPPFQHTPLHDVEFLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS08</accession>
    <name>A0A9P6JS08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Linoleate diol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_810771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS08"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1086" mass="121241" checksum="BC5130C8BF723A15" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSA3</accession>
    <name>A0A9P6JSA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_905059</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="607"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="707"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1601"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2381"/>
            <end position="2456"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1601"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1723"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="1633"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2459" mass="267660" checksum="2CF73D2C3C69441D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSN2</accession>
    <name>A0A9P6JSN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSN2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="94" mass="10644" checksum="8EDA757486C01D53" modified="2023-09-13" version="1" fragment="single">RIVCGYPLIFTACTTPMSQSTHGSRTGAKDAYFWAPKVACSWREANHIGQVRVTLVRLVQTWDLSFFLTSYHHHAVFLPPSSPSFLQVPHKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSQ3</accession>
    <name>A0A9P6JSQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_847445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSQ3"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="30223" checksum="EF1F9D6ABA78300F" modified="2023-09-13" version="1">MNAMTDIPSQGSEGPEVIPVTAMFNPQIMMAGSALVALLLISFIFLLTRRRTSSKGTALLLVGPPDAGKTSVMSQTAFGQPWQTQTSMQINMSAVTLSPKKMFPVIDIPGHPRLRGQFTEHLPSSKAVAFVVDSSTISRNAAAVAEHLHLVLHALTSLPPSQHQPALLILAHKSDLLKATASSQNTHTLAINRVKTILERELEKRRASQSGGINIEGLGDEGESTELGGLQCGEKEGASFKFDEWEGGEIIFLGTSVLQNGSAKEGSSNGLESLQQWLQDNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTD3</accession>
    <name>A0A9P6JTD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_807418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTD3"/>
    <dbReference type="OrthoDB" id="3202436at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="2">
        <location>
            <begin position="255"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="43354" checksum="BA5350DBAD9CD092" modified="2023-09-13" version="1">MSIPTSPAYSEPREVWDIHAGFYRPIGSDLSQTWQPSPEVTNPPLPLLSPLKPVFELPRHTSLPSGSGSTTSHTLAIDVPTAYPKEKLGLWARIRRFIKSGPNSSVVTEKVKVPVYQPSPSPFPSAENRVNPNEWKAYGYWALPLINGVECPNSPFISEESISSPDLEQMITSLRDSNGRQHKDKWKPGVRHPALPPRPARWKRPQVGQPLPFPWEVQVNPMLQHHIWGPAPLSWCLCAKPQNMVFHGRATNGVPVNNADFAQPATYPFLTHMHFNAVAGDSAPAFPWPFTVVNERGIKVRDVLEEIWRIFQARVAEEEHLSWPPLRREMAAWALEKRCQVLSEPGRPYRDFLRRCDSFGGIMFFRGIEPTADGCGWMISFGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTE2</accession>
    <name>A0A9P6JTE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTE2"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="163" mass="17901" checksum="A806F1B53ACF9BBA" modified="2023-09-13" version="1">MAEDDVVAQEAKVGYRSVRGAAFATLGTRDFSIWDIYSFLAHRNQATSKIGPGIDGWYISRRVDLNQSNSLPFIASPLLLMPPYPPLSSVSVLATTDWDQYIVVDLKVPENLSPQYSIHLTEIGTYSLGGALSDRRLFALCLDRGNPTGSLSFYISPSPDQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTF4</accession>
    <name>A0A9P6JTF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_847625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTF4"/>
    <dbReference type="OrthoDB" id="2563136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="79" mass="9014" checksum="1A27B0CA47DCC4F7" modified="2023-09-13" version="1">MSSGKTAQDQTWKSREQAEEANYVRQKEREQLEALNSKLDQKDTSKAKTEVKTIDRDFEGGFGGQEDLEDRYATTSGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTF8</accession>
    <name>A0A9P6JTF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_783508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTF8"/>
    <dbReference type="OrthoDB" id="3219854at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="31"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="676" mass="76486" checksum="6653C7A859FDBE17" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTJ1</accession>
    <name>A0A9P6JTJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_49553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTJ1"/>
    <dbReference type="OrthoDB" id="414418at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF51">
        <property type="entry name" value="TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="30105" checksum="BDE51954DF9F25A4" modified="2023-09-13" version="1">MPDKIYIARHGFRLNWITTVWKSPTGLPRDPPLAAYGEAQAEELAKHFLSLPEDQRPTAIFSSPYYRCIQTAQPTSQHLNIPLYIEHGLSEWYSPVAPSTGLHPRPSSAQSLTTYFPSINTTWSPVYYPTRKGETIEELHDRIDEFLQGFYVALIERLPEEQRKRPLFVSHAATVIALARSLVGDRELPLKVGCATLSEFVPKEGAWKALELASGKHLAKGADREWGFEYVEVDKGRVVEDPGEGENGEKDEPLGLQIKINPPGLSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUF9</accession>
    <name>A0A9P6JUF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUF9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="26853" checksum="0F4A2720188BFF1D" modified="2023-09-13" version="1">MDAGQVDSFNSSSQIDAYLLDFHPHPSTSRPRRKSRAAYPGITGHSWLRRPCWETSFANDSSSSESEDSDEDDYSWYYKNPDRYVWRPRKNRVNRKVGQRPAKLDLDLSNTEPLASKKYSLPSPTAPSPLLSPGSKLLWRDDFGFPELFEGSQKARLQPMPTSPYTSNPPSSRSSSEGRALSWVNTPTSSMESFDITSEERRTSCDSSTRIRRRGHAAWLESWHSSPFFTSEPSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUG6</accession>
    <name>A0A9P6JUG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_938882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUG6"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="68"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="147"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="192" mass="21889" checksum="EB48D94CB90B45CD" modified="2023-09-13" version="1">MQIFVKTLTGKTTPSTLNRRTTVTAYTRIQDKAGIPHDEQLEDGRTLSDYKIQKESSHPLVLDFRGGMQIFVKTTASDWISSFTRSIHVDRSYTKIQDKVGIPHDEEHLIFTGRQLEDGRTLSDYKIQKESTRRLVLDFRGGMQIFVKTLTGKTTPSTSNHKAGTPHDEQRLIFAGKPFEDGRTLSDYNIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVG9</accession>
    <name>A0A9P6JVG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_9386</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVG9"/>
    <dbReference type="OrthoDB" id="1913277at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039205">
        <property type="entry name" value="NDUFA11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="16283" checksum="65194918D680D083" modified="2023-09-13" version="1">MADSEVQTSAYEAKSPVANASNVALKAGAVGFFVSSLQNALGKHGYGAMGILTRTGGTVGFFAAMGGVFAYTEAYVANQRQQDDHLNGAAGGCAAGFLAGIKKRSLPLAVGSCAVLGAVIGAYDFTGSIAGDQTSTAERRKRFFKNPPKPLVETEQAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVS3</accession>
    <name>A0A9P6JVS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVS3"/>
    <dbReference type="OrthoDB" id="2874598at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="22896" checksum="63B2856BCFE775B7" modified="2023-09-13" version="1">MFRKRPDGEKQAAAHSGNSNRRRIAWDIPIFFGIIFALSIAELCFTIDAFIYLNKLHKWYSKTEKGRMGFLIFSCVRTIFLSGTYAAAHFFYVKNLMNTLHLIFLIMSAIFWVISGVLIYQMWSYMECNNAGIPTSFGQFKSLVSGGISLCHEIKTIEILAWVIAAVSVIATIPVIMTYMKMKRQKRARVDGINNEKNGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW10</accession>
    <name>A0A9P6JW10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Carbohydrate esterase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_844974</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW10"/>
    <dbReference type="OrthoDB" id="2125469at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040139533" evidence="12">
        <location>
            <begin position="18"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="13">
        <location>
            <begin position="39"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9534020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="27748" checksum="931C1AAE7C99D49D" modified="2023-09-13" version="1">MFAPLAFVTMAMALVSATEPSRLQKRQNAQVVTNCVKPNTVALTFDDGPWIYLQDISNTLKAANATGTFFFNGNNWGCIYDQDMSARVQYAYKNGHQIASHTWSHADLTTLSWDNIHNEMWLVEQALTRIAGVTPAFMRPPYGNYNDLVLQASYIRKQVVTIWDFDDGDSTGASAAQSESDYDALVRSHPGTVLSLNHETQETTAHQVLPYAIQKLKAAGYQLVSLADCTGLPAYQFVGSPQTRTSDWHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWQ0</accession>
    <name>A0A9P6JWQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polyadenylate-binding protein</fullName>
            <shortName evidence="10">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_841528</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWQ0"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000441">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000648">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="44"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="132"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="225"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="328"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="13">
        <location>
            <begin position="591"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="448"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="528"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="544"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="572"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9535293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="673" mass="72803" checksum="078A067AD64BB79A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2I9</accession>
    <name>A0A9P6E2I9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_778843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158094">
        <property type="protein sequence ID" value="KAF9521379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2I9"/>
    <dbReference type="OrthoDB" id="3143151at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33104:SF2">
        <property type="entry name" value="CXC3 LIKE CYSTEINE CLUSTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33104">
        <property type="entry name" value="SI:DKEY-29D5.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="1">
        <location>
            <begin position="164"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="903" mass="102606" checksum="29473EF4831E2C3C" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2J5</accession>
    <name>A0A9P6E2J5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158064">
        <property type="protein sequence ID" value="KAF9521439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2J5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="168" mass="18930" checksum="60DBAE664164EB57" modified="2023-09-13" version="1">MANSNAFDKRRPSLLCLRRLGDGFVERARPLGCEIWWIVQQLAWSVCSVAESDDSVMRSLSVRFFRYVVPSALSLDKLVLQLLFNLFLSLTLLSSSSTLLYIIYRFRLTRKRTPGLIHVPISNSSTQTSSTSASATGFYIIKAKWDVKPPSSVSFNTLRLIAHLRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4F4</accession>
    <name>A0A9P6E4F4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4F4"/>
    <dbReference type="OrthoDB" id="3011453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040135139" description="RxLR effector protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20573" checksum="F41DD51C8E87B0C8" modified="2023-09-13" version="1">MVKVASTLFFTALIAAPAFAAVINAEHLQGREVTDQALFGRDLSETEATEYVRELGDLYTRMPEEDTDLLVRDLETDLEARSPNKAKNFFKKLWGGIKKVGSIFLRENEAEQLDEVAAREFDDEVEARDFDEPEFEARDFEDEEEMAAREYDDDLLERDFEIDEDLMERDVSDLEELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4T9</accession>
    <name>A0A9P6E4T9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_864229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4T9"/>
    <dbReference type="OrthoDB" id="4838853at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="332" mass="38050" checksum="C0555F266DB51650" modified="2023-09-13" version="1">MADSETKQPQRREVDKDSLASQPQIQTPFATSEKQDATTLELAPSSPRSSISQPPEEFPELYFTYKWSNICLYALFLFFCNFIFPCILFYPLETLTSLTDHTVVGISSAALGLSSCFDSPLRLWRLIKFRRIYGPFEDDVWWHLDFSMWAYTIALFIFAVPLAIAPGLKLFDFFLMSTVLLVGPVGVIFLFSTFGLKVPFRCSSDPAGSQMKPAVFYLIEDVASVDFQHGRDFRRTLYRRYHASPPFRRLMMNLTIYWVISSAVYCGATAAVTWTTPFRFAFGYTLGQLFIWGALSAVGCKLLARKGLRDERKWLQSRKEFAMKERSQETIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E553</accession>
    <name>A0A9P6E553_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_911213</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E553"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="4">
        <location>
            <begin position="481"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="604" mass="67597" checksum="A2318B03A037DC78" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5J5</accession>
    <name>A0A9P6E5J5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_70692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5J5"/>
    <dbReference type="OrthoDB" id="2822637at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="11170" checksum="10B9FEC190296615" modified="2023-09-13" version="1">MIKVLTLQSKQPSRHIFSSLKPSYIMLFFKIFAPFFIVGLSSILVTANPLQMDKRDCCDPNSFFPCNGACQLTCIDPELGGVDQACSADCANDCCPEGVVCPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Q2</accession>
    <name>A0A9P6E5Q2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mago nashi domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_871802</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mago nashi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Q2"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11295">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1560.10:FF:000001">
        <property type="entry name" value="Protein mago nashi homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1560.10">
        <property type="entry name" value="Mago nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004023">
        <property type="entry name" value="Mago_nashi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036605">
        <property type="entry name" value="Mago_nashi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638:SF0">
        <property type="entry name" value="MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638">
        <property type="entry name" value="PROTEIN MAGO NASHI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02792">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89817">
        <property type="entry name" value="Mago nashi protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="147" mass="17091" checksum="868FEDCD27B0A775" modified="2023-09-13" version="1">MSSLENDPFYLSTGHSGKHGHEFLEFEYSHGRLRYANNSNYRNDSLIRKEMWIGPLVVKELKRIVEASEITKEDDSNWPKKNIVGKQELEIRVGSDHISFETAKIGSLVDVQDSEDPEGLRIFYYLVQDLRCFIFSLISLHFKIKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5T2</accession>
    <name>A0A9P6E5T2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5T2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="195" mass="22077" checksum="E9A7CF5450F62CEA" modified="2023-09-13" version="1">MSTQPPLIRSSYFETPSSLYYHFIDTLRPSPFVQPITSFSLLLHPPPFTLHPSHSHSRSHSYQYQYVTLHLIPTPTHTPTPTRIPLHSKLSLLPLESLSPNPNSHSRPLPFIPHQHHTNPPPPINTDLPPQSTPTHILKAFLSTLDHPPSVTSYLHLPSPMHSYRILHTPPSLYIPSIRTPIDSCALPLLNDRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E668</accession>
    <name>A0A9P6E668_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_863159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E668"/>
    <dbReference type="OrthoDB" id="346673at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="6">
        <location>
            <begin position="96"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="7">
        <location>
            <begin position="350"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="422" mass="47159" checksum="5C214A672BC24E88" modified="2023-09-13" version="1">MKKTTTMNLRILLEKRRTMGTWRKKILVEGQSSNIIVQTAFDAYFTYNKPGRVQTSSNIFSDLLIPLSSEEYHQAFDQIKITQLSIQPSLLKADNLHSFFSRMTCELDEGFNILCYGLGSKRRLLNQFAREWCSKRGHVVVANGFQPDFSLKDLLNSIEDVPALQALDLPSTNIEKQARRIYDFFVSSKVHLYLVIHNLDSAPLRAQKSKSILSLLAHHRKIHITASIDHINAPLIWSSSEIFSRKPEVIEPGTTPSRGFTWLWHDLTTLQPYDFELAFADRSSLSGAHTGGARRKVDALAAQNVTAMSETAASHILASVTQKAQKLFVLVGNKQLEAIEGSDEGLGVGNLQQFGMGYDVLFSTARDNFIATNDTALRALLGEFRDHSLIVSAQAGAGSGEVLWIPMRKERLANVLRTLDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6A5</accession>
    <name>A0A9P6E6A5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_693934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6A5"/>
    <dbReference type="OrthoDB" id="3049838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="59495" checksum="BF727D9EAC369BAD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6G8</accession>
    <name>A0A9P6E6G8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_887023</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6G8"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="494" mass="55447" checksum="4069450356F61461" modified="2023-09-13" version="1">MSYLNTSLALIFGIGLFFFITRSLSRKKLPPGPRGLPLIGNAHQVPTETPWISFRQWSKHYGDIIYIDLAGQPTLIINSRKIASDLMDKRSSIYSDRPSTEMIKLCGSDSIITLQQYGDDWKKQRRMVAPNFAQSYVPNYYELQEKQTAYLVRNVLQDPATLASKIKLTTYGYSVGSKEDVFLKNGLVAIDNFSVITTPGAFLVDLIPILASSIHLLYLRTQSMPVKFLPRWMPGSDFLTYAEECKRQLLQTCYDPYLWWKENHNAGRALQPNMISNITLKAEGKLTTEDEKQALWASLTMLGGGLDTAQAEIDIVIGKDRLPSINDRPDLPYVRSVIAESLRWAPALPLCVPHVLSQEDIYNGYSLPKGTMVMANIWAMFHDPENYPDPMTFKPERFEGDDVEMEKISIVFGFGRRICPGRYFAEGTLFSAITTFLATCDILPGLDGAGREVMPEAKYSSGIISIPEEFPIRVKARSSRAAALLAEATSTAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7E6</accession>
    <name>A0A9P6E7E6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_644988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7E6"/>
    <dbReference type="OrthoDB" id="4764735at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="26349" checksum="C7C351495B19806C" modified="2023-09-13" version="1">MVVFSFVPTAKRGFFVSSFSSRSSTCLPPLLDATIKNTNEAGEDICYVSVGLDGSYFLGTQKRNNHYGYTNFPPLLTLFEAASASSPGTFSSDSVRWISFTPDHKGYFMCFVLADQKPLYAWACLPESLNKILEGNAIEDNDVLNFVSFGKDGSWVLTIEGKKPMWDGVPKDLEERLRGSDTIATVALALDAEDEYFMEYEDGGIWMIIPKEWHRTVKPHLDDKGAIEQINVCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7V4</accession>
    <name>A0A9P6E7V4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lectin PVL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_798628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7V4"/>
    <dbReference type="OrthoDB" id="3153136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44103">
        <property type="entry name" value="PROPROTEIN CONVERTASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44103:SF1">
        <property type="entry name" value="PROPROTEIN CONVERTASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="438" mass="46781" checksum="179484B2322F0953" modified="2023-09-13" version="1">MSIASGGPLPQQDGAYFGPSLSVDIVPNQPIVISQDHPIPTTSPGKADIVGFGMNGVVVLRDMLSIHLRSLDTYGEFGYNRAGWRIDKHVRLLADVTGNGKADIVGFGEEGVWVSHNNGDNTFSMPPKKVLGGFGYSTATGEWRVEKHIRCLADIRNVGRCDIIGFGEKGILVSKNNGDGTFTTPNLALIGFGWDQGWRLDKHLRFLADTTGDGLLDIVGFGETQVYLSLNNGDGTFGPMKSVFATLCHGAGGWRVDSHPRFLADLTGNGLVDIVGCGDQGTYVALNNGNGGFEPSSGRLVVNMFGTAQGWRVEKHPRFVADLTGDKRADIIGFGEAGVYVCFNNGDGTFQPPKLILSDFTVQQGWLVAKHPRFVVDLTGNGCADIVGFGNDAVWASFNDGKGGFGPKTKVIDGFGFNGGEWSLDTTLRYPVNLGTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7Z9</accession>
    <name>A0A9P6E7Z9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_621767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7Z9"/>
    <dbReference type="OrthoDB" id="3254160at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="961"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1155" mass="127376" checksum="6435D8E3BACB242A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E857</accession>
    <name>A0A9P6E857_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_638325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E857"/>
    <dbReference type="OrthoDB" id="3017464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="9546" checksum="8802A3B626C21BDB" modified="2023-09-13" version="1">MKRLGFFFNKDTGSQSMRAGGATNLAEHGVPPSIIQASGRWSSENHQCYYLVFYLTAHTHTYTKAEVDIHFTARAVNASQSTSFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8F7</accession>
    <name>A0A9P6E8F7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pyranose dehydrogenase (acceptor)</fullName>
            <ecNumber evidence="5">1.1.99.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_610154</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O(2) as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a pyranoside + acceptor = a pyranosid-3,4-diulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a pyranoside + acceptor = a pyranosid-3-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>pyranose + acceptor = pyranos-2,3-diulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>pyranose + acceptor = pyranos-2-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>pyranose + acceptor = pyranos-3-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.29" evidence="5"/>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8F7"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033718">
        <property type="term" value="F:pyranose dehydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF218">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="19" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040299282" description="pyranose dehydrogenase (acceptor)" evidence="19">
        <location>
            <begin position="17"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="20">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="637"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="643"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="570"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="613"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9524382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="687" mass="71906" checksum="F0D6DB287622E550" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E968</accession>
    <name>A0A9P6E968_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High mobility group box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_773275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E968"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="10310" checksum="8CE14A7AC05E65E4" modified="2023-09-13" version="1" fragment="single">MPYVPDPKKKSHARKQPEGHIPRARNPFMLFRCNFVDQRLVPSFEETDHRNISRIAGRIWQDMMEEEKVPWVEMAAAEKLEHMKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9L0</accession>
    <name>A0A9P6E9L0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_570247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9L0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="382" mass="42657" checksum="0D018E2EC585B0C5" modified="2023-09-13" version="1">MDLFTETNRIPQSPTLCIRTTKGISTVGGISVLSTTPITPLRTPKSTTRRLLARLRNFRDEDDEQRGRQTEVARSRRRGNSVKGKSRSDGSTLPSRIPTFASAVKSSILSNTPDPTPRSLQVTRPSPIHSVSDLVFDPFYHTKLVLGMPGEVHTSKRPGPLARAPTLEGVDEVDEREEEPPVPMDDDFDADEDLEANTLLWYPPPPIMLPPPIPEAPAYHHYEDDFPMHDDRNINQATTPSFNGQFRSLDVDMDDDGFGDHQYDSDGSEGSSMDAQIDVVEEDSDDEEFDDAAMSTSRFLHRTAYESILTSTVHQYLGYMEDGGRVTLDDPMDYSEDGLGMAGRSIRRRRVRRSITYPRRFSSLMGVSLAIMKDKIGVSTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Y2</accession>
    <name>A0A9P6E9Y2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_909085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Y2"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="420"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="61097" checksum="53F3B07C2764A100" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAF6</accession>
    <name>A0A9P6EAF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAF6"/>
    <dbReference type="OrthoDB" id="2100128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398:SF1">
        <property type="entry name" value="CSN8_PSMD8_EIF3K DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398">
        <property type="entry name" value="YALI0F14311P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="412" mass="46199" checksum="994314ED28CF11C5" modified="2023-09-13" version="1">MPDWRGRGRGRVYGSSTDQPWRGQGRGRAQSGPSGSRGATSPLSTPSERTVLRSVRGMPQTRGLLTADPDALASQRRMNLMASVSRSSGLEKDGDDHGVVIELQLRICSLKHHSTQEEYRKFIQEKEDHALRTFQNSSSETEKERKTRIETQENVLILFRKLREGVASSNRDDSFAYEVYETSLYLSVLFDSPKQTISIIPHLSSRTPDLRPICQSVYSLLGSILHYLVVYYPSQGQYFQYLQSIPSSTLSRSPQSEPHTWLSALSRSLRARNYAKLSLLTSKATILDVIQKAPSNGTGLIQPDQSNHGLPHHQADSKLGQDAVLHLLQALRQKSAVTTWSVLRSAYREISTADTAEGKSTSKWLQKSLLLEAVTSKAQDEKAESWLLSKIDLGYVRKKEDVEGRWIVCKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB28</accession>
    <name>A0A9P6EB28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB28"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="9631" checksum="509F52D0AF596D39" modified="2023-09-13" version="1">MDKPPLVCTLTTLSYTTTVLHPHLLQLNNRRQLDIRNLVRRACAPEFPYKFKDALDTLLICFCEESTNNPTRALKQFHNIFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB86</accession>
    <name>A0A9P6EB86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB86"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="424" mass="47999" checksum="B5F3301B08FC2C4B" modified="2023-09-13" version="1">MNQIPVELHALIIGILVSEGFKLSDYALTCSAILHLCRAHIFAQIAFEFSSKTYDDQHRHVQFLQILTKSPEVANMIRHIRLKITRSRFRGEEEALLKALCLSVGSIEELGLISFNLKWGDLLEMAELGLLIRTCLASCSLRSLNIGNFIQDFRMSDVRDCTQLSKLVLGLHRTLIFDDKDKNPSLICFPKNLRHLFIYHTKRRDDLVAYRLAPNPIPESQLFPLQSFHTSTSSIELIGIILSQVKGLEELTLRWELSSEERPFAQLGESLHLQLGSLRSVTFVFPYDTVRFGAIRNLADLLASMSKSLNGNSVRKITIIICINRAFNVELLSQACRQVDATLSSSNNWPSLEKVSFETLLIAGRSDGERAAVNLQALRNRFPQLLGSGVLRFRYDQIDNKGFGTLPDNIHPLLKELFEVRYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB91</accession>
    <name>A0A9P6EB91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pregnancy-associated plasma protein-A-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_771306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB91"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="9">
        <location>
            <begin position="118"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="27012" checksum="C3AA7E79082E2CE1" modified="2023-09-13" version="1">MIKELREKSPITKRQDGQQYNFGVYFNIVASNLTEAGGYVPQKQIDDQMTLLNTKYVGTGISFKLLSVTRVVSRYWHETIDSGFYRPQTDAMYSLFHKGSSTTMNVYSVGFYDAGLNGYSTLPASYKSSPKRDGVVLLYATLPGGTSKDRQGGTLVHEAGHWLGLRHTFQGGCTGAGDGVDDTPPSAEANFDCPIGLDSCPGDNFPDPIHNYMDYTDETCRTEFTPGQIDLMHKSVATWRSDPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBU8</accession>
    <name>A0A9P6EBU8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Alpha-amylase</fullName>
            <ecNumber evidence="4 12">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_940153</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4 12"/>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBU8"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11317">
        <property type="entry name" value="AmyAc_bac_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05808">
        <property type="entry name" value="CBM20_alpha_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000552">
        <property type="entry name" value="Related to glucoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 12 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040346673" description="Alpha-amylase" evidence="13">
        <location>
            <begin position="21"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="14">
        <location>
            <begin position="469"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9526236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="569" mass="61107" checksum="B4560D3EA98CE12C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC86</accession>
    <name>A0A9P6EC86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC86"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="10975" checksum="192A3B85FCA2468B" modified="2023-09-13" version="1">MFNPTLLKDAISPVNKPVEGELNAKADQAVNQPVDPTTLTVGPDLETMPFCPLSPIPKECPKPTVKPSVYIIRLQNGKDTTHVLERQLARLLVQKYLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECI5</accession>
    <name>A0A9P6ECI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSm2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_870323</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECI5"/>
    <dbReference type="OrthoDB" id="10256176at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01725">
        <property type="entry name" value="LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000009">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016654">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829">
        <property type="entry name" value="SNRNP CORE PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829:SF2">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016394">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="96" mass="10984" checksum="23304DD0954FCF9E" modified="2023-09-13" version="1">MLIFSVFKTLTDQTVTVELKNDLSITGVLKSVDQFLNIRLDNIKVADEGRHPHMMAVKNCFIRGSVVRYVQLPAEHVDTQLLEDATRRDAMNQVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED26</accession>
    <name>A0A9P6ED26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857412</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED26"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6857" checksum="746C7B0E9E9836CC" modified="2023-09-13" version="1" fragment="single">AISRRHQAQYFHLPHSIPSTQPSFFLQVVLLQKDTPIRIRQKKLRVDNHTITSFLSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED40</accession>
    <name>A0A9P6ED40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Beta-galactosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_794210</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 8"/>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED40"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000065">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000088">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040430287" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="11">
        <location>
            <begin position="386"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9526882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="997" mass="108155" checksum="D8976855397008E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDJ9</accession>
    <name>A0A9P6EDJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDJ9"/>
    <dbReference type="OrthoDB" id="10262962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF195">
        <property type="entry name" value="ACID PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040514707" evidence="2">
        <location>
            <begin position="16"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="472" mass="52225" checksum="A0949F9E378BC5CB" modified="2023-09-13" version="1">MTLGASMFFASVGLAISPVHYPPSSTKINDLEFALSGSGAPGVYSSSYTPESQYGVYNWCNMPHVRPKEYRTPPRNYSLEYVEVIQRHHKRTPYASNTFNQEDIDWFCTGSGPTFGATSSKGEGTNGSPVQWQGFVDSNNPWTTTVPPGFKNSDCQFPQITDQGLEDAILHGKDLRGVYAPLLDLPLHIDSDIAAIRVTTNVITSQVASGLAKGLFPASLSENVPVKIQSANFDSLEPKYSCNRASTIRSDITTGSQGDLWKNHLNKAASIFEKLDKVSGFPKDDTGGWHVSFDHYYDNLSAKQCHQKRLPCNLHDSSVCVSQEDANTVYRLGNWEYSYLYRDAQASAEYAALRYGAWVLELRGHLQAKMDGNSKLKYLHNVAHDGSISSLLGFLQIDQMVWPGMGSEVVFELYSSKSAHSSSWFIRVLWSGQPIKTSTPLGTLDMVPLEQFFQYIDSMVGSGNDLFAACYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE00</accession>
    <name>A0A9P6EE00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE00"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="54" mass="5781" checksum="D16BD5C60D09A1C6" modified="2023-09-13" version="1">MSIFKEPDPDTYLSSAQRCQRTTRSNKACIASGSAALCQLVVIGACQVSILLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE27</accession>
    <name>A0A9P6EE27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE27"/>
    <dbReference type="OrthoDB" id="3220849at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7863" checksum="1E657959BAB22D85" modified="2023-09-13" version="1">MASDSPSPNHVRKQVACPPSPTMSPSQAIAEAWKRESMENQEKWRRVDADVKVRYNTPVRLPRRKTKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEI6</accession>
    <name>A0A9P6EEI6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_391763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEI6"/>
    <dbReference type="OrthoDB" id="3221235at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="688" mass="78677" checksum="8A783FC981AE73AF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGD2</accession>
    <name>A0A9P6EGD2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_314194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGD2"/>
    <dbReference type="OrthoDB" id="10251048at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF4">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="370" mass="41147" checksum="9C372F1EC207FBB5" modified="2023-09-13" version="1">MQRLNIQRILQRRGIGHVSKSTAGLCHFHATSKPPPLSFVFDIDGVLIRGPHVLPTAKRALKYLEGDNPFQKKIPYILLTNGGGIGEHERCDKLGAKLGFPIKPTQFCQAHTILKKFAPKYADKPVLVLGGERDVVKKVARSYGYQKALTTLDVLAWNPSVWPFHRLSEAERAVTESIDFSKTPIAAVFVYHDPRNWALDVQVTCDVLQSGGVIGGPYISSRGRTPPVELVFCNPDLIWRSDFDRPRIGQGAFKVAFQSVYRALTGSEYPHVQYGKPTQATYEFAEELLNLHLHDLYGAPNQFKPYMVGDNPESDIAGANAAKWSSLLVKTGVYEPANGPPAYKPTMIVEDVEEAVRWAVEQELAKTKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGY2</accession>
    <name>A0A9P6EGY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal protein S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_789948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGY2"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="14341" checksum="62674ED4022C032D" modified="2023-09-13" version="1">MPLYEMLCITTHVSTYSHIRELVRQSASHVMHQGGVVRAINSWGTKTLPQRMKRHGPLQNVADYWTLHFDASPRTLRSLNGIMRRDPRVIRWTVLKLADKVEDLADRGEKLDMARNPIPENIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH21</accession>
    <name>A0A9P6EH21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_853720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH21"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF30">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="7"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="25557" checksum="71A15844C54653B6" modified="2023-09-13" version="1">MPSFTDDSETQQAKLIINAAKSAGATHIVHSTNISIPRPEEGKNWDPKSVAAPALEGKQVVEEMVRRAGFTSWTILRPGVFMTNFFTPFVGMMFPDLLTKGLFVSSYRPDTILPLIDPDTIGAFASSAFLDPSKYGGKEIRLTGDPVKVEAIVEAMAKASGKKITASYRSAEESQALAETNPFIAGQLFSLDLYKYIDMAEVRKWEVKLATFQDFLDREHVLVAKTFERVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHD4</accession>
    <name>A0A9P6EHD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_247158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHD4"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="330"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="605" mass="69137" checksum="5540B9C1FE81FC95" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHG6</accession>
    <name>A0A9P6EHG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_298825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHG6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040515127" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="9611" checksum="8F427B4E09303DC5" modified="2023-09-13" version="1">MRFSAVFAILAVSAGSVIAQDSSAAASSAAASVASSAAAAVSSSAAGVISSAASGVSSAASSASSVSKAASSSAAAPAATKTNGASPNGVQSLAAFMAIPAAVGLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHR4</accession>
    <name>A0A9P6EHR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_240747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHR4"/>
    <dbReference type="OrthoDB" id="10646751at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="218" mass="23515" checksum="55988963369B283C" modified="2023-09-13" version="1">MASTTTLLQDILPGPGFPQSINITRTTAIHADEAAAKLLASCEGSPAIGIAYHISKRGKVDFVCLATCSSACLIKFSKPGQISTKGMFASLLASNGKHGQLSEKSNATTHQTILVGFQMARIAVQVNHVTKQAVRGVDLTRLFTSDARDSPADIIHKRLFSAVDSWKVAQLWIGEDDSVSRDLPLQAWLAACIGLRHKDKLASSHLINTDHLHFLVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHW8</accession>
    <name>A0A9P6EHW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHW8"/>
    <dbReference type="OrthoDB" id="2799068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="39"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="37674" checksum="E715E30E81CB3247" modified="2023-09-13" version="1">MAPPTKRPRVETDEEMSDDSSDSEESLPEHSSKFWLEDGNIVLQVEQTLFRVHGSMLARHSEVFKDMFSIPQPSKPQGAMVENCPVIHLSDAAEDVEEILSIFYDNMKAVDRREIPASMAIAMFRLGKKYQIDYLSEEALEAFRKDYPTDLKFWDPVSDTIITGARVALIKLAHELSLRTVLPALYLDFVSMNGLSDIFERLDTDILKTVVTGRDRLILHLQQEKCRYIIQIIQNKPAIFCCDSAECKSRRVNAFEELSLWRLWDGNMPHDLRVWTEAGTKLPRQVCSSCKKQIRIIFDKVREDTWEKLPGFFNLGRWEDLEDDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIH9</accession>
    <name>A0A9P6EIH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3364707at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1496"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1614"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1099"/>
        </location>
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        <location>
            <begin position="1100"/>
            <end position="1109"/>
        </location>
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        <location>
            <begin position="1110"/>
            <end position="1146"/>
        </location>
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        <location>
            <begin position="1175"/>
            <end position="1193"/>
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            <end position="1204"/>
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        <location>
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            <end position="1233"/>
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        <location>
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            <end position="1348"/>
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            <end position="1404"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="1453"/>
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            <begin position="1501"/>
            <end position="1515"/>
        </location>
    </feature>
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            <end position="1576"/>
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        <location>
            <begin position="1629"/>
            <end position="1638"/>
        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1749" mass="185640" checksum="9926B76B736D8354" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIL0</accession>
    <name>A0A9P6EIL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_249466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIL0"/>
    <dbReference type="OrthoDB" id="2921613at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="479" mass="51914" checksum="E345DCE78A43C5B5" modified="2023-09-13" version="1">MDLSTNSNQGASANGAASPSASDMVSEGSVEDDIPPSRPSSRLAFNRSTVAGDTTANALAVHSVSYNGLSQPSNSPVKGPGDTKALSSPSSPTLLARTALGDCTKCPTSTFVDQKCLNGAPPKGIPSADGSANTPSSAPRKSATSVSRLCFPYVKTSPRSKKASAPAPPRHKHSCFPTKFAPYEATRPATAHERHNYRHHGHSRLGLEHIKWLWSLREDELKGDSAENGEKAYAGILPEPVGGVHPTTHPGSHRSHDQVTHGAPAPMSIHPRRGDVSALRDPYCVEIDRSFITLPTWTIAKTLWMHDLHLAFEKRRPRLKIVLDDDVSDVESELEMETSRSTSYSSISEDSDATLFDSETEFEWYDSDRLSLKMRNISSTSSPSFASSPAVSPVPPSSDFIIKASWLSAPVVAEALTHHSSLAFKPAWTTNWYQRWEVLKGHAQRSWNRKDKSFGSIAQLGPSSNDNIWSPVNAAPVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIN2</accession>
    <name>A0A9P6EIN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_259550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="69"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="309"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="641"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
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            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="266"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="518"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="645"/>
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        </location>
    </feature>
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        <location>
            <begin position="677"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="727" mass="74351" checksum="0839DA644AB619D0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIV0</accession>
    <name>A0A9P6EIV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MFS monosaccharide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_892762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIV0"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF17">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="27"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="535" mass="58141" checksum="D8F4A9454BEA98B6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIX5</accession>
    <name>A0A9P6EIX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_882572</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIX5"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9529920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="240" mass="27085" checksum="77EA4647220B466C" modified="2023-09-13" version="1">MQEMIKLSFEATKKIILTVKKWFRRLLGRCMLSAVVLASCVLGLLTHPDVIKTAQEDLDVVRAGKFPVYEDEASLPFITAIVKEIMRWRVITPLGIQHNFPVDDGYLISHDSIIFANSSYEAKLTPLPRWAMLHDQTVYSEPSKFKPEHFMKTENWIWIPVIQLMLYGVLVDGWHAPLAPVKIPTNRSAGICPGRFIAFPAVWTAIASLLYVFDIEKQVDAVGSAIEPSIEDTVGVLKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ18</accession>
    <name>A0A9P6EJ18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pre-mRNA-splicing factor Cwf15/Cwc15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_789568</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ18"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="253" mass="28413" checksum="511CE4746A8BD902" modified="2023-09-13" version="1">MSTAHRPTWDPAQARDVKGGSRQFSVRDMAAHTKLKFRQVGQTSTAEVKKLDLRAELLAAEHEARNKKRKAEGLPPLEDPSLAGSSTPAALPPPDEEANKRRKLLQEAMEMDKDDDDEEEDEKDKKMSDDESEEESDEEDEDDTDELLRELEKIKRERAEEKARLESEEAAGAAASREAEIATANPLLNLAAALGQSPGVNTTVPGTFQVKKRWDDDLIFKNQAIDQKQGQGNFVNDLLRTEFHKKFMAKFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJH3</accession>
    <name>A0A9P6EJH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJH3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="22121" checksum="A133C604EE6B81DE" modified="2023-09-13" version="1">MSQSSVKISFSNVTFNGSSSINIFDGNGFRSHELNPRLNRQGSPGANTRSRPKDGADRNAKASTNEKATENEPEGASDGVSNTSSSSSSSKEMVTFIRPHPPQTYSPATMQDKSKDTSEEKPEEVQDGQDRPSATFTSTQRRTVIQGPFRVTAEASITGMSAEHLKQMEDMIETVDQRTSAVAEAARQKSTRKHRYRCEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJI7</accession>
    <name>A0A9P6EJI7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_809745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJI7"/>
    <dbReference type="OrthoDB" id="10262413at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="11"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="37289" checksum="4D13F00887AAE357" modified="2023-09-13" version="1">MSSKTKVLFTGATGYIGGTVLKHFLNYTEFSSYEITALIRSSEKAANLEKLGIRATVGSYNDATFTESLSAEADIVISAADADNVPAIRAILAGLKKRHTATGILPVIIHTSGTGVVGDNAAGDRASDFVYDDTKVEELDALSDTAIHRPVDLTLINADKEGYVKSYIILPSAVYGSASGILLDKGIQKPHSSDLIAYLGNAAVARGQSGVVGEGKNIWPNIHVEDNAELYIAVLDAIRKGADIGHGREGYYFAENGEHSFYEVARAIGEVLVSLGISSNPEPTTFTREELSKYLGVDIATEGSSLFGINARCRGTRGRAIGWKPRYNKADFLACVKPDIEGLVTRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJM8</accession>
    <name>A0A9P6EJM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJM8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="18732" checksum="D51D7E280109D97B" modified="2023-09-13" version="1">MSGYSLNPLLAYTPSPLPSTSPSNIAVGGTAIQRQQLLPLLLLLDLVFTRTTPTSSKDPFMFQRQENSPDSILQHHPRWHSGRRWSPLDGLSSWLLPAQRPRPHRQCRGIRPTVCPLLRIMTIMVTLFMALGSMFFTFHCRYTILTAEVQNDPLVLRSSYSQTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJT5</accession>
    <name>A0A9P6EJT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_810994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJT5"/>
    <dbReference type="OrthoDB" id="3256413at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="679"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="798" mass="89305" checksum="4845D53320A94DFD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK41</accession>
    <name>A0A9P6EK41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK41"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="23781" checksum="E8B4D368BAE4C407" modified="2023-09-13" version="1">MFHLSGIALKTSLVRSIAFCLELETIRLMDVSQQFVCVDKILSLPSLKRLSLHIPDGTDFELKNATFRPSITALEIPGSSSIVYSTLLGLKYGEELEKLTINITSCNPGTSVNDVILDTLVPLVTASSNTLKELKFIAESGGESENLAEGTVAAFGRCVGLHTLQLDTSLIFNFSKQFRGFPEFSPLTHRCLPCNNPSNALSNCELWLLARAASSQNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKP1</accession>
    <name>A0A9P6EKP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_882092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKP1"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="271"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="623" mass="67892" checksum="E693853E0AEC293F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM35</accession>
    <name>A0A9P6EM35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_891735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM35"/>
    <dbReference type="OrthoDB" id="2921803at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="40233" checksum="CBAAA3730021C576" modified="2023-09-13" version="1">MSTSSPPFISNKANKAFPTELIDQIIDYNHDDRNTLLAIAAVAKQWTASSRFHLFSSIEVSYDNGRQLIQLLSSPHCTFAATIRRLDIRLVGGSQKWFGEFSKRLKQFDKVIIEALGLMGSRPTVLREEARTAAVSFYSHLRELIIGPLVMETSLEFAALVTGLSNLQSLSCAVSFQSAPSFTQAQRLHLPNSLQIVELTSPSIKSILELFDQRLSSITSLSLIFMTSGDYPYLKAFLERPNNILRALKITMDANISGVSLDTFAELGFRQLTALRVLDIQTTPCMPPPMILNILKTIPSSNLRKLKMTPCLTADIVQVDEMLSGGSRIFKHLKKVAIVGEDLTAVRQSMPRCASQNLLELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM42</accession>
    <name>A0A9P6EM42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS polyamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_849016</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM42"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="79"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="537" mass="59350" checksum="8BE0250DE14E13FC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMG6</accession>
    <name>A0A9P6EMG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_75568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMG6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="13007" checksum="71919FF680572F9F" modified="2023-09-13" version="1">MCSSVDWDLDYKRDVDVDTFGFRFSIFCQSLSIFFCQRFRDSESPDVLDTSSSSSHLIFLISSHLISSSSSHLIFLVFLIFFISSRLPHLISSSSSHRTLLLYTPRFPSSIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMJ7</accession>
    <name>A0A9P6EMJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMJ7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="295" mass="32329" checksum="BCA59F57751CCA3A" modified="2023-09-13" version="1">MVLKVALIRGSADPYVQRRFLAQAIGVQLPLANITHAACEWHLTRGEKWKAQVVLEFSSTSEEKQVHLQSNLCYRFSPCKSALQLQSTLHLANIAASSPTALQTSIIKFHSGLPGSFLKVLAAMSEATMVVHTKVFIVSPAVLSPICLVELPAWDSSSGPPQYSATAANVDNAYDFYFLLLNSFGVSSRMVTGLNDSSTEPEQISYRWERHMHSHIGTHVLLTNGLAYCVFSGRFVLANHIYHGSRTSIDGCGFKYKVLVISRFDVCSALANINTSCLMGHNVPVVSTLSPRTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENU2</accession>
    <name>A0A9P6ENU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">General negative regulator of transcription subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_950981</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="12">
        <location>
            <begin position="473"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="11">
        <location>
            <begin position="664"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="10">
        <location>
            <begin position="859"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="9">
        <location>
            <begin position="1151"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="13">
        <location>
            <begin position="1393"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="8">
        <location>
            <begin position="1743"/>
            <end position="2098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9532432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2101" mass="237964" checksum="ACF853D2699AF18F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP86</accession>
    <name>A0A9P6EP86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Translocon-associated protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_890781</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IRC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP86"/>
    <dbReference type="OrthoDB" id="1926781at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924:SF0">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="201"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="25777" checksum="EE8587F3C3E0CC47" modified="2023-09-13" version="1">MAAETENTTQKAVSSDPEVLAIATFPESNVFNHVTNGQKTNLVITLENKSKHTVTLQAISAALLNPDTNALTKNLTSMKYKAPLLENVKMQIPFSFYSETKPGDHRLNIWVEHSTEAGKFKVEAYDGIVTIVDPDFSIFDFKLLTSYAMVLLILGGAGYAAYVSFVPQPKKGKKAVAGTSSVSEPVAVTATGAGGYQEEWIPEHHLKKGKGGKKTLTSGDELSGAETSGTEGRRRKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP88</accession>
    <name>A0A9P6EP88_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_580455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP88"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="52695" checksum="2B8A2BB43D667672" modified="2023-09-13" version="1">MSSTEHRVLVDDTSQDINYVGSSWFADSTGSYDSAGNFGAPYRSTLHGTRANSSLSFEFTGTEVAILGTTSVRNDSGVIDPQLQCFVDNISIGVQQPFAYTENNWCLCKIENLVDGHHTITANVTVMKNQTFWFDRIEYKPSEEHNLAEQAISISNADPALRYGSGWSNLGGFTNITTKKGSSLQYEFYGVSLSWFGPILGELPPGQSMGTYSVDGGAPSTFLLQGRPKGGGTVFNQKFFETPKYQMGRHNLTVIYQGSESTTPLTLDRIIVQNGTLPSQPLQPPPVAASAKSFHVGGIVGSVIGAILAVAIIILVSIYLCRNPRKWRRLKEKHCSRISPPMIEPFRYVPVQPSFPQPIHHAGEVSSWSGSGHGLTLQFNHLPISRVGHPSSPMYRMSGDSTNASPISGPVLHYPISSKAREARLSRQRSSPSVPHPRSSTITSLPSPAGSGRYLMHIDSGYRLPDSPMLETVEEIPPQYTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPJ4</accession>
    <name>A0A9P6EPJ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_587956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPJ4"/>
    <dbReference type="OrthoDB" id="2882635at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="19092" checksum="97E09069EFF51877" modified="2023-09-13" version="1">MEPSTMESSNQVDGAVVIENHKTYYYDLVVFEKVRFLISKNGFLLENPKFFDQFDLPKRSPEQEEGVDSIMLKDTTSETFHGLLLAMYPFPRSAWSYEEWPGALDLATKWDLSKIRAGAILAISGVHKNGAKLMVEIILLGRKYNVAQWLEEGYIGILKQADLKDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPX5</accession>
    <name>A0A9P6EPX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_591957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPX5"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="83"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="567" mass="63926" checksum="C7D5A1E99E479B70" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ59</accession>
    <name>A0A9P6EQ59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="2">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_419031</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="2"/>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ59"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF19">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040238271" description="AA9 family lytic polysaccharide monooxygenase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="4">
        <location>
            <begin position="20"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="25525" checksum="FB63BD26E63EA673" modified="2023-09-13" version="1">MLSASLAVLASFLVSQAAAHGGVTSYVIGGTTYAGWQPYNSASGQSSIERPYSTYDPILSVSSGSLSCNDNGQASGSQLSATVAAGSTITAKWSQWTHAQGPVMVYMAKCPSTCSTANSNSLDWFKIDEKGLISGNLPNGQWGTALVMKDLAWTSTIPASLAAGEYLIRHELLALHQANTPQFYPECGQLKVTGGGGKVPGSGYTVKFPGGYGANDPGVNINIYATESQTITTYKVPGPPVWNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQE3</accession>
    <name>A0A9P6EQE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_942961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQE3"/>
    <dbReference type="OrthoDB" id="2928561at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="12295" checksum="692780A4BB7AE001" modified="2023-09-13" version="1" fragment="single">LLVCNWTSSQQCQRSSTNKCIVSTSEGNNNYLSSNRGVMFDYSKNLIITGGTFTVIRGGSKATLDLLAEKSAPGAFHCSQERSDPPKCLAETRVFVIDNIMEQIDAVVVSCII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQX4</accession>
    <name>A0A9P6EQX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DHS-like NAD/FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_407337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQX4"/>
    <dbReference type="OrthoDB" id="2919105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031508">
        <property type="term" value="P:pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF15">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="23"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="440"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="594"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="756" mass="83283" checksum="AF1F0AA82E2973C5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER08</accession>
    <name>A0A9P6ER08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_890105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER08"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="356" mass="39419" checksum="032FA051DD9D8800" modified="2023-09-13" version="1">MSNLEDLGNVTRLSNQVVRVLGQNPGKFTLQGTNTYLVGSQNPYILVDAAQGIPEYIPVLESALKDIAKPANSSQPDISDIIISHWHTDHVDGLPSVLALLQKLWESRNPETPYSPPRLHKYPIADGLQGGHTLGHFSLPKILSSLLPGQFTPSPNGGVIHDLSEGQIFKDHTGTTLLSVLHTPGHSVDSIALFVPQDRALYTADTVLGHGTAVFENLTAYLLSLKRMRDFEVAEQRYDILYPGHGPVVKNGRETITTYIQHRLDREKEIMGVIKTAVPDRLLADKVSATPSDAWTTWNIVRLIYQKYPENLWLPACRGVELHLRKLQNEGMVVQGEGEGVDTQWKFSDTTAESNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER31</accession>
    <name>A0A9P6ER31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_471711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER31"/>
    <dbReference type="OrthoDB" id="2990415at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="261" mass="28754" checksum="3C6004911642C46A" modified="2023-09-13" version="1">MSPSKFVEPTPSMPYSPMLSMPLAAPFVSQQWSTTGSQALVMPPSNYGLGARTTVSQPQFSSKPTLKKVETKVVHTPTNNASTSSAKPVASSTQRHIPPHFVILVQSLQANRNSGERRTLRTDLSLQIANDGRTYERAGVTKFRSYLNLAVQEGIVELGGNDADAWVRLRPDWYNAIPTKPIPSEFVELVKALQAFRQEGIYKPVRSQVASQMSKGVYKKAGVSKWSQYADLAVSEGIVKLGVSDGQDWISLHSKWHHAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER68</accession>
    <name>A0A9P6ER68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_480643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER68"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070880">
        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="2">
        <location>
            <begin position="125"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="759" mass="81354" checksum="0F745D84EDEBD8D0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERB2</accession>
    <name>A0A9P6ERB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_409886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERB2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="10885" checksum="5284904C3A033601" modified="2023-09-13" version="1">MLSPLHSHPRQQFSDRPVRSEDRRQSSTNHFLLEETILLCSLGCAGNKTQIQRILDLEEYSRHLSLCGQQRTTAEDSSRSQHASVKKEKETPPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERK3</accession>
    <name>A0A9P6ERK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial adapter protein MCP1 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_873589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERK3"/>
    <dbReference type="OrthoDB" id="10259513at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039960">
        <property type="entry name" value="MCP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409">
        <property type="entry name" value="MDM10-COMPLEMENTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409:SF1">
        <property type="entry name" value="MITOCHONDRIAL ADAPTER PROTEIN MCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="25922" checksum="A19C40AFD3BEDCEB" modified="2023-09-13" version="1">MSSFERLRTNTLPILTKTAHVTAPFITIFLLIHLAAPASATVGGSSLSTQTMLLGREYYQSRLTEPLLILGPLAVHSLSGTFKRLLSPPGKPPRPLKRLLSLTGYASMLFLLPIHFLVHRVAPTNELPPIDALGPSELDYEFVKAGLHTWPIRSWLLYGGLILSVTAHMADGVGIILSSWSVPKLPSRLTRTVTILATVALPTLLGLYSLSTEPSIVFSSMQSRFKAVFMMSTIYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERN2</accession>
    <name>A0A9P6ERN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_419477</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERN2"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="258"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41225" checksum="60EE1C95178D99E4" modified="2023-09-13" version="1">MNSLVNQTHAATSSCPARPHMPLIKNTPRLQCTIPNPPLKTGHLEPSLETSTLAAMLDMDNKLIGSTPDGDQSNIDHITILERVVCSNFSCCGTQHSDLHALLAHFEGDHVVVLAPNGKRVFPVALHPSSGESTPASSRSSSVSPSLPSSPITPPFSIPSSPSDAKFSISLANHQSGRTVPPVYTPFTPCWPLEPAYSLPDHSEIVIVQEPTFDFSTQPSLLPPLQLEAPATVDSSESEFGDDEANILTDDDVSLSLPVSNLRHDTPQRHSEIPKAIRSTKEKRGGGMFESSAQHTTSSKPSKSRRGVSSSTSHSRRREKMFRCPKEGCVKAYLNPNGLKYHLEKGTCKLEDDDAQSTSEKNPNRLHQLHPGDHPRLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESN9</accession>
    <name>A0A9P6ESN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESN9"/>
    <dbReference type="OrthoDB" id="3005190at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59706" checksum="3EBF1809E2D681FB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETE8</accession>
    <name>A0A9P6ETE8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETE8"/>
    <dbReference type="OrthoDB" id="2879636at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="38155" checksum="F1EB19AD4E802214" modified="2023-09-13" version="1">MQKRISIGKADNITRGQPWFEDGNIVLLTHENPTAFRLHRGVLGRHSEIFNDMLQMPQPDTLNIQHFEGCPVVVMHDHPTDLSSLVIALYDGPYFANTKIEDFFYLCSILRLSTKYFISNLRRKAAQFLEQTWSSSLKGHDAMVEAALTSPSINGFTYPFVHPLHVLNLARETDVQIVVPSALYFLSLYPLSDILKADHPKLLYEHPSKPASTLSSSDLLLYSLMYQHRLQIMSTFIRNFCTIRVAEPPCSSSTCGKSFSRLVSQLHRSWSLRTGPLHFIAQAIQQVSGDQTICSECRTEFAAEATKLRKQVWDELPSVVLLPSWDQVMRPSSIMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETH6</accession>
    <name>A0A9P6ETH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_204366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETH6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="171" mass="20147" checksum="974F313E539FE5E4" modified="2023-09-13" version="1">MVQLSPSCYFTRFQQPTKLTRKKIQTELKVPEQRIMQLHVPRIVSFAVVFIVALWHYRTNSGSYKCNIIELSGYVVEVQGLYTQIDITRRTRNFRFRTSRFTTTRAVLFNFEVPPNVVNYWVLALLVWSFPPLPRWHSGTDHERPVIMGAADNLTARVKIFKEEPGLRFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUA5</accession>
    <name>A0A9P6EUA5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_912535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUA5"/>
    <dbReference type="OrthoDB" id="70823at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF44">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="443" mass="49262" checksum="ED326A7116452664" modified="2023-09-13" version="1">MTEQENVLPLLARALQRIRLTPPRIISSPPTQPRRAAVALLIRVVPAPNTPLPPTQEKPLDLDKFFTQEWVNHPNATPEILFLHRETPTPATSDGSLWQSQKKANEAHIAFPGGRQEPDDEGGLYTAMRQTWEEIGIDLAEPCYTCVGQLDDREITTSLGKRLLMILSPFVFLQLTPSAPPADPVETTILHWTPLQELVSQHKPPIWSTVTVDAASRLASKHSAVLRLLVRVFIGSMQFPAIVFRDFGVKPTDEKRESRQPSKVLKLWGLSLGMTLDLMSYMILQPPPPISRNSSSTHVPSAVASAGNGNVNGSAQPDYFARPSSASPTPSTPLSEVMQLPYLDGQDFRMEYVAPSLASVFPRFSYPDVNFWIWVFGKRYREVIRGWEASVRGGSANDRRINWSGTALSTFYASIRKALVVVIVARALGVIFGVSFALWWIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV64</accession>
    <name>A0A9P6EV64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TMEM205-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_888178</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV64"/>
    <dbReference type="OrthoDB" id="1641132at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="TMEM205-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053009">
        <property type="entry name" value="Xanthocillin_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT PLANTS LEA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241:SF102">
        <property type="entry name" value="LD23009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM205-like" evidence="6">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="20453" checksum="570A3C7A237F15C1" modified="2023-09-13" version="1">MAKADLLSLGDILSVDGLYLLGYSWLFGMSVWISFFGGVIAYKTLPRQQFGQLQHKTFPIYFVLSLGISSSLLAIWIAKHPDVTSQLTRPTLADVAQVYALGSVLFNQGLNKFVVGPLTSSTMFARHKLEKEEGKVYSDPGVSQDMLKLNRRFGMLHGISSLANLFSVISLVFHGLYIGKAGVKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV71</accession>
    <name>A0A9P6EV71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_728501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV71"/>
    <dbReference type="OrthoDB" id="3254233at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="161" mass="18244" checksum="D50C5FE18696F77A" modified="2023-09-13" version="1" fragment="single">PLPSPPAHLLNNPEIKATLQNMHHFIKVDTPFNITRFKNLLHDHPNQPFVNSVVRGLEEGFWPFEDGEWGPNVEGIAENFASDERDLDVIRAHRDKEIAADRWSDPLPSADLLPGMKSSPMFVVWQKGKPRVITDHSASGINDGIPREEARVIYDDMRTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ02</accession>
    <name>A0A9P6JJ02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_840490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ02"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="33"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="255" mass="29060" checksum="2C166E085DBCD0B1" modified="2023-09-13" version="1">MPRAAAHSDSEDSTKLKTKNADQEDDEQSEEEYEIEEVMDAKRGVFPDGQMGYFVKWKGYGPDENSWVVEGDAENAKDLVDEFWRKNPAKRRDTRKSVDKKTIEKPRKSTSVVPVDDSDAEVKPKKRGRKSNASKPAESDDMQVDRPEPAAKRKKVQTPKKARSETPEAPVKLIGNMDKYKNLADWEGLVATVDTVEQAPNNTLQVYFTFRALISNQRNSGESVVENSAVCYKRFPQTMLMFFQSNLKWKTVDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL75</accession>
    <name>A0A9P6JL75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_838413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL75"/>
    <dbReference type="OrthoDB" id="3359887at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="332" mass="37602" checksum="62D47D342A912492" modified="2023-09-13" version="1">MLELQVDFRVVENLSLFASAVDYAMAVEGRSELDLWNLREEIVRFLVGFERLYIGTKPELNSRARLCIFQLIHIPMHIKWHGSIRGGSQATVERSIGEMGRKIKSKKSPFANLTNIIIRRERTKILSLYYPNLFPSPRSARSDHSSANTKLFHQANIRKHDLLAESGSAAFQELVALVSFLGDCAQDLSDEHIQRWGKLRLHNKRVLQTQVSYTKGEPARKSCWFSAVDVHNDLIFGEALAFYEVDFQSAHSASSSYVAFKMLKGVHRILSCIRGRSWSSDICILPVDRIQDIIGIWDAQSYIYVLQKHPGLELLTVVESGVNEGLGGQDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMJ4</accession>
    <name>A0A9P6JMJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMJ4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="Invasin/intimin cell-adhesion fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="11054" checksum="815F7E80228B5129" modified="2023-09-13" version="1">MTPTSGNSQIVAFNSQFQPLVVTVYDKGSNPVHDSANTQVTFQCSQPYLATFPGLSATATSPTVQGVATSPAMHSDNTNAMGSFQVTAAVPSSPLNPSVTFNEAVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMK9</accession>
    <name>A0A9P6JMK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MBOAT, membrane-bound O-acyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_771391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMK9"/>
    <dbReference type="OrthoDB" id="420606at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051085">
        <property type="entry name" value="MB_O-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285:SF18">
        <property type="entry name" value="PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="65466" checksum="91AD36B759813D7E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNL8</accession>
    <name>A0A9P6JNL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_450813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNL8"/>
    <dbReference type="OrthoDB" id="3026402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040443939" evidence="1">
        <location>
            <begin position="21"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="71" mass="7226" checksum="AB68064796C8B239" modified="2023-09-13" version="1">MKFAISTLITALVVLVQVSAEPIPTPQTSQAMHCNGPDGLVCPTGFRCCGPFLGGVGGTCFQGTTGICPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNV0</accession>
    <name>A0A9P6JNV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_908010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNV0"/>
    <dbReference type="OrthoDB" id="3237202at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="445" mass="48135" checksum="941EF90D472D9AD1" modified="2023-09-13" version="1">MLTLRGFSACIETNGTPLPEYLVSVDEKSSKVSCWIPGIESQTFKVHWCDEGSKVSTCAFIILDGVVVPGRFLHGEGAATRGGVRVSKTTERPFVFQKVKETGSEIREDSKEAGLIVLKIKRIKCVAPRAPNAIQSEPAAGALGMRQTGDLCVGFGDEMEVEAQHGATWEVASYESEKPGTKPRTFVSFAFRYRSPDFLDAQGIAPMEQTQPWLAHTRRLATRRTVSLPLPMLKLEQSELLPPSAPNSANSTPDSSFLKMGPPPTPLSRTTSISDLSQASTPGSSSASEPHSSPEQPTNALSLFIPQLTTLIPTDSDSPQGITNTDVSEPSPTASEVDASNHSQAALGKGKPFGWRPWINPDVRAGDPRRTLSWKLPKENGSSSRSVRGVERKASTSGHESTPGSPQIYESAFMVSLPRQNSSTTTNTLRKELEEHHTSAKLRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP03</accession>
    <name>A0A9P6JP03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP03"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="259" mass="28500" checksum="37D15CBF41D1A952" modified="2023-09-13" version="1">MASNVATAGSASSTGPQTSSSYSSEQRFLRVTGHGKIRAFVAHALEFLDDEDGQEILPLPARTLVLHTLPVQIDPRHIENPITLPAASANVTPTHVANALSTIPRLVTVAEIIKREYVKLLETKRSMRLKGLYQYNQVRLLEDVPGVIIAHEEEISQAANLQETAEPESDAAVKAKKKQQAERLRSKQIIEALSGKNHPRQTQSPYMTITLSTVEKTELLKSGATYQPPTIRKISRNAKQRAKKREKKLAAAQTTEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPF2</accession>
    <name>A0A9P6JPF2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPF2"/>
    <dbReference type="OrthoDB" id="3055188at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="196"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="446" mass="50476" checksum="886BD4FA2F4FF8F7" modified="2023-09-13" version="1">MPRQTPPSGNHSRISKENVAPDVAQATSRPSKASRSHANILHNAAHDLKTTGAKRNRAFNDIGSQSENHAPPKRLKKDNTYDMSFTPTHGSSSTEKVQLGAYTPLLASNISRHSASMIRKPEPTPLYTNQLHQENGDESETEEESIIDDNGGREITEDDYRHTDALEIQHTRSQNALDVSKPHLQPDAIHGTILNEAMRRLREYMVCVNCFPSMEQASACLNDAVTILKADEQIANIDDIQTDLMRTEVINEASRYLNVLKNICIKSVKIYYADAVYPPEYIEGNQQGYFNLIAERIESLIGEESLFHLGEKDDEGRHSNMMHPCIYHVCLDFYYGSGPDALALQIPYIFQDSIPERAVALVITGIYNALDEYRSGEYIEKELTGDNDCQEDYEAAIDLIKAIKTSPYHNDKWINCRRQWALDGRNLLKPAKPEKKPRKVFRPYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPQ5</accession>
    <name>A0A9P6JPQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DigA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_855678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPQ5"/>
    <dbReference type="OrthoDB" id="1845386at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="10">
        <location>
            <begin position="61"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="651"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="11">
        <location>
            <begin position="899"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="958"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="853"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="965"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1114" mass="126057" checksum="73B075E6D4C66D06" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRW6</accession>
    <name>A0A9P6JRW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_762786</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRW6"/>
    <dbReference type="OrthoDB" id="431212at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005345">
        <property type="term" value="F:purine nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015853">
        <property type="term" value="P:adenine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015854">
        <property type="term" value="P:guanine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF1">
        <property type="entry name" value="XANTHINE_URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="60409" checksum="59BF2C78A11E12E2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRZ8</accession>
    <name>A0A9P6JRZ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MutL C terminal dimerization domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_762482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRZ8"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.100:FF:000001">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="2">
        <location>
            <begin position="175"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="383" mass="42546" checksum="3DA27511C526C282" modified="2023-09-13" version="1">MDELKKDLPPQGGKAGALDSNPPLVGNNSPENPSPISESPHHNHPKTLDNTQTLFLEDDEDEDPNSILSQAKATSSVTSTTVSSKNSVIRPEIIRTEKAGSDIVVRFNIDNVGALWNLKTTQSSSFLDDVVGGEVDAKKLAVPVEASILNIEDGDNAERALSRIINKTDFNSMEVVGQFNLGFIIARRRTRNSGVEVDKKMDDLFIVDQHAADEKYNFENLQATTKIEAQKLVRPRPLELPAADEMLVIENLEVLRQSGFEIMVDEDASESHGRLKLSAMPISKNTVFDVKDLEEILHLMRNRPTGQIVRCSKARAMFAMRACRKSVMVGMPLNSAQMTSVVRHMGTMDQPWNCPHGRPTMRHLCDIRSSGIHPKDKIDWSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS31</accession>
    <name>A0A9P6JS31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_904609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS31"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="414" mass="47444" checksum="98A8791D60AFCD9B" modified="2023-09-13" version="1">MKLHFEFSDRTIYDIVHPCITTIFVCSYIAIHPDVPGQKDRWFHVLLRKLGIALLMLLVPELVIFWPLRQHMAAIVIARAYKNRGWTRAHGFLLAMGGFALYDGFTHEYIETLTLERFDELVESGEIEFPNITAERVGELGKADYFSKAVVVLQTTWFVTQCVARVVNKLALTEFEVITLALAILNAFMYGLWWDKPMDVGMPVQVYRRTGHGQYTPKSDKNARPMNAWSILGELTMIPTFTKLIGAYQPLEEDGRARSFITPSFDNLDTLNGQSLRRLSRGHQFKIMSVLTAVFILFGAIHFVPWFYPYPSQLQKWLWIAGSVSIVLFPIGALIVFYPMAGLMVRWKMVTDRYLLLYRIALTSTILSYFLSRVIVLVLPVVELFSRTEEGDYFIQTANIGTAIDWTGFLPHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSC2</accession>
    <name>A0A9P6JSC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSC2"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF2">
        <property type="entry name" value="FE-REGULATED PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="468" mass="50961" checksum="1C49C1348ED24480" modified="2023-09-13" version="1">MGGGLAPDSNTKTVVILGGAYGGTRAAQVLAQGLPASWRIVLIDRNSHTHHVYAMPRFSVLPGHEFKAFIPYTNVFKTPAGPNHIVLQAHIISMRPHHITLSKAFPEYGFSNEVPFDFAVYALGSRLPSPLDLWGTTPHGTPVTLPTRLRELVVPLPSTVYTGDKVQGCQWLLEKQKIIETAPTILVVGGGALGVQYATDIKAVYPTKDITLLHSRLQLLNRFDVKMHDESLKVCQEQDINVILGERLDMSSVGDLGAGNIIPLGKKIVRTITGREIAADLLILCTGQTPNTSILQAMDSSVINEENRRVNVLRTLQINPVHVSCGPNGQKVLPNRERGATPYPYIFAIGDAADAFGAIMAGHTAYYQGEVAARNIVRLVKRREAEEKFKSSVMTGVEDEDSEALMDDPLESYTPGLPAIKVSLGMTHSVSQLGEEVSTKDDGVPDMQVKSIWKLMGVTVNSDEDMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSC7</accession>
    <name>A0A9P6JSC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein MON2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_850328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="294853at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="7">
        <location>
            <begin position="4"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="5">
        <location>
            <begin position="204"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="6">
        <location>
            <begin position="1101"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="6">
        <location>
            <begin position="1417"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="703"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="983"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1595"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="703"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="983"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1595"/>
            <end position="1616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1865" mass="203307" checksum="C9449FF4FDFFDF41" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSD3</accession>
    <name>A0A9P6JSD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate-binding module family 13 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSD3"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="12644" checksum="8F251E8FFFADBFDF" modified="2023-09-13" version="1">MDVQGAVYANGTPVQIYDCNGTPAQKWVIDHGQTKVRVAGTNFCLDRGETPGNGIGMKIWQCYENQPDQTWEYNASNQIGWDGTCVDLTNGVTTNGNQLQTWECATGNNNQVWAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSL3</accession>
    <name>A0A9P6JSL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_892162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSL3"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="50959" checksum="06C8BDECF29797DD" modified="2023-09-13" version="1">MSTLEKEAKIEGQKRLQAMKSWDKSSTVNGPPAKFFRETLRNDTNYITAWTGAGFTNQFMGYTNLIYLAAITDRVPIIPPFAPNPHINVSAGVLPFGDIFDLEQLSMHLRRPVLEWRDVKDLPKPRDSNPFPYVVNSPSYSPEPIGCWSTRSLLDRGAARSSHVIAHIGLDASYTRVHNNTRLKPDDPHEPHVVFSHLAALIYRHSSSTSSDFASPPFPDPGLHPHRYEFIESGLEADHHTRMPDSHLACFDSLYFSTSSIAPMEWRFKFSPAWRDVGQWLKFSKKATAILDEYMDALFPAGPEDDVDEYPPFIAVHVRRGDFDWDCRSDHCLPPLSVYQREVDNIKQELSEKRGIDVKDVVLMSDESAKEFWDEATAFGWLSINHEETQTSEKFGEWYPAIIDVAIQSRAIGFVGTEHSTLSLVSQRRVETWNAGIVRTVDPRSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSU4</accession>
    <name>A0A9P6JSU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Osmotin, thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_833904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSU4"/>
    <dbReference type="OrthoDB" id="2909458at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350903" description="Osmotin, thaumatin-like protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20470" checksum="1D86E79ABD77C324" modified="2023-09-13" version="1">MVFTLKTVSWLSLLAIISGAQAQQPTTDYTFVNNCPTAIKLYRHNAFSTDLAKGANVTRQESLATGYFYTDANGGGGSQTDPSTKFATYWAENDPKYYYYIVKNTTSFNTGMRIEPSHPEVDGFCQSVTCDAADCETAFPRRTVFTDLGPISPTPPTEPPSPPLYSCPFEGVTYVVTFCPSGTFPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT88</accession>
    <name>A0A9P6JT88_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT88"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328">
        <property type="entry name" value="ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="28050" checksum="245444DE56F8BC1F" modified="2023-09-13" version="1">MDNHQYQPLEFKDKEPFLRLEKHKNIILTPPRPDDPPAFVPPMNDPRVYECLSTPPFPYTLEHGEGFVNGLLKDYKEVCKKLDGAKDIPESIMVDYCPVRVIREVQENGSDILIGDIGFFKWRHGELMAFDGTVDWTLKEKNEEEMAKLPIGDPKIVWALGDFLMPSHHNRGIMTDVVDTLLKKWGIPRMGIRHLCVDVFTDNEASAKVFLKNGFKSVGTFPDHVVSRGKKRGLNVLEWKYEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU89</accession>
    <name>A0A9P6JU89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU89"/>
    <dbReference type="OrthoDB" id="3269357at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="51432" checksum="EEDD79E60181FE50" modified="2023-09-13" version="1">MIDILKYIRCFVFLVFVISNAVTTSVAVWNLSIIEGNVLYAAAGRIDTYLIILGSLGLLLIFPIIFLEIYGKITILGKVWFELLWVGLFGVMELVGASFTTSQSTSSMCAERQIDSEDQTSPCTSTQVLIAFTWIPALLLLGYGTLLLILAFVKSNEDRSVWTSGVGTYPWIRGVHNLKSAPTSPQRPMFRSKTPVIYAPRPRRAGAPVLAYRSGIDSEYDVESFRPSPPPGPLSTNMNIMSVERPMPPIPATTADSTFQIKPFKHQPVQMSQPVFSTPFYHSSVQRVIEERPGLSSVVPQAPPAVQLGQVRRLPPSPPPLGDWPRLDATSRPRTKKTLPPLTIPAPAPTSASIVQPSRSQTSFAPEPEPQPPIHALPPPPQRQSRRQNPLPPPPPPQSLVSPPVSSGLPYLTTSIAPLQPRRARPSGPRRVSSDNHDDPSSSTRRTVAVPPPLDLSKISSYTTNPSAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUL9</accession>
    <name>A0A9P6JUL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_845829</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Vacuole membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUL9"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="4 12" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9533103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="16211" checksum="4FD49BF13DAD8A1C" modified="2023-09-13" version="1">MSLCPPFAPFFGFAGVASAMIFSTVGAALGTSKSGIGIAGLGTFKPELIMKSLIPVVMSGIIAVYGLVVSVLISGSIKPHGYSLLAGVVHLGAGLSCGFTGLAAGYAIGIIGDTCVRAYVHESKMFVSMVLILIFAEVLGLYGLIVALIMNSRVSTMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUT5</accession>
    <name>A0A9P6JUT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_541873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUT5"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="34847" checksum="D95E2D990D09E8D9" modified="2023-09-13" version="1">MSSEIPLHTIWYYSTSGQILAGCLAVTIWDTLCHFLDDFQILFFQKFSWTTVVFIVARASPIVYFIALTMFTASIDVNCGVLQIMYRVLLVLARTSTAFLLLLRVNAIYTNKKPARIFFSMLWFMTLGVFLLLAIDGIKIDHPSYYWCSSFVQEIFIAPAVLVEMLSDTLMCLAILYELGGTSWKERGRLLMKLFRPHHPYLTDIVLQDTLIYACLAVLSNLALIFGTVLFGSGFSENITVAASHPSAVAINLISLRVHRNMKLGTPGLVAPATPSAPNQISHLVFNSTHTDGTQVNNSTGASNTEEAENEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVC2</accession>
    <name>A0A9P6JVC2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVC2"/>
    <dbReference type="OrthoDB" id="3367070at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="484" mass="53328" checksum="F246F44A43B85100" modified="2023-09-13" version="1">MALAQRLNDLALANSNGLLNDDEYRLLRQNVFEEYSSNVVIPVEAPVVPIAARLDVHVRTRPSASRATTSPSLNHQRNLPKHSHDSRKSIATPGRQKSSVTSGVASLIRKATGRRTPVSIHEPSTTPARDSHKLDIAEHDSPHKFMVILPKLLQRKPSTLRKDPPKLLSDTWSSSRSTNTSSSTSNTSHSISLLTPTRGYLHSANVSSSSLRLSHDKSPSTPRDVFDDENLDTAKDIHGNILITEDELQTLTDAFNNLESTALRRVQKQRARRLPINTPSSVDVLLEGREWREHRLIPSSSSPSLDASRRRSRMLRSFDSNGSGDGHSIRSSSSNQTNLSQSRSVTSIPRVTPASSPLSATFPFRNTTRSNSISSNSSHGASSFTSGGMLAPTPTVVSLTRSASHLCLRRKPKAPAGSGITSVSQETIYRPSHDLGDDEDIEDDPELVDIRRRRVEVIARYTARLDFLRAKLKGAELHEKLLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVN9</accession>
    <name>A0A9P6JVN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_842772</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVN9"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine/threonine-protein kinase haspin C-terminal" evidence="10">
        <location>
            <begin position="653"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="40"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="234"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="754"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="800" mass="89109" checksum="9075E3392220E903" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW44</accession>
    <name>A0A9P6JW44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_843630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW44"/>
    <dbReference type="OrthoDB" id="2984728at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="11517" checksum="19319D8B4A016AC8" modified="2023-09-13" version="1">MPIAEGNIRHTASGRLNASFNVSGSTYHFSGAFVSGIQSFNTNNAKVTYTNVRDLTNTRTFSGNIGPDKINLIFQNGPVVSGDLDFPIYPGASVSGHGSWNQGFDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWS4</accession>
    <name>A0A9P6JWS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_830508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWS4"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="63"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="22423" checksum="09E4573508AF0FB1" modified="2023-09-13" version="1">MPKKQVSSERKQVQSHHPSNWPSVVRFIQSPAYHVSVPAAVRSHIEGSCISLKNNQIPISKDAKVVIRRITDTSHPAFGQFGLFAGQRIPPKMHIIYYFGEIHCDDRSDSNYDLSLCRLDGEINVGIDAHGMGNQARFVNDYRGIADKPNSIFVDGRLNSGALSMTIWSGNQEIKKGQEILVSYGKSWWQSRRSGPADGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BD59</accession>
    <name>A0A9P6BD59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_887957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158165">
        <property type="protein sequence ID" value="KAF9521280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BD59"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="149" mass="16491" checksum="BB96ED7E77B08296" modified="2023-09-13" version="1">MVIISPISSLKSADLVPGGVQLCERDLRRKIPTVIAGDMRCALTKSAVHQVIAFIRLQNASKPTSTQIGGKSRKLKIDLVWLLNELLLNLNLVWDEIPLVTYTLAVPTSLILSWSTWCNARMLEVPVVQELGGNSEISAHNKMYALRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BD73</accession>
    <name>A0A9P6BD73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_316822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158119">
        <property type="protein sequence ID" value="KAF9521340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BD73"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="16849" checksum="D952EAC4CAEE9C43" modified="2023-09-13" version="1">MNVQKNSLSRVSDKRSNGDIVLNRNTRRTSLHLFTETAFFITTPFTSSSTGFCVHEYLTGPFVSSNRSSRTSFAFLTALTSKTAFSLSTDVLGVVPSSRPSCSSFHIGSVASSTPPGVCGTNTSTATKTLPVFQPVDTEFSEDLIDGLHKYIYSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E0Z5</accession>
    <name>A0A9P6E0Z5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158195">
        <property type="protein sequence ID" value="KAF9521257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E0Z5"/>
    <dbReference type="OrthoDB" id="3149423at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="51772" checksum="0013AE339B943179" modified="2023-09-13" version="1">MGKRKSKGKGTKPKKGKKSKAEWSESELDVLRSYEEKWFLLSSPEDQNTLAYGEIAENLRRLSPEKYGVQVILQKRELHAEWDKKCSQIKSWYKRNRPAAKERRIFKFERRIALRTVVAHTKSAAIKAAVLEKLPDNKKEDQREYFKNFQTTVTEFMHQLSKKERKQYEAIRDEWQAEGPPADVQARNAQRFGYRCVEDMHKVANKQFGMLMITFTARPTRSGGWEYFIHDYNPNLNIPNNPILSMLGWAKPECRAFGKMFAKWVGYTDEAKAGHLSEDNGQSAGTNPGTTFALQTTNSGLPILPDPVLSSSGTEYFGTKREIIREFFVQHYRLATGKSTSRVPWGAMNESVREFIKSEFIPKKVLINDPGRMSSNHVSILLEHLRDRQKVEGIPTFLFHQFRQQDNSFAAVKYPTETLEDNEKSFENQAESVEPFLLIKYWAAILPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E334</accession>
    <name>A0A9P6E334_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase Rpb1, domain 6-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_923080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158010">
        <property type="protein sequence ID" value="KAF9521624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E334"/>
    <dbReference type="OrthoDB" id="3038905at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="14832" checksum="076CE06A3A2FCDA1" modified="2023-09-13" version="1" fragment="single">VDLQVKLDEEFGRLVEDRRLLRDFIFPRVSTNQPITSPSTFIAFQKPSDLEPAYIVDKVDELGKQLVVVCGDDPLSQEAQDNATLNFRMHTCATLATRRVLEKFHLTKEAFHWVVGEIETKFNQSVADPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3G6</accession>
    <name>A0A9P6E3G6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_730007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157987">
        <property type="protein sequence ID" value="KAF9521805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3G6"/>
    <dbReference type="OrthoDB" id="3211402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="17341" checksum="539DB309EA9FBEA3" modified="2023-09-13" version="1" fragment="single">APKQQLPKITWTPALTWALINQAQAKENRNVMLGKEVGENSTRDNKTQVLKRIASIIIPEIFGLNKDAAQKRIGTKWDGLKTTYKDHASKLRQIGAGIEETQAHAESGVNAFKHKYMDCYVPPDGPDAETTPRAKNLWDEITTKWPYFSVLHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4Q8</accession>
    <name>A0A9P6E4Q8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_917136</name>
        <name evidence="2" type="ORF">CPB83DRAFT_917867</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157943">
        <property type="protein sequence ID" value="KAF9522487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4Q8"/>
    <dbReference type="OrthoDB" id="2662268at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="20826" checksum="A07DF0DAA6F08582" modified="2023-09-13" version="1">MSNPLHCPLRASQQSSYSSLGGAVPSGTSSLIRRLPQAMYTPSGKWHSANSRPGSHPPVTFDYPGHHNQGVRMQHLIAQDCSGLITGGTDRVLAHTGLQKITFRIMWTGYTSDWVRPIEVASHGPITRAKLGQLVAQNFARFIEIHSSTKSSEPAWAAGHIRFDMLSLISLINTCDENWQADIYVDFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4Y3</accession>
    <name>A0A9P6E4Y3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4Y3"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="38161" checksum="C1B177F16F6891AB" modified="2023-09-13" version="1">MSGQPQATFSQGSHNVSVSDTTINSTIHIHGSQTSDYTYLVKQSRRALCMIPLRETLLRDAIQAPVNLPSKRYSCSSTIGSPQSGYVDIAQNIPGMKEHVNNTIDADPSLPSKSIEAQLIPLLVVPLKNYSPSLSHTIIHRIPLRFVVASRPEAHLEEYFKKEPLCAATSTFTLDDDYESMWKCYRDNFNQISNSRRDVIFGVPTSWPADDIVDNLVVRASNPWRFTAFSEMDALYTQIITICPSYLQKCFLRTVGAIIVLRGTTQAATTIAALSDLLNEKSSNITTILRSLRAVININDSNFHRTFYKLFSPELYIYHLSKGSSRTRLEQESCGSTYMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5D6</accession>
    <name>A0A9P6E5D6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157935">
        <property type="protein sequence ID" value="KAF9522748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5D6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040152181" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8270" checksum="34BDAE1D93DE770F" modified="2023-09-13" version="1" fragment="single">MPENAPFNCALLAAVIVLSQRLVLRNMNSSCYPYSLFILLHRCFRSCWEESMLTSGKSLHSVRIKLTGKLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6E7</accession>
    <name>A0A9P6E6E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6E7"/>
    <dbReference type="OrthoDB" id="2883672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="308" mass="34439" checksum="40529F1E44547A6A" modified="2023-09-13" version="1">MSKLDQKYAEMMENHPFGIALFHPPPSGTFKPGVCGYFDEYGAWNPICDLLDTKGLAAKGLSPVEQEPERAPLENGIKWGPQMSTDTKASKLNMKGGVAPQPGIPVNASAIYEYSSSKDIGAILLTTPPITHDRFYFSTPFKNWVKKNAQAILKNYPDVQEHQLWVVTSVYMTKSCAINMWNGHDKNFTVGFSVDAMGAGEAGTGFEWHHSQKDEGWSEYSPPGDQQAVVYFGGLVFTYHRSLFGKEDLRQKALAPAFSSGLFRGSQVLVKIEDPHHLNEHVTIRYNEVFEEADLELDIEDTEERKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Q1</accession>
    <name>A0A9P6E6Q1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YL1 nuclear protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_821215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Q1"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="463"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="541" mass="59995" checksum="85956CD623540BF0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Z5</accession>
    <name>A0A9P6E6Z5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_653772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Z5"/>
    <dbReference type="OrthoDB" id="2998673at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="392" mass="44470" checksum="27447431F2AA2B54" modified="2023-09-13" version="1">MNCALLTRELLDQIFEAVAQVDAEASDPSYERRPRSTLPSLARTSRFFYSSAIRIIWRSIPSLEPLFLCLPEQALLRQPPPPWSLFFGFFALTKNLDPAIFSRLEDLNRLRYHASMVRQFGFRTKQSYPKLRLGFDIASDIYDRLLPLFSAEQPLFTALTSASLHLSRFSGSGAYARLVLGKDCSLKELYIDCDAKLYDNDSLWMQWTSIIASANLKNLRCFDTSPFFEGCQEDIRCFPLRSLSNLFKSHHLTQVDIRSLVFERIDLIQDLALQPHLRSLVINLGGFVQMPPFANNSKEIYFPSLHGITIILAKLDLACSFLQQSQPPNLSYLTIQRQGKDNQWVMVDLLEAAQTSLPLPIFRQLVISNGQECEDKGDNQGVKASTLISSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7X1</accession>
    <name>A0A9P6E7X1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_638901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7X1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="18748" checksum="A8E0D688B707E612" modified="2023-09-13" version="1">MRLPRTPRFRYVGHSTLLRSTSLPLSEPRIYTVYFQFPEHLPSSFRIVQYRRSPLPHHNDNFIPTCVIICSVPIDGTKFVPHLKVLLKLYYSMSHSSRFPFSIVHALPCITYFTTIVICYQLGTGMRSAGSCVQRVWPAGRPSSVNVSGNCIISICVGSPSGSQKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8M4</accession>
    <name>A0A9P6E8M4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_606357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8M4"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF5">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="447"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="662" mass="72869" checksum="BD4511A16095E164" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8Z1</accession>
    <name>A0A9P6E8Z1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_609825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8Z1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040333628" evidence="1">
        <location>
            <begin position="17"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18321" checksum="B51E64880FA17A5C" modified="2023-09-13" version="1">MLWLGAGSWLLVVVFGSEKPEHIQGDEAALALDPIKYRRPPVPVFSSIQASMFDSSSNSWGSLSIIRHQTLPFKNASTTILNFDFKWSSCYTHSSSFFLQDINFQKRSQIRASRAQKEDSRFRRKFRWVAAVCSPSGRIQTFSMPTTTPQGSLIPPFRQSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9E7</accession>
    <name>A0A9P6E9E7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_752564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9E7"/>
    <dbReference type="OrthoDB" id="3033638at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="234" mass="26573" checksum="F7B8647ED7479863" modified="2023-09-13" version="1" fragment="single">FIVDLPVGEKKKVHQIAADAAQTWQSMTKEEQVAYTAPLLKDIEELCEMKKLSIHNVPMASFNDATTSLGHIEDEIRALHARTGTEVMLVAVRSDVDDYLRPLTIFSSERCLNFFRVGCNMELTRFAIRFEAYCVSGIDGVARNYVQETVQMKSEVASLIAAQLAAGCKVRISYQDFDRAITLKHSVVLEGWPLDKFCSPSDIPTRNDITILREAFRSGRARFRRLSTKEYEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9N0</accession>
    <name>A0A9P6E9N0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_570308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9N0"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040381034" evidence="3">
        <location>
            <begin position="18"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="24"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="536" mass="58472" checksum="92A0B498B48AFAFD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA27</accession>
    <name>A0A9P6EA27_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_772248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA27"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="16747" checksum="224B9E5B9AE54A0B" modified="2023-09-13" version="1" fragment="single">PYSLNPSRCGHTFCGLCILGWFFSRLHRHCGTWHESFGCPMCRSPLIITPERIPRLQLTFPFVPNRIAASVIESLVAKNTTESDLTDASSQNLGLPAWREDGRMRKDWSKKDRQVDCREEMEYLLSRWTTMQPQDFIAMKVKLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAA4</accession>
    <name>A0A9P6EAA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAA4"/>
    <dbReference type="OrthoDB" id="3261349at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="18"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="38957" checksum="A6A69BD48AE460C8" modified="2023-09-13" version="1">MEEEITFDDFKTHHYNYYVNVISFTILYYDYYLTFPVEVERMWRRGTGFSWAVGLFYLNRYMALFGHIPVVVEYFWRTSSPNKPRVSAICNLLQSYHQYLAIVVQVIVAALLAIRIYALYERSRRVLIFVLVVIFTALGVGCWSVVSQRRVIKPEIYVPVGCAITLNYDEAIHMTIAWGGMFVFDLIIFSMTLYKSLVLPRLRETSLLSILMRDGAVYFACIVASNLANMLTFIYGTPFTRGVGTTFTNVISSTMTSRLMLNLRHPGLVSNMKQSIHPRLTEDLGFYIDSLQTRQEYIRTSSTVIAPNNGRLLYDYLGESGPERPSTVATDHESVPVPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAD8</accession>
    <name>A0A9P6EAD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_859850</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAD8"/>
    <dbReference type="OrthoDB" id="2983126at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00878">
        <property type="entry name" value="Arf_Arl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9525298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="207" mass="23506" checksum="35351EA6F91128D2" modified="2023-09-13" version="1">MIAYLRSVVSTLVGLTRLGVEIIVVGLDNSGKTSILNRLTRRDVPNGVLPGTEKTIGFNTETIQHWRHSITIWDIGGQDKVRPLWGSYFWKAHAFVFVVDASAPERFSEAREELLRMPERRDIEKFPLLVVANKWDLVKDGSMTLERFRLEMGVDELEKLGMVIGIIVTSAMTGEGISGALDWIVERVPHQLINSRNEEKKHVITQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAE2</accession>
    <name>A0A9P6EAE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_897094</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAE2"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040546477" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="610" mass="67057" checksum="E1CA2B57F64D1400" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB12</accession>
    <name>A0A9P6EB12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_506289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB12"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="506" mass="56974" checksum="D6AD5C6CA08B0E78" modified="2023-09-13" version="1">MLQISQLLALVILIGTGYTFLNLRRRKLPYPPGPKSSILLGNAFDIPKHNIGRVFAEWSRKSNSGVVHADAFGRHLIVINSVKVADDLLEKRPELYSDRPNWPTIELLGWQNVSGLLPYGDLWRLHRRILHRNLEGQGATQSRPMIIDEVDSFLRNLLTSNADHLEQHIRLFSMSVTLLMMYGYKPKSLDDPIVRLADQNEKEGFSLLSFGGNLVNLFPFLRHIPPWVPGATIQKKAAELRKIMTTVMDMADSYSKQALADGSARPSLLTDFYSRKEGCGVSLEEEQAVRDATWTVYGAATGTIISTLGSFFYLIAKHPEVQERAQSEIDRLVGKDRLPSYDDRNHLPYIEAIYREVLRAKPPVHTSVYQVNQDDAYMGYCIPRGSTVLGNIWSMTHDETVYADPLSFKPERFFDSDGNLDDDTRILAYGFGRRKCAGKAVASDILWLTMASFLASFKIGPAFDDSGKQMEIDDAYEEYGPIIHKIPFHCSIAPRPSHTGLLVANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB63</accession>
    <name>A0A9P6EB63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_896816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB63"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="47"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25960" checksum="65BC63A119C3B761" modified="2023-09-13" version="1">MATSKSTASSSKPASDEVDIDKILKSEASAFQREVEVERILKGFKFNPYDILDIKETATADEIKKKYRQISLFIHPDKCTHARAPEAFDILKKAESDLSDKAKREELDAVINEARKQVLISLKLPVSTPETDPQLEDLEPSFKVRLRTYSKQLLVEEEVRRRTAIKNNLANEGLEAKKKEDEVSQRKRKAEDDKLWEENREQRVGSWRTFANTNKKKKKAKNSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECV2</accession>
    <name>A0A9P6ECV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="173"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="756"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="953"/>
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        </location>
    </feature>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1099"/>
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    </feature>
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        <location>
            <begin position="1674"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1689" mass="179086" checksum="BC6839A922FA532A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECV4</accession>
    <name>A0A9P6ECV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyl-D-glucosamine kinase</fullName>
            <ecNumber evidence="2">2.7.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GlcNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_794536</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic-type N-acetylglucosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.59" evidence="2"/>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECV4"/>
    <dbReference type="OrthoDB" id="311172at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045127">
        <property type="term" value="F:N-acetylglucosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd24007">
        <property type="entry name" value="ASKHA_NBD_eukNAGK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052519">
        <property type="entry name" value="Euk-type_GlcNAc_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43190">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43190:SF3">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase BadF/BadG/BcrA/BcrD type" evidence="5">
        <location>
            <begin position="24"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="39612" checksum="C7ECEDD4582A5DCC" modified="2023-09-13" version="1">MGTSSSRPLSPLTTTFPMPLYLCVDCGGTKTAAVISDASGNIVGRGSAGPSNITYLSVDGFIAAVKRAVGEALKQATAPKSSSVSLPLTDAAATPLAAAWFGISGADSPAAIMKVEKPLSTLLGIPVGPKLMIANDTHLLASPVRMHSDISYAVAVIAGTGSIAVSFRQDEDSKIIELGRVGGWGWILGDEGGGYDVGRETLRQLLMEQDRASVEGKPVVKGKLVENVLERFGVGEVMEILGGVYQGDPDSNVSVASSDVKALHNMSREKRISSLSPLVFEAGFEHGDPLALRILKTSARNLAEKIALLLGDGQLKDSKNVVNASESVVSFGGSLVGVEKYRQILLDDLAQKGHVFKHVVFVDDAAAAGAVGLAKTYNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED09</accession>
    <name>A0A9P6ED09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_908151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED09"/>
    <dbReference type="OrthoDB" id="2399539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="559" mass="60794" checksum="049933B15EDD87A8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED13</accession>
    <name>A0A9P6ED13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_857251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED13"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019413">
        <property type="term" value="P:acetate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000001">
        <property type="entry name" value="Mitochondrial aldehyde dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="500" mass="53927" checksum="F5C90015D204D53F" modified="2023-09-13" version="1">MPATFTYQFDTPLYKGTSSFSTGIFIDGKFVDGSNKTTIDVVNPTTGKVITSVSEGTEKDVDLAVEAAQKAFDTVWGLNTPGAQRGELLWKIAQALEKNAKELAALESLDNGKTFMWALGVDVKSAIDTFKYFAGWADKIHGKTIETTENKLAYTRHEPIGVVGQIIPWNFPLLMWSWKIAPALATGNTVVMKPSEFTPLSALRATAILHEAGVPNGVVNLVTGYGNTVGAAIASHMKIDKVAFTGSTLVGRKVMEAAAKSNLKNVTLELGGKSPNIIFDDADLEQAVNWAAHGIFWNHGQACCAGSRIFVQSGIYDKFLASFTEKAKAIKLGDPFGQGVDQGPQISQIQYDRIMGYIDSGKTDGATVHLGGERHGSEGYFINPTIFTDTKPDMKIVQEEIFGPVGVVIKFDDPADAIKQANDTSYGLASAVFTQDLNRAIETAHKLQAGTAWINCVNVIDVQVPFGGYKQSGIGRECGEYALSNYTNVKAVHINLGHKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDE6</accession>
    <name>A0A9P6EDE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide hydrolase</fullName>
            <ecNumber evidence="3">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_856862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDE6"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03880">
        <property type="entry name" value="M28_QC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000081">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037457">
        <property type="entry name" value="M28_QC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040234">
        <property type="entry name" value="QC/QCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283:SF6">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040535759" description="Peptide hydrolase" evidence="3">
        <location>
            <begin position="32"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="4">
        <location>
            <begin position="119"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="405" mass="45921" checksum="CA8DE95FC5D75EC5" modified="2023-09-13" version="1">MRLLPRAERLALCIFSLSWTASLFLPTCCHAAATEPRDLKTLSSTDAQSLINARDPLKGLDPSDPASHLSKILIPRPPDTENNTLVRNYIVSTLKALDWHVELDQFTGNTPYGAKHMANIIATKDPSAPRRLILSAHFDSKYFPNYPDNQFVGATDSAMSCAMMLDLAETLNTLLNKRKERYENGEEDDEEVADTTLQLVFFDGEEAFKDWTEVDSIYGARNLAEKWSTTYIPPTRKRHFINAQENELGAIEHLILLDLLGAANPRFRSYWLETAWLFDALADAERRLGESGAFAYGDEQSMASGKWKSWFRPRHAKDSNMGYIGDDHVPFLARGVPILHLISDPFPLVWHTLRDDGSALDRPTMRRWNILMRVFLSEYLNLQPNDLTSRDASDDPFSRNTSELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDT9</accession>
    <name>A0A9P6EDT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDT9"/>
    <dbReference type="OrthoDB" id="2499463at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8320" checksum="DFC82DBE3B70557D" modified="2023-09-13" version="1">MCRQPHFREAGLSANAVNGNTWDERLQEDLKNCRFQGTFASPKNVPITQRLLPISSATKLRDICTITSSTKRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEL9</accession>
    <name>A0A9P6EEL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_836028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEL9"/>
    <dbReference type="OrthoDB" id="3029306at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="468" mass="51381" checksum="FE1DDBD0AAC44002" modified="2023-09-13" version="1">MSKRAVIVDDTDPSIKYVGESWKADRGSRDSVGNYGSPFQSTLHGTDTSASLSFHFSGTSITVYGSNTVLNDSGVFDPQWECFIDNQNIGASYPYAIPENNWNFCGGSSLIDGPHTLTLNVSIKSQVFWFDRIEYNPSSTVSLENSNIRIEANDPDLQFGKDWKLGGDTNLTQTNGSAFNFEFTGVSISLFSYFLVAYPGTSTTGSYTIDGSSPQTFTLTGHPDDATTTAYDQKVFETLTLPMGRHNLSVVYHGNEDTTPLTFHYLVAENGTNSSTHGLTSTSAVLGPTSNIPAPTHAVHVPTKKSSIGAIVGGVVAGVGVIIITLVIIFLRRRRRSNENNVSARQFEPFQHRPYHQSSRHSSVPAYNSYIKPAEERTHILNTQDRGRINSNHIALSSRNLATRPPTYFSNQTLLNQSIFGKTPETPQRDSQHFRSGMDSIPPRVARHEDGRISPSEGTVDLPPRYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF49</accession>
    <name>A0A9P6EF49_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_836243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF49"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="77"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="681" mass="76472" checksum="64B91EA6499D9562" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFD8</accession>
    <name>A0A9P6EFD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_854303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFD8"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="308" mass="33413" checksum="10E71AB271D5B931" modified="2023-09-13" version="1">MAALIARSSTLNGVLRGSRHSVLLQNQPQFSQLHRAPAFRLMSSETQQPKYEYIVVSRPEPSVVLVTLNRPKALNALSSPLFEELNEALEQADRDDSVGAMVLTGSEKAFAAGADIKEMKDKQFADAYKNKFLEDWGNLSRLRKPLIAAVSGFALGGGCELALMCDIILASPTAKFGQPEINLAVTPGGGGSQRLVHAIGKSRTMEMVLTGRMVSAQEASDWGMVSRVVGEGEAEVVKEAVKMAKGISEKSQIAVQACKEVVNAAHELNLAEGLRFERRIFHGLFATNDQKEGMAAFAEKRKPNFTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG11</accession>
    <name>A0A9P6EG11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG11"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="41130" checksum="5BE360C5DE6A1521" modified="2023-09-13" version="1">MPSILSFQNATVQTSNGSTLTILNFDTPSAWLDPQTASYYELFRFLAVASLAIVLYDILQSLQDSYEIIFKKPHCFHKLVFVVSRLSCLACILVATLAHTLEISDCELMKYVGCALYTVAQAATGYLFYVRAMATPPRSKTIQIILLSTLMVLIGGSISAAFALRSVRIAPTRYCMTHVQHRGEYIVLGFVSQTIYDLLVCLFITKKLGPVRLPDSPIQKQSLRDTWFRSAKHYAQQCHHSQRFLQESQVYFLVALGLKIFASAWFYAFGGFNHSSGGLNIAFVFFDMVILNVLATNIYRKLILGKRGFTEPPLQTPHSPGSFVLNLMDPHSPINPDSKVDKDEPSTRPSRSPVKPGSCKNIEHTVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGH1</accession>
    <name>A0A9P6EGH1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial ribosomal protein L41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_854004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGH1"/>
    <dbReference type="OrthoDB" id="408933at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="151"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20467" checksum="B3C264819E18F559" modified="2023-09-13" version="1">MIPTAVRCSKASRAALTPKRAGKDFYKGTRQAFLPGGPRTGAPGRHVVRGKAKYRLMDDKVRVYVAPTLEDIVSTPLKPYVAIGKKLTLDQEIQLFGKFRGPKGITPEHFLRVAREHTYASANPDTPYRNPEPPSWMSAQKRLGIFASNATGLSVPGSNPVATSGGASKRNVTSPKPKVRELEVVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGK2</accession>
    <name>A0A9P6EGK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_869085</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGK2"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor SLU7" evidence="10">
        <location>
            <begin position="140"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="194"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="500"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9529178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="563" mass="62938" checksum="5C12BDAF8F63A033" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGN9</accession>
    <name>A0A9P6EGN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_854537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGN9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="42061" checksum="14A4F83B55423710" modified="2023-09-13" version="1" fragment="single">MTRSDRFRLAPSLDGEQLILIVCKTHWSNPSGIHTVVQALKILPFHAQSSIVPWMRFKLEGFGIKHCWMTSYHFAALLEYDRYLLVWDFQKDEVSMWDYFRSLIGESAGPPTWVHIFDDRLFTFHDSAVVEWEIPPFLPRSRWKDFLSMDPQPKPLNIMHDLEDDKLLALNTTDGAYSPLRILPSSAWNLWSDIPTYLAIFRTRNESPLLLFQFEQDNSSSQTISLRGRTFNQPQSTWIAYNFGKKYFSSPRVCDGSFVFSTCHNDGDVQLHLVPTDPSKQNGGSIKINRLALRGPNIFQSVACPATGRMCVSVFKETQNEIIILEFLDTPIHVQMISWFNAVIWVLRDICNWLYDIGLKRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGY4</accession>
    <name>A0A9P6EGY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGY4"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="54427" checksum="86357BA2F9D71DF0" modified="2023-09-13" version="1">MVADVSSPPLDAGSDFGAVGNHRRPLNFTTALPFELSAKIFLHCLPALPSLEIFEHCDLSKILPTLLALSSVCQAWRLIAWSTPELWTTLLIECKGFQLKPDLSFVKKSLHRSGNFPLAIRFGFDQSTRISDFGSTIHDVVKLICTHAHRWTVLQLSAPFSVISLMKASEDCHPVNLSCLIIHSFPDMEIGYSSTSTKPPIFSLGQSILPSPSRLSIHHIKCQNIHIDFSQLRHFYAGVITPLEFTNILRLVPRMASLSCTLSDYGIDNTQSLGPANTEMVYSQHMKSLKLGFNDTEVIVLDFLTFPSLEHFECCKLDFESLKRFFLRSGSRLTRLLLNQDVSNRKLVELLYLAPILRELTIEYCALQAEFFQHLWETATQKNDEAAFLSHLRVIHYTMVNMVHPGLFQWSNLSTWRIDPRGSAAWTRPLHRLTFKSTAQKDFEINFAAGDRAEILRLVESGLDVRILDRDGVDVLTSRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH79</accession>
    <name>A0A9P6EH79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_853845</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH79"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="78"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="349"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="602"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="706"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="602"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9528853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="730" mass="79473" checksum="95E0EF0FC5BBA77E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHE1</accession>
    <name>A0A9P6EHE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_835399</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHE1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="505" mass="57899" checksum="560E2BCBE298D48B" modified="2023-09-13" version="1">MLDHQLTAVGFVTVAYFLTLSFFTGRTRKLRHIPTAGFSLPILCLFSAARYVFNARKVIDEALVKRPTSIFKIPFLLEWVVIVHQPVHIEEMRKMPENVLSSLKALDYVFQIAYTLGPHINEDPYHIPIARAQLTRSLPLLVPELHDELVQALKQNIPPTTDWSEVKALDTMMKIISRTSNRAFVGAPLCRNPEWIDLNVQYTLDVIKVASVLRFLPPFIRPFMNKLISQVGKRTDKALELLRPVIRERRTEREQKGENHPDKPLGKVDALSWLMDEAKGKEAEEWYLSSRILTINFAAIHTSSMTFTHALYNIAAYQEYVHPLREEVEEVISREGWTKAALDQMPRIDSFLKESQRLTPMALNLMGRIAMQDYTFSDGTTIPAGTMMAVYVVNDHTSEEFYENPLKFDGFRFVKRREHAVTSGQTEKRFDFVTTGLDSLGFGHGRHACPGRYFASSELKLMLAYIVMNYDVRTVEQGVRPEDLYIIDNCIPNPTAKLLFRCRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHR7</accession>
    <name>A0A9P6EHR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_289624</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHR7"/>
    <dbReference type="OrthoDB" id="3496539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="16">
        <location>
            <begin position="2"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9528924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="18970" checksum="39132E08B651A994" modified="2023-09-13" version="1">MMRCNNVTVNATETITVKPGQLVGLAVNASQSAIPSIYHTGPAALYLSKAAGLAQDYVGDGDWIKFASWGPTYNPFNFTCTNATELTALLPNIPSGEYLLRAEHSAVHDINSPQFFIGCAQIKVENPGTPVDLPAGVKIPGYVTGKEPSFVFNISAPDITYYPMPAPPVADLPVVVYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI32</accession>
    <name>A0A9P6EI32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Splicing factor U2AF 26 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_852538</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI32"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000066">
        <property type="entry name" value="Splicing factor u2af 23 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="26253" checksum="0D6BEE79C29EC08A" modified="2023-09-13" version="1">MASHLANIFGTEQDRVNCSFYYKIGACRHGDRCSRKHIRPPFSQTILLPNVYHNPAHDPVCKVTDKELQEGFDAVYEDLYCELSKFGHLLELHVCDNVGDHLIGNVYARYEWETEAQSAVDSCNERWYAGRPLYAELSPVTDFREACCRQNENGECNRGGFCNFMHLRLASPDLVKQLHHGQRLDRKLNPQKATQGAGGWEPPKREGGKGRSASPSRRGGNTGEDRWTRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI92</accession>
    <name>A0A9P6EI92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_893400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI92"/>
    <dbReference type="OrthoDB" id="420606at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF314">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="12"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="473" mass="52988" checksum="214A7E310BC37AFF" modified="2023-09-13" version="1">MDEEAGVSLKFVVVGAGLAGLAAAYTLARAGHHVLVLEHFEEHIRSLGCVGASPSMTRILIQWGLKENIERLFQSCDKCQFFDATTGSSLGALSLHLMAEIKSEGSAGFMIAPHYDLVDMFLELGTRAGVQYRFGVDATGLDPQTDNVLLSTGEVISADVIIAGDGSHSVFRQYVEEDRFSDDEDLASLIPPKFAHVMAPISIEDIRKDKDLDTLCELNSWDYWLGDGYICHCSFSNHGKNGLIAIVVPYEGEAKPEHAEWTFCTDYKAYGVDLSKLEQRLRKLFQTANFFYGKIYENRPLETIHAISQKVILVGEAAHSILPGSYHYPALAFEDAQTLGSLFSKIQKKDQISKFLASYEEIRQPRLKFVYESEMAYRIRLTSPDETIRRHRNELLRRLSEYNMNSSSADEEVLMEGWGTDFEIMSYDTNEQVTDWWRKYGISIVGTSQDACGEKELKIGVATQVAAQFVDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI99</accession>
    <name>A0A9P6EI99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cation efflux family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_764853</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI99"/>
    <dbReference type="OrthoDB" id="435980at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF15">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="56"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="346"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="414" mass="44949" checksum="6194FB8A402170EF" modified="2023-09-13" version="1">MTNSTAHEHDQHEHEHSHSHSLFGHSHSHGEEHTHDAEQILAALKGSGDRGSYITLVGLFTNVALTLAKGLAGWFMHSASLMADAGHSMSDLLGDFVTLFCWRLSRKPPSEKYPYGFAKFETFGTSTISILLIGGALGIGFHSYHLLMTALTETAGSLPPGPTHDILRFITSTATLPDISLGHSHGHGHDHGSAQLVDVNAAWFAAASVLIKEWLYRITKVVADEEKSPVLLANAIHHRSDAYSSLVAFFAILGSWFFPALPLDPLGGLLVSAVIFRQGYGLFAETLGDLTDAGVSPRTKQALLKALTPFTESQSNGSTSHTHNHNHDDPHSNHNGLSHPLPPIFVSDLRARRAGSLLFVDLTARIPGTITVSQASSLEEQIEHTLKTARKEIKEVRITFKPLIDSVPPLKELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EII9</accession>
    <name>A0A9P6EII9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_882744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EII9"/>
    <dbReference type="OrthoDB" id="7474005at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="383" mass="40616" checksum="B0229DEB484DD5FF" modified="2023-09-13" version="1" fragment="single">MQPSTNPEHSILSFGHNETVPSPSSQPFILQFGDSTQMDCRLGGSSLLDDDDLAASGPLLFGDNNVKMSPPSPRGIQAGDDDPMDNSFMTSGRSSILPPHHLSNPSESLDFGEPKGDAESSAALDFGPPFTQLPQANFGSSPSKLLSFGQPGGDVELSSSETLDFGPPLTQQSEANLGSIMSKLLDFGELIVDVQSSPSEPLDFGPPLTQQPEAIQRPGLTQQPEATQQPEVTQRGEVDIGRGTSDLLDLGEFEVDVQSTPSELLDFGPPLAQRPEEIQRPEATRKPEATQQPEVDSGRGTSNFLAFGEFDADIQSAGILDFGPPLTQRSEANFGSSTSKLLDFGQLGGDVALSSSETLDFGPPLTQRPKVDIGPGASDFLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIK8</accession>
    <name>A0A9P6EIK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIK8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="67" mass="8027" checksum="BF53CDE4EB71F1A6" modified="2023-09-13" version="1">MGIIEYSQVFTFFSKSIALFVILFFSSLTWVMRRKIHILYHPLILRHCFNHPKEGYCRCDPLNGYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIP4</accession>
    <name>A0A9P6EIP4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_852583</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIP4"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF82">
        <property type="entry name" value="NIPA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="411"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="466"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="59740" checksum="7D6BF754019D013E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIS8</accession>
    <name>A0A9P6EIS8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_851744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIS8"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040531984" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="30"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="557" mass="60023" checksum="229A9BB2D97E44BF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIY6</accession>
    <name>A0A9P6EIY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIY6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="171" mass="17600" checksum="9E06C021D64BDB42" modified="2023-09-13" version="1" fragment="single">MPPKATPTAATANVAKKKAATAAKTSAAGSTTKSAVPSASKPAAPDASKTSTPGGKVSLDELKRRQVEAQRNKEALNRKAEEDRVARETEMLRLAAETAKAEKEKQDAEEAERQLEAEIAAATAAAEAEAEAEAEAEAAAAEGDDEDLPKLPPSKAKRGGASKRKGKGKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKM3</accession>
    <name>A0A9P6EKM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_850414</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKM3"/>
    <dbReference type="OrthoDB" id="10255539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03273">
        <property type="entry name" value="ABC_SMC2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000278">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000385">
        <property type="entry name" value="Structural maintenance of chromosomes 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027120">
        <property type="entry name" value="Smc2_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="526"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1182"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="267"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="405"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="688"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="966"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9530835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1205" mass="136414" checksum="8F7A91486DA2F7A6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKV6</accession>
    <name>A0A9P6EKV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKV6"/>
    <dbReference type="OrthoDB" id="3023920at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="11421" checksum="0E15330EFEC0C2AF" modified="2023-09-13" version="1">MFYAGSVGSTVMTAGIPGARHYVQAAPMSAVMPGQHYYPAMHSAPVGYPMTAAPTMMYNSPQYAHASPYGYYGGQPTVIVSSPPSRRHRSRSRPRHGHSSGFLGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELB5</accession>
    <name>A0A9P6ELB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_787293</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays an important role in cellulose degradation. Shows hydrolytic activity against several glycosidic compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELB5"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080079">
        <property type="term" value="F:cellobiose glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000011">
        <property type="entry name" value="Cytosolic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9531231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="547" mass="61951" checksum="7CC8BCAD883D68A0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELJ5</accession>
    <name>A0A9P6ELJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_98969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELJ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="177" mass="19993" checksum="3CAED25BF5DE8751" modified="2023-09-13" version="1">MMLSITVSTQRSRFRNNTFRISQPTIPVLYDVIRRTKSSITFRLIVISASLQVLPILLRRGTPNLPRHRVGSASIDGRKRRSYCLNQTTAMPSILPNQSILDTMPYEMHIKAEKQEVGNILTGQDGTATDTRAVSYLNRDPFPLNDMFNFPSECFLGGGEGHIEDNQLSDWSFFVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMG2</accession>
    <name>A0A9P6EMG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidylserine decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.65</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_848668</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism; phosphatidylethanolamine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="3"/>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMG2"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF17">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="43661" checksum="2186A92EC02EA6AB" modified="2023-09-13" version="1">MSSLHPNNIDKPIETVHPSNTPRAKQDDVVEGLSTVVEHSAWNPNLKATIHAPMHVLAHESFTWLHKLVPGIEKLAVEHHVGNYVAMRGGGEPFFESMPLYARLGMHLLFYGKEEVKLLGNRRIEDVLKEQSVKQGRIFDEAKSAESIGAFIETYSIQTSELAEPDTSKYANFNEFFSRKLKAGARPIQFEEDKSVICSAADSRLTVYQSTDLAKKFWVKGTNFTIPHLLNLNSSDPKLASFDNASLAIFRLAPADYHRFHSPIAGEVQDILHIPGQYYTVNPQAVNEPGFDVFTANTRSVLYMKETTTGLPIAFVAIGALLVGSIKWTGGKQPGTKVERGDELGYFAYGGSTVVVVFPKELIKFDDDLVANSEKPIETLVKVGYSLGRIPVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMQ7</accession>
    <name>A0A9P6EMQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_848129</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMQ7"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000132">
        <property type="entry name" value="Aspartyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="238"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9531975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="546" mass="61823" checksum="62D709960D2F6099" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENC7</accession>
    <name>A0A9P6ENC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_847514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENC7"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="201"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="94"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="34379" checksum="028AD8A42B354C15" modified="2023-09-13" version="1">MAYRDRLAASRAQRQQQPVELSNLEQPQNPSYTTSPTNPANSSDTPAFLAEDSAIQQGIQQLRNNVARLAALRLQSVNAIDETHATQEEIDTLTNETRGLSQDLKNRIQQLESQPMRQDVQLRKNRITLLRNKFVEALQEYQREEQEGRQRSRQRVERQLKIVKPDATPQEVAAAVEGGGQQIFAQALSSSTRYGESRSAYREVQERQQELRRVEQTLAELAQLFQDMAAMVERDDQLIDNIHDTVQKVNTDTEAAAQQTEIAVKHARSYRKGRWICFGITFTICAVIALAVGLYFGVGPGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6END1</accession>
    <name>A0A9P6END1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6END1"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF95">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="147" mass="16241" checksum="666E76A543ECF46D" modified="2023-09-13" version="1">MTLTGPFKVLEVGAGTGIFTRALLADEGWNASIRRLTAVEPSKGMRDLLCQKVRDPRVDVADGIFQSTQIAEKWADVILIAQAYHWCTDFNAATVEFARVLKPGGIVALTWNSEDRLGADWVSQIWKVLGNHEEGTPVREQTVAPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENL7</accession>
    <name>A0A9P6ENL7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GTP-binding protein lepa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_847314</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENL7"/>
    <dbReference type="OrthoDB" id="1074at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000078">
        <property type="entry name" value="Elongation factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="53"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="130"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="657" mass="73149" checksum="21A2149E6A8E51AD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENZ5</accession>
    <name>A0A9P6ENZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="5">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_846142</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENZ5"/>
    <dbReference type="OrthoDB" id="1735853at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12240:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit B, brain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="8">
        <location>
            <begin position="34"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="7">
        <location>
            <begin position="157"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="9">
        <location>
            <begin position="390"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9533258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="517" mass="57239" checksum="A4C0247E51150996" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPQ4</accession>
    <name>A0A9P6EPQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_756621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPQ4"/>
    <dbReference type="OrthoDB" id="109543at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23802">
        <property type="entry name" value="UBCc_UBE2Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051838">
        <property type="entry name" value="ARTD_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21328">
        <property type="entry name" value="POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="949"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1130" mass="125635" checksum="CFA90649EFD2EA1F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ13</accession>
    <name>A0A9P6EQ13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_846728</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCNDBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ13"/>
    <dbReference type="OrthoDB" id="41588at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049318">
        <property type="entry name" value="GCIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20936">
        <property type="entry name" value="GCIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="7">
        <location>
            <begin position="48"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like C-terminal" evidence="8">
        <location>
            <begin position="202"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="357" mass="38968" checksum="AB7DF7728D07143E" modified="2023-09-13" version="1">MSESQKALSALNLLLDNCRIGLTALVDGSLPDNDQLNASFSTIRTDFGSILSLLYSSATKVALALKPAPSPQYKAALVPLQDLSNNTAALVHSVRLMRQSQGATLVLEYEGLSKNILVAIQAFANGLSQSNLGSHEETFIAVGKLHELIDNAKKPNVLSSDNRAAVRRRWVQDYESLVDGWEELQDIDKTSDMEDGDEDEFDDGWDELGSKQTFAPSELERIEKVRALVKVANLLHTRVVKDLLSSNTHKQDNVTLDNLATYSAQLLSASDELISSMYTPQQPTAISLHLSSYLGALKAIQHALNPKNEDLEQQLSALSVSNASLSKKTKWLKTCFDLIDKAGAQVSETLVAVKESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ49</accession>
    <name>A0A9P6EQ49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_844891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ49"/>
    <dbReference type="OrthoDB" id="2834207at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="8903" checksum="66ACCB5D597DCF2D" modified="2023-09-13" version="1">MPGRKEPADWKIIETSPSGLELTFYNTKTEESTFYIPDGFTATDVLNVPGAKKYWHNVADVTKYMKQMEVEKAQDQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQF3</accession>
    <name>A0A9P6EQF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-NAD kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQF3"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="11"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="395" mass="43002" checksum="B223AA8A6A9831F4" modified="2023-09-13" version="1">MLLIPHSIGVKRSRSFLVFVNPFGGTKQGAAIFTNKVYPLFKASGCELEVIHTTRQGHGLEVAKTLRLDHYDAIVTVSGDGLIHEVLNGLAQHAEAAHALATPVVPIPTGSGNGLSLNLLGIEEGFDVAAAALGAIKGRHMKVDLFSFVQGGQRSISFMSQSLGLMADVDIGTDHLRWMGDTRFMVGLIKGIAQYKRCPVKLSYKLAEQDKHKMAEAVHSRTKELAKLGRTPLASPSNSGSEVSFHDGPTAGLPPLQYLKEDEDGWVTFDEPILYVYAGKGPYVGRDFMAFPVSLPDDGLIDICVMPAGSRLDIIGGLDGAEKGAAFWNQKLLYVKAYAYRIQPTKKQQGYLSVDGEQFPFEDFQVEVHRGLGTTLSMYGHYVAPFEPRARPTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQN4</accession>
    <name>A0A9P6EQN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_781727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQN4"/>
    <dbReference type="OrthoDB" id="3065354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="303" mass="35696" checksum="8FEA8628A66EC5B9" modified="2023-09-13" version="1">MRPHNRNKRSRNNKDHDGDVYMNVQEDHRSDTYARSHGSVDNYRAASTSSRTNYIPERERSTHSHHDEDWHRAAYDHERYPYAEPYPRGDRLDDYDNGHSGGGGWGTIDPPAYSSSRHEWPHPYEHGGAPAYPDPSSWEAPVVDYSGGRNAYVGRWPERETRDIPVDDWVAPTTRNEHGHDRRSDWQQESRRDKNSSQGFQSDSGWGHRRREREWSRETSSQQDYSESRPSVEERQWEPAESWKSSNRTSQQQPSNQQNQQHVQRQNGQRSNGKSKRNRDQNKQRREWRQVDDGDLNKSVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER87</accession>
    <name>A0A9P6ER87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_846071</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER87"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9533214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="542" mass="62015" checksum="9C6B55C7D7346A2F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERF0</accession>
    <name>A0A9P6ERF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_757480</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERF0"/>
    <dbReference type="OrthoDB" id="255819at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="120" mass="13504" checksum="2F01FBA492382D5D" modified="2023-09-13" version="1">MPTLNFVTNIELPDRKAFALEFSKFGAKLLGKPEGYISVLVTYNDTLTFAGTFDPAFSLRIDSLDNINPTINEVYSQEFTKFFKEKLGIPNDRGYITFIDPGRANIAFQGTTFETIFGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERF2</accession>
    <name>A0A9P6ERF2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERF2"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040533846" description="Hydrophobin" evidence="6">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="10774" checksum="170AA43C6E6D7ABA" modified="2023-09-13" version="1">MFSKLVVIFVASVASFVAAAPGGISNSCDTGPVQCCDSLYKSDSAEFNVIKQLVGANVPIGALVGSQCSPLSIIGVGGGSSCKSEPVCCDDNKFGGLVAVGCSPVGVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERG1</accession>
    <name>A0A9P6ERG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERG1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="80" mass="9291" checksum="2F487C92698C3912" modified="2023-09-13" version="1">MKQPNLLLSEAITFFGWVSTYTNAWNGLSQGFIWILRKLYILRNSIDREDEEELESTPEMYSPADLGPLFGEAQVHELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESR2</accession>
    <name>A0A9P6ESR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_320860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESR2"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="17754" checksum="52DAE0A907BA2746" modified="2023-09-13" version="1">MQNTNLGPLGADATESLEWRNHQRDASEELHDAELHILEPVLSDDEEEFVYPSEPSSVGVASAPAPTRVSEPSPAQLESLFAAASSGDLPLLKRLFKKAVENGEVEAFALANYASTRTGFTALHAAASRGYYDIAVWRMFSSLLYMQRLTIVCSDRGMWGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUQ9</accession>
    <name>A0A9P6EUQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_830680</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Lipid-anchor</topology>
            <topology evidence="10">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUQ9"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012946">
        <property type="entry name" value="X8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF2">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07983">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00768">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040538246" description="1,3-beta-glucanosyltransferase" evidence="10">
        <location>
            <begin position="27"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="X8" evidence="12">
        <location>
            <begin position="395"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="508"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9535746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="58252" checksum="2BD5680110649D6F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUU1</accession>
    <name>A0A9P6EUU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_878814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUU1"/>
    <dbReference type="OrthoDB" id="9450131at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="399" mass="43555" checksum="B55FB9CC3D545D5E" modified="2023-09-13" version="1">MPLRVMNSFPSRVKSAQTVPKALPPSRSGSASSSDTAAHQPGSPASLRSNTSSEDGTLLTQHSAFGSKEDTLPRYSDDKNIYTRYLEKEKQRISHEFDPYEAVNVQQNLHQASSSSSRRLVSRTGQQLAGAIGPDNAPHSMEIDSIPCAGVRIRHGPLTGLLAWRLVVRVPEGQTCNWWETKALKRRRRISLAPAALLPPPPHKPVHSHSYSEWNAPNGNQLKDILRDSSASLSSSSLPLPKFPILPRHKSHDSAPTPPPKTTSLVANFILDTSLPHSLISRETLLTLGYPISQLPPSLDPNQTYDESDDPPTVTLSIQGISTRLQIANPGESSRLGVQFLQDAGVSVFFPKDGDGVGPVLYQESVRTMQDIPTTLPNGARGNRLSLQQRVRNLFGMTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUW3</accession>
    <name>A0A9P6EUW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_754291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUW3"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000016">
        <property type="entry name" value="Polyubiquitin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000014">
        <property type="entry name" value="Ubiquitin-60S ribosomal L40 fusion"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="229"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="34238" checksum="ADF7B4F656A28C3C" modified="2023-09-13" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVP5</accession>
    <name>A0A9P6EVP5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVP5"/>
    <dbReference type="OrthoDB" id="3358646at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="445"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="760" mass="81598" checksum="6502560CFA1FDB80" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI95</accession>
    <name>A0A9P6JI95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_800952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI95"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038921">
        <property type="entry name" value="YOR389W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204:SF1">
        <property type="entry name" value="ENTEROTOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35204">
        <property type="entry name" value="YALI0A21131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040217850" evidence="2">
        <location>
            <begin position="28"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="588" mass="67939" checksum="FEB2CAEE7828E153" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIC3</accession>
    <name>A0A9P6JIC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIC3"/>
    <dbReference type="OrthoDB" id="3107538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="460" mass="50327" checksum="9AA911D0D6F46C80" modified="2023-09-13" version="1">MGSFFSSFGVFSLSPNDIGLVVYATINTKILNVTSVRVHPAGSLVTIGNEYGSIALYRVDDANPLCHRFSLSYKYGGVSEICWTGHEYVVVGTTRGRLIVFKLEGDGRRLYEVSHVVAHGDGAAQIDVNSIAYNSRTKFLASVGEGKKSVRLWEQAEDGSLKEKLQPLSTTAFSAARYVTFFREGHQLLVAFLEHPLIQIFTLEPFALSQELQLEFEGSDQKINTFLLIFWASGNALILEGFGKLAIYSLTSGCNFFDSTTMAPAQGQPLIPKQFVIQECSQALAALRDGAYVASVSGPLLITIIRTTDGKYCGNLKSRGQQDLLIAASITDDGSSTLTIWLNKRRLIVTDDQQHDHSNLKIVMLCIAISLLFQVSASFFSFRDINQYFYGSAEVDNQDAHTHQDRILSSDSTNRCNVEVGITSSKDVVITPAPTALVGVVSSLNLQTSEESLCTLAARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIQ0</accession>
    <name>A0A9P6JIQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_777341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157953">
        <property type="protein sequence ID" value="KAF9522260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIQ0"/>
    <dbReference type="OrthoDB" id="3268424at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="1">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="8445" checksum="7B4632AC3E9604DF" modified="2023-09-13" version="1">MGSDLCSAPATSVDAERAFSAGRRQVNFLQHNKSSQTFKAQMALGSWARSPLYPGIESVSQMVQGRMGREDDDFFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJQ1</accession>
    <name>A0A9P6JJQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_689133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJQ1"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000031">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="28421" checksum="AC4B421D4A156FC5" modified="2023-09-13" version="1">MARRYDSRTTIFSPEGRLYQIEYAMEAISHAGTVLGVLATDGVVLAAEKKVTGKLLDLSSAKDGGYGGSGEKLYLLNSNVIGGVAGLTADANSLVNFARSAAQRHLLTYNEDIPVELLAQRLCDMKQGYTQFGGLRPFGVSLLYAGYDPHYQFQLYHSDPSGNYSGWKATCIGANNGTAQSLLKQEYKDDIGVKEAIGLVLRTMSKTMDSTTLGSEKLEFAVLTVDPETNKPKAKIYRPAEIDALLLSEGLTKKEDDAEMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM72</accession>
    <name>A0A9P6JM72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Phosphatidylinositol transfer protein SFH5</fullName>
            <shortName evidence="15">PITP SFH5</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_796534</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)</text>
            <dbReference type="Rhea" id="RHEA:38691"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:38692"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 15">Endoplasmic reticulum membrane</location>
            <topology evidence="2 15">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Microsome membrane</location>
            <topology evidence="15">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the SFH5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM72"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017157">
        <property type="term" value="P:regulation of exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042938">
        <property type="entry name" value="Sfh5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0492">Microsome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="17">
        <location>
            <begin position="120"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9525364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="32374" checksum="7B2242BB8D62864A" modified="2023-09-13" version="1">MSATETAAPAPQPGQAEATVPVVEEPQNPLTQKFTEAEWKSLKEFRIQLPDIFAEAYPDNPEAKETPISLWGVDIDPTNPVGDARVSVVLLKFLRARHLNVSEGRSMLVNTLRWRESFDLKAACAEEFPKDVFGGLGKVYGRDKGGRPVVYNIYGGTQDLKAAFGDVQRFIRWRVALMEQSVSQLDFINVDQTLQIHDYEGVSITSRDANSKAAASEATNIFQSHYPELLYHKLFVNVPTLLTWIFWAFKPLISAETVKKMEVVGTGKGTVRRALAVWIDEGEVEGRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMA1</accession>
    <name>A0A9P6JMA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">APC amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_859593</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMA1"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF498">
        <property type="entry name" value="HIGH-AFFINITY METHIONINE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="560" mass="61976" checksum="85E66B7E27099B94" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN44</accession>
    <name>A0A9P6JN44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">18S rRNA factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_770517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN44"/>
    <dbReference type="OrthoDB" id="287393at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9526310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="232" mass="26621" checksum="36F3ECDEE15F09FC" modified="2023-09-13" version="1">MDRGGFIQDDSLKPLTKESLAAFNAAQERAGVVYISRIPPGMQPAKVRHLMSAYGEVGRVYLQQEDAKRAYLRRKFTSTKKAHYTEGWVEFKDKKIARSAAGMLNAQPIGGKKGTRWRDDIWTMKYLPKFKWYMLTEQVAHEAALHKAKLQVELSQSKNEQQQYLKNVELAKVLAKRAAKKKEKGEEFELKPNPQQKKRILEVSEENKARKKSKKDPPSDNVDLNNVLSSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN71</accession>
    <name>A0A9P6JN71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN71"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040435721" evidence="1">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="10298" checksum="D2117C6CAACE2443" modified="2023-09-13" version="1" fragment="single">MPQRNSCILPVCSGLTLLKLLEALKWKLDHHRDLNLKSTNNSQNQPRGHKRAMICLNIQEYTTFLNFTHQIVAEMARNEILSHQSIAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNL5</accession>
    <name>A0A9P6JNL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNL5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="19888" checksum="1987B2502A9DB91A" modified="2023-09-13" version="1">MPAKRRRADSVPYDEEQELTSSQESGEADTAMRTILEALRKQTTKRPQDDKKFLQKMRNSLIEELQSETTELLESKDRCEKLFTAATIEYAKIEDSIHKEWVNLENRSILSEKLHRDLEVLEVKASKTHSETRDGGLNKMLHACQAMASAVDKVDMNEAKREGKHEQGETGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNN7</accession>
    <name>A0A9P6JNN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNN7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="254" mass="28090" checksum="2164270F86266E33" modified="2023-09-13" version="1">MISIAGLKSGIASHPVFVSLAQISTVEAVDYSACTVTTMTSFPLEILDHILSLLKKDKTTLILCFKASPLLGAVAERYLYEHISLEMITKPLEQKLQAFLSSHPRASCYVKSITVLFPDSKISQHQAATKRLTETSISWSEIQGIQRETWLKIACLPTLKNLVLRGISDFPFVVLDRCRNLKQVDLLGDIEYKIESPEEAPVLSSAGDQRHLTILNPCFAIRDVSGGLASRIKESAKDALVDAPSISRLSWYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNR5</accession>
    <name>A0A9P6JNR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_884084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNR5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="260" mass="29967" checksum="605759E37827A9BD" modified="2023-09-13" version="1">MLLKHCRFTINPGRKLPELQVGDDYYYLAIVQAQLTRRNLACQRGPIRPNELFVWRYVRVASRTLKLRKSRVHSFKLYSSNLVSPRIMASYCFVFPEMIPLEEKPQPRGQPDKSCLNLRTPLYSYGWIIPQREVLNYVEKALASKMTIGPTNIEGAFKSRYLNPRWREMGFESLFKNQDLDQPKTMRIGKSLVLIVISSNATSKRIEAVHGNREYISACQKCIGPIVDAISTDPVWFRAGVNGCPEGYTQYDLGDDDFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQA5</accession>
    <name>A0A9P6JQA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQA5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="84" mass="9239" checksum="302132C7EB872D52" modified="2023-09-13" version="1">MKYSDFLPNARILTVHSNLINSSTDLSFSCPNSTLNTVGPNNVFLSIFHHCFAVMGIFAYHLPKSTQQKTVSAAQHGRGLMKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQL5</accession>
    <name>A0A9P6JQL5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS5m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">28S ribosomal protein S5, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_813635</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQL5"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000022">
        <property type="entry name" value="28S ribosomal protein S5, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000002">
        <property type="entry name" value="30S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="333"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9528695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="512" mass="56928" checksum="26CF7EF49CABBD9F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRA5</accession>
    <name>A0A9P6JRA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRA5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="78" mass="9317" checksum="D1840EE1D84C18A0" modified="2023-09-13" version="1">MNETLASRFMFVVVFGVEKRGRQIKEERRGRETQIKEERRGRETQIKEEKREEKDDANEENGNRANEYEMVVGVEKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRL1</accession>
    <name>A0A9P6JRL1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PhyH-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_809836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRL1"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF48">
        <property type="entry name" value="ECTOINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="30158" checksum="D02EE657C26BD4BE" modified="2023-09-13" version="1">MMPSNTPLTDEQLASFSKNGYLILRDVLSTQETTALQRWAQEIHDLPCTEHSSWMPYDEIQPNGTRVLCRTENFADSHTGFGALLRGETFLRILNQLSGEEMILFKEKINYKLAGSGGYSAHIDSTAYTHIKNVKHLTILLAIDAADTSNGGLEVVEGSHLMSIPISDVDRCIESSWVDGQTWVPVELKPGEMLIFGSYLAHRSDANASNGARKAVYATYNCKREGDLREQYYADRRVVWPATHMRKAGKSYQLGRMRYGFGSPMLTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRQ7</accession>
    <name>A0A9P6JRQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hsp70 family chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_868945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRQ7"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="58824" checksum="1CCB0B6CEC91F263" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRW1</accession>
    <name>A0A9P6JRW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="24">Carbamoyl-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CPB83DRAFT_881920</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the 2nd section; belongs to the CarB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the N-terminal section; belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1370:FF:000002">
        <property type="entry name" value="Aspartate carbamoyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1370:FF:000005">
        <property type="entry name" value="CAD protein-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000005">
        <property type="entry name" value="CAD protein-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000011">
        <property type="entry name" value="CAD protein-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000004">
        <property type="entry name" value="Carbamoyl-phosphate synthase (glutamine-hydrolyzing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
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    </dbReference>
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        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
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    </dbReference>
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        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
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    </dbReference>
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        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
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    </dbReference>
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        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
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        <property type="match status" value="2"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
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        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CPSase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
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        <property type="entry name" value="MGS-like_dom"/>
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        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002032">
        <property type="entry name" value="PRK00856.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRK12815.1"/>
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    </dbReference>
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        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF5">
        <property type="entry name" value="CAD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00101">
        <property type="entry name" value="ATCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="22">
        <location>
            <begin position="606"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="22">
        <location>
            <begin position="1141"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="23">
        <location>
            <begin position="1397"/>
            <end position="1578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00043998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF9530656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2230" mass="244139" checksum="A3D5394B028E48CC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT35</accession>
    <name>A0A9P6JT35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_785717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10255344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="284"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="564"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="658"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="777"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1278"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1305"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1315"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1408"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1425"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1439"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1457"/>
            <end position="1466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1493" mass="168692" checksum="217D642EDA66E311" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTM9</accession>
    <name>A0A9P6JTM9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_56457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTM9"/>
    <dbReference type="OrthoDB" id="3233180at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="537" mass="60409" checksum="E175F49427E0E6EA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU17</accession>
    <name>A0A9P6JU17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_406199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU17"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF14">
        <property type="entry name" value="ASL1-LIKE GLYCOSYL HYDROLASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040183691" description="Asl1-like glycosyl hydrolase catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="46"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="280" mass="30808" checksum="0FCBF37FA280C21D" modified="2023-09-13" version="1">MPSCYHSQIKFLFAALVCSLSIVSAAPSTIYAKFIPNSVKAGISAGDAFDAVKDHIGWWYDWTPAPRYHTGKPVAVSMLWGDGTADRQDADRLATFKKLTTVPQFLLGFEEPDCASGHGSAGMTVQQGVDAWEKYIAPMKAKGALLGSPSMCKQADETWLAEFKAKIKTPWDFTAIHINKQDLEGVKRDIKHYKDTYGLPIWVTELACVNDVNGFAPCTDQSIINNFIDTVVPYLQSNADVTAYAYSNGQELGDVWPMTKSDGSLSESGKRYISVISKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV43</accession>
    <name>A0A9P6JV43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_843328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV43"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000808">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="367" mass="41053" checksum="EDB639616DC897BA" modified="2023-09-13" version="1">MGEYPKLDPYSRSRYDHGVDSKIVIMGNSGVGKTSLLYRYTQNRFEPKNNTATSGAFFVTKKVHVNGVKVRLQLWDTAGQERFRSMAPMYYRGANAALLLYDITNASTFDDIRGWLEELKKNCPPELIIYIVGSKADLHHHRQVTPDLARLSLHNWFPPPRPPTPPPPPQPSTLSYIRPRFTSLPGLLSPTFGNSTNPSTPSPSSPDAPEYLDLPSGRPSALQRRVSAQSKPKTASSLTRSNSSNGTKTPQSSRFGPRYNGYNDNVDNSSNSIEEVDEDTDDDTEWGLSKGMELFEVSAKDDTGISHLFEHLISAIILRKDVIERENDLKKRDSVFLDSMSTPSWSNPPPDELESEKPSRFGSWNCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVA2</accession>
    <name>A0A9P6JVA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVA2"/>
    <dbReference type="OrthoDB" id="2797886at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="640" mass="70072" checksum="6D639D110C7050E3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVE8</accession>
    <name>A0A9P6JVE8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Mediator complex subunit 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_889414</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the SRB8-11 complex, which itself associates with the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="103819at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009401">
        <property type="entry name" value="Med13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051139">
        <property type="entry name" value="Mediator_complx_sub13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021643">
        <property type="entry name" value="Mediator_Med13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06333">
        <property type="entry name" value="Med13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11597">
        <property type="entry name" value="Med13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med13 N-terminal" evidence="13">
        <location>
            <begin position="10"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit Med13 C-terminal" evidence="12">
        <location>
            <begin position="1220"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="325"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="397"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="667"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="832"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="413"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="833"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9534436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1590" mass="174540" checksum="3CA1C59C262B3696" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWA6</accession>
    <name>A0A9P6JWA6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_841676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWA6"/>
    <dbReference type="OrthoDB" id="2591431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040124661" evidence="3">
        <location>
            <begin position="30"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="53763" checksum="840133B8EA73E53C" modified="2023-09-13" version="1">MRGDLLFLSWRTAILFALAINHLAVSASAFSFSYTTPTQCDDVTVNWQGGQPPFTLLVIPPSQTMQNFSIPSSNFNNNAGSFTTQLILGENTRVMFAMSDATGVTAGGISPLLSVGSSTSGATCNTTVRMPDFFFSLNGDLKECMPYTFSQYSGAILPIRVMGFIPSGPFFSSSAPDQSDTYVWKNTYPAGTPISFTVVDSQGRSGGTSNIRTVMASGDTSCKSQSVIFTTSSPTDTASSSSTTNNSSDDRATGIIGAAMIAGIVILILGFVGGCCCLCWKIRRRAVAKASKNKVGAYELLAPNTTAPEGVAELVNNQAVTPFPLHNSTSSQIASSAHSSLAITPYPLPVPVPPIVISPSEKTLYHASRPSASSITPTHSPLSAASSPHSGSLTQVVTPFPLTGIATTTSKPANQLYPDNRPSTSTSSSVSPYATHHAGPSTSSFVSATYRDPFVEAQPQVSLEAQGSPYNPENEHMDLPPEYSEDGPTVLPVQTLSTQTSTTSLQPVRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWB8</accession>
    <name>A0A9P6JWB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome c oxidase subunit 8, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome c oxidase polypeptide VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_888789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion inner membrane</location>
            <topology evidence="1 7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWB8"/>
    <dbReference type="OrthoDB" id="9974841at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="80" mass="8663" checksum="71B32E28BFA83BA9" modified="2023-09-13" version="1">MSLSILARSSVLRQQALAGARSFHASARSSSAHGDYHHLPFAFPGNKKIAFGVKLTTYLVVGFSIPFAASWWQIEKSKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWH0</accession>
    <name>A0A9P6JWH0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_901340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWH0"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF82">
        <property type="entry name" value="HOMEOBOX PROTEIN VND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="145"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="147"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="359"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="407"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="56307" checksum="DB29DCA929C8D07D" modified="2023-09-13" version="1">MNTANREALLNILSAARKTKALVSSYRGPQKSSPSGTHKATYTIPSLKLPYPDDLADTIRSKSLPLDVGSEISAKIQRCIVDTQRLHTSNFQATCTKLLEETPTTASHTLFTKLAAEYERSYQTNYIAWIRSMLSQYLSRFPENDNSERRKPLFNAAYTPVLEKYFQTNAYPSALERRILAKKSRMTARQIEVWFQNHRNRSKKDGILLQRPHFGRLPICLDDLEREALGINSSPLTEDESSDDEQTVIDSSFIEPVDNFTSSAPQHAFPTQYPPHCNYDPFPMGASPSIFPFPQWPRKPQSSSANKSPVDVEELATLFASKLSLRENISRTIKEKTMTPTNNLPWFCATVTLPPSAPHPALVQPTPDSCALNPRTRRFSPFPSTTKAFIPRRSHKPRLPSRLPNWSRSSPPSKSRLSARTASLESISSYDSSSSSSSLDELATPPLTPLQTPGLIFNDLFENTLSFDFPDFSPSTMSLGLDASTKLHGGFAPIFSSFQYATSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWS6</accession>
    <name>A0A9P6JWS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWS6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="462" mass="51034" checksum="D9DD5C4C2B25DFBB" modified="2023-09-13" version="1">MVKIGKRVASPPRRVKALQERVQKRTAQLESGTHITQLAEPRQNIALLQSRRTRHRYLAPSSLFGESRRRWEKNHQRLEGRKLAKAAKKMAESGLEGSDDMQAQELRDLPFHEQGSPEVPYESPGPGFSSGSLDKLSLSLESTAFGSFWDFPDLASLSGDDSTKTPLPSDFSGDSTDMSSLDGKLRLDKIDELGEKQLPDMKIAFLAGQPLQKPHQILSGVPSLLSETSARIFSRPLNPENYSSKESLNRSSRDPYLTKRTKIGVPANVFWSISSSGTSSGRSKPSRSAVLRFDELQEASSAVINSSAALPGHVLNKGIGWSAGLDSTVVGYPCYPISSVKELHPSLSTGICRNPMRSSKEPRTQFSTAAFQKDSIDRFNRRQAISRPYETPKVGASPRFALQDTPKMTHMAVIAPKIHARLALDMSTARPVIDPENRQPVMSSPIQVYRWRPPGNVRFGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWY8</accession>
    <name>A0A9P6JWY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SprT-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_32272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWY8"/>
    <dbReference type="OrthoDB" id="20772at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099:SF0">
        <property type="entry name" value="GERM CELL NUCLEAR ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="2">
        <location>
            <begin position="249"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="473" mass="52747" checksum="68BC46D619F02E2F" modified="2023-09-13" version="1">MSSNAWLNAHHATYGVPLSGLQRAGSEIIPDSEEERIRHRRKEFNVPSKVAEVIEISSESEDESEVGPNTRCTVITMSPTKPAAALPGSAQRSSGKKAFKSFRRIISSSDEESEVEILEVRTMSGIDTTIAVQNTLKGKGPLKQDNSSPTSVLSENDFFKPREKEGIIVLDEPRSSHKPLLIKKGTPSTTSRKPKFPGVGIPDSSISTAAPSGLSEEVVSTPTTRQSAQKAPRTPRTNSKKAQEKEKRDRLHAYAQQLFTDLNATVFDDQLPTSTQLIWNTRLLRTAGRAKFHRTREGAETTEIELADKILDCEERIRHTLSHEMCHLATWVINQKLDEHHGPLFKHWANLVMNKHPEIHVSVKHDYEISYPFQWKCQKCEKIYGRFSKSIKPEECVCGVCKTGRLIALFTTKKRTKATPNISRLAASKPQDSPRAVTANDMFDEVPTESGSEGDVVDMLTRSFAATSLTLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX10</accession>
    <name>A0A9P6JX10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Clavaminate synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX10"/>
    <dbReference type="OrthoDB" id="438224at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="38737" checksum="B1491AFC9CCBB234" modified="2023-09-13" version="1">MVEYTPEGAVVISYPTLVASPESVLTSIEKGFGSDPNCLGIIVVKDLPKEYVHHREKLLKLAYHFGHLDEGIRESYTDPSSKYSFGWSHGKEIMNGKPDTLKGSYYANPVHLDLKASAEEKEEFPEYYGENIWPKADERGVEDFREAFIQLSELIYEVGCEMAIACQPFASTYLIDSTVSLSDLISKSRTVKARLLHYFPPSKNEAPPSDDDPVDSWCGFHKDHSMLTGLCSALFLRHKEDGTPEVIKPPSPTSGLYIRTRGGQLTRVSIPPDCLAFQTGEALEVATNGRLLATPHCVRVGSMTSTDEVSRESFALFMGPNTEVQISPTLTYGQFSKQIFSEHYESTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BCM4</accession>
    <name>A0A9P6BCM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158169">
        <property type="protein sequence ID" value="KAF9521277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BCM4"/>
    <dbReference type="OrthoDB" id="5598737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29336" checksum="4544930AC16AFD35" modified="2023-09-13" version="1" fragment="single">MDHSPVSRVSYRPYPSTPIEKVTYTAGESSELVSPQRRPRQRGYTRAKRPSTRAHAGNSPTRAIRGLTPSSNSTTYDLLHPDNTDTTSNLSPQNTDSRFRNTSPLRPTLDEAYLVFLEAVSSGECAFYQLNQVMFVANGWNIHKSEAHGWYHLQSASIGLTDTVTVVCMCPEYRNRDHCFHQRFLLDYGKQTFPVGHLFNENPSSTILFSRVKDVLLEDAFINHFSVASHLGHNTVKNRVIVDHHGDDKGGGSWNCARDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E428</accession>
    <name>A0A9P6E428_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phytase A</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Histidine acid phosphatase phyA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Myo-inositol hexakisphosphate phosphohydrolase A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Myo-inositol-hexaphosphate 3-phosphohydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_823162</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol 1,2,6-trisphosphate + H2O = 1D-myo-inositol 1,2-bisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77131"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1D-myo-inositol 1,2-bisphosphate + H2O = 1D-myo-inositol 2-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84142"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:77136"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157960">
        <property type="protein sequence ID" value="KAF9522115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E428"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF24">
        <property type="entry name" value="3-PHYTASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="41"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="179"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="410"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9522115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="443" mass="49525" checksum="93B418DCCC3EABF3" modified="2023-09-13" version="1">MNVRAVEHVRDQVVLPIVERSWAAYTPYYAVEPYEQPPVDCKVTQVGCIQRHGARYPTSGSGPLIQSAVAKLKSVDVYTDHRLDFLKKYTYTLGVADLVTFGALEAQLAGEMAYERYSHIVSHDKLPFVRTSGGQRVVDSAQNWTLGFSIASGRVYEPPVSVILSESDGKNNTLDDKMCPNAGYPDEYTTIWTNIFGPPIADRLNAQAPGAGITPEDVPSLMSLCAFDTVATSSLSPFCQLFSPEEFAEYEYLGDVEKYYNTGYGQRLGRVQGVGYVNELIARLTNTPVHDTTQTNRTLDASPLTFPLNQTLYADFSHDNQMIAIYAAMGLFRQRKNRDLDPTRPDPERTWIASRLTPFSARMVTERLECDGHSSWKNDGGLEGSITSKKRSGEYVRIFVNDAIQPLEFCGGDRDQLCELDKFVESQVYSRHDGEGDFEKCFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E445</accession>
    <name>A0A9P6E445_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_911480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157956">
        <property type="protein sequence ID" value="KAF9522203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E445"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040328048" evidence="2">
        <location>
            <begin position="18"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="29915" checksum="A7395CFB2FA58C1B" modified="2023-09-13" version="1">MKFILLTALVVAATTFAAPTPTFTQRTTDIDLADHGNYRRGVDNTNVDLADHGNYRRGTDVDLADHGNYRRTVDNSNVDLADHGNYKRGTNVDQADHGNYRRGVDNTGVDLADHGNYRRAVDSTDIDQADHGNYRRAVGNTNVDLADHGNYRRGTEVDQADHGNYRRALDNTNVDLADHGNYRHVVDVTVINCADHGIYRRGTEVDQADHGNYRRDTEVDLADHGNYRRGTDVDLADHGNYRRAVDSTDIDHADHGNYRRAVGSINTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4E4</accession>
    <name>A0A9P6E4E4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MADS-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_777192</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4E4"/>
    <dbReference type="OrthoDB" id="1898716at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945">
        <property type="entry name" value="MADS BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945:SF534">
        <property type="entry name" value="MYOCYTE-SPECIFIC ENHANCER FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="16461" checksum="1D8014961CD3E9D0" modified="2023-09-13" version="1">MGRRKIEIQPITHERNRSVTFLKRKNGLFKKAYELGVLCSVDVAVIIFEERPGHHVKLYQYCSSDIHDMVQRHLRHDGEKDTRGPPDFSGNANTKLEDLGDDNDEDEDDDVPRKRGRDGKLKPDMHGSGVRALNDPLNLLALFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4W6</accession>
    <name>A0A9P6E4W6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_887458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4W6"/>
    <dbReference type="OrthoDB" id="2752889at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="40317" checksum="3FD461282173DBFF" modified="2023-09-13" version="1">METTRSSPSWSSSYVHRIDSGSTDESGFSSNLVTPTDEQELFLPTDGIEARLLGPLGGIEKGNKDHTISDLNVEFGDHNDDPPLVKVRPYSRGVPKQLETMDKDADLSTMASQISMAALDSSVSMSSLPSASELLAQSRRRSSALYHLPNAHISVEDIEITNSEAEDASLIRFEDFIPSMNDMEPTPDLEFSLSWPADLRSHIENVDPRACAVAITQALLFLPWCILVGATIVLSPAHLDMIAFSDSCWAKFVDKPSSPIYRYAYLAQYGMEHVTIFCGIVFLIIWFLPYAGWLILGCLAAQFSWTWNDFLEDKNIALGEDERQTVYQLAKTAWWNGDVEETEFVNGKYYSQGSLGSEQNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E534</accession>
    <name>A0A9P6E534_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E534"/>
    <dbReference type="OrthoDB" id="3139566at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="63405" checksum="61B3D9B49689DE43" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5X7</accession>
    <name>A0A9P6E5X7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_910953</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5X7"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF84">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="141"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="640"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="666" mass="71355" checksum="A170D57CA523541F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Q6</accession>
    <name>A0A9P6E6Q6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_862699</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Q6"/>
    <dbReference type="OrthoDB" id="4064873at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15486">
        <property type="entry name" value="ZIP_Sip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="231"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="813"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="945"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="865"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="981" mass="108290" checksum="9D8EA941F7FD682E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6W0</accession>
    <name>A0A9P6E6W0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_775117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6W0"/>
    <dbReference type="OrthoDB" id="3172935at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25546" checksum="2BBBE407A71CD422" modified="2023-09-13" version="1" fragment="single">VNLACKAVLAAITNLDYAADSAIESDQSKTCTQIRASSLRRQCFADIASKHELELELLRDVDIRWSSTYLMIYRAVQLEPVIKDFLHSATFEELRRRCELSPAEWSALTTAGRILKVPFKFQQALSAEKTPTLCNTIGSFYTLMSSWKALQKKLEEENPDSFGAEAEIIQAGIDKLQEYFSRTDDVPACTVAMSKPPHHFVAIHHIYLCSSQPRFEAKTLSKTRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6X2</accession>
    <name>A0A9P6E6X2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6X2"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="84"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="556" mass="64325" checksum="EC81C1F7EF6E6EC8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E758</accession>
    <name>A0A9P6E758_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein BZZ1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_647994</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E758"/>
    <dbReference type="OrthoDB" id="8783038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20824">
        <property type="entry name" value="C1_SpBZZ1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11912">
        <property type="entry name" value="SH3_Bzz1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035459">
        <property type="entry name" value="Bzz1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="F-BAR" evidence="9">
        <location>
            <begin position="8"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="8">
        <location>
            <begin position="411"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="504"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="573"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="634" mass="71138" checksum="5AD189A13CCECBBF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7G3</accession>
    <name>A0A9P6E7G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_647200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7G3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="12037" checksum="FA410F39EDEC48B3" modified="2023-09-13" version="1">MWNHQGTFCQLYRRKLLVLKDHIRRIGVARSVGLLQFFLQSGSWLSMYICVIVSLRTRLPAFCNDEEMKTSSSFEPIKSTCRRIGSITNKFHYHKAEGSINPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E820</accession>
    <name>A0A9P6E820_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E820"/>
    <dbReference type="OrthoDB" id="3190888at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="173"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="35098" checksum="7971DACE99FF8369" modified="2023-09-13" version="1">MGSSTSFQSVINSSLGAVFVGFGVSCIAFGVLVSQMASYFKNFPGDKTLFKFLVVSILLLQTADQMFIGHIVYFYAISNYANPLALVQSTTTWSFLLQLLCGAIAGAVVKSYFGFRVWRFSNRNYWITGLILFLTLGQLALALVFTVEAFKLPSVFEVHKLQTLGTISLGVGVLTDVVTAGALCIFLNRLRTGLSSSDSLVKSLVRYAVNTGALTSTLSVSVVLLYNVLPTTNLAFVACYFVLSKLYAISFLATLNTRRSVRGSGTDHQGNTDNNTNMFALGTRLPSMGPSDLDQWDKVDPPLIHQEKLYGQPLPILTKMQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8C1</accession>
    <name>A0A9P6E8C1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8C1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="8640" checksum="E5D9327739158BF7" modified="2023-09-13" version="1">MDFRDENQRKDLLNALSSPQFSSVPNIEIVIQLIGTESIDVDVPFLINFPSQVSLECPKIQVAIRRIENFDDEGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E980</accession>
    <name>A0A9P6E980_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_595347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E980"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="45824" checksum="D68D552E7B2B118C" modified="2023-09-13" version="1">MPSLPHEIIDSVLSHFSPSRQSQCNVPEIETLTSCALASRAFHDSALPHIFKRVEFVLRGNPQTFVKRCVGFKPLIEANKAIGNSVKILIIEGCEKSLLLLSEVLSLLPNVSHFELGSVVKTMCWVDFDEQTTAAVSSFWKSNPLTHIQLQQVEALPAFEIASCRYLQSLQLHHADLLPCSNSTKLLSLTLAPISKFDCAYSPQALESLAEMPGLFLELEELAFTIGGIDTVYALNRLLENAPNVRILSLRHSYGGLYHTDGQNTPDLTPAYLRILSIHYTLPDNLAFPPSILQLLKPRTNAASPIEELTVEMIFEDITPEEFILRFDPQIGWAKLDDLLSDGHYCNLSKVQISVALGLTERAISNSELYAEAHSNFDVLLPQVRKNVEVIEFDFRPYCISEPSLLFQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9R6</accession>
    <name>A0A9P6E9R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9R6"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="82"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="563" mass="63561" checksum="DEC4973ABBCFF040" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA68</accession>
    <name>A0A9P6EA68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA68"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040372829" evidence="2">
        <location>
            <begin position="18"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="96"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="149"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="154"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="256" mass="27128" checksum="A978BDE050D56995" modified="2023-09-13" version="1">MQSFVFASLILAAGASARTFTVANKCTYTVWPAMFTDLNVGQNIPSFPTGWEALPNTQVQFPVPDDWKAGRIWGRRGCDFTQKDKPDYLQCMSGGCNGGLLCDPHSGTGVPPASVAEWTLAAGGDADWYDVSLVDGFNVPMAITNNAGCAVADCAVDLSASCPDRLRGQFNATGAAQGCNSACNANLDGNQANSPNCCSGDFNTPAKCPHTGVAHYSFFKQACPNSYAYAYDESSTTALWTCPTNLKADFTLTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA74</accession>
    <name>A0A9P6EA74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_772071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA74"/>
    <dbReference type="OrthoDB" id="3184970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17873" checksum="1FB529CE38A390CC" modified="2023-09-13" version="1" fragment="single">SDNVQFYLHRKNLEVNAGAFPGAEFETKGEVVQLTEPARTLEIVFRFIYPRRYPDLDGLDFEALLEIAEAVEKYEVFPAMFPTNSELRKFIQEHPIEVLLHALKHDHRNLANEAAPYLAFSNTVFDKLPDHYLLHWVSWQSSAFFVAYVLVKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB11</accession>
    <name>A0A9P6EB11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_818046</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB11"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="43"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="48421" checksum="CCF9B854FE8894E7" modified="2023-09-13" version="1">MSCALENTSPDRKKTIAVSSRLKEGRALVEDVWSIFGAANLPTDCISLGQGYMNFAPPKWITDAAKEALDKIATNHYSPPRGLLRLREALKQHYGSQLNRDLDVKSEILVTSGADQGQYSVCTAFVEPGDEVILFEPFFDPYLRWVTFNGGKAVFVALHPPADTIEKPSSHDWTIDLEELRAAITPRTKMIIVNTPHNPVGKVFTKDELIAIAALAEQFNLLVMSDEVYDCLVFDGKEHVRIASLPGMWDRTVTVGSAGKSFAATGWRVGWLIGPKHILQPTLSASTRIVFCANSPLQEAAAAGLELARTNLFFETQRQEYTERRAVLCEAFDRLGLKYSLPEGSYFVLLDVSRVQMPENYSFPDSLIGRGRDFRVGWFMANTIGVSALPISEFYSEEHAKIGEAFIRFAFCKDLDLLRNAAERLQNLRKYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB53</accession>
    <name>A0A9P6EB53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_908981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB53"/>
    <dbReference type="OrthoDB" id="270624at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="364"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="455"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="587" mass="64647" checksum="3D7DCC3572355A69" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC93</accession>
    <name>A0A9P6EC93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_770268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC93"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="383" mass="43141" checksum="81CBBAD3F1C3141F" modified="2023-09-13" version="1">MEEISAGIVFRLLDHISDEIPVNLISKPLLQRHHFLGLTPDDSEYLIWPSGNQSHVLQLLSTEPFPSQEHTEHLSVHYTADKEHLLAHVRITPELRLVFLWDMDHKDWRYHNVDTMPFPINSYSNFNDAVAVYSPDDFLQEQSHEVHVSGDQDEGDDSYWNAYSQGDDQDSNGHLPTAKSNDNLNSEDAYWARYSTVQGTADSTIPSPLPIHRKPAQSISADSNQIPDRIIIPPDDFLANHVDLYNPLEPPSPEALSRRLEALSALASTQLSQPPSRDPSSPPLFDESPETSDSDTASPHISLSEVTPPVQPEPEMESSPPKPVADEFVVVNAEEDQEDQAQQVLQDNIKNLYKLWRLGRGKSCPEADKKLFLQNVQRALEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECG4</accession>
    <name>A0A9P6ECG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_738750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECG4"/>
    <dbReference type="OrthoDB" id="3249498at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052055">
        <property type="entry name" value="Hepadnavirus_pol/RT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050:SF7">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="38515" checksum="4C74809810D98BE7" modified="2023-09-13" version="1" fragment="single">LLCWIGTRKLGIDGLHVYMDDFYGWDFTDKLVFFHHRLRPARQVQLLILWDFISCPYEDKKQDHDELLKIIGFWVDANGGSISLSPDSIEEIISHVNTFLTTSDRKPRLRIWQQLSGHLNWLLNVIPWARPALCEMYRKMSGKSHSHSPIYINAAVVEDLTWISQVIPDAIGVRFVDSLHWHDHEADMIIWTDASLKLALGFAFSNRGFVYQLKPPVVKPGNPPPDIFFLELIAILSAIHYAANLIHPPKRILIHTDSLDSVAVLSSLAAKTELHNAPLRAISQIILLTGIDLRVQHIEGKLNIRADLLSRMLLSEYERLFPSDRVDMFEPPRELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECJ1</accession>
    <name>A0A9P6ECJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_493316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECJ1"/>
    <dbReference type="OrthoDB" id="3205788at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="263"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="31492" checksum="AAB333E07776994E" modified="2023-09-13" version="1">MPREVEGVPEVPPSPLSFSVNLYPSLDVDNLTLDLRTEKNPIPSQFSIDLYSLSETLTSSQVFDLEDHEEPLQTQQMSVPKQIFIDLYSLADINRASESVTEVAPIPKTACISLYPIINVPAPLRQSEDVADIPPSPTNISIDLHPFPWIASSGPGVPTVTQASENLQTASSERVLISGSSFIVQAGEEFRLPEAELVGIQDSTEEEQIQDRKYEGEKITRSSEAVDLPIASVSSIPVRDPDAMAANVLETEQRGELVRDGACFICKEVGHIARDCPKKQRSRKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDI1</accession>
    <name>A0A9P6EDI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_856169</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDI1"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045016">
        <property type="term" value="P:mitochondrial magnesium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.330:FF:000002">
        <property type="entry name" value="Inner membrane magnesium transporter mrs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="313"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9527438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="454" mass="50980" checksum="04E7B512C12F9A9E" modified="2023-09-13" version="1">MHRAFGLACASHVNLQNAHLYATLVSRSSRRQFIGTLNAWHYQNRPSLLRRNWVHEPHISPRSAMFGAVRSSWSWKSHFRGRETQEPSDNEEDAARAAILDKVMKGRQPADLMLRCTVLDSEGHVKTISGQFKKSDLSTEHHLNARDLRKIDSRIPNLVPTILVRKEAILVNILHIRALVKADTVILFDTYGSADSRLHSVFLYHLEHNLKASGSGTPYEFRALESILLSVLSALEAEMVFIRNLVGGLLAEMEDNIDHDRFKRLLHYSRRLAGFKNRAGLVEEALDEVLGQDEDMDAMYLSDKKDGTQRGDHDELEVLLESFSKQVEEIVNEAETIESNVQSTQEIVELILDSNRNALLALDLKVSIITLGIGTGTLVAGVFGMNLLSHFEQHPYAFFVMSGLSTCLAFGVGWAGLRTLAKIRKVGLSSNNTKKRSNSWLPLPLRNRNPGGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEN1</accession>
    <name>A0A9P6EEN1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEN1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="9035" checksum="C9C56498B476AF1D" modified="2023-09-13" version="1">MEEVQVMEEVQVMEEVQLQVPALVLVLAILVIRIVHYLLTTPNTPKMSNTNTTTTTEMLKATKRTAKRKRMRRRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEX1</accession>
    <name>A0A9P6EEX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Queuine tRNA-ribosyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_814190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEX1"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="57"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="312"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="456"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="562" mass="62467" checksum="91ACECBC060958D8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEX2</accession>
    <name>A0A9P6EEX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heparinase II/III family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEX2"/>
    <dbReference type="OrthoDB" id="3476529at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38045">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38045:SF1">
        <property type="entry name" value="HEPARINASE II_III-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="774" mass="84877" checksum="C33730E320BF495D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF68</accession>
    <name>A0A9P6EF68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF68"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="446" mass="49984" checksum="30EC7597D919BFED" modified="2023-09-13" version="1">MDEEYDVIVLGTGLTECILSGLLSVEGKKVLHMDRNDYYGGDSASLNLTQLFRKFRDNKEAPAELGRDRDYAVDLVPKFIIANGELTKILVHTDVTRYLEFKQIAGSFVFRDGKISKVPSTEMEAVKSPLMGLFEKRRAKKFFEFLQGWKDEDPTTHQGLDLDKDSMKAVYEKFGLEPGTQDFIGHAMALYLDDDYITKPARPTYDRIILYTTSMARYGKSPYIYPLYGLGELPQSFARLSAIYGGTYMLDKPIQKIVTDASGKFVGVTSNGETVKAKQVIGDPSYFLKSDDGKIRVIEEGKVVRAICILKHPIPETDNSDSCQIIIPQNQVGRQHDIYIAMVSATHNVCAKDVYIAIVSTVVETSVPEKEILPGLNLLGPIHEKFVSITDLYTPTSSGEADNIFITRSYDATSHFETVVDDVQDVWKRVVGTPLVLKKREVEVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFD1</accession>
    <name>A0A9P6EFD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_836288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFD1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="141" mass="16179" checksum="6A28DDF39A526FA8" modified="2023-09-13" version="1">MFLLLIYCFLIACVLLHIFIPSLCYLLKIRSVTIKDDVTMFTSPNPRAPLELYLEDQLPFIFQAFAVVKLDKLRDHRVAEERAPRKPALTTPQHIVINEVEQYHQVSKSHRSIGLGEKNHTRIAILSLWCYLNDEASSTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFW4</accession>
    <name>A0A9P6EFW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_883528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFW4"/>
    <dbReference type="OrthoDB" id="3357408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="18769" checksum="8EF8B0978E255351" modified="2023-09-13" version="1">MASAASSIEEAQLDGIFLECVAIVDLTLGFYHLIQAFVLFKGEGVGYVRCANNNRRYDAGEVQTCKGIHELHSSEAFVKIYRCWIVWNRSWRMVIPSIILWLGTLGTITWIIWIESSLHAKVLLNAKQLRPAGASFWVLSIVLNIITAGLLIYKIWRVEKQADCRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFZ9</accession>
    <name>A0A9P6EFZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFZ9"/>
    <dbReference type="OrthoDB" id="3068366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="388" mass="42099" checksum="314F9191360746BB" modified="2023-09-13" version="1">MRCHSSLSLLLTDPFSQRSRPTCKLSLANVSASTSLEPNAMEVDLPSLAVSVPSSNVWEETQGVPFPSASSSPPRKHALFQPTSTVLGDRSNRSTFEDHHTPPSPTEATPPRKRSRTAALLPMPKLSRTHRFSSLPPRGVSSRTPKSASSLLSSSASPSARSLPQVMPNPCEQFTYTFPTMSTTTMTAATRSTNSQLPSITDLIQSTSTITAQRPVPPPPTQTPAPPALRRRKPNSSEMKILGSLYRTLVLGLANKHTQLASRQDPSGTPYEDRPTTMAQLAIQDAVLADRLRWYLTANGGDVSLSRDADQDAMETENEDPNQSTDAVSASPLLPPGISTMGCITSYQQMVSSLLIRRRSEARSVKAAKKSGDRRRTRSKLFESIAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG09</accession>
    <name>A0A9P6EG09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_854533</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG09"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="77"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="229"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="577" mass="64190" checksum="74CC932F4CF82A89" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGJ0</accession>
    <name>A0A9P6EGJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_906389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGJ0"/>
    <dbReference type="OrthoDB" id="3346251at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="35565" checksum="CD5C17321ECABC7F" modified="2023-09-13" version="1">MPNWNSPLELNRDAIIFAKLSSVWTGLYCWEIVTSMQLERDVILGRRKFHWPLAPYLICRYSPIIALLCLACSQSSTRCVYYTPSSTNNGSGPDDGHDPRPINCAVTYVIAFCFELSVTSASVIFALRTIAMWTNRVVTGCLCGLVAVDTLLVLLTTIQNRSKWDSVRGCMFLHPDLTYLTAMVFRIFTMAFDALILSLIFYKLGAGISWKGRTSVVRFLFRQGLMYFIFAFLCNGIAAGFLIWKPNFQLGIIAVPPASFFTAIAACRSVRYLDVFIARDNKEIFHPNATATGPVELDTIPSMEEQDRSRVVIRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGS2</accession>
    <name>A0A9P6EGS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_835656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGS2"/>
    <dbReference type="OrthoDB" id="3064941at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040226631" evidence="2">
        <location>
            <begin position="21"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="290" mass="33292" checksum="627BF138C3CD6853" modified="2023-09-13" version="1">MVKFTAPIVYAALLAGSVIAMPLSTRAIGDQDIMVAREDFNAVDIYGRDLSMDDLEEREPFGIGMAFKAIKGIFKIGKHARHAQNNNNNNKHKRSLDFEEDEVLERDLSVDDLEEREPFGIGMAFKAIKGIFKIGKHARHAQNNNNNNKHKRSLDFEEDEVLERDLSVDDLEEREPFGIGMAFKAIKGIFKIGKHARHAQNNNNNNKHKRSLDFEEDEVLERDLSVDDLEEREPFGIGMAFKAIKGVFKIGKHARHAQNNNNNNNNKKHKRSLDFEEDEVLEREYYDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHC3</accession>
    <name>A0A9P6EHC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHC3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6803" checksum="1FAF068100E17228" modified="2023-09-13" version="1">MPRAQHTSTLRIWDDIGIPVVLIIPTSIRPQSVSFHNFLVECFRDAFVALHANCEHFGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHN7</accession>
    <name>A0A9P6EHN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3 10">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_852929</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3 10"/>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHN7"/>
    <dbReference type="OrthoDB" id="7939818at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000002">
        <property type="entry name" value="Glutamate--cysteine ligase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000001">
        <property type="entry name" value="Glutamate-cysteine ligase Gcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="512"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="664"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="688" mass="78272" checksum="6AFFC6EEA2368A45" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHR1</accession>
    <name>A0A9P6EHR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_834740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHR1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040531849" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="22"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="655" mass="71051" checksum="23396C09652A4F69" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHV8</accession>
    <name>A0A9P6EHV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHV8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="353" mass="39973" checksum="AE9F8CC4F63AAB06" modified="2023-09-13" version="1" fragment="single">MSHYSRRNLMYPHGLKHSQPWSDDRRAGDTRMMDVERLRLDRHAAPLHNRSHSRTHIPSDRRSSFLNTIVPDVRINRSTYATPFDGSTWSNDYPVHTPEWRSQRDLADESNLHSFPPQIYNFSSDNRMPPSSSMLGYNYDILRHNQPPSFDSQTYHHATFDLGHEQSPPPPYTPDPATTTGRGGCSSRQSVQTARSRHPPSSSPSQMQMVRYDPNSVDHDDRQNIGSSGFAASEPPSSAGTDTRRSSNWSNSANHGSIGHFSPQPYHSEYTHFSNPSAAYPHYNMTSYQNYRENHGDIFEDVDDDDCMSDGVASDEGVYYSSDGGQFDSFGEDEFEVFSDDGHTSPIDDFYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIJ5</accession>
    <name>A0A9P6EIJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_852400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIJ5"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="192"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="683"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="738"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="758"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="836" mass="94124" checksum="012CB2B6A4AF9897" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIM3</accession>
    <name>A0A9P6EIM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_258564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIM3"/>
    <dbReference type="OrthoDB" id="3062404at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="142" mass="15820" checksum="DE5B658EC9A24089" modified="2023-09-13" version="1">MCVLLCKRHSATETNRTRETVRKIVLLIAETNLTSTIVALSTLVLFLVLKGVYFTFPSIILGKVYSNSLFLILNNRIYLTDDVPGGIKIKNGPEKLQKDPYVNGNFGMTILRTKESSGEGANVEWMAGVRVDVHTARHLDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIN9</accession>
    <name>A0A9P6EIN9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_926443</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIN9"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="439"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="490" mass="53546" checksum="BE53DEFD87530752" modified="2023-09-13" version="1">METISMFLDIDCAMDQGLPEFIEDKNTQSVNYVYASSGHAAKAYDFQLNPHSSSLSYDERWFEAVNWDLNDLASPPPNPGRASPRVENVSPPTSSCWSSSPRASCDASPDNSPTTINPLATLKSGFPLSTTVKLSDIRTDQGPEFGPISSSGVGQLDIPVSDASQQKRTNGRELPTTVNGWKNGSAAGRPVVRPTSFPNDRSRYGLTPPTAEYASSSWNAQQFPRSPSGTSTVTAAIEEALLESAAEDEDSNASDSDDYRPSRSPSVSRHSTRTSLSPPCFTSSKNPRFSRKTTSKKSSRKAKGSAALALAVVMQLGDAKRVAKTEADPDPGDEHYDPVKMYQDINGYEIIRKRKNQPIPLPIPIPNLNKKSRGRKVPFVANPEDLAAASSGLAGVTHSMVKIEDPDDDYILKTSRSKRRKITPAVPPVPPEDGLERSYVCVIPGCGKCFVRGEHLKRHVRSIHTHDKRCDKSFSRRDNLGQHVRLHLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ58</accession>
    <name>A0A9P6EJ58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ58"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="54" mass="6296" checksum="51A17B1CF914A430" modified="2023-09-13" version="1">MPRRFWTQKFFLGDFNTLLPVLDVQTDLPYPVSTAKGSAIRSCLRTSELRNFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK34</accession>
    <name>A0A9P6EK34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK34"/>
    <dbReference type="OrthoDB" id="3225366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="30382" checksum="B497F0D864540EF8" modified="2023-09-13" version="1">MSTVPHMSERRNTGQSQLSSINTSLRAESKNPSQQSFGNTLPFQSGTPGNFTQHEETGGYFSPGTMRDYDTINQRPPPHQPTKSLLSYALPNAVASVKDGWQGTSSSGAVVSGLLAGVASQLLGTFTDADISPSGAKGIIVATCYAAIFLNINATIGSFVLIDRLGELGFEAARLDMLGRLDQLELVGHNHSQVNQLLKEFGAGRMWKYMLIHWLVTFYLGILSLIISVLTYVLLTEGTAIQAVMCVLVGVTLVPTTVFILFGGRSRNARKKVDVSQSKVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKY4</accession>
    <name>A0A9P6EKY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_762607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKY4"/>
    <dbReference type="OrthoDB" id="3256015at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23353" checksum="2CD36A5A93B5A6C7" modified="2023-09-13" version="1" fragment="single">QTIARIIPTTSIPSFVAPGTRKKKQDIKKTDLPPQLQAAFSSSFVPRLRLLLGRAKPWDSPTANDLKSAWSSVFPGEVPLDLQSDTGKIVKKLIEERVGNWRHKFASTALKYLEKSLLPNLPDDSKTKRAEYCVWAVSKPDDKHPFFYSSIEFGESDQISRRGIFQSSIIVETLAQHLNLILPLTLDPKNQNDWPHGALVMSILAVCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELZ1</accession>
    <name>A0A9P6ELZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_759670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELZ1"/>
    <dbReference type="OrthoDB" id="2538408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="41708" checksum="72A3233CF209B4E4" modified="2023-09-13" version="1" fragment="single">AIYAVYTSPSHPPIPNHLPTLIVTPHGQPSNILYSYLHTNYNSENYLLTPSPQGDLCVAKLFPPRPREPGKASASDPGHGSSPSSRVVRCEASRNLKWSIANTGVISPIYKLSLPSPDSPDLPLFQISKPNPNAAFWSMFYFAYAGHNIPPKRIEFGKIQKNPPGPNGGGTRISITGKTPEEKAVWQTLGEGNEDCVEWVVLCAALNLLDDEIMKAADKNPPPPTPGGAPNGRPTPVSLRDPGPGGPNGGPPPGSRPGPPGPNGGSMPPPGQRLPPPNGGPMPPGPMGGPPPGGFPPGRFPPGQGPPPNGFPPSQGPPPGFRGPPGPGGPPPPGGYGPPPPGGFPPGRPPQGRPGPPGPGGMPMQMGPGGPMPPPGQGGPPPPGTFGGRPPPGQMPPPSQQQMRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELZ4</accession>
    <name>A0A9P6ELZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rad17 cell cycle checkpoint protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_868110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELZ4"/>
    <dbReference type="OrthoDB" id="10265971at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057927">
        <property type="entry name" value="RAD24-like_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25812">
        <property type="entry name" value="RAD24_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Checkpoint protein RAD24-like helical bundle" evidence="9">
        <location>
            <begin position="335"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="570"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="619" mass="69529" checksum="F1920FACC71B3705" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM41</accession>
    <name>A0A9P6EM41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_848408</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM41"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14280">
        <property type="entry name" value="UBA1_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000254">
        <property type="entry name" value="UV excision repair protein Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="153"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="342"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="203"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="103"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="387" mass="40784" checksum="E2631DA046136FA3" modified="2023-09-13" version="1">MKITVKTTQQKVFQVEVEPAQTVADLKVKIQESQGHLAGGQKIIFSGQILTDDKTVESCGIKEKDFLVLMVAKPKPVPSTSIAVAPAPISAETSELPAAPVPAVAQTDPSAAATAAPTMAESSVPAVSSESQPTSTPAPAPGFGDPSSFLAGDHLQSAINGMVEMGFPRDQVLKAMRASFNNADRAVEYLMTGIPAHLEDPQAAAQVGTPSAPQLPTNPTSATSQTPAQSGNQPQNLFQLAQQQQQGGTGGSVPTTGAATPVAPPLNLDALRDNPQIQQLRQQLDQNPELIQPLIQQLATQNPMLAQAFAQDPAALLRILGLDVDGDEEGVPPPGSHVINVTEEERAAIQRLENLGFPRQVVLEAYFACDKNEELAANYLFENNFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM74</accession>
    <name>A0A9P6EM74_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_891583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM74"/>
    <dbReference type="OrthoDB" id="621413at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF108">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="634"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="886" mass="98871" checksum="87A4DF246B4CFC18" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM89</accession>
    <name>A0A9P6EM89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM89"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="548" mass="61221" checksum="4C4F81C9B8933CDE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMA2</accession>
    <name>A0A9P6EMA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pleiotropic drug resistance ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_868268</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="560"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="731"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1159"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1188"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1230"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1268"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1297"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1419"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="112"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="823"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="772"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="776"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="800"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1461" mass="163508" checksum="DA523C1611655F8E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMK2</accession>
    <name>A0A9P6EMK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMK2"/>
    <dbReference type="OrthoDB" id="3346544at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="283" mass="32005" checksum="4194E27965718B5A" modified="2023-09-13" version="1">MYIVATLHVVLGIYRVIQAYIVVENPKGPISYLYDVTLWSFRANNVLLCVMTWLGDALVIYRCYYVWSGNFWVILLPTVLLFATVGVDAFILYWWDHQLAFSATFNILPWLNSIYPLAFAQNVFTTGLIGYKIWKQHRKSVSVGIVDRGSRLGLLHILRIIIESAAVYTIQLCLLIILYALQNNFQVILQDAIVPSIGIVFVLIAVRVHNAKNRPIVMHPSLSMRTIPAWLGKDELTDVEMQDSGLSTASSGPRLDLDDNHFSSASSRPSSNRLSMLPDMEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMT4</accession>
    <name>A0A9P6EMT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_808858</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMT4"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000005">
        <property type="entry name" value="Mitochondrial phosphate carrier protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="21"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="118"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="222"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="312" mass="33852" checksum="DE443CA38D0D6EEE" modified="2023-09-13" version="1">MSSITKPWDARYLGPVPHDASYYAKCMLGGVLACGITHAGITPLDVAKCNMQVNPAKYKGLVPSIKTLVAEEGSRGIWKGFGPTFVGYSLQGMFKYGLYEVFKDTYMNLAGQENSEKYKPLIWLAGSASAEVFADIALCPLEMAKVKIQTSPTGTFPTAFGAAMKEMSRTKIETRFPFGSLVPLWSRQIPYTMAKFFFFEKIVQLFYTHVFPEPKDTYSKTTQLGVTFASGYLAGVVCAIVSHPADSLVSQLSKASNKGKSVGTIASEVGVMSLATKGLGTRVIMIGTLTGFQWWIYDSFKAAMGMGTTGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN12</accession>
    <name>A0A9P6EN12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_903278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN12"/>
    <dbReference type="OrthoDB" id="3070764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="473" mass="52265" checksum="98C75C3F7CA5BDF7" modified="2023-09-13" version="1">MFQGLKLSKGNASANSHNGNSNAFQTQSNNKSRSSIFSWKTIINHNVTVASHHERLPTYPPEHSTIPLPPIVTSLPDSAPSSRMGAFNDYKPSPAKETPPARPGIGSRDKQNSGYVNTRDLPITPESIYSREALTTGSILKDDGFPRLKRKRMKIYLPPSTQAEIIAYMTSSIITNPKLIPLWSPPPTLQRGTVQRGKRVAVGDVGYFDSDGGFRVMFNVFWDQNSNKECGFLTPPYFNQFVSPQSLLFRSRSQSMAINGSKTGHSTPSDGAPSNRRVDSDDSAIIVRRKFKDPNGYFHSKMAVDVKYAKDEVIYSLSPHKSKLAMFLCFPQGAVTYELDESVNTALGYYLAANAEQWCQHFDRFGIFSRMVFVRGVVLAKSFASAVFRGTPQSSSSAQLRKTIKDDTLRWSEASNGFEKTIVSGQQDDFEQQGRSSSLADDQCAALEGLEVTATASAATGVSRQSFQTLRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENA8</accession>
    <name>A0A9P6ENA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENA8"/>
    <dbReference type="OrthoDB" id="3065653at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="389" mass="43422" checksum="4EB387BDBC096C14" modified="2023-09-13" version="1">MNMSATESMPPSPIAKVVEQPFVAPPRFMKVRTIVFGSVFALSFIWIILLCVVIFSEWSVMDIVERYLIVIILLVQFITVILVPLLLAGEFRPWLDAARSLCLFASHFGVAVWFIAKATSFKCSSQGANQMALCNFIIIFLLTANWIIPTLILGYSSGLAYLIRRMSKMPPPSPSSKLDIEKQTLEKSVADISFPPSIYRISRMPQTPTTPLSMATSDRQRRQSTPYSIHSNAQRMSRAPLSTPIHDRMHRQSAVQHRSMYRASAVSYPTTPTTPQTPDIYGGIQSGPPRASTLPPLNVASNPRQVPRGMYYTTPMPLSTPSQIYTPYYGPPPNMPSQQSRQSYQPSRQTAVTITPQTPKSSVQQQQRQQKTSSQQSSVYSQASYGYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENQ5</accession>
    <name>A0A9P6ENQ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_867564</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="2"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENQ5"/>
    <dbReference type="OrthoDB" id="200924at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="12">
        <location>
            <begin position="41"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme C-terminal" evidence="13">
        <location>
            <begin position="226"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="358"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9532225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="423" mass="49028" checksum="E16601309C98E1EA" modified="2023-09-13" version="1">MPIPELPGHLVQRYSQDEDWLKHHVAKMCGLDNPEKFPGSQPVSFGSADLDKLEKQDYWVCEKSDGVRVLFLIIDRHNTYRRQEGFYFPHYESPAMPLRNTLIDGELVIDVDKSTVQQQMRFLAFDCLVIDDTNVMSRPLDKRYGRLDLWFFKPYKQMLRDHPHMAESESFGIRVKEITFSYHIEKIFNDMPTLQHDSDGLIYTCVSTPYVAGTDPNILKWKPPSENSIDFKLVLRFPPSRINPREPDWHAKPIFLLHVWCGDSHGKARYEQYDDMHVTDEEWEDLKRSGEQIDDRIVEVHWDASISRWKMMRFRDDKPHGNHKSVVENIIQTIADGVERETLLDRCGPIRQAWKARLGQPSSIPPPSSTSSFPPQSRPAPSYHPPQLTKPHFSTQVSHRYGPIAQSPWSKVAGPSVVAGMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP32</accession>
    <name>A0A9P6EP32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_847142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP32"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="111" mass="12065" checksum="8AF3C1DA8AD47914" modified="2023-09-13" version="1">MSSRRPQLQIFELALTPVFLQRLWGESRGITVPLVGFTEDVVFVAFSPAKTMVSERSCVARNSCWTRRNLCRIAPPVSGCVDVTAVCSACQFPSVSGKSVPAILQGMFPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPB1</accession>
    <name>A0A9P6EPB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor CEF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pre-mRNA-splicing factor cef1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_847855</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPB1"/>
    <dbReference type="OrthoDB" id="1410009at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="13">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="13">
        <location>
            <begin position="59"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="112"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="242"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="424"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="773"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00069095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9532437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="832" mass="92709" checksum="AC0FC1CB01EAFE8C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPF3</accession>
    <name>A0A9P6EPF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_669464</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPF3"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00179">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000008">
        <property type="entry name" value="Syntaxin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="214"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="37772" checksum="A4773AF69A60EDD1" modified="2023-09-13" version="1">MSRDRLAAMRAQQGNSRKPNPYAQQDDTNYEMSDVRDSRTHLTPATPHTAAPGDMNSFYAEISSLQDTIRTFNDNVNRVSDLHSRSLNNMDDAAAQRNATQLDELVEETSALSATLKRRIKALEAQGGAGRDGQIRKQQTALVKSKFVEAIQNYQGVEQQYRTKYKQRMERQFKIVKPDATPEEVRAVVNDEQGGQIFSQALMNSRYTESRQAYREVQERHEDIKRIEKTLTELAQLFNDMSVLVEQQDENINVIEQAASGVEKDMEVGVGYQDKAVASARAARKKRWICFFIILVVLAIIAIVIGIVVSRNISNNNNNNNSTTTVTATPTPTKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPG2</accession>
    <name>A0A9P6EPG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_580012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPG2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="28972" checksum="153D948C403CAB07" modified="2023-09-13" version="1">MNQRPRVQLIYPKSKQDYLQRNGKRNVLFGTTLLGSDDEQRLLGHFAPRLQDDEGEPNDIWLLPNSNDATMTATLILYTRSQSVSTTHRSPFEPSLVLSYILPTIIRLSVLGTLKACSSIPSQKALALLLNLTPMLAQHPLEAPLENLADSYSETRQLNNTQTSTPADLIVTSSSPNCANSFRTLIPLCSLPTNTLLLPSCGIEDNRQCFWLTRCIGTGSTGNSGNVISQIPIVYIWLKLLNICIALMPGADNDLRLNFMCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ26</accession>
    <name>A0A9P6EQ26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PARP catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_416293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ26"/>
    <dbReference type="OrthoDB" id="9514740at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31681">
        <property type="entry name" value="C2H2-LIKE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31681:SF3">
        <property type="entry name" value="OS04G0690100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="33865" checksum="7B73DEFA53F7F737" modified="2023-09-13" version="1">MSSSSNQNCEFCHNKPKFPSSDYCSRTCRNNALCKECRRFPKFAGFDYCSRTCGVAAKGSTSPSVSKRASSFFNFGPKPAKASNPATQTRSVPPVYNSAVVKSVVPPPAPTVVRQSSQLLQLSSSDRRFQSVADQFKTSWRHPTPCPKVKYVYKIIFNNSMLAKYNAYKASVESRGNFAAAGRQEGNENRRWHGTHRECNLGDRGQTKLCSSKTCSLCSILRNSYDLNFWGKKTGFGSNNSKFKAMLLNLVVVGNGCKLTTDDTTLTAPPSGYDSVLAEVGSALNYDELVVYTNDAIRPSYLVMYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ53</accession>
    <name>A0A9P6EQ53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_873761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ53"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959:SF119">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="891"/>
            <end position="1187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1189" mass="133046" checksum="63E61A67A96BB703" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQL0</accession>
    <name>A0A9P6EQL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_846178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQL0"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF2">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="587" mass="65249" checksum="6F77C3225B14A3F2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQT0</accession>
    <name>A0A9P6EQT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_536897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQT0"/>
    <dbReference type="OrthoDB" id="3358078at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="953"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1266" mass="136843" checksum="ACB2C62ABA58E047" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERG9</accession>
    <name>A0A9P6ERG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-rRNA-processing protein RIX1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_842871</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RIX1/PELP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERG9"/>
    <dbReference type="OrthoDB" id="20900at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012583">
        <property type="entry name" value="RIX1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105:SF1">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08167">
        <property type="entry name" value="RIX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein RIX1 N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="633"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="722" mass="78831" checksum="747A89B87F1406BE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERJ3</accession>
    <name>A0A9P6ERJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERJ3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="20056" checksum="7CBFADA26FE7A9D8" modified="2023-09-13" version="1">MVGNEWTLNSFLRSTLQRLSLTVPRDLPNMRPDEPSEVFLPKLSTLSIVIPAIDEFDPKSLVPGIVSELEHMLNARASDFAPPDQRLKTLRVSTSHAKLLPEIQSVVAPFGGLGLQFEVTSNDITPDWCQKPVNTGLHKWQDGIDERLEKRKPARKLVPTYPEPPRSPEYTSYLESLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERL4</accession>
    <name>A0A9P6ERL4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_844667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERL4"/>
    <dbReference type="OrthoDB" id="2982757at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="227" mass="25597" checksum="FB2B40811D709434" modified="2023-09-13" version="1" fragment="single">LKICFIPSPNPQHLTIPFCPFSNPVDAAPRISTITSMSVFNTFPSMMVEIFLPSLEVAQHLERLDYSPIAHMASLLSIDDMVPGMGTDFMLTSKPRWQMKAEPISAALQRTSIRSPLLRSLQLEFIKLYKPDEEFPNILTGTWFPNLEELLLEVVSAKDQHFIEAARSSTSLRRLALSKCKNVTVRGLRPFVVERQHGFPLTIELRPTVSSKAFKALSALCDLTVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETP4</accession>
    <name>A0A9P6ETP4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_844279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETP4"/>
    <dbReference type="OrthoDB" id="829at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14819">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.200:FF:000002">
        <property type="entry name" value="Putative translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="222" mass="25302" checksum="A484DF5D3F408E0A" modified="2023-09-13" version="1">MNAESLEKLNALLDKDVDIREKIKDQVTELDKKTRTMVGLLNKIHSTPADNLPALLDSIRPVLVSCRDNIANLAVVIPENQVWRWKEMWTNSLRTAVFVAVLIEYMLTRQLLSLPDTAIYLGFKDEWNDRVNLAVEDYLHGLISVVNELSRLSVNAVTLGNFEEPIKISSFVKDIFAGFSMLNLKNDTLRRRYDSLKYDIKKIEEVVYDVSLRKLALAPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETY9</accession>
    <name>A0A9P6ETY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin fusion degradation protein UFD1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_841466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETY9"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="34"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="133"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="466" mass="49574" checksum="81540FB40F4B3C9A" modified="2023-09-13" version="1">MNFFGNGPQGMLNQLAAGMQAGGYGPRRANPQAYDEYLKAYSMAMLPRERENVSYGGKIILPPSALANLTNLDLESPWMFKLRNPANPAASTHAGVLEFIAEEGVVHLPYWMMKTLRLNEGDPIRITGTDLPKGKFVKFQAQTVHFLEISDPKAVLEQALRNFSALTQGDIIEISYNTIVFGLLVMETKPGGEGLNILDTDLEVDFAAPLGYVEPERPKAAPPVSMAEKLKIDLNSHSPGSSRPGSSLSGGFAGASTGVTTMSKDGDSWESFKGKGETLGGRKTKGKGITHRKIEQVAEGSKIIRTDNRKIVSNDTLDTGAKVPAALNLPFGQLFFGFNIAPYTPPSPPPGSPKIDDPPTSFSGSGNTLSGRSNPSASTQASKKGKEKEKAETTSSSSTSHSWGSGGHTLGKRAAASNGSVGAGGARVPQVPLRGSVKKKARSPSPEEEQDWGVDDDEDVIMIDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUG0</accession>
    <name>A0A9P6EUG0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_803686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUG0"/>
    <dbReference type="OrthoDB" id="2669721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF1">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="51875" checksum="7AA6A7B0968370BE" modified="2023-09-13" version="1">MHAATINLGELFIPLWRGQFQCAGSDRVTNWDWAVLKDAEVWKEHGRIIGDCRPYIPGSFDRYPHNIAEKVSSGYKAKEWQGYFYGLAPALLHNILPFKYWQNFCHLVYAMRIVHQRRVSASQLQEAYFHVQTFHLEFEELYVQRNPDCLHFVRPCLHALLHTPQETVRMGTITTYSTWTIERMVGDLGGEIRLHSDPYANLSERGLLRCQTNALRASFPELEKKDKGPPAYSEDLGSGYHLLRARDEYAQALAGEEGAIIKRFIEDEEEKCGNAIPDNWAGPRVRRWARLQLPSGQIARSAWKEDRYAQTAIRRARFLSLPVSGSDKPQIEFAEVKFYFNARINDVRRPLALISLLSRPDADLFEKSFWTVWSVTLQNNALRVIDAKCVTSVVAVIPHDHHCREDRSDKRFFIWEYTGLEMDLLSDATQIRDEDRDALDQDDEEVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV11</accession>
    <name>A0A9P6EV11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_842428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV11"/>
    <dbReference type="OrthoDB" id="289162at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19494">
        <property type="entry name" value="Elp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008728">
        <property type="entry name" value="Elongator_complex_protein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12896:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12896">
        <property type="entry name" value="PAX6 NEIGHBOR PROTEIN PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05625">
        <property type="entry name" value="PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="441" mass="47623" checksum="D7CF5730408302FB" modified="2023-09-13" version="1">MSSFKRKATGKQVLNVYPGTRISPASNLSLITSTGISSLDDILGGGLPLSCSLVFAAPDIHSSYGDLIQKYFIAQGLASGHRVCLVTPNPREFLKDLMWSPKGSQSSTAVGDASAVDSDGEEEKDGDDQDSESKKVKIAWRYEKMKQFKTTVGTSAGANSDREVYCQNFDLSCTIPEEVISDALRTDRLHLLEVSVSGTSGCKTGSALTPTAIVGEIIKFVSSGASAPVRICIPSLGCSAWGDLSAKVIFRFLHSLKAILRDYNYSCASTTLPPSLSAKLWGGPGWLEKVGWASDCLLTLSAFTANPGMSSIFPSHHGLLQTHTLPAPFTFSPPSDRFSTLRGLTSSGENNLAFKCTRRRLIFETLHLDVEGGTGERRTTASKLMDDGVPVGTQKDTETKPKIASVEVQMEGVFEEKKSPVVKKKKRAVAFQSDRPELYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIR2</accession>
    <name>A0A9P6JIR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_864603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIR2"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="799"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="800"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="810"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="829"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="841"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="852"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="940" mass="104393" checksum="BA3EFF5583A15E53" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIR4</accession>
    <name>A0A9P6JIR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157942">
        <property type="protein sequence ID" value="KAF9522527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIR4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22768" checksum="F1511B85C51D2ECD" modified="2023-09-13" version="1">MFGTLSLALLSNFNNLDSSTSTVAMLRNKNLDGRHKKLAGGAMIAESRINMKDRRLDKAEMWSISGIDVSGLSMAQKLRNNSSGGRQRYRDAEDLKPCRGRHVEAQSSEGSYLTLSFRPSPRDHTHTKTSKSSGHVMFSSTVAIAHDSSYFLSAIFHLKLSFTISPPLHYHKNLMVLRSLAPSAARYPKKDEKRTRRLQIASTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJJ9</accession>
    <name>A0A9P6JJJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_695123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJJ9"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="152" mass="17097" checksum="6C20726FD69974E9" modified="2023-09-13" version="1">MHLNDVLDFRSQSWRIVDLLIPPLPSEASENEAGQANSSDLFQPWLSALRECCRTTLRKLTFVGATSSYDASGALFLGDDKVLDTHAVVSSLASSGLPLPRSPSGNLPDLYSDGQLLKAGDEREERGWWSLRYQQVFREFQRRDSIMFDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJP0</accession>
    <name>A0A9P6JJP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter NIPA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_862748</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJP0"/>
    <dbReference type="OrthoDB" id="6428174at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="522"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="571"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="644"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="683"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="717" mass="76882" checksum="6B3D736791AA50DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJZ0</accession>
    <name>A0A9P6JJZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJZ0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="8543" checksum="4BD69F23E0F84344" modified="2023-09-13" version="1">MVCKYVLNDMPPSRDHAIRIPYAAARISTLAVFLFAVPVIPSLDQFLVNVSHIRISVYTALRRCGLSTFSPYAAFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKL9</accession>
    <name>A0A9P6JKL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKL9"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="29125" checksum="859703DA401A2F92" modified="2023-09-13" version="1">MSKYVDWETERVFQIRAERCVLLSGITLMIWDFVENVLDDILLFTAHPVRLPSVVYLLARMSTLAFLISMLAPSNVHTTSILLYFRVHALYRSNRWVQVFFLISCLGVIASCFIWAMVSGLCSGIFDIAIAIAILIHLRLGWLRGVGQRFWLPFRSRPEAPITDKILQDSLGYVLLAVVIKIPQILLVSALAGGYWELYSVYLDAAIMCIISAKIFRDMKLGYWTATSRPIPGLDTPPTSGLRFDHHTQNSTLLSNVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKP9</accession>
    <name>A0A9P6JKP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_897930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKP9"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="102"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="515"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="545"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="587"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="627"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="707"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="348"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="451"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="803" mass="88161" checksum="DCB7ECFBEEC23621" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL23</accession>
    <name>A0A9P6JL23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL23"/>
    <dbReference type="OrthoDB" id="3170343at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="19435" checksum="B4832AB9C492EF5D" modified="2023-09-13" version="1">MSFNKQGNNSAATQGGDPFNTGSDFGEQNVRGGPGVGDSRNYSHNVLDQGSYDQNRDYGKASTGVGMDGNTRGTQTGELSDYSTSGQGMGTGNTRAMNLGHGNSTSGYGSESGGRSQAAGAGMGYNAAQDDPRGRSSQSEGNLGRQEKPSATDKLVGGAQKMAGKVTSNTGMYERGQEKTGDTGYTKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL82</accession>
    <name>A0A9P6JL82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_838895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL82"/>
    <dbReference type="OrthoDB" id="3439489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13197" checksum="2D127EA2CAE1EE70" modified="2023-09-13" version="1">MSLTNGSYYIKSTSSGNYIGRGNHEIFGGKTKISARGSFTAAIDNKLFAILENAPPAENWIINKVPQAGENKYIISKGDGSAGWVNGVSTQVSVTPLYVSPSFPPYYPPNEVWEITSYDGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLC3</accession>
    <name>A0A9P6JLC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLC3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="175" mass="20800" checksum="FAEBE82A456753B4" modified="2023-09-13" version="1">MNKLTKYLRDRKVQEAEVRFIHFGEVYLSKGWYTKTLDELDVIPATVVVKAEDPMETAVRMMRLENIYWELYCEHYGSEGTNRGQELHQQAYTLICEKLGPWSFQTKNSLIYLSRWDIASPKLARTLAERLRLVDMAQRSEIYYRSDYMLREKVALCCLRNQDYSDTVKLYSSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM85</accession>
    <name>A0A9P6JM85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_859515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM85"/>
    <dbReference type="OrthoDB" id="3364440at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="5">
        <location>
            <begin position="141"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="485" mass="53489" checksum="0E6966FD0E00BAC2" modified="2023-09-13" version="1">MSSNDLQHHAVPYKLPNSSKPQLSTIDVNRLRDSSIKYVRIQWVDLVNNIRYRVVPIDYFEKLLKTSRPGVSITKAAMGLIFITMADGFGPAGEYLYAIDPASVKMCPYALGHASVMGWFQEKTPTPGVDGHLAIEVDLCPRTILQRVIENAKRLSGVEFLVGYETEFILLKNTYPIEAVNQHGWSNSAAIPSGSVESKVLEEIVESLQASRVEIQMYHAEAAPGQYEIVPGPLPPLQAVDTLIHTRETIFNVASKYGLRATLAPRVFMDNCGSAAHTHISVHSSSSTPSSTSSSHPNLNHLESCFLAGLLAHLPSVLLLALPTTESFKRMMDGAWSGGTYVSWGVDNRETPVRLCNAGSPQARNFEIKTHDGTANPYLSLAGFLGAGMEGVLENKECTIEDCGLELNTSAALLGEEKRKEMGIKDRLPLTWEAARKTFEVSELVDSVFGKEFKQKFLSTNKTLREQMSHGLSNVEELKKYVENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMH4</accession>
    <name>A0A9P6JMH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Calcium-transporting ATPase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_859001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMH4"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000193">
        <property type="entry name" value="Plasma membrane calcium-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="825"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="858"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="899"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="952"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="991"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1026"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="9">
        <location>
            <begin position="41"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1068" mass="116052" checksum="53DFD2C6062D3E91" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNK1</accession>
    <name>A0A9P6JNK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_444601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNK1"/>
    <dbReference type="OrthoDB" id="3061721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="33969" checksum="6CECC5355904DCA9" modified="2023-09-13" version="1">MSSPTPQLKESRLPAELEREIFEIAAANQDIQTGLKLILTAKRVREWIEPTFYRVLIKCTDVPRTSPFLKHLHLENISPIERQKLSYCHCLLLQSISVEDAVNLLSACPNITDLAMWVLQGSYTPLGEILLSMKIQRLSVRINDVLRGFSSSHTLIGSPLSQALTHLDLIDLNSGFWDSAWKAFVALPRLTHLAVDGNNVVPTIEGMLNESKSIKLIVATSTTHAYLQGDLSNGESTSKWLGAWDVRFIHFPYPEGPISCWVEGTKGGEDLWVGAEKAQSNRIEQLKAKKESTKISLVEKKMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNZ6</accession>
    <name>A0A9P6JNZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNZ6"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="226"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="296" mass="32143" checksum="9C689883BB61F28F" modified="2023-09-13" version="1">MSNLDTPTISASATHDFSKPLRFLIFGGTGPCGILLIRKALQVYSNSTVIVSARSPQKIPEDLTFNGRVKIVTGKLEELDKVEKAFEAVADSELHKQLEEPPSYDGATQPNTTLRSSKVDVILSALGPPVLKGFSYPSNHPIATFYGNLIDIMFNQGVKRLIVMCTASHPDPKDKLSGNPLTSGIVTIVKLFAHNAYVDFKEVGNIIRRKGGEAEGESSSQSGVPETDLKASKLDWTLVRVPVLTNQDKEDTFAGYVGDGKTGNALTKKAFAAFCVGEVEKREWVRKAPFICTPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPF8</accession>
    <name>A0A9P6JPF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_895048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPF8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040304755" evidence="2">
        <location>
            <begin position="22"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="10005" checksum="21F47D168B5330E0" modified="2023-09-13" version="1">MLSVPKIVAVFAVLFVSSSIAAPVPKRSTVLKDTKVDIKSTSGPSEAAPSPLRRNCDEHKEGNVLDDILDPLLCDYLGGGPSPIAPVAVGGGGDKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPN6</accession>
    <name>A0A9P6JPN6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_750921</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPN6"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="13692" checksum="FC217CAFE1835D6F" modified="2023-09-13" version="1" fragment="single">KSGKAAGAEPTGKSQSRSSKAGLQFPVGRVHRLLKKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKHRIVPRHLQLAIRNDEELGKLLGDVVISQGGVVPHIAPELLPTKTGKGKKESQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQG1</accession>
    <name>A0A9P6JQG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_852411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQG1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF425">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="5">
        <location>
            <begin position="70"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="62232" checksum="312B226EA0687D98" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRB7</accession>
    <name>A0A9P6JRB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_834981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRB7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="21912" checksum="A5AC8719B1E8D5B9" modified="2023-09-13" version="1">MHYFLQNRTNVRVWPPLQAGPSFDFASQLEVAILEEVNKFDGIEQDLPNRSHRRRRFQRNEKILLEGHVPSPNVLSDILKRSNPVVKGLNLPALPATSCGYLATNLSDGQTSKVPDSLESLAADGFDYISWKALEPRPFTTKEGIIFGDMVGLPKDPGYKAACDCLYVKLEQVGSQLPEEFWGSCCQRGVEFGWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRW5</accession>
    <name>A0A9P6JRW5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ubiquinol-cytochrome C reductase hinge domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_851855</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRW5"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040189320" evidence="10">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="11">
        <location>
            <begin position="53"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="12795" checksum="D14BB2A61DB1CAA6" modified="2023-09-13" version="1">MSSVITSFLSSFISTAHADSEEPESRPPAETTSEEPKEQEAKEEEEEEDEPEDTHPALREDCKQSGKCAALTKHFEHCQEKVQGGEGFKGEDCVEEFMMHCVDNCAAPKLFATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRX3</accession>
    <name>A0A9P6JRX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_189471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRX3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040383169" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10262" checksum="537C3AEF1EDC0140" modified="2023-09-13" version="1">MNRRTQLTRAFLFLEFLTSILASLDRFACRNGNLEGWDKEPAQPSPMAGYLIVVALSKRAEILHLKGSIAAAVICKLRAFDYLALPLGRGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS42</accession>
    <name>A0A9P6JS42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_849882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="529"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="562"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="690"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="592"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1136"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1701"/>
            <end position="1733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1784"/>
            <end position="1812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1150"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1852" mass="209822" checksum="75056CE652141B43" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT68</accession>
    <name>A0A9P6JT68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_903297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT68"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="38458" checksum="B538B21E79A25F8F" modified="2023-09-13" version="1">MAAAYQWIQSSPVEVKRDIRLFSQIAFVTLGVMLWDVLGNLSFSFSIMRGRRRVTSILYFILQLCMILHPLFVVLSVNEYSGVSCGSRTWLSKVFGLIAVVCSSTMFLLRTIEIWGHGVTTMGGLGLPLLLQIGLWIRDLFPSKRTNIGVPFCDFIRTDSRLTLILTFYYSSLLVFMFFGLSAFKLVSFGRGKTVNRLFIGEGVIYFLPAALAYLAQAVLPSMHRNPVFGILGYPLSVVYPALCACLMYRGITDLGVDPRRPPYTSGFTQPSTNPQFVFASTPARGTPVGSPGLEGPSTSPLVSQDTELLSMDSRELNMKIDAELGIGQEGNQRTAATSKYPRFMKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTI8</accession>
    <name>A0A9P6JTI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_847830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat striatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTI8"/>
    <dbReference type="OrthoDB" id="727118at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013258">
        <property type="entry name" value="Striatin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08232">
        <property type="entry name" value="Striatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Striatin N-terminal" evidence="8">
        <location>
            <begin position="46"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="434"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="489"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="693"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="111"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="399"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="774" mass="84830" checksum="19EC1C5DF173E154" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU66</accession>
    <name>A0A9P6JU66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal hydratase-dehydrogenase-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_880662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU66"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05353">
        <property type="entry name" value="hydroxyacyl-CoA-like_DH_SDR_c-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="598" mass="63462" checksum="EDFABF2970A56E11" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUE3</accession>
    <name>A0A9P6JUE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleoside phosphatase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_586215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUE3"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046036">
        <property type="term" value="P:CTP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006256">
        <property type="term" value="P:UDP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24039">
        <property type="entry name" value="ASKHA_NBD_YND1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF121">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATASE MIG-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="681"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="681"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="196"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="771" mass="84521" checksum="CB296B3BA89A7E69" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUW2</accession>
    <name>A0A9P6JUW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_842883</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUW2"/>
    <dbReference type="OrthoDB" id="275748at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000286">
        <property type="entry name" value="Putative pre-mRNA branch site protein p14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13832" checksum="D56494F5B3255B61" modified="2023-09-13" version="1">MSITRPTAKLPPGANRILFVKNLNYEITGEDLYDLFGRYGSIRQIRIASEQKTKGTAFVVYDDVMDAKNALDHLNGFHLRERYIVVLYHMPAKQDAAAAKADLAKREEELAQLKMKHNIGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVB0</accession>
    <name>A0A9P6JVB0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVB0"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="640" mass="73382" checksum="9D8B67615588D77A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVB3</accession>
    <name>A0A9P6JVB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVB3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="365" mass="40526" checksum="8CF1E9210DF19A2E" modified="2023-09-13" version="1">MDGYSAIQIDLLEAPWSLDEVMKEVKGKKVICEENLRSKMSPLTEETLGALEAMETGCESVVKMMSMKVFTLEREIVALRENLAQKDREAMTKGEELRVLQDNYDNLSALSSISAVKTETSDVSLMQDLFEENSICAELTVNLEDANREHEEKLENKVDVLEKALKREVARVEKMKIIVEAWQREALSAQSRLDKAQFSFTFQLEEMERLALKCVRLEQEAQQRATSSNQAMGALESCDIEEFMAKWAPSQPAVASRAGLVADQNTFKLLTPHIFNPSSIAQAGTSTVPPVAQEGGRAKGTKNKKTAASTKRGALSQGAKLKSTVQAKPPRPRPPRLRQLTGGEIEFRPPYKKKRGPPPEDTTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVH1</accession>
    <name>A0A9P6JVH1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Pre-mRNA-splicing factor CWC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_902655</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM CWC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVH1"/>
    <dbReference type="OrthoDB" id="10251848at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000249">
        <property type="entry name" value="Pre-mRNA-splicing factor CWC2, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="16">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="159"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="13">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="276"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="358"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9533973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="43628" checksum="4CE39AF604CB3F85" modified="2023-09-13" version="1">MSTEEIEVPPLPPRIPQAPRPPKKLKPARKQVKAGDVNKQETVQTGKEYNIWYNKWAGGDREDSYSNKTKSQSRCHVKTDSGLTRANTTGMKYICLFFARGCCPYGWECEYRHTLPDETETGAAGESVPDTSKDCFARDKFADYRDDMGGVGSFNRQNRTLYVGRIKEVGTGPETEQVVVRHFREWGTIEKVRVLQYRSVAFVTYVSELGAQFAKEAMACQSLDNDEILNVRWATEDPNPVAKVAEKRRLEDMGQEAIKSKVDMSVVDAMKAVRDLEDGESYDPNYDDVQVEEMDEQEDGDQRDSKRRRLLLEQGDAEDFNQRSQTLSNASLPPNHNPTALLSADTLEGLKYFAEIRKRHGAPATAPPRAPPPSSAGLGLADYGSDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW41</accession>
    <name>A0A9P6JW41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Vesicular-fusion protein SEC18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_781386</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW41"/>
    <dbReference type="OrthoDB" id="9982946at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19504">
        <property type="entry name" value="RecA-like_NSF-SEC18_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000026">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000166">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000187">
        <property type="entry name" value="Vesicular-fusion ATPase SEC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="14">
        <location>
            <begin position="79"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="321"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="602"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9534125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="816" mass="88747" checksum="0D3275B3BA47D6DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC20</accession>
    <name>A0A9P6BC20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6830 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158208">
        <property type="protein sequence ID" value="KAF9521249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC20"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6830" evidence="1">
        <location>
            <begin position="59"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="27833" checksum="2E636A3768E3B5CD" modified="2023-09-13" version="1">MHKIGGFHLSGNKPATFLLNKVHKHHGDHHRYVPNLLELFKSWLGNNELLDNNRIYLGLFQQVLVWESIRLQHASSQDERLLAPTQTVEAKLPSLEWPHGKYDFVVVWSDSVPGQSDVLEVHRIFKPDFKNLLFSVSANVNALDQYFLYGMQMSFKGGLNGHRARDESTDMYILDRPEVPRWRILPASNVQFRVNLIPRFGSKATAELKSNTVNFRTESFLLNFFGEDDTFHSILSREKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E068</accession>
    <name>A0A9P6E068_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158143">
        <property type="protein sequence ID" value="KAF9521301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E068"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="18268" checksum="7FC7032E7DD79659" modified="2023-09-13" version="1" fragment="single">IALSKHSTSNNTQSAVKQGEDLPDVMYLQQDNQQQEQQKSETAISDHNQYMNGHRQYMLDQRDQPDPNYSDYLDMHRQRMLDQQNKKPETEATTYYQNLAQLATNTKKDQSSNKRNLDASASLTSDMDSVSKRPRLTEDLEGFEEQNKSDADSDQMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E124</accession>
    <name>A0A9P6E124_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158065">
        <property type="protein sequence ID" value="KAF9521437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E124"/>
    <dbReference type="OrthoDB" id="3052816at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="855" mass="96722" checksum="676FD504F33DA968" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3A4</accession>
    <name>A0A9P6E3A4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_739862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157999">
        <property type="protein sequence ID" value="KAF9521710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3A4"/>
    <dbReference type="OrthoDB" id="3251057at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="284" mass="32201" checksum="02CFE8528A7C8572" modified="2023-09-13" version="1" fragment="single">EADIAAVEEAELEEQVQQNDDGQIANDESTVKSIRGDAIQEMHERGVYMTTEENKTVLNIFPKVSGLAHRVHDITTLNKHFQELVRTDQELQSTKRGLAQRVPTCWNSDFDCIDSHLHFKAVIQGMTGVTDLKLKAYALSEDEWDLTKDLQEVLKVTFQRYHPFFSQADIPLVVDVLPALFQLRDSMDLVVNDAPPPTPAVLHIAAKAASLLLDKYLNKIWECEIYTVAIVMCPNRKLQWFKDRGMPPSIIKEIKSIVLAVWKDKYAPMDNQQLADATDKAQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3C7</accession>
    <name>A0A9P6E3C7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_887841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157990">
        <property type="protein sequence ID" value="KAF9521771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3C7"/>
    <dbReference type="OrthoDB" id="3219582at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="894"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1019"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1200" mass="129710" checksum="DFF70E72E7760F66" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3G5</accession>
    <name>A0A9P6E3G5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_887835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157989">
        <property type="protein sequence ID" value="KAF9521788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3G5"/>
    <dbReference type="OrthoDB" id="3016965at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="52624" checksum="CE003088C5A6EE0B" modified="2023-09-13" version="1">MYEFEVQSRQTILKIEALCHKLLGIDHEISLKRQELEVLTSIRSPITRLPTEILSSIFEALVTLEPGCFNAQHRLIKACKLWKHLVLENPIFWRTFKAVFPYHTHHIGTIDLKYLKLLTGLSRVINHIGRKLPLNLLIEDPNTEDEVDSEDESNASVPPLKIQDWHAKMVDLFRDPIWIPRFTYLGSKKLSNLVFLNIEYEELQAASSFDQPTITLTGLEHLAISSTFDLTLEDLTCMMESKLLKSLRLTAISGTFAFSSPETPLAKFIEQNSTLFSSLTHLSLIRIKILEIDFFSLLYNLLLLTHLELLYGAFGRGRIEDGVFYIQDKRIVEFLTVSDLLLNQDPKLEKPVVPLLRSIYLYDGQSHRGIYPGTQHLARMAISRCLWAMQLPQNHVLSRSSDEEEAQRSFEGSPFQLVLRIEPMRFRMVRRRMEDAIGALHRRLFKAEPQLSNSATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3Q6</accession>
    <name>A0A9P6E3Q6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="3">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_840860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="3"/>
    <dbReference type="EMBL" id="MU157972">
        <property type="protein sequence ID" value="KAF9521947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2507344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF154">
        <property type="entry name" value="RECQ HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="1174"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1371"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1371"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1390"/>
            <end position="1406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9521947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1406" mass="158995" checksum="6EA56282EECE935C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3X0</accession>
    <name>A0A9P6E3X0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157968">
        <property type="protein sequence ID" value="KAF9521994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3X0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="198" mass="22341" checksum="F988535B9F0AF9AB" modified="2023-09-13" version="1">MSEPPESNEDQISVENDQDDDFWENQGDVGEGWAGNIQQVEVASGENEDRQETIEDNKYATEADNKDEDMGGSDCFQQNQAEVDEQADHPAALEALDNNEDQDEGVDGESSAGDRSGAYNKGPSYSQSSDKIENNNAEDDDPDQSKWDKYNEMEEAEAEISGWQQLLEFNEMLEYEDGGDPTLQDVHDIFRRHKLFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E415</accession>
    <name>A0A9P6E415_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_887710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E415"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="63716" checksum="5F6FDAB1388EB425" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5K7</accession>
    <name>A0A9P6E5K7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5K7"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48722" checksum="2C2DF249B265ECD6" modified="2023-09-13" version="1">MPLYRCSLAGCLLAGLRGPSGTCMACSRRFCVEHITASSLHDCPTYESDPRAVDDMAEKNLQAELHELAQRLNLVELARVASSLRNGQGCTIHELDDQYLRTLPRGGMNIHLDIVFNDGVEWICRIRRRSASIQDLPLDAQDAVVLSEAATLLFLANQTSVPVPRVFKVVPPSTRDNLVGVGYLLMEKVAGKPMDWSSLNALSKRKVLEQLADIFHSIYEHPFPLIGCLHINNHPLAAFTSASAFSISHLVAEGALSQKEDGSTGFLGPFTSTCEYLKASVASNTLCVSSRESQTSSISHYLALEKSFNRLASRYNFSATKPENFYLRHMDDKGDHILLDDVYNIVAIIDWEWAQTLPEPLAFSSPLFLVDVAAYYEGQDGLSEDERLFVTVLEEKGHATLAKCVRNGRLAHRLAHLLDTDSDSGDIQIHWESYNRLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Y4</accession>
    <name>A0A9P6E5Y4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 1</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">E2 ubiquitin-conjugating enzyme 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_863386</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Y4"/>
    <dbReference type="OrthoDB" id="9993688at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14311">
        <property type="entry name" value="UBA_II_E2_UBC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000037">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015368">
        <property type="entry name" value="UBA_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09288">
        <property type="entry name" value="UBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="8">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00077197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="24012" checksum="9EAC46371C37FCAF" modified="2023-09-13" version="1">MDARLRRVNKEIADCKNDKSSGIRIDLVDESPFHLKGSFPGPQDTPYEGGYFEVDIVIPESYPFQPVKMKFITKIYHPNVSSASGAICLDILKDAWSPVLTLKSTLISLQSLLCSPEPSDPQDAEVAKHYMTSKSSFEDTARYWTQIYAGGPGPKEKSDGKDEVAIAGLERAHVDRFEALGFQRGKVIDALRRLNYRGPNVPKIPDDRVVEELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E678</accession>
    <name>A0A9P6E678_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E678"/>
    <dbReference type="OrthoDB" id="3039255at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="464" mass="52504" checksum="02B1B32021E1E341" modified="2023-09-13" version="1">MDNLPPELWYHITRFISSSELWKLRRINHFFQEAAYDRRFKVVTVHIGDLEKMALKGDPFYLTLRARELHFQYGGLHGDRTQASARTPFSTSIAACLKMASKIQDHLLRRHISDEVVNSSSLQAGAGAINASQILTSFKNVQQVFVHGIGNEATRADLEASQLDMLSFAIRSYGMNLTTLSLQIPRQEHFLQVLTSLSTLPRLPHLKRVYLTLYPSSFGDNANFQSEMKYAVVPFLNTHRETLTSLHLLANSYIRGLDLSFLPFLARMPHLRILKLYLLLCLPSAAQTVKTLLKKHTYRLESLVLGVVGPDDIDHQYTNLSLLYTPLPFLKHIEINEDIRIARSRAANSLPALISYISSYRKTLHTLRVSGRKIIYTDMERLASATWPKLVSLDLHLLTCSPEFFDDLAQGFPALQDLSLLVYSFLGSTVPSGALSDDENRAEAIQHPVGRPLLPLLRSQSDCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6I2</accession>
    <name>A0A9P6E6I2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_951572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6I2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="309" mass="33695" checksum="7E340963BF2D2551" modified="2023-09-13" version="1">MLFLWRLCRCRSQNRSSQKFNLNLILKHLESVVGAPSSLNPNDSPELKKKTKRSRLHRKASTSSNDNHAYAGDTDADMEESAQNSEDEFFNPKKNRSSAAYTFFGEVPNASPPRPDLHETVVARQPSAHPTSSAPPMIATKRPRDIPPHVLAAFGRQKPPFRGTPMTPENHPLSAASTKTNQPSATQPVEQSQAPSVSARSSTQPAIKAPSFSAPESAQVSSSSKHLKATSSKQPEASSSTGHRRPEFHLPDLPADSPLLNSTAWRRSQDHQEKATERKSAPSRNSSPPPAMVSSKNPFSKKSAKNTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E781</accession>
    <name>A0A9P6E781_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_657306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E781"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="256" mass="29273" checksum="F6B8CEDABB97D43C" modified="2023-09-13" version="1">MESWSKGHFSTITEAISFSSQGTGNKFHSLTFRKDAVNKHERASQTSAFLVNPGFPLLQMDQPITLLFEGDWRTRSMPWPNHDSKSYPLPHTRRHLFVHLYLPHLSDPHRHPPSLHSSLSLLPHTFSPENPAWPHQNSCLIPSRLENDYMLAFRHSKAWIVTVTMSKNTSWAHSEGSDSKLFWIWYDWAEGLGLWMLGMMFGMMFGMMLGMMPLIGRRFVVGSQNMPSSLLGVTVTTSSFYIRWCTPPGSPGRPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7G2</accession>
    <name>A0A9P6E7G2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_839439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7G2"/>
    <dbReference type="OrthoDB" id="3184970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="285" mass="31234" checksum="BC8C3D024D132AB6" modified="2023-09-13" version="1">MADPSTEDTDSKVDLGSSFNDPTADVSYTSSDGVVFELHRKHIEVNAPNLPLPDVPSVNDQDGSKNPPIALQESAVVLDILFRFVRASTKDKKTLPPSLSDIIGPVLFEVAEASEKYGVVGALNVCLIHMNQMVTDGRYPLEIVNFSDRHGYEALENAAALLSLSYPYRDLVTKLSGSDLLRRFLLFRDEFANIRDTALSIMDKADCSSSGCQAIISLKLIYLSAVTENLANARSSIPHTAAACVYDLRYATSCKTMIYEKFSNLFDPELSPVKVLSDITLETTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7T5</accession>
    <name>A0A9P6E7T5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_820634</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UTP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7T5"/>
    <dbReference type="OrthoDB" id="30195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="253"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="565"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="443"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="505"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="713"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="778"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="794" mass="84921" checksum="14645154FD1BF40C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8M6</accession>
    <name>A0A9P6E8M6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8M6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="375" mass="40853" checksum="6AC606DCD8698BDF" modified="2023-09-13" version="1">MDPMNAPVLEWYANSSLPNLPNQFTRSTGSSTAQDHVSITNSSFDCDYNFNFNGLPPTLDFFGSFQPCFEPSATHQPQPQPNIQAVSWYSNVSFSPPASPVGSTWSDSSVGSSHIGVSPILHDQSMDLPVPLNATSGGEGLPYDSQPEPALLNTQPPPKSSDGGWPSVINKALTSLSLQPTIGASSQQAASATPMPQTLPQPQDSTFPSNSLLLGPCRQTPSTSRKSRMMDPIKRQSKTTNPPPTRPRAGSGILGLCQWQTKIDPLNPLNPNSNSNPNATHHHQHHHQHLHQHQHSQCGIFLGDMTNGELLQHLKDFHAEPIPSGKKLIKCRWRGCRASRATDGVYHGSSFKRHILTRDHVRDLDPAFGLDLIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8T7</accession>
    <name>A0A9P6E8T7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_860925</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8T7"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFG/EF2" evidence="7">
        <location>
            <begin position="329"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Elongation factor EFG" evidence="6">
        <location>
            <begin position="447"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9524580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="611" mass="68064" checksum="D292BA31325CA2AE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9N9</accession>
    <name>A0A9P6E9N9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_897254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9N9"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052279">
        <property type="entry name" value="EngB_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46498">
        <property type="entry name" value="GTP-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46498:SF1">
        <property type="entry name" value="GTP-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EngB-type G" evidence="5">
        <location>
            <begin position="59"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="26720" checksum="B2A6C3EFCC7F572A" modified="2023-09-13" version="1">MLLTRHTKGVFWRQNGVYHVCNGSRRLHAPNAGKILDFTQTSEFLAAAGAIPSIPKSSGLPEIIVTGRANVGKSTLLNAIVQRSSNKLMNTSSKAGHTKTLNFFSVGASPGKLILVDAPGYGSRGRPEWGDLFDHYVQSREHLKRAYILFNAKHGLNGHDIRMLSHLSQLLMNERGEQRFTLQAVVTKADTVPVAELQSAIAKIKEDIWKAAPLCLAPIVTSAGMAPPFGIQTLRQNIAGACGLSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAM3</accession>
    <name>A0A9P6EAM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAM3"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040363748" evidence="1">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="69" mass="7897" checksum="6945F5A14BA0A4F0" modified="2023-09-13" version="1">MTFSSVWITIASLIYVFDIEKETNEYGSPIEPNPSYVSGLLFAPETVPCRIKPCSKEFEKLIEAHNNWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAM8</accession>
    <name>A0A9P6EAM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAM8"/>
    <dbReference type="OrthoDB" id="2741288at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="35141" checksum="3BC92407D5B95857" modified="2023-09-13" version="1" fragment="single">VIAALRAKGLWQIVLGNDPKPTVHSPTGTNAAEIKEDTKDLLDWLNNNDKANGLISANININLRSFVDKSAKTTWDNLKVQFDKPEPVNIYNLFTALCAWSFDARDDPDDQTRSWTAINDRLVTAFHAYSAQVQTFFQTKEEKDLNVSALSKVFVTVWQQRQGARAFANKLSAVPRRGPDPQHRPAKLIPDGNKPGYPSGSPRNGQAPTSGSFQPHQVAGQFRKTKHSKRAGKKKSKQAHDAHFMASNIVDAPSLAARLTSPPPKRSLAARLSSPPPIQSYNTSTAVLPKVYGIIIFGDSGVITRRAKHTTAAAMKQEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB17</accession>
    <name>A0A9P6EB17_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB17"/>
    <dbReference type="OrthoDB" id="2981416at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="24819" checksum="8EB251FD8D31C198" modified="2023-09-13" version="1">MVMAGQRYCTGVPWQKSFQDAVKQTGANGVTGLKLMAEGIGRGPVGMLAGVAKATAKAIIDAKKTTKKTSQKSAKRIATKSPKRTAKKTPKKTAKKSVKHAAKKNVKHSAKRSVKHSPKKSTQRNARKSVKHSPKKSVKPSPKKSVKPSPKRSVKPSTNKGGKKKRELADENDILNRRDFEIVARDEDFSLVERGEYSTFDLVVRNEDGSLNVRQCEMYNGDTSCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB98</accession>
    <name>A0A9P6EB98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_511530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB98"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="17864" checksum="53BBBB462A457FDE" modified="2023-09-13" version="1">MLSPRKVSNESRPYRSSLRYIAGILHGILQAHETKGGSSQLREVEIELSMGLEAPSLVLVDFEVLAHVSTTVDSFSSPTVDSSSSSSASSLRHKPMATIDSNTPFPTPLPLPMITLSIAKLASAEQNTFDQSISIKSILADDQKNEALVSLMRDGKIRVVGRELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC21</accession>
    <name>A0A9P6EC21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC21"/>
    <dbReference type="OrthoDB" id="2367075at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="33704" checksum="AFCE32E2EEF3D2F2" modified="2023-09-13" version="1">MTASQQQSTDLDSDPIIVPTDGASVTQRHPLYYIELVLFKVDTTLYRVQKHGFLYSNPKFFDRFNVPSDNNSDASDSNPIELNGVTSQAFEGLMVVLYPMNGNVPTYEAWLGALELATQWDMPDIRTRAIDALTNLHQNGSSTNTEIINLAKKYGIKTWLKDEYVKLVQNHSTRLEDLVGLLDNETLMRIFATQSYLFQDLTPPTTEASIICNNCTGGHGFTHCDKCCYQKGRYSTSTRNCDNCRNNKAWVFCELYCPRQHKPQVGLQDRAKVEAEIDRVFTAEFSFMGGIATVGSDPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECS3</accession>
    <name>A0A9P6ECS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Muskelin N-terminus-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_884853</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECS3"/>
    <dbReference type="OrthoDB" id="10052615at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052456">
        <property type="entry name" value="CTLH_complex_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010565">
        <property type="entry name" value="Muskelin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15526">
        <property type="entry name" value="MUSKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15526:SF5">
        <property type="entry name" value="MUSKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06588">
        <property type="entry name" value="Muskelin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Muskelin N-terminal" evidence="4">
        <location>
            <begin position="14"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="756"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="761"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="790"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="819"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="860"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="885"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="933" mass="104125" checksum="1324C19966E34D70" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECS7</accession>
    <name>A0A9P6ECS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_884687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECS7"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="202"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="753" mass="85207" checksum="44DD573FEDDBE7E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDI3</accession>
    <name>A0A9P6EDI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDI3"/>
    <dbReference type="OrthoDB" id="338854at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="28505" checksum="74FC75A6B632AA14" modified="2023-09-13" version="1">MANSELARKRGKNLSNANLRLSGYPLPQMDQSQTGVAFPAPAPDSAYTLLDSPLPAMTPVMSATHRARRASAAEKVLEQLRSRDIQKSGSVALSSPRASWLNFQQHEPVVSATTATTALVSPNTSTSLSTVSASVSSTITVMPSSTVQDSPTKGPLLGRSEGRRLSLTTPSVPPSSPVLSKMTLAPARTTRPSRSPSVGQIGQPLIAPAGVPPLQPTIPPDMIPLMDGDHHTDELSVRFEVGWPLLEQWLVTIGGGAGDGDYGRVAIIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEI5</accession>
    <name>A0A9P6EEI5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter transmembrane region 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_907450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEI5"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF67">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="727"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="805"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9527631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1113" mass="120171" checksum="D839F48A471626DF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EES1</accession>
    <name>A0A9P6EES1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_895248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EES1"/>
    <dbReference type="OrthoDB" id="3266934at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040230191" evidence="3">
        <location>
            <begin position="28"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="636" mass="65343" checksum="2EDB07E27340193D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EET1</accession>
    <name>A0A9P6EET1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-amino-acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_793251</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EET1"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="109"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="55"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="376" mass="42144" checksum="DBF09CC269CD942C" modified="2023-09-13" version="1">MSKPSAVAETKKQVIVLGAGVIGLTTALRLQESNDYQVEVLAELFPTDLKNINYTSQWAGAHHVSTQERTPDVEWLTFQEMWKLSEPGSLAEHCFMRIKEHEYFDSPVLQTEVMARMPNFQKLPQSDLPIGAEDGYSFDALTIDVPVYLNFLLSRLLEKGGTIVRGRVQHISQVLEAGTYPFKDHSRLVGRNEPIVPPHAVFVCLGLGARFLGGLEDHDMYPARGQTVILRAPWIKSGMAFHGDGANRWAYVIPRRSGDVIVGGTMGINDWYPKARPETTHEILEYALLYCPELVPLDFRETERLPLVDDLKSIIVEEACGLRPMRKGGPRIELDYLNTRGRQVPVIFNYGHGPYGYMASIGSANMCLKLLKEAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF72</accession>
    <name>A0A9P6EF72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_907301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF72"/>
    <dbReference type="OrthoDB" id="5428495at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF147">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="14"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="479" mass="52509" checksum="471A9039A41758FD" modified="2023-09-13" version="1">MEYSNSCGVILKFVVVGGGLAGLATAYSLKKAGHDVLILEKSDGTQRSSGSVPSSPNMTKVLKSWGLESTLDTIAQACTRVNFLHAESGEFLGALTAAVLDIVKKDSVAGFVFLQHCQLHDILLELCLQEGVEIHYNVSVSALEPEEGCIMLEDGGKICADLVVAADGFHSILRSYVTEEDPEEELESEAKIVLFRTTIPIARMHQHQSLQGLGTLEDWDWWMGDGYVVRCSVTNDGQDYTVVLVHPYHGPVDSNTMEWRQAPNTKSYGVDITKLDGRLRKLFRLSNNLTARVYTSPRAAESLVCPCSRVILVGEAAHPVIPGGYHATAMGFEDAETLGSLFARIQDRDQIARITTAYDEIRLPRATYVHEYEIGYQGVLKAAQGPVQQIRDQRMRQLGAFNTGAEIDEDMILEGWGGELMLITHDASEKVEDWWGQYGASIMKPASTYSLPDVQSMRISIAENTTSASPSVSCFAIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG33</accession>
    <name>A0A9P6EG33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG33"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="132" mass="14723" checksum="0053318B0E0012B2" modified="2023-09-13" version="1" fragment="single">MPIPRAPFPSFALVLAAESSQSDSQATSTATLDTGEIRERPKKDLMKTYDPRLDADNWNMRTMDTEEKSETDTIFEVYDDEGKEYEAISDRSTGVRNDCCQKGARRARRRCTGGLVSWLRTLACCGGDTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG86</accession>
    <name>A0A9P6EG86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_883510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG86"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="79"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="617" mass="70586" checksum="3761FB21E8AFD60D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGZ2</accession>
    <name>A0A9P6EGZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGZ2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="10907" checksum="5AC249D246B87329" modified="2023-09-13" version="1">MIVLLQNLWPRSGGSINFSLVHLGGLLAFSASKPEKRVFQPGCSPTICQFGLTREGSNDYFCITSLETGKNFTRCASFVCCGRRIVGRKRVCRRAKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH22</accession>
    <name>A0A9P6EH22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">H-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_882899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH22"/>
    <dbReference type="OrthoDB" id="5419324at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098636">
        <property type="term" value="C:protein complex involved in cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046871">
        <property type="term" value="F:N-acetylgalactosamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070492">
        <property type="term" value="F:oligosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2080">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052487">
        <property type="entry name" value="Galactose-binding_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037221">
        <property type="entry name" value="H-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019019">
        <property type="entry name" value="H-type_lectin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46938">
        <property type="entry name" value="DISCOIDIN-1 SUBUNIT A-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09458">
        <property type="entry name" value="H_lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141086">
        <property type="entry name" value="Agglutinin HPA-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H-type lectin" evidence="1">
        <location>
            <begin position="115"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="H-type lectin" evidence="1">
        <location>
            <begin position="209"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="277" mass="31664" checksum="52F5DAB3FE5F7A74" modified="2023-09-13" version="1">MPVLCEFDTRSVHPPENPFADTQGTVHFPQTFVARPRLPHGLRELNMSRNANISVKSTNMYYTTEWADCHITTWDDAALYSGIDSIFVLTPADVEFQTGEHMRTPMIDPNDPPSARVDFREPFASPPKVVVFFNYLDLDKHHGWRIKTTATDIDERGFTIKIETWGNTILNAAQACWIAYPEDRKHIFSTSINTLEVRPTNKKQHQHNKTISFDGVEFWKEPDVFVALNYLDVSRRANLRINAYVDGVTSTNLNWHVDSWDDTVLHAGGASIIAFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHH9</accession>
    <name>A0A9P6EHH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">60Kd inner membrane protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_853339</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHH9"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="9">
        <location>
            <begin position="183"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="409"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="437" mass="47170" checksum="D11E5621A08A8CA8" modified="2023-09-13" version="1">MSLASSVGLSFRCAGLRLPARGARHSALQPLKSNLRTFSSGLQSRHHLIPFRVPTNSRNLSLWSSTKPTSQSASSPITPPETLVDEARTMLTGEISESTSASSLSGTPVEASSEVTPVMPPDVDLALDSIAALDSSSLTDTVLQHAGQLQWGDLSALGLTGYTPAGLIRWSFEVINVTTQLPWFWTIVAGSAFWRLVCVPLTIAATRNAAKLAPHQEAIKALQEKMNKVSTKNPAEKMKIANELSVFYKKHDISPLGAMVGLAQLPITLGLFFAAKGLCDLPLEQLKDSGFAMFPDLTVTDPSLFLPIAMTLAVNTQLMIGARDVASNLKPMMYFFHFLTVPGFFLMKAFPAGLLVSMITTTLLTTIQTIALRIPALRAALKIPPHIPQKAVPGSSPFAQIRELLSQSKPEDVKAKVSQARREAAKVRPSVQTPRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIC8</accession>
    <name>A0A9P6EIC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_905991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIC8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="279" mass="31063" checksum="9FC8C602C6D6CD6E" modified="2023-09-13" version="1">MRLPQLRCPVSKFYYANSDTRCSSSALILCETIAPQVYNETPWYSWKFADPTIEHQPGKSVTSGSITDQSKDVCSSRGEIAVSTSLVLRFFQSSRFVLSSFIVPCDGLKAFEYLDVPDNALASSSRLRSMTTSTSALSSKRSKTATHPRLPFYENRFNSPGGSTSFNTVRRYLSTGARNELLPPPLTSHSRPRTPNTISTKIDEQEFLDLADSLYKTSIPPNETEDYSDSGLLNINSTHFVHNGHFEQVEDNGSRNIVAGPEQLLSDHHSVKSNKTIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJF2</accession>
    <name>A0A9P6EJF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJF2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="98" mass="11163" checksum="733738D44239F914" modified="2023-09-13" version="1" fragment="single">VHCQRIICGYPLVFPACTTPMSQSTHGSRTGAKDAYFWAPKVACSWREANHIGQVRVTLVRLVQRWDLSFFLTSYHHHAVFLPPSSPSFLQVPHKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKU5</accession>
    <name>A0A9P6EKU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gti1/Pac2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_810090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKU5"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="547" mass="58886" checksum="2F750608BCF3FC78" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL86</accession>
    <name>A0A9P6EL86_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_849947</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL86"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="586" mass="66650" checksum="A65FFAA4E6614054" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELL7</accession>
    <name>A0A9P6ELL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_52441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELL7"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="25"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="110"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="250"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="36123" checksum="2EC2D81167FC650B" modified="2023-09-13" version="1">MTSESPKHENGSAAHSRSPSPVAHDTLTLRALVSTKDAGVIIGKAGKNVADLREQTGVKAGVSKVIPGVHERVLTVTGSVEAVSKAYNLIIGQLVTAAPSSPITPSSPSTHTSIRLLISHNLMGTIIGRNGLKIKAIQDGSGARMIASKEMLPQSTERIVEVQGTPEAIGQAVEEIGKCLLEDWERGLGTVLYHPGPSTENRRGHYSSSSYSSNTHSSRRNGDGVPRRSSPPPGSPNGPSSPSASQPPANLRTQNISIPSDMVGCIIGRNGSKITEIRRLSGSKISIAKTPHDETGERMFTIVGTPEANEKALFLLYNQLESEKERRVGREAQQQAELAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM80</accession>
    <name>A0A9P6EM80_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_904593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM80"/>
    <dbReference type="OrthoDB" id="2635672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="584" mass="65402" checksum="9430A1C0C48DAB48" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMA5</accession>
    <name>A0A9P6EMA5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_759744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMA5"/>
    <dbReference type="OrthoDB" id="285729at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="26455" checksum="7F61BEE1FFF91743" modified="2023-09-13" version="1">MANPRQRRKARSSSHRPVSHSKNAKRNLKKTPPIRGPKALQEAWDKTKTVRQNYARLGLAISLDPLAAGGSERQLGVCLDDEGSSRATTDAVEPSLSNVVPDGFGRLIRDDSGQIVGVEIDQEDNLIEVEDVDGVDSHIDPDVRQKWVTDLSQKTSAIGVTDVTLMKELEDISSVATGTTTLALPVSGVGARHVSIGELKYLQPLLKKHGGNLNAMAGDLRLNPEQKTAGQLRRALRSAGLLMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EME2</accession>
    <name>A0A9P6EME2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_105907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EME2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="71" mass="8138" checksum="4AE880C492EBEDA4" modified="2023-09-13" version="1">MSMLGRLITVLVHTGKALRVAHTNHRYSEVEAKPRRMSKTFCAEPTTLNSPENNIVLWVSWWAVGLSYPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMM0</accession>
    <name>A0A9P6EMM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_786706</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMM0"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040491217" evidence="11">
        <location>
            <begin position="17"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="516" mass="58086" checksum="484F2E08FC9578A0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW4</accession>
    <name>A0A9P6EMW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="10158" checksum="39F26D6E868CD171" modified="2023-09-13" version="1">MGHIASADHDQSPRLQITAPRSCTSRKRATPLSLIIVFWVGTCNCAFYTQHQDPAKFNRVMRHVNDARIIVQPPWREYIRVVQRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN64</accession>
    <name>A0A9P6EN64_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thiolase, N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_848094</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN64"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="47"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="299"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="423" mass="45168" checksum="A4368A44C59B5EAF" modified="2023-09-13" version="1">MLRLISRSSLNRAGSVYPPLLARAASTSSRTLPRGLSEVLEKKPDDVVITFAKRTAIGRAKKGQLKDTPPDEILYALFKASLERMSLDPSKIEDICVATCHPPSPLYISRAAAIAAGIPYTVPISVVNRLCSSGLMSIRHIAQAIKSGEISLGVAAAVESMSLNPRPTPEVVPAIEANQHAHDCMQPMGWTSEMVAERFNISRQLQDEFAFISHSRAEQALAKGIFASEIVPIEINGAIVSIDDTIRPGVTAAGLAALKPAFPKWGQASTTAGNASGVGDGAGMIVMTTRERAEKEDMEVLGKYVATTVVGVEPRYMGISPVYAVPKVLQMVGLAKEDVDVYEMNEAFASQFAYCVQQLDIPIEKINPNGGAIAISHPLAMTGIRQVATGLEELHRRNGQILCTSMCVGSGMGAAGIFVNERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENH7</accession>
    <name>A0A9P6ENH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_848382</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENH7"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000411">
        <property type="entry name" value="Probable Ste20-like kinase Don3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000092">
        <property type="entry name" value="Serine/threonine-protein kinase 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046409">
        <property type="entry name" value="PDC10_dimerisation_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048288">
        <property type="entry name" value="PDCD10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20929">
        <property type="entry name" value="PDCD10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="14"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="308"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9532120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="523" mass="58714" checksum="0702FA0763CEB13C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPE9</accession>
    <name>A0A9P6EPE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_847235</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPE9"/>
    <dbReference type="OrthoDB" id="2563978at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF6">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="221"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="479"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="694"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="804"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="892"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="709"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="727"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="743"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="922" mass="95862" checksum="6B942DBA104356E2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ30</accession>
    <name>A0A9P6EQ30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_903339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ30"/>
    <dbReference type="OrthoDB" id="3014488at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="40805" checksum="C25BF6709C01A042" modified="2023-09-13" version="1">MGYATGTAVRVIDIWNKLQSRPDLASARIVRLSHVKNIDSPLAHEYLQFIIVTNNVRERILVERTKADQFVFNGEWKMPQGNIGIRQRLYNLIHWVRNDLPLPLFTLSWEEANAPTFYQLAQVCQAIHDQAPKYSIPKGKHCYWFAFGVYAAIKLAHGGEEKVWPFSSARGFPTFLVPRGVLDFSQLKLLAAAFQENRAKTMDYLEESGPDVIEETLKVVGLVKSALEGDGILGELEEELVSQESEPTSIIDGLDIATTEREEPFENVSPEEMYNLSNFEQGHYALKEAMKQDPAAKDNIAIYREVRNARANEGRDKSKTILHVPANDEFGYSKIVEDAEGMDMAMEAFLGAILKEIGVAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ38</accession>
    <name>A0A9P6EQ38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_832174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ38"/>
    <dbReference type="OrthoDB" id="3352270at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="62348" checksum="84F52DF01A6A8D77" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQG1</accession>
    <name>A0A9P6EQG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isoamyl alcohol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_846407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQG1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040451357" evidence="3">
        <location>
            <begin position="23"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="131"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="583" mass="63388" checksum="40DF07595E472A0F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQQ1</accession>
    <name>A0A9P6EQQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQQ1"/>
    <dbReference type="OrthoDB" id="9996895at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF21">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="964" mass="105869" checksum="13B33C2A6F894449" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER07</accession>
    <name>A0A9P6ER07_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8021 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_902514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER07"/>
    <dbReference type="OrthoDB" id="3515051at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058334">
        <property type="entry name" value="DUF8021"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26061">
        <property type="entry name" value="DUF8021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040404029" description="DUF8021 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8021" evidence="2">
        <location>
            <begin position="155"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="28947" checksum="3CFEFFDDE136AFF3" modified="2023-09-13" version="1">MFRTFFVSALCAALATPTLAACTFSQLQNITAAYIAAQSTGKLPARISSATYTENFKSAHIQKGIISKALKIDHNRSLYDTVTCSTFTELIVASNSHPYVLGTQIALADDRTKIKRIDTIITTTGDWQFNATGTLYWSKQEDIASGWETIPEENRDTRAVIKAAADAYLDVFSDSAVVVPWGTPCAKLEGGLYSGTGEENDSCNTGVPSGTKIVNRRYVIDETVGSVDVFLNFGGDKGNPDSHNFRILEGNIRYIHTITHGQILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERJ8</accession>
    <name>A0A9P6ERJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERJ8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="6795" checksum="7D02DBF29246B2CE" modified="2023-09-13" version="1">MIQVACLRVVIPVSAISLRLVVTLAQTFLEKSGDIVGNSLKLLITIGLCCLETPGYVPSDERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESB6</accession>
    <name>A0A9P6ESB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESB6"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="63906" checksum="260BB68D1D2A379A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESS7</accession>
    <name>A0A9P6ESS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGT1 protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESS7"/>
    <dbReference type="OrthoDB" id="27237at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="873" mass="97652" checksum="4F654C07C2599E41" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETJ9</accession>
    <name>A0A9P6ETJ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_843306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETJ9"/>
    <dbReference type="OrthoDB" id="3263055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="170"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="331" mass="36250" checksum="6BCDA3E5801ABBFA" modified="2023-09-13" version="1">MSSNVAPMSVDTTMGAAYIGVMAAGILYGVSFVQTWYYFAKYPGDVWYIRALVASVCLFETVHQALITHTVYHYVISNYNNPDSLGEMVWSILLEVLFNGFIGLLVQSFLLLRVWRLSNNHLPLAIIIGCLILAEFGCSVAFTAQSLQFTTWGELEGLKGLSMAVNLLGAAADVLIAAALFYFLHTSRTGFKKSDTMISKLIAFTVSTGLLTSVCAVASLISILVSGHTLIYVAFYFCLGRLYSNSVLATLNARQIIRRIGEASDELSFSLQSVSKTAQRNVGSTRSANISIKIDTIHEFIREQRQNSDDDNADPESATTDKTLTELTPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV60</accession>
    <name>A0A9P6EV60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_753465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV60"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="10575" checksum="7156938B6CC42EAD" modified="2023-09-13" version="1">MSASGAGKKRQSPGGRSARMYLCDVEGCGKCFARGEHLKRHVRSIHTYEKPHKCPYPGCGKDFSRHDNLGQHMRVHKDFVPPPSAATVRKKSQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVM2</accession>
    <name>A0A9P6EVM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_24324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVM2"/>
    <dbReference type="OrthoDB" id="3360032at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040446508" evidence="2">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="26286" checksum="72144416E0DCDACF" modified="2023-09-13" version="1">MMFFHHLSAVFLLLCLVRNVVCNTEIRNFLAEQKENAELPFTQSWPTLGPHKRSAKLNATSAPLDSVLPQSICHSVARWTPSGRGHCPFEYWIVLNVDHTAWSGFDKFTLRASWPASNPSNIIITIFNPSELASATHRPSLVETTTRRKYARVQFVHSGVLTPSSNPMDSALRYTVPVIVTLEPLHLGFVPASVIPVVVAILAAIGAGYVLASRFNAFLRPIAQSIREERIMQKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVQ3</accession>
    <name>A0A9P6EVQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_779865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVQ3"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="217"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="542"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="585"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="554"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="652" mass="72548" checksum="A827DD9B42A1F2B1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIF1</accession>
    <name>A0A9P6JIF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_777383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIF1"/>
    <dbReference type="OrthoDB" id="3360976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="55" mass="6191" checksum="7A8F4FEF2892105D" modified="2023-09-13" version="1" fragment="single">EVPIVIYHRKHLGILSDARAASLEIFPQGQHMVDDIITTFVYIRVAEKSRPGACK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIS0</accession>
    <name>A0A9P6JIS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_822882</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIS0"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097039">
        <property type="term" value="P:protein linear polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF13">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="800"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="222"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="988" mass="112765" checksum="98A1C4A37BDFC14B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ34</accession>
    <name>A0A9P6JJ34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ34"/>
    <dbReference type="OrthoDB" id="69928at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN" evidence="2">
        <location>
            <begin position="125"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="388" mass="42189" checksum="4F5BE721AFE0AA7E" modified="2023-09-13" version="1">MAEGRVVNGNANKIAMSRALGAAFLHHQVEQLEKSVSSGGPTGGNWRDRRGNHNSSLGAGKRGSNPPGGKSPQKKKLIQDGAATIPSRERAPAGNRDFDRSVNTSPSSRRISAEEPKKEKDADIVVVDGSVLIHALYQVKKWCKDGREEILIVPLEALNTLDILKKGTSSLAQKARAASRILEAQVGTNRRIRVQRDDAFVLWDKINIEDAASTSPSTCPEWVRRIVCCARWELENPQEELKDSTKGKTEDKKPALKVVLAVLSSIPNTSPQINITALSAESPVPLPAPTIPHATRHEPRSTGILVSSWASRAGVTLLDIEPAMPGRGGGEDDDRFKRSRPRRPSTSEHTIPKTALVERPPAVMAMMEMVSQPSKVVRVLARGEKLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ58</accession>
    <name>A0A9P6JJ58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytoplasmic dynein intermediate chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_739506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ58"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000414">
        <property type="entry name" value="Cytoplasmic dynein intermediate chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001070">
        <property type="entry name" value="Dynein intermediate chain, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="476"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="644" mass="72364" checksum="9BD8D1A5954EDFF5" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ67</accession>
    <name>A0A9P6JJ67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_878155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ67"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="432"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="466" mass="50881" checksum="40CBB350A756325E" modified="2023-09-13" version="1" fragment="single">MAATALTTLASTTQPIVPTSRSSTSDEKLSVDKVDQASKEEKSVSHHGVPELIHGGPEEEETTYPDGGFWAWSTVVGAFLLQFTCFSYVNTFGVYHQYYVQNYLTNYTPSDIGWIGGIQVFFNFAIGALTGRLFDKGYFRYLTLGAIFCHAFGVFMLSLTHPNAYYQVFLTHGLFVGLAGGLSFVPSISITGSHFHKRRALAVGIVCSGGSIGGFAHPLLLNKLFSTSIGFHNGVRISAGMNTFLLIIAFFLMRTRPLHKSVGPELSIWRYFKEPAYLSFLIGGFFVYLGIFLPLFDVQLFAVTHGMDKTFAFYTTSILNASFAFGMVAPGLFRLIPIFGVLNLTTFFTLSSGVLIYAMAAVNSKGALIIFMILFGSLAGASLTTTPTMLAFLAKDPREIGSRLGVFYAIGGSIGLFSSPVSGALLTSDYHWVRPCIFDGTMVFVGGLFFGIARTLYAREHKSQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ98</accession>
    <name>A0A9P6JJ98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_910980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ98"/>
    <dbReference type="OrthoDB" id="10248542at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000014">
        <property type="entry name" value="Proteasome subunit beta type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="279" mass="31301" checksum="07AE3E1F7B7BDC56" modified="2023-09-13" version="1">MDHFPSNWGRPRNDAIDQYATYPIHSRPKDSFAEGVQRTQQPIVTGTSVLAFKFKDGIMMAADTLASYGSLARFKDVQRLHAVGNHTVVGAGGDMSDFQYIQNLLEQLIVDEISAQDHHTLSPAEIHEYLSQVMYARRSKIDPLWNSLLVGGFKDGEKYQPSNPRRPLPLTVYLRFLAYVDLLGTTYSASTLATGYGAHIAQPLLRKAVESREEILTEEQALKIMEACMKVLFYRDARSLNKYQVATITKDGVKISDSKTLDTSWSFAENIRGYGAQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJX1</accession>
    <name>A0A9P6JJX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_658265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJX1"/>
    <dbReference type="OrthoDB" id="125413at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="29"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="41829" checksum="E1C313A87BD4014C" modified="2023-09-13" version="1">MTSFPEEQLDSAKGYFPGFPGMTLQSGKWTIICKLGWGERSSVWLVHDTFQQIKFRAIKIYTVSDSKEVTALNELRTFRLSDIKDVDVVQLQESFKEGSHLCLVFMPHGVTVEILRKSNAAGGYVAVHIAKQIAASTLTALSSLEDINLVHGASDHIVVGDLEKEDIMAAQIDTGVEQLTKNGCSYPLVRSQPIDPKGSGTTWNEPPVDFAGKSRLLVNLGHGKSQLSHRQTSNILTGSAAQPTQNLKALQAMKMSKSVPFPPEVLLGRSIALSSDVWQLGWMTFLLLTGTPLLNQDTYAKSPIESLNQILEPPFLENCLLCNATLLKEDLEPTVTLLRSLLTADPLLRPTVEDLLDNRWMQQGDICICGACTADSVITEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJZ2</accession>
    <name>A0A9P6JJZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5648 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_821652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJZ2"/>
    <dbReference type="OrthoDB" id="9971254at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043708">
        <property type="entry name" value="DUF5648"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18885">
        <property type="entry name" value="DUF5648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5648" evidence="1">
        <location>
            <begin position="21"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="17568" checksum="2F60D0DA602DD409" modified="2023-09-13" version="1">MTASDPPPETRSKTAKAVVFNRSYAKTTHDHFYTTDTSEYHNSFLNLSYVAEGAACKIFSDTGEGLVPLFRLYSSGYSDHFYTMSSGEVTSAIANNRMIFEGIAGYVYPTSKPGAIPLFRLWNGVISDHFYTTSEEERLKAINSLGYNDEGVAAYVLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKD2</accession>
    <name>A0A9P6JKD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKD2"/>
    <dbReference type="OrthoDB" id="3045996at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="65657" checksum="28DBCABD6B0DC506" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKJ6</accession>
    <name>A0A9P6JKJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_861932</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKJ6"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07857">
        <property type="entry name" value="STKc_MPK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="434" mass="48939" checksum="A3B4043D9F3CF373" modified="2023-09-13" version="1">MQRHSFTALNSTFVVDSEYQFVKELGQGAYGCVVAARHRRSGEGCAIKKITNINTKRILTKRCLREIRLLHHFRGHKNITCLYDMDIVFQNGNFDEVYLYEELMEADLHAIIRSGQPLTDAHFQSFIYQTLCGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGYTPGGGTSRAAGNQGFMTEYVATRWYRAPEIMLSFANYSTAIDVWSVGCILAELLGGKPIYKGRDYVDQLNQILHYLGTPSEDTLRRVGSPRAQDYIRSLPIKPRVPFSTLFPQANPLAIDLLSQMLCFDPAKRVSCEQALNHPYLQVWHDPADEPVCDSKFDFSFEEEESIDGMKKLIVAEVNSFRSEVRAQARAAGQIRRQDSLPIPSRDEILSSPVQEYGPHHGATSSFTHGMGHRPPSPIMDDPSEELERELASTHINRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLB4</accession>
    <name>A0A9P6JLB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">CPII coat sec24 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_909448</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLB4"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01479">
        <property type="entry name" value="Sec24-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041742">
        <property type="entry name" value="Sec24-like_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="WW" evidence="13">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9525046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="935" mass="102423" checksum="8E5079145E8CB23B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN01</accession>
    <name>A0A9P6JN01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_884928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN01"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="53491" checksum="C041AFAD88BA27C7" modified="2023-09-13" version="1">MYSRRGSATQTILARKNSGTLPQYGGRLHLKSLPPIHRIPAEILCDIFMKTQEDSVNWVVIPAGTYIPPLTRGTTNPVVLSHVSSRWRAIALNLSALWSTIEVSRATLKEVHRVTTFLHRAKDHPLTASFRTSRPKRGESIDFEVDSLLLKALLSRTSTWCCINFYILHQYLPLLVEMLSRAELPRILRSVHFGAQRNPPHDSAQVQRHLDQIWTFLYNSPSLQHVSWDQECDFVIPMQAPLQQLQLIGMKSDVGIGNLIQALPHCQNLHSLDLFSVDTSPLIDDPPTEILLPKLQSIIIGTRTAVDPVFRILDCPSLSSVVIQSRSMQAPCTIRTLLDFFARSRCFLQLLSFDSEQDDEDILSLILAPEMKHVNSLKLELPYLPDSVLSMLQTLNRDGSQAFMPNLRLLELRACGQADGLWSSLLLSRWFTDLQNPSISTRGSLQSFQLSGSNLLGTIDAAFMEQNGHVIGITCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JND9</accession>
    <name>A0A9P6JND9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_769816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JND9"/>
    <dbReference type="OrthoDB" id="73076at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="26550" checksum="07E046B6F3B803FF" modified="2023-09-13" version="1" fragment="single">GVGMQNFTYTAAWEEFCHLTCVHSPKAYESLREYFPAPSQRNLRKKEARQPPFPMTICSCSFYLAEKHLKALDYTGPVGLSTDDTKLFAMFQLYYNLEKKAHYLIGATDGPILVANPENVREAIEEAQHRKAEKVNNLFALKTANTNKDSLGLVAPIIVAALPISDSMDAPALLDLHIKVLNGLIDRGIQVVSYACNGTEVERAVQRMFLDKTSKCKYRIKDPRDGGKDLVIVYGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNU4</accession>
    <name>A0A9P6JNU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNU4"/>
    <dbReference type="OrthoDB" id="268763at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="764" mass="84287" checksum="A6AC12E78F00D25B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNW8</accession>
    <name>A0A9P6JNW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNW8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="206" mass="24288" checksum="9BD59D849FCEEFA7" modified="2023-09-13" version="1" fragment="single">TRASSTERGSPKLSSVSKPITPARPYLRRTQHQVPTPEEYSKLPLEEKLNQLYTQGFHQMKASMPESSKFYKPSQSGFKEPRKRVRRGEDKNKALEWVRESINILLGIKSTSELLTHNDIFPKDTPLQQHMRNFDAHLHRSPAIKPMKVHWESIHSVWNEVLFEEFKKLSIDEGEMLELDEEQELYDMFFARLKRMRADLWAKRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP51</accession>
    <name>A0A9P6JP51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_854930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP51"/>
    <dbReference type="OrthoDB" id="2014333at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="10454" checksum="A4B639213F3C4D2A" modified="2023-09-13" version="1">MARAHRVAATVTIVTIAYILTFFGVFSVPLVDEKVAAQILPVLPWWLLVSFGAYSLVSIGWGLLTLRECPEAYNELMSEIAEAKNDLRSKGVTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPI7</accession>
    <name>A0A9P6JPI7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_854359</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPI7"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="9">
        <location>
            <begin position="386"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="566" mass="64318" checksum="1495D65641727276" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPX6</accession>
    <name>A0A9P6JPX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_836171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPX6"/>
    <dbReference type="OrthoDB" id="20729at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051767">
        <property type="entry name" value="Nucleoporin_NUP42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527">
        <property type="entry name" value="NUCLEOPORIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="3">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="325"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="440"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="504"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="726" mass="72460" checksum="2EE704DA68CFA420" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ25</accession>
    <name>A0A9P6JQ25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_894538</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ25"/>
    <dbReference type="OrthoDB" id="3066029at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="38471" checksum="3B03F886C9E75836" modified="2023-09-13" version="1">MIGSSYSTFYGGRPIYLLGIPLLVYASFGVAAYRTVYQLLFWRFFQSMGASPGLTIGSAVIGDIYKLEERGAAMGIFFGATLLEPTLAPIAGGAVAHYSSWRTMQSAVGVCGFGVLIFMYYAFPETYHPCQRGVDKMEPGTHPKWRPVILNPLRPLWMPRSPNLLFVSLAAFTGILSDYVLQIPIAYTIGAKYGITNEALIGACFIPAGLGNVLGSIYLGRLSDKKNIQWRAKRNGTWCAEDRLRATIPGALFYIPLSTVLSGIFVTYVAGPVGLTLNLLCLFLNGFGVDGVLGPSAAYFVDSMHSRSAEAMAAYTGFRQVLTALSVSLIIPMVEKYGVLVTDTSSALLAWVGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ29</accession>
    <name>A0A9P6JQ29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_836106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ29"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="45891" checksum="DC132675641D827D" modified="2023-09-13" version="1">MALRPILLHYVNQACKQDGGLSCDACISLARIDTDISATRAKLDEQLAARHSLLTQLNTKHDPMGNRLPVEITSKIFQHCLPDLPSPETFENSSRESNTDHEFSQTTAKLTSINRHWRSIAHSTPELWTSIFLNFTRWSISGDRLPIILTNVKQRIQRSSNLLLSIRLIAGEGHALVSSSAQMLEAFCLEAHRWRSLCISAPRKVISVILTQTFPKGPTNSTIVSFLDFLPRLMTLECQICNGDQTFNSNPPLLHPSLKTLKLTAIEAVPNLLAKITLPALEIAPSEIQSTHNCSNKTSLVPSSFLSDLAREYCAGDELGGGFGFKIDVTNISPYPPRSSLHRLPRSPAVAFFELFLLPNMTNLSERKTYFYSSGTLKLLTTPPTQCPSDLHINMNGGLAEFVMVWRRILCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ41</accession>
    <name>A0A9P6JQ41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_883678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ41"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="188" mass="20287" checksum="AD8CF5CF315A6C02" modified="2023-09-13" version="1">MLETALILVVGLTGSGRTTFINEASGSDLKVGGTLKPCTAKVTAAKPFELSDRRVILIDTPGLSSDTLTKISTDVKKLCVSQKQNLAGIIYLHRILAKHIDPTSTLNAQMLKLELNQTPIVIATTFWSKPGQKLSPTPDDIFGEGSNVNASVEKYEDSQESAHKIVSGIMRRSPPAETEIHGSSWCCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQI0</accession>
    <name>A0A9P6JQI0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQI0"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="134"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="419" mass="46588" checksum="04D53CBF9AF90B50" modified="2023-09-13" version="1">MVITRPHRSAIRLGSIKPTNAVPNLVPRRQLSGPSKQPSISGGILETFRRWHTAFRRRLCPSTQKDNSTESPQDQESFHPRVHQLSDLARVAKPLELPSDVHIKFLDTHHAVETAIAPILAPLAAEEGGVSQILVSMDTERNIMRTIGVSVIQLAFHSIPRKIFVIPVHKFEMLPVSLMEMLTSSRVIKIGNQVNNDLSTLQRQFKELQQTKTFATVDLQAFCLQHGVIRPGDSAALQALLVKALGRYMDKKPHDYHNWEGRTIPKLMLNGAALDAYAIRLIYEKAAAQPLVPLVEFNTQPGTAVSLLGRIGWFNEIVARGVITSPQPNKYDSIEVNTPDRNRLLVDITELVHPDQGAQFYPLPGVHDRHSARRMKPISYTLGQLRSRTGDAPLKVVWPISSLEMSKDTGTLAAAGEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR38</accession>
    <name>A0A9P6JR38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR38"/>
    <dbReference type="OrthoDB" id="3234283at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="479" mass="53489" checksum="BB80110DFCFB616B" modified="2023-09-13" version="1">MPKTRNVTRSEWAAASGSNAAASHSTATRRGRNENTKDREKENTGRVTTRTRTHRRETGLPSTTTTLGASILPMKKAIGGKPLGKGKAKASPLKEKKIPLQDITAQFLPAPEFANRGEASEHESQGVITRHVASVTPVRDARTPIHLQQPLSPLPPSSPPSDFQVSPIKQPEFSIARTIDDLDYSPERNHPIITFDPWPEFDDAVMREQQLSTPSISNSDPFGFGAVERRLKVERETELAPSENVRVEGYQSADEDLVNIPVADTSSPRQVKRLKRSRAFDANEDAANGPLSEDEAPVFTAPAHFVTPPTPHKDKLKRRRLSHEGHDVFSPCESSIESSPSPTKTTRQSDAHVTHDPLEEFNEELDKHDSSDFLADKLVKSSRKPRVSFKEGVPPDAVARNLRPRRRSQPTSSPIKRSRSTTAKPKTKKKSPIKRKTKQKVEAEGGEKDIKAIRERQARIDYFKRLDDYEVEKEDVFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRE4</accession>
    <name>A0A9P6JRE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_762497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRE4"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="398"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="684" mass="78006" checksum="A3856349D0AA9219" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRR3</accession>
    <name>A0A9P6JRR3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRR3"/>
    <dbReference type="OrthoDB" id="3048642at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="746" mass="82025" checksum="7E31D56D4C1348EB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRS2</accession>
    <name>A0A9P6JRS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRS2"/>
    <dbReference type="OrthoDB" id="14527at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379">
        <property type="entry name" value="UNCHARACTERIZED DUF1308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379:SF0">
        <property type="entry name" value="UPF0415 PROTEIN C7ORF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="698" mass="77793" checksum="E9138FF90DC9F74B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSD5</accession>
    <name>A0A9P6JSD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PUA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_850396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSD5"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="3">
        <location>
            <begin position="28"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22130" checksum="46F2B77316A59E9E" modified="2023-09-13" version="1">MRIEDRRKVLLQDPQKFPPDMRGESKYGPVHGVELFKVFATKQEASDARIHRAPRAGIAGSSLVKGAQSIALSGRYEDDIDNGDIIFYTGTGGQEVLSARDKARGRIPRQEVPQTFANQLNAALRVNKELGTPVRVLRGANKHSPYAPSEGYRYDGCYLVQTAEIAVGRSGFNICRYKLTVRRVFFRVYPSSLTLTAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSD6</accession>
    <name>A0A9P6JSD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSD6"/>
    <dbReference type="OrthoDB" id="2788977at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="212" mass="24520" checksum="B88A478144A84994" modified="2023-09-13" version="1">MSYTKQYTYQEPGPSKQPGPLSSEHAGTISTSKVELALKRCCKTSLEYEYLVKGLESSLSDHLSNFRAVESLMQESYKNVHRNVQRADRVSKVQANHIKQQLGDLDDSLTELADTLPTIQTQVLDIKQAYDSGWDKAQELVTDLTWLNTDFYERWRMIIFSSSSPVSWRWKVYMRTVFVVSFVVCSWLLWIGLTGAYRAHRHRLVWGEKLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSL5</accession>
    <name>A0A9P6JSL5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eisosome component PIL1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_786831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSL5"/>
    <dbReference type="OrthoDB" id="5599269at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036286">
        <property type="term" value="C:eisosome filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028245">
        <property type="entry name" value="PIL1/LSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962:SF6">
        <property type="entry name" value="EISOSOME COMPONENT PIL1-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13805">
        <property type="entry name" value="Pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="941" mass="101498" checksum="A2C0C7A532491A42" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTV7</accession>
    <name>A0A9P6JTV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TatD DNase family Scn1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_808076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTV7"/>
    <dbReference type="OrthoDB" id="413993at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="372" mass="41831" checksum="1B4DF2607E50DC32" modified="2023-09-13" version="1">MTDTSPLALPSSDILAHITDVHCHPTDAPGGVSTSSMQQLGIHICAMSSGPHDQEKVKALATAYPEKATPAFGYHPWFCHLISTERSLGLERSQGMSEKERHYRYLFLPSTETLSEEKSQKLEAQFIELLEHLPDPTPISATLSTLQSNLESFPNAMLGEVGLDRIFRVPLDYFSSPRTLTPFQIPLEHQLDVLEAQLELAIELGRNVSMHSVKSQQATVGLLDKIQKKHGKEKWNKISVDMHSCGLSSETWRDLEKRHANVFISLSTVINTKQANLRDLISRCSPDRLLVESDYNNIDMVTPQTWDMVQLVSEVRGWPVETEWKDEGDISPGDFGVIRRLERNWKTFRDGNHPVKGKSSKVIDFGSEDSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU59</accession>
    <name>A0A9P6JU59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_847384</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU59"/>
    <dbReference type="OrthoDB" id="2924818at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="5">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="5">
        <location>
            <begin position="178"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="178"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="338" mass="38478" checksum="A6B33D10950C7161" modified="2023-09-13" version="1">MAEKGVYFAYDSNMWFDQMHRRCSDAKVLGVGKLHGWKWIVSNSGYANIIPSPHDVVHGVLYELEAHDEAGLDYWEGQKSTKTEVQVDVMKYKDSLSQDLVTIFTYVDANNVQEGTSKEEHTGRMSKAIADAIREGIPAGYFDIHIRKFIPENWKQQQTLGTSKDQPGPATLGNNTVYFGYGSNIWLDQMKRRCPNNKFMGVGKLDKWKWIINTRGYANIIPAVPDLVYGFVFELTPEDEKELDTYEGSGYQKEYHSIDLVEAKDTYSAGTRTALIYIDTERLKEGISKKEYVYRINMAIKDGLEQGIPKDYIDRYLRPFIPPLPGDNSSTTPVLAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUV5</accession>
    <name>A0A9P6JUV5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_783790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUV5"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="51"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="307" mass="33798" checksum="C186F2D8916B63A7" modified="2023-09-13" version="1">MNDGQEAFRRFTNQLRTVGGSGGRIPGGPGGLFAGSGLLIALVAGGFALNSSLFNVDGGHRAIKYSRLHGLRDEIYSEGTHLMLPWFESPIIFDVRAKPRNIASLTGTKDLQMVNITCRVLSKPNQTSLPTIYRELGKDYDERVLPSIVNEVLKSVVAQFNASQLITQREHVSRLVRENLTERARKFNLILDDVSITHVAFSTDFTHAVEAKQVAQQTALRAAYLVDQAVQEKQSIIIRAEGESKSAELVGDALKKNQGFLELRRLEAARDIATTLSQSQNKVMLDSQSLLLNVAGNDAKDLLNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUY0</accession>
    <name>A0A9P6JUY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">U3 small nucleolar ribonucleoprotein protein IMP4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_842986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUY0"/>
    <dbReference type="OrthoDB" id="10253204at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000001">
        <property type="entry name" value="IMP4, U3 small nucleolar ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF2">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="3">
        <location>
            <begin position="82"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00040513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="303" mass="35170" checksum="54E8E1CC28743AC9" modified="2023-09-13" version="1">MLRRQARERREYVYAKSLEAQERQTWERKQQLKDSLATGKTLPTELKKGAKDLGKDLAYDEAQPEPTTHIDNEYSRAGVQDPKIIITTSRDPSSKLLQFSKEIRLVFPNSHRINRGNYVVKELAEACRANEISDLIVVHEHRGVPDALIVSHFPHGPTVYFTLNNVQLRHDIAGYNKSTVSEQYPHLIFENFSSQLGERVRDVLKYLFPVPKEDSKRVMTFANEDDFISFRHHVFVKTGREVQLAEVGPRFEMKPYEIRQGTIEQTEAEREWVLTHYTRTAKKRSALSHSRFSEPPPAKKLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVI1</accession>
    <name>A0A9P6JVI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_841788</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVI1"/>
    <dbReference type="OrthoDB" id="1630758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="TRAF-type" evidence="8">
        <location>
            <begin position="79"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="79"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="126"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="230"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57345" checksum="FF90243DBCA0CCB5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVL6</accession>
    <name>A0A9P6JVL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_480756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVL6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="253" mass="28948" checksum="2BD8B87750A28513" modified="2023-09-13" version="1">MAPMQIANVGRSYLGLRPTPSFKGERGVKSIRSLLSLHPPDMQQTSPNSGHRTRRTCTQKCTQCLPFQSCRLFPRRWDNKIVLPPPSEIREPNKFFVPHHLRGRPDWDLTPEARNEMREWYQDRRKAFPVKFPAWFRYSDDSSPPSRSYNTENCMSIPADDYADRAPIRSISIIEVHPNIIHPPTVPDIHAQMHQTIIHRESMASNLGYHHGGLPASMITGGIHSVYPQTWPTAPRHPSRETPMQVMGSLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWA3</accession>
    <name>A0A9P6JWA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_780777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWA3"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="54"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="24224" checksum="48C028355C6D2626" modified="2023-09-13" version="1">MAPKNILFVLTSADKTFTGLPTGWYLPEAAHPYYSIIPHAHIDFATPKGANPPVDQISVQNFTDEESVKFLKDETVIQKLATAKKLTEVNSKDYDAVFYVGGVGPVVDLAIDPVNAKLASDFWNEGKIVAAVCHGPAALIGAKDTSGKSVFAGRKFTGFSNAEEEKLGFTKDVPFLLEDKIQELGGIFEKAPGLFEPEVVIDGKLFTGQNPASAKPLGQEVAKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWK2</accession>
    <name>A0A9P6JWK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_233828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWK2"/>
    <dbReference type="OrthoDB" id="2879353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="12508" checksum="BCF270AA3E2AE18A" modified="2023-09-13" version="1">MPTSDGYIKTTSSGSKFMAVFTINDTNYTFSGPLGGSSQPWNCNNASVTYKSRQKDLTSSRTFEGHVGPRKVRFQLENDVTITGTLDMPIHPPNSVSGTGSWTSNFEIKNAYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWL0</accession>
    <name>A0A9P6JWL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_889107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWL0"/>
    <dbReference type="OrthoDB" id="3234968at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="191"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="49010" checksum="AB1D5E4D3084BE4B" modified="2023-09-13" version="1">MVAHLPPDSHEASIHKSPIAFRRRYSVPSPIPFLSVICILYTSLSLINPAVFSVDAANVTVDDGDGRIAYAPAGAWAKSAQTSLNYGDSHMLTQNPTATATFIFKGTAIYFLSPLWPYKVNTAVALDDAPPVLIDLVDHSRPDAGQGPETVGSEVVWSVSGLENTQHTLHISVGAGQTFAIVDGLVYTDPSLSPSSQSPQSGSGSNPTTTGRILASSTSGSSNAASTSGSSDKHSPIPIALGTLFGVLGILIIIGAVWYFCRKRRRPISEAWTEGSYGGPGGANSHPGYAYGGPAGSYGHQLPPQAHGVNGQYDYSQFGYGLNGAPPPSFYAPSYHGQPSQGPSSYQGVGPNRAPNRYQPGYTLSTITEKSTPQMADGNRTMPGTPRSGVGALGTTGVGAHSPASQQSDLGYYTAPGSSAGQYSPAQPGSAGQHSPAQAAQVYSAGPVQQQQQSVGKQSSRTSEKRRGQSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX02</accession>
    <name>A0A9P6JX02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX02"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="11674" checksum="2ABF191341E91897" modified="2023-09-13" version="1">MLIQHHCIITASVHPHYLHHEHAVTHHVSTLDCIVSILFAQCIYLRHLRPFLLRGIDALFLPSIYIILFDFTQLHFLLVSKYIECFYPQRGYYYADSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2I1</accession>
    <name>A0A9P6E2I1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158153">
        <property type="protein sequence ID" value="KAF9521289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2I1"/>
    <dbReference type="OrthoDB" id="3063226at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="32484" checksum="165995DD4E9F8AD7" modified="2023-09-13" version="1">MFDQSSFNKTDVLPVECMKGSLNFSKTNGRVYLLPDGQLFYSPNTCKPVSVPPPPVPGQNIFTPPSYRGRPNYWGLNIHNFLQPQWWTHQFGWVSFLDSSLLEADKALLYQQDWLKLEYQLRNVHILLHKHYFYPTVSPHEPSKLGYLSSHINLRILQIALKKSREWFSLWMALALFSIACAEAQEEYYRPYPHLARAKWTDWLVAEGASYNIDHCWVDKLAASSVASFRSNSRAGVFVNLKGGEWFQPAPSWFCKHHIPVCLRPFASPTAKHSIVSNEIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3C9</accession>
    <name>A0A9P6E3C9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157994">
        <property type="protein sequence ID" value="KAF9521743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3C9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040360343" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14165" checksum="900C6A77D08A68B2" modified="2023-09-13" version="1">MIQRSPWLRVMVLLSLEILHLHTSTPDSALEETRRAPGICMVRSYHLALGEVDYRCFTILLVIRRRSTFVAYSIELSASFFPISFRFHYVSLIMNPCIQPLFSTHFNCKGTSKGPAEGRCVAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E406</accession>
    <name>A0A9P6E406_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD/NAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_840695</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E406"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF26">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="646" mass="71544" checksum="8FAF7A79950CD086" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E458</accession>
    <name>A0A9P6E458_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E458"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="81"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="634" mass="71573" checksum="519A696CDFBD09D5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4L2</accession>
    <name>A0A9P6E4L2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_911347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157947">
        <property type="protein sequence ID" value="KAF9522390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4L2"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="214"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="470" mass="53629" checksum="7ADF5D265DD5081E" modified="2023-09-13" version="1">MMFPTPKASKRQLSTRILQEATPITLNNHNLPFLVFGYSISRRSFRTFSTFSGQGNPGAIWIRRNGICIWFFVFWATRIREVVAVSNMVMSSCWPVVQMVRLLFKCTSKTEDPNAARNVSMIHHHNTEVFNSLPLPAASPGLSALEEALQIERATSVDGGSRCSWKRVEQLYLAKTDPIQFLLEHTAPDALVDSGDRRDPPQCAPQTRDGIFHEIKKWANSREGAALIFWLFGSAEAGKSAICQSIAEMFNHRGLLLGIFFFSRSTASTGRSNEAIPETRPYIKKVIRRTPTMFTKTRASQMAELYVESLKKLKIRGFFQRHNVDLWKKVRLVVIDGLDECQDQDVQCDLLRQVIQFLIDKSSPQFILASTVVRYISDPTSDDHPDKRLHDIIKYSTSSSSNKPFDSLDILYRFIFAGVNPKYRDKVWCILGLIHLASRKEYKFHQSLRISLTQSTVMTCQEPFIRYSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4X4</accession>
    <name>A0A9P6E4X4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal L1 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_871953</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the universal ribosomal protein uL1 family. Highly divergent.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4X4"/>
    <dbReference type="OrthoDB" id="10251727at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000004">
        <property type="entry name" value="Ribosomal L1 domain-containing 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="259"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="359"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="471" mass="51885" checksum="1EC8D508DBABE114" modified="2023-09-13" version="1">MPKNELIAEHVSLKQIKKAVDALHTHESKKKEKFEENQILPAKEQFVWLNVTVKTIDAGRTLKPRKIPIAHPLVDPRTTPVCLITKDPQREYKDLLESHNIKFISRVVGIEKLKGKFKPFEARRMLLKENGMFLADERITPLLPKLLGSKWFEAKKQPIPVCLTRKDLKGELERAISSTYMNQNQGTYTSIKIGKLSQSPAQIVDNIKTALPVIVSFMKGGWVNIQSFNIKTNSSVSLPIWACTLDDSENGRWLGLPAKEEEESAEEVEEDEAAQPLKYTGSKQKRQSNSDAEEEKAEKPRKKARTVGLSQISKNAVHGDSTPISGGKKTGQASSTTKPTEVKSTKSVATSSQDRKMKTSTSTTTPTASASPASKPLSQKKALPPQKSNTTASVKTKVTSKNSEISPRPTKTSKSNDVVSTKDRSLASALSTLDLKQKRASGMLEKKKQLVAKAKGGKSVKNVVLGKRVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E517</accession>
    <name>A0A9P6E517_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_864211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E517"/>
    <dbReference type="OrthoDB" id="3210866at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="478" mass="53754" checksum="3F0B99B02AA85A79" modified="2023-09-13" version="1">MHSTATNCSMPPPEHDLMDVDPPAAVAASVQEIALSTATQDSGALPFPARDPKDSCLTVCYLQVIGASNKQLKEWCRSYGLSVSGKKSDLVARLKEFSSDEEKWKRFEPTKRRMHCNPHTDGQTKSSSVKKLTRRSDAIFPERDVQPSAHLPHLLPEGPAPWVLAKEKALLQWAEETSAELPYVSKENREKAAEIYLQKSRAAMNGGVEYPPQVLKQTNDRLDQLSALIIQQNTNARVNINPALSTSSISSCMSWEISPPTLQTVTNNEAIAPTRTIHLDGWQLIFTEADVGRPPAHSFAADPPFTLEVQLRKLNAMWDSDPAHWRGLDTGLKICGADIPLAYLRDVYATRRGAKSQTGHVWKQGQWKGIKNSWFNWRDIVSYWRQGSEAQFWYIFSTPSGERLAYSKILDKITELRNTQDITTAGKARAEYISDFDVTFGYRKGSEKKVMTQDRAIARRYRSLCNQPAQGDDDDDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E519</accession>
    <name>A0A9P6E519_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E519"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="9735" checksum="C4D04D829C97AE62" modified="2023-09-13" version="1">MTLPGRRPFVTSQKDFPVVIISERFLGPPKKSLKVPWVVSQKPEGTTKMVILGDLSAQKTSFWVKSEMTSKMAPTRKSFWELPQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5R2</accession>
    <name>A0A9P6E5R2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959:SF119">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1299" mass="144093" checksum="41C351ADBD62F0DD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E650</accession>
    <name>A0A9P6E650_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_899016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 13">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3151137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF145">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="5"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="989"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="1178"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="898"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1547" mass="175473" checksum="F0A9C52CE37D5294" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Q3</accession>
    <name>A0A9P6E6Q3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Q3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6733" checksum="F302A52294888CDF" modified="2023-09-13" version="1">MSWFLTAHSSFGNQFIVRLYLFIYFSFLTQQTWHIGRGIPVIVDSKCFPSSLLIFSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E789</accession>
    <name>A0A9P6E789_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_798733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E789"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="373" mass="42499" checksum="3264A825A4A9157A" modified="2023-09-13" version="1" fragment="single">MGSLNFLFSLFGWTFIPDLATRNLLKFLYQRSPIRVAQPQPGSFQQRKHYIIVYSLVICGYMIWTIIQSSNNMPPNFYEILGVRPDVDETGLKLAFRAFAKKYHPDRVGPKGEQLFMYVRDAYEALKDPAVRFAYDRFGPDAAGWRKQCKTTREFLRQGLMVSSGYHIFSGIALLFWSAIGKPSSVSFWRYILYFSLLAVELSFILSPFPATPGSFLPPSDPTSMLLPTSSAILQRLWPNRVPYQHILFLHQVFMFFTVALTRVVPQFTTLLGNDDAGARELEPLERAIWERIYGAVAIADREASVILHSIVHSPYHDPTFAAMYPATPQRTMKALEDLTPEMEAMVIEANIKNQREGPIGKAWRAVLSRNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7A8</accession>
    <name>A0A9P6E7A8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_898542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7A8"/>
    <dbReference type="OrthoDB" id="3257338at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="213"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1094" mass="123606" checksum="32DC5B0F023CB584" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7F2</accession>
    <name>A0A9P6E7F2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavoprotein NADH-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_652466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7F2"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="387" mass="42597" checksum="14C4F30041910645" modified="2023-09-13" version="1">MTTTSGSSNYPDLFTPIQVGTHTIQNRIGMSALTRNRADGTYPTDLMKEYYLQRVQGGTGLIVTEGILVSRQGTEWQNAPGIWNQQRVVGWKNITDAVHLAEGKILAQLWHPGRTSHPDAPQQKLAGVPVYAPSAIAARGGIFRFLPGEPGYVAPTELDETTIWKIIGQFKQAAINAKAAGFDGVELQGANGLLVAQFLDNTSNTRSDKWGGSVENRARFGLEVLKSFKEVFGENVGMKISPCGGYNDVGMPLSDTLETFSYFLREADRLGLAYITLVRYHPNFDMVFDGVNRSTNFDVLDSLRSSITNSKVFLNAGVTPEEGQQLISEGKIDGIMVGFNMITHPDYVKRVKTGRPLNNAPNFPLLQRNVSDEDWHSGYTDYPLAKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7W1</accession>
    <name>A0A9P6E7W1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7W1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="17799" checksum="7439B1EF737565FD" modified="2023-09-13" version="1">MQPRTVALEVVDSERYGMHDDNDWASVTPLGHGFVKVGDGEDDFYAISMYHQIHCLNGFRKVLNGHRNDSRAEHDAMHNLHCLSYMRQVVLCNADLALEPAFLAKNTDGRLTQAAYGVGVTHQCRDWEQVRSFAEENFQLWKGGTTGFAASEISAQLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E897</accession>
    <name>A0A9P6E897_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E897"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040151222" evidence="1">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="62" mass="6995" checksum="8A2E80359C053C54" modified="2023-09-13" version="1">MPSFRKPFLLLYLTTAAAAVFEFPPIWFLQTQQLDSSMTLINMSHCTAGNIYTKHGDLITMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8K4</accession>
    <name>A0A9P6E8K4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8K4"/>
    <dbReference type="OrthoDB" id="3268838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="626" mass="72019" checksum="A972B26BFC92D404" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8T0</accession>
    <name>A0A9P6E8T0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General amino acid permease AGP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_603122</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8T0"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF15">
        <property type="entry name" value="GENERAL AMINO ACID PERMEASE AGP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="57"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="556" mass="61502" checksum="432440A60B48E4F9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E900</accession>
    <name>A0A9P6E900_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E900"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8531" checksum="9E9BC2D3DB180BE3" modified="2023-09-13" version="1">MEKNTRVMFKAAEGIITLIEIRISKRRQKNQAKKAIESGIMKSNKIKSESAKRRENAHIIFNLQEKEGYVLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9I1</accession>
    <name>A0A9P6E9I1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_838343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9I1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040179932" evidence="1">
        <location>
            <begin position="18"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="26"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="174" mass="18790" checksum="B6D91A1AE59D11B8" modified="2023-09-13" version="1">MLARLSIALALAATGLAQVVVPAGYRTATISTAWNDKFVLQPQAPIKSGSAVVLYSVNNHIEQQWYLKDGSTKVQLANTTLCLDAGSNHNNGNPLTVTTCSDTLASQKWQYNTDSQIVLDQTGTKLCADLYMGTLQNNTRIVIWNCIAGDKNHIWKTTNVTVPVVPPVTTPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA54</accession>
    <name>A0A9P6EA54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_553699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA54"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="100"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="40966" checksum="959A1953B6CA192A" modified="2023-09-13" version="1">MLNPSNTMAPPSMANNTIQLFTGAHNVCIEGSPVFNISNNAEADFFTRLYQVITQNALHNANRKESVVRCLPGTGRGLSRGWKEVSTTPVEHNSCGQGVPAGFGKTAIAQSISEQLVRDDRLGGDFFFSLLGGRTDPRKLFLTLAYRLAKSNPTLKSAIESAIKRDPEIVNASLEDQFQHLIVSPLKSLKVNDGTLPLVILIDGLDECHNEDNQTKLLNLVTSIPQSQALPLCFLIVSRPEPWIAHAFKSTHSVTTIHLEEDEAADEGIRLYYNTEFAKLRAGPKYCHLDSNQWLRYPQLLIHIAASSFISTHPCTTVATVVSWSDIVTVSLLLGLCAAGLEMHQRQTWSFSKSLAEYNTIVHLRYLVALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB33</accession>
    <name>A0A9P6EB33_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB33"/>
    <dbReference type="OrthoDB" id="58416at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="28"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="242" mass="27708" checksum="E81CEC1BFB306033" modified="2023-09-13" version="1">MPAPFPLLDMPSGDRNNVFDFVAIHMAAAHNLFIQGVNAMVAHAPHVEGDKVQPFVIFAISSLEGIHRHHHHEETYYFEALETKLGKGYLDSTKEQHDTFVPQIDELEVWLRGVRDGTHVYDAKKMLSYIDAFADKMFEHLNEEVEKLDRETIRKHFTEQELKAIDAEFMKRATSGVDLYTALPLATICANPATPWFPAIPTPLKWANRIWFSRRYQESWEFGPLDLYGQPKALLSPVTQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBM9</accession>
    <name>A0A9P6EBM9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_508988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBM9"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="36697" checksum="3DC77D6E75838069" modified="2023-09-13" version="1">MFLLPQELMNEVIYILRNDKSTLNSLSLVNRTIARECQRYLFSRIVVRGPNKPLHDFGGSAAALKQLLQSSPHLARHVRCLELFDTMRYRRRASTSRGDDSTVKRWLPKDRYIAGCISNFTNLEAFIVQFHMNDFPLGSTEVPQGLVRCCQNVLRRLQHVSFMCISDVPDLSFLEEGLNLKHLWICEGFYEPAQTSQTSVNPPIYLQSLCLEQKSSYGIPYHYFLDPSCRFSIVMLRKLAINVASSSRAGRHYVQIAKLLDLCASTLEELEFVPSVFTLASVTNGETSAINLETFHGCPYYSNHLPLSIRISRNWCYPSLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBR1</accession>
    <name>A0A9P6EBR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBR1"/>
    <dbReference type="OrthoDB" id="3247499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="438" mass="48480" checksum="826925C0BFE49611" modified="2023-09-13" version="1">MTRRMALQLPNETLEVIFGDLPPATLAILSRVSDRFNGVAERLLYTSPVITDVITPTSPSPVKTLWWCNAMQRRGREYLLQTTVKKLCIRWQTNPGHQQGGSGSEPQACPLYLLNACEWLGEVLPRLVGLESLEIWLGPANLLPAHELERLLQHPQYHLQQRGPSTGVPIIKPMHAIERVLWNCRFPYLRSCSLGAEWKRGVQPYTPVLTNFLSTLASLRHLRVADLVDRSSLDSLSPNQLPPCNTLTQLNSFRGPAGAAASLIPGRPVQYLALTGHDSDLHEFNLERMTRGSVPLKSLDLSAMSIRTMLLQNISLNFGCVETLRVRLALRHTLHFAESGIRILTGLSRVLSAFSQLSHLDLSPTGLDAYGVGRTDLSEELGVCKEWSRACPTLRKVTFPSLIEWVLIEEAGGMEGSGAVWKCAEVAASTRGGSPTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECW9</accession>
    <name>A0A9P6ECW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_837172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECW9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="38626" checksum="169245AAD9C91006" modified="2023-09-13" version="1">MPNVRHQCIGDSRNTDPFCRSALSLKRQGILRELSIAPYKDGISGVEDIDQDEISWRPLEHIEKRCRVKGDIENAGLPVSWDALEYLERQWVQTLATWIWLCTFCKSLLGKRRIHLPFFYHFRVQQLKYDRQNLNGKVVNRRHLRQLALVPVLSTSNTVQLFKFIATCTIHTVISYTPGPHALCFSVPVGQPIQAANPCPFNFRFGIEPNPDPEPFEDEAAGVSTGAGVNVGVPDPPNPPAPPNPEPLPPLSPPPPEPARRLIIFEVVENDEPKAGGADRGVDIDTDVDAPKWDKEAREVVEGSFDDEDKDECIPIHWCERVRGVHEIVNVKAMVHAYVNGPMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED41</accession>
    <name>A0A9P6ED41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxidase</fullName>
            <ecNumber evidence="13">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_445456</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="13"/>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED41"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 13 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="14">
        <location>
            <begin position="91"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9526911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="382" mass="42309" checksum="A230A9D2C4DB36C3" modified="2023-09-13" version="1">MSLNVLRASIRTGGANPLRRASQLHRSAFRSNFNRNFSTPPPPAPEAAKSATGLYLGFGAVAAGGLAYYLLATDGGKATASTAKSGVQAVKVKANFVPTKEDYIKVYNRIADILDVDDYDDGSYGPVLVRLAWHASGTYDKDSKTGGSNYATMRFHPESQHGANAGLNVARDVMEKVKQEFPWISYGDLWTLGGVAAIQEMAGPHIPWRPGRIDGFAAQATPDGRLPDATQGADHLRHIFYRMGFNDQEIVALSGAHALGRCHSSRSGFEGPWTFAPTTLTNDFFKLLFEETWVWKKWSGPKQLEDKKTRSLMMLPTDYVLVQDKSFKKWAKAYADSQDLFFKDFSDVLSRLFELGVPTEQFVSPEPWTMPKVEEQQPVKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED70</accession>
    <name>A0A9P6ED70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial distribution/morphology family 35/apoptosis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_895780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED70"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990050">
        <property type="term" value="F:phosphatidic acid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403:SF1">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="11018" checksum="3A5ACC98F3ABD048" modified="2023-09-13" version="1">MSQSLSPECTPLKKVYDSCFNSWFEGYLEPAIAASTKPEQRTEYAKRKAEEFQANCGKVWEQYKACVQGAVKEKGLDQLLEQAREENPLMEPTPPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED90</accession>
    <name>A0A9P6ED90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_884650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED90"/>
    <dbReference type="OrthoDB" id="3190308at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25558" checksum="4168945224262187" modified="2023-09-13" version="1">MYFFQASKRLMTRRSLIASEILKTVMNLFSGVEYAGNPTKIVAHPMPAECRVVREHPAYIKPRGFLQSDYVLIPACAALRRVQKSIIKPPISVDSPPKGLITLILTVTERAFGAYLNGSYTELADFKHDNYWNQLKGHMDNINDKLCHSPPMTSSLMSYDVTMPYIPVDSLSDVVYRLVVDQYDPPPDYQLGFWATLPLTAFRKLSTSLRHQTRAGKSRCPLSLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEE2</accession>
    <name>A0A9P6EEE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEE2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="92" mass="10467" checksum="9949224C9E1CDA42" modified="2023-09-13" version="1">MVFCLYVNNISSFPTIAGLFSPSSWMLSVKRLLRRYGSMRSHMQIVQHVFDGTRSKTCHPSQQPLAELAAVLKLLLNQATTVWDHVLMHAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEL0</accession>
    <name>A0A9P6EEL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_876081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEL0"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="460" mass="49225" checksum="553FDEA1479C3C95" modified="2023-09-13" version="1">MFAFGTNTMIAGNLLRRFRSFVAKPDAIDSSLLAFFVCRVLQVSSQLAGTLSTETHPKLNWQQCTISGGCKTVSGSIVLDAEWRWIHQVGSYTNCFIGNIWNTTICYSNKQCSKNCQLEGADYSSYGISTSDIYLLANETNYQPFRPLNQEFSVDVDVSALSCDSNGAISFLQMDLDGGKGRFGNNQAGAQFGTGYCSSKCPRDLKFISGEANAEGWTPSNIDPLSGSGNYGSCCGEMDVWESNSFANAFAAHSCDVGSQNRCTDAACGTAAAPYSGVCDPDGCDFNAYRLGNQSFYGPSKTLDSNKKIMVVTQFVTDSNTADGMLTEIRRKYIQSGKVLANPTVQVSGSFNSIKSQYCGNEKSLFGDVDAFGKHGGLNQVGKGLGTGMVLSFSLLNDAATRFLWLDSRYPVDKDPSIPGVARGRCGPEPPATLLVDPGAQCVAVYSNIKFGDIGTSGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF19</accession>
    <name>A0A9P6EF19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF19"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040492765" evidence="2">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="132" mass="13973" checksum="BFCFAF56BCE17ED3" modified="2023-09-13" version="1">MYISKVLSLVALASGALALPLRLEARLKDRELVSRELQQQILYREVESIVDSILAARTPADEKPALPVIHVTESPKFPRTNTNSAGKGGGGGGGGGEKSLKLPESSIQGQSNQGKSSTKDMMPDLSALNFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFA2</accession>
    <name>A0A9P6EFA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_725251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFA2"/>
    <dbReference type="OrthoDB" id="2686356at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="119" mass="13011" checksum="488108EE8C44A900" modified="2023-09-13" version="1" fragment="single">PEVVPGEGLPSLKSLGLTSKDLYNMKPEFFNSSIETRSKHFDNSCNPYSTGNFDDAIACYNYLVRIGHWSCLVTPTGRSKFCVSGDAAIQGYNFRSDGNSVSSPCSYVALAAQWVLTHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG15</accession>
    <name>A0A9P6EG15_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enolase C-terminal domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_894456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG15"/>
    <dbReference type="OrthoDB" id="2579025at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010624">
        <property type="entry name" value="PRK14017.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080:SF2">
        <property type="entry name" value="D-GALACTONATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="D-GALACTONATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="3">
        <location>
            <begin position="128"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="388" mass="43278" checksum="B1C6EE7DB5B45114" modified="2023-09-13" version="1">MAPSFISSIEAFRVPPRWLFVRVKTSDGIVGWGEATLEGHSEAVEGAIADFQRRFIGVDADHIQDIWQTAYRGRFYRGGPVLMSALSGLDIALWDIKGIKLGVPVYHLLGGKVRDKIRVYGWIGGDDFQNLYEQAKRRKDQGFTAVKMNATDSSSWIDSPIIVNHAVGRLRAVKSLGLDVGIDFHGRLHKGMAKQLAKALEPERPMFIEEPLLPGFPDEIADLSTIVGTPIALGERLFNRSEFRPYLEKRAIDIAQPDVSHCGGISELHRIASLTETYDVGLAPHCPLGPIALAACMQVAAASPNFFIQEMSWEMHYNKPGVADLHTYLVDPRVFAVKDGHVEVPHRPGLGIAINEELVRQKSKEHCEFEDPWINPVWRGEDGTVREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG32</accession>
    <name>A0A9P6EG32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_869270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG32"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF25">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="5">
        <location>
            <begin position="108"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="32961" checksum="8EC8C2A9C0D311CC" modified="2023-09-13" version="1">MISQLLRSSTIYAIWLSSVAVAHPFRRQPSNSSLTAITTLSETEIDAFTPYTWYASTGYCQPSQVLTWSCGANCEANPSFHPLFAGGDGVNVQYWYVGYDTLLDTVIVAHQGTNPGKILPLVTDGALAMGTLDSTLFPSLPATIQVHEGFRNEQAVTAPNILMAVEDTLTQSKMTKVTIVGHSLGAAIALLDSVYLPLHIPGITFETVVYGLPRVGNQDFATYVNSNANLTHINNKEDPIPTVPGMFLGYHQPQGERHIEDNNSWVSCPGDDNSSTMCSTGDVPTIFEAKLSDHDGPYNAITMGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH11</accession>
    <name>A0A9P6EH11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_790986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH11"/>
    <dbReference type="OrthoDB" id="2756178at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="3">
        <location>
            <begin position="168"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="795" mass="89490" checksum="50BBB6714DB321B6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHC2</accession>
    <name>A0A9P6EHC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_283895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHC2"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="128"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="29931" checksum="B6AC2B8142FBD398" modified="2023-09-13" version="1">MTRMAFSFSPKNVIHMSPRAVWSIPVACCLIFGSLITLSHFFRISNSDALLFEGRITGSLSDAHGASFEWSKLPPRKDLQWVGCHLSFQCARLIVPLDYTDPEGRESTIALIRKPAAVPRDSTEYRGPVLINPGGPGGSGMAMVLSRGHLLGSILGPQFDVIGFDPRGTGQSTPKISFFETDVERELYEEPKSVDIADGTVSPLLSSKRLLNMLAAELDDGYLGHMNTDCTARDMLRIVETYGWNKLMYWGFSYGSVLGGSFAAMFPVTKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHC5</accession>
    <name>A0A9P6EHC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_905790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHC5"/>
    <dbReference type="OrthoDB" id="2745955at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="18739" checksum="19F004B0A6FA81D5" modified="2023-09-13" version="1">MVNRGMLALSLFLQGISIYLATMKLAMIIALTIYVSTSLTSALPAINMEESPSNIVVSTIKQSNVTISKLTVPSITTPNSLFKALILHLADSIIICTAVNCAGTCDAYALSGLKTNTCYTPQLSYESAYLFISSGSTPPYQAFASTSATNKCANPYLLPINKCSALPARAFDFFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHS2</accession>
    <name>A0A9P6EHS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_893129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHS2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040364604" evidence="2">
        <location>
            <begin position="19"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="15090" checksum="695EA52BB80FA578" modified="2023-09-13" version="1">MGISLSFILLGLACSTFAYPVSRDDSSGVTFVRRGCCPSKLTKPRPIKLPPLPDNRGGHAYDMGLYGPSASSAGRREDDRPVGLHGNMIDYGDPASKKPNEFKIPDRYVIPHIQQEHYKPEGHPLPGRLSKPPTHPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHS4</accession>
    <name>A0A9P6EHS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_765783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHS4"/>
    <dbReference type="OrthoDB" id="2756615at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="40260" checksum="E7EC10D50522FD54" modified="2023-09-13" version="1">MSNSSIKKVSIIIDDLRGDAFTLSGGGSWTVKKADQWFNGTTQLLESATDSTDPKQLGTLRMSFNGTSVALFGTTPPSSSSQTMSVSIDGSTASNTSYSDPNPQTYRQWYQSPVLADGLHNLTLGNIAGTALDFAVVTVGPDTPLNAQTVIVDNDDPAMVYSKKKGKWRRNMSSFNSGPNPDGFGYGNTTHDTTYVGSSFSYNFSAVSIGVYGVFSWSQVGSLSMEFSIDGNPQKKDFVVTADTPQLKSEVGQEQNFLFYSFDFLLPGVHTLTVNVTDCQNLAFSFDYLTYAPNFATLSAMPDVGIAASDDDGTSGDGDSEKTKSSKGVIIGAVIAAVALLLLITGSAFFLRRRKRRNGGAGLMGKVNSNSKYTPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHU1</accession>
    <name>A0A9P6EHU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_835363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHU1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="17283" checksum="9F8CFD3E52747C48" modified="2023-09-13" version="1">MSPRACLSSKSNELELARPYLPASLPWLVLIAGTTGTLGTSRPSISATASDKGFGKLDRDSGRGYSDDAKDQCSGNGIPEPNDENNLGCSVFAQLESSAKQEFQGRVGGLGKGEWRGWPTDYRWDGEYRYWAVLLVVETNVEVDIAVAWTGHLMIVINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIK0</accession>
    <name>A0A9P6EIK0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_852048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIK0"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="5">
        <location>
            <begin position="283"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="451" mass="49106" checksum="08DD4DB70246F7DF" modified="2023-09-13" version="1">MESYKSIKDLPTAWLSDVEVSVVGNGNDHPGPRKSGNTVYVYMGTVYQLYNFSKKNSLQVDLLVVDEAGQISLGSISLVLRSLSYEGRIVVAGDSEQLAPILSAQYPLLKAHSLFGSVLDCLMFPRARPLSARPPSPSFDESQGIVPTASPGTIVQLTENFRLNPDLSEFVSTIYSRKFKPQKAQAGELGAALSTVSHLRASDMGLNPEVFGKVQKFLGALSGVMKDRKSTPQSGLIAPEVQLPMTIASPRPGSPTSDLDPISLALIRLRTFPFNISYESHVQAEAAVAAALVASLRKCAPNDDIFVATPHRIQREAVKAALRVTTNPVEGLEDTFGKLRVGEQNKDSKEKVTVDTIERLQGSEASFVICLFSVPKSYSIDLAFLLERRRLNVAISRAKALCILISSDEVLCPSVKVLANEETAKGYAFLKAFQKRAWSFYLQLNADKVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIM2</accession>
    <name>A0A9P6EIM2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIM2"/>
    <dbReference type="OrthoDB" id="3243413at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="577" mass="63232" checksum="B97854134B7D8CD6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIR3</accession>
    <name>A0A9P6EIR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_764831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIR3"/>
    <dbReference type="OrthoDB" id="3062801at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="16338" checksum="973CE026C893BBAB" modified="2023-09-13" version="1">MVCHTAGDLAQREQFYHLHEISAHPKLPRFEKLLQSWDSFIETTVREWKSLNIVSTLLLTAILTVLQIPGLGDYRPIRYTALVALKCALMSMIFGVAFVIQFSSMRRRYIAAEWALVKSFVSFIGDCKLTILFIGSTEVAISIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIW0</accession>
    <name>A0A9P6EIW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Velvet factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_242797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIW0"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="16"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="20780" checksum="C3653FBCE296D6D4" modified="2023-09-13" version="1">MLPQYHHWPTSGDFDLRQYRVYELVVRQEPKQARMCGVGGKADRRPIDPPPIVQLRVVDPAAKTGGNAAAGPSRSMMSSDDDSPPGSPATRPYPDDSPDTNYAHSFLQNPYYFMFASLARPDDDAELHWLKDGRTRCTTGSVVSSLYHLKDPQNNNEDAGFFVFPDLSVRTEGSYRLKLSLFEVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIW8</accession>
    <name>A0A9P6EIW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_905890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIW8"/>
    <dbReference type="OrthoDB" id="10249612at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006742">
        <property type="term" value="P:NADP+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF6">
        <property type="entry name" value="NAD-CAPPED RNA HYDROLASE NUDT12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="263"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9529784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="482" mass="53107" checksum="D87BB3547C88D99E" modified="2023-09-13" version="1">MANPSQPHVNLYGGSPLNRLSWLRTSQSFLNAIIASQNARWLIFKAGHPLMLSEDSSKRSPAYLNTVDMISLLGPEPIFGQGKDVGELLADVDAEVDKHSPVEAVRHRGLRIVFLGIHEEGTGGRTHGALPTSELSDPQEAIKRLGGTPYFTADISELEKTKEELENFLNETSLAREGKKIAWTEPRSLMSSLDSFTAAVMASARTQADWNLRNKFCPGCGSPSYSMWGGWKLACNSLLPWVDNSGRSKPCFTAKGLHNFTHPRTDAVVIMIAIDETGDKVLLGRGKRFPGKFYSALAGFIEPGETLEDAVAREMWEEAGVHVWDVKYHSGQPWPYPANLMVGFYARADSTQPIRTDLDNELVDARWFTRQEIQQVLNHVDGTRFKKEDVRKMVEAFDERSNTEGGENPKRSELEPVASACTPCEGPAVTTPVKEDSNAPPFTVPGYTAIAGVLIRDWADGKIGFPRSTEGVNVNGAHKINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIZ4</accession>
    <name>A0A9P6EIZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIZ4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="68029" checksum="0B8ECBD331AF2D45" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ02</accession>
    <name>A0A9P6EJ02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_811900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ02"/>
    <dbReference type="OrthoDB" id="10249988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000013">
        <property type="entry name" value="Coatomer subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="8"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9529780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="185" mass="20946" checksum="5C8DD89FE7C27BD2" modified="2023-09-13" version="1">MNLSLYSIQAFIVLDTEGNRVLAKYYRSKSNPQGETKDFQHLKEQKTFEKGLWGKTKKPGGDIILYDSHLVVYKHSLDLILYFVASPHENEIMLSHALTCLTDALTMLLRNSLEKRGVLENLDLILLCLDETIDDGIIVDTDATAIASRVTRPRADSTEIIINEQSIMTAYQTMKDRLQQGLRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJD5</accession>
    <name>A0A9P6EJD5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJD5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040194428" evidence="2">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="11150" checksum="DE8588A91170A75A" modified="2023-09-13" version="1">MRFSCVAIVITLAFSAVPSTFSTPVPERDGGNSNSLPSGMQKQAINNELPYDGDMSPSSVASQANATQPASAAATTGGVSVGSTSRALSHSPATAAWSAGALTAAGLVFSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKT7</accession>
    <name>A0A9P6EKT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_881264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKT7"/>
    <dbReference type="OrthoDB" id="61370at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040364605" evidence="2">
        <location>
            <begin position="25"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="23663" checksum="78193D145A7DBDFC" modified="2023-09-13" version="1">MRATSYLLAFAAVTLTLILNIVSSKRVDWLVVRYKENAIRTKVTFFYGLAERCQETISQIPTPSGDGKFTYRSYECRPFPQQDYDQCDGDSFCTAWRAAYYIDQVAIGFAALALAGILIGATTHSRRRRVWRSVVGLVLVAALCQIAVFAIITDVFEEAPFPALDTARPALGYIFHFLAWLLNILITLGILVAGVSADAGHAWALGDRGYEPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELT5</accession>
    <name>A0A9P6ELT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELT5"/>
    <dbReference type="OrthoDB" id="2739946at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21241" checksum="D327F4F52848582A" modified="2023-09-13" version="1">MTRSQKAPSRREQFNKSVRAKAQSEGTTFRDAATKKKAALKEKPEGAPSTETERRNPGRSDGDRWKGSQFITGKQIGDQHSEFYDSEDDQNELYDNTSDLKGGSAPMVNILDLAKPAKRRGVAKHFELIPKTKRVLSLASTHEGDDFDLVSNESTSWLDDDTWEDLDNLYDHDAREEAMVTYSDVLRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMX7</accession>
    <name>A0A9P6EMX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMX7"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="94" mass="10006" checksum="6081063118993F65" modified="2023-09-13" version="1" fragment="single">MGQTGLTSVQDFVNSWTSQEKNYIPSSDTFPANSDEVGCFTQVVWKATTKLGCDCTPCSSGFTLGICVYEEPGNFGGQFSDNVQAQVAGSSMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMZ2</accession>
    <name>A0A9P6EMZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">THO complex subunit 1 transcription elongation factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_760130</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMZ2"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="12">
        <location>
            <begin position="681"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="518"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9532095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1069" mass="118679" checksum="E6D1956448CECF66" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPD0</accession>
    <name>A0A9P6EPD0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPD0"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="39"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="635" mass="72005" checksum="237F549C00150398" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPD1</accession>
    <name>A0A9P6EPD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Postreplication repair E3 ubiquitin-protein ligase RAD18</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Postreplication repair E3 ubiquitin-protein ligase rad18</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 18">RING-type E3 ubiquitin transferase RAD18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CPB83DRAFT_757682</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RAD18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPD1"/>
    <dbReference type="OrthoDB" id="9049620at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097505">
        <property type="term" value="C:Rad6-Rad18 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000172">
        <property type="entry name" value="E3 ubiquitin-protein ligase RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004580">
        <property type="entry name" value="Rad18_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00599">
        <property type="entry name" value="rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="21">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="110"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="351"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00074353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00082369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF9533516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="42256" checksum="7A1FD2D6D5A94ACD" modified="2023-09-13" version="1">MNLMDVPDPTDFPVESTAPGLRSLDGSFRCDICGELYDAPVTISCGHCFCSACIRTALANKQECPSCRKVANEAHIRSNPVLEMVISDWNKARPFILGLLKNKVFSPNAQDNGISKKRKRSSARLSSSDAVITGTSRVTLPPSPSKRHRAKSKSETPMEITTLSSDSDEGGPSKPSGHALKSNDLVECPICAKRVNYSQLNGHIDNSCRDTTTNKSSAEGWSKILGGTKTKQKGKHKSKHSDSDDEYPLPIQSYTTLKDRQLKDMLQQYELPVTGDRPIWEQRHQRWVTIYNANRDKSVIHRKAKAELRRELKSWEEDLAKRKKGADHTLVDDPISYQITHKDEFAKLIQTARANKERKSSPITASSPTDLASSPSDPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPY7</accession>
    <name>A0A9P6EPY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_890750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPY7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="31895" checksum="6B772E2BA2EA116A" modified="2023-09-13" version="1">MLPLKTRYLRTVSTTCSLTETPPSTQRAPHSKSSVHLTILRETSESVDLEVLKAITDLTLALLAHEVIFLRLSLFDVFHNTTIGVAALSLGYVMTNASFMFIWSSKTYQDELSTIVKAMQTIYEIANVPAPEYLMGSRFFRSSYWTIKQQLKIVKVALSQLEGSPFRVKDMCEDNMKRLLECFEKRRQRENTPDIIQCVSVPGPLVPEQSEQRQDSGMYFPDINVHTAKPVIYYLHQLPLVSRSSKNADTLTFLGNTTMNANAPQLMLTAQTIYNTTISVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQB5</accession>
    <name>A0A9P6EQB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_873879</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="205662at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099070">
        <property type="term" value="C:static microtubule bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990571">
        <property type="term" value="P:meiotic centromere clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000022">
        <property type="term" value="P:mitotic spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000019">
        <property type="entry name" value="Cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000068">
        <property type="entry name" value="cytoskeleton-associated protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000063">
        <property type="entry name" value="Putative cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="652"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="930"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1251"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1515"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1875"/>
            <end position="2119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="885"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1162"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1746"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1797"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2105"/>
            <end position="2272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2556"/>
            <end position="2623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2739"/>
            <end position="2759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="885"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="910"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1176"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1198"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1212"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1746"/>
            <end position="1772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1828"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2149"/>
            <end position="2165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="2166"/>
            <end position="2183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2198"/>
            <end position="2211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2261"/>
            <end position="2272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2577"/>
            <end position="2617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2759" mass="301631" checksum="6D12EEA894D87493" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQJ0</accession>
    <name>A0A9P6EQJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA polymerase epsilon subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA polymerase II subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_843882</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in DNA repair and in chromosomal DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQJ0"/>
    <dbReference type="OrthoDB" id="10254730at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000799">
        <property type="entry name" value="DNA_pol_eps_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="7">
        <location>
            <begin position="290"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="540" mass="61133" checksum="B41D0D8C1E0B9BD9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQM1</accession>
    <name>A0A9P6EQM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_805218</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQM1"/>
    <dbReference type="OrthoDB" id="5580488at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000051">
        <property type="entry name" value="F-box and WD-40 domain-containing protein MET30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="155"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="337"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="384"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="424"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="521"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="597"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="620"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="660"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="693" mass="76707" checksum="70D93B1EFA964614" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQU4</accession>
    <name>A0A9P6EQU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_539663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQU4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8229" checksum="5DD6CE83442C3607" modified="2023-09-13" version="1">MALSSCLSPHLGFLVIHSSLFPFTFLSYALFRRFLSSSSSTSSIIFHCLRVLHLSSLSFSLHHRMHLFCSHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQV1</accession>
    <name>A0A9P6EQV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_805554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQV1"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="59"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="32687" checksum="1E5F03BAFC0C117D" modified="2023-09-13" version="1">MPLTVLEAARVIGNPSVYEDENVHAIYEEIAEHFSSTRYKPWPIIASFLSSLPCGFIGLDSGCGNGKYLPLPADRPGEVWTLGLDRSGNLLQIARAAGATGVKREVLRGDVLETCWRKGVFDYAISIATIHHLATEKRRRCAVKRLLEAVSPSHGRVLIYVWAIEQDELSKRKVFDSSSGGVAPHKGKDVVVPWVLSKEPRGKNKNESKGHEQTPPDNEEPKVYNRYYHMFAKGELRALVEEAAKELNLSITMEQNAEGRSRGLEIVQDGWERSNYYVELKLWESIKPRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER39</accession>
    <name>A0A9P6ER39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_845221</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">High affinity uptake of sulfate into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER39"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902434">
        <property type="term" value="P:sulfate import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000046">
        <property type="entry name" value="Solute carrier family 26 (Sodium-independent sulfate anion transporter), member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="10">
        <location>
            <begin position="530"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="676"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="758" mass="82210" checksum="66544106E543E830" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERG7</accession>
    <name>A0A9P6ERG7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_888714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERG7"/>
    <dbReference type="OrthoDB" id="3066012at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="34192" checksum="AC151B3DEB962F6B" modified="2023-09-13" version="1">MALVRRQAAGSQEPAANPAPTPSASSPSAPVSNATSTSVTSSATTTSSTSRTLPTTSSSSSSSSVMTSTTSSSTSASTTTLPPTTSSSVLTSPSISATSSSLPSPTSRPTLTSTKAATTIMAPDNIVPLGTTTNDVLTSAPPVSNAITGATKSGFMQNKGAVAATFTFSSLIFIAALVAIIVAVMKRRNARKETALHDELFISYVEPADYHSNYRSDSPEPSLNDTPMDPFSRREVVYDAAPEMSQGHSSSNHSHYSHTIPVVQVTPPVQHPDYYNARKYLPPSQTQTAASAVAVKPTTTARLKHVSAQSGYQQSVDSFYGAEQPSGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESY4</accession>
    <name>A0A9P6ESY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAD4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Outer kinetochore protein DAD4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_755605</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESY4"/>
    <dbReference type="OrthoDB" id="5516652at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013959">
        <property type="entry name" value="DASH_Dad4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08650">
        <property type="entry name" value="DASH_Dad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9534810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="7930" checksum="9F47481D07B06E99" modified="2023-09-13" version="1">MENPHAERQAVLLERIVKNTSKCTEMILELNHCLEEVLRANASVKTAADLATKYRKNVQYNLEATKGKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETX7</accession>
    <name>A0A9P6ETX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETX7"/>
    <dbReference type="OrthoDB" id="3217643at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="467" mass="49739" checksum="E0C3AF5692A3D465" modified="2023-09-13" version="1">MCYSAGSISQAVNPCPMCKVYSHTKCPHIRETCRNRTAHPRMDVLYLKNAEVESFNGCGYCKWANQEPPPKQTGYNNPGWPGCCRAPYQNEINQIPIADWHAVSIVHKVPIPSAIEDILNSFSLPPLPFKTVTNKQPMSPTGSLRSSTKSSTSSSRKTSGAAAFNGSGNNVASSGTPSKSNGASSKPSNSTIGRGRQGTIVAGSNAASRSSSSHALPTSTSAPNSPAMAENGHARRKSSAADKEHKRNGDGSNSNHSSPSRRSLEVENSLTTPRRVSSVRRPVPTPATTSVSVSKVIASDTREIKAHDGLNGTIGRRGSSASTSNRPSSRTGDSNFLLPRSSKADDDCRSSSSGSSDGMLSDSTMRSEGFTDYLSDESEEELQRQAEAKAAVVAQNQMEELEFKMARQQLAHVGLKPPKSWTETNSPPVSPSKKQHSPMPSPRNPNIPTHSFAVAATAMMQTGQARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUA2</accession>
    <name>A0A9P6EUA2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_888173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUA2"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="52183" checksum="7ED948B6EDCCDF28" modified="2023-09-13" version="1">MPEPALDRPTSARWVVIDDTDPRISYTESVWSAQKLVINEDQGTSGRAYNDTLHVLTPLEGVSNRGTAGVSFNFSGVAVEVYITNNLPNITGANAVDCWIDGVQIQINIQPNPSGNPINNYMLCDASNLVDRLHEVLVVPNGSLDSFFFDRIQYRPSANASLENQVLYVDSFDPSMVFGDGWKGTDGAWYSYTSTRGSTFEFEFTGISMAWYGVITAQDSGSPSNFTYTIDGGSPQLVNLTGHPVGSPTLQNQKLFEIPSLSMGKHNLSVVYNGDNTTTALTLDYIYIQNGTFPDASPTSPPLTNQTNQGTKNKSKHVGPIVGCVIAAVLCIIFLALSYLYYRRRRRISKGQIDNPDRYSTIHIEPFPIQTIDQPFVTEGPHLAKGGNVDSDDPETPLRSPRSPTLVKITGVKSGNPSSVALPLASVPLTQTSLPEVDTNYAIEAVPPSGVIRHQDSGVRMREERASGMVELPPEYTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUI3</accession>
    <name>A0A9P6EUI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_801518</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUI3"/>
    <dbReference type="OrthoDB" id="10260946at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057544">
        <property type="entry name" value="Beta-prop_SPT8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23798">
        <property type="entry name" value="Beta-prop_SPT8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="5">
        <location>
            <begin position="145"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="275"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="5">
        <location>
            <begin position="450"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="391"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="631" mass="68204" checksum="8E21B3986D69CC88" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUU9</accession>
    <name>A0A9P6EUU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NADPH oxidase isoform 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_901119</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUU9"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000091">
        <property type="entry name" value="NADPH oxidase (NoxA), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF39">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="236"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="559" mass="64018" checksum="397D95BAD503ECDD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV01</accession>
    <name>A0A9P6EV01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_841989</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV01"/>
    <dbReference type="OrthoDB" id="2146436at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040356393" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="24"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="22"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="22426" checksum="2E09239F423D0F66" modified="2023-09-13" version="1">MRSTTIVLAILSYLLSTFVGVNGHFKLQYPPPRGEFDEDNEPNFCDGYPNPSNNRTIFPLSGAYFSLESEHVKWTAGVLVSTTQNVSAFDQFSQVNSFFQLQGEGNFCIPLDFSKSNMTNLQDGQNATIQIVFNGGDGALYQCADVTLSSTAKIASSIQCTNSTSSGSSNGGNTTGGGSSGPKSATVAMSVQTHLSMFTIFAALLGEYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV79</accession>
    <name>A0A9P6EV79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_4619</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV79"/>
    <dbReference type="OrthoDB" id="687049at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 15" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 14" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="16">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="388"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9535329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="503" mass="54392" checksum="FF9BC50F96EA1BDD" modified="2023-09-13" version="1">MFYCAISGEPPQDPVVSQKSGKVYERRLIVKYINENGTDPITGDKLEEADLIAIKASPETAPPRPPTHTSIPALLHLFQNEWDAQVLATYSLQQQLHATRQELSYALYSQDAARRVIARLIRERDAAREALGNVQASMGIIPAATNGEDVEMEEGGAVEGALPANIVAQIDETHQALSSVRKKRKPAAGYATSAELKEFKPTHTIPSLHSASPAGITALALSQANPTQFLTGGNDKSIQLYDKATDKVLATLKGHTKKINHVAFREREGENTILLSAGADKIAKAWAHDAASGEYIPKATIRTHKGELSGLAVHPTSSFFVLSSTDKTYSLHDVSTFSQIFRSGPSEEAFTGLSVHPDGCLIGLGTPTSTIQIYDIRTGAIAASLAPPEGSPFTVNTLSFSENGYHLLAPNSLSTVAVWDLRKQKSTHTINLGDDFKINKVLYDTSAQFLGVAGSHGARIFAHKTWDELLRLDEGGEVSDFTFGEQGKEIWGATGREVRIWGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVH8</accession>
    <name>A0A9P6EVH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent RNA helicase SUB2</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">ATP-dependent RNA helicase sub2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CPB83DRAFT_842249</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the DEAD box helicase family. DECD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVH8"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000111">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000168">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase 56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="21">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="73"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="276"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="17">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00040402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF9535737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="425" mass="47671" checksum="CC3D8B92B05CEF45" modified="2023-09-13" version="1">MSGHDNEDLIDYEDEHDIPTGGAATGDDEGKDKKNFSGIHSTGFRDFLLKPELLRAISDLGFEHPSEVQQECIPQAVLGMDVLCQAKSGHGKTAVFVLATLQQLEPVNGGVSVLVLCHTRELAFQIKNEYTRFAKYMPDVRVSTFYGGTPVAKDAEILRDKTKCPHIVVATPGRLNALARDKFLDAKNVKHFVLDECDKMLEQLDMRRDVQEIFRATPHHKQVMMFSATLAKEIRATCKKFMANPLEIFVDDETKLTLHGLQQHYVKLEEVQKNRKLNDLLDSLEFNQVVIFVKSVARAIELDKLLVSCNFPSISIHSGLQQEERISRYSAFKAFEKRILVATDIFGRGIDVERVNIVINYDCPPDADSYLHRVGRAGRFGTKGLAITFVSSDGDTQVMSAIQSRFEVAVPELPEHIDPASYMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI07</accession>
    <name>A0A9P6JI07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157973">
        <property type="protein sequence ID" value="KAF9521926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI07"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="28351" checksum="221A2C17CEC82BB1" modified="2023-09-13" version="1">MTNHFDVNQNNTQPSMPPPTRTSSPTQNHSFFFSSYNRQDSSPDNSISHYTLTSNVLFSSSDEESAYPELPPRLPTDTDASGGILTDKFDSLWDSSLGLLSSWSSVSLAFASESKSDTLTLVWKSIALKCISFCIVTSASSSQAYTFITPQLAFKERPNVIELFTKDFKAINWAVNFNGVKFDLTRIQGWYATSYTVEVFAFDREGDYIVEATNVMEPFVINIPTSLIDPQFFYQTSPHPSVTCQKHTLWYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI35</accession>
    <name>A0A9P6JI35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_911574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157967">
        <property type="protein sequence ID" value="KAF9522001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI35"/>
    <dbReference type="OrthoDB" id="2501483at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041539">
        <property type="entry name" value="CxC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040898">
        <property type="entry name" value="CxC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18718">
        <property type="entry name" value="CxC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18721">
        <property type="entry name" value="CxC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC5 like cysteine cluster associated with KDZ" evidence="1">
        <location>
            <begin position="118"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="CxC6 like cysteine cluster associated with KDZ" evidence="2">
        <location>
            <begin position="346"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="668" mass="76683" checksum="CFB5436ED238BD44" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIR0</accession>
    <name>A0A9P6JIR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIR0"/>
    <dbReference type="OrthoDB" id="2104739at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="117"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="32926" checksum="A3BB9E20635EED7C" modified="2023-09-13" version="1">MDFAMNHRGKRYIAMAIMASQDTPNPADFFETLAFIWLTRLLYPIKVLGLQGEGLTSEDTTPQHQEIASLAGKASHGDQKALRLLLCQRQGEKFAVSDSYSDEASPAMVGDAVVAPLIASRIFPFSSNDFKDYESASGVDGLMDSQYSIYLKKRAVDTWDMLIAWSSFDIQKLAESEINGPANAVLLRADLDPQFRKFQFWFEPTEQPNAYNLVARRNTGYNKKVITFANCHDKPIAIPDPKILGLHAAFANVLNASGAGEYIDSCWRDMDDIRVLSPDGATSLHSLNLALPRLVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIT8</accession>
    <name>A0A9P6JIT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rho guanine nucleotide exchange factor scd1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_899456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIT8"/>
    <dbReference type="OrthoDB" id="1594986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13246">
        <property type="entry name" value="PH_Scd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010481">
        <property type="entry name" value="Cdc24/Scd1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033511">
        <property type="entry name" value="Cdc24/Scd1_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06395">
        <property type="entry name" value="CDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="214"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="4">
        <location>
            <begin position="924"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="565"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="621"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="817"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="867"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1007" mass="110536" checksum="5FDA4140B1F93051" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJA4</accession>
    <name>A0A9P6JJA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJA4"/>
    <dbReference type="OrthoDB" id="3212378at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9115" checksum="09B08A8672C0BD8F" modified="2023-09-13" version="1">MLNSGNVAPTNATQTKERLYTQLAGSLGRMSRAISQTADLCEQLQVDLHAMRIFAGLDAAKFMTIAGELNKETEGNEEEQVGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKF8</accession>
    <name>A0A9P6JKF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKF8"/>
    <dbReference type="OrthoDB" id="5311491at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="45713" checksum="24D27E258E447396" modified="2023-09-13" version="1">MVSQNVAVLPSGLELAYTDSGAVSGSSNYTTLILVHGCGFNARTFETLHDHAATFNLRTIAFQRRDYPGSTPFTDDEITEIQQGSEEYLSKTQNMMIDFIRYVVEKLSIPAIWKLSGQEAGKLDGGIALLGWSLGSYFPLALFSNPERVTPESRKILGKYLRSLIIYDSPYVALGFPLPSIKPSAGEEESVSPSDFPAAVSSYFDQPDNWAGDLDQLDQRSKTEKNIWSDWTEEQRNKYVTMSTLLRCEFPTFAGPIQAHFLKNTQKALYDETLAQEYLPDLSIGVLSVGRTLWYCRWMMWHLVQTNREKLDEGKKIRELKTAHLQQYSHLAHMEDPVLFLVQRYKMQSCCVLGFWSFFVPFKEPRILTLSERNVKSKWLSWLSSAGRVGKFPDRRSVIQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKN4</accession>
    <name>A0A9P6JKN4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKN4"/>
    <dbReference type="OrthoDB" id="2974017at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="24254" checksum="18A8DDA0982999DB" modified="2023-09-13" version="1">MGDKYIYYQIFNDNGALDVKTPVDASDSTTGRIHTNQITPPRNAGNLKRIIAKREGFPVDPNTALFFKTDDEAPAEDNQMIGFSSEAQFGGDKENPIGVVFQGDVNPSSKPSSSTNLSGGWSIEENVDGHPMFRGILVLVMRSATTFDGFCQQSNVYAGGSYMSFPISNGNIVDGNVEWTTGGAGWGNTNNVVKVAVTLSADGKSMTGSVAHVSGGTIGVPDATYRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKQ9</accession>
    <name>A0A9P6JKQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="9">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_877730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="9"/>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKQ9"/>
    <dbReference type="OrthoDB" id="3781271at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040432803" description="(4-O-methyl)-D-glucuronate--lignin esterase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="12">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="468" mass="48707" checksum="23397F4FE67944F8" modified="2023-09-13" version="1">MAIKVSLITLALAVSVFADQPLWGQCGGMNYSGSTTCASGSACIKMSDWYSQCQPGSSSPTADPPAPSNPTVTPPAPPVTTTVDAPTSTAAPPSTGAPAACSPLPSNITLKSIPKLPDPFTDISGNKITTKAQWACRREEISQLFQKYELGTLPPKPSGLTATYSGGTLSITATEGGKSISFTASISGNTGTKVPAIIGIGGISIPRPNGVAQINFNNDDMAAQQNTGSRGQGKFYTLYGSGHSASSMMAWAWGVGRVIDALEITTGHNIDLTKLAVSGCSRNGKGALVAGAFNERIALTIPQESGSGGAGCWRISDAMMAKGINTQTAKEIVGENVWFSKSFESFVNTIPTLPVDHHLLAALVAPRALLIIDNTGIDWLGPQSVFGCMKTANKVYQALGIADSMGVSQVGNHNHCAFPSNEQGDLTAFINKFLLGQSTNTNIVKTDGANNAGFVENDWVDWTTPTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLA8</accession>
    <name>A0A9P6JLA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLA8"/>
    <dbReference type="OrthoDB" id="3044119at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="177" mass="18743" checksum="B60E6CDDD88C076C" modified="2023-09-13" version="1">MSKQPPPRSPTQTTKGKKVAKTPLHVPPGFVLATATDGARYAAPDFMISAAELAIEAEQMKQTLRTGQAAGGPFPHNYGPAVSMGDAPRIPCPPDPGLTERELLVLHAEVLALQNQLGISYKDAAHRLYLAEAKAAFVAAEAITSIRTMSSELDGGLQHIIRQGVAASDPNHMSVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM64</accession>
    <name>A0A9P6JM64_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM64"/>
    <dbReference type="OrthoDB" id="3268127at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30168" checksum="56F668A27F68F098" modified="2023-09-13" version="1">MNSSPLAESPGKSSPVLAAQARRKSQYKTLSPMTPLSVRSTSGGRQLSHRSVSEGTKKAGTSASGSGGDDALRERFRAKCIERAVREREKAIRGKRSLMPRQPSSDDYAMEDDDSEDDEAIMQDELFRRIVANAERKEKHAYRLSYAREVGSSFDPDLEEVDRLEQEFTAPDTMRSRSVSVPLAGPSTAASGPPSSVHPEDEEDIPLDFEDLNDEQLQAYAEELASREEFDDIPEDFHWSDFDDVEDLGNPIEDPKTPVPHNTMEDDMDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF1</accession>
    <name>A0A9P6JMF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_506026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF1"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="32"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9526051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="37736" checksum="3576486AF4DAAC7A" modified="2023-09-13" version="1">MASISKAEKSYIQAGLLADPPSRADGRSKNVFRTISLETGVAPLANGSARLSIGRNPHDGSGGTEVLAATKLEVEDIGPGSQGLDSGRIECTVSCSPAAYPFLSSNALDELQYDYTTIMSSTLTHPSLRPSNISILQGKKSWLLHLDVVVLTDSGNAFDAMFMAARAALCDTKVPRTRAVEYRASDSKLKGKTSSGGIMGAVLDASSSKDMDVDVDVMESSSFNTRVHSKATDFELPDYWDEGEILDGKGRWPICITLNIVSATHFLDATTPEEASVSSRLLLMFSFPSDSSTSKSQLYGMRTLGSGEFSVSQLSDLLKEGESYAKEVWKALNSQLDEETALKLKEMKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMY5</accession>
    <name>A0A9P6JMY5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_770642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMY5"/>
    <dbReference type="OrthoDB" id="3163890at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF4">
        <property type="entry name" value="DNA ADENINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="18709" checksum="A3AB66E2267E901B" modified="2023-09-13" version="1">MNFKGIKPFYLHALQDEEAHICPVRAMSEWIEASKITKGYLFRKMASGDRPSQNDSPMTSEQFLEMFRNNLLDINIDPIPYGTHSFRRGGCQYLASQRRWLLRDICEWGGWSTDFSNLTIVRYLISWNDVPTKRREDFFDPHRRPVIFCYQCGRSCPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNI9</accession>
    <name>A0A9P6JNI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_896002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNI9"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF166">
        <property type="entry name" value="LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="429"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="555"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="660"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="561"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="715" mass="76003" checksum="434043257F239C7E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP05</accession>
    <name>A0A9P6JP05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 11">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_856478</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 11"/>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP05"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF41">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="251" mass="26838" checksum="D4C353F6612B1AAE" modified="2023-09-13" version="1">MTRQFFVGGNFKLNPTSLTASKSLIDVLNKGDLDPNTEVVIAPPSIYLLSVLDSVRKEVKVAAQNAYFKESGAFTGEISPKQLVDAGIPYVVLGHSERRTIFHETSELVATKTKAAIEAGLKVILCIGETLQEREAGKTAEVCEAQLKAVVDGIKEADWSKIVIAYEPVWAIGTGKVATSAQAQQAHADVRSYLAKAVSTSVANETQILYGGSVTAANCKELAKQQDVDGFLVGGASLKPEFIDIINARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPS7</accession>
    <name>A0A9P6JPS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPS7"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="69"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20618" checksum="C4450BFF2B21A036" modified="2023-09-13" version="1">MLALTDTDNTESDPSHLPKLILCHTYEPQPSNLARRGMARKQANYLTVTAMHLYREGLRGLIRHRSLDSSLLMRTPIDILFEIFRNLHPIDLAHLRSASLIFDETINCIGNILWKASFDELASEMSIPSGISASKWAHLLFGPSICEECGAVHAPFNVVHSHRLCHECHSRRFVHMFAASLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPT8</accession>
    <name>A0A9P6JPT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_836170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPT8"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="29464" checksum="9370B9168CA0AED6" modified="2023-09-13" version="1">MKQAYYLESIELIKKFTGASKVVLFDHTVRRRRPGQVDDSPSRRQPVEFVHVDQTTQTSITRVHRHLPADEAPKLPEEQFQIINLWRPILHAASDQPLALCDYRSVEPEKDNFPLALWKYLRGMTSDEIVLIKSYDSIQDGKMAIFTPHTGFKDPSTPMDAPLRESIEVRALGFCDSQTSVTQDDGAGVSKLSPRRATPSFPRLSLPPAHTMRHAQGLGHFIINSTRELGLAPVKFHGSSLSATFSPPATMALFLPVAPLVAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQR2</accession>
    <name>A0A9P6JQR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQR2"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="284" mass="31941" checksum="7E4D9382F6FCD63D" modified="2023-09-13" version="1">MPVSRQRLCVNLVHVLFGVYIWETFTSFDFEWMLFYGKKKCRWPLVLYVLNRCCTCTALIVTLFVISNGQAHCREAFRAMDFLTHLALVLASLTLAIRALAVWSWNKMIMVSIVSFVVARLSVCIYHTLAIKINDVPGVGCVMPGQVDPSRTAIYIAAVVFDWAILSLTVYKLKMRMRAISLVPVNKCSCLRILLFKQGMIYFVLAFLTNLFVVILSNLHLDMNILLGAASCSAVVCSIAAGRLARWLYNNDCNQQLIISVNSLRTLPTAPLSRIKDNMDATLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQZ3</accession>
    <name>A0A9P6JQZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_834869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQZ3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040177277" evidence="2">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="120" mass="13084" checksum="F7E994A99DC3C3DC" modified="2023-09-13" version="1">MLFTKLFFVAAAASGVFALPLRTTSQGLESREIQEDLYYRDVAAIVEAVLQARGVLDKHEVPDPVLKGKSREIIVDHGPTNDKLTKGRGDLAPKPLRLMTDKHGASKATTLKTIEEQGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRW7</accession>
    <name>A0A9P6JRW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_834561</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRW7"/>
    <dbReference type="OrthoDB" id="3863715at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042246">
        <property type="entry name" value="ZCCHC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46242:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46242">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="351" mass="37984" checksum="87F25861276E4DAA" modified="2023-09-13" version="1">MTRITNFGRKRTHLEAGFAGSLADDISATASISNEASTSAQTLDDLKNEARVIATEEPTKKKRKKRIRTPMSKRDGYAAKLKEAAEQDVGTDGGASNLMGVAKVGVDNTEKPKPPTMKKDGPKKKNKKKDRQERIKSATEARRLKRVQDKLTDTICFACREKGHAARDCPKPLVSGENAEGSQSNSKRPGVGICYRCGSSKHSLAKCRKPADPSNPYPFASCFVCSGTGHLASACPQNAERGIYPNGGCCKLCGDKTHLAKDCAVKRKVHDPMAVIIGSNANTSTGQAGADEDDFHIYKRTSNEIDHAEKQQERLAKMRAMENRKGVVSGSVVAGNLQPPQSKQAKIVVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRY4</accession>
    <name>A0A9P6JRY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor G, mitochondrial</fullName>
            <shortName evidence="8">EF-Gmt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Elongation factor G 1, mitochondrial</fullName>
            <shortName evidence="8">mEF-G 1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Elongation factor G1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MEF1</name>
        <name evidence="10" type="ORF">CPB83DRAFT_905070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRY4"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04091">
        <property type="entry name" value="mtEFG1_II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000003">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000029">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000022">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009381">
        <property type="entry name" value="PRK12740.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636:SF2">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="66"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="152"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="206"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="774" mass="85705" checksum="75885E5F58E73FEE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS66</accession>
    <name>A0A9P6JS66_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_787637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS66"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="62427" checksum="F1819B22AC314B62" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSE4</accession>
    <name>A0A9P6JSE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_834045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSE4"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="73"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="247"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="47144" checksum="E631DF561B8EA541" modified="2023-09-13" version="1">MASRNTTYTALTPEYSAFENLPVPRGLEPIDEEQEDVEAEGRVSYSGEEPTTKRNWFRDLRKRIWVDFIEKNAGLLLVAVAQAFFSFMNVAVKMLNRLDPPVSALQLIWVRMMITYVCSVSYMYFAGVPNPFLGPKEVRHLLFLRGFVGFFGLFGVYYSLRYLSLSDATVLTFLAPMFTVFTGAFFLGENVSTRQVFAGLVSLVGVVMIAHPNFLFGSASDTPIAIERVNPISVSAPIVTPAERLMAVGVALIGVLGATGAFTTLRAIGKRAHPMHSLTFFSALCVIVSTIAIVVTKTPIVVPSRMEWLVLLLMIGMFGFIAQIFLTMGLARETAGRGTMAVYTQIVFASILERLVLHIVPSALSVAGTVLILGSALYVAVSKHSSPPTSGKANHATELQEQPLPGQTEMEEGLLAEHDFDHNQQPVIGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSU1</accession>
    <name>A0A9P6JSU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_132098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSU1"/>
    <dbReference type="OrthoDB" id="2978948at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="18420" checksum="32E8C3A2F9E8B1ED" modified="2023-09-13" version="1">MEVSCHQWGKSGRSYNFGWLLRCCFSSSDVLPLLFGARWHSWPRVKSQENISPLASVACTFSCPEVDDLSQPLVKRPGAIGFDSYYSIFECRYASPSSEHACFYEKSSGEQKLASVNNNCPESAVSCTNNDGRLSEFSNPDKEEVSPWIEFGRVQLRFIEHGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT16</accession>
    <name>A0A9P6JT16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_121942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT16"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="16758" checksum="C972F21EF22E45C5" modified="2023-09-13" version="1">MTLPLNMLTIATNSKSQAILSFDPQTCSSIPKTLISLHTKAIRIENQVSRYTNALRGKAGCPRMTGGHRDRHRLRNFVVSHPPMLRQTTQRIQETSTMSYSNDVSPYHAASADALNLALFQSLTGNTLEKRVVHFCLSGSRAFIILIVGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTT5</accession>
    <name>A0A9P6JTT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTT5"/>
    <dbReference type="OrthoDB" id="274726at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9824" checksum="7D9A1048E9053087" modified="2023-09-13" version="1">MSSELRYTANTQLEHLHARYTGTGHADLSKYEWLTHQHRDTLSSIVGHPTLTSYLAIADGEAIGRVKFEMTERMLQPCGPPPKKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVL5</accession>
    <name>A0A9P6JVL5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_902703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVL5"/>
    <dbReference type="OrthoDB" id="4646138at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="148" mass="16842" checksum="6AE4CF1A5E1E3A4A" modified="2023-09-13" version="1">MSDSTVATESLVRKFITLFGSHKFLDTLPLAAPTATWRISGIKEQNVAAGLKLFKEHIQGMLDVPKEILNWERLEIDVVDLLVDHKGEKAVLEVVAKIKDDDGVYRYTNDAAFIFEVKEGKIQSIREYMDFAPVAKYITEKREREGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVR1</accession>
    <name>A0A9P6JVR1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Argonaute-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_804057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVR1"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="292"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="562"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="916" mass="100838" checksum="2C4AA2CA2DB08855" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWF7</accession>
    <name>A0A9P6JWF7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sensitive to high expression protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_756150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SHE9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWF7"/>
    <dbReference type="OrthoDB" id="5595506at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008839">
        <property type="entry name" value="MDM33_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961:SF3">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05546">
        <property type="entry name" value="She9_MDM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="426" mass="47357" checksum="04BDA0BF054E577F" modified="2023-09-13" version="1">MLSSSRLKPTQLWRSFSTTKSTRNIQRPSQYDLNLTETIHQAPNSTSTKSSEPSTPDIRLPAPDANTVPILPSSPSISSSASVPLPEPSSVSTLQSTSTRKPESASEHLSEYDPAILKKRLREWTEQVAITLRHRADDFTTRSKTTFSHLGAELNKVTGYEEIEALKKGVSVQEQRIHDSRQAAREAKKAYEAAVLQRADSQREVNDLLQRKSIWTAADVARFTELVPKDHSHQQQEEKTKAAADEAEEIVEKEFAKLMRLILARYHEEQVWSDKIRSASTYGSLAALGLNMLVFIMAILVVEPWKRKRLAQTFEDKIVQLSSENGRKLEESMKILESQIGQQENLITALKGDVLNGVEQMALRVVAPVVVVDELPLKTVNKTDTIRTEPRISHGSLSLSGKNLEVAAVGAGAFVLGILGTMMLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWH6</accession>
    <name>A0A9P6JWH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_755050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWH6"/>
    <dbReference type="OrthoDB" id="5511684at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14256:SF1">
        <property type="entry name" value="GEO09626P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14256">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="82" mass="9309" checksum="641DDD1DEA499EDC" modified="2023-09-13" version="1">MPAPLRRGFMKNWYAVEAVPIYVIIGGVVVGASWYLGRLAMGPGVVWTKTNPTPWNTVKPDENTKLMSVNQKFERSWSRDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWI6</accession>
    <name>A0A9P6JWI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_866334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWI6"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="545" mass="58865" checksum="1B980EB350ED508C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E081</accession>
    <name>A0A9P6E081_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_778848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158096">
        <property type="protein sequence ID" value="KAF9521376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E081"/>
    <dbReference type="OrthoDB" id="3143151at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33104:SF2">
        <property type="entry name" value="CXC3 LIKE CYSTEINE CLUSTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33104">
        <property type="entry name" value="SI:DKEY-29D5.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="177"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="927" mass="105241" checksum="96A86DC15C856C65" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E090</accession>
    <name>A0A9P6E090_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_900742</name>
        <name evidence="2" type="ORF">CPB83DRAFT_900748</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158071">
        <property type="protein sequence ID" value="KAF9521421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MU158069">
        <property type="protein sequence ID" value="KAF9521426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E090"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="405" mass="43917" checksum="A197B2CDD4C5B36E" modified="2023-09-13" version="1">MTKRKASDSIDNVGEPGDAATSGPSSLFSVSKKKKTLLPDELIDTTLKKIASSNGPVAKTVQQMLARAVVAGDDIMKETTGGMKPKISKKAKGKAKTINSNEVPNNVVDSVGMIIHGLAINPAFHAHLAAGLPDDGSLSIWLPFFQSQRELNAQNTAMTDQDLLKPLDSDNAITSLMTHSQLTELLQGYFPSVFDNLDRLALGEPARKHTPYVLCSKIPKGGYQPLQNPYPDGKAIAKLFSKGGSNVECKVLFGKCCRQPLSDDVNPDYVEGQLKMVHGSPEPTQLPTPPIIPTIPDPLTNDDEIKILEALCPSQLRPSSSSESRVLRPRSTIQHCWYYKSKDKDKYEVVAGLFGGTTPTSVTAVGTQSPSPMEAIESQLSQSLSFVLEDKPNPWEEIAAKEYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4M2</accession>
    <name>A0A9P6E4M2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157947">
        <property type="protein sequence ID" value="KAF9522405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4M2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="8485" checksum="56297CD9473C4672" modified="2023-09-13" version="1">MYQRQSLVAEADADEELQPPPAPPTPSPTIFGCNTSIGDEFVFDPNFNFNLALYLRTFCRSSPSPSLRTWTGHSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E546</accession>
    <name>A0A9P6E546_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_864019</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E546"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="516" mass="59083" checksum="F7564FC20157C7D0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5I8</accession>
    <name>A0A9P6E5I8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5I8"/>
    <dbReference type="OrthoDB" id="3227921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13606" checksum="29730DBE93DD3F46" modified="2023-09-13" version="1">MFIQIFWCQDRFQRLKTSARSGHVMGNTGDPGDNQTPVILSSIKTIAAEIGMVGGLWSFFNGLFVVVFGTSIMRIFFGLKLLSVFGLAHESQKSKLRDACHEEYLAFNRISQPCLQIEASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5N0</accession>
    <name>A0A9P6E5N0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5N0"/>
    <dbReference type="OrthoDB" id="3219649at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040139109" evidence="1">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="15637" checksum="77F71F04272D88CB" modified="2023-09-13" version="1">MKAAILLCAIVTSATASLVPKSGSPLTQAQAQSRLQAAGIYASSSGGCTAKSNPTCTSYDGILSGTVDGAITLKGACGCAITITGGTETGHAAGTYSHANGYKVDIAKDTGINNYVHSAFTQIANRGDGYPQWQSAAGNIYCDEGTHWDVTYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E682</accession>
    <name>A0A9P6E682_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_744060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E682"/>
    <dbReference type="OrthoDB" id="19861at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="29316" checksum="9E02877EF28E33E5" modified="2023-09-13" version="1" fragment="single">EIHKAAWGRRWPYQRRAIITNKGCGLDSDESDKHRGDKSDSYYSREVKPTHWEYTCLGGIEKLTKALTFRTRLQPNLIIRDDYEVIQLALERDLKYLQSTSKNSAAYVVTGNSEIGLTGFVLYLLLYRLERRLPTAIQVCAEYYFIFDDRGVAKLGAYQTSERLTAGTWALCDGGKEASQPCHAFQPGIVTILQVTSARMDKWKTWSNQLFAKLYVLDVPRAIEVAAITKENGFKPTDAITISKKWGTVPRTIFYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6X6</accession>
    <name>A0A9P6E6X6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_821288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6X6"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF2">
        <property type="entry name" value="TRP C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="663" mass="72585" checksum="67152BB2A8C9145B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E774</accession>
    <name>A0A9P6E774_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_862292</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E774"/>
    <dbReference type="OrthoDB" id="270728at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23948">
        <property type="entry name" value="FAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="14">
        <location>
            <begin position="176"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="282"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9523792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="319" mass="34730" checksum="76BCACF06E2D7505" modified="2023-09-13" version="1">MWDPARIAKEVYDLAAVGPSDPLSPLVKEALDVIDSCLDDHGACNVSFSFNGGKDCTVLLHLYAGALARRRLPSKSRSSPSPFTMPPIHALYIPVPSPFIALEEFIENSTREYNLDLFSCRTSNPAVESVATPAATASPPPMNGSAPKDYLTTKVINAAASRQDAPRAVGKAKGGEGMRQALEMYTERFPNITAILIGTRRGDPHGAKLSHRNPTDAGWPVFERVNPIINWTYTDVWSFLRRLEVPYCSLYDEGYTSLGSTFNTFPNPALLLEPSIESVANGAPSKPRYRHAHELQDGSLERCGRGNAVSQPSSQLQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7D5</accession>
    <name>A0A9P6E7D5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_650818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7D5"/>
    <dbReference type="OrthoDB" id="2631350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="29413" checksum="E442B0B7CB420BF6" modified="2023-09-13" version="1">MHNALAIPEIIHEIIDYLIPLGWEGSLTRERINFDNWTTLDRKHLLSLALTCRLLRGPALEALWIEVPTLIPLLKLLSNFSPQGSPNKYGFIDGPISSDDLKRFNTYASRIRLCSSLLARVESSAFLKILEANNTTFLLPKLYRLPISPIQWQDGLSFFVNPNLQSVDIYSLLPAATHASITLDSILTLQRKVQLVDISVTGDFTGIIETPFHAARKLLLGSPILIRSSASFFIWRFSVRHWIPNPRLSNNLVESRTTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7H5</accession>
    <name>A0A9P6E7H5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_798670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7H5"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="539" mass="60804" checksum="6FCD227258E423DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E991</accession>
    <name>A0A9P6E991_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_909691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E991"/>
    <dbReference type="OrthoDB" id="3341843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="7"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="35340" checksum="3740EDEA412E057F" modified="2023-09-13" version="1">MNEPKSYAVLAALVLVVYDYLLTFSDEVELVWQGRFTFGTVLFALCRYLPFIDIPVSIPLYMYANGITAAGCHNLFVASVSCQYVGIAVAQTILILRTFALWQRNIYIVIGLGVSFLTSTLFALYTTVVFMVGTTAIKPSGMPCTVDHVGEGLMAGFITLLAIETSVVVLTVVRATYHLHRSNSSWVYQMYLRGILYFFFTFAVTLLSLFCLYFAPVQLKLILMDIQRAFHSILCSRIIFLILSQRKHKSQVVSISTCREDLEETTSGLSYGVGARGIPHLSENFLGRSFVALDTLAGPDETKTYRRSRHSYTISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9C4</accession>
    <name>A0A9P6E9C4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_563510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9C4"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27284" checksum="15C9311D89381E8B" modified="2023-09-13" version="1">MLQRGSKKSTPLGTTILVALRTLDPILQYGILAHGLGAPLLGKIGLKSIVDGPPIQTGIGFIDALQLSPYRLLLLTMVTGSTIKHNFWVLYTSKEAISPSIALSVSGFNTFLNSFTTLLATSALGNGGELSRPSVIIGSTLYFVGVFTEMIAEVQRKKFKEDPRNEGKLYTEKLWSITRHINYTAYTAWRGGYALVGGGWLAGAGVSAFFLTNFIGTSIPELAGYCSKRYGEQWENYKKKTPYQIIPGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9J9</accession>
    <name>A0A9P6E9J9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_860491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9J9"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF55">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="4">
        <location>
            <begin position="346"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="734" mass="79145" checksum="C0A6B8F3F6A7C641" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9M1</accession>
    <name>A0A9P6E9M1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9M1"/>
    <dbReference type="OrthoDB" id="425925at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="27233" checksum="EB01BEF2071DC92C" modified="2023-09-13" version="1">MRFSVIRYNIKQNNNRIATQTLLRCSMFFGYCSKYMLWTVLIGIVRINALKNPLYIIHNAETSDGRQLSSYGTARASQCLPDLFGADSSHKVGLILSCRNCPSAIQTANLAAKTLALSVDSCVMDASSNWKSCLLDSIAQFEAWSEQGILLIWDENSLVNLLHKVFLMWHISLYDSDSVIYLRNGLFVSKFSQECSVDAMAEASFDSKITHPHEAFSPTPDHEASRTALSTGNTYPNERPTPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAA5</accession>
    <name>A0A9P6EAA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAA5"/>
    <dbReference type="OrthoDB" id="2877620at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="12771" checksum="A4A935839940A729" modified="2023-09-13" version="1">MFSTFTAKKEDYHKKVVHEHLKKIPAAKTAVIKNLAHSIGSVDPYIHISAALKDSAHEIIKAPRRGDPTQRDPIHHVYTNPHNPADGKKHLPKIYMKHVDKHLVKQGKKPGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAS4</accession>
    <name>A0A9P6EAS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_897041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAS4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040484888" evidence="2">
        <location>
            <begin position="21"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="18048" checksum="143D5C683C90B6AA" modified="2023-09-13" version="1">MRFGALTVSAFLAFATLVSSAPIPTTADIEARVPEPGCTKYTCTREAEAEPEPIPEPEPCTKYACTREAEAEPEPIPEPIPEPGCTKYACTREAQPEPEPIPEPEPVPEPGCTKYACTRDAEVEVEAKREPEPIPEPVPEPGCTKYACTRDAEAKREPEAATHDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAW9</accession>
    <name>A0A9P6EAW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calcium/proton exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_859187</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAW9"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000024">
        <property type="entry name" value="Calcium/proton exchanger, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="108"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="362"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="297"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="520" mass="56652" checksum="319A79A32C216021" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAX5</accession>
    <name>A0A9P6EAX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CPB83DRAFT_771734</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="5"/>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAX5"/>
    <dbReference type="OrthoDB" id="68336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 21" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="21">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040247759" description="glucan endo-1,3-beta-D-glucosidase" evidence="21">
        <location>
            <begin position="19"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF9525627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="39295" checksum="9D34A6DE342A901D" modified="2023-09-13" version="1">MGICLAVTGLIIVGVVVGVVVAGKKTSSSTRSTGSSGSTGASPNSPVQQTDPNDPSKFTKDPDLHQAFYGMAYTPVGSQLPDCGNSLAAVIQDVQIMSQLTKRIRLYGADCNQSALVLEAIKQTKVDMTVFLGNYPIATDNGAAYQRQRDVIQDAIKTYGTDHIGGVTVGNEFMLNYLNANSATDPNSAVGDQGAAILISNIQDTRDMLTSLGVTLQVGNSDAGSYFNNKVLAKVDYGLANVHPWFANVSADDSASWTANFFQEVDIAQAANISNNPKMYIAETGWPTKSSDAGNANNGPSLASEANLQTFLDNFVCQANANGTGYFFFEFCDEDWKDKQFGGVEGWWGLFSQDRKLKNVKIPNCVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBA2</accession>
    <name>A0A9P6EBA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBA2"/>
    <dbReference type="OrthoDB" id="3439489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="21207" checksum="F37825F1CDD4C2F3" modified="2023-09-13" version="1">MLVSGFKSSLDIYYAQSVYKTIRSLRLETAPLIYPSQPHIFKTQTIMTLNGRFTIKGTSAQKLIGRAYIQDESLNPKEIVLRSDNGQTPVFDLKTSGDRTEIKIDGGRTANIHNKLFAVLAPEEPTQTWKIEEISQGGGRKYIIMNDDHQGWTLSEEAPESQIDIRPIVSTKSIPPQHLPGQVWEITPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECK3</accession>
    <name>A0A9P6ECK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="4">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_857787</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HTP reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="4"/>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECK3"/>
    <dbReference type="OrthoDB" id="5432at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="13">
        <location>
            <begin position="27"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9526423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="28940" checksum="367B1E93AA0CE16B" modified="2023-09-13" version="1">MNFDLNLAPPAFLSKILLSRDGPKSRPSVTLTFAQSIDAKIGISNGTQLMLSCKETFVMTHWMRTMHDAILVGIGTVLNDDPQLNVRHLPQPAEGGKPHHLPRPVILDKKLELPPSCKLLKNFQAGCGRRPWVIYADDSSLSSQESIEFENRRKELESAGAKLIKADFVSPNGYIPIETVLKSLYFNGVQSLMVEGGAKVIESFLSSKDVDRLVITAAPVFVGAAGVGYSLTSTTPVYKVVHKENIGKDTVLVLEVTASNEHSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECV6</accession>
    <name>A0A9P6ECV6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_896076</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECV6"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23165">
        <property type="entry name" value="Prefoldin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000005">
        <property type="entry name" value="Prefoldin subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016477">
        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="15170" checksum="C17A6493755D0D80" modified="2023-09-13" version="1">MRMLEQEEEKDDVEVSWEDQQRINTFSKLNNRIRLIEEKLTILKQEKEALDDLSTELELADEDQFILYKIGETFLHMPHSRALTRLERDQATVDTKVGELAAQADACEVEMKQLKVVLYAKFGKAINLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED49</accession>
    <name>A0A9P6ED49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED49"/>
    <dbReference type="OrthoDB" id="3021279at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="302" mass="34812" checksum="CDA8A37420CEDD6D" modified="2023-09-13" version="1" fragment="single">MKEELTPILPPELEHIIFQTALSILDQKSCADIMNLLLVAKRVYQWLRPSLFRVVKAYPIREDGQYFRPWLATLDDVGKFVQHLLIYSGDIPRTKEILSKCFNAYNTCIWRNTIWMDSCEQQDAAINLLQTHSAIRRISTEAEYLGLSALLPDAYSHLTHLDILNTQVCSWEFWLPLTTLPNLSHLAITTPIKASHAKLLLIHCPKLELLISVNELRQDVLAIRDPRFVALQGYQFKEGLSDFYASVTGALGLWNFAARIACARQYGFLLAAEDRAFPRNLEWDYELTEEGNKWFKNLEKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED75</accession>
    <name>A0A9P6ED75_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_769555</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED75"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="10">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="24042" checksum="0F8903BF2E0DE290" modified="2023-09-13" version="1" fragment="single">AGLALAARLSEESTISVLVLEAGQANFNDPKIVIPGLFGQVFGNPQYDWDFSTVKQKNTGDRVHTEMRGKGLGGTSTINRCCWSKPSKADIDAFEKLGNPGWTWDDFIKYSRKSETFHLPAQEQLENYPLTYELSHRGLSGPIQTSLPPHFYRMDKLMQETLVNLGVAPNQDPYNGDILGGWIATANYDPNGWKRSDSVSAYLRPNLHRTNPNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED96</accession>
    <name>A0A9P6ED96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED96"/>
    <dbReference type="OrthoDB" id="3070253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="48632" checksum="383B05EA8EF2198E" modified="2023-09-13" version="1">MAYTESYAPPRLPQELTDHIIDHLYDDSASLRSCALVCHSWLPPSRYHLFAKVSLKATSAQAEPSYLVERCKRLHRTLVESPEIICNIRELEICEGSPLHHPHPDVQGSTTWVTTERSLTGLFKILTHVRRFDFSATSALYWTLLPPTFQKALCTLLSSPSLTYVRIHSWVFPNSAALSSLLSHCKNLKAFGISSTAVLTDNHTDSQLPPDQVNTNNDATISVTEHQEISLDVLTLDFVTFSYLEYWLLSNNSLVNIRSLRELRVANFYDASVVDKLLQAVGGSLEHFHLKPGIWDVYPFNLSRNSGLRSIRLTLDNPEKALPWAIALLSTMSATTNPYLESVGLEFYSDPKKIDGWSELDALFIQPELSGLKQVEIGLFAIPTHADFKRVQDEMDGVVAREIVRWYRLGIKSQKSSRQLTPRISRYEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDC7</accession>
    <name>A0A9P6EDC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nuclear proteasome inhibitor UBLCP1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_857024</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 16">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDC7"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090364">
        <property type="term" value="P:regulation of proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011943">
        <property type="entry name" value="HAD-SF_hydro_IIID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02245">
        <property type="entry name" value="HAD_IIID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="12">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="13">
        <location>
            <begin position="167"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9527031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="40984" checksum="CAA7508A4EDFB026" modified="2023-09-13" version="1">MSLNDGPSGGQQAGPSDLSQNSLAFQGEVNERWIDLYFTWAGKSFSFPIAESDRVYDLKVALHGLTRVPQERQKILGLVKGKVPPDQTPIAQLSLASGKKFTLIGTPEGDEIKDPSELESLPDVVNDLDIDFSENMAASNSYQHDKRNIRKVQEATKNLQINIIHPLRQRKRLLVLDIDYTILDTKPLTSGSLPPAECARPGLHEFLEAIYPYYDICIWSQTSWIWLETKLVELGMIGAQRGYEISFVLDKTCMFTVFSERDGKPWTHSVKALQIIWNHFPQFDATNTIHIDDLSRNFALNPGEGLKISAFKHAHTTEAMADRELEKLARYMVHIASIPDFTTLTHKNWKHVLKHLPPRSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDG9</accession>
    <name>A0A9P6EDG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDG9"/>
    <dbReference type="OrthoDB" id="2867594at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="207" mass="23726" checksum="845E11922C394FC2" modified="2023-09-13" version="1">MSIAVFLTCNMPEKTLDRFFDVGQDYMKEVNLHVRTEDPLTASDLIMIVTSKDPNLYPKRSPQPFQPFHSPFAGESPEQVATWFRKVSDLNSTFPMALTFIILDEQTAKDNRTCLLVSLPAHFVYQPIQSMRCDFSIVFHECDICEDGLQPSDSDYAGDFMRSRLVLTKKNKKSMEMWSFLPVINGVFVDDGKKGYGEDGEEHIQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDZ9</accession>
    <name>A0A9P6EDZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDZ9"/>
    <dbReference type="OrthoDB" id="2340858at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="90" mass="10225" checksum="2B94D9E570D95B0B" modified="2023-09-13" version="1">MGIDQPHPGDLPPAPPHLESLFTQMKAKNRDFLVRADYIRLYDYIEAEIQHDKEFPIPGRSTVIVVTGQPGIGKTTWVEYAIRHRLGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEB4</accession>
    <name>A0A9P6EEB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEB4"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="499"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="709" mass="79752" checksum="9E2F5D7EF46260BD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EED8</accession>
    <name>A0A9P6EED8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_362275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NDUFAF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EED8"/>
    <dbReference type="OrthoDB" id="20681at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05125">
        <property type="entry name" value="Mth938_2P1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034095">
        <property type="entry name" value="NDUF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="23174" checksum="FF761E94FCB08C1F" modified="2023-09-13" version="1">MSVRLFLSLSRSSLPLRRLARSTGPLNATAAQLIQPAQSQSIQFLRALHATAATRDRSFTNLLADDTPPAVQVSSISEQGIHLIDGLMIPGPCMFLEGKVFLWDVPSLDMSSRVSDERWLGWSDEKFELLDAVTPRPEMLILGTGKTLVQPPGFIRETLTMLGIQLEVMDTRNACSTYNLLSEEGRRVAAALLPLAPHLWKKNVMTGNHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEG6</accession>
    <name>A0A9P6EEG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial distribution and morphology protein 34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MDM34</name>
        <name evidence="13" type="ORF">CPB83DRAFT_907169</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MDM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEG6"/>
    <dbReference type="OrthoDB" id="17927at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21673">
        <property type="entry name" value="SMP_Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03105">
        <property type="entry name" value="Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027536">
        <property type="entry name" value="MDM34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058825">
        <property type="entry name" value="MDM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26545">
        <property type="entry name" value="Mdm34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="12">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="249"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="459"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="600"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="489"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="643"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="701"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9528011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="745" mass="81539" checksum="81DF158B54880672" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEJ7</accession>
    <name>A0A9P6EEJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_934281</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEJ7"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006130">
        <property type="entry name" value="PRK08274.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF7">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="5">
        <location>
            <begin position="25"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="57168" checksum="E8A4D7B79FC5E22A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEW6</accession>
    <name>A0A9P6EEW6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nonribosomal peptide synthetase 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_883979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEW6"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56931" checksum="F9F1B685D034A88B" modified="2023-09-13" version="1">MADAKSEKPGKVDADIQVQAVAPVYFPNDRHGDSTASSSQNSSQNSSKVDVSTTETSLELGVKEREYPWSGYKEDPLPEKEDHKIIRNLRHQLFNLYRRLFSFIFFANMAIFIAFCVYGVNAQRIGTVLVSNLFTSILMRQDYIINAWFIIFTLPPKSWPLWIRLLCARVYHIGGIHSGCGVSGTVWLILLCGQATREHVTTDKVSVATLIMAYIVLALLISIIALAHPDLRAKYHNSFEMVHRFSGWTAVGVFWAFFILLTNDYRPEGESLARTLRKSPEFWLVVVLTFSIALPWMRLRKYPVQAEVLSNHALRLHFEYVDPIPGSFSRISSNPLFEWHSFATIQIPGKKGYSAIVSNAGDWTKKKIANPPEKLWIRGVPTFGVLRIVPMFRRIVIVATGSGIAPVTPHLLAQKTNVKLLWTSPDVRETFGDKFVDMVLAASPDAVIYNTRTHGKPDMVKLAYRVYKEYNAEAVAVISNPKLTYKLIYGLTSRGVPAFAPIFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF61</accession>
    <name>A0A9P6EF61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein ZIP4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_907263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF61"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090173">
        <property type="term" value="P:regulation of synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013940">
        <property type="entry name" value="Spo22/ZIP4/TEX11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08631">
        <property type="entry name" value="SPO22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="974" mass="108508" checksum="3EB2D00578EF8FD5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFI4</accession>
    <name>A0A9P6EFI4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_751558</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFI4"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="26060" checksum="D72C5B826D1A2380" modified="2023-09-13" version="1" fragment="single">ADGEGIECQCCFAEYSFAKMVQCPEAHLFCSGCVSRFASTKLGEHNASLNCMHGSGCAQPFPVSELRRVLPTKLMELYDRVKQQKEIEQAGLEGLEECPFCEFKCVIDRSFEEEKLFRCGNEDGGCGVVSCRNCKKEDHLPKSCEEVEQDKHLDGQHAIEEAMTRALMRNCPKCKKPFIKDHGCNKMCCPNCQTFSCYVCRQIITGYDHFDQQLPNQPGPSRNSGKCLLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFZ6</accession>
    <name>A0A9P6EFZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease H-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFZ6"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="24"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29707" checksum="EEECA645ED363ADE" modified="2023-09-13" version="1">MSLLHSDQVSQASHNLNDINAHLVDNETLLNYCLRALSAPGVTQLAIDLEGVSLSRNGKLSLIQVMTDLAQNTVWVVDVTVLGNFAFEYVGQSGWSLRTILENRDTVKMLFDVRNDSDSLYNLYGITLANVYDLQLLEIAVRRSNDLNAVIVSGLSSTITQYLNPDRDWKRVKDEGNTLFKASGNQELVEIRPLDPRIIQYAVQDVTLLFQLAGKLERALGDIGKNWVKRVFKASSKRVKQALKPLPQYSNPKKAKKAKIFAPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGS5</accession>
    <name>A0A9P6EGS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DJ-1/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGS5"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040436614" evidence="1">
        <location>
            <begin position="24"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="47"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="28786" checksum="816BAF75DBBAE1AF" modified="2023-09-13" version="1">MKLLKFLTYFSFLLNAHANAAETQTTTLPKTVTSDDHSNGLPVNYGLVIFPGFTALDVFGPLDVFNSLSLNYTMNLFIIAETLDPVSTKHPMPMPLNSNFTEAVVPTHTFANPPENLDVLLVPGGVGSMLEDPALDIPIHFIKETYPSLQYLITVCTGVALVAKAGILDGLKATGNKSVWAWVIAQGPNVDWVPHARWVHTKNIWTTSGVSAGLDGTYDFVRTVYGESVGINLANSLEYSPVMDWKDDKFADLYNLTDSDTGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH16</accession>
    <name>A0A9P6EH16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_288686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH16"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="11543" checksum="E6D9E09FE1E26E2E" modified="2023-09-13" version="1">MLCAFILEEEKSTHPSRLVKLMHADEEPMAANAPFAIAFSGRSRTASAHWRTKLVARFLAFNQVHESNQGPPGLPLGRRNVCILLFFVAVRPRYASASYPVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH65</accession>
    <name>A0A9P6EH65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_893368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH65"/>
    <dbReference type="OrthoDB" id="3070967at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="330" mass="36862" checksum="98CF2460CA931255" modified="2023-09-13" version="1">MQKYNKLDDWTTVLQDFLAAQKKAKPRPLSIGTVNRHIELSKWVVHESSTGRLSAIASNFFAAAMQIAYLTSQDVEDDHLPLLCTSLESLTNVNILDLPLATQELAGTSFSTDEIKFWTDIFDSKAGESDDSTGSNGRVLQQLQLALLILPLFLFLPIKLLTKPYGKDNIVHTSIALGNKKSAILQTVERIICRALCDTATGAQAPETALAAVAECVPWMKIATCSSGDRRWFQLGELQFIRGPEHVPDLATSRAFWYTQRQAFESNNKLFDDSERSIIYCSIIPITNKEHQSRHAQALVHGIGSGRLTSRSSVVSYRQYTHYQHFTPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHP6</accession>
    <name>A0A9P6EHP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_813039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHP6"/>
    <dbReference type="OrthoDB" id="2559662at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="599" mass="68316" checksum="4532C9A6C92CB3FA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI86</accession>
    <name>A0A9P6EI86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_788665</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI86"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000002">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000010">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="94"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="207"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="13">
        <location>
            <begin position="345"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="15">
        <location>
            <begin position="618"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="860"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR003354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9530156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1215" mass="135176" checksum="187BEC4DCE918018" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI98</accession>
    <name>A0A9P6EI98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA recognition motif 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_875539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI98"/>
    <dbReference type="OrthoDB" id="417481at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Mei2-like C-terminal RNA recognition motif" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="161" mass="18838" checksum="61B51C69D01FCC54" modified="2023-09-13" version="1">MIKNIPNKMSDQDLTEYINAVCPRRVDFLYLRMDFTNGCNVGYAFVNFIRVEDLLRFAKARLGIKWNMFSSEKVLQMSYANYQGKEALVEKFKNSAIMDEREAWRPRIFYSSGPNEGLSEPFPAPTHMRRKERSSYNRGALYVPGIANEGNLHHSRQSRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ90</accession>
    <name>A0A9P6EJ90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ90"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="9674" checksum="5EDAB170A16A7F2C" modified="2023-09-13" version="1">MSNARPFFPLEIFARIMDVLAMDNQDSLGVHALLTICCCFYSLIHIFRFVVMDLWDTNNVLKSRRLSGYEPQIPQCRLQCALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJB7</accession>
    <name>A0A9P6EJB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_201565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJB7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="10015" checksum="F54CCBCE76B5684C" modified="2023-09-13" version="1">MKGRIYVPTESFRTALCNYLLDGKKSITEIIPSSCSNDLMPSAYFYLRSHAHKEQCCEIFNHLHHSPGSRLILRFLNTQRATCTVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJV3</accession>
    <name>A0A9P6EJV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Vps5 C terminal like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_875130</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJV3"/>
    <dbReference type="OrthoDB" id="271164at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07627">
        <property type="entry name" value="BAR_Vps5p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000013">
        <property type="entry name" value="Putative Sorting nexin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000022">
        <property type="entry name" value="Sorting nexin 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035803">
        <property type="entry name" value="BAR_Vps5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="293"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9530436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="674" mass="74642" checksum="76721FCC61AEFBE5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJX0</accession>
    <name>A0A9P6EJX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_189841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJX0"/>
    <dbReference type="OrthoDB" id="1911748at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13616">
        <property type="entry name" value="Rotamase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="41"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="14719" checksum="2E6C45C616A77555" modified="2023-09-13" version="1">MAKKGSTSTDSKKTDNKKNKAKAEDDSEDKQSKGKGALKTANAVNVRHILCEKHSRASEALLKIQEGQAFNKVAQEYSEDKAKNGGSLGWMTRGSMVGPFQDAAFALTPSTVDKPVISGLVKTVHGYHIIMVEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK58</accession>
    <name>A0A9P6EK58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M50B-like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK58"/>
    <dbReference type="OrthoDB" id="40823at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049500">
        <property type="entry name" value="Peptidase_M50B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979">
        <property type="entry name" value="OS02G0221600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979:SF2">
        <property type="entry name" value="PEPTIDASE M50B-LIKE-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13398">
        <property type="entry name" value="Peptidase_M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="28998" checksum="E744A35D131781E9" modified="2023-09-13" version="1">MSVSRPPIAPPTSSASAIPTHGVGALTPSSDQIVVLYVIVAMAVIIFGFWNVPVVRNFINPLKLFTIGWHELCHISAAILSGGRILKITIDPHVGGATIVEGGLPGFVLASGYIGSTLLGGAFVLAGWDTLVAKVLSFVLGVGLVLPLVLVRDKLTIVLTVCYEAMLIGFWFVDHGQALRWYCLFVGVMNILFVVWDVADDKFFHKTNDSDATQFAILYPMISAHVWATFWILFQLVCLGGFAVLGIFAFKLTQEEMDTQAAGFLPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKS6</accession>
    <name>A0A9P6EKS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_874950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the epsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKS6"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16991">
        <property type="entry name" value="ENTH_Ent1_Ent2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF110">
        <property type="entry name" value="EPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="7">
        <location>
            <begin position="14"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="358"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="405"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="512" mass="58749" checksum="B565E22D28A2587B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKS7</accession>
    <name>A0A9P6EKS7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="7">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_848459</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="7"/>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKS7"/>
    <dbReference type="OrthoDB" id="3349449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039756">
        <property type="entry name" value="Lsb6/PI4K2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="131"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="565"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="653"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="785" mass="88148" checksum="C8BBBD88BACE6F9B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKT5</accession>
    <name>A0A9P6EKT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_762770</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKT5"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000196">
        <property type="term" value="P:cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF6">
        <property type="entry name" value="MAP KINASE KINASE MKK1_SSP32-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="303" mass="34666" checksum="3E700DF2AAD59FEF" modified="2023-09-13" version="1">MVETNVIRWDDRYLQVLHRLGESSSRSTYEVKDHRSAMVYVRKTYYPRQTSCDHIKLALSTLKSSQDQAEENLNVLRCHGVYLTDGPEKGVRAVFEYCEGGSLQSIGRVIAQRGGFIGEKVAARLAEGMLQGLHYLSSLRMVHFNIQPSNVLISRSGIVKLSEPEIPGEGAAALTDRFANSVRYASPERIRGHPANIYKSDIWAMGITLLELVQNRYPYPEDLETVQLMVRIVEGHPPMLQDRTEVIWGNRMKEFFRQTLSADEVQRPIAWELLAHPWITGAMQQNVSMERWIAEVRGWPLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL37</accession>
    <name>A0A9P6EL37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_881806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL37"/>
    <dbReference type="OrthoDB" id="19092at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="779"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="515"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="616"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="731"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="298"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="526"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="750"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="878" mass="90214" checksum="CC5224F6BF26BA48" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM21</accession>
    <name>A0A9P6EM21_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase II subunit RPB9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_849307</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM21"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="8">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="10994" checksum="976A6C6AD6AA5E99" modified="2023-09-13" version="1">MVYACRICQYDESVENKCVYRNDLLTVTKEQVGVTTDLGADATLAHSNISCPQCGNDDAVFYQDQSKRKETRMILFFVCTKCNHSFMDPSLQLENPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM34</accession>
    <name>A0A9P6EM34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_848994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM34"/>
    <dbReference type="OrthoDB" id="10261027at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="267"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="659"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1036" mass="117067" checksum="07382558BA2A637E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN06</accession>
    <name>A0A9P6EN06_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_847944</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Cytoplasmic vesicle</location>
            <location evidence="13">COPI-coated vesicle membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the COPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN06"/>
    <dbReference type="OrthoDB" id="1074925at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000071">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1480:FF:000001">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000008">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032154">
        <property type="entry name" value="Coatomer_g_Cpla"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16381">
        <property type="entry name" value="Coatomer_g_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037093">
        <property type="entry name" value="Coatomer_gamma_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="15">
        <location>
            <begin position="25"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="16">
        <location>
            <begin position="666"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer subunit gamma C-terminal" evidence="17">
        <location>
            <begin position="819"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="629"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9531865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="934" mass="101938" checksum="FDC79CF58417DEA0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENB1</accession>
    <name>A0A9P6ENB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metalloenzyme, LuxS/M16 peptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_848189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENB1"/>
    <dbReference type="OrthoDB" id="4953at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000015">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000031">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF16">
        <property type="entry name" value="METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="2">
        <location>
            <begin position="120"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="3">
        <location>
            <begin position="259"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1110" mass="123708" checksum="4A8520D50ACA3128" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENN0</accession>
    <name>A0A9P6ENN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_805989</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENN0"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="9">
        <location>
            <begin position="57"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="397"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="470"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9533126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="571" mass="60785" checksum="4019AC087E760C7D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENN2</accession>
    <name>A0A9P6ENN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_785473</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENN2"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="20"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="460" mass="49508" checksum="3F3F1263D7FCFDC2" modified="2023-09-13" version="1">MLGSSGAANGTSFTTYGWLACFWGLITSFQHGYHVSVLNQIQAVLICEDLGNNTNTVPWAHKPSTCISMSDLEFSFVTSVLAIGGLCGSMVANLVIDSRGRRGTHWLCAVFGGVGNVFMGLGGSIFALSFGRFLIGFASGLGLCVGPIYMAEIVPSGNRGISVLMPMSIGVGIMVTQIVGLNFATPDSWRYVFLVSLSLSAFQAITAFGIVESPAFLLTQNRLEEQKTSAHRLWGGPYVALSPEEPDLNEPQTLDENQLETSSLLEVFKRTELRIPLLVVCLAMLSQQISGINAVLFYSNNILSKTLPDLGPYVSVVITMVNVMMSIPSIFLLDRLGRRKIFILSTFVAVCSVILIGYGLNSNSPKLASVAIVTFIMAFAFGLGPIPFVILPEVSPRHAVSALSSIALSTNWIVGFVVGLVFIPFQYLLSGGDELKEGRIFYLFAGLLSLAVLSLSRLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP76</accession>
    <name>A0A9P6EP76_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Monopolin complex subunit Csm1/Pcs1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP76"/>
    <dbReference type="OrthoDB" id="3216420at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034506">
        <property type="term" value="C:chromosome, centromeric core domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033551">
        <property type="term" value="C:monopolin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990644">
        <property type="term" value="F:microtubule site clamp"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045144">
        <property type="term" value="P:meiotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23787">
        <property type="entry name" value="RWD_CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040349">
        <property type="entry name" value="Csm1/Pcs1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28006">
        <property type="entry name" value="MONOPOLIN COMPLEX SUBUNIT CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28006:SF1">
        <property type="entry name" value="MONOPOLIN COMPLEX SUBUNIT CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="529" mass="59174" checksum="6330BC30779F0029" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPK9</accession>
    <name>A0A9P6EPK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="10">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_890186</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="10"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPK9"/>
    <dbReference type="OrthoDB" id="2525337at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF18">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 10" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040279671" description="AA9 family lytic polysaccharide monooxygenase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="13">
        <location>
            <begin position="276"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="244"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9533055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="312" mass="32395" checksum="A6F0BEF25BD0D2D9" modified="2023-09-13" version="1">MKFARSIASAVLFAASASAHTIFQEFYVNGVSAGHQVGIRVPSYDGPITDVNSNDVICNGGINPYLAPVSKTVIDVPAGAQVTAEWHHTLTSANTGDAADPIDPSHKGPVIAYLAQIPDATQTSVTGLKWFKIYQDGLDSGGKWGIERLISNKGKVSFKVPSCIATGQYLLRVELIALHAAGSYPGAQLYMECAQIKISGGGNTSPATVSFPGAYKGSDPGITINIYQTLKSYTIPGPSVFACDGSSSPTPSTTPDPIPSSTPAAPPPTSTTPTAGTVAQYGQCGGKTYTGPTTCVAPYTCKVSSEYYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ77</accession>
    <name>A0A9P6EQ77_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ77"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="755" mass="86863" checksum="1DA83297EE6F5918" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ80</accession>
    <name>A0A9P6EQ80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_757968</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ80"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14131">
        <property type="entry name" value="PKc_Mps1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000224">
        <property type="entry name" value="serine/threonine-protein kinase mph1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027084">
        <property type="entry name" value="Mps1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="39915" checksum="3D7512835865E359" modified="2023-09-13" version="1">MIGKGGSSRVFRVLNHANELFAIKRVSLDKTDAETMSGYMNEIALLKRLEGNSRIIRLIDSEVKPGPGGSKGHLLLVMECGEIDLARLLQEQMKEPVNMVWVAYYWQQMLQAVHVIHEEKIVHSDLKPANFVLVRGQLKLIDFGIANAIANDTTNIQRDHQIGTVNYMSPEAIELPDGMRRLKVGRPSDVWSLGCILYQMVYGYPPFQHLSVYQKMKAIPDLTHIIDFPDYATPMMPAPRSSTGGGPVEPPKKLDHLKQRVRKDVIMSMKSCLCRGPKERATIPELLSHSWLGFTEPAAPPAKELLKENEAIINPYYMHQLLEYGIKLASEGSLDAQALLKDAERLVQELKSIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQG5</accession>
    <name>A0A9P6EQG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_845111</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQG5"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="222"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="7">
        <location>
            <begin position="678"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="5">
        <location>
            <begin position="830"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="493"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="630"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1067"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="497"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="555"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="577"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="639"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1067"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1089" mass="123691" checksum="D89D98C92E8BCCAD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQK1</accession>
    <name>A0A9P6EQK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_843903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQK1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="7239" checksum="5CB3697FE5DA3C56" modified="2023-09-13" version="1">MTFQSVTNEIAAALLDVERKIEEARRALEKLLDKKEQLASTLNDYRDPVASPRPLTQRGAWFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER27</accession>
    <name>A0A9P6ER27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_903106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER27"/>
    <dbReference type="OrthoDB" id="3071397at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="38169" checksum="BA0CB56342A19F82" modified="2023-09-13" version="1">MNLCLGNPPRPPRNIAPAFVWRQSHSEEIAAQVNQRALAEGRSRKSFAPLREKVVKEMYAALPQEEKEKWSAKAKEQHEEDLTKWNKELKRPPSEELNDRQSSIKVLPDFLQFLVEAVGERTGWQASIIAGGPEPASGGRLNICAFWLNQHGKNSPLLEDQPKRPEGWEDSAEIFGEFLRKCYSPDECRSQAFPVNQQFTHLGNLNTSDANETQAIQVATLSSAAMAERSGSPISSTRSGSLTPRPSTPQVATNQDSEMTSDLLDRTKISTAGSSSSAGSSSMNSTADAEGYRVIQMRVTNEYLNQGANVEAPLFQSEVSRGKRRADEAQLGDNSNPSKRHIQSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER57</accession>
    <name>A0A9P6ER57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER57"/>
    <dbReference type="OrthoDB" id="7690434at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="726" mass="78230" checksum="C65C0BD6197C6A51" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERD6</accession>
    <name>A0A9P6ERD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_757128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERD6"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041385">
        <property type="entry name" value="SH3_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040992">
        <property type="entry name" value="XRN1_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047007">
        <property type="entry name" value="XRN1_D1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041106">
        <property type="entry name" value="XRN1_D2_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047008">
        <property type="entry name" value="XRN1_SH3_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18129">
        <property type="entry name" value="SH3_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18332">
        <property type="entry name" value="XRN1_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18334">
        <property type="entry name" value="XRN1_D2_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-3' exoribonuclease 1 D1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease Xrn1 D2/D3" evidence="4">
        <location>
            <begin position="152"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exoribonuclease 1 SH3-like" evidence="2">
        <location>
            <begin position="396"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="620" mass="67899" checksum="E4AF519B692C16B9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERK4</accession>
    <name>A0A9P6ERK4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_412148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERK4"/>
    <dbReference type="OrthoDB" id="3025570at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="18683" checksum="F109208C5DF1360A" modified="2023-09-13" version="1">MDNVHSTSASENSTPESAVGILDKYYSTVKPLRQYLDDVFKLSSGNVSRLVNLSRNGDKDVFLDLLTTCYVGVKQTPRLSLRVYPAALEMHEVIDQAQSRVFRSKRGQNVITSGYRLAQHSDDMGKAGMARSGITNFFVNTIINVFYGIEWRTLLQRRRCDDPSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERV3</accession>
    <name>A0A9P6ERV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_902890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERV3"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="3">
        <location>
            <begin position="299"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="630"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="630"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="672"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="684" mass="72671" checksum="F09494F51D3028C9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES23</accession>
    <name>A0A9P6ES23_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_843407</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES23"/>
    <dbReference type="OrthoDB" id="445566at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005588">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="120" mass="13321" checksum="01382D48C566D59C" modified="2023-09-13" version="1">MAPRAAQIQPTASSAVETLWKAYNDGTPNRLKFIDSFLFFLMLSGIVQFVYCVLVSSFPYNAFLAGFGSTVGQFVLTASLRSQVNPDNKDEFKEVSPERAFADFALGSIVLHFFVYNFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES40</accession>
    <name>A0A9P6ES40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Streptomycin biosynthesis protein StrI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_866421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES40"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF12">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="48"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="196"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="53955" checksum="1D51A0E4C75DE5D5" modified="2023-09-13" version="1">MSSLLNFSSSKLWKRSPKMKNSSTVLVDSAEAKYQGTQRADNPGSPVTIVVVGCGQRGKSYAKYAQHCPGRLKVVAIAEPRPKTRQYFAALHNVDKTLVFNTWQELLVASKETINTVGKPLADAVLIAVQDHQHAEVTKAFAEQGYHILCEKPMATSVQDCVEMERAVTKSGKIFGMGHVMRYSPYTQELTDIVRSGVLGELINVVQIEPVGYFHFAHSYVRGNWNNEANSSFSLMTKCCHDIDLLCHWFAPAVPVKVSSFGSLRHFRKDGKPKAAGTSTRCLDCPAERDCAYSAKKIYLSPVTYGNTGWPVETIVDGTPDIENVTHALDNGPYGLCVYESENDVCDNQVVNIEFSNGTTASFTMVAFTSAICERETRMYFSNGEIIGNMSTFTMTNFKTRVTKTHRPVNEGGGHGGGDMGLIRSFVEAVRTRQQNVLGTDAQDVLKSHLTVFAAEKSRREGRVVDCVEFEKEARKEAAEKEKDPFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES84</accession>
    <name>A0A9P6ES84_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_742404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES84"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070139">
        <property type="term" value="F:SUMO-specific endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051947">
        <property type="entry name" value="Sentrin-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896:SF3">
        <property type="entry name" value="FI06413P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="13"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="71" mass="8184" checksum="41F05C6F98AC7931" modified="2023-09-13" version="1" fragment="single">RILSYPQGQPGAVNVTAGDLNRLEPGEFLNDTLIEFGLKYWLHQLEIMNPALASQVHVFNSFFYKKFNQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESE5</accession>
    <name>A0A9P6ESE5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_419793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESE5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="22780" checksum="A02139D2E9667A5F" modified="2023-09-13" version="1">MARKSGSVSSSSSVSPASTNVSLPYTSSSFQHPLDIKPQHYHLEQYPNSWSSSSSVTTDEISSYRSSPMAFDYSPDNTTPSTPSPNSDYQSYDLPMNHQVSPYSESTQLYQESVPPVTQPNQVYKPFHNHGHADTPFQGHQFSHFPAVQVHSGNDSADQFGIFEGQATSVDATSAITGLSWDAMSSTQDVKPLSGGFRAPLANNTYSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESF6</accession>
    <name>A0A9P6ESF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_902697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESF6"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="105"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="763" mass="87549" checksum="094F9012851733B0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESG4</accession>
    <name>A0A9P6ESG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESG4"/>
    <dbReference type="OrthoDB" id="2960209at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="181" mass="21119" checksum="2666EA6991D471E6" modified="2023-09-13" version="1">MSFPSRYSLTSRRHKRWHPFGKRLGWFIFGATITAWLIKRKEMHDRELKWGHCRRPQLQYYLPDTPDESNAHRCRHLLKEISRAINDCNSVWCDAPEHTPHSASFPKRKPPASAWVDAEEDSLDKITATATEYMSELTEASLDAVIETVRAFKVKLLCRHGRNENIHPEAKTDQPTETKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESR0</accession>
    <name>A0A9P6ESR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol/phosphatidylinositol phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_841800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESR0"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="572"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="121"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="668" mass="76160" checksum="B1800C9AF66772EA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUR5</accession>
    <name>A0A9P6EUR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_841584</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUR5"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="55"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="106"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="110"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="550"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="614"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="587"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="659"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="689" mass="76676" checksum="015CCE7D03BE5783" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI26</accession>
    <name>A0A9P6JI26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_900391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="MU158000">
        <property type="protein sequence ID" value="KAF9521704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI26"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="344"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9521704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="46165" checksum="BFAED169C3D482A7" modified="2023-09-13" version="1">MPIFMNFITTSLPMSQFWSQTLKPQDSFKILSPDTIHVQNATLGHSLTNTGGSARTSLHLTYVTQEKEEKETYVCSLTPGKIEHVSLNLVLTGDTVFHLKVIGRNSIYLSGTLNLPHAQQQPSQVDVAAQTEPLAATHTRPDSEDRELATIRSTEEGLHAVGDQNRLPFPELPSPVKDTYDPSTATLPSSVLVNTHILPLELGEASTNTGRVAESKASPRKRNRRSSSPKKQLTVVASDATSNIVAIGATTTSPDKPAPSKRIRKSTAKAAQLATNSQAPTNSTPISRETNVPAAPSSPAKFPSLTTFNAAVDASVPKGNAHGQYVTSRDVKLGDKSGACAVFGREVSLIFRVKAGESVVFSDFSKNPHRFCVGNQDLVPGLSEGVTGMRKGGQRVIRVPASHSGGELAFIPRGLTVNSELTIECQLVDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJQ2</accession>
    <name>A0A9P6JJQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_862804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJQ2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="11984" checksum="CF2E419B751330DB" modified="2023-09-13" version="1">MSGLSLTDISNSPFKRDTVPFSDDPASSNSPNSPNAPNAPNYQDFEFTKSYPKPGPDIGAIVGPIIGVMLLVIILGWACRLKISRGVRSSASPGSKVPGKFVSWKLGVGYCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK41</accession>
    <name>A0A9P6JK41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_862809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK41"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="21"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="14630" checksum="15EFC4A746829C55" modified="2023-09-13" version="1">MHPIPASDTQHLVTQAYAGHPTYICSHCSAVIALQDEMISKAFSGREGRGYLMNAATNVKLGRKEDRSLMTGVHTVADVFCMGCNDRLGWFYHKAADPSQKYKESKYLLEREKLVKENNWELDKPSPSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL19</accession>
    <name>A0A9P6JL19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_594384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL19"/>
    <dbReference type="OrthoDB" id="2757916at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="33246" checksum="05B4B7BFC2938F30" modified="2023-09-13" version="1">MPFSVDDTIRATSPKSNAYRTGNQPSPVPCRHRDGTRSRSPIKGLFTSRSSLAESSTAVQFTVLEADITDASDDSGVEDDAVYISHFSVASRNARLRSSGPPGLTPPYPTSISPSPTPKSKNRSFNFMFAKDFSGTLKTNPSSPISNVQDESCTVVPLPHRNAPSPPSQPPCVAVSIPSVTISAPSAGLDAPTVRASSSRTPATSATIAPSTIKSKHNQPRFTARTRLHSLLKDVRHGRISSSIPSSPVPRPSRTSLHPPPLELSGSPESRDLTDLDLFTEDDDETPRPSPIAEHYCKIPTVPMVRSFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLJ6</accession>
    <name>A0A9P6JLJ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_897469</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLJ6"/>
    <dbReference type="OrthoDB" id="158672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="8">
        <location>
            <begin position="89"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="831" mass="91379" checksum="DA10735690413ECC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLK5</accession>
    <name>A0A9P6JLK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_595015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLK5"/>
    <dbReference type="OrthoDB" id="3036455at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="283" mass="30966" checksum="C5F1821EB25DE46E" modified="2023-09-13" version="1">MHHISSNRSVKNLSVEATEEQKAQLPSTLSLPQITFQLQSSSPPHQSISITRQSSSSNLPDSKNRISVSNASLKILWLLLDNVLLLQMGSAYLIRFHEFALAADGGKDLPSIDDWRKEQQAEWNRLSTTLGLLAAMHAAILAISPQPPNLAYAFWLGGGTLSVCGLFIVQYFPIKAFSMTDEDIGFIVTNGNEIFNTTLLAAAIASPVIICLWAAVLFIAGMIDYIIESDLGGVKYRVFAAIPVGFGIGAVVMTMALGEIIDRRMKQKYYPDGLPHTDRNKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMG3</accession>
    <name>A0A9P6JMG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMG3"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF105">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="527" mass="59458" checksum="1E65BE98233F367C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNF4</accession>
    <name>A0A9P6JNF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_738094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNF4"/>
    <dbReference type="OrthoDB" id="2970937at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="10406" checksum="A8720CD1A1099673" modified="2023-09-13" version="1" fragment="single">IPVRFLIASRPEARIKNTFHLDPLFEGVSIRSMDLDQDQNARQSVERFLLDEFAKIRKAHPYLDHSWPSDDIIQTLVDKSSPQFIQVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNF6</accession>
    <name>A0A9P6JNF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endo-beta-1,3-galactanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_816712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNF6"/>
    <dbReference type="OrthoDB" id="4524534at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040150374" evidence="1">
        <location>
            <begin position="28"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="25"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="28562" checksum="E33F65D7DF91FC10" modified="2023-09-13" version="1">MMFFRHTHGLAFAGVLSALATFPRVQADTTVIPSTSFSSYSTFESYWAYLYPWGSDHNGSARMKGSSSDHSNIVIASNTLSLIATPTSNPSPPTSSSNPHPAIHYASGAVHAKSQITVTQANSYTISGEFSASTAKGTWPAFWLTAVNGWPPEADIGEWKGTTNNWFNTFNTSSIVRSDLVTWPSDLSFHSLKAVLTAQPNNVDVKLQFYMDNTLRATQYGQGFVGKPMWLIINLQMEGSSGSPGPTGTTTYKARNVVVTRTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP81</accession>
    <name>A0A9P6JP81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_814141</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP81"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000957">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3L, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="359"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="561"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="872" mass="96669" checksum="A6A32EC8EFA86A5F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPN3</accession>
    <name>A0A9P6JPN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_855133</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPN3"/>
    <dbReference type="OrthoDB" id="2020758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="80"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="15"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="329"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="471"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="600"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="753"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="802"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="871"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="957"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="634"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="755"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="808"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="829"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="871"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="957"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9527988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="999" mass="107692" checksum="DBF859E8EE0723AC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPT5</accession>
    <name>A0A9P6JPT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance-associated ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_855418</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="648"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1052"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1093"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1195"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1278"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1305"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="334"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="764"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1054"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1370"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="426"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="427"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9527915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1621" mass="180091" checksum="AD523401AFC80294" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQG2</accession>
    <name>A0A9P6JQG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome production factor 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ribosome biogenesis protein RPF2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_875910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
            <location evidence="1 4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RPF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQG2"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039770">
        <property type="entry name" value="Rpf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728">
        <property type="entry name" value="BRIX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728:SF0">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="28"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="37807" checksum="504DFB3099FCE529" modified="2023-09-13" version="1">MLRAVKAKNARSKRVLDARLPKEVEDARTTIFVKGTHTGDVLNSVMKELMALKRPHAIAFNKKNAILPFDTSSTSHQSLEFWAGKNDASMFVVGQSTKKRPHGLSFVRMYDGRVLDMLEVGIENWAGMSSFKTPKSTPGHKPLMHFASELFDTHPRFVQLKSMLVDFFNGEEIDSICLPGIEHVISVSCAPTPSTLNTATLPTSGVTQDDTASLPKVHVRTYTIKLLASGTRIPRVELVPMGPSLDLVMRRHQPADSELWKQAMKRPKLKKTEVERGLGKKKKNLEVDDMGDLRGRVHIAKQDLKKLQTRKMKGLKGGDENQDEDMEDSREVKRQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQZ2</accession>
    <name>A0A9P6JQZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQZ2"/>
    <dbReference type="OrthoDB" id="2922289at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40788:SF1">
        <property type="entry name" value="IPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="602"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="879" mass="97243" checksum="A22E9411B3620CE8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRU4</accession>
    <name>A0A9P6JRU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_893053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRU4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30139" checksum="DD76BBD1143EF4F5" modified="2023-09-13" version="1">MSLPEWKSQIFPGKIRAILSWPSSGLLVVASREQVMLWNLQTKTQVYVLDLAFNLLDIKIAQLQAQSSAFGLYVLGSNGLVFIYALQNDTITCVGKIRLLRTNEDDVAYGSLSVEGNFIASTFGKNVVVRNSDAKDKRVITAKHGYIFQGIHSRKKITHLLFLSPNRLMILSYEAGLLVTFDLKLEMRCQVLRLPFHPSSATFSRKNDVIVFHDPFGGTYFYNATELKPVNSILGGTTTTATLALPAYLTFTEDEQAVGIASNNGKFCFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRZ7</accession>
    <name>A0A9P6JRZ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_834608</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRZ7"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000050">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF35">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="17"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="480" mass="52814" checksum="93E716F3C90952B8" modified="2023-09-13" version="1">MATSSTPDFNKVLYRPLAEIDPEVKNIIDKETWRQFTGLELIASENLTSQATMEANGSILTNKYSEGLPNARYYGGNEYIDELEELCRKRALVAFNLDPAKWGVNVQPYSGSTANFAALTALIQPQDRLMGLGLPDGGHLTHGYYTQKKKMTASSIYFQSFPYAITKDSNLIDYDALSSQAKIFKPKLIICGASAYPRDWDYAKLKEITIRDGAFLMCDMAHTSGLVAAQELNSPFDHCDVVTTTTHKTLRGPRAGLIFFRKDLSNSPDLEKRVNEAVFPACQGGPHNNTIAAVATALQQVAQPEFKAYAKQVVANARALAETLIGHGYKLQTNGTDNHLVLWDLRPIGLTGSKVEKICDLMGITINKNAVSGDASAQVPGGIRLGTSALTSRDMKEADIKLVGDFLHRAVQLSLLLQKEAGTKMLKDFVRVASKQEEGKVGHQQVKQLRDEVREFAIKWPLPGVDVANLQKPDGLHEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS06</accession>
    <name>A0A9P6JS06_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_725405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS06"/>
    <dbReference type="OrthoDB" id="3045137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="163" mass="18279" checksum="1CDEC7E61240401F" modified="2023-09-13" version="1" fragment="single">ALVDAKERFNPPNCAPETRDAILQDIKRWSNSGRWSPSFFWLTGSPGSGKSAICQALAELCKQDGTLLANFFFSRVAGSAGRSNGDRLLPTLIYQTMQNLPEVRQSIEYAIRSNRSILTSTRAALIQTLFCAPLSQFSVRRFFREWFGTPIRLVIIDGLDECQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSY6</accession>
    <name>A0A9P6JSY6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_624383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSY6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="621" mass="67709" checksum="63B987BB88A77DD6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTV1</accession>
    <name>A0A9P6JTV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_881080</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTV1"/>
    <dbReference type="OrthoDB" id="6703404at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="118"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="220"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="324" mass="34956" checksum="AC57D9E3029FC0A7" modified="2023-09-13" version="1">MSSTSSSSKTSQPITALEGFGCGAVAACIAVTVSNPAEVAKTRLQLQGELAKGGVKKVYSSAADVLVKTWRYEGIRGLQRGLPPAYAYQFLLNGSRLGFYEPFRRNINRFFGYEPQQQLPFTSVAAGATSGAVGAALGNPLFLIKARMQAYSPALPVGTQHNYKSSLDALARIFKAEGLRGLVRGIDAAILRTSMGSSVQLPSYNFTKNLIVSNDILPANSTWTFLLSSSVSGACVCLVMQPADTALTRVYNQPTIVGPDGKIRGALYRNPIDCLWKTFKAEGVKGLYKGSTAHFMRIAPHTIITLTMNDIIINLYKSAKDRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU36</accession>
    <name>A0A9P6JU36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_844525</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU36"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="134"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="32621" checksum="A272582033D22706" modified="2023-09-13" version="1">MASVAATEEPIGQRNKTDGTSENPDLCMRLKSQRAMGLKSQLKAIQDEMKKQTEIVEAELSAMEQEYNDLSNASRQRELGLNTKLTELQARLVQSMEETMTKQTELNKLQERYETLFASHAKCASNAKTLDFRVSLLSRQKASAERDLENAKSEHFSFENFIIAKYQGEKEDLQRKLKQEKGRVLELEKSEEARTRKIDAIEALLYNYLNQPKHPVLQSGEASRSQQTSVSTTPMESRRFRTKQTARKTTGGQPPQKQLAGREPSRTQSTMKMKSSGQTTKKRRLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUA8</accession>
    <name>A0A9P6JUA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_758580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="3"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUA8"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000006">
        <property type="entry name" value="non-canonical poly(A) RNA polymerase PAPD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000003">
        <property type="entry name" value="non-canonical poly(A) RNA polymerase PAPD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="9">
        <location>
            <begin position="218"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="8">
        <location>
            <begin position="420"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="129"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="576"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="732" mass="82181" checksum="5D00A050E367D4DF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUU5</accession>
    <name>A0A9P6JUU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA replication complex GINS protein PSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_802814</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GINS2/PSF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUU5"/>
    <dbReference type="OrthoDB" id="1938138at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21694">
        <property type="entry name" value="GINS_B_Psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1020:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.50:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056784">
        <property type="entry name" value="PSF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25005">
        <property type="entry name" value="PSF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028998">
        <property type="entry name" value="GINS_Psf2_subgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF2 N-terminal" evidence="9">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="8">
        <location>
            <begin position="75"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR028998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9534692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="21032" checksum="D4E927BEB3BE71D4" modified="2023-09-13" version="1">MALPQSLRVSVTPPELELVASQQLVEIVPLIAMEKTAFISGAYGPLRPPNKAKVPLWMAVNLKLKKKCHIVAPEWLNVEFLQERVNLETTQPTFSHLPLRFAEIAKVILDVASNDLDNPDKIRSLLKDLREARQAKSRDGLKELDHSELSLPNLCSMEINEIRPYFVQAMNVLTQLVRNPVPDPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVR9</accession>
    <name>A0A9P6JVR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Galactose-binding domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_782236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PITHD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVR9"/>
    <dbReference type="OrthoDB" id="2635at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045099">
        <property type="entry name" value="PITH1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175">
        <property type="entry name" value="AD039 HT014 THIOREDOXIN FAMILY TRP26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175:SF1">
        <property type="entry name" value="PITH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="3">
        <location>
            <begin position="20"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="23521" checksum="34F29276C30AB398" modified="2023-09-13" version="1">MPHEHNDHCGHESHEHDHNHDSTELGFQDNLYLHIDRQNAVTLNSEGKASDILKPWHERLDENKYIESDADDQLIIRIPFTGSVRLRALLLKSGPGDQTPSKIALFANEPNLDFEDVSDRKPTQEFNVPQGREVGEYAVKTARFSNISGVTLFIPSSQGADTSRIYYLGFLGSWTAAKQQPIITVYEAQANLADHEKIQGMDGTWSAPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX41</accession>
    <name>A0A9P6JX41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Diaminopimelate epimerase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX41"/>
    <dbReference type="OrthoDB" id="75169at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF17">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="33190" checksum="67161C1CD5AA2728" modified="2023-09-13" version="1">MAVVSAPFALVTAFSTNITGGNPAAVVLHDTSRPLHELAALARTLNQPILAVVSSSPLPSDEPHVQIREIRYFASKNGDEQRICGHGMLATASVIFSLSEFASTGLRTIIFKNPIYGLSFRAMATKLDDGFIEISLPAPSLGEVDENKKMAIRSHVNKAFGREVKIKDIKTGGTLLPHYCLIVLDEKEILAGSTIHASALIETGFVIHVVTIKSPDPEYVFYSRMFAPLALIDPGEDAVCGSAHGISGPYWHEQLGIQAGTEIKAKQVSERGGHVRLIWDVAEGFVRLRGQATVLASGTVQVPFGLPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BDA5</accession>
    <name>A0A9P6BDA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158051">
        <property type="protein sequence ID" value="KAF9521475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4161428at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1440"/>
            <end position="1475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1876" mass="211289" checksum="B363F65ECA9E881C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2T7</accession>
    <name>A0A9P6E2T7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158172">
        <property type="protein sequence ID" value="KAF9521275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2T7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="274" mass="30777" checksum="AF95854AE92F8E96" modified="2023-09-13" version="1">MLRILSSIQALPAWLRCFCIPSSATIDIASFISFSPNEESITRDQLSPLAAALSRFRNSMIGSPLQFSDLDITRTSIRRLNLRGFCSSEDRPSFSLSIHGGVGVDENIEETLAEIVPTLPCSQVHSLTFRVCAEVDPECWRDVFGRMLLKSIIVDCKPADGLMEALKPLMKNGKVDLSFFSLQELFLENPDFECSTTTEEFQECLASRKTAGAALLKLTCEGAYGLTIENVERLKTVVTEVDWTPNLQPDVSPHPYWLLRGNENNYNPYDLNWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3N7</accession>
    <name>A0A9P6E3N7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Restriction of telomere capping protein 4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_900080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157971">
        <property type="protein sequence ID" value="KAF9521948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3N7"/>
    <dbReference type="OrthoDB" id="2686745at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="2">
        <location>
            <begin position="608"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="929"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="986" mass="110145" checksum="929A916A27F4432F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E462</accession>
    <name>A0A9P6E462_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIN domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_919195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E462"/>
    <dbReference type="OrthoDB" id="3005703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09906">
        <property type="entry name" value="H3TH_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037316">
        <property type="entry name" value="Yen1_H3TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="2">
        <location>
            <begin position="73"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="328" mass="36599" checksum="6BCA30BD9396912E" modified="2023-09-13" version="1">MAECTTIAIARGRHQQPPGGGLYIFWHRLMNFLQAPITLIFVFDGSGRPGIKRGHRVVDIPPYWLEAAMELIDILGWQTHQAPGEAEAELAMMIRLGLIHGMITADSDSFVYGALYVLLPSNQRIEADEYMLYDLAEVLSHAVDGMGLTRGSLVLIALLCGGDYDPSGVLSCGPAVAHALARCGFGDELLRIIESGQSQARIDNLLADWRRRMRAELESNNSGYLGSRHPAIAQAIGTNFPNPGILRLITSPLTSWSSDHNIPVFRTLALPPNIFRLTQFCLRYFYWSLDLLFRRFEGYVWEGIFLQLLYSVNAIFILISFILSNILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4R6</accession>
    <name>A0A9P6E4R6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157947">
        <property type="protein sequence ID" value="KAF9522399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4R6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="1">
        <location>
            <begin position="28"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="23878" checksum="5FF35B7D2D6516E6" modified="2023-09-13" version="1">MQDGSILSMSGPAGPEVSYLPSGIKPSNFIKIDRPGGNISGAFVIDRHMKIPDRAKGYNLYLSSVPGAGSIKVDIFSVPPAAAVTAIERKERTMINITGEKILANFHRPQIDEKSYPFHVIIGGSSQSTSTLSLPRSFKGPVRFYCTGDWVTFSPDLLANFTLFIEEKGVTEGFVGDFDFTQWEAFNQWKGDVFYWRPASTTTTMLILRYNDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5L8</accession>
    <name>A0A9P6E5L8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_776262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5L8"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF32">
        <property type="entry name" value="ZINC FINGER PROTEIN RST2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9522959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="191" mass="20884" checksum="204D28EDD311A329" modified="2023-09-13" version="1" fragment="single">MGGHSASNGGSASKRYRPAPAKTFQCRGYGECRMVFSRSEHLARHVRKHTGERPFSCHCSKQFSRLDNLRQHAQTVHADKQDENERMMRDLTSLHATMSAANKMGSGTRVSRRGATTGGANSASSVATSGAPLSLIKQEESPPMHQRPGTSTGYEGGDMLYYENPTSSRPSASNSSFRDQSHSFREPGQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E657</accession>
    <name>A0A9P6E657_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_863137</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E657"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="30"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="413"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="698"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="791"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1112"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="503"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="584"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="736"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="760"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="804"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="818"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="851"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="896"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="961"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1115"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1186" mass="129136" checksum="98ADB8A16A00624B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E674</accession>
    <name>A0A9P6E674_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E674"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="7468" checksum="A1A465626C8F18B9" modified="2023-09-13" version="1">MKKMSIVFGFGRRIFPGRYFVQGTPFSTIATFLATCHILPGLDEDRRVVKPEPKYSSGTISIPKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6N9</accession>
    <name>A0A9P6E6N9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6N9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="42280" checksum="0407E4401DC2E1EC" modified="2023-09-13" version="1">MNTAESILYPSFYFRDMAFFLTKFVTDRFERNSSPFQDDSLSYNLIPPTLSACSSSCSSGSTDSLLITTALNNDFSSKWEERIYDVILRTLQLSEFDESVVVGTAVLLDMMRDMAINSQRRRAQGSMEDPILNLPAFPHEDYFKFFVGAYIHAYHLLSDNSEMISPQRWSEITGGMLSGEQVLEVEIDFREMLEKHMSSYEAPSYNNIVDGIETIYVQDEVTSVPPNPFISEDRYLNTKSTMFTHIRLAMTIRGQRPHVPDTVFCDDDSTVLDYSLTFSPCESEMKFRRVMLNIAKDQYEEINSASDRKAYSWIMGNTDRTDEETDSWIFSSMELGKGVSGLRRLENTYVQKVTKTFKTFGDNDWTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Y7</accession>
    <name>A0A9P6E6Y7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HHE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Y7"/>
    <dbReference type="OrthoDB" id="9983919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35585">
        <property type="entry name" value="HHE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35585:SF1">
        <property type="entry name" value="HHE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="22828" checksum="BF911A4695E2B89E" modified="2023-09-13" version="1">MASTADMGTNTETGTLLRSITNDHREIFDCYDQYVKSQGDHDAQQRWSNQLAWEVARHSVGEELVVYPLLEKHLGADGKKMADEDRAEHQEVKKLLAKLEGTSAGSAEHAAILKSVIDNLKPHIEGEEKHDFPLLERVLSSAESKEAAVKFYKTKQFAPTRAHPSAPNKPPFETLAGFMAAPLDKLKDAFSKFPTEEQREVAGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E741</accession>
    <name>A0A9P6E741_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_775083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E741"/>
    <dbReference type="OrthoDB" id="3219836at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="22548" checksum="0A2923308F4A6F79" modified="2023-09-13" version="1">MPAPDVTSYRCIETRPALGHVNLMLDTFISNAAPEDLRSIMRNLLATGPPGITPAFTNAARCCLRQTNCKVNPYLLFSKQSRDSPATPLPHLQDVLTRARSLFGAGMGFASLGLLSSIVRATIGLRWEEDGDMADFLAIIDSDITQAIQSCKEEQQSGRLVDVSSARDAKNELRSSLNDSLADSKLWGGEYAFERALLSMDYWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E763</accession>
    <name>A0A9P6E763_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_798997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E763"/>
    <dbReference type="OrthoDB" id="1918363at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="868" mass="96827" checksum="DB891D84DD6BBBEE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E767</accession>
    <name>A0A9P6E767_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E767"/>
    <dbReference type="OrthoDB" id="2150628at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051667">
        <property type="entry name" value="Archaeal_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37096:SF1">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37096">
        <property type="entry name" value="YALI0E33429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="95673" checksum="A37BD6EF0DBCFB4D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7F5</accession>
    <name>A0A9P6E7F5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_651900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7F5"/>
    <dbReference type="OrthoDB" id="5570013at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="463" mass="51676" checksum="A26A2BA6F8DB8879" modified="2023-09-13" version="1">MASHLDQKNPSGSPLPNGYTLLSYSPDDVILGRRRREPCTPKRFFKALLMAGGAFFVLSTLAHGTFFCAKRWSVHSVIPNHWDENPIPDDVALSHCASSDDWEVEDRVTDFDWKLRFPYQSTTHFDIPLAPDTLWFVTKGISSVGSLNIVTSPDQPKDKITYYVTAHYYKEEVRDLADVCIITKKDNENQEGVGIFTSRHGEPRRRRENRLSFETTIVFPESDDGSALLIKDFVADTFITRIQTSSLAEKIIFKNISLQGYLAPIKFSLRAVEGTISTSNAPIEGYFNTTGNLELITRNANIKVDIVATSVKNGSEPKVILETVNAPIEGSFHLVSAEGANGTFHVTAKTRNSPLKVKFEDAPADAILVFNAETANSPAEVALHPTFEGSFLAETSTFFQAKVLYDQDEEDPIGKERQRQVLFEGKNNGQTKQGYVFWGDQEKEKLKGRVTVKTSLSPVELQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7L9</accession>
    <name>A0A9P6E7L9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Peroxidase</fullName>
            <ecNumber evidence="18">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">GP1</name>
        <name evidence="21" type="ORF">CPB83DRAFT_861958</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="15 18">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15 18">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="18"/>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7L9"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00692">
        <property type="entry name" value="ligninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024589">
        <property type="entry name" value="Ligninase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11895">
        <property type="entry name" value="Peroxidase_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="6 15 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 18 21" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040547583" description="Peroxidase" evidence="18">
        <location>
            <begin position="23"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="20">
        <location>
            <begin position="68"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="317"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="16">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="41"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="60"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="270"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9524031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="367" mass="39542" checksum="72A1CC2D8BF829B0" modified="2023-09-13" version="1">MFAFSSYAVILLSLSRLGLCSSNSPKRAPENWGESPSDSRCSGLLPLMQALQQNVFNEKCGSMVHKALRATFHDSIAYSQSQSTGAADGSLFAFSEVELTYRANGGLREYVATMKPYAEHYGISSGDLLYFAAAVGLTNCVGGPRLDVFIGRPAAVGPSPDGMIPGPTQSVDAILARMADAGFSASELVALMASHSVAASDNIDPTIPETPIDSTPGCFDSQFYIETSLKGTTFPGTGNNAERGEVESPSKRQIRMKSDFELARDPRTSCQWQSYATDHSRMQADFKMAMTKLMTLGQNMGDLINCSDVIPQPESLKSTMKPHFSADHSIDDVDQSCPNSPFPDLPSESKDDIPGKQDGGSDDRQNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7R4</accession>
    <name>A0A9P6E7R4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SigF-like NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7R4"/>
    <dbReference type="OrthoDB" id="2344312at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057514">
        <property type="entry name" value="NTF2_SigF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393:SF1">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24840">
        <property type="entry name" value="NTF2_SigF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SigF-like NTF2-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="21679" checksum="B0B541C7D5023F28" modified="2023-09-13" version="1">MNNAWDDVSRVVQEICGAKSPEAQKMAIERYYTSDVYFKNPVCEIQSGEKSRDALVSVLQWYRILSPQVDIKIDGQAYNEQQDQHAIYLDISQTFKPFFLPISPKVSKITRRLRLRRQGNQVYICAHEDFFHTDDMIGFLLPFLIPVVSAGMRTNTFVSIMMTKMAQTFGFWRRTKESQANGQAKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E891</accession>
    <name>A0A9P6E891_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_877663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E891"/>
    <dbReference type="OrthoDB" id="3191896at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="240" mass="26281" checksum="1BE91C9F6C878A2F" modified="2023-09-13" version="1">MDDSFDPLEKIFQKVEEESERRAQKELEREEAAELHDKPPVSKAQREKERRRGSISISRFGKVDENSASPSPTPLTPTISTITSNSPFYQAQIANGSTTSVASGASAFSGEHAHSEDRNHVTQMQHIAGKQSISSRIIPRRLSRANSTSVMPSTLNQVESNVIIGVSVQEATEDSAHPKGDDPVPVERRASVQALGVPSLRSKASRSSLMGTKTTNTSWISKARGFTLKFRRKAAEKQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Z9</accession>
    <name>A0A9P6E9Z9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_871004</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Z9"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9525039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="59788" checksum="778070EACC4F038E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA38</accession>
    <name>A0A9P6EA38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Family 88 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_818971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA38"/>
    <dbReference type="OrthoDB" id="4138492at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41814:SF1">
        <property type="entry name" value="CELLULASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41814">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="48976" checksum="24AACE45AADE4E1A" modified="2023-09-13" version="1">MVNISVVSTIAAAVTDYQTFPFDPGFDIQSILKVTQSLPSHSWEYGTFAEALIEIYNPEISVFGETPFPVPSFAKNDIKALNYLQPKVVLGTGYTSLAKGDGAAGDPASMGVGAVLLGKSLPTFATAAEETVTALLKDTPRFANGAISHRADVAELWADFMYMVPPFFAYYAADKTNETLLREAVKQCGLYRDVLQSKSNDQWNGAWHHIIGPQNQDLGLWSTGNAWAAAGMTRVLATVMKLDWLQSTWKNQAADQLSLYIKQIVDAVVKAPQDGKLLRNYLNDLDQWNGGFGEISGSSLMAATIYRMAVLRPDTFGQSYIRWADEIRQTLGEKDTQGAAHVTPAGVVTPAVNPLAWKDPIPYTAGSPEGNSFAVLLYAAWRDCVLAHKCVSPAPGSSLAPPPATIPRPTTKCPNRRQQVKAKRSLTNRQRDLARRHIGRRGFHINPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAF0</accession>
    <name>A0A9P6EAF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAF0"/>
    <dbReference type="OrthoDB" id="5396786at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055105">
        <property type="term" value="F:ubiquitin-protein transferase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019516">
        <property type="entry name" value="Glomulin/ALF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013877">
        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430:SF1">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="557" mass="61814" checksum="AD3BD5D690054436" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAY1</accession>
    <name>A0A9P6EAY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_896841</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAY1"/>
    <dbReference type="OrthoDB" id="3228837at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="78"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="238"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="809" mass="93019" checksum="A73DE5260D7EEB45" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBQ3</accession>
    <name>A0A9P6EBQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_817494</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBQ3"/>
    <dbReference type="OrthoDB" id="17644at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="716" mass="80931" checksum="39838E0E0C2D2277" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBT0</accession>
    <name>A0A9P6EBT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_770842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBT0"/>
    <dbReference type="OrthoDB" id="1926212at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052346">
        <property type="entry name" value="O-mannosyl-transferase_TMTC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44227">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44227:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21778" checksum="DE29E31B7753AD49" modified="2023-09-13" version="1">MSANLERSNGRLKFTGWATSVTPQSSASDPAETEALKCLEQGTTKLEEGDLQGAKSLYQRSNEIKRSASSLFNLGVTHYHLKEYDDAISSWKESISLQPSSPDAHTNLASAYIISPVSRPDLALHHLGIACSLSPEDPEIAFNHAAVLEATGRLEEALEEYKRSQKFGVERAAVHIRNVGAKILGQKMKELDNSDKKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECH9</accession>
    <name>A0A9P6ECH9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_938026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECH9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="184" mass="20704" checksum="0674794AAA99AF4C" modified="2023-09-13" version="1">MLPVVATISIAAKNAKSQTGNCINCKSRTSFETPPSLDSRRAIVFEVNGEIKFTWVTVKQETDGEPIDEDHPNLTWEVPVGLEHYFHGNSPSHEAFHTNAVRRRTLKELIDLRINDNFQSDGSPKNLAVCRVVNEMDYGEKTWRDPLVALKKKGSWLDDKRLNPNPAAGYGLWIWAISGRLSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECW3</accession>
    <name>A0A9P6ECW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECW3"/>
    <dbReference type="OrthoDB" id="2884715at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="119" mass="13441" checksum="5ADC96BA14C60E2B" modified="2023-09-13" version="1">MVENWMAHRDIDYTSLTRLLLFSGGNCIQEGALSKANSSQTRSTLTSISTPLATRKIGNDDVSEISFGAMSLSVYYGEVPSDEERLKVTSLFFQRNYKILKKNSHFRFSTLSLKKDADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECY9</accession>
    <name>A0A9P6ECY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_769792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECY9"/>
    <dbReference type="OrthoDB" id="5106486at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="11840" checksum="38632E626F85614A" modified="2023-09-13" version="1" fragment="single">NSGDRRNPPQCAPETRDEIHDQIKAWADSPVGKAMIFWLFGSAGAGKSAICQTIAEMFKLNGLLLGNFFFSRSAASTGRSNGDRLLPTLIHQLQEAIPETHPYIKKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED28</accession>
    <name>A0A9P6ED28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED28"/>
    <dbReference type="OrthoDB" id="3013684at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040127338" evidence="1">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="141" mass="14984" checksum="2D1D8EA21D221FC8" modified="2023-09-13" version="1">MISIRYIYALAFAVLTLGSAAAPTDTCTCPPDINGVVGVLHQAWNGGVQCAFPTGACSWDSSGTLLNTAQPNCQRYISPNLGCPSADKTGSPGHLVHYLLQVTCFYDTPDQEFCWWDGTGSLLINSSGQECALNMAPCWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDF5</accession>
    <name>A0A9P6EDF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_769261</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDF5"/>
    <dbReference type="OrthoDB" id="238681at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000005">
        <property type="entry name" value="N-glycosylase/DNA lyase OGG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="12">
        <location>
            <begin position="144"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="48404" checksum="A6C8F0D3E866E929" modified="2023-09-13" version="1">MASATFKSLPVPIAQLSLAAVLKCGQSFRWSILTPDDLVTGTTFDSVEYRFCLKDRVVCLRQSSDTLYYRSAFPDPLPSSDILLQRDNETLLWLRDYFQLKLDLVVLYKQWAAKDKVFASFQSRFEGIRILRQDPWENLISFICSSNNNISRISKMVQNLCIHYSPPLLSLSHPFKPSEMMEYHPFPPPSALATPAVGLHLRSLGFGYRANFIQRTAEMLVDTHGSTLGAESRESSELWLQKLRLSTTSEAREELLKFVGVGRKVADCVLLMSLDKAEVVPVDTHVYQIAVKHYGLKSSKGKANMTPKLYDELSSKFFKIWGEHAGWAHTILFTADLKSFANYGLPNPSSSSSAMNSPSPTKKRKAVALLDTNGEIPTPESLTPVSSQMCKVEAKLELVDVALSNTLHAFPKTGELNMVERVKRRKRGMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDL2</accession>
    <name>A0A9P6EDL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_857093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDL2"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000171">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="739"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="758"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="779"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="792" mass="87650" checksum="28D7906397695635" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEH4</accession>
    <name>A0A9P6EEH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEH4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350880" evidence="2">
        <location>
            <begin position="22"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="12263" checksum="2CCB7B81A0C59AF5" modified="2023-09-13" version="1">MKFSLSLVVTAFALGVNTVVAAPISHSVDVTSRGHEHSDTTPSHEHARPAHDADGHGSEREHEHVSYTGSSASHHASRRELVYDILQERYPSIIQAREYSGAHVARALVEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF59</accession>
    <name>A0A9P6EF59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_855728</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF59"/>
    <dbReference type="OrthoDB" id="2882874at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="147" mass="16262" checksum="F2B4085772A5D51D" modified="2023-09-13" version="1">MDTYTIFCAIQHEWTPFPVDIKNDSTVGHLKDAIKAKNTARFGSIDAHTLTLYRVDVDVGGSTAKERQAALAQMILTESLDPLKKLYKLYSSQPPDDTIHILVQPPAPEESQALERPAKKQKLGDGTQNIAHNKWGENIHSGSKQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG14</accession>
    <name>A0A9P6EG14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_752350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG14"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="54" mass="6001" checksum="D1D3D22FD3D1540C" modified="2023-09-13" version="1" fragment="single">KKTPPLLACLFCRSKKIACGPPVDGSDGHTCNPCQRRNLECKYPAESRRGIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG43</accession>
    <name>A0A9P6EG43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG43"/>
    <dbReference type="OrthoDB" id="3199820at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="918"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1186" mass="128276" checksum="D60C3B6DA111C997" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGG2</accession>
    <name>A0A9P6EGG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mechanosensitive ion channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_813892</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGG2"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF11">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="407"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="679"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="734" mass="82661" checksum="26E1A09276723F92" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGP3</accession>
    <name>A0A9P6EGP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_766200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGP3"/>
    <dbReference type="OrthoDB" id="3226845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50258" checksum="63B98D6117091646" modified="2023-09-13" version="1">MQAYPSPSAAQTTTITLTAPPTQQSKSSSDPIRASVSHLLSRCFSLPCSTAAQAFAQLVQPTARFQLALDALLPILDSDESAELAQRILVSFILYSLYVPHPVTINPFKSALLVVYVKEREKALVMANDGGVCPNEQFVWVLWKILKGDGNDIGPYSPSTLSRCPLPPKLRAINLVLDEELYHNNSDIDDSTYFYSHNTNRRSASSDTDESVHDKLNLDITSPVHRISPDYSPRSPFGFEEDKRNERLIQAMRLLLAARDRVLSLSEQRTIVPMISEIANSRFITSIDLTPIIATNPTVAHPLLVALLTNPNPEKNEPRPFLDILPFLAPTLATFDLYGRLLRDQTRVTVPGYSTIADLVLVEVLGRFIHECINWLDQAEREEREGNISDDRFAKGLQNLCRFYTSLIKLSIVDPTCDADSTEIAHFSLRNARFEEANALYRLIATSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGX8</accession>
    <name>A0A9P6EGX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_791555</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGX8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9528519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="558" mass="62411" checksum="7F5010EE642C04ED" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHI3</accession>
    <name>A0A9P6EHI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Integral membrane protein S linking to the trans Golgi network-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_739087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9529015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHI3"/>
    <dbReference type="OrthoDB" id="542931at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="209" mass="23563" checksum="A7406490215D55CF" modified="2023-09-13" version="1" fragment="single">MAPEKTTLSNWDPVLLISQIVSMQTLHYLTLSILIPPLLATFAEPNSLHYEGGAASVGMIMDWREMAGRPTVIGVPIGERWWAWSGGKKVGNGWAEDQWDGTMDPRRGWIIAVCWIAACSVDIYFLYKLVRRPRLVLDFALTLIFNHLVLTTYYAAALPTSVFYWLVLVGGAVLTIIFAEQLCVRREMTEGLKIRPEDEEIEEMEMGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHK8</accession>
    <name>A0A9P6EHK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHK8"/>
    <dbReference type="OrthoDB" id="3363417at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="21994" checksum="65E25026A1A6E688" modified="2023-09-13" version="1">MTISDFASQIAQISPLSIPGLLWAWYLEYLWNYEGNSWVARTAYTFRVLAVLICLPFVIFGLLDIASYIVARTLGVVDVVKASTSDKATVHGTTDAPQVQIQIQDDSSTTSLENSLYSQSDRNSGIDHNIHNLSQSSLASSSHGNGSSFYGENGNLRLAGVGVFSPMASQPPSPTLSRQQLSPEVKEQLRHRTHQIPVQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIC0</accession>
    <name>A0A9P6EIC0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_265409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIC0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="72" mass="8586" checksum="0CE22C974B2AF9DB" modified="2023-09-13" version="1">MHLFDVFVVHPLSRIMIIPLCSHTSFFFFFFFYLYVPTWRPHPLLHSAIHHLLYHAPSRVLLLSPSPYALHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKC6</accession>
    <name>A0A9P6EKC6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_850079</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKC6"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000173">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier protein] reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="254" mass="26791" checksum="5C0CD126614964AF" modified="2023-09-13" version="1">MASSGSLRGKLALITGCSGGIGSATARVLGKQGCAIAVHYNSATTKAKALVSELKALGVKAEAFQADLSDYSNVHRLHEQVVEKMGHPNVLFNNSAIANNAIGITGDIEKISVEEFENTWRVNTGSSFLLTQLCIPNMVQNKFGRIIFCSSVAAKTGGVVGPHYASSKSALHGLLHWIALRYAKDGITCNAVAPALIIGTTMFDFPNDELKNKIPVGRFGLPEEIASVVELLATNAYMTNKIVTADGGWVSGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKG8</accession>
    <name>A0A9P6EKG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_104574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKG8"/>
    <dbReference type="OrthoDB" id="2378324at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35569:SF1">
        <property type="entry name" value="CYANAMIDE HYDRATASE DDI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="39"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25658" checksum="E38162CB4EAC53AE" modified="2023-09-13" version="1">MNNQGLSPTLAAVVPTIPQNEACIIALKAAHQHLSTPIFNHSMRVYHYAQWFTDNDPNIQLPDAQSFDLQTPTPDLIFLASIFHDFGTARCSHNDKEPLRFEVEGANAAVNLIRKHSYSSSSYREVWIAIACHSSPHIAEHIGPLSRLIRLAVQTDFSIISKRKAHDLAEGLEMQFPRLDVEKTLSDEIVKQALERREKAPHVSWPWNLLRAYEEDPGWEGVNKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKL5</accession>
    <name>A0A9P6EKL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_161640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKL5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9723" checksum="D9EC6F20D083A543" modified="2023-09-13" version="1">MERCREELWAVQVDLGDDYLRIALTLSSGDFPKRALLASGNRTLMFKENMRVESRALLSSSFTTRRIPSAGTRIFTQNTHPYATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKM4</accession>
    <name>A0A9P6EKM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_850587</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKM4"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF6">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="619"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="793"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="833"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="873"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="913"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="151"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="680"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="271"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="999" mass="108600" checksum="CB60D3B900FB5D5F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKX3</accession>
    <name>A0A9P6EKX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_148245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKX3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20731" checksum="4C5AE12DE358432E" modified="2023-09-13" version="1">MPKTRIYNIKMSPGVFDLHKDQEYKPSFGNLATKFFLNHRSLSIAFLIKSVIFFKKNEVGLVKTDNSGNQGFGNPTVEGKNIPPGLPDPSPVTWAITQEITLEKYQPVVAGGLPVILFSVFQELEERLRVSCERYCLDPNRLPIELYFAKRAANRGTRIFRLSQPLPTTKMSAYFSYFSHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL05</accession>
    <name>A0A9P6EL05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_881774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL05"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="303" mass="34664" checksum="E9586FA23F7DC795" modified="2023-09-13" version="1">MKRLYAIDYIAKWWIRTYNIDTSLPSESSIRCRSRGINTFGDGCGCTTVVDVDLCSLRDPSSLIHLRVAPSQGSYTSDTGHRQVHFPPQWTVVVVVVFGSDCWYKISTRTANSNFAKFFDPDGYLRVVLDTWDPRSRTPKEVEAVGSEDAGENEDPITALRTKDEDFNHLAAQFRIVEAIGVRVVRYECPRKVVWCGDWISDSALEELNKALAWGERGKWSMMGRHDEKDLETAQEQNKGSQSRAIVTLRPRRSFGKDIPSGTINDENNQVCEAWRRRKEKDMIYRTEEEDVKIQMVIASEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL43</accession>
    <name>A0A9P6EL43_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein PBDC1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_849368</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PBDC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL43"/>
    <dbReference type="OrthoDB" id="10248897at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3560.10:FF:000001">
        <property type="entry name" value="Protein PBDC1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3560.10">
        <property type="entry name" value="yst0336 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023139">
        <property type="entry name" value="PBDC1-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008476">
        <property type="entry name" value="PBDC1_metazoa/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021148">
        <property type="entry name" value="Polysacc_synth_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410:SF9">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04669">
        <property type="entry name" value="PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide biosynthesis" evidence="6">
        <location>
            <begin position="17"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00061201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="20853" checksum="224F6E8923CE1048" modified="2023-09-13" version="1">MSTQKFDPNNAQNLLEIEKQFAVKAVEQAQTYWNLLEKVDPKDLKLTKYDDEIYEHTMKLFPELAEPPHDKVVKIDEDWMKSDEGKKRWREFMDTYKDKVKDYNFGSLIRTNAEDEYGETNTIFVTRIQFYAFEIARNRLGLNAKAHEIAKVEAEKERLKKEKEAKAAEKKKKTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELA1</accession>
    <name>A0A9P6ELA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">UbiA prenyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_761693</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELA1"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000008">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="35806" checksum="F99426B4DE76B4A1" modified="2023-09-13" version="1">MKSEETTRLLPSNAQKERLKFPLGLVSPTVRPYLELIRFEKPTGTILMFWPFAWGLTMAAYREQLPLDVYAFDLVKCLFSAFIVRSSACTINDIFDRKMDAAQAERCRTRPLASGRISVFAATTYLLVQYAIGIVFFYANLRDLAFAHSLHSFMIYPLLKRCTHWPQAWLGLAMNFGLIASWVAITGSLDSKVIGAGVTSCWGWTMLYDTIYACQDIKDDIKVGVRSTAILWGAWIRPLLVGCGLMFLAFFALAGYLNNQGPAFFVASIGGLAFHLIYQYCTVDLEVPKSCGDNFIGNGRMGAIIWAGLMLDYLHSLGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELC6</accession>
    <name>A0A9P6ELC6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="3">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_787230</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="3"/>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELC6"/>
    <dbReference type="OrthoDB" id="10261027at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="233"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="641"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="782"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="499"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="566"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="722"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="566"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="729"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9531187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="840" mass="94268" checksum="6B7A94882BBC37AA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELH7</accession>
    <name>A0A9P6ELH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_119302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELH7"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="23705" checksum="628D520AD82A47FC" modified="2023-09-13" version="1">MTPTEDIALVVVVGLTGCGKTTFVNQASGSTFEVGHSLASCTTKVVQSLPFRVPSGQRVILIDTPGFDPSDSKKSDKQILEDVKFNVAKIYGAGKKKKLAGVIYMHRISDPRLGTTTISNVKRALKVVKKMPRKNVVIATSFWNQVDEAEGIQRTKELESGECFRPTLRQGGIMLPFNPEHGESAKKLVARILEQEEIQDSPKDWDSVPGSMWCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELQ2</accession>
    <name>A0A9P6ELQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_891744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELQ2"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="82" mass="8484" checksum="A82142F29DD74FE3" modified="2023-09-13" version="1">MASNLNVHNILTSTVQHSSWIILDSKNVNHLYAVNEVSAGAVQACTIDSQGFLGTPTDIITSGGDGPAYATVLSSRAVAVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMS4</accession>
    <name>A0A9P6EMS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMS4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="88" mass="9871" checksum="CD28BACEC9B73B65" modified="2023-09-13" version="1">MSQETLVVPPTAHFPLLDRVSRQPSLIQGVSPPMMAEVTLEDVNQMMTCQRYSINITGPGWFLALFAIMAFLFSLIPQVHVHVSHHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN98</accession>
    <name>A0A9P6EN98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Voltage-gated hydrogen channel 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_847567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN98"/>
    <dbReference type="OrthoDB" id="427456at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030171">
        <property type="term" value="F:voltage-gated proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24103" checksum="894A10E9974FB851" modified="2023-09-13" version="1">MSERELLLGGYNTAPGSEALGTKPESTYHRCQRKTAIFLEHPVLHKTVITLIATDAACVLADLAFSFLSPGCEPPDNAGSPTWLLVLANISLVITTLFLIEIPLTLWALGVQYMNPFGDVPHAGLHAFDATVILTTFVLEVVLRGKEKELAGLLIMLRLWRLVKLVGGVAVGAGELQEELAEQLADTRRELEMARTRLANLQGENQALKERLSQIGPQAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENG2</accession>
    <name>A0A9P6ENG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_848167</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the RIX1 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the IPI1/TEX10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENG2"/>
    <dbReference type="OrthoDB" id="361362at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024679">
        <property type="entry name" value="Ipi1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056">
        <property type="entry name" value="REGULATOR OF MICROTUBULE DYNAMICS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16056:SF2">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12333">
        <property type="entry name" value="Ipi1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Pre-rRNA-processing protein Ipi1 N-terminal" evidence="7">
        <location>
            <begin position="164"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="501"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="823" mass="90618" checksum="8B28E5E0E07FF622" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENY4</accession>
    <name>A0A9P6ENY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENY4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="8402" checksum="741FE8D74B3941C1" modified="2023-09-13" version="1">MSIESFQGPLSSSCGRSQNPKGSRLQSKFQRPIQRRAISVSRLPLRGSICQIVGSYSTFPEPAERHVKTASCCVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ11</accession>
    <name>A0A9P6EQ11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ11"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="56"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="39708" checksum="26430EAB35ED5544" modified="2023-09-13" version="1">MSDDEDPDFEGLIFVTVPQPADDDGTTEWLIRGGRTKSNIFHTPGYPAPVPKARLPNMVIVKETAEMGMGLFATCDIKRGELVFAERPLLVSPCFIPEQDFPHLTDEADERERQLFRAEFESYLKLAFQGMSFEKQEAFMSLSNCKSKDSFGPLLGIFSSNGYQIDLDDDSESLDKYGAIGELAARINHSCRPNVRQEFDRASFSLRFYTKKDIKAGDELFYCYCNIRGTAAERQAFLNPSYGFVCVCPSCVNATLASDELHSGFASEASRLGDLFPENKREKEAVDRTVLESMIELEKRMIEEGLEGEFSFDQLLLIIGMGYKSLGMLAEGESYTKRCPKTRFDGPEASEDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQA9</accession>
    <name>A0A9P6EQA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerol-3-phosphate O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_589325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQA9"/>
    <dbReference type="OrthoDB" id="2427554at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016287">
        <property type="term" value="F:glycerone-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="3">
        <location>
            <begin position="50"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="764" mass="84478" checksum="ACCED49DC565A7FD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQL7</accession>
    <name>A0A9P6EQL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_845845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQL7"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="12321" checksum="3D266011316105EC" modified="2023-09-13" version="1">MTPPKPKSGLQKQVLSLYRRALRMTGTKPQATRPKFLLFFRYTFRTNAKQISPRNVSFIEHLIRKGTRQIESFEDSAVKDCWVSEEMVRWNEEWKSAAQRTRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES37</accession>
    <name>A0A9P6ES37_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_411331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES37"/>
    <dbReference type="OrthoDB" id="2348945at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="642"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="701" mass="74970" checksum="26652F8651FB9F3B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES39</accession>
    <name>A0A9P6ES39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase endo-1,3,1,4-beta-D-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_902699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES39"/>
    <dbReference type="OrthoDB" id="10019231at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="30000" checksum="FCA38303851C1C46" modified="2023-09-13" version="1">MSCPNCQEGFILPGEPTGSIETELLGAYHAPSPSSEPKKYTVLLLTDAFGLPLKNNKLLADKLAQRLECDVWVPDIFAGRPIMPLDTMRLPDRAGVKFPWWKWAQFFLSMLPNIGAVFNATSGKVDKRVEDLISLIKEKKGYEKIGAVGYCFGGSVCTRFAARSDVISSVVIAHPGPFTVEDVKKFTVPAAWACAEDDHYVPVKLQNECEAELASRKGKENYIDYEFKVYPGTAHGFACRPNFEYPDVKDAYEKAFEQTVTWFQKTLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESL1</accession>
    <name>A0A9P6ESL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_6765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESL1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12168" checksum="B2B01F766A20391D" modified="2023-09-13" version="1">MSPRNLEEVTWFRHSSCLAALLLVNWDTVRLALENFIERYCAHTHFKIIAHSVCILGEILTVPYTTKVPAAHQLHMFPPPKVRFFHSSGPPTATPGFLFDVSKLPAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU31</accession>
    <name>A0A9P6EU31_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_754491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. Sedlin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU31"/>
    <dbReference type="OrthoDB" id="18320at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14854">
        <property type="entry name" value="TRAPPC2L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044760">
        <property type="entry name" value="TRAPPC2L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="19959" checksum="C201B478CC0A710F" modified="2023-09-13" version="1">MPPSLKLNAVAFVSPQNHPILIRTFNNQDEHAIKYHYIAHTSLDVIEERGEFSIRRIICVQLIFSVAAAGKAFECYLGLLFTMEDVAVYGYITPLKVKIILALALSDAVVKDAEIITIFKALHMAYYSSVSNPFLKLETVGDSSSDQATILAVGSPKWKLFRRRVDDINWAVGNLNSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU52</accession>
    <name>A0A9P6EU52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_879195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU52"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="251" mass="27970" checksum="03F2D83ADC2421B6" modified="2023-09-13" version="1">MVDWISPKLHEQCYQAFLKMGIHHHLGFRIASLDEGQTVQMAHVFYCTCLLDDRGTIVLTRLVKALSNLSLGLASTNLAIRTLAVWDFNRCLLVMVIILIGGHWIFGLAQAWSYKASWIPGSGCVPRQSRFILSAALSIYSVCFDGLMLILNAYKLGFRTSPDLRVMVVATGRKRTLTSLVIFHGSSYFIISFLINLCLIIVILLDLPVGAGSLVGVSTAVINTVTACRAVRSLTLFFKPDEDFKTYWFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUX8</accession>
    <name>A0A9P6EUX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_842312</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUX8"/>
    <dbReference type="OrthoDB" id="72772at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="791"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="876"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="791"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="836"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="888"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="928" mass="100925" checksum="4B85211F81ECD4C6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV96</accession>
    <name>A0A9P6EV96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maintenance of telomere capping protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV96"/>
    <dbReference type="OrthoDB" id="5594977at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018814">
        <property type="entry name" value="DUF5427"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10310">
        <property type="entry name" value="DUF5427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="46597" checksum="B2EA15A7117AF727" modified="2023-09-13" version="1">MASKKSRKEEALQFLDDLDSFSPPGAGTTAPSAPKGGPTTGVPAEGEAEVLAFLDEITQKSTEPTRAAAIHSISRSSTPISRKSTERVKIGGSGPASSSTTSLSKTLSTDGTKGKERDASAPATTNTPLTQGQGAGWGWGSVWTTASAAIQQAKSVVDEQVKHIPKNEQALKWGQGALEYAKTAQLDKLGQDFKRVGLSTLTDILNVVAPPISEHEVIQVWLSHDMQGYEGIESLSYRALARILEQVEGGDLVLNKGNETKPKETGQGRELNAVDDYETALKVAQVNIEDVIKKNVHVTETTRNPNISTTYSNVFLRVQPFYTTFTQVGQPETAEPERHLQFLLYLFDPPHKLTHTTVTQVVPSKWIALWDDYDWVEDLVAESLRVGVEVLGQEYVVSRMGWGKKEEHGKEGSTSVDPGEHSDKADESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI52</accession>
    <name>A0A9P6JI52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157978">
        <property type="protein sequence ID" value="KAF9521868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI52"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="16677" checksum="F0D97F8AEF8A5166" modified="2023-09-13" version="1">MDPHSIAHRMASQNLDLAAVQQEIELIVAEKDLIEKNLQDAVERFQQVRAMAEILEKRVEDTARVVAEQTILYKSLLARIKEAEIKSDEVQLKLEYFETQTTKKYQERIQQLENECDGLRQINASSETKATMLEACVKALKTELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIE1</accession>
    <name>A0A9P6JIE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIE1"/>
    <dbReference type="OrthoDB" id="3031270at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="358" mass="39667" checksum="459943C98963D519" modified="2023-09-13" version="1" fragment="single">VGEDPFDFPTAVPYAPPILLKPSRTEGSEAGLLNATGKRLAADEAEEVSTAQLKRQKTRLAAASRRRVRREEAANTSRFIRPKLIDKYANGATPLETKLESDKLKTSATSYEAIPEHRSQSSRDTFPFISAGKKHSLPSVSPRSPTNKQDSSAKPSPPPTRELSALSGISDLRVRGVLEKLMKDDGFSYKAWDGSNSHPVLDSLKRVVVVLIGKPGGDYDIASERVFKFIQHLGNSEPFTRGETQHLRGKFPAVNAGISLGPGCTFPSRVGVGSHDEMVEKLLNNKDVQRLASHQDAAFKLWHPKLYAHYDQMSVKLRGRIPSLQKNFKRSVFTSMAFNFPPNVRTVQHRDIRNLPYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIV6</accession>
    <name>A0A9P6JIV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_92268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIV6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="100" mass="11487" checksum="CC142F61E9112403" modified="2023-09-13" version="1">MARHQRLNYPRIFLSRSALAYCRSRSICTIYGMRPWHVQANIDSLRSSNRTHLLKSRTLKNVAHQLSLSNLKHFDICLYIVYVATISLVNSFGIVGPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJM1</accession>
    <name>A0A9P6JJM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_775521</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJM1"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="14">
        <location>
            <begin position="115"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="306"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9523412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="44476" checksum="DB08F522E7551C58" modified="2023-09-13" version="1">MPKRNLASEHEEEDTSTPSSSKRARTGSDEDDEQIRTRTQRDRKTKSKNARHHADGDDEDEEQADLETALQNTQKDEIDDEEFEVKFGSQVRAHLESKKRVQGTVAEHGIIEYVEMAQFMCHKFLKFTFGPQVNFIIGHNGSGKSAVLSAITVALGGKTASTGRGAGLKSFIREGQNQAEVTIHIKNQGDEAYKPKEYGKTIIISRRIYKEGSPTWKIMNASGKVVSTKKDELAAICDHMNIQVDNPMNVLTQDAARQFLSASAPQDKYKFFLKGTQLTQLSDEYELCLKNVTQTQKLLAVKKEAIPDLKVRMREATIRYEEAQKAREQKQKAIDLKKELAWSHVAGKQEELEKQSQEVGKLSKRLPKIKESVKKAEVCVITLYKFILTLSSQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJN6</accession>
    <name>A0A9P6JJN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157917">
        <property type="protein sequence ID" value="KAF9523457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJN6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="485" mass="54807" checksum="1F59025649496362" modified="2023-09-13" version="1">MNTPQLPLELLDRIVDIVDSWNYNDRLTTLQACALVSWPLLISCRRRLLRVTLFELGGEPSLQHNMFVDKSIPTFLDFLEGDPCLSYRRRTRGYPRLSSNIRKLHITIGPAPIAQVTFTYLSTILSRLDHVEALYFQSTNNLSISESGLLSGLLDLFKTSSPLKLVSFNKGFRVPIQLLLSCPSLRQLWLHKMNDPATDILQPFLQFSAGSIPRLQQLDIDLASLDILASYLYHPRGTQMFSHLEELTTKDIDATRHTLGSLYKLLRIASNTLHTLHFNFMLGYGDPNSNLQMTTSLPPSQKLDLSTLPNLKSIHVDINDHEPLSIACFTLFHSLISQAAYPTTVQHISFILEAPIHPHEETFQQLHSLLFDEAKEEWAELDTLLCGSGSGSQSQTQTPAPCNYPSLETFHLEINIDMTPYSEDELPWEESAVDVELQLKKSFAQSLPKCSSKGVLDIAVFLILEDLDDESVDTNDWDAVDREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJT2</accession>
    <name>A0A9P6JJT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
            <ecNumber evidence="13">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_863344</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Complex I is composed of about 40 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Mitochondrion inner membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="13"/>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJT2"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.230:FF:000001">
        <property type="entry name" value="Mitochondrial NADH dehydrogenase flavoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.600:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11540:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13" id="KW-0288">FMN</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="14">
        <location>
            <begin position="378"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00063883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9523129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="512" mass="55723" checksum="EAECED35EF4EB5CB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJT6</accession>
    <name>A0A9P6JJT6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_910756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJT6"/>
    <dbReference type="OrthoDB" id="3266451at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="66586" checksum="291FBC1E1BE06F86" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK86</accession>
    <name>A0A9P6JK86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_775119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK86"/>
    <dbReference type="OrthoDB" id="3341102at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32096" checksum="D48995E15B053263" modified="2023-09-13" version="1" fragment="single">LKWVITASTCPGCKIPANADNILQKAFLRIAYVIKHKDIPSALIANSDQTQVVLAQGSKVTYAPINLNQVSTVGVDEKRAITFLVSLTNDGILFPFQTVHKGKTAASLPSKNCRSWKEASAAEFLFESSLTSTYWSMLETMRHFVNASLAPHFAKVKLKLHLLPEQCSLWLIDCWSVHCSQAFLDWMATKHYTIIVLFVPAVLTGLSQPCDVGFQQIFKHQLKLSAHNGVVQEVLTQLKGGVAVDNVKIDVTLKVLQDRTVYWLWVAFQTLNNPATVKKASVSHFCNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKF5</accession>
    <name>A0A9P6JKF5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Emopamil-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_862117</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKF5"/>
    <dbReference type="OrthoDB" id="58557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047750">
        <property type="term" value="F:cholestenol delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207:SF1">
        <property type="entry name" value="EMOPAMIL-BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207">
        <property type="entry name" value="STEROL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05241">
        <property type="entry name" value="EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="8">
        <location>
            <begin position="41"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="23522" checksum="A74A3DC1CFC3FCD8" modified="2023-09-13" version="1">MADSTTIFTATSAYSLGGVVAIGLVAYFAAENILPKNASRTDRFTFIWLAFDALIHFTFEGSFLYLSTFGRQVGNSEGMFAEMWKEYARADYRWGLSDPTVVSLELLTVLGAGPLCVYICKQLASNDPARHYWIIVLSTAELYGGWMTFCPEWLTGSPSLNTSNPLYLWVYLVFMNVIWVVIPVWLMYDSYSHIAGALRQRQVASKAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKI1</accession>
    <name>A0A9P6JKI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_774139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKI1"/>
    <dbReference type="OrthoDB" id="3262464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="71" mass="8145" checksum="00CE0E632A2915D2" modified="2023-09-13" version="1">MTDRRSKIEHVLMEMLQMLKFSFKQGRGIDFSAGTSEADIEAYLLAREAGSIHVAEDVHSYLRRLLTEICE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKJ4</accession>
    <name>A0A9P6JKJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_947190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKJ4"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="48326" checksum="75CD44F6EB4A8B90" modified="2023-09-13" version="1">MSSPKLPLEILTVVIDALAASCSDDESLSELMQSAALTCRAFVPLSRRHIFASVAIDDFNNPHRKPISPLEFANFFTEHSYLTKYIRELSISILATTSQSESAGEVENLFKTFLNIHGLESLSISSSGIYAVMKLSDSPFSSAIQHLLQVPSLSRLRLSHLTEVPLDVLTTNLKHLSLESVNWKSTGEFSSFDMPPPDLEVLTFNSSHSTRALLSLVRPDNQPVVSLKNLRRLEIMGMGEEILKICRMVASTSKVLASIYLSVCMHDGFTGLYDAISPSLNTLRHLVLVACTEYQDLDPYQHACEELEKIAMAKIQTITFKVNTDCSIEGTNENNWDRIDELLTLGANWPYLTDVRLEVTIWRPKRPDRTFEPKVCFKRLLASKCIHFVYECHNKVFTEKYITQSEGLRAVDVSHYTISSSSSLHANSTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKM1</accession>
    <name>A0A9P6JKM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_886269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKM1"/>
    <dbReference type="OrthoDB" id="5106486at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="75"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="235"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="865" mass="97971" checksum="DD2D97677313A01A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL13</accession>
    <name>A0A9P6JL13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_860529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat rae1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL13"/>
    <dbReference type="OrthoDB" id="256303at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000190">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="6">
        <location>
            <begin position="35"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="110"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="264"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="358" mass="39033" checksum="89CB32AC19D3F19B" modified="2023-09-13" version="1">MSFFNTATTTPANTSTAAEKDVEVADPPTDSISSLSFSSQADYLAVGSWDNSVRIYEVGANGQTQGKAMYQHQGPVLDVCWNKEGNKIFSGGADNAGRMFDVTTGQATQVAQHDAPIKVVGWVDAPGAGILATGSWDKTIKYWDLRTPNPVATVQLPERCYTFDIQYPLLVVGTAERHVQIFNLTNPSTAYKTIVSPLKWQTRVLSCFTGTSGGGSSGFAVGSVEGRVAIQYVEDKDSQHNFSFKCHRRDSTPNAKDQALVFSVNNINFHPVHGTFSTCGSDGTIHFWDKDARTRLKSFDAQPGPISTTAFNRNGNIFAYAVSYDWSKGHSGMTPGQPNKILLHSCKDEEVRKRAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLG5</accession>
    <name>A0A9P6JLG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA A64-2'-O-ribosylphosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_897508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLG5"/>
    <dbReference type="OrthoDB" id="45256at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043399">
        <property type="term" value="F:tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019988">
        <property type="term" value="P:charged-tRNA amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007747">
        <property type="entry name" value="Ribosyl_Ptfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="3">
        <location>
            <begin position="12"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="2">
        <location>
            <begin position="346"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="442" mass="49708" checksum="4C75DAD6C1E43C89" modified="2023-09-13" version="1">MNLNKDNVLSYIRKESLDIYNRLHSIEEDISFVNQVYEAYRDAPLLPNLRCGAWYTDPKIATVLPAYFKSTDGHFNNWSFNLRRSNLHLLQLLAEKECMILVDSTRSGKRIPDALSKTVPIWCAVINRASLVRFPELVETEKIIWDTDFYTPPAAVSTQEHHQIEQRLDDWANSLAKSSFELPRLPRPLRPVWITPASTTFPELPTSPSTIGEFLPVICVSASKKVDEGLERRLGGYTYVQGSGDDHELWGMGLTPAMFWEHRQDLLKADRLDLPDLVKALVSQQPALLLCERKFPCPTLIQKVHGRLQLCSTLELADMPMEELGITKYLLLTCATPAESTASQRHIHVTPGKKGKSHFLTRVLPESIDFIQKQLYGGYDTLIACDTGKDLSVGVALAALQLFFRDDGSLKLSEHSDGHTASVHDLSGSSPAGHKRTRLEPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLM0</accession>
    <name>A0A9P6JLM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_549694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLM0"/>
    <dbReference type="OrthoDB" id="5271586at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="29618" checksum="AA9D18FE123786B4" modified="2023-09-13" version="1">MVLFAFSSNPGNGYVVSCGTDTAWQSIPEGLSDKIKATAAANDTVLSISVGKNDWFINTSSSVCCSQSGAVMTFLSSAEAQNNNIRLADIEQFVFMPNTPTGYFCATANRQMWSGLPKSMADNIRLSSSKSDIRCVAVGAGEQWIIVREDGSFAFSGISDDLAKTLKEYRAASKNIKYITFSVDKADYYFVEFEDGSTLYLFPTSWQPQIREYTNKSQDMAIEQSNRRNAGSASARMASNARSAALLDLATFNAEVQMLRNAETCARMALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLM8</accession>
    <name>A0A9P6JLM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_885980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family. PalB/RIM13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLM8"/>
    <dbReference type="OrthoDB" id="167576at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="128"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9524839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="843" mass="94106" checksum="1F31248F600F1E9B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLR4</accession>
    <name>A0A9P6JLR4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_859558</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLR4"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040463469" description="Glycosyltransferase 61 catalytic domain-containing protein" evidence="9">
        <location>
            <begin position="26"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="10">
        <location>
            <begin position="196"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="534" mass="59505" checksum="7FFB8E4892761F11" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMB7</accession>
    <name>A0A9P6JMB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMB7"/>
    <dbReference type="OrthoDB" id="2833246at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="17865" checksum="31D856D8E66223FF" modified="2023-09-13" version="1">MIQPETIACLATFAGEKATQLVLQHLNGVENVLNLRADARESYDDWQWGIKAQDDGEQVKYVYPNVPSSSKPDMINLDDGQEIVFGGGDDGVKLGKGPLPLLCNILLTLARVLQMSGAADIILQMQEDADDSNLGHSYIASDLRFDILRSKLLLHPTRGSGVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN02</accession>
    <name>A0A9P6JN02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN02"/>
    <dbReference type="OrthoDB" id="3226519at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="23674" checksum="A28BADFE972E8ABD" modified="2023-09-13" version="1">MVDQPNHIKAAYAVEYSPEPTSFSALPKMQLLTLFPIFILAISVAATPIIDETYCPGAKIVSETYIGKDKNVQVLSLSCDTLPRIAPKENVVLPRAANVLNVCASHCNNNCFLPAGGGPDPNECHVISDALLYEGQNTGAIFQVQNGTVAGNPTVMQYRSCKTFFVNQDTQILEFCRSTWAGLVDSLAFNCQAAQNAHGGNCVADDQRWYVQVQSSTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN68</accession>
    <name>A0A9P6JN68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_884433</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN68"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="300"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="351" mass="40239" checksum="58955F87F91CB1BA" modified="2023-09-13" version="1">MYNYLVEPFDYNDIVLDLHDISLLLTYERGITEPRFRHAKLREVATGLSDFQTIKLPDAPKPKWSEATIPRTGYVFVKPKQSLSKAESEELDLPSNMLLKPVSTSLQNLSSKQLETYYWQPRNHDGCYRTVRLFQHFMDLFPSEFTRIMVRAVANNKPRTYTTLASDRLIIEMKLRGPKSMNFTCALPEGRSYVTGSDEVSAHVVLAFPAPSDADDPQTILDLASLQFGDAGRGCKGRGLFVLEPVQQYKERLKNFADGNNFLEDKITQRITSTPDDDFLKNVANRAKERWEKRKTDFWCGHCGSPARNDPLLRCSKCQQAHYCNSEHQLAAWPFHKHFCVDPSAPKPQWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNC3</accession>
    <name>A0A9P6JNC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_857595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNC3"/>
    <dbReference type="OrthoDB" id="6474464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="513" mass="55947" checksum="755B9D631174EB1D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPJ5</accession>
    <name>A0A9P6JPJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_854691</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPJ5"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040244738" description="WSC domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="30"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="138"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="411" mass="43374" checksum="8F435A51533588D6" modified="2023-09-13" version="1">MALTGVITILLASLSLGIKAQSVPTRLPGNWSHVGCYTDISTSRTLAATYFVSENMTVESCMSFCSAANYIYAGVEFGNCDSTIQIPSQPAPLGDCYMPCNGNATETCGGPVRLNVFNSNEPPPVIVPSITSSHDAGLWTYQGCFTDTVNARTLGTGINIPGGTTAESCTAACQAAGGYLNAGLENGHECWCDNSIHAPTQRTSDADCRMVCLATHREYCGNQNRLAIYQYSASGEPPGPQACLQTSLSNFTLQAQFKNPPINGPLSVPIKVVVVELVKNVLWTVLSACPLCCSEWPALSMQNSIIKPHSVAIPTQEMAATYTNDGESPGFVASIPAFPGFQSYCTMTDSAAPPGSPPILAFDGKPDAFSLCTNTSANARLDVVFSPVTGHPHYLLDDCQPINIQVITGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPJ7</accession>
    <name>A0A9P6JPJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_303282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPJ7"/>
    <dbReference type="OrthoDB" id="2122304at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371:SF1">
        <property type="entry name" value="BLR7753 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35371">
        <property type="entry name" value="INNER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="16772" checksum="96BC1D515AC9E71F" modified="2023-09-13" version="1">MGSLSTNYSLYSIPAMVLVSYYPTAVKGAIMTNLGIYNNVVPRGNLPKLQAKPNPKVSPELAAKLARCEGAHYNGLENLPFFGLSILASNYVGLKPEVLNVAAGLYIALRVLYNYIYINNTKVSTSFVRTLVWNIGIAIPFYLSIKAAANVPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ18</accession>
    <name>A0A9P6JQ18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ18"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="645" mass="73647" checksum="ABB7B929ABD55087" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ58</accession>
    <name>A0A9P6JQ58_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ58"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8400" checksum="148CFD96C1306B4B" modified="2023-09-13" version="1">MWDLLHDHRCILIRCLSLLVSNGYLVLVSLLLHLLAAFFQILFSELITAKNLENGIVGRYQVMSMKIKDAWPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQY3</accession>
    <name>A0A9P6JQY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_187384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQY3"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="185" mass="20415" checksum="AC39E7B5730E5CCB" modified="2023-09-13" version="1">MDQIPALDLFSLKGDTVLITGATRGIGAACAIALAQAGASLVIVVRPRLAKGSIDEAGVEEAKAVKVEDAKEKPNEGKENEAKENKDPAIIAEILTASPRTKREQLYVIECDLGNMEDVKSLFPRALQLLPSQEAQINILVNCAGIQRRNKAVDFEEADWDDVSIDFFYFCDFRFLDRFSFFFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRD8</accession>
    <name>A0A9P6JRD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_852224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRD8"/>
    <dbReference type="OrthoDB" id="3359595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040413557" description="TM7S3/TM198-like domain-containing protein" evidence="6">
        <location>
            <begin position="37"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="7">
        <location>
            <begin position="121"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="39894" checksum="38B815E229C538D5" modified="2023-09-13" version="1">MARPSTIHTMFSHFQPSALAFVLMLFLFSTVQTSNAVPLQLDLLRSSISSQSNDNLYVPDSSKPSYNLWSPFIILPHFRQRTNAEVITSTLSHRDLELPSQGPATDGGGKGYDGPAIMWIVFTLVIGPPMALAGFKGARISSGVGAGLFCSMSAWLAIVNSVGSDGIPDLVLNLVSLVFFAVGFFCGFFKWGRYVGMVCLGLEGGLALGVRFIILRPGLLVNGLDLFKLNWAIVLLLGAIGGMAVVPEKTQRWALLVGCASIGSFLTFLGADLIIHKQSGMSRGLRLLYDRNASHFQDNVAVGYKPSIVVMILVGVSIGVTLILACGQSYFFKAPFDSWKQVEEDKDGSEAIGISQPTRGTHTKAASFASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRE0</accession>
    <name>A0A9P6JRE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_852470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRE0"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF85">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G00710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="48"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="55899" checksum="501122770521D8ED" modified="2023-09-13" version="1">MMDEKAEARMSSAAVSRETGIEFASDTKVVHHDSAAERKAIRKLDYEIIPVMTMFYLLSFLDRANIGNARVAGLQKDLHMTDRQYQICITITFVPYIAAELPSNLLLRKIGPRILMSTVLTIWGIIVMSQGFVKSYAGLATARAFLGLVEGPMFPGIVLYLSGFYTRRELSFRIALFFSAASLSGAFSGLLAAAIQQMDGIGGKPGWAWIFILEGLFSFLMGVAGYFLIPGTPHQSKLLTPQEKDLVMERLERDRPSIQPIDKFTFREVWRSMKSPQVIMVFIMFFLVGTTLYGLALFLPSIVAQLGYSKNRTQLLSVGPFAGGFVVTVLSAIISDRLENRGLVAAAISLLAVAGYAMSLGAKNEFTRYGALYLMVPGVYGAVPALAAWMSNNSEPHYRRAASIAFGFVATNSGGVLSTWRFPTKEGPKFTKTTIMNLVFSIVVVLGCVANTAYLHWRNQQKKRPGYREEVLARFASVSADERERETLAWVELGDRHPDYRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS68</accession>
    <name>A0A9P6JS68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS68"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="134"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="50407" checksum="B23BFECB613A8CDF" modified="2023-09-13" version="1">MEQQPTAVAFKRLDKVREVLPIYPSPTPLRLPELPCPQRKPAFDVPFTLSTHIIPAAYIRTTTPVPVPDSLRQDTSKDEKRQGIKHIHKYMENARKISLSGSEGYPQALWNCVNRYTRNNSNGSGPSTQRITLFFAHANGFTKEIWEPMLGYLLSSKSSQIIDEVWTWEAVQHGDAGLLNADFRSGSFDTTDNSRDIVNFLCNFLPEKATTEALPLHLARVSETKAAERAQRGFMGRTLVVIGHSFGATSLIHAASLFPKLFTSLVLLDPILLEPFVQEEIDRTIGLVLGAIGRREEWPSRPAALKSLFETAFFRSWDPAVLSVYVDSALYDTPQGTARLKMSGIQEATIFLDLQTPTEAFQRAIEIEQQIHLRFILPGKPGLVSFAGSDKRMWLRTGNSTNTKIRKAGHLIPQEAPRELAEDLNRYLLESFNSVNRDLHKAHIRSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSJ8</accession>
    <name>A0A9P6JSJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_52602</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>prephenate + H(+) = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSJ8"/>
    <dbReference type="OrthoDB" id="983542at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000034">
        <property type="entry name" value="Chorismate mutase/prephenate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="8">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="31327" checksum="55729E56E0C4A13E" modified="2023-09-13" version="1">MGRMAGDKLPVAILGPLGTYTHEAAFHAFGHHALYNERSSIADVFEALSTGELLGVVPHENSIFGTVVETFDLLRSTSCSIIGEVTLKVEHCLLVKHGVQLEQIKRVFSHEQALGQCRGFLGDRLPQAMTIKTPSTAAAAQAVLNQEQDCAAICSRMCATLFDGLEVLASGIQNEKSNFTQFYLLSSSNAYELPPPVSRDLQRKALIRVVAPATADTTRILDALKLSTLRISRRPSLEPIPFHSTYFVEVQGDQNSNSTKAEWRAEIETGLSRVKQVGAEGSILGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSR6</accession>
    <name>A0A9P6JSR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSR6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="125" mass="13684" checksum="D94E46D7606501DC" modified="2023-09-13" version="1">MGRSVLLCFSPVISHLVLRMTNHSECVVSGALASKNLAPSPIGEPCRTRSWTCAWDPPSGVAGRPSRAFAQFFRDRVFQGSWRVLGFFQWGLSTIERAGRNASQLFGVKRAILQHSCHAANLASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT60</accession>
    <name>A0A9P6JT60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_890428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT60"/>
    <dbReference type="OrthoDB" id="3222453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="441" mass="49477" checksum="147D2CFBE9201A1B" modified="2023-09-13" version="1">MPFTQFPIYHPTTTSAYQPAVFSRSLMSLGHGFAPWQPGAKARPEAHFHRGMGIGDVGFIGQDGALQYRFNIFFPSDHPIQPFTLPRTFNPIEPPLEEWTIRKEPEQFPAGTILTSKGVKASKLSQEPLEVEFKSDAREGAVLILPEGASREDLVESPKLYEYIKANASDWYQFMNDYSDFPTARPVVNGTLFVVTGTDKANFYSSALFPTDEDERMRPTTFKYVEKNVKNRTWQIAAPVRASSEQSMTKGEHPTSVFLRGVTVALSKSLWTHDIAPIPVAVLPLYYIPSIPLLGKRSEIMAHFVKGPHEDEDEDYTPGEAIFHPAILLLQILLEINPDASVAVVDDNIWCPLMDGRTVVHAEIAKLITSIIETFDINPIDGVARFIKKSTESTELTIKEKFQAYIQFFFTGSTRSKTEQQALRKLKKLLSKPDPIPTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT83</accession>
    <name>A0A9P6JT83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT83"/>
    <dbReference type="OrthoDB" id="2976534at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="161"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="623" mass="70843" checksum="B471F6F7FAB08ECE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTX5</accession>
    <name>A0A9P6JTX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTX5"/>
    <dbReference type="OrthoDB" id="3249663at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="357" mass="38955" checksum="B5994B725B0CFA35" modified="2023-09-13" version="1">MAEYTTSSQAYREYMSSRERTAYWIQSHAPYDNGFYSPSVPPSVMDGRIPSRPPSDAGSTNSTPPKMVLRYNDGRPDIPIPHPKGGPSLGRSGSTRHQDPNHGRSRTLSYNHGMAHGPSRSGSSGGPTPSPLRHDDLVPPEEIRILPSFGKSSTATSSRPNHTRSRSVPRPIDRDEEPELPFIPPPHLHSSSPYRPSTRSPHHQVSFAPPAPPHQPWHRSKQSPAAYSPHQSQHSQRPGPGYPAMLNHPPHVGPNGVIYSHSAPLPGHGQYAPQFVTPFPTMGDPSHRHASSRDGGTRGRELTRSLTHSAQPAHHRAAPGSPESLGSDQSGTYYVQSHGQKVHVIVSSRLGVAPFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVH6</accession>
    <name>A0A9P6JVH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PPP4R2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_475218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVH6"/>
    <dbReference type="OrthoDB" id="341898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="35761" checksum="E173C4C77CD55C42" modified="2023-09-13" version="1">MPESTAPFEWLPEHDIVLQKIASTDEVETDWDKLRSIVKHKIQQNISLFMSTTKPPPPPTPYPETVSENGGLKLPPFPPRKLGQLHVSDPPVCFMNDEQVASLKKIIFEQLDQFEDPPFTIQRLCELCIQPKTHYTSVGKYLRAVEKSILVTSSIDSFPPLTQAEIFSAGRSAITLGPTLQSAPSTPLFSPIPFLHEDARRSKSRSPPPTPFTLNPVVPLDEEPMEVKALGMVDEFDDPRPGHLSDHPTALTSVTTIPASSNSPASSGQTTSTSKPFFGTLEQRFVKAEDQMDTSTPPATPLTSTAEEAESDAMELDDDKENTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX74</accession>
    <name>A0A9P6JX74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_901374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX74"/>
    <dbReference type="OrthoDB" id="3037824at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="7418" checksum="E38B004D8F76E974" modified="2023-09-13" version="1">MYNLFLARRNTLALWGGIEAFFFGTAWYSYTRPLPVPALAAVRSNIRQRVPADNYRGIPSNAALSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BD81</accession>
    <name>A0A9P6BD81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_742670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158099">
        <property type="protein sequence ID" value="KAF9521370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BD81"/>
    <dbReference type="OrthoDB" id="3248986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF2">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="54498" checksum="0509168D4172B5E2" modified="2023-09-13" version="1" fragment="single">VDDLCLLWDKGLFLSKTSTYPNGRPVRAAMVPLICDLPAARRAVGLGSHSSTHFCSECDLTLQDINDLDSTTWTPRNYNAHILHATNWRDAPTEDVQDQTFKASGIKWSELLRLPYWDPTRFVVMDSMHGFYLRMFMRHVRDVWGMQVNLEDGDGLPHGDLENLSEDSIAEIQRVLRYEPVAKLRKLKKGELQYLCRHAGLHYGGQKSWMAKLLAQHQRHTPLTKVKAGDLAQLDTLYHTKSKAGLSRTKKALLVALCAIRFAGASRNHHEFNQMNRKSLVEIIHEQRLAEGLVDEDGDLLVTQEKGSTTVLGAHVLSEIRSDMNKIEAPSWWPPSPKHPGEIKWGKFKAEEWRSFCLVNLPITLTRLWGILPKESRQYQMLENYMLLVNAIKIATSRSISHEMISSYEQYMLRYLQGFLRLYPHKNLTPYQHLSLHFGDHLRRFGPTHSWRCYAFERMNGLVQGLPSNSRFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2H9</accession>
    <name>A0A9P6E2H9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158192">
        <property type="protein sequence ID" value="KAF9521259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2H9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="42693" checksum="0ECF8792E5775785" modified="2023-09-13" version="1" fragment="single">MDVDELAGSLQLEPDIPRAKRGLGPHLHDEQLQNLLPSTKRVKLTVETLLPSNKAPRVLSAISGIVHAKSFARRKSARIEAMKKNKVKKQLENQVLLGQIINTGRTSLLAGSTQPISLAPSTEVPVLMTTTSTTLPRQFSGQNVHRSKPRGVIHSPYSRFAIKSTSAHKKHLVTQARIPDSKAKAATTFRVITHNYTGTTGGLGGPSALSTGDAYSKLQHQASSDMDSTHSQPPEIVNPLAYERHLDHPLGLSTYLGMKFDVKRQTASDVDTPPSQIRCLQVPGETIFEEAHNDSESSWVMDAIASPPPTSTFKGPSTYAEHVSASHSSPELQLNADPTASNVNATLFQPNSSGGQSTSKQCIGDTVFPLDSKGDEHSFSLDEDAIRPQAIANEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2N2</accession>
    <name>A0A9P6E2N2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_887933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158077">
        <property type="protein sequence ID" value="KAF9521408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2N2"/>
    <dbReference type="OrthoDB" id="3027218at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="222" mass="25707" checksum="3321A3AAA9D1D869" modified="2023-09-13" version="1">MGRTSKYATETERLAARKAQKAQYRATPRAKELRSEQNRRAYERHHPFKYTMRLPDTPKFVLKLAALPLPLDSTVFKAHLTRTEPFSSEYAVWDNPPPYHVSPLLLSGGLDDTINALHGHRTRLQFETEKARIKSYHQEAHQEVWMEVHQSLFRLICESKTLKKSLRGFKPSALDHQMGCHLLQWKARCIVALTEDWKALSEDTVGIIMVHKKRWHGTGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2Y2</accession>
    <name>A0A9P6E2Y2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_246174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158032">
        <property type="protein sequence ID" value="KAF9521532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2Y2"/>
    <dbReference type="OrthoDB" id="3269273at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="437" mass="48006" checksum="C60769BDC45171A1" modified="2023-09-13" version="1">MNVEQLLDSTPAFSRSSFSAPFQPVTRPHGDHSYGAFGGSSAFSFSTSTSMPPSLSPGHMGTNGHLGSRDTEEGGNLHQSKRPRSHLSDSTNHSHSFNHQYTPPPVAGGIPPEIAKALADQANLSDARRLMFNSFHRACTKLPEKNDAMMRLLTYVLILQNTDKLDELAASLAKTSEKVETLYSATLKNFTVSKDLQVQIRTTARATLLEPDRRLFRDMFTDVQAAIESRSDDLSITSALQIAAHKRKIVTAIKGACNEAREFLRRLIVNSVMSAGPTRMSLDDFCARVLDKMGKDTQVVMSPELAGHLALMRAYTLGQLDRRGNVDSTPVPESDEGDDNDTTGSSSQSKSRSTKSQNQKEEEKFWVGFEKYMFNKVAEGGSKTGFNLIVRRIIEADRLRFPPLTTNTSLIDSALKPSSSSSSGQVATFEMVNDFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3I9</accession>
    <name>A0A9P6E3I9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157982">
        <property type="protein sequence ID" value="KAF9521845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3I9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="13020" checksum="7D787200A745C647" modified="2023-09-13" version="1">MSSAQIWTHLSATYAQKDMISVAEDLSVLFNLTFNERDPAPQITKFQYHYEGIHGNVHVAITDKLAAFMVLDRFPSKFSDKRVFILSTNLIANAGFTLDYVLDQLQQAYNVMIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3K0</accession>
    <name>A0A9P6E3K0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157976">
        <property type="protein sequence ID" value="KAF9521891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3K0"/>
    <dbReference type="OrthoDB" id="2834137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="80" mass="8700" checksum="B30E333B1E283238" modified="2023-09-13" version="1">MKHLMYYLNYAPDDRKFKYAGFLHAQSSGVEHYATNANGDPGSIWYEPDSGTNHFTVSAYTVSAGLAAHVAAAKWGTCAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E417</accession>
    <name>A0A9P6E417_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157961">
        <property type="protein sequence ID" value="KAF9522100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E417"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="332" mass="37374" checksum="B866BF161C95AC6C" modified="2023-09-13" version="1">MPMSSNYLSVPFGAPGSPLVIILSASLSLLACDLMENLVEDRRLVTEYKLSFPLFTYWIARISTYAYFVGAFAYYSNMNSIIGIEIIVWFVLVQRASTSLLLYFRVHALHRSNRYIQIFFVSYLLAIVASHIAITVAFITSKVKPSTICYCHNPCFVPFILLGFDSCIIIAFIQKVKAGYLPEEDRKQGWWLRNVFHPRSMHELASRLLQDNLVYYMMTVLLKTIWIGATATGNANFIIASIYLDTVCVCIITCKIYRDMRLGLPGLVHVTVEIVQGGGNITPLNFASPSGGRSTPSQLAKCGQFYVTLQYELKSPLTRARPDSRDQLVILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E424</accession>
    <name>A0A9P6E424_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157957">
        <property type="protein sequence ID" value="KAF9522173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E424"/>
    <dbReference type="OrthoDB" id="3242409at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="26551" checksum="1AFE8F3E29BD2C21" modified="2023-09-13" version="1">MASDSSLQLAATKAVRFSIQFASIALIYYDYTLTSMREVAYFWRHRSGLRLSTFLYFCCRYALVANVLYALALAGKVKYIRYVEFNLFELFAIQQYSCDTAYQICTALSVAGRFGILTVWGARTYAVFDKNKIVLICFAALGLTAIILACGLIYIGFVSLFSVGTIVLFNLKGTRGTVFERALNALTIPVSGLMTARFLIRLREWEYLSSSVNLSQSTMAGPIQFRQTETNTETSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4Z1</accession>
    <name>A0A9P6E4Z1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4Z1"/>
    <dbReference type="OrthoDB" id="3226064at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="49211" checksum="D50B9D1351F757B5" modified="2023-09-13" version="1">MNFTNLPPELIEAILVLCDPIVVSKVAQTCTTLRSLIYFSPDSMLWRELYLTQDLDDPRICVSHNGILKPTPIDWKKELKKVVRARTVVDDTSLGCLRRGELEDILQTLLGLTTCVRPWTTDEIFDLEELSKNLVWVAAKLRKGFLDRLVERSSDSGTDSHAQPKLTFAERQLAARLHTYFGLTKSDSMHRNIVKARAYVYLLRNYRPESDYGPYHPNGTVNWEHIRAVHHVVSTHVTDLDETTEFVYRIYLMSLPFTQVVAPHGFDFAKEEDWAGVTGLWSVSFCFCDHRELLQFNESSSTTIDATLFEAPDFREVFRSLNVNLVVARTEKDPDHPTRPIIYFYGQMVDPSTPTMTGKIQMTPDNQVRWHFVSGEQGNAIWSSEGIQIGGLHSAYGILGSWTTIFHDAEDPVGPFWMRKHNHTHGDNPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5M9</accession>
    <name>A0A9P6E5M9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_863794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5M9"/>
    <dbReference type="OrthoDB" id="5987198at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="66"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="44543" checksum="439BCC6468F47279" modified="2023-09-13" version="1">MSTASIPPTDGRKRRDLSSTIGGLTYNEKTWRTEYTWLLEQGYQLRERYAPEWKPSWVNGRKEKPYYEAADGLALTYGQVIDAIRVSDGRNVVLKRLSPALSPFEEDITRFLSSDELSQDRQNHCVPLLDVLHPPDEPTEILLVIPALRNFDSPRFDTIGEGVQCCRQLFEGIHFMHRHRVAHRDINFNNFMMDAPDMFPQGYHFNRINKLPDLRGDAPHFTRTQRPPRYYLIDFGLSRRYQEGEQALEPVVHGGDRSVPEFRANPQGLHDPFKTDIYYAGNLLRETITEGHKVLTWIAGYIGFEFLNPLIADMVQDDPNKRPTIDEVLKRFEDLAQSLSAYQLRSRPVSRRESVFKVVPNTIGHWKRKIWFTVSRTSAVPQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Q7</accession>
    <name>A0A9P6E5Q7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_71873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Q7"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="42587" checksum="40223E5956B465A5" modified="2023-09-13" version="1">MIYKRHSSSEEIYLSHLNHMVRRIIVDDTSDRIIYPQGIDWNNWNVVRPNYNTLNFGPPYNGTVHATADSTLLWFAFSGTSVEVNGYNDVSQSPDWTCTVDGTVIDGKSKMPFNNPLTFCQQPNLPDGPHNLTIEISKAKNRWFWFDHIQYTPSPNAITKDRAFIYQNDDQDLKYSTGWYPADSTTKTNQTGATVVLEFNGTAISGFSNLPAEFFESNSTPGSYSLDGNSSQTFDQSGHLNLVKASYNQRLFQSPTFAPGNHTLTVTYLGDTDHNPLFLDYLIVENYPTAYAAAVVANATDAKAAADAAAHAITAKAASIKDGKIAGAVIGGVALLGLLCLLYFSRHFISRAVRKLCGGCPRSATADPDHWEDSEKPPTYQAARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E649</accession>
    <name>A0A9P6E649_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_799500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E649"/>
    <dbReference type="OrthoDB" id="18302at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF15">
        <property type="entry name" value="SPORULATION PROTEIN RMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="218"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="442" mass="50194" checksum="C348CCDD188328C9" modified="2023-09-13" version="1">MPDQSKLKADPKVALDMKPRGANRSTKLAGKLKVLPEQPETLPVLGPKPPIRREKVVRDYAGSSGTTGDSDEGDIEENDESQEDEVEVYNQISLIPEGTARRDALKLTKKKAKSLPRVTAYATARSYRMSDLMKFFNARRNAYRTDPKMIDDVIYTPYVYDPPSTTHENRQSYMTSHPPTGDLLGLPELRENSTVENEDANRKRKISKFDTTAKEAEIFMFEYGTVVIWGMTEAQERRFLSSIKRFEVERLVPEDIEMEDLNYYYANYSRIYNDVITLRKGSSYMTKLSLSHALSQSVKISLFEELISSKIEETKDVPEVISETGKIGMPHKEIMQKIGQLFLLRTNINSVGSVLDSPEVFWSYPDLQPLYDAARSYLEIPQRINLLNTRVEVLQDMLQLLKESVSSKHAERLEQIVIALIAIEIVLGIITILVDLMAAPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E705</accession>
    <name>A0A9P6E705_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glutamate carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_862321</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E705"/>
    <dbReference type="OrthoDB" id="7832001at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="10">
        <location>
            <begin position="211"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="9">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="478" mass="51867" checksum="A238861993360860" modified="2023-09-13" version="1">MPAPDKFFKYIDDNADTFIKRLAAAVAIPSVSGDGTHRKDVVAMANWLNSELKQLGVDTKLVDLGKHVMDEQELDLPPAILGKLGNDPNKKTVLIYGHYDVQPASKSDGWDTDPFTLVVDEKNGRLIGRGSTDDKGPVLGWLNVIQYHHQNNIPLPVNLICCFEGMEESGSEGLDDLVRKESKKGGYFEGTDCICISDNYWLNTRTPALTYGLRGLAYYKVTVAGPGRDLHSGTFGRTVHEPMTDLISLLGTLVTPQGDILVPGVDDMVPPPDEDEKAIYAGLDYSIADIEGAAGGQIALSSDKVAVLMGRMRYPSLSIHGIEGAFYGAGGKTVIPAKVSGKFSIRLVPPQTPDNINPLVIDHLEKAFAKLGSKNKLNIEAAHGGKPWMADHRHWNYEAAKRATKIVYNQDPDLTREGGSIPVTLTFAEALGVNVLLLPMGRGDDGAHSTNEKIDKSNFIQGSKLLGSYLYELADVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E734</accession>
    <name>A0A9P6E734_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E734"/>
    <dbReference type="OrthoDB" id="3231000at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="9885" checksum="913CFDC0DC8879DC" modified="2023-09-13" version="1">MNLTKFSDDSKATVPQYLAVALPLTAVSIWVIMALHTETTKFDTEEERIDSTFLSRLVWPLRALRYLAKGLRQKVRTKRKIHVGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E854</accession>
    <name>A0A9P6E854_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_839063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E854"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040355190" evidence="1">
        <location>
            <begin position="16"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="229" mass="25466" checksum="E583AD65ACEDF928" modified="2023-09-13" version="1">MPAFAVAGLLALLKAMPLLYTPRWEDDCSRMKDSNIVGSIFSNNSSCPTLSSISLKVTIAFGIPSGSQVLQSQSDRVGPLSDFLALTLNALLTRADVSNVTSLSISVGPEDKDRHSFEPVNRPAVDHLLHFSNIEALKISHIHFGGLMQRFKNNIPFPHLRTFTFFNDHKNSRWGRKRTSGVPIKLDDGYEWQSCKGRQSENLELLSLGEDINELDARMLDELSGLVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E882</accession>
    <name>A0A9P6E882_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_861555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E882"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="34080" checksum="98E4023B858220A9" modified="2023-09-13" version="1">MSISALYSQSFPPKSKFTVDDIPDLTGRIVIVTGANVGVGKETAKALLSHNAKVYLAARNKEKAEAAINELKELTGREGIFLKLDLSNLASVKAAAEEFLSKENELHILFNNAGVMVPPHEQLTTQGYDLQFGTNVLGHFYFTTLLLPALIAGKNTSPDKKSRVVTTSSGAAYLSSGINFDALVDGHQRKKTSVETLYKDSKLGNLLFANELAKRYEHQGIISTSVNPGNLKSDLQRHVSFIQSILIKPLLHPVAFGALTQLWAGTSPEGLELNGQFLIPWARRTTDLPSAASNAKLAADLWTWCEEQVAKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8J5</accession>
    <name>A0A9P6E8J5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Urea transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_861182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8J5"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1730.10:FF:000006">
        <property type="entry name" value="Urea active transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF2">
        <property type="entry name" value="SOLUTE SYMPORTER FAMILY TRANSPORTER (AFU_ORTHOLOGUE AFUA_6G03200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="576"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="610"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="664" mass="70293" checksum="29B61B2DC324B7F9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9G2</accession>
    <name>A0A9P6E9G2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9G2"/>
    <dbReference type="OrthoDB" id="2756178at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="114"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="714" mass="81934" checksum="DFE787B2D4799321" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9L7</accession>
    <name>A0A9P6E9L7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_860260</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9L7"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="19"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="100"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9525081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="142" mass="14976" checksum="190A371355E0CC95" modified="2023-09-13" version="1">MSGKGKSGKSGGKAADSGEATKSQSRSAKAGLQFPVGRVHRLLKKGNYATRIGAGAPVYLAAVLEYLAAEILELAGNAARDNKKQRIVPRHLQLAIRNDEELQKLLGNVVISQGGVVPHIAPELLPTKSGKSKKDEGISQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9U6</accession>
    <name>A0A9P6E9U6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_562195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9U6"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="133"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="33899" checksum="FC79E57AC689DDB8" modified="2023-09-13" version="1">MTQLRLTNCAICSDGPIALDQFLFFSCGHKACKKCVGNNDFRKNPLCHECRQPKGAPHKVYLDFEEVVEEQRQQIIDGLNKIDMVSPGESIDKAGKKIRRFYKKCDGDPEACRPLLEAANDLQERVAPMFAKHATMKEENESLLARLHELEAMAETNKQNAKLAKILVDKEKDEAQRHYDRAQRYLSRIERKEDEILKLTQQLEEKNNAYRLLQKKTKGVDSTARKRIRLVSQPQEEDDSLVIEGKPEITPPKRIKRSHPPTVLQDANTDKHERRLKRRRRGASSNSKAREDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA75</accession>
    <name>A0A9P6EA75_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA75"/>
    <dbReference type="OrthoDB" id="5525680at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14517" checksum="39B8B815E904DC90" modified="2023-09-13" version="1">MMIRTIIRPHLVENAGSTARDYCMLERNLLSHIKLALLLTLLAASLLLSARLVPPGEQDHESPGSIALASIESVTAIACMVAGCLEYYWGYRDIKNSRAFLIAVKPHLSIMSGVATVVFVTCIYFLVQDEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAI0</accession>
    <name>A0A9P6EAI0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_859575</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAI0"/>
    <dbReference type="OrthoDB" id="6512771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01422">
        <property type="entry name" value="zf-NF-X1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="R3H" evidence="11">
        <location>
            <begin position="874"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="969"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="972"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1015"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1076" mass="116290" checksum="A787D7912FCEC5DA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAM4</accession>
    <name>A0A9P6EAM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAM4"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="12"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="445" mass="50153" checksum="5044E0BD19736678" modified="2023-09-13" version="1">MADGTGSEGKSRTLVLCFDGTSNEYDSENTNVVKLYALLKKDNFDEQLCYYQAGIGTYFEPGAVSPLLRVGATLLDYAFAAFLDWHVLDGYKFLMQNYRVGDKICIFGFSRGAYTARALGGLLYKVGLLPRDNFSQVSFAYKMYQREDKEGLRLCSGFKQTYCRSVKIDFMGVWDTVASVGIISGRTLPFTNSNSSIKTFRHALSLDEHRAKFRPNNYHRIPRSKKPSKNDPDHTTPSEMHVQIGKTRNSTTKDNGVVSPVPDEPGEFAKQTGKSAGTALDEAGLPDDVQEVWFVGCHSDVGGGAVSNDTPHSLANISLRWMVREAIKADCGIQFDDDALIRASLDLDPEPSQTEIDMDDQDAMAPIHDELKKHKIWWLLELIPLHFQWQNEDGEWKKDWSCHFGRGRDIQTSTPRFHITVEKRMKAMGYVPKAAWKKGTELYMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAR8</accession>
    <name>A0A9P6EAR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_859243</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAR8"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF14">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="36"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="523" mass="57716" checksum="087149BDA702CA48" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAX2</accession>
    <name>A0A9P6EAX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PapD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_859051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAX2"/>
    <dbReference type="OrthoDB" id="264603at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="MSP" evidence="7">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9525756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="295" mass="32828" checksum="A7A39D46565A4A19" modified="2023-09-13" version="1">MIVYEEPLVDKPSLTMKIQNKSSRHVVFRIKTTAPKLYTTKPHQGMILPGESMAILVTVVGWKQEPQLAGLRIKDKFLIQTADVPQGQEQDTVQDVMTKVVQESEQLVKQRKLKVAYLPPEPRAHTPYESEVEDVHHLDRADVAVGGSGVLVDHYVMQPSPPQPINQESSASSQSSPDESLGGPPPEDPLQRSDYHEAAKPDFIQSLPNTQNPLVDTSMDDSMLDQSELRQRRPTENYDHASQSAPSEYSNTPSQISREISISERIPPFLQQGVPLWTVLASVAATYTATRFLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB72</accession>
    <name>A0A9P6EB72_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_896727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB72"/>
    <dbReference type="OrthoDB" id="3056080at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="79"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="30728" checksum="1B2AF11171B9E7A3" modified="2023-09-13" version="1" fragment="single">YVNEQFDQLYERIAALELRLSEVSVPQVPTAPPAPTIAAITSKPSRRARKKASAPVSAPPVSIPAHPPLSGSFPKEDPHLVGKGGRGLKQIHDLSGAHIRAFEVKDGSVGARHVSIRGSDSQVGDALVVLGKRLARRRVRAPQQKSTKGSSRVKPSVPPLATSGLVGPGAAKSAAPLPATQAPPLLKSTTPAWAHPLASSTPVAHSTPPPAPSIVMQTAAPPSLVPTPGARSTARTPRTMPNTPIVPTVAMPTTDSTPGPSYPSSPMNIDALMARHQGTLPASSTSDVVQRSPQQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBC4</accession>
    <name>A0A9P6EBC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_837839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBC4"/>
    <dbReference type="OrthoDB" id="3439489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="152" mass="17164" checksum="D352060B66B8D7E1" modified="2023-09-13" version="1">MSTLNSGPYFIKSAGAEKFIGRARVEYRSLQPKRILLRTTDGSEPPVIFKFELKKQGDTFEIATRGGAIASIDDKLYAVLMPEEPIQQWIIKDIPQQGQNKYLITTNQEDRGWGSPKDDPGAQIELVKLVHSIPRPLQLPHNQIWEIVPVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBI8</accession>
    <name>A0A9P6EBI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-RNA processing PIH1/Nop17-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_870609</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBI8"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="3">
        <location>
            <begin position="45"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="401" mass="42889" checksum="4F1778687338D7EF" modified="2023-09-13" version="1">MATVPVSLSPRPGFCVKSTTLGPGVIPPPPPSAASATKPKATHPNFLEPTAAANAPIPVQKGTKVFVNIAWDANVPPPPEGNEDAIQRAMQGEDDQLNPDAWYVPVIVSNARQDKDKAGSPSIVFDCIYNSSVKARTIRDPDFKIFLIELALQRIEVQYGLSLSRSIGTPNIASKGQLVARTVHIPAALLATTTTTKKEKEKATSTENAVRITTGSSIHSAAPTSTPLIQEISTKSSSGKSSEVSLPGLRGILTTSKKTSASIPPASASAHARAQPRIPNTVTTSPLEWLWTKQEDSGKLLIQVKVPNLTTPLVHASTLDIEPRRIILSIPPFPILDIDASISDAEIAARMSRVYASSPESQNERQEATTRTLLLKRQKAFDVDGADARWKIGTGVVEIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECN0</accession>
    <name>A0A9P6ECN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS13m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_876641</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECN0"/>
    <dbReference type="OrthoDB" id="525520at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000004">
        <property type="entry name" value="Small subunit ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="168" mass="18981" checksum="ADB1ADBB4DFEFBD5" modified="2023-09-13" version="1">MVHVLGINLPDGHVVKFALTKIYGVGPHIANRLCARLQVHDKCKVKDLSPFQVTSLASFLSSPTTSPPLPRLPLASPDFTPPPSTISTQELQARFNEQLKQRTIKSTDPLRNLKIESELRREIRENIAHQRMIGSYVGRRHAMHLPVRGQNTQNNAKTARKLNRLERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECP0</accession>
    <name>A0A9P6ECP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Snf7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_870210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECP0"/>
    <dbReference type="OrthoDB" id="10250120at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF96">
        <property type="entry name" value="BCDNA.GH08385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="486" mass="52557" checksum="429D9DCCB467EA24" modified="2023-09-13" version="1">MSKSTPPTPSTPFASSSSIASNLAPFSTTSTSRLQALYSDFSRQKQSNPASYHANVEWWRKALESLVISGSQDIDFSVSTLEDSTPPKSDRLILHAGKPLVERVKIPKVGKPLSLGAVLSDLRSSKIALPLSEFLNANASIYDPGWLPGRIASFVVGKPLWWALEHMGIVGEEGILGSFSSSPASGRNSQSTSWHGDYVLVSLVERAADEVEDMLAKKMASKTDALFTKESFRDAFGAAAGGDDVLREADATVLVKYLERDRGVVVVDKEIIKFVESAASAEERTITAVDRGILELKTAIRNLDAQIESLQSKVDECTKKATLALQQKRKPAALGYIRSRKLLEGVLEKRLGSLSTLEATFISVETAAGDIEIMKSYESSTTTLRNILSHPSLERGKIDETMEALAEANTNAKEVDDIIRIGGDVALGIDDAVDDDELEEEWKAMVKEIEVDNMAKTLAQGGRIPEHESSKDEAVTEGSAGVLVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDK9</accession>
    <name>A0A9P6EDK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chaps family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_793307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDK9"/>
    <dbReference type="OrthoDB" id="434695at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034044">
        <property type="term" value="C:exomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000149">
        <property type="entry name" value="Clathrin-coated vesiclec protein (Bud7)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015374">
        <property type="entry name" value="ChAPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09295">
        <property type="entry name" value="ChAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="776" mass="86627" checksum="CCF3BBBB8B036174" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE02</accession>
    <name>A0A9P6EE02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_856618</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE02"/>
    <dbReference type="OrthoDB" id="17725at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="314"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="548"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9527245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="666" mass="73677" checksum="B52CB283BB58E2DB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE39</accession>
    <name>A0A9P6EE39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_793566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE39"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="399" mass="43156" checksum="99E13AA7A1964A48" modified="2023-09-13" version="1">MREIVIVGGGIIGCTTAYYITRHKEFLEGAIKVTLLEASNRGPAQGASGKAGGLVARWAYPKGIVDLSFDEHVKLANEHNGEDRWGWRYVNCGSWEGRGTTRKNPGKSLEKEQGLPGGQKPLKGKSASSKRKLPDDLQWLKEESTDSYTPMARHGNTAQVHPYLFTMSMFDLAKEAGLQYICGQVTKILRSSEAVTGVEYFDPYTNDIQTLSASQVILTAGAWSPTLLPSLKLTATRAHSVTIRPIEETSISPYVVFTEFKDSSSASGPEIYARPGNEVYACGPGDDLALPATVDDVQVDESACDLIYKQVSSISDELRDGKIEKRQACYLPTVNSNRGGGPIIGEAKTVAKGLFIGTGHTCWGISNGPGTAKALSELVLEGEIKCADLKRFDPALYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EER5</accession>
    <name>A0A9P6EER5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex protein EXO70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_768212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bud</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Bud neck</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EXO70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EER5"/>
    <dbReference type="OrthoDB" id="1922221at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.170">
        <property type="entry name" value="Exocyst complex component Exo70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004140">
        <property type="entry name" value="Exo70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046364">
        <property type="entry name" value="Exo70_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542:SF41">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542">
        <property type="entry name" value="EXOCYST COMPLEX PROTEIN EXO70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03081">
        <property type="entry name" value="Exo70_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex subunit Exo70 C-terminal" evidence="5">
        <location>
            <begin position="242"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="608" mass="67892" checksum="3C0D99E84BEDC17C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF01</accession>
    <name>A0A9P6EF01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_894820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF01"/>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="130"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="274" mass="30228" checksum="5D49EE1BE6E7C0BC" modified="2023-09-13" version="1">MAGLLHPPKAKPGSGRKPAAAPFGASKPTKTKRNPLFEASPKNFGIGQDIRPQTDLTRFVKWPEYVRLQRQKVILHQRLKVPPAIAQFSHTLDKNTATQLFKLLNKYRPETKQEKKTRLEAAAASAAADKEKAKDKKPIYVKFGLNHIVALIEAKKAALVVIAHDVDPIELVVFLPALCRKMGVPYVIVKGKARLGTVVHKKTAAVLALQEVKSEDNRDLSTIVSAAKANFTDKYDEQRRQWGGGIRGNKSTQMLRKRAKAAGQNHTAAALGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF54</accession>
    <name>A0A9P6EF54_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF54"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="61" mass="7178" checksum="B8CD3FCCE9E11D06" modified="2023-09-13" version="1">MPSPAYSMHPTREGQNILPIPTPSFQQVAYQQPRSQQFVPYYDQQGIYSDRPYTNDDEERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFF8</accession>
    <name>A0A9P6EFF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase I-specific transcription initiation factor RRN3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFF8"/>
    <dbReference type="OrthoDB" id="26970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001042">
        <property type="term" value="F:RNA polymerase I core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007991">
        <property type="entry name" value="RNA_pol_I_trans_ini_fac_RRN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790:SF0">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IA RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05327">
        <property type="entry name" value="RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="821"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="483"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="823"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="899" mass="99534" checksum="4056D25352AA7831" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGB0</accession>
    <name>A0A9P6EGB0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 small nucleolar RNA-associated protein 6-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_766554</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGB0"/>
    <dbReference type="OrthoDB" id="28112at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="209" mass="24422" checksum="99844EDFFCF41D5D" modified="2023-09-13" version="1">MERVHFEQERMVEELKDLVDRGLFTEKETKQILKKRTHYETLLIRRVAKKSDFLRYAAYEMGLEALRRKRVHRIEADGPRTVSDYGMVKRQFEIFERALVKFKSDVGIWVQYIQVAKREGATERVGRVLARAVQTHPGEEQLWVMSAQWEMQGGSVTGARGILMRGIRMNGTSAEVWREWVRMERWAGVDGVVDEVERQARMAVPGIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHC1</accession>
    <name>A0A9P6EHC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHC1"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008142">
        <property type="term" value="F:oxysterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF184">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="44467" checksum="904B9CD212CAFB1C" modified="2023-09-13" version="1">MSTEEVGQAVPASQRGSWSSFLKSIASFSGDLSSLTAPPFILSPISLTEFPAYWCERPEYFAAIADAKPGYERSIAVLRWFISTLKDQYTSRNDEMGSEKKPLNPVLGETFFGTWPDKNGRGVTELLVEQVSHHPPITAFVIENKSKGLRLTGHNAQKTSFSAGSIIVKQIGHAVLTVQPKDTSLPVETFLITLPKLRIDGLWYGSPYIELTDFSHIIGGGYATSIEFKGKGYFSGRSHSFKATSIPIPGQGGAGPKEVVIDGTWHESSKYTKGGSGSFHDVHEHKEVVKPLEWTEELGEYETKQLWKLVAKGIREGDFELASREKSRIENEQRQKRKDETAAGSKWELRFFEKQDSDPTYEQLARIAKLTPPTEEKYAFKGNWPSNFATIVAPPAPSGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHJ6</accession>
    <name>A0A9P6EHJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHJ6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="17055" checksum="D59BDE5A3285C445" modified="2023-09-13" version="1">MDFMKDVSLPALEFLDCQTEEPAIMNHLTSLIHRSSCSLKSLVLEFTLSSSSRDGQAIKLLQLMPMLTHLEWRSVLGTAFFQRFADAAFWNEGSNDTFLPHLQSLIYKARRKFPFGLILKAASLSSPKPGQARRPLNNLQFFFTGDGTSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI61</accession>
    <name>A0A9P6EI61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) endonuclease 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_852258</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI61"/>
    <dbReference type="OrthoDB" id="391817at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09088">
        <property type="entry name" value="Ape2-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF4">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="14">
        <location>
            <begin position="567"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="377"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="588"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="532"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="11">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9529515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="638" mass="70596" checksum="86AC954E3F1E6E7F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJB5</accession>
    <name>A0A9P6EJB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJB5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="12594" checksum="A5B6CC8CFA727C4B" modified="2023-09-13" version="1">MSCRVKRRVREPERSRPRAHRQNLLGLDLRPSTIFYWYVCILETLLIVFLRGYYVSETKLTFVATAQSADTLHRRDLAATDLAFRANKIAHLRRMINPFFIRSQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJI8</accession>
    <name>A0A9P6EJI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heme oxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_892831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJI8"/>
    <dbReference type="OrthoDB" id="37730at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19357">
        <property type="entry name" value="TenA_E_At3g16990-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053261">
        <property type="entry name" value="Polyketide-peptide_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41813">
        <property type="entry name" value="REGULATOR PAB1642, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11955)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41813:SF2">
        <property type="entry name" value="REGULATOR PAB1642, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11955)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="25540" checksum="2734FAE7980B353E" modified="2023-09-13" version="1">MALTLTEHLSSTSAQNKLYIEATQHEFLTLAGQGKLPLDRLALRLSQDRIYAAHAYPRFIGALITRIPFKETDEICGDVEKKNQEILKALTSCLTNIVQEVDFFKQTANMFGMYMDAWEERKEGLVFLWAMEKVYFDAWTYVRKALQTCDAKSESSPAVKKFATNWSSPEFDSFVGSLADMINDIKPGTAEWTRGEAVWQRVLELEVTFWPESGEEISMRKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJS6</accession>
    <name>A0A9P6EJS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S19-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_850745</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJS6"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="152" mass="17367" checksum="CF3E2279A8B3D53F" modified="2023-09-13" version="1">MAEITDPQVAADLKKRRTFRTFSFRGVELDKLLDLSNEDFVELVHARARRRFQRGLKRRPMGLIKKLRKAKKEAPPNEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLAEFSCSYRPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKA6</accession>
    <name>A0A9P6EKA6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_851128</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKA6"/>
    <dbReference type="OrthoDB" id="425925at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019459">
        <property type="entry name" value="GRAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921">
        <property type="entry name" value="MYOSIN HEAVY CHAIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921:SF2">
        <property type="entry name" value="THYROID RECEPTOR-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10375">
        <property type="entry name" value="GRAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="6">
        <location>
            <begin position="330"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="378"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="58"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="224"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="460"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="57010" checksum="DE96F92B9808A684" modified="2023-09-13" version="1">MTSAHKASGSLSESTDNKMARSSLDSQQSGSDNGIAPKQNGHASTNGVDMSDGSGDPVERLQRELERTREEKETLATQYRNLLAKLTQMRTTLGNKLQQDAEELDRREQLIQQLTAERDDFSATINTLKAELITSHEEAERVSSQLDSMRTRVLQDTADESLQRERELRDAQMELERCRMEREEWERSALREQTVSEELRTTVEEMRRDFELESVARANDMVLLEQEREKSENLQSVLQDFQAAKDHELKAAVQGFEKQLLDVTQSLAEYKHRALTAEMELEESRININKTQELEKEVKEKRMLIEKLRHETVIINEHLMEALRRLRRNSSENNVDRRLVTNVLLSFLTTPRGDTKRFEMLSLLSSILSWTDQDREKAGLQRTGPHELTSPSGFWGRSVSTGSPGKPEIEKTDETESFSRLWVEFLLTEANSGGEAGNSTSSLPSLPRSSTSTLPTSPTGGSYPNSPFRNTRRLSSLSNMGMASSPNLHAPSPSRKGKDKEAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKE9</accession>
    <name>A0A9P6EKE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">VHS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_904522</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in the regulation of membrane traffic through the trans-Golgi network.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKE9"/>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14235">
        <property type="entry name" value="GAT_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16998">
        <property type="entry name" value="VHS_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000008">
        <property type="entry name" value="VHS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052653">
        <property type="entry name" value="ARF-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="8">
        <location>
            <begin position="23"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="9">
        <location>
            <begin position="186"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="450"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="502"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="530"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="583" mass="62254" checksum="1BD55EDB5FC2B8C2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELJ8</accession>
    <name>A0A9P6ELJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="10">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_849278</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="10"/>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELJ8"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="18">
        <location>
            <begin position="49"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="489"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9531073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="542" mass="59862" checksum="5C88D42EADE19CCA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELY9</accession>
    <name>A0A9P6ELY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELY9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="20437" checksum="1CCED37FEA6C263D" modified="2023-09-13" version="1">MRSKAAAVEEAEVIDLASDEESEASQEPKKTRSKKAKATTEPAVIALNAIPIYDVPALRLMVRTTEIEEEKAIEEQRKANILAQKELEKEKLATLDRIQEMAPVLADLNGTVDRLNMAFQRLEADSAKMGVDVPTYVKSMMSTVNMGMQMMPGGFPMQGMWGGMGGMMHGGTMHGGGGGMHGGVVLLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM03</accession>
    <name>A0A9P6EM03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_101458</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM03"/>
    <dbReference type="OrthoDB" id="2432613at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045328">
        <property type="entry name" value="Kre9/Knh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28154">
        <property type="entry name" value="CELL WALL SYNTHESIS PROTEIN KNH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28154:SF1">
        <property type="entry name" value="CELL WALL SYNTHESIS PROTEIN KNH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040237756" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="27390" checksum="F04B39E5BB3F6144" modified="2023-09-13" version="1">MYLTNLKLFLVILYLNWAPLVSAGLYVISPSDGSECVANQPCTVTWLDDGRQPLLTAVGVSTIGLYTGRQRLVQSITPVDVSTVHSLTFQPNPAAGPNDGGYYIAIQSTEFKTNNSMPYTSFSPFFRLSGMTGSFDSPLPAATSPIPIPPSLTQIPSSSATSTITVGGPSHATPQPPITTAPFTQSPSVSPSDNPTVSSASSQGTSTLTFPTSFRMTTSVLSSTTSSSANAASSSSSSSAGARTVAQLSTLSLVFAVSMILAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMH2</accession>
    <name>A0A9P6EMH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMH2"/>
    <dbReference type="OrthoDB" id="2898509at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="34144" checksum="59934599456A0CFD" modified="2023-09-13" version="1">MVSLASIRASNAAVTHRTRPLAVFVGGTSGIGEGMARTFGRHTNGNADIIIVGRNKAAADTILSSLPTPDPASGSPPVTREFIQCDATLMKNVNAATQDILFKYPKINYLVVSTGIMTLAGRDKTVEGIDKKLAVHYYARWKFIHDLLPLVSKAKSEDETGSVMSVMAASGGGAIDLNDLGLKKTYSLQNAALAAPTYNDLMMESFSERYPSLALIHSIPGIVRSGLAANSPSAVFRWSNFLLNTLFRPFSVSPEECAEYMWHGIYATASKPGAWRTDTHGGDLGKKRYYGDEEQRTKLWEHTSEEISAALKQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW2</accession>
    <name>A0A9P6EMW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low temperature viability protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_760668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW2"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04180">
        <property type="entry name" value="LTV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="545" mass="61559" checksum="C8DA1BC32DA78F05" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMZ8</accession>
    <name>A0A9P6EMZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ADP-ribosylation factor 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_760847</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMZ8"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000286">
        <property type="entry name" value="ADP-ribosylation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20776" checksum="C59E30681A18894D" modified="2023-09-13" version="1">MGANLSKAMSKIFGNKEMRLLMLGLDAAGKTTILYKLKLNQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLVFVVDSQDRERIDEAKQELHRILSDREMKDCLLLVFANKQDLPGAMSPAEVTEKLGLHRMRDRSWYVHPSCATTGEGLFEGLQWLSQNVKKRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENB8</accession>
    <name>A0A9P6ENB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sfi1 spindle body protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENB8"/>
    <dbReference type="OrthoDB" id="1933281at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013665">
        <property type="entry name" value="Sfi1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08457">
        <property type="entry name" value="Sfi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sfi1 spindle body" evidence="2">
        <location>
            <begin position="315"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1054" mass="123272" checksum="0098076A82BBA46C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENS5</accession>
    <name>A0A9P6ENS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_845927</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the polysaccharide monooxygenase AA13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENS5"/>
    <dbReference type="OrthoDB" id="120613at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="8">
        <location>
            <begin position="38"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="22728" checksum="9084123BF0284BB8" modified="2023-09-13" version="1">MPIKCLTQRQRGLADLPHMFSLQTLTCILPFVGIALGHGLITTPKPRAPGTATQAACGTGAYNTLKNDLTTPVEYALQAADSGYKADACKLYFCKGYQFEDNKSNVARFSTGQVVPFQINLRVRHTGYANVSVVDLATQTTIGQPLVNWPVYASPTVVANETTFNVTVPDLGTKCITAGACAIQWWWFGSSVKQTYESCVDFVTVPPPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENZ8</accession>
    <name>A0A9P6ENZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_847267</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENZ8"/>
    <dbReference type="OrthoDB" id="941679at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9532710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="16529" checksum="726100834EC9E2DC" modified="2023-09-13" version="1">MAKVYDVRGYLGSVGVTTPVSTVHTWVNIRANPALCGADFVGANAHAFYDGGRTSGQAGDFVFKTVVPALKAACPGKKVYITESGWPSRGGNNGVAVPSVADEQNALLNLNCANRDDTSVSVYAFEYDDQLWKGNDNERSFGIFGKINLGTAFAPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP10</accession>
    <name>A0A9P6EP10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metal homeostatis protein bsd2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_846923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP10"/>
    <dbReference type="OrthoDB" id="10003116at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031398">
        <property type="term" value="P:positive regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="48021" checksum="6C9070AD5DF127FA" modified="2023-09-13" version="1">MPAGYAPLPNPRSAPDAEREMEDAFDLNDEDDQADTEETPLTRRTAEHPQPETSSTRQETTALSGGAYDFEREYDLPPPGSPPRPSARALPNEIGNSNGLLPTAPVDRPQPQRSFFRRIMGNIIPSQYQPVATDSHSTRLTGGGTDNDGVFANVTAKPAPARVVRSENGDIQIMPEESQKELPPTYQEAQADAVPPYWETTVHAPGSLDPNADLIIEDLPTGSFLIFCVNVFISFFFQFVGFLLTYLLHTSHAAKFGSRAGLGLTLIQYGFASRSINLGEDQVEGTGAQGSENGWTPKPVPSDYNSIPGSSSTTSPSSTSNAEYMMSSSSRDWLSFLFMTLGWFLLLSSVLGFWKVKRWEKSVRPTQPDPVAPEDIERDRHVRRRLEDVFGFAVADPPGQAREHLFQAPGSVQVQMHRSQRDDERLARDLRAAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP38</accession>
    <name>A0A9P6EP38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_470577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP38"/>
    <dbReference type="OrthoDB" id="3270368at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="628"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1157" mass="128711" checksum="E962EF7CFE93ECA0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPA7</accession>
    <name>A0A9P6EPA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPA7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="27797" checksum="5D23F20E6142E1A9" modified="2023-09-13" version="1">MKYESAEIRTTCRYKRSVNTTLFSPAGLTPTHLHITSTLALHAQVIYTQHFNNLNQSLSQINIMVQISTLFIFVTLAITPLLAAPLSVQDIQSREPDQASENMFLAAREPRRFGAGGRGGRRFGRKAAAPSSEEAREFDDNLETREARYAGGHAGNGGRKHPRELDFEEVEAREPGRGGRGFGGGRGRRFGRKAAPAASEEARDLDGSLELVEARSRHYTKGGGALGHNHRRELDFEEVEAREPRRGGCPCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPU4</accession>
    <name>A0A9P6EPU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfide:quinone oxidoreductase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_846636</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SQRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPU4"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070224">
        <property type="term" value="F:sulfide:quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070221">
        <property type="term" value="P:sulfide oxidation, using sulfide:quinone oxidoreductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000034">
        <property type="entry name" value="sulfide:quinone oxidoreductase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632:SF2">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="442" mass="48468" checksum="FA9A422A881E121F" modified="2023-09-13" version="1">MLYKRILKGASEVHRSSRSFATVSESKYKILVIGGGTSGLSVARQVYNRFKLAGKPLNDGDIAIVDAAKDHYYQPGWTLVGSGLRPKGDFAQPLASLVPKHIDHIPENVKIFSPDSSTVTTSSGRNISYDTLVVAAGLQINFGAIKGLSEALTDPKSGVSTIYSYDTCDKTWSDIENLKKGPAIFTQPSGIIKCAGAPQKIMWMAWDRFRRTNRQDIKLDFYTGMPTMFSVKKYSDALNTLRKERGVGGFFGYDLVSIDSASQKATFKKSSDGTTVDVDYSLLHATPPMGPLDVFKGSPIADTTGWVPVDKDTLQHTKPEYSNVFAIGDCSSLPTSKTAAAVTAQAPVLVENLFSLISTGKIAGAKYDGYTSCPLLTGYGELMLAEFKYGLEPKESFSAFFDQSKSNRFFYHLKKDLFPAAYWKYMVNGEWFGAKGLSRPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ78</accession>
    <name>A0A9P6EQ78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_805086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ78"/>
    <dbReference type="OrthoDB" id="2020419at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="778" mass="86831" checksum="930C8C325FE1DFD6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQI8</accession>
    <name>A0A9P6EQI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_903083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQI8"/>
    <dbReference type="OrthoDB" id="3238347at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="93" mass="9863" checksum="4AD986080A780656" modified="2023-09-13" version="1">MGKSAKTHKKLPKKTRSITAPNHPISTAPSNAKAQSAQERSRIKSKANSSVKTSKPDPSKGLLGGADYVSILMDGRRKARAEAQKAPQDPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER04</accession>
    <name>A0A9P6ER04_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER04"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="449" mass="50964" checksum="9B646236D8CCDA34" modified="2023-09-13" version="1">MVELPPELVELIVDFCPYEIPLWGTPSIEDKQVLLACTTVSRSFYHVARRRLFSTFVIRNFESSSHNLQSLYELVRRPDFLALVHTLKLQIVEGRFWPLGSNDPHVQRVLSAFNQPDSTVQHLCLACPFHTTFNDNFGQLAQKELLVMVSRIHSLTIRGMASPIAFLANAPLLMNIQLLDAPLEVNNAGLGFLLSAHIKVAVFRGGVDQQLDALCQGYRDRHQDLPSFESVRLETSREYNGYNQTTLLQESHDTLYLLEIMPYARGVTPNIARFNIGGLKKLQTLRVIFDVVVTHFSLSNFLILHSLAGVSESPTAPSFVTNIEVLVLCQGTMPWPTVNNAEILDEHFPRDRFGHLNPQNLVKYHPALRSLDFIYDLSQVVFHTRQTRTIEEDESCLEQILRPTLERAILGSVRAEEQRQANISVSPYMSVRVSCVCPSPWQPYKNSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER53</accession>
    <name>A0A9P6ER53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA splicing factor PRP21 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_845177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER53"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01800">
        <property type="entry name" value="Ubl_SF3a120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000002">
        <property type="entry name" value="Splicing factor 3A subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045146">
        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035563">
        <property type="entry name" value="SF3As1_ubi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="47"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="152"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="724"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="332"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9533382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="780" mass="85672" checksum="3217CB41A6DCFB7C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER82</accession>
    <name>A0A9P6ER82_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_472504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER82"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09880">
        <property type="entry name" value="PIN_Smg5-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF0">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN EST1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="813"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="983"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1214" mass="133970" checksum="06F49B6AE65FD30B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA3</accession>
    <name>A0A9P6ERA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Laccase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_409339</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA3"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000045">
        <property type="entry name" value="Laccase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="54"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="167"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="370"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9533796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="526" mass="57521" checksum="77A21C52BE13AED0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERS6</accession>
    <name>A0A9P6ERS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphomethylpyrimidine kinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_783427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERS6"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19367">
        <property type="entry name" value="TenA_C_ScTHI20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858:SF17">
        <property type="entry name" value="HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PHOSPHOMETHYLPYRIMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="1">
        <location>
            <begin position="350"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="572" mass="63157" checksum="5FD2A24C1646F575" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES44</accession>
    <name>A0A9P6ES44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sister chromatid cohesion protein Dcc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_843924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES44"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="42755" checksum="6E3CE746B90B7906" modified="2023-09-13" version="1">MVECELSFSHASFDEAGSYKLVELTPDLTTLFENALKDDIDVNLTIKGHSNNDAVLCTDKKTFSMRSVSLSNTILVVTPVPDEKAVDFADGAVIIRDQLNEIIELVPVVPKLHKLSALIRERQYDESQEDEAEPEDDDSVKRFTYQDALEQIQSSEEELKNGLKERKILIVHDELRPIAPAYLTRLLELILNSLVSLSMKHDSASTERLLAELANEHEIPRAVSEQVMRWFGEIDTNSGKWTMNVNGIVKEVGLGILGDYRHEPIEKNVLLAKWKSQVGDTFESSVSLDLLAGNYIQSEVLGSDEIHLKYFPAFALPVDPAARFSELFLTHSKWKTDEITPFLSDIAVNSKERDKLLLKYCRAVTDAGVVRYSARAQYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES82</accession>
    <name>A0A9P6ES82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_423061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES82"/>
    <dbReference type="OrthoDB" id="2637047at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="131" mass="14702" checksum="52CEC587B15D805F" modified="2023-09-13" version="1">MSYWVGKVTEIRVTKDDFAWLLIQWYFRKADVNDYSVTINGDPGTSQKKAIDVLINQLGDSEVVKSDSWDVVSPMTVKEVVSLIQLPDNATVVLKPSKGVLFSRFDATVNASERKMNIQTSYKGFEGFSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESE6</accession>
    <name>A0A9P6ESE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_781944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESE6"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040419450" description="Thaumatin-like protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="19504" checksum="3D8C0846A3139C48" modified="2023-09-13" version="1">MFKPVVVTGLFSAACFVAADHTFNFHNQCGYTINPKIVNVNCGYSPRCKTPGSGGVPNPAISYNGPQPQSLGPNQSTTLHINRQWNGRIFHQSGSCGAKGESCTLGEFNLDTGNQFTAQAFDISNIQGFTIGLKIAITGGDSVTCTNVNCGCKNAYPPGDTSGCGTDLPVRGGSPGDKTWTVTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESH4</accession>
    <name>A0A9P6ESH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_843861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESH4"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="33"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="792" mass="87257" checksum="209C3B4FBB40B47E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESQ0</accession>
    <name>A0A9P6ESQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_841772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESQ0"/>
    <dbReference type="OrthoDB" id="203796at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="637" mass="71105" checksum="8E9D4658875F07EB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET21</accession>
    <name>A0A9P6ET21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_872667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET21"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="35970" checksum="419E15D4069031EF" modified="2023-09-13" version="1">MSLATRRVGNDKVSEIGFGAARLSPRGVESASDEDRLQFLDALFEEGCTFWDTADRYGDSEILLGKWFKQSGKRDQIFLATKFGATADGLNNSPEYMKAQIDNSLIRLGTDRIDLYSWSIKLLIVDKFKRVDKNIPIEKTIRAMIRYLGLSEVSAKTLRRAHLVDPIAAVQVEYSPFALDIEEIGLLQACRQLGVTVVAYSPLGSGILTGAYKKHSDLPDNDIKRRVPKYSQENFPKVLEKHNATPSQVTLAWLLAQGQDIIPIPGTKNVKYLKENVGAVRVKLNLEEIAAVRKIVEMANLGGFARYPPEYSDNLYADTVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETA5</accession>
    <name>A0A9P6ETA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_889448</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETA5"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF12">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="27853" checksum="F48A4AD0F61361F1" modified="2023-09-13" version="1">MRSVPARRDPKFILQNALDFSQRDLHKTFQEWGKKYNSGIVHATAICKHFVAVNDLDIAEELFEHGATVYNDRPDSAVAKMIGWAGYNIALFPYGETTAVIGHLLYLLAEHPEVQKKAQEELDQYIGPPAPGSVPDAISEDDDYKGYLLPKGAVIWGNIWALTHDESKYSDPYTFKPERFLDEDGKLNEDSRVLAYGFGRRICVGKAVGSSTMWLVIACFLACFNIGLSKDEKGRPIPIKGDLIDKGGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETY1</accession>
    <name>A0A9P6ETY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aconitase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_912214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETY1"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="5">
        <location>
            <begin position="167"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="26147" checksum="BD8B00ED0485CAF2" modified="2023-09-13" version="1">MDPNLFATRLQPLLIPTIMPAGLYAHQINCKRERSSEYLGNLQQSSSPPDDILPSLRCLTTEVQPTKSSASSNDTRSWGHPPCNGPGGNNLQSEYEELSLPLDWQRKSAGVSQDEQSGWPPFELPSFKLSGIGPSFGLSTSKHSIISLETNIGHEIAIPSGHPLVPHTPNAGGLGMIAYGVGGADAVDVTAIIIWELKWFKVIGVKLSGKIGGWTTPKDVILKVAGIVAVKGGTGTIVGYLGLCGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU84</accession>
    <name>A0A9P6EU84_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TauD-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_841581</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU84"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF28">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE (AFU_ORTHOLOGUE AFUA_8G02210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="82"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="41247" checksum="B78B710E790FC90E" modified="2023-09-13" version="1">MSATVTATTDTLISGINSTLKLRSQDGDSAQKQEYRYAHLLPDFTREHFPPLTPFDHVDPGSRALTHSNPRAFLEGASSVVEITPHLGTEVYGVNLAQLDSTGRDQVALEVARRGLVVFRDQQDFIDRSPDEYLEWGRHFGRLHVHPTSGHPAGIPEIHLVYRDANSTYNFERDDSITSTLWHSDVSYELQPPGVTTFFLLSQPKTGGDTAFTSQVATLKRLSPQFVSFLRTLKAVHSGVEQAAFSRAGNRGGVVRREPVENVHPVVRKHPVTGEEALYVNRQFTRRIVGLKREESDTILRFLYDHIDKSADNQARVKWQPYTVVLWDNRVTAHSAIIDYKALGEARHGARVTPQAERPIPALEGLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUE2</accession>
    <name>A0A9P6EUE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_831204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUE2"/>
    <dbReference type="OrthoDB" id="2529242at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="974"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="979"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1174" mass="126458" checksum="5294424DD9ABFB68" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUQ1</accession>
    <name>A0A9P6EUQ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUQ1"/>
    <dbReference type="OrthoDB" id="3003645at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="177" mass="19283" checksum="C1200CFA624E73B4" modified="2023-09-13" version="1">MSSGTEMAYPRLLISSDKFNVIRTSTDDDDLPTPPALPENDSESLEARDIVLQLSTPFTSSSPIFEYPFPPYAAGSDPSLNSFSQPSRSNMISWPSLLRIESDTPPVGPPFTLSSSSIPTHSYPKLKIKLTLPTFPIPPSLMKKRPKWTLSILGKKKNTQGGATTQSDSIDRVLDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUU4</accession>
    <name>A0A9P6EUU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_843483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUU4"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF19">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="43070" checksum="C6E4955209E7D338" modified="2023-09-13" version="1">MSSIHFPQGHPGQDHEGHESQFYQPNYDTSGFHMNPMSQHPPRTPKSSIVASSSSHHYTSSSIYEEVPEPVEEEKADPEAEDIEIDEEETRVQEADKRIRDEEVMRDMIVTSNGRDKIFKLIQYAIKLGLWFHASTTSTRLLRRQTRPLWEQSIVARLTSVAAGLSLTRKLMLLFNWLHPLTQIMAQQSVPFSSEVSAEKAKKVEKPFLHTLLYAPPPVLLELVNAIADDLATWSKLGLFGQKFGERAGRLSDWCWFLTTMVGLVENGVERSMNGSLQTEVEGRLYTASMKGVTEKSKGKSTRIDEKELARLRKQDYWLQLTRAKLVMDLIFVSYDIFALKRAKDFVKAVAGFSAAILSSAKLYDRHRNILLKALLASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUV4</accession>
    <name>A0A9P6EUV4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_901414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUV4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="20319" checksum="7D251FD285F199FE" modified="2023-09-13" version="1">MNPLLVAFTDCSYGRCAFHDLQSVCWGSSHLFKQKPATSKSSGDEPIYSYIDLGEHYEGLRDVFPLIRPVIGMHKTYEEALQKLLDEKQPCKMAPWPSHSLFDLGPPSRVYLIIKGISEKKPVAIEQPDNNIDLLVDNAFNTQRADTKHALKMRLPSGPCWTICSVTDEWHHDDMIEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHX7</accession>
    <name>A0A9P6JHX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158021">
        <property type="protein sequence ID" value="KAF9521584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHX7"/>
    <dbReference type="OrthoDB" id="3270336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="420" mass="47578" checksum="063ADE15C035122C" modified="2023-09-13" version="1">MSNKSFYNQDRAFPPKPLVHDKDINKTNGNLYLINGDLVYSPNSARAITIPSPLPHGFNLFLPPRNFRKSAEWFCLWMGLLLYSIACAESQEESLCQFPALARTKWANFLVENGAGYNIDNVWVDELITSNVATFQACSQVGIFVHLTGDSELFQPDPAWFCQHGVPVWYRWTSEMAQNNRLARIIISKTLTGHNQYGGVLPTSSGTKRKDRQERIGGCLQKATFSPGKSSSENILGHYERLEIPKRDMDEIFDDCNNDKCCYDDVQNEWNICAFWSSRYDKDDNEDSPISPMSHYEGDIQEGDDMIPTSKNLSVPRSSNEWGPPSTLEISSTSTDNPEDFKLKQHLFRLKCFESKIVSVLEMHFGYTPLLPLPPALPIQEEAKLRSICVYLGFAWNSVFDLQEVFGKPSVCAGVDFFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI71</accession>
    <name>A0A9P6JI71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157961">
        <property type="protein sequence ID" value="KAF9522091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI71"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040176782" evidence="1">
        <location>
            <begin position="27"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="14233" checksum="D95DA953D04D4ACE" modified="2023-09-13" version="1">MGFQRCTLKTLVYIFSLLHRISPVQCPRSRLVITPSKNHNKTCGCRLTSNHDDLNHEVCVGYALCAFMWVIFNNIAHLIFEPTTMASPVALRLIFPEENDRDKSVHLSTIDTDPKIWSLLDNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIZ5</accession>
    <name>A0A9P6JIZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157935">
        <property type="protein sequence ID" value="KAF9522752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIZ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="19302" checksum="0B3E4545EB4212F4" modified="2023-09-13" version="1">MGSSAYVYRREHKTINWPESQSPRIPKPRLETDAIEKEAKDGFASWTSSTRFLAMSRPRHCDNVKNQVEESRCQGQNPRQGRYESDHRIEDQSAMPYLQRQGQNPGQGHYKLNHQRLTFNNVETKVENHDDIKDRPATPYLQRQGKDPGQRHYELDHQQLIFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJE4</accession>
    <name>A0A9P6JJE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJE4"/>
    <dbReference type="OrthoDB" id="2961245at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="360" mass="39692" checksum="D5C52E35840BB0CC" modified="2023-09-13" version="1">MSAAPDLSQILPLVFKGLKMTRDGNYSIAAAIAVIGYDICATFFDEMQLIWGKKWSLPKVLYLLARYYGLIYLIITLIVGSNTKLTSEVFVNTLCVLFPNRFPALTSVSCRGYLYYYSYGGDIFFTSIVNAIFVIRIHALYGKSQKILALFVSLCLIEFGFELGTTYIAAKTSAESATVNPLGIPWPGCIGTALPLKLTLLAWIPCLTVATILFAFTIFKFKDALRKQAIISRSESQEKINNLSPMMVVFIRDGSLYFFLIFAILLLCTVLIVPRDEDSALPLMPWIIAVYSLSGSHLILDLRKAGQNGVNQHSDRVPDDTLPLAFAGGSGPAKYNFPAAKLYRQPDVTSTYGHSSSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKB4</accession>
    <name>A0A9P6JKB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKB4"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="168" mass="18790" checksum="E5D9F38EEEF1F312" modified="2023-09-13" version="1">MYCSNNLSISAKNVIGRSFFDFVAEGDKEKVKNCIEIVKEWDVDEYGQPCASGFEFCRFALLAKGRDSAKHTLKPSAFSQSWLDGKYQEEIYTKKYGSRFYDNFVDSNTSVHSPFTLPRASMPKTYSGSTSLYDVAGTVEDSQTQVEAILSAHSDGLLAILTSWRKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKI7</accession>
    <name>A0A9P6JKI7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_910065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKI7"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22840" checksum="52C92F57463E422E" modified="2023-09-13" version="1">MPVYEILSVPASDLLAQDHSLFQPLIDHMSGADGILEVRYGFTEENEKNFYGIIKWETLDHHKAVRQSPGHANFREKMQPLVAGKPQVVHIEFEKDPSAAFDAPVTEITWFLLKDGITKANIKEIVNQEAGSKMLTLPGIIPGAAWNETIEDPSKCVLFGGWESSKHHIDGIKQEMFKEPFGKMMTLADHTTEHVSFHTAFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLU2</accession>
    <name>A0A9P6JLU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mob1/phocein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLU2"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="27542" checksum="7D0C646040906C51" modified="2023-09-13" version="1">MFSSRNRNPRQRRSPTPSGGTTPRTPGGPNGPSRPASPQTPGGKPLYLCSPFADAALVKGNFKTIVMLPKYVDIMEWVAVNIFDFYTNLNEFYGVIAEHCTQHSCPNMSGGPTLNYVWTHQGGKQANLPAPTYIDYVMTSIQNLVDDENVFPTKTNQAFHATFPATVRTIYRQLLRVFAHMYHAHHPQILHLRSEPHFNSLFAHFLAFGREYELLDVKDIKGEPTASVGVGLLWERWKEKGILEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM10</accession>
    <name>A0A9P6JM10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM10"/>
    <dbReference type="OrthoDB" id="3067187at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="657" mass="71278" checksum="475F2CE407DAEDD1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM25</accession>
    <name>A0A9P6JM25_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_859983</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM25"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000003">
        <property type="entry name" value="COP9 signalosome complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="12">
        <location>
            <begin position="53"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="282"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00058010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9525229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="359" mass="40050" checksum="9C03FE3809E98267" modified="2023-09-13" version="1">MASSGTALKSFSLTNNILEVSPNDEIYRFDAEANRKLNRESPWTKDPHYFKSCKISAIALIKMVIHARSGVPYEIMGLMQGKVVDTSLVIMDSFALPVQGTETRVNAANEANEYMVEYIGKSEKAQRMEHAIGWYHSHPGYGCWLSGIDVTTQLNNQKFQDPFVAVVIDPNRTISAGKVDIGAFRTYPENYTPPNVSQSEYQSIPLSKIEDFGVHANQYYQLDVEIFKSSLDNDLLAMLWNKYWVNTLSQSPLVSNRAYAVSQLTDLHQKLSKAQNAVQSTRAYAPTLKEKEGAAGKQKEKDEKKREDNQLTKSVRDSTKIAVEAQHGLIAQVIKDVIFSMRPGADGSKVAEVTDMAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMS2</accession>
    <name>A0A9P6JMS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_837754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMS2"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="21176" checksum="09BFA3A1EE3C89E3" modified="2023-09-13" version="1">MVSSKVAPQSCTSGRQPRIQREVSKALAHWSQIRNKFGNTNENKFEDRKWLHNVLPELIDGTKADAGAITIAEVGYDAGNSAFPLLSSNQDPAFRIIIACNGAGSNETRLYERWLSQITNSWVEKEESRHHHDGFGFFCATSSDVLLYDPAILEVISEPCRRSWMQIPTTSSCAFLALRAAYRPSSIDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP16</accession>
    <name>A0A9P6JP16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sec61beta family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_856507</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP16"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="10175" checksum="C5B8C0DD77FA9582" modified="2023-09-13" version="1">MSDSDSSRSVTRNGSVSKGPSGTAQIRRRAAGSQVAKPNSSRAAGAGGSSNTMLKLYTDDSPGLRVDPFIVLVLSLSFIASIFFLHISAKVIRAFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP43</accession>
    <name>A0A9P6JP43_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP43"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="662" mass="75940" checksum="B8145CC56BE3EE2C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPD9</accession>
    <name>A0A9P6JPD9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_792374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPD9"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="61"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="587" mass="64450" checksum="0C83308CFC660DB6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRB6</accession>
    <name>A0A9P6JRB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRB6"/>
    <dbReference type="OrthoDB" id="284718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="101" mass="11265" checksum="5CB88669DFA2099A" modified="2023-09-13" version="1">MSVNKDDPRDSSLEVPYTFPNIWVKDSNDGFGVSGMFLSGLIMVTRNRFLAWPSVLFGINQVINAHPMRNKEGGMGWSNLALCFSALFASYIPVFMITQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRU9</accession>
    <name>A0A9P6JRU9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_763549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRU9"/>
    <dbReference type="OrthoDB" id="5865767at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18434" checksum="22954C6435079970" modified="2023-09-13" version="1">MSASASSSRSGIRVSPSANRPHQSTSSSHSSSKSKGKDKYEVPEPVKSDLIRSYTMQHAESGLGKDYIKRQHVLRVRLEGEQFLLQANNVESVIAWIEGFQSAANVALDLDERPMPAGPIFPRRRRRRRPAPAGSNSTSVSHVINPSPTIPNGPLAGVRPLERSAGRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSZ4</accession>
    <name>A0A9P6JSZ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tryptophan synthase beta subunit-like PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_880651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSZ4"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="2">
        <location>
            <begin position="42"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="2">
        <location>
            <begin position="95"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="24412" checksum="A23962507BAE2645" modified="2023-09-13" version="1">MLNSALDAIGCTLLIGLDRLAAAEFKVSNVTFVRQRLPLDGKIEFFNPGESVKDRKAYRMIVEAEDSGVLIPGKSVLIETTTGNAGVGLAWIGLLKAIPNAVMLDQFKNANNARAHELTTGPELIEAKESTISGDRSTSGKIDAFFAGCGTGGTLAGVSKAVEKKKHNPEVKIIACNPIGSIIARPEELNDPDAPLAIEGMGLKFIPETVEYLCIDQWVKVLDQDGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTA8</accession>
    <name>A0A9P6JTA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_586994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF51">
        <property type="entry name" value="SNF2-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="431"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="1043"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="595"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="927"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1248"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1276"/>
            <end position="1286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1286" mass="144423" checksum="82E0F11DA6D645E0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUD1</accession>
    <name>A0A9P6JUD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUD1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="16325" checksum="E6E8F9AFC82F3362" modified="2023-09-13" version="1">MTLPDRTQYYYVRNTASNRYLRATLDGAVYTGRKIADSFHAWHFYPHGSGLQIRNVASLRMLTLGSYSDDEGGYYQLKMGGLEHGDEPWKVASVGGQDAITIEFPRASLSLLEYGGAKPYAVTRKFEGGKELDRTHWVLERATVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUS6</accession>
    <name>A0A9P6JUS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUS6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="42159" checksum="596CA4BA249015B8" modified="2023-09-13" version="1">MLGALTIAAQANSNTTEGALSHGTAKRSGRRQQMLTSTNDPEARFWRKLLEFVISPRSREDHEELVKRMSTLDPEYCPCSTEIPEDCANELIRGRSGTRRPTLSASHYRLQGQMQLEVPATFSTYLDHVADAQLSIESRLFDVGVTTLGTHLCGRSPGLRAKYPMPNTVSRSNSHRQRPSDSSLEGRIASGPPPLRKYRPFVQNGANSVSFVPINLAFAAMSIIFKTLRALEFVESSECATHLHSSREGIGLAMSYQFWDLWSFIRVALDHPSVWRDNLFWQFEFLVLQISSLALYLNDDLRWLKLVRKSDHHRHGRARAIYIGHYFRNKLSMISAKGGFQTAVLLHPDIIPLPQTIATPHQRGEAIHVQSISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV98</accession>
    <name>A0A9P6JV98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_757088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV98"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="5">
        <location>
            <begin position="118"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="39840" checksum="5BFC05E0DB11D470" modified="2023-09-13" version="1">MAHWRAEQQARMYALEKLDNFRWISNIMAGYGRQELSEDDVVPETTLQYSGQFSEIVYSSVSPELLIKHYEILAQPEFPLEHFNALRDCITAGSYRGTLADVPTYIFIRRNSGQTQLVVSICGTASPDQFRQDLRVLKTPHRSGHGNAHTGFLALYDGIKADLMKGIQDLVITGHSMEGSIAYLLCLDLLADYDAMISTLRIRIVSFGAPRTGDTQLVNYFHTKVEAFWQRSGRASFVEYAVKGYSDGIPAVPPVIMGYQHFCEEPFYSAYGRLYRVPTADSEYATFRFKDGENQNRTLFPQGSHNYYNSRDLEGFRRKLDWLVEAKFPEPGWEDHYRDKLRDSNSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVI5</accession>
    <name>A0A9P6JVI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVI5"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="15"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="28091" checksum="1583C01988413910" modified="2023-09-13" version="1">MPATRLKFDEYEAWIVIEDRETEVYNVENDHETKTVTCWIASEEGKNFTIYARKKHKKFGCVFKPSVDGVSIRGIKLLPSNTEPHQRKGVPTSSGTSKIFEFTRLPVTDDDTYLEQGIGQGVGEIRVDLHRATFVRHTKAKSAKFKPVNGLSQSYKVHEKAKKAMVHRVQCIKEINESHTAKFTSTKLEIVVSFVFRYRSLNMLQANGIAPRPTPPPEVQRTSSSKGKRKISQLRKKRTRWKMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E347</accession>
    <name>A0A9P6E347_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_735569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158008">
        <property type="protein sequence ID" value="KAF9521636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E347"/>
    <dbReference type="OrthoDB" id="3265515at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8463" checksum="BADFCAF69C877492" modified="2023-09-13" version="1" fragment="single">WTPGHEGLEGNKKADEEARKASEKGCSRTQLLPKELQSELTHSRSAVRGAFQKRLKEKAKKEWRGSKKFKRLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E407</accession>
    <name>A0A9P6E407_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="6">PME-1</shortName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_864906</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Demethylates proteins that have been reversibly carboxymethylated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E407"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="113"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR022950-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9522149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="41616" checksum="3A7C51D3287AF693" modified="2023-09-13" version="1">MSNLYKSAIGARLAKLPADIPYTRHPGADEDAEADEEEENDLIGDLPGSGLGPPALPANNPRNKPKRAPNSAFSPISAAGFFEDASQVSLPDRGLDCRVYYTSPKSKNGTIMVCHHGAGYSGLSFACFAKEVTGMTKGECGVMALDARRHGKTTSTDPTDSDLSIGVLIQDFCALLQTIFPDPSSSPTFLLVGHSMGGSVVTKSCPILLEKKYKIAGVSVLDVVEGSAIDALPHMNSLLNARPDGFDSIEEAVEWHVSTNTIHNANSARISIPVIFQHKEGSNPPYQWRTPLRSTAPYWLSWFQGLSKAFLAARSARLLVLAGTDRLDKELMIGQMQGKFQMVVVPGVGHMLQEDDPTRLAEILVEFWRRNERVVIGIKKVGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E498</accession>
    <name>A0A9P6E498_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E498"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="9097" checksum="A0D6A9B3A5090425" modified="2023-09-13" version="1" fragment="single">MVLRRNILSRQNGQDRCRVLLTLLSGLYDILTHATDYSLKHCYQSTARQIYYHKKVMVYRGSTVSEDYTVLSRDVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4J7</accession>
    <name>A0A9P6E4J7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_777304</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4J7"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="58224" checksum="2D40F9C693FCD268" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4P1</accession>
    <name>A0A9P6E4P1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4P1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="59" mass="6252" checksum="A0212508E5897035" modified="2023-09-13" version="1" fragment="single">SSLPSPSTLDVAPSDHLAVIILTISPPRLLHFPPCIATFLTFSSPSTSSFKVSPPIYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5H7</accession>
    <name>A0A9P6E5H7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5H7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="17480" checksum="A8CC97C63C41E416" modified="2023-09-13" version="1">MRPPYPMVGVNSGVRTYFWNHAFIGWNGVIYDGCGGPHLGTEDVGLPGYSYQHRQPTSSGWRHRHMTAMPTGPNAGKTSENTEKFLQSCISTNAPRFSQIHWVHGIPELTKHFLDTPALGRGFPRRSKGFIHFLRCRVLLLMTWLRARVMSTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5M2</accession>
    <name>A0A9P6E5M2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_69680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5M2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7757" checksum="2E65F9A0BDF25858" modified="2023-09-13" version="1">MLYHKSDSFGRRDWTQNHPTHPTPTSLCKTQAPPVQQTSRCQPNQVERTEMSTCFKVYHPQSQVGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5U9</accession>
    <name>A0A9P6E5U9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5U9"/>
    <dbReference type="OrthoDB" id="3264182at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="9748" checksum="3BF6B25228A9FF1F" modified="2023-09-13" version="1">MKLTAPQELDSYYEASTQAVSRNWRGRGDASRTCMLSEIADYRRHVCRVEVSQATIYRTLCRCGFSRKKVYFFIDPNARFIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E605</accession>
    <name>A0A9P6E605_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E605"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040326330" evidence="1">
        <location>
            <begin position="21"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="13374" checksum="A65A453EF4C7A8DF" modified="2023-09-13" version="1" fragment="single">MFFSLGFAALLSSLIALTSANQVCEGYNTGVAAMYNVPNTNLHSWYVYSAADCYVQDMKHIDGDGNICTSGKFDCAPDGSISAWYDTTDRSIKHNCIPNPTPDEHCGGDKNLPIPVCCDKLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E637</accession>
    <name>A0A9P6E637_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_898999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E637"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="564" mass="61744" checksum="F463F1EFA793AB38" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6D1</accession>
    <name>A0A9P6E6D1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6D1"/>
    <dbReference type="OrthoDB" id="3067134at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="366" mass="40449" checksum="637F47A749AA60B5" modified="2023-09-13" version="1">MSPIIMTQPTTKAAERARLSSFFDRLASHRPHAAAAVTRQAAIATDESLPTPQEFNTVLKNLYNLVQSKKTTRRSVVAWPHKLTADSMEMDEDNDEGDLTGESEMTEPSEPFPQAEEKKYPFTFKHMIHKLYKKDEWEKTVKDMLEKSKREYKPLAEVEIVSGPPGLERPVVAVRGRKAGDSSRRVSCGIGMAQRTRSSSGVGADLGCGTRRRSQSVVQGPKRMAMSPISPTFNIPPIRPTGVQHESMRAVKKRCVGKRKSISGLFVERANENVSSGNKGTWVFESTISSTENYIPGVYSPMSSPPESPVDNNFSGSKRRVLVDNQIGVGAAAPVQLAISVDKVERTTIKRRSLVVDTKLAKTYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6I6</accession>
    <name>A0A9P6E6I6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157917">
        <property type="protein sequence ID" value="KAF9523447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6I6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="32402" checksum="DA8144D1E02AA031" modified="2023-09-13" version="1">MPSIPNKLISEINLYSDIKTAFALTMLTKIDYPYRRRQLWTLQNSIGPLLELLPARVWKSISPHKPLSHQCRHCKQLKAKEFDRDAAAFDNGTRQLLVSLGDQMEQLVIPTQNRCYFIADIAEGALEFLHNQFDCPLLSINSIECWKTNEDQFNGCCYASQSYSFLQNIMKTCQPERLIRFDMPYISPNTNNRTGEMLRMLGYNLQELCITFQSRPTVLGENASTWINLTKLCLVADVLDSSLVYQNIAPLSSLQYIRLDVHLYSSRAHPLSTNLSFPNLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6S9</accession>
    <name>A0A9P6E6S9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6S9"/>
    <dbReference type="OrthoDB" id="3067415at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="82" mass="9603" checksum="C6C379D688EDCD88" modified="2023-09-13" version="1">MVNTLMDEIKALREEFLAKEQKEKEELHSMRQLHSAEVDALRRRLAYLESRAPPPFDIYDRTRRYPPPLPYDGYGPVSVPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Z4</accession>
    <name>A0A9P6E6Z4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_681698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Z4"/>
    <dbReference type="OrthoDB" id="3229610at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF158">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="34"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="38874" checksum="AF71663B3648D6F9" modified="2023-09-13" version="1">MILETRKLTKPSEEDALAILIICHTFAMLSASFRLAYRYHIRRLWWDDFWAFVALGSEVISVATYFSIPTSPDARSIGVEQAGRYLDLFFYTTAVWAARLTVSVTIVRLLPPGPLRRGSVWVSGLFAFFWFAMVLQKMILCEIKLGKHDVQCILPFETAVVELCTCILGDIWLISVPVYMVYKMKLRREYHSLIMSLFMCGIFTTLGSVVHKVFLLLGEIAWSAITAQIEVAISIVVSNMLVLVTYLYRRFHHPSEDSQTVPSDHDNRFSRVETGRSIAGTRHLVTYFSNHGRRGTEMLHLGSSFDTVQYHPNTDHYIDPRHPVSSPANPVAAHLKGRVLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E731</accession>
    <name>A0A9P6E731_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_651350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E731"/>
    <dbReference type="OrthoDB" id="3042126at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="251" mass="27796" checksum="9A62F4C14E9BEE5A" modified="2023-09-13" version="1">MSSQYDIIFEVSRYSPMDAQRFDPSKRQKSLSSSFGDSIDEQISEELRSHSPASSATNSTSSSWEDRVIAILASPISATHYRKAKKSNSSNSLTSQSSHNSQTSPTSLVVASTTFPAKNETHCTDVFEHEDSTTTTRTIIRPTRSRSTLFCLSPKASIDNLTSTRSSSPLGLNKLEGLNCLGGQSGNFEDAVDMIQQEREKKLTGVQDTMRVCVYQEQTVVREESWRETVGAMLYEKPRVMNSVVGRVEVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7G0</accession>
    <name>A0A9P6E7G0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">laccase</fullName>
            <ecNumber evidence="5">1.10.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_910266</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11276"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17594"/>
            <dbReference type="ChEBI" id="CHEBI:17977"/>
            <dbReference type="EC" id="1.10.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.2" evidence="5"/>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7G0"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052716">
        <property type="term" value="F:hydroquinone:oxygen oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13903">
        <property type="entry name" value="CuRO_3_Tv-LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000045">
        <property type="entry name" value="Laccase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000112">
        <property type="entry name" value="Laccase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0186">Copper</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040147105" description="laccase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="17">
        <location>
            <begin position="55"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="15">
        <location>
            <begin position="168"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="16">
        <location>
            <begin position="371"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9523941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="521" mass="56737" checksum="5C8CD81B9F599675" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7H2</accession>
    <name>A0A9P6E7H2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7H2"/>
    <dbReference type="OrthoDB" id="2587912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34255" checksum="A538216082C3D870" modified="2023-09-13" version="1">MLPIDIYHEILRESLCKNISPTALSLVCSLFHDIVQQVLYTYLRFKSRSQLILFTLTYRTNSTKIPLPPRRIGLDILGNDSHLVFADLYDLFSGCFSDPLFHGANVDESGRLLLDELSLRLNSHAFDRKLDMIYTSLSLIRFRWTGPDPPHHFSIAIVPPAIPRLFSALSRYTCLEDLELSHLAIGVDTASQLPVIPSLRRVHLGQIILLSPLMIARLILHPATSELETVTLVDAYRESIWGPRLRGIDVERAAEALTQTGAEDVKNSSLLDVEHAKTLIKTKLRCEAKTERIIGGDRVDAGILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7S6</accession>
    <name>A0A9P6E7S6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7S6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="12744" checksum="15C21D52CF053C01" modified="2023-09-13" version="1">MRRVITGERPFLNLLALPIFILWTYAPNRLIARSMSHDDLCHHEDSPPRQQKTPSSMVTDKFGESNDIKQELVAGQTALRFMCYMPHLGSSISNKNVKVSAQIIGFGPSKLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8L3</accession>
    <name>A0A9P6E8L3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8L3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="17608" checksum="3951072562429B8B" modified="2023-09-13" version="1">MFQHLGNSWAHGGAAERCIDDTSPASYNPRTSNVQRLGSWLDPSVGADLDRRMKNPSAILELIAHYSVLSCRIDYPSTNVPHPIIFLANAFHTASDPLPLPTLSPLLLLRQHSAAHQAFVVPRIAARGTSQATSMKTRSSSKSLDSSSTISAIFTRTKQAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8Y9</accession>
    <name>A0A9P6E8Y9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8Y9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="28774" checksum="5C81E8E04BF92864" modified="2023-09-13" version="1" fragment="single">MAAQQDAAVIWPLDQVKEYSNDWLTRISQIESDGVLDRPALKAMIIEIGLSPYFRSALSHGYQGRLNSEEVPKLFRQLWALFKNNQEDLVDSQWKELKIVLLGPSAMPKQNIEPSGPPTSQSDSSTIPPGEIQKPHVLSKTVLATKDAQEVTKKTGGEDVMHVDPPAHSKASRTEENPDPESEKQIEKGKQKATGEKFHGALKKSETHSFKVSVVIPPGRSDTRKPNPGPASKSAECGDAKWTKSSTIGDTKGKANEKTQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9T4</accession>
    <name>A0A9P6E9T4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_548281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9T4"/>
    <dbReference type="OrthoDB" id="60858at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040183678" evidence="1">
        <location>
            <begin position="23"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="185" mass="21082" checksum="A8FBB29B00D0824A" modified="2023-09-13" version="1">MAPPKTYTWISLWFLLSHTIDAWDIAYILLRPHSLPGSQYRWIWKPYDDLEIIDKNYDVQRFYEGKSTGLAAKAVLSIAEVLSAVIYLYKAHVSKSSSAPLYGYTSALATILKCALWTLEEVYCGWCTVGHNDTDGFIRAFVGPMSYVVGILSEKSYTDHECTQDLDITFYCVSMEVLERHDSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9W2</accession>
    <name>A0A9P6E9W2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aip3p/Bud6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_909430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9W2"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056279">
        <property type="entry name" value="Aip3p_Bud6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23153">
        <property type="entry name" value="Aip3p_Bud6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aip3p/Bud6 N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="128" mass="14176" checksum="53A717DE76D3981E" modified="2023-09-13" version="1">MRSESPATRAVDSSVTRLLTLTKQLLSVLNDWPEDNRTEEDVRKASQDFHDGFIVAVKCFGQFNISLQGILSVPNEVSDGVEVILAGERTRAGVDANFEIIRSPLRSLLNGLRPSVGAWDEILLVPWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA81</accession>
    <name>A0A9P6EA81_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_771625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA81"/>
    <dbReference type="OrthoDB" id="3261131at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="285" mass="32360" checksum="DEA1055FAD438FFE" modified="2023-09-13" version="1">MKTYPLESLRQNALIKILTSTEILPARLGPRTNDSYINDGPIFHFCKPSPSYLQEVELEVIGNTSDPYLRSARYYLEYCRKYLTNRQAEYHHLNFPVILLCQMGPLFMISVGVLPNMPIVESIATISLHTNSTNENGMKAGACVLGALRIAVQGISRAYENGHPANSNNSNSVSGDTQAAIKFTYTFQLESKRVFFACTKDTQKSIYVKFTMRYSTAAHNALTCYAPPVLAVMRYYQWLMVVMGDVPDRYMTMADWIVSPAMPLSIFKTRYIYSQERSLCWICSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAM9</accession>
    <name>A0A9P6EAM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAM9"/>
    <dbReference type="OrthoDB" id="3199068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32539" checksum="786FFEA058D3CA94" modified="2023-09-13" version="1" fragment="single">MNSPVNFSFGTPNSSADGASVMENHSTYFFDMVTFEVENTRFRVPKNGFVKANPRFFDRFSLPRLPMGNRTSSVEEQTIALAGITADAFHGLMLLMYPFEETPSYNEWIGALDLATQWNFKDIRAKAILALSTLNRSGNISQTPTELILLAKKYKVKVWLREEYIKFVKMDDLKLEHLRTLDWETISRILAAHLYYGRSEKSVSAQTKPLKCSNCCRDPAAMSGLFDHPCLLTCQKINGFNHCSPCRAGNKWGCERKCSNLKWKDQTPTTAEAHVDALFSSEFSSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAS0</accession>
    <name>A0A9P6EAS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAS0"/>
    <dbReference type="OrthoDB" id="3058840at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="29216" checksum="D4FBF6E4842F0536" modified="2023-09-13" version="1">MTSEFQTKRIPKQGYAGKNGFLRPPTEVAQNIPDAVDRHRLATFIIENKKRSVPNFEQMKAEVALPDDAAILQERVKRLVEDHHEDLNKLYDCHATEYVNEIVDRNASKPGISEDPELESRLKHLYTSGFRDAPTQLDWTNGYEILRYTFLSQFLALKTQQLELEQQEELARKQREQLFPQSKEDFHNKPHDVQMRAARFLVADKIKQERLISQYQWAWRQVKPLQDIFVKDEEFSAEIRSIIITSSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAZ0</accession>
    <name>A0A9P6EAZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_517494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAZ0"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="191" mass="21241" checksum="D9B9BC9DCE795662" modified="2023-09-13" version="1">MNAVAMISRACTGSLFYMRVKVLYSSIRLVRGLLAVALLASVAGATLGFWTVTSIRVGVPSGAPLSSYKGVCVSQAIAPYWLIALTPATETIFDIFVCLAVTYKIQQYQDDTNLRQRDNVPQPGNNWRKWIYRSKGRPLSRLADRFMRDSQFYAIFALYIKVSQILLIIITPFLIQTTSGVSLMLSFPDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB29</accession>
    <name>A0A9P6EB29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB29"/>
    <dbReference type="OrthoDB" id="425354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="8890" checksum="D8F12C5353476408" modified="2023-09-13" version="1">MQNKSLTDEDATDDVLSLQCVGWVTRKASKMASVTLSIKQYIGADGVEKIEISQSVSGASSQTEELVLVWKSKWMKLAINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB46</accession>
    <name>A0A9P6EB46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_859186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB46"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044594">
        <property type="term" value="F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF56">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="3">
        <location>
            <begin position="32"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="2">
        <location>
            <begin position="179"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="33203" checksum="AAD29418E1E3E050" modified="2023-09-13" version="1">MLPLQDPNAFADEEDSDLVRENKKVVPEPVDFSYIERDVILYNLGIGSTEKELKWTYEGDEDFQALPTYGVVPMFSSMSSLPLDWLPNFNPAKLLHGEQFLSIKSPIPTSGDLVSEARFLDVLDKEKAASVTIIIETRDKSSGKVIFENQSTLFVRGAGGFGGKKTGRDRGAASATNEPPPRKPDAVVEEKTSTSQAALYRLSGDSNPLHIMPEFAAIGGFDQPILHGLCFMGIAGKHVLKTFGSYKDIKVRFGGVVYPGETLVTKMWKEGSKVIFITSVKERDSIALANAAVTLVDPSTKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB51</accession>
    <name>A0A9P6EB51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Phosphomannomutase</fullName>
            <ecNumber evidence="5 13">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_770849</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB51"/>
    <dbReference type="OrthoDB" id="10264771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00445">
        <property type="entry name" value="alpha-phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01143">
        <property type="entry name" value="C2.B.3:_Phosphomannomutase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9526133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="256" mass="29149" checksum="2FBEADC449A9AD55" modified="2023-09-13" version="1">MVSSAFADRPQKKLFLFDVDNTLSLPRQIASPEMIQTLRELRKKAVIGFVGGSDLVKITEQLQTPGTKVLDEFDYGFAENGLIAFKQGKPLPSESFINFVGEEKYKPLVNFILHYIADLDIPIKRGTFVEFRRGMINVSPIGRNATIQERQDFEQLDLKHGYRKALIKALKEKFPDYGLTYSIGGQISFDVFPNGWNKTIALKHVEDESFEEIHFFGDKTYEGGNDYEIFSDPRTIGHSVRDPTDTIVVLKTQFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB96</accession>
    <name>A0A9P6EB96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_896852</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="238"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="301"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="454"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="970"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="977"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="999"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1140" mass="125289" checksum="CBD4AA753FFE0C86" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBX2</accession>
    <name>A0A9P6EBX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_858230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBX2"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="9">
        <location>
            <begin position="461"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="617" mass="69854" checksum="B83E667E464E4503" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC91</accession>
    <name>A0A9P6EC91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC91"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="200" mass="21949" checksum="C4B8232EC63D5E58" modified="2023-09-13" version="1">MSNPIFSHTSEGPPSPRNLSVDLYPIESVAHAGGDSQSHQPLAETLEFPPFPTYDSIDLHPLPTLQNLVSSNIQTFTSEATNLADTTREPFPLLHFVELVSVTDTPQSRESFESDTPLSHDALLYAHGDLSTIEASTISQVIPTSRADSGEGLKVTLPSAAAVSTSEADVKSQDDADDMGPEEPFDRRQRHWIMRRDPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECF8</accession>
    <name>A0A9P6ECF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">(2E,6E)-farnesyl diphosphate synthase</fullName>
            <ecNumber evidence="6">2.5.1.1</ecNumber>
            <ecNumber evidence="5">2.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dimethylallyltranstransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Farnesyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Geranyltranstransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_857803</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.1" evidence="6"/>
    <dbReference type="EC" id="2.5.1.10" evidence="5"/>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECF8"/>
    <dbReference type="OrthoDB" id="10257492at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000006">
        <property type="entry name" value="Farnesyl pyrophosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040340905" description="(2E,6E)-farnesyl diphosphate synthase" evidence="17">
        <location>
            <begin position="27"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9526435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="425" mass="48813" checksum="D1EAE0003227D5B2" modified="2023-09-13" version="1">MRCPAPRTFLLFFAFCFLAVTNSTSSYPSGTCNVSINLEPWRDQLGFCVRPTARPYSSHSNHLSIDMADVKAARRTKFESVFVKIKNELIGHITEEGMPPEAIEWYSDNLQYNVPGGKLNRGMSVVDTVEILKGRELNEDEYFKAAVLGWCIELLQAFFLVSDDIMDSSITRRGQPCWYRKPEIGMIAINDSFMLEGAIYKLIKWHFRSESYYVDLLELFHETTYQTEMGQLVDLITAPEDRVDLSKFSLERHRLIVVYKTAYYSFYLPVACAMLVAKIPQTYQVPPSKTVNPYDIALSILIPLGEYFQIQDDFLDFSGTPEQIGKIGTDIVDNKCSWVVNTAIKLANPTQRKILDENYGRKDAEKENKVKAVFEEIGIRQAYETYEEKAVQSLRRKIDEIVEVDGGLRRQVFESFLGKIYKRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECR3</accession>
    <name>A0A9P6ECR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_884805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECR3"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="543" mass="61200" checksum="70E53ADDA05B01F3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDJ1</accession>
    <name>A0A9P6EDJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_869976</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDJ1"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000433">
        <property type="term" value="P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF2">
        <property type="entry name" value="ZINC FINGER PROTEIN RSV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="224"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="385" mass="41842" checksum="59FDBBFAA7A6675A" modified="2023-09-13" version="1">MAEDAPKDTEDPVNKSPSSPPRRPTTRSQTGTVAKRRTRDDESIVETKKRAPTSRKRQKVTATATTAAESVGSETPGSSSPKPPLTREPSLSSTSSTPALPSAQQPQLTFYHSSMSESDQPQARLPRSRASLPTPIPNLTKKSRGRRVPTKDTAAPVPEPNQKDTRLYVCTVEGCGKCFHRGEHLKRHIRSIHTHEKPFKCTFPLCEKFFNRHDNLLQHLKVHRQGSSLPDHPPTVPKRSLQDEANDGTSASAPPQRRRGSFSAAEEEEEEEDPNSPNSPPARPRTIYDAYPPRYAPFAGATSATAPPFQQNPLQAPPNGTITTANGPGPTHGSMASNDPMSLLTNVAISSLRMEVSSLRTEIPQSSADPRAVPVVAPVVEMTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEE4</accession>
    <name>A0A9P6EEE4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rho GTPase activation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_855894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEE4"/>
    <dbReference type="OrthoDB" id="19923at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="82"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="253"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="75050" checksum="C5F5F982BF14E6E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF51</accession>
    <name>A0A9P6EF51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_855554</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF51"/>
    <dbReference type="OrthoDB" id="2690153at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="495"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="548" mass="59732" checksum="ED1D59B7EF062FD0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFY8</accession>
    <name>A0A9P6EFY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFY8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="7583" checksum="9D5231C5AED0B9DA" modified="2023-09-13" version="1">MALQPIRYYLKMHPRPVPQLSWKVCLYFLYFFFTLRICTLIVGSCREGRRLAADQQTRRSTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGL5</accession>
    <name>A0A9P6EGL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_308861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGL5"/>
    <dbReference type="OrthoDB" id="2927144at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="488" mass="52134" checksum="40476EE20B2FA4D3" modified="2023-09-13" version="1">MGASIIVDDADPKLQPYFSGDQWGLEPGTGDSLLNGTLTSCHLEKKSFYPTPTFSLYFYGSDFSLYGPGLSGVALNYTIDDTSVRPATDFNNSASTNLKAGVKLWSLTGLDTSYHTLKLIPASGLFAFDYFTYTPSKYTTLTGSRLIVDDADSLIQYSGNNHWTKLNSQIFGNGMPYQSTLSSSSQKGSTLKFDFTGSSIAVYGALNQQSGTLSAQFTVDNGTATTFTPFNGTQAVDPSSWKINQQLYYKDLAPGKHSLQLTLSDISGSQALYIDSLVYEGTSGTTLSAANPSATGDSAFSSPSSSFFSSAKIGGIVAAAVALAFVACCLRICCVRRRRVIQQPNQPPTLLLVHQNQKPPPIFSPPSFNRHESAWSSNSRFTPSSPPETPFTMPTPMPPPPPPHQGPPAINSLLGLLSRTPDATTNPGMPTPVVPTGIPTTPTHPAQHMDGSDEPARPAALMRERETGSGPAPAPPPYRERTSTDTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHH5</accession>
    <name>A0A9P6EHH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHH5"/>
    <dbReference type="OrthoDB" id="2968423at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="66411" checksum="13A9EBEEB5E1F3A2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHS9</accession>
    <name>A0A9P6EHS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHS9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="11544" checksum="1DFD44DE9C42F6C5" modified="2023-09-13" version="1">MKIQTSMRLMYLLLLYYLLILVFLTSKLLQRLEWPLILGPSHRSAEPKHRSLCLNWAFGVTLMHFPAFRLVGRLRGDRTMGHQFITSSISFDCVSMLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EID0</accession>
    <name>A0A9P6EID0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_852691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EID0"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="91" mass="10605" checksum="8D940E10D9EC8BDD" modified="2023-09-13" version="1">MDPWWQEGIESQAVDRVNRIGQKKDVHVYQLIAENTVESKVLDIQDKKKALIQQAFSGIKRTETQRQQREARLQDLVELFGVRRKASQVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIX7</accession>
    <name>A0A9P6EIX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIX7"/>
    <dbReference type="OrthoDB" id="2651020at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="21888" checksum="5A6312F7EF8A034F" modified="2023-09-13" version="1">MPYAAHEIYFIDPHSDDMDLCHLLQTMKLEVSNPEKTSENVVHILPTPNIVADEVMEEDRTYQPDTVDPQLASSNSDTREEGSFGCGYLRAVRHQMDWGEYPTTGGEYLDAIFTHREILYAQPSAHQECARAFSDIATLLQKRAWRADREADPEAVAAFNHEAWVIASTLSPTQNSADSHRVQSQSVCVMMPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJK8</accession>
    <name>A0A9P6EJK8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_851233</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJK8"/>
    <dbReference type="OrthoDB" id="347657at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="16"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="352" mass="39285" checksum="F0AF54887AB3A22E" modified="2023-09-13" version="1">MSETKTKPTPPTLADFELGEELAWGSLATIVDVVFKRNQKHYALKILNKAQLVKKKVIRSALIEKDALIALGTRPNPHQGIVRLHHCFQDNTHLYFALDLATHGDLKALVLKLGSVSLDCARFYTAQMVDAVQYLHVSGISHRDIKPENVLLDAEWRIKLCDFGCAWVGTPKDMDVSRTNTFVGTAAYISPELLERSKSHPTSPDLWAIGCTLHFFLFGASPFLAATDYLTMKRVREQDYSIPEACDANAASLIRALLVSDPTERLGVSPKSSPSKLRQHPFFVGHPTKGTDGGSQNVASSPQKRWLTVEWEALWTKPAPEIEVGPYRIKPQQPVETDDLWESFEGLEIVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK29</accession>
    <name>A0A9P6EK29_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK29"/>
    <dbReference type="OrthoDB" id="3241493at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="428" mass="48509" checksum="724F8D6F4CAE694B" modified="2023-09-13" version="1">MSTPDDLPWPELGNVSRGATRGNQGQKGVLGPSDRDGRCVLQLRVQPGVLAVKLNRQSSEWYRTLDNEVNRALKMTKTYWRKARRRQDYDARADQDHMELHEWLQQLKDKTMSHLELLMQKGDIQGPPYVMPDDIELSFLRKFIERQAAGIPHNPRLRNGIPGENPYVPRDHSADSFTPEPSDQSFLDHRPGTGDGSLDRNSASPSFRTPEGLSADAASSKQALAAARASLMRAQKDTQDAFMRYTSCLDIERQARQAVASAEKRRDDIMAILLSQNQNQNQQLNLLPETRSRKSSLSGDDRHSPPRYPLEEARHTVDPFMARVEKQMEWPSDGQGIYGSEAVPHLDDSMRSRKRQWDELQPHSNGYPCEVPVGTASYDSMGYRTDRHYDSQDIPGLPARKRMHHAMIPGFDVMTGTPLQTQNMPLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKI6</accession>
    <name>A0A9P6EKI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hinge domain of cleavage stimulation factor subunit 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_892502</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKI6"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cleavage stimulation factor subunit 2 hinge" evidence="5">
        <location>
            <begin position="79"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription termination and cleavage factor C-terminal" evidence="4">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="30481" checksum="DD556B6E01DFB5B9" modified="2023-09-13" version="1">MPVHHQLDHETALSAVRNLNGTDVGGRPLRIDLADSDPFLEGKTTVRGELLDGGYPGPSEPRARGSRSAANDPESFLANLPTGKPVAPGVSALDGISQTLASMPPNQLMEVLAQFKAFVITHPDQAKTLLVKHPQFSYALFQSLLLNKIVDSAILERMLASSRGPGGPPPVHAPPARPPVPAPPPHLQGYPPPHSAGYPPSFPPPQSNMYSLAAPVGPPAQPYYRPPAPAAVAAPPAAPAVPEIADKDRAMLMQVLSLTPEQINGLAEKDRTAIMALRNQFMGQLGTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL10</accession>
    <name>A0A9P6EL10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_849298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL10"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040547459" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="184"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="697" mass="74687" checksum="CD12693A40E062CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL22</accession>
    <name>A0A9P6EL22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_810399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL22"/>
    <dbReference type="OrthoDB" id="2856616at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="626" mass="71218" checksum="DC060C398E2284A4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL52</accession>
    <name>A0A9P6EL52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL52"/>
    <dbReference type="OrthoDB" id="3267861at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="8229" checksum="37ABD45622D678B3" modified="2023-09-13" version="1">MPAKRSFESNSNAGYSRSGGNTERSDELGSMARSNSESEPASLPSSEAGEVVEHISVGTVEWQNRGTLHVHLLLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELP3</accession>
    <name>A0A9P6ELP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELP3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="7062" checksum="1C9A54750D9F8E7D" modified="2023-09-13" version="1">MKIFLLANPPFSNRSCWKDGEYSVHSYSSLDAVCKSCTYLSLLHRASPLSYAQSISSIFHESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM31</accession>
    <name>A0A9P6EM31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_760848</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM31"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000084">
        <property type="entry name" value="GTP-binding elongation factor Tu family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000014">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="179"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="611" mass="66600" checksum="AE842F8655A2C171" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMC3</accession>
    <name>A0A9P6EMC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMC3"/>
    <dbReference type="OrthoDB" id="3121763at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="496" mass="56421" checksum="FBA94AEB9B73BBE5" modified="2023-09-13" version="1">MVKIYDILDALKKENSAKTITMRKRRKSNTIRECEKESCQSPSKITVSMPVRQTKTVERKANPNTIQKDSQNCEKAALLGPSVLRDEEFPAFPLDNVAATALVDVPLQSISHQSDEDQVMQDLLANQAAGDEDEEDPRNVVRRFLNRPTKTESENLIHSLIRDYLIEKSLYVPGRKITEGIVLPFPDPSDVNYYENRAGQGGGPTLSPALYAWDKPKRHSWNVRLARLLTSDFNSYLLHKGQAKSLKLIELHRLNNDNLDSDYSLLDSNSSELVDILKKLGEVEEIILNKLDATAQRFKKAATQRREYFGRGDGDSTGSLTLLITRELESKRVTNRRGERRRGLYIRRHMIIEEQVQKRGQDTTNWSLIQGAFAHLEDGDMSSDETETEKGFYASKVVRRRKKMWINPEVSSMLHFVDQHYNPRTASGTLKKGSAPLKREITHGSCNSVALPRPKLPFNIYNVKELGLETVRTLQPKEPIILPEIYSFDDPTSMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMI9</accession>
    <name>A0A9P6EMI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_87453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMI9"/>
    <dbReference type="OrthoDB" id="2978551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="698" mass="79114" checksum="1708829923B3F094" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EML4</accession>
    <name>A0A9P6EML4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromatin associated protein KTI12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_867959</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EML4"/>
    <dbReference type="OrthoDB" id="9972657at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="32690" checksum="E5216DAE7576D46D" modified="2023-09-13" version="1">MALITISGYPVSGKSTRSSQLSKYLEGKISEELYIGPFKSVTIVSDHSLGLSPTVYNDSTSEKPARGTIFTNLQRQLSVDSIVILDSLNYIKGFRYQIYCAAREIRLRTCTIHVVAPSELCQKWNSLRPIEEAYSKSTLENLIMRYEEPSSMVRWDAPLFTVLWSDNDIPGAQIWEAITSGNLKPPNAGTLSVAKAPTDALHVLEQTTNTMCSMIVAASSSQPEGGATSIIIGEAKVLVGLPPRIVTVSEMQRVKRQFVAIHKKAITLGTTERGGVHFGEANIARKFAEYIAEHIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMY8</accession>
    <name>A0A9P6EMY8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_75547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMY8"/>
    <dbReference type="OrthoDB" id="3040439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="427" mass="47825" checksum="F293F9A1B12FA108" modified="2023-09-13" version="1">MSPQSIPLSFLFSTPIIDRLMSSPKLPLDILTLVIDALAASCSDDESLSELMQSAALTCRAFVPLSQRHIFASVTIDNVNSRSKNPISPLEFANFFTEHPYLSEYIRELSINLPATTSQSESAGDIVENLFKAFLNIRSLEFLSINLGRRFSVTNWSNSPFSSAIQHLLRVPSLSRLHLSHLIEVPPDAIPTNLKHLLLESVDWKSIAETSSFDMLPPDLEVLTSNFSPSTTALLSLIRPDNRPVLLLKNLRRLEITGLSEEIFEICRMVASTSKVLTSIYLSVCTQAAFTGLYDAISPSLGTLRHLVLATADDYQSLDPYHCASEELEKIADSKIQCMTFQVSTGCDLECTTGDGWDLIDEVLTSEVNWPCLTEVRVEVKIWRFQRSKSAFDETMENLSKLYFKRLRASKCINFVYECHDVVVPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN99</accession>
    <name>A0A9P6EN99_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_587372</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN99"/>
    <dbReference type="OrthoDB" id="278325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1230.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001931">
        <property type="entry name" value="Ribosomal_eS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038579">
        <property type="entry name" value="Ribosomal_eS21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10442">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01249">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002148">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="9324" checksum="800B9EE68FE3C9F3" modified="2023-09-13" version="1">MENDAGVLVDLYVPRKCAATNRLITSKDHASVQISIVDVDANGRALNTTTSFALCGQVRSQGESDDSINRLATKAGLLRNVWQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENP2</accession>
    <name>A0A9P6ENP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoprotein TPR/MLP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_528676</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENP2"/>
    <dbReference type="OrthoDB" id="343070at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057974">
        <property type="entry name" value="NUA/TPR/MLP1-2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012929">
        <property type="entry name" value="Nucleoprot-TPR/MLP1-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057577">
        <property type="entry name" value="Nucleoprot-TPR/MLP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25481">
        <property type="entry name" value="Nucleoprot-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25785">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07926">
        <property type="entry name" value="TPR_MLP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoprotein TPR/MPL1" evidence="7">
        <location>
            <begin position="210"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="NUA/TPR/MLP1-2-like" evidence="8">
        <location>
            <begin position="515"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoprotein TPR/MLP1-2" evidence="6">
        <location>
            <begin position="1076"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="346"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1088"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="596"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="723"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="860"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1024"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1089"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1198" mass="136527" checksum="E714DE74E0D98E4E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENW6</accession>
    <name>A0A9P6ENW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENW6"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="469" mass="52632" checksum="DA9932105E8EE7BE" modified="2023-09-13" version="1">MPTLVTPPHVALYKPRSTSLIRRDDCQDERSTYEIIWSCLSTIFAVTWLAIHPNMPDPSSSWRWRTWSRVLIMCWAVIAPDLVVYCALNQFVAAREIGKVYKDRGWTTTHGFFLQMGGFRLLRLDGTSYPLWVDRFDELLKAGQVDFPNISKDEINDKSKGDVLAKGVAVLQTTWFIVQCIARGVKKLDVTTLEIFTVGFAALNAVMYFLWWDKPHNVEQAYMIPLKVLPAIPDPEGDKLLQAPSSNSGNPVASSTTAVAPIPALESYLEQSPRTVTPVSTPTSHPSTPPPEPLSTPHVSIRHAVGRNIYAFLSAIIRLIVNPYFWMATDHDMSDDKNYVGVFYAYNAGRSAFKFGIMLPITITYGAIHCAAWSFSFPTSAERVLWHVSSLVLVAVPFYFFVVLLFIGSFDEKPWVFQVAKLTGAFGLLMYVFARLILMVLAFVGLRRLDSIFPSSRVKPITGCFNAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPE0</accession>
    <name>A0A9P6EPE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPE0"/>
    <dbReference type="OrthoDB" id="3205748at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="452" mass="50496" checksum="A6CDCDAA2A12C009" modified="2023-09-13" version="1">MSLPLAARFRAIITGPLNTATPSIPDLQDDNEVYRGPKVHSGATKRKRDTNVSNPSSTRKVARRPSDDEGGTGRERTISFPDRNQLMQAMKDRFQEGPHVDFHGNYEVVDDASGHKARIQSVANEIWKATGYRFTVKDHPQFTNGHKTRFWCSQDEAHRSKSSRAARKAQGELYKPRQTSAGEVLAKNRFPCQSRLLVSSRDSTTLGRCVITVRMHHHVAHEPYLDLNLPPEIAQGGWGSGWFTRASTGAPSIPHDPNSPSMSAMDHLHTIEQPPPQEHTPPQQDSFDEIHHDIQELPQDLPTQPMIMSSPSIPEPSPPISLSQSAPPHAPTIDHNAPPDVYGRRMQAHIRNLREFCDGLEYQLQFNDYRMLHVLEREGGPFLELVADCLSKEGRLVPTEQSMDIPAPEMQPNTQQMMHNHNVAPDGVSIMQDMQMQAYDGNPGINPSALGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPJ3</accession>
    <name>A0A9P6EPJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_485385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPJ3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="14855" checksum="3DDF6F48A6A5E6B0" modified="2023-09-13" version="1">MVPSFIRSGLGVWSSFFTFLPSITDFGFSYPPAVATLRRARIQTITPALLPVTLFFIYLFHSFHITSSFRLEMTCLLILYLLYNSNNRPTFGSNIECSLSESPNLGGCESYHRYCSIMRTTLYCTDTPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPV5</accession>
    <name>A0A9P6EPV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RWD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_806626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPV5"/>
    <dbReference type="OrthoDB" id="277175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="25602" checksum="DEA6B76A6EEF4B42" modified="2023-09-13" version="1">MKFLKVLESIYPTEIHKISETDIEIDAEADELPDGADNITLTLAVHYPEAYPDELPELSLKHEEEMVTEEDEEKLIENLLRVGAENLGMAMTFTLVSYLREAIGALIKEKIQIERKQEKRTRGTPVTLESFRAWKAKFDKELSIKKAQEEEEKLKGLTAKEREEFKRSLIRLSGRQLFERNKNLDDETLVEEGTVSVDFSQYERVQEEEKEEEGLTFSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ58</accession>
    <name>A0A9P6EQ58_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_844923</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ58"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="21012" checksum="8D670A6134A7030C" modified="2023-09-13" version="1">MAPTHSRNSSFSQSSVGSGPSSGWVTDELSDGFSAPSTPFFTPGSTYSELQSDRSPSSMSSVLPSRLSPSQRKQARDVKAAAKYLAELEKSHKQAALPKLPKERTEKNQEASEARRSNKSTIVACPVPECGETYTRLTGLKDHLAKHFPMRRRTTLQCPYTGCSYKTDTKSSMTRHQNLKRHFKSITPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERX3</accession>
    <name>A0A9P6ERX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_803814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERX3"/>
    <dbReference type="OrthoDB" id="3363286at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="48325" checksum="3E92BD38B5B13C26" modified="2023-09-13" version="1">MPRLLPRLAKEIEKQGNGFLKCYPITFAKKKRVTKSLYKAPHPKPSFHPSNYEKSILLGSNSPVTFSKDYSHHKRLPPSVSSQPSLPRDGDAPRQMSQVEFSWWANPYLRMLASPIRTCIATGATLPSDLLIRLVGLRVETPIVLGPKKEVVPATLAPDGILHPKYVSRRSGGNAIYALCWRKAIEDLQKGPFKRISAHLKYPHHLPDQVAHLLRLRVLQELELVTERLEWATRSGRNLANDAVVLRRLSREEWGLMKTTKTIPYQSAIAVLILPPPNKDPVTKKRPQPSMSALPPTDEDRPENLPPLSELLSISSDTFPDETGMLPRPEVPLYHSITAFPSRSQRAALHIFLTRILTAERHLKRLHNEKNGDKSVIPAEKFEAFSVNKSSHAFLLCSDAKTVQRGDTAAVAKALWRLRMYESEGWSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERZ4</accession>
    <name>A0A9P6ERZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_756629</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERZ4"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="6962" checksum="568126EC97F4819D" modified="2023-09-13" version="1" fragment="single">NSCNTGPVQCCNTVKDNDAQTANLIHDLFGFNTPINGKVGFRCSSISGTGAGSTWCKLCYSTCLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESG9</accession>
    <name>A0A9P6ESG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_844069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESG9"/>
    <dbReference type="OrthoDB" id="958254at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040231805" evidence="6">
        <location>
            <begin position="20"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="25585" checksum="637954D77FFE1D46" modified="2023-09-13" version="1">MRLPALLLLVLSGLAGVLCTRRSRLALVDTDGDAQNFMQSKLVVPVQLGVMSRCPDALTCEAVFNDVLPSVKDKIDLSLVYIAKFDPTDTPFGVQCMHGRWECAGNVQQLCVHKYASVATWWEFVSCQNKQGRSRIGFPDVALQCAKEVGVDWEKSGAGTCAGLDGSGTAPEGVALLKESIQTGISLHLKSSCTVVINGKAVCIHDSEWKNCENGHEPADFIKQIEEEYSRLNGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESU4</accession>
    <name>A0A9P6ESU4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plectin/S10 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_902694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESU4"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="149" mass="16855" checksum="4CD01770E8A7333E" modified="2023-09-13" version="1">MIIPKQNRRIIYENLFKEGVLVAKKDFNAPKHEELDVPNLQVIKALQSLTSKGFVKTQFSWQWYYYVLTPEGVEYLREWLHLPAEIVPATHKKAARPPRPAQVRPGGGGEGAYRAPRGGDRDGYRKKEEGAPGEFRPQFAGVGRGGPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUB4</accession>
    <name>A0A9P6EUB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUB4"/>
    <dbReference type="OrthoDB" id="3245714at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="382" mass="41326" checksum="900C6B8727F88F14" modified="2023-09-13" version="1">MRPLVARAYVSTRKRPYSFAWVVIVANVTPSPCLGSYTLHSCQRYKSPVFQHLIEPPSRLERSNMPSVKSRANKAAIAARVAAYNASLAALEEEARANGNDAVDVNDINPVADMQGVQANGNRKVISTPMPLKPTLPSMLNLNTPPNLNRALSVGAVLTQRPIKATGSDEENVPIASKTEVVGHNGDNTDANRQSLASPSIGGKERDLRAFEIARQRAKRAEELEKRKAKKVKEVVVTAVNGQGHNRGTSESGVTLGQGISRKKSNREMDEDLEEAKMPSVRKGGVGLSSCGGAGVQSSNAAAMEVSLSDLIVPSHRKPRKVKEEDYEFISPVRSVIILDDMFETKEMDLDEPWEHIDSAVEFGIPSKEGDFSYAAVLASGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUH2</accession>
    <name>A0A9P6EUH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_843497</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUH2"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006288">
        <property type="entry name" value="TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01384">
        <property type="entry name" value="TFS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="14">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="11">
        <location>
            <begin position="5"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9535107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="12333" checksum="74052D291D97D6A7" modified="2023-09-13" version="1">MMLFCPTCANLLVISSDSGLNKWACNTCPYEFPITKQMTSRTRLKRKEIDDVLGGDEAWAHADKTQASCDKCNFNEAYFYQLQIRSADEPMTTFYRCASCAHQWREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV08</accession>
    <name>A0A9P6EV08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial ribosomal subunit protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_754247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV08"/>
    <dbReference type="OrthoDB" id="283424at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039848">
        <property type="entry name" value="Ribosomal_mS35_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="2">
        <location>
            <begin position="112"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="30623" checksum="21D2EB862A99987E" modified="2023-09-13" version="1">MFGQTLGRTLTASRCARSVTASKLTRVQHFSTSSALLRRQEDRPEAGAASKRRTNSLLEDDAEDLWDAIDEPADVEDSPSSGHILIQMQRELLQYMRLIEHEIPKLVAYRKPFVPPTDDQPVILRSMHYQGEPHPATGKRVVVVPVDKLPLKNETALHKFILLAGPRWTPTPPADAGVSPLDSWGNGYIKISCEDFPKPSQNLKWASDTLDKLITEANDGKDTFADVPLDMRHIFAKVKKQKKGDHLGNRVFHRPSVRDFPQEWLPEPQPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI14</accession>
    <name>A0A9P6JI14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_911611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157976">
        <property type="protein sequence ID" value="KAF9521897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI14"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="16154" checksum="975AAC4BCA31912F" modified="2023-09-13" version="1">MSVGGATPPTYVLGPEPLPRFIHHISANIFIMGASVVIDGSNIKNKTEHTIWLIRMDGTKIAEIAEGKTEYLSKKLIDRFRISFDNDSNAWVVKGNETWEIPEGAEIELWQVDEEDGQVLEVTSIVKGDKQERKCEAYQPPKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIM9</accession>
    <name>A0A9P6JIM9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIM9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="146" mass="16454" checksum="9B9008682E3BC78E" modified="2023-09-13" version="1">MPSTLVAPHLALPDFGQAFNPEDLATKLQNVNDKRLELASLGLAPFLQALSRSGIRRRRSEANGRSYENQNPTLSRSYVPFVPPLGQIDDALQRFHQYFEFIRIAGFALTVYRFIEDYLNVLGLIWHPQCLCSPVTESKHVKAAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKJ5</accession>
    <name>A0A9P6JKJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKJ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="308" mass="34590" checksum="A6B199C2032B0C1A" modified="2023-09-13" version="1">MTRLVEPTLNELVGLGWQDPLDEFFPTTFASSSTTYIPLSPPPPPPPFFPSLSPSSPSIDRIRMEDLEKPKGRLSRRALSSPYPRRSPRASEKSRPFGPQFVNSEMFLFKYWSEENFFQNDESNSDRTAITTSTGRTRSERRTYFRKDDRWVDPWYIAANQRPPWWRRANYKHRGINWQEVDPSGRMPLHWMKQYGIEQEANETATSLVVSPSTSSANATPRALAITVPSLTNSSSSQPILTPSSSAAIIVGPSEPSQKQKVVVTSREAAGKTSSAALDIRKVAASNARMVAIKQLRRESSNEKIAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKQ1</accession>
    <name>A0A9P6JKQ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apurinic-apyrimidinic endonuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_861213</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKQ1"/>
    <dbReference type="OrthoDB" id="7663182at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.150:FF:000001">
        <property type="entry name" value="Probable endonuclease 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002199">
        <property type="entry name" value="PRK01060.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445:SF0">
        <property type="entry name" value="APURINIC-APYRIMIDINIC ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00729">
        <property type="entry name" value="AP_NUCLEASE_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="10">
        <location>
            <begin position="108"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="403"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9524477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="49485" checksum="3A473B09222C8CBB" modified="2023-09-13" version="1">MSKSGRITRSLSKFQALTTTETWVSTSESRPSKRIKWSEEASDSFHNTQSLVKADDGVAPGTPPNRRGKRKVTDAISDRTQFLPRLDIPWKIGAHVSAAGGVEKSVINAATIGANAFALFLKSQRKWTSPPLSDHSITEFKKNMKEYGYESRHVIPHGSYLINLGNPDLQKREKSYECFLDDLQRCEALGLEMYNFHPGSTVGAATLEDSITFISGSINRAHRETRNVTVLLENMAGAGNIIGGDFAHLAKIIAKIDDKKRVGVCFDTCHAFAAGCDIRTKEGWNSTMDEFSDTIGLPYLRAFHLNDSMCGLNSRKDRHQSIGQGELGLLAFQHIVTDKRTRDIPMVLETPSFEMPKEVWGVEISVLGSLCTSTGKETDLSVEATEGNQLEILEERIRVAVKAAEAKNGKSKGRKLTAKRKPGDKKRKRPVDEDDASDTEEGSLCSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL36</accession>
    <name>A0A9P6JL36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_773884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL36"/>
    <dbReference type="OrthoDB" id="417877at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="7"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="317"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="451" mass="50511" checksum="2F992043CB6097E9" modified="2023-09-13" version="1">MSSCTRFKVAICGGGIGGLVTAVALSKYPGIEVEIYETAHKLTELGAGIGLFSRPWEVIRRLGLEPELLQFTEVKPTDGPVTAFRYRKSDRPTGVEFYTLKTQGHLMTFHRPDFQKVLLSHLPASYQIHCSKRLRSYYQRNGHPITLLFEDGTEATCDVLLGADGLKSAVRRSLLGEKVHRAQKEERWTDAADLTALIEPSWSGTNAYRALVPGDMLRSKHPNHRVLTQPTQYLGKNGYIIAYPISKGKYVNVVAFKSQHELEGSKFDGSWVCPVDKSEYVRMFEGWEPEVLSLLECVEKPLRWAIHCVKPLPTTVSGHVALLGDAAHATVPHQGSGAGSAIEDAYMLATVLGHPTTTQANISRSLSIYDRIRRPFSHRVQERAKLNGLYFTFSCLEIKFDQVPEDKLLSKLKLLGQVFTKNWEWSWTTSIEPSVQEALKLLDEDPSETNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLL2</accession>
    <name>A0A9P6JLL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heat shock 70 kDa protein 12A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_871039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLL2"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="64280" checksum="2A6D41C3BD469FF6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMI7</accession>
    <name>A0A9P6JMI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMI7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="209" mass="23267" checksum="E16498FC6E3EE070" modified="2023-09-13" version="1">MSKKLHGFGRVRQLELSSIEFPVQFFQAVAKLPHLEPFFTFDIFFSLPISLNPLVASQIFATLNHQPLDDHCPTHQNSSFFFEFLTLCPVLEEIAIENISQLEHIISVDIPVRASVAPQLSSFQGPPFLAAVLTPSRPITSITIFGDIHSPVPRMVNLLTSLSLGSAPLTKLDLDYVPLLERALRRSPASSQTLDFSLSISRTRARSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMZ3</accession>
    <name>A0A9P6JMZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_442395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMZ3"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="30218" checksum="3E340F8B0180ED12" modified="2023-09-13" version="1">MADHSSFALIGGHILAGCLAVTIWDILCFFKADIALVSLHRFTWKTAIFLVARLTPLGYLITITIFTVEINLDCDTLQHTFRTLLVFVKPSTTLLLLFRVDAVYNQNMYMRFFLAAIWLATLGAFMLLAVVGIAPAEAFPYCFAVTMPALIMPVAILQIASDTFCCLAILYNLGGSSWKERMVSLKKVVRPNHSHLTDVFVQDTIISSILALFANVITGISCALFVPPFYSGDVAFMASHPVGKSTNCRSVPAQHFRLIRVQNFLSVASNERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNM8</accession>
    <name>A0A9P6JNM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Pyruvate decarboxylase THI3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_836515</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNM8"/>
    <dbReference type="OrthoDB" id="3970464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004737">
        <property type="term" value="F:pyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000949">
        <property type="term" value="P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02005">
        <property type="entry name" value="TPP_PDC_IPDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07038">
        <property type="entry name" value="TPP_PYR_PDC_IPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000019">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000024">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="PDC/IPDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047214">
        <property type="entry name" value="TPP_PDC_IPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047213">
        <property type="entry name" value="TPP_PYR_PDC_IPDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452:SF30">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE ISOZYME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="14">
        <location>
            <begin position="32"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="12">
        <location>
            <begin position="246"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="13">
        <location>
            <begin position="440"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9527537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="591" mass="65152" checksum="F6E05C5C3BA21AC8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNM9</accession>
    <name>A0A9P6JNM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNM9"/>
    <dbReference type="OrthoDB" id="3027018at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="677" mass="77222" checksum="96103EDE233A08B1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNQ7</accession>
    <name>A0A9P6JNQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_837032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNQ7"/>
    <dbReference type="OrthoDB" id="3061721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="397" mass="44298" checksum="B9079BEA9A8ED5CB" modified="2023-09-13" version="1">MAHINGSNGLNLLARVKFHEGSFVKLVEREPPAQLGVMHYNRLPFELEREIFEIAASAYPKCVPIIIRLARRFQKWFEPELYRILRTGEDNVIRPPFLYHNRDPKGVSLQRPLQPPVHTLMNTHNLGLNTDRLTTYGPWVRNILIQNRPSLEIKSILEHCPNVTNLAIWIIHGNCDILLPILTKLADGGNGKLRKLSFDPSYFFHDYRSEMPIPFSLPSFASLTHLEIINATPSWMKWSELAKMPKLTHLGLTGVVHAPLIKGVLKECLKLEVFVIFDLDVRFVVGQDPGAQNAAVPTTVGNDNTNSGNQITVVSGAAAPATPGTPSGGNEGAQNDEEDWRTDCRVVMLKSVKDHLDHWEMGAKGGSDFWVIAEKMRNSRRASIRAANAAKASSSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP30</accession>
    <name>A0A9P6JP30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_856608</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP30"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="40106" checksum="B1330A6FE9BC9207" modified="2023-09-13" version="1">MSSQNVVIVGAGPAGLISYNTLAAKAAKASNFDVILIDPRNFHVHQPSSLRMLVTDQGALEKRTLMPHNEALQNGKNKRVVHDKVVSITDKGTQGGHVTLASGETIDYSVLVLSTGSVWSGPLVWADTKEEIIAKAHDWRSKFKTSKNIVLVGGGAVGFELAGEIKDIYPNTNVTIVHTQLLPLNDTYTDSWRKLAKKGAEKRGINLVLGDAVEDFEIQNGKVTTRNGKSITTDLVVPTFGSKPNTEIFKTLGADALNESGFVRVQPTLQLVNHPRIFAAGDVIEWKEEKQLMKAMAHAPIIAQNVLAMVNGTNKLKPYKTSMEMIVLTNGKGGGSGFMGAMGGVALGDWFARMIKSKDLLIDMSKKAYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP74</accession>
    <name>A0A9P6JP74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_884308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP74"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="275" mass="30770" checksum="3BC29D93CF92D477" modified="2023-09-13" version="1">MSNYPVPPPSYKPSSPKKYHATDDSREPLLGGASSSAGGYHDQPSAGDLPDDFKYGVSVSESSPEIRNAFIRKVYTILLFQLAATAIVGGVISRSPSTISWVQTHVWSFYIPLFGTLINLGLLFWKRHSHPWNFVLLSTFTLMEAFTLGVAISFYNQTIVLQALLITIGIFLGLTLFTFQSKYDFSGMGPFLFGSLIALTMAGFVSWFLPFNRTFDLIMAIGGTLIFSGYIVYDTYIINKRLSPDEYIMGAISLYLDFINLFLQILRLLNDLQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPB8</accession>
    <name>A0A9P6JPB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="3 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_792299</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 14"/>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPB8"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
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    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
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        <property type="term" value="C:nuclear pre-replicative complex"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0043596">
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        <property type="term" value="F:ATP binding"/>
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    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
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    <dbReference type="GO" id="GO:1902969">
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    <dbReference type="GO" id="GO:0006279">
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        <property type="entry name" value="DNA helicase"/>
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        <property type="entry name" value="DNA helicase"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
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    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
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    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MCM"/>
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        <property type="entry name" value="MCM6"/>
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    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
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    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
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    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
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    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
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    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
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    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
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    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
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    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="443"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="765"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="784"/>
            <end position="797"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="824"/>
            <end position="837"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9528016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="963" mass="106280" checksum="B676700E3667D129" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPK6</accession>
    <name>A0A9P6JPK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_853961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="71"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="79"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="385"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="770"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="820"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="881"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1032"/>
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    </feature>
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        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="509"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="529"/>
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    </feature>
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        <location>
            <begin position="588"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="639"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <begin position="697"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="772"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="884"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1084" mass="118730" checksum="7D4806CD80AB3A8A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPX8</accession>
    <name>A0A9P6JPX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPX8"/>
    <dbReference type="OrthoDB" id="3204502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="307" mass="33846" checksum="AECC67CCCEE5E4D4" modified="2023-09-13" version="1">MPHSRPRPILKALPSPTMTSTSPLPFASSTHVYPQDSPHVHFPPTPTMTQTAITHSSFMYDRKPIMVLPNSCALPERGERELDIVSPIGSDHGDAKAWPGRCSTQSKLKGGYFHPSAYEAAEYEAQDQLPSSSSLLFDQEGSLPSTPAQQYTPSSSFFKRRSESPARKPQSTPHSRLVPPPLVFDSSESSDCSELGSPPEIPNQPNFSVAFTHPYHFAQHIPDVNLNFLNPLETSPRFKRRPTHDRKTSETDREGFRLPKEGKTKPRTRNCSTSPLERTRKAAANVACVGFSTSFSDPALEGCLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ28</accession>
    <name>A0A9P6JQ28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_766940</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ28"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000761">
        <property type="entry name" value="Zinc finger protein 449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9528438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="14915" checksum="CD97C679E5FB4F24" modified="2023-09-13" version="1" fragment="single">MGTLSVESSTRTASGPLSDEESESVPAAKKRKKSKMHECDVCQKKFPRPSGLKTHMNTHNNERPFACGFPGCARTFGVRSNAKRHLRTHGVIPQSSTGSPPYVVDFSTPVVLQNENSGRGRQFKLRWMPPSSTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR36</accession>
    <name>A0A9P6JR36_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR36"/>
    <dbReference type="OrthoDB" id="10044044at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF1">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="52"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="202" mass="23600" checksum="34CB633DDD89CE00" modified="2023-09-13" version="1">MSISKLWTLTRPAFALVSRRTMSTPTSDTNTTDAPLFASPQEERKWNQLSAQMSNFHNYFKQEFNQLYKLADGSYERRGLSLTDYLDTARSLDHHLTMHHTIEERFFFPRLAKKLPQFDKNSQDRAHLESHEGIHQGLVNLMALVSKFEEDQTSYSPVEMRACLDSFRDVLFNHLDEEVEDLKGSNLKKHFTLQEFNGLLMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRN8</accession>
    <name>A0A9P6JRN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRN8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="15504" checksum="CDD5519567BA6E67" modified="2023-09-13" version="1">MRVVGLCSSGFGMSSVFCFELIADGFSCLLYLPLLMCLTMTMTAPLVIVIGIDCTRARIRTRTCGLDSYGCPSTFTRTLLHHTTPPCSFVRSMLHRCLPSFRFASRGCVRPSLVSMTFMLYHQLYGRIHSLHARPSLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSZ2</accession>
    <name>A0A9P6JSZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_809100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSZ2"/>
    <dbReference type="OrthoDB" id="2410195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="405"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="711"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="815"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="731"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="815"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="846"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="865"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="886"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="909"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="938"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="952"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1026" mass="110888" checksum="5B138A912E50577E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTN3</accession>
    <name>A0A9P6JTN3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_808413</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTN3"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03700">
        <property type="entry name" value="EF2_snRNP_like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="17"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="841" mass="93057" checksum="5E718D8BA591EEBE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTT9</accession>
    <name>A0A9P6JTT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="10">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Biosynthesis of nicotinic acid protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BNA4</name>
        <name evidence="13" type="ORF">CPB83DRAFT_847544</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="10"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTT9"/>
    <dbReference type="OrthoDB" id="10053569at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070189">
        <property type="term" value="P:kynurenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000129">
        <property type="entry name" value="Kynurenine 3-monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0274">FAD</keyword>
    <keyword evidence="2 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 10" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="470"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="10"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9532263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="500" mass="56169" checksum="5EBC0473964A6549" modified="2023-09-13" version="1">MHPPQLSSRKVVVVGAGPVGCLCALALARRGWSVEIFEGRADMRIPAVKAAVKQRSINLAISHRGIAALEAIDPAAAQRFLQDAIPMHGRMIHKLSGDLDSQLYDRDGQCINSIDRALLNEGLLDEVDSSINTRVFFNHKVIAADFDTQKMLVRDSASNKEFSIDFDFCVGADGSYSIIRRQLMRVVRMNYQQEYIKDEYVELKMPAGRDANGEPTFLLDEHHLHIWPRRSFMLIALPNKDKTFTCTLFAPSVELDRLHTPDETLAWFSRYFPDAVRLIGDKTLVNDFLKNPRCPLICTKANPYHYKDRAIILGDAAHSMVPFYGQGLNAGLEDVRVLATILDQEAVSAAPTSDGHDRRLANALQRYSETRHKDLIAITELAMDNYIEMRHKVTQGSYIVQKFLDNVLYSLTSSNMLSLASLTPTLSQRPYPSGRPRGWLPLYTMVTFRPDINYATVKQKAARQSTILSMLLWFGIGALGAAAAWLMWATGNILVNYLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU56</accession>
    <name>A0A9P6JU56_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_758151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU56"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="224" mass="25555" checksum="104284C8CC6DB47D" modified="2023-09-13" version="1">MPGIPKAPVPASTPVASRSRRQRVLKEKPETAAPKTLARVSVKESHGLYAFFRRVSGDNLTGEDRYETIETPEAMRIISGRPWESAELRLKSFKDLHTLWYVAAREQNLLATQKEETRRMGVTNPEMQVSLDKVRNCRKTMARIKMVLNERRLAFEGAVKLAGKQRENTNGNEDNTEIIAFMNELTREEDPKTKQFRAQRRNHASGQKVSIPSKETAEEEIFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV50</accession>
    <name>A0A9P6JV50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_319522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV50"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="61" mass="7022" checksum="1BAC20B29F356E42" modified="2023-09-13" version="1">MEKLSVFAIVHGLGLSFLLILISLFNLCQTTTHSPMIYMTFLRSMKFAKSRITSVISLRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVA7</accession>
    <name>A0A9P6JVA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVA7"/>
    <dbReference type="OrthoDB" id="3229989at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="148" mass="16498" checksum="7E5150C4537D2066" modified="2023-09-13" version="1">MLDKYLAPTTPEATANNHLTENWPSWTTDQPSVDEALISGCASYRAFDRYIGGKDLFLLPRTRSELESVLRRYAYDAIHNAIAISRSPLQTGGYSRVCNLAEKSIRAVLNTADNADNLLELHRPHSAKINHDMDDCACKNHSRPILSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVU3</accession>
    <name>A0A9P6JVU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">CPB83DRAFT_842445</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVU3"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30694" checksum="4DC982929BFAFC35" modified="2023-09-13" version="1">MLLSHRVLRTVSEVIYALLFLIIVVAAGLSCAAIISQAVRTSSTQDWVKNFNALIVGASYIILLAVSLLFCVKRRVAVRLKLSRISKTYRTVGKGDLPNSVHTYVTQEYVRTCLVCYESLPKDVYHEGWGRPGTKYSGIRFKRALLDTIPQIDKLAHIIIPLHPALKPHARMIHHFRFIAPLLPKDEDGMTPLHYYDSAIQLVRNSSREVGEREFEVGMLAAERIVGCLEECRDEMRMGGDEFSVGDDEDEEGDWEDRDDRTKLDEALCSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVX1</accession>
    <name>A0A9P6JVX1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_843172</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BCD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVX1"/>
    <dbReference type="OrthoDB" id="272357at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23023">
        <property type="entry name" value="zf-HIT_BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057721">
        <property type="entry name" value="BCD1_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF11">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25790">
        <property type="entry name" value="BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="8">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="344"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="431"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="461" mass="51428" checksum="EEF7B3073828B896" modified="2023-09-13" version="1">METKPAKRLQLPTKPDFTEHSDVLSTELSSEPLVASSSTQLLCGSCNLLPAKYTCPGCRIRTCSLPCSKRHKENTGCTGKRNRAVYVPMNEYTYGRMVDDYAYLEEVGRKVGEWGDEIVKGGYTNPGTTGAGGGGNYKGRMRGRGRGRGVFHGGQGQSRRDVLKLELEEMKIDMDLLPQGMEKRKLNQSTWDPKTRTGYLTIEFKIYKPKDSFAPASMSADPPFTLLTHRNTIDKGLLTSLRNCLNGLGSKSKNQSSAYPDWVRRLVFSSDDGNGAEDFTNPHFIVLTRFDHLNSSNFEKPKYAYQVLDPTQPLSITLQHTHFVEYPTIEVWEELDKTIVDKEGNLQQEEESQRPKRRKMNVKAGKKAISGLIGAYGSSSEDEEKIPEDESESHQQNGLAALGDYSGSEDEKEIEPAALLELMRKAQAGGDSWALEGNEDEVVDWGDIDGEENEEETDSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW47</accession>
    <name>A0A9P6JW47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW47"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="62"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="500" mass="57149" checksum="B0A26D9841ED67FF" modified="2023-09-13" version="1">MDSILHHLENTNNAPTTQQQAWLESERLLLRSKKIVLEQEMAEFRLQFAAIERQCNQYTRVLSPIRRFPNEILLEIFNKLSSSDHRSVLSVSQVCHGWREVIHDIHSLWTEVTIPLPGHRNQPKDVYQFLQQVEHYALYAGGTPISLTIGNISESIVDSLLYEIFEEDSDGLSVPVCWSHMSIYTTKLLNFSRLALGHYEALGRDTTDLTSLAITASIFDDIYAGLEDVLDLTQFPELRSFRFDIRNPSSLDNRVLINWNILTFLTLRSRKSCVEYLEIISRCPALETLDITPDVIEEDLVQGPLVTLAKLRKLIITTEYQPITIIERLLCPALEDVAFTFGGFTGINDLSITHFLERLSAGRLHRLQCSGDALFAFLEKRDKIPSLLSLKVTAPFGEVEGGLSSIFNELTQAYDDEHRFFNLLEEMEFQDYPPFSPGGMMSCATMIESHIMGSETHPEAKNPRLRFVFTYTERPQLNEPTNLIHILTRYQEMGILSGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW70</accession>
    <name>A0A9P6JW70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_866135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW70"/>
    <dbReference type="OrthoDB" id="10037289at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="255" mass="29610" checksum="CDB27218BC1D1A22" modified="2023-09-13" version="1">MDMAEKRDPDAHGMYIYNDFYAYAILDLIDTTLTSLHTKVVTKKWKDAFSILEALVMFASYEDIWTQCDDGQRAVHTFKALGSLCVTLLRKIDEADELDPEHYPSLESVLKNMVDFCRSFKDLSGKYGHVCKAIARRIFKDKSPADYKLEITRLQEWAAGLEDKEMKKTIQAEIKKMTKNKAGSKAKTAWYSTGEVIDENDNRPDFKFTGVWKRYRDYLSECPRVPLRGPPEWDLTEWTKAEREPYSFDSMGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWD7</accession>
    <name>A0A9P6JWD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_756426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWD7"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="9164" checksum="3C2C3338417200A6" modified="2023-09-13" version="1" fragment="single">VLKYGKGLCGEISITAGDVDRLSDSKWLNDNLIELVTKIHLRFWANKLGNLNPALRLNIHIFNSFLYTKFSRCIKISSGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWG2</accession>
    <name>A0A9P6JWG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BOD1/SHG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_843301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWG2"/>
    <dbReference type="OrthoDB" id="5579731at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055264">
        <property type="entry name" value="BOD1/SHG1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05205">
        <property type="entry name" value="COMPASS-Shg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BOD1/SHG1" evidence="2">
        <location>
            <begin position="9"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="24703" checksum="8C976225CBDFC51F" modified="2023-09-13" version="1">MPIETPAALVEEFKKSGEFDRIRRELLQEFQKDDSYTAFQGKIEEIVKQRLAKAQMLHYLPQDMVQKELGQEVERYPIVERAVADVQLFSDPTFIGKLGDSLQKVLQTANEKSSAPATQQMTEPEKDILVPPAETTPSIENTTITAPSPTLIDAAPVIPRIPSPGPPPTPDQPPLESTQSLSIDATKDTPATVDGALDAPQTSADPNFEDAGPRPSSNNDMVVDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBJ8</accession>
    <name>A0A9P6BBJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_348782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158128">
        <property type="protein sequence ID" value="KAF9521323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBJ8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="131" mass="14606" checksum="DC8BF10428775969" modified="2023-09-13" version="1">MTRYVFPMDLMRGSDAYLPLQNGESRTAERVKHVEEDLWWKPQDYGASTSRHADSCFATHLYAKLRCTRSVSSGRTLQRLCPKEAVSSIATSAHGPVLVTGTKPHTVHPNIAVDCWTNVNPTGFNAIDDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E485</accession>
    <name>A0A9P6E485_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157953">
        <property type="protein sequence ID" value="KAF9522261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E485"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="22678" checksum="0FE6E4BEC50309EA" modified="2023-09-13" version="1">MNLITNEQACKRTPCTIGTTGDLQELQEQQNAVLVKSFAMYLSGERTVSSKFVIGEMPHVGLKGNSAKKDFQGVGKTSLPEVHPRPKYIGWWWISMIPHLIINLASGLLFPLQCWCDSSVEGCNIGESSEVGEEVEIGDSTKVEEVIKADGCKTGIESGALRQKTGIDDVKNINSRASMTIIDILIRDYRRRSGTLIRNQHNVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4F2</accession>
    <name>A0A9P6E4F2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4F2"/>
    <dbReference type="OrthoDB" id="3054765at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="55208" checksum="21DD2EE687492AC3" modified="2023-09-13" version="1">MNFIDQLPVDLITGIFSLICQPTEFHKDVIGYTPPFYLGTICRSWRNLAWSTPLLWTYIYLKVSSKPSNIQAELLKDCFARSGSSLLSIVFRLENENFSWDPRTTYGSKPFTERLLRLIATECARWKTLEVDIPNEGCADALGPTTLHAPHLQKLRIRICQNHLSAFFVEQRGELSHFFLEGAVGMTVHLPNRIPEVWKSITTIHLDNAVFVEDIIAILVASHQTLRHFHIHRLGTFSDESLPPAIAAEAEFPHIESLILDGGSRNQLLSIFPIFLSAPKLRKLGIKMPKRMKPADLQLFLDQMGVSLEVLRVRLRWIEDDGEFGRVQAEALIKLLSQHSKTLREFALIIQEFNRASDRFFDIFHRSLHCNGYIANGSVSGPTLLPLLKSYDFDPGFTTGPWDPEPEHAQPAVLSALQMVQSRWRNSFHWVTERSFKLNLHDENRMWVLDYLKEEVREGLQVNFTEFLLGSPPLDNWCFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E535</accession>
    <name>A0A9P6E535_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_89661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E535"/>
    <dbReference type="OrthoDB" id="3357519at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="58255" checksum="92BF4E4965DE83FD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5M5</accession>
    <name>A0A9P6E5M5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_732805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5M5"/>
    <dbReference type="OrthoDB" id="2970937at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="18889" checksum="72AC9694EB35678A" modified="2023-09-13" version="1" fragment="single">SIEAQLIPLLVAPFLAAYPTLPHTPTIFIDGLDECDTPAAQRSVLKMIADVVSIHRLPLRFVVASRPEVHITHCFKAPPLFSITRAFGLDDDFESMVIYFRHEFNRILETRSDDMAIVPKPWPSYKIIRDLVRRASGQYLFASTVIRFVGDEYDHPVEQLQVLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5N2</accession>
    <name>A0A9P6E5N2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_863709</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5N2"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000409">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000076">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="43"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="576"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="585"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="684" mass="75701" checksum="772B9096A0E6E37B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5S0</accession>
    <name>A0A9P6E5S0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_910976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5S0"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF9">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="37446" checksum="6ACD364373B0E641" modified="2023-09-13" version="1">MSKISDHKILIFDVYGTLADWETGLFDALQPLLKKYSASRSWSRKDSLTAFSSVETDLQAQYPTMLYSDLLVKSHEVLEERLKALATANPAAGGGTGSTLAGDVAPSEAEATSSEGAGSSAAANDLSTDSSAPARVGTDAHKAFGSSIREWPIFADTSDALHRLSKHFKLVVLSNVDRESFKYTHALLSEGLVHADLTQEILKSYTYPDPNPNRFWHPQETTPKSRSPFTLILTAQDTGCYKPATGGFTTALQYLSSQSTLTGNLSISSNDADGIKSKVLVVAQSLTHDHEPAHQLGIKSVWIDRPGAVTCNERPGGSDAKTKWTWRFDTLGAMADELESETASSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E765</accession>
    <name>A0A9P6E765_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cyclophilin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_821326</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E765"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="40"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="277"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9523614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="527" mass="57014" checksum="E46F9390FA9066E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E795</accession>
    <name>A0A9P6E795_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E795"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="98" mass="11098" checksum="9C410487BD9157B2" modified="2023-09-13" version="1">MLLNEAWDGLRIFSINRNSSNIEGNVYVQGRSGSNPSRMSLCQNTNDNTRTIFQVIKKTADGFFKLQAHQTGKFVQHRSDLVYAEGNRRAPLKTVPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8B9</accession>
    <name>A0A9P6E8B9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_886285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8B9"/>
    <dbReference type="OrthoDB" id="3066463at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="36954" checksum="AB9E15B24FE47AE8" modified="2023-09-13" version="1">MLFGFGLGSVDDPHYEIWLIHFVRFNGVAAFSVVAYDTLSTCFDEIQYIWTQPLKSPTKWVYLMTRYFSLLMQIQITVMTLTLTPELYDVATCRKLFYLRALSGGLLMHCIQCQLMLRAYALFIHARRIAVAFIAFFVAEVAAGPTLIHFADEVSLAQTGSNGMLCIRKIRILDLWLFGVSCTGPHLIIIGVTIFKFLKELPAGWGRIPIVLRVVKDDVSLVLLIISLVTSISIAARFNSMYAYVGFNWLIALVPSMSCRNILSMQKLRLSGCLRGHPNQACSCQPSRAPQLTSFVFESLSTSQSVVVDRLSVLDEFSKSRPKGKKVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8H8</accession>
    <name>A0A9P6E8H8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_820210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8H8"/>
    <dbReference type="OrthoDB" id="5345779at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="572" mass="63786" checksum="3E02B464999BFCDE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8T5</accession>
    <name>A0A9P6E8T5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8T5"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="168" mass="18453" checksum="976DA34813639FF9" modified="2023-09-13" version="1">MSRKAETGKPEVWTVPVSSDGESGPDTGGNVAKAEAILLNGTLEKADAERRLLLAIEAREKGIKGTMLDQKTWTKASTRAGRIVKIGKGRAKESADNLALAILFALYNNKHQLASVYTKLERFDEAQQILEHLMEVGIHQQNPILVASRELLVTVYLNLGKFEEAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8V2</accession>
    <name>A0A9P6E8V2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Guanine nucleotide-binding protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_946668</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8V2"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="200"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9524632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="40542" checksum="C42B3748433228AF" modified="2023-09-13" version="1">MGCVNSTGVDDEAKARNDEIETQLKRDRLRAKNEIKMLLLGAGESGKSTVLKQMKLIHHGGYNEQERESYKEIIYSNTIQSMRAILDAMPQLDLALAPQNDARRAIIFSMPAQIEADQMPRDVADAIRALWRDPAVQDAVRRAREFQLNDSAVYYFNSIDRMSAPVYLPTDQDILRSRVKTTGITETTFQVGELTYKLFDVGGQRSERKKWIHCFENVTALVFLVSLSEYDQMLYEDESVNRMQEALTLFDSICNSRWFVKTSIILFLNKIDLFAEKLPRSPLEDYFPDYTGGNNYDAACDYLLHRFVSLNQSAATKQIYAHYTCATDTQQIKFVLSAIQDILLQLHLRECGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8V5</accession>
    <name>A0A9P6E8V5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8V5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="211" mass="22956" checksum="2D17AB76472B5AF7" modified="2023-09-13" version="1">MLNSSTSAQHQQGAEVAVQKTFGKERGGSDESARNVKSISSFSIRSSASSAITTAYPSIGIAEDDLRNSVIAKSNLRAVVIVIFETKMNFLAMDAGIQATRRRSRNLSGRPVDVDFATGANDGGQSFARKMVTTGIEITVDIWPCRSESSPPEINYLRIATEEPSEQITSQSESIFGECESVTNSTHVSSKSEDQRNNLGDTDNFHETRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAN5</accession>
    <name>A0A9P6EAN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAN5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="365" mass="40093" checksum="1A1E59AE3EBB13DA" modified="2023-09-13" version="1" fragment="single">PTATATIVLAIQSNNTVRMNSEVEIVPDLDLTMDTTDEEKSPISSSSNPSQPMADLTLNTSAGTVGPRAESRRQVPVDRPDLFPSPQSVDLYTMPSRQTPMDLYDLPLRSQSPNLYDLPQRDGGHLYSLPSRSKPANLEDSSSGTHAPSQSQQAPTLPSASSSTSFVIEKRSNPALSVNPNYSSPLKLHSESLPQLYDLPPRTAPLPTAASVGMQLPGESVEFTTPVTQYPEFPQLNDVFSLQNPVKLQSGRTVMARRIPPITPPITGHERMDDFDGPPGGYALNTFTVPTANEIQATLTFLEDQNPGSSYRERAQLHRGARASQLAMEHQTRAALVEARESIRRARRDLRAGEFRLEQFTKRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBA3</accession>
    <name>A0A9P6EBA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBA3"/>
    <dbReference type="OrthoDB" id="3062477at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="527" mass="58148" checksum="60B82D2B00652438" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECC1</accession>
    <name>A0A9P6ECC1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_462872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECC1"/>
    <dbReference type="OrthoDB" id="2662290at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="41150" checksum="459CFBD01CE9ADEB" modified="2023-09-13" version="1">MLHGGRGFPLWFPSPSLNLSKEYRLKGFSIGDVGYFTPEGGFEFLFNILRAAKHPINGSASDVPEGFIPHSPLNARDIRKNWDFESGAYMCGPSVQASRVESAGLTFRSTSSEGAILTMPKGACKTELNSTSSFQRYVSQHAESWYKFAHGPCGRNVANGELRLVYGCDKSIAWGMAAFSNTTNAELKFSKSQHRSDGESSYSWEHSEIAEAARVGPGGHDNKDVGRLGNPARNQCLFLRSMTVTLATHIWEGLGLGIRAEPMFQESTLSLSDQSLWSMDPATILGTEYVFRLLSGVNAVLHAAEASGSSEVAVPVNKVRMQDGRKPFLNDVSLMVVSHPSSIINKLLFRLYPTATMAITTDAAWQAILPQVRSFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECP8</accession>
    <name>A0A9P6ECP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_857582</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECP8"/>
    <dbReference type="OrthoDB" id="6159137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="108"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="29206" checksum="53AE8BDD38510B6F" modified="2023-09-13" version="1">MASLLERMNISTEAGGPVRSRGNSSRGASAPYSRTSRPSKGDVEGQWSHDLFDNHNSLSARLNLASSAPKATIGNIAQRAIKDATALARSDTNAGGPLSIKGASSSGNVVEVTGLVTGTTPDDVAAIFKQCGVVTDQKAMSKKNEDPRIRITFKTPAAAAAAVKQFNNRPADGRILSVKVVGSSGASLAGRLGGADGLGLVREEGTVDVLMDSSDTGSKMRSDSLVKADPRAQVLVAPPGANPSDYTQSSWERGYGRRGGRGRGSRRGGPKRGGIASRMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECQ6</accession>
    <name>A0A9P6ECQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_770221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECQ6"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040402999" evidence="1">
        <location>
            <begin position="18"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="53740" checksum="AF986C28D898A867" modified="2023-09-13" version="1">MAFTFLYLSFVAALVSAANDWSQPCFNGECEYDLPSTPRGPSGTLKIWGPRHLISDITPAAGWAIIDCDPNLLKQNVRLVCEEGSADHCGRLSGGLETVGDASVGRIVRLPEECGGNAFGVVTNAWVPEDQTIPAHFVSRLTRRDGTLPTVQALSLGVNFSAVPAPADPNDHVRFAIQGANIEGAAGNMTRPPLPEVNGLQGRGFREWLDNIINGLKHLNEWNIDNQKQLSAIDVDQSFNVFDRSITCPPLKIGIRMDVNTKAHAVVSVGVVAMGTFLPPKIDDMALVSTFNANLDGELDLKASIGGEVSTGQISLYEVGIPGLNFPGILSVGPKFEVNAEATANLELAVDMKVGIHYQIDKASFTFPPKAGHTGSFNQGDTLLTLAAIPSTSVTGAISAHIIPRVVFGISALKDSVKADIFVDLDASASMTLKLVASAPQEIPVPLHARRSIESSPPELGGCFDIDVGFDVNAGAEGSFFNIFDASTSFDLYTKHWSPYKVCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECR5</accession>
    <name>A0A9P6ECR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Pyrolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_857732</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECR5"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 9 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040354834" evidence="11">
        <location>
            <begin position="38"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="12">
        <location>
            <begin position="178"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="400"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="14">
        <location>
            <begin position="627"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9526557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="878" mass="93203" checksum="52FC81E00CF53F74" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECS5</accession>
    <name>A0A9P6ECS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECS5"/>
    <dbReference type="OrthoDB" id="2870744at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="65631" checksum="C8E0A62635769B84" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED22</accession>
    <name>A0A9P6ED22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_837113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED22"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22045" checksum="5A5DC1535621A8C7" modified="2023-09-13" version="1">MSGQWIEGREAMVGTVEMAEDGTAYRVQQVAVCHKFLRDSTLPVPFHHHQEEPMCSTVSVSQASRTSSTTVHISTLRKPTATVGTRRREICSLHATASSNVWPLEKEDLNAEREGNAAGKKALVMQRINCIFGKYCVGGRVLIRGIVKACHEEKSVFPVNGVRKRGTRKSTRTNYLGIPRFGEVNFMGVYGCRSGEIHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED24</accession>
    <name>A0A9P6ED24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED24"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="57" mass="6327" checksum="C62DE0E599092BBE" modified="2023-09-13" version="1">MLSSSATDSRSVQGGIFPTIPPRPCQTLMYVCFVCSLLLPDTFKDFNHFQTPVLCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED98</accession>
    <name>A0A9P6ED98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA polymerase II transcription elongation factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_884676</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED98"/>
    <dbReference type="OrthoDB" id="125903at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032783">
        <property type="term" value="C:super elongation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003711">
        <property type="term" value="F:transcription elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027093">
        <property type="entry name" value="EAF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15970">
        <property type="entry name" value="ELL-ASSOCIATED FACTOR EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15970:SF2">
        <property type="entry name" value="ELL-ASSOCIATED FACTOR EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="9">
        <location>
            <begin position="15"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="164"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="337"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="531"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="545" mass="58189" checksum="6B7F82AFD4644320" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE06</accession>
    <name>A0A9P6EE06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE06"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="343" mass="38743" checksum="16FBE609CB05ABA0" modified="2023-09-13" version="1">MSAPSKSPYDIAAAYLNSTDFSKLPNPLALEAWTPLATSSYFRTFIYIFYGGFSVLVWDILQSIPKEYEFIKTSQNIVHLVTYVTARISPVVFLVLTMMNGGSYFRSLLASSVLIVWLIPPAATSLDPCALDLAISIFYSIAINSTCLLFFFRVRAVFPRNYWFTGFVSLIWLMSVASSILYTVERTTIPRVPPFITCLKQTKGQYGALMISMQASYELLVCASITGKLGYRAVVDSGVPLRHAGFWFMIRNQPFSLIRRRILQDNQIYFAVAFTFKFVEILMYTKLDSSMLAAVIEFLDVIVLSLLATKIVRDLKLGQGSPFTWDQRHSTIIRIPHGTSHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE56</accession>
    <name>A0A9P6EE56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE56"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="31751" checksum="6B7E57C808D42AF6" modified="2023-09-13" version="1">MRIAGFASTESKNQVPPTTPQQTPRVPVQHPQAEASVHFIPQAPRIRAGLPSSNFPVVPMAPMDPATAISSSVAIKQRPGGRRNSFVANDSWSSSSISKSRIKSRIPTTSTPTFTGSSTAGLSHAPHIPLASRYPAAKYHNVASPQVVNPGESWASSTPGVVPSPPPTPWTYTHSSASQAQHRHEPPLHPPEPMSWPTSSPDPSAATYHVPTFLQRLLLPGTLFPRNQTLKKSLNSLEICYLGRFTCIMLLETAIEGIVDIQDFETHVTMPPQYKKLKDTWEAFIDSVMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEA8</accession>
    <name>A0A9P6EEA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_426051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEA8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="338" mass="37990" checksum="DBA15A1FE19F0ED2" modified="2023-09-13" version="1">MNFVLKEQTAMLPSTRIEMWIQLPSGSSGQGFGKLFRAFGYDKFTALRIPEHMKRLTSPQVPSHFDANDTLDLVKQQIDKQLQEMEQLQVVRLQLQVQSDVRQNLQNDLSSKLDEIGIQKACYRSKQREILEKKEQDEEGLNRQKQEFKTIADRLKSLLKEHQDLIREIEAEKLKQETAYTASLRHEEQIKRLKERQAYFMVLTPKKVGKKSAERGRQRDTGADNEMAREMERRRQAATEVLQQARAEKVKMSASATVNALTDSVARVGLQDRGGPGPNAAQAMARRHYESLPTSPSSGAAALLPMEAPATIFESGPIAGSSGPRLSADVTSVKSAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEM5</accession>
    <name>A0A9P6EEM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_836417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEM5"/>
    <dbReference type="OrthoDB" id="5571888at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14810">
        <property type="entry name" value="bZIP_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="204"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="514"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="711" mass="75251" checksum="3E25079877FBEFB0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EER7</accession>
    <name>A0A9P6EER7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EER7"/>
    <dbReference type="OrthoDB" id="2626014at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="9020" checksum="5F491B007833C1AF" modified="2023-09-13" version="1">MIDNLKELGFSGNMFVTTREQALKTCEDILQLKMEDVKMQLITMYLSSQVARLRRFLDAERVWNDYPEPHFPLEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF53</accession>
    <name>A0A9P6EF53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heterotrimeric G-protein alpha subunit, GPA2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_894852</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF53"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF242">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="204"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="273"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="356" mass="40955" checksum="45BF2EEC66B72020" modified="2023-09-13" version="1">MGACISSPSGIEVSDKERELHRNAERELKEAKAKMAAQVKVLLLGSGDSGKSTVLKQMRLIHKMPFSTTEIEEFRQLVFDNLTRGLRYVLDAMQDMELSVEKEHIPYVELVDNARDLRDGESFPAEYHEALKSLWQDGNLQKTMERGNEAALPENLNYFFADLERLFNPHYTPTDQDIMRCRARTIGIKETTFHLRDHEMLMVDVGGQKSERRKWIHCFQDVTSILFLVSLSGYDQCLVEDKDANQMQDAMTIWDSICHSQWFKTTSIILFLNKNDLFEKKIPTSDIKSYFPDYEGEPSDPKAGRDYFKKRFARLAQKAGRSKEREIYIHITTATDTAMLRVVMAAVEGTNLTLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF74</accession>
    <name>A0A9P6EF74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF74"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040419936" evidence="2">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="14811" checksum="55C75A6DEAC73566" modified="2023-09-13" version="1">MKSLLFHALLTFVTVITSITAVPLPRPPIMPPPKGAATQQNSHRTATIQVVVGDQATRFVKNLNNKLKKEDFAIAKGEIPPRPASDKPFVPSKPINLPKPRPSMQTVNVQVPRFDGKKLGRKLSHLDAVPGDVISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFM8</accession>
    <name>A0A9P6EFM8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_732896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFM8"/>
    <dbReference type="OrthoDB" id="3063226at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="300" mass="35179" checksum="B8F81B3A5B15D28D" modified="2023-09-13" version="1" fragment="single">SSDIDKSRGRVYLLEGNLYYSPNSSRDILVPKTIPEGTNIFSPPRKNDGRLDYWSLDVASYLTPQWWTMQFGWLAFLDLSPTESAKEILRPTHIILHSHYSYPSLSPPLPRTFGYRSSHRTPRRLETALQKSWEWFSLWLALTSYSIACAQTHAEYFRSYPTLARIDWVNLLISQGSKFNIDLQWVDTLITSEPPNTVEMERFFELRKERNIRIIAKESPKDQQRRLSREKQPPTISARVFEWTPNALGEYECDEIDKRERADALGERDEDECRYDAVQNEWHICALWGRPKEGISDELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFN8</accession>
    <name>A0A9P6EFN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_732075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFN8"/>
    <dbReference type="OrthoDB" id="3265369at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="29038" checksum="99B624126108EA15" modified="2023-09-13" version="1" fragment="single">MSLRAFTVFQDAPASEPLQPRVLRSNVMATRASTRNIELPAPATEFAPLDKENYDPVTGERAGPSTLAGKKRKTGVLAAKVQPPTTETKLSKKDKDSQPEQKKRKASTSGPATSKSKSVKKDVKITGLSKKTTKRTGSRKMPSLPRLKEEEESGKTPVTQEEIDSRCKDLTVRPLADVSEAYDELAVFGTPSPVAEATQEKPKLRTVKAASVEPEIRDYFEPSIMSSTATNSTRLRAVSVDAPEPRAFSTPERKRIYAAFTFSSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFR5</accession>
    <name>A0A9P6EFR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_854847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFR5"/>
    <dbReference type="OrthoDB" id="2823912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="627" mass="72655" checksum="DCC5D8DD6C59B679" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFZ2</accession>
    <name>A0A9P6EFZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFZ2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="134" mass="14660" checksum="8D5A0B7A1F821B64" modified="2023-09-13" version="1">MLEEPNILLGICLLVGTCKICRGLNHLSQFGLLSGPLPLSSAISPTLQLSCYEPLLTSPERRRLAPIVLVKSWVRHWVAVNSFHSPLNAGRPFLADSRVSLGTDTCKCQEHAYFPPNSVGTVIRRKPSEPPAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGY3</accession>
    <name>A0A9P6EGY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_853683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGY3"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040537971" description="Hydrophobin" evidence="7">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="11351" checksum="609D8B5E94551B40" modified="2023-09-13" version="1">MFAKLSIIIASTLAVFVAAGGPLPVSNGIHNSCNTGPVQCCNTVKNSDTQTVNFIKEVFGVNAPITGMVGLQCSPISVIGAGSGANCGTQPVCCTGNHFEGGIAVGCNPINIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH59</accession>
    <name>A0A9P6EH59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_813374</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the VPS72/SWC2 subunit of the SWR1 chromatin remodeling complex. Also interacts with RBP1/DNA-directed RNA polymerase II largest subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH59"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 12" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="31"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="15">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9528823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="149" mass="15615" checksum="3C26379357F0B17A" modified="2023-09-13" version="1">MAPSAKAGGGGKSKAGAAAASAANAQTGAPRTIQTRSQKAGLQFPVGRIHRYLKQRTQHNVRIGAKAAVYTSAILEYLTAEVLELAGNASKDLRVKRITPRHLQLAIRGDEELDTLVRATIAGGGVLPFIHKSLTGNIKAAKKAEGQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHI5</accession>
    <name>A0A9P6EHI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_732839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHI5"/>
    <dbReference type="OrthoDB" id="3221808at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="132" mass="14648" checksum="0FED84E5FC983E61" modified="2023-09-13" version="1" fragment="single">LQDKWGVIVKHLIDKEKERCEVWKDEVQNLLVFSGLFSAVVTAFIIESYQSLQDNPSEILLSSIAANLQFMANTTAGVSATLSNNTHVPFSPTSPNKIVNILWFLSLVLSLASALIGLVALQWLREHLRPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJH7</accession>
    <name>A0A9P6EJH7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_833882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJH7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22887" checksum="2E303A9970285F43" modified="2023-09-13" version="1">MANTYLATKWKRPFKILFILTNVMLGVFERQRSGHTWCYGPGKKLCQFDWPAVQYGNLQALIFGEATLRRGRVDADEQLLKNDQLVLDGCANSIWVLFYTMHPSGRVGVLDPAHHKSRLSDKTKGNRTPAPGKLQGSEPIQVTSEQKLGLKYTGEDILGQPMQEEIGQYNNIAEPDAEESKDVVITSADNASLVLYLVKYISKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJP0</accession>
    <name>A0A9P6EJP0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 15">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_762357</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 15"/>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJP0"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031502">
        <property type="term" value="C:dolichyl-phosphate-mannose-protein mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23283">
        <property type="entry name" value="beta-trefoil_MIR_PMT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000034">
        <property type="entry name" value="Dolichyl-phosphate-mannose-protein mannosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="670"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="363"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="429"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="500"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9530966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="775" mass="88568" checksum="DA0A003C0C75AEBD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJX6</accession>
    <name>A0A9P6EJX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Required for respiratory growth protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_851236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for respiratory activity and maintenance and expression of the mitochondrial genome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJX6"/>
    <dbReference type="OrthoDB" id="5578174at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010487">
        <property type="entry name" value="NGRN/Rrg9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475:SF3">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06413">
        <property type="entry name" value="Neugrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="238" mass="27234" checksum="252BAF084BCA672E" modified="2023-09-13" version="1">MSKMMTLLSLGTLKSISSKGVRLPHRRYTQTAYQIAQQKWQLGGVPRPKSILEDDNTPVDLSEDNDAVNGVHPDSEPLHLRSPSLKPTPMEFKAHREAIRKAFPEGWSPPRKLSREAMDVLRSLHNTDPGTFTTPVLASKFRISPEAVRRILKSRWEPSSEKRSALIVKERKQQEEIRKKFKAEQHSKKKLQSMNVEELRRLSNGDDFWREKYSNPRTPQGEEAATLGVGIADQFTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKJ5</accession>
    <name>A0A9P6EKJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKJ5"/>
    <dbReference type="OrthoDB" id="2844016at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040249612" evidence="1">
        <location>
            <begin position="23"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="20900" checksum="3234F86CD9C19989" modified="2023-09-13" version="1">MLAFRVYSSVLIFSIISACSLAQEVLTSLPYNFTFSALNTTQPNANTTGVPLVLGQAGATGGYALHVSSTYSSYPYNDYDALGLQNKILLAYGTDGSYQTNAVAVQNGSPLIWVTTTLPNRPADPIFSGLKLSPTSEYPLLAANGVSSLWSLCTTKSPRPQTNILFNVSTPNSLDTTYDPASCYGVQILILPHSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM60</accession>
    <name>A0A9P6EM60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anticodon-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_868024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM60"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="110"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="42507" checksum="B75747311714FC2C" modified="2023-09-13" version="1">MSSRFEPSSIRNKIKREEVSQKNKKTKNQQKLQRRLAQAKLEASDPSLKRKRLSENVPRTLDNMREFDPSILTADPSSSNVAKEEELSHDLANDPFAEYFSTAADPTLPPKILITTGAKASKATYDFCDELVGVFPGAEFKSRKKGKGFEMGRIAGWAADRGYKHMCVVNEDMKKPNAITLIHLPDGPSAYFKLSSIELTKQIFGHARATPHFPETHLQGFVTRLGHAVGRMFQTTFPQLPEFQGRQLVTFHNQRDFIFFRRHRYAFRSTEKVALQEIGPRFTLKLRWLKKGLPAVYSYGEDAPPLVKEVPMEEEEKPAEPVPTANEEEDREENEEASPEPVLKKTVPPKQDEFIWQWKPDLETTRKTFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMI0</accession>
    <name>A0A9P6EMI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_849172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMI0"/>
    <dbReference type="OrthoDB" id="3065502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="283" mass="30803" checksum="0605967D391FBD64" modified="2023-09-13" version="1">MASSSKGQKRNSKSIDRPPELSLHLKEKLEDGDTTELPKNGELSLPATPAAQGSSLLSPYSANQSRPRLSLRRARSDLDAPLSPLPSPSSLYTFSRHSQLSTSSSLTSTPPYSPSGELFPPSIGGKEGSMILYRLASASGEEFEPLIPPSRPGDRSSGASSTSLASNNSLSGPLPATSRPLDAPRNSTRGLIPYRYDPLSDTESPMDEEDLLHDPETDVTSKHEKWEFPWRGVVNLSFLVFIVLALLALFALYPMFQFYRDKSKNDLIIGNIRINATGQNDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN44</accession>
    <name>A0A9P6EN44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_662791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN44"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="9532" checksum="3C107E08AD99B433" modified="2023-09-13" version="1">MNRMEADGCATELSLRVSTIMLLYLSTLIPMVGHTLFWSPDNRLFFFCYPRCFYFTFALLPVESMISESTSVHRRFPHKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENQ6</accession>
    <name>A0A9P6ENQ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_845868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENQ6"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="217" mass="24599" checksum="921C52A1396D2A25" modified="2023-09-13" version="1">MPVGIEAWITQIPPITRGWLALSVLMSLAVQSQLVTPLQLYFSFRSAFLNGQPWRMATTFFYFGSISLDFIFHLFFFMRYSRMLEESSFANKRADYFWLLLQSAILLLCVSPLFNLPFLSSSLAFVPIYMWSRRHPSTPISLFGIITISAPYLPAALVAFSWILNGTWEAAAGDLVGCAVGHIGWFIRDVWTREMVGGTTIFSEAPVRLKRLFGDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENT5</accession>
    <name>A0A9P6ENT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_624814</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENT5"/>
    <dbReference type="OrthoDB" id="1470711at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17932">
        <property type="entry name" value="DEXQc_UvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.486.10">
        <property type="entry name" value="PCRA, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF2">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE SRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="13">
        <location>
            <begin position="39"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="14">
        <location>
            <begin position="339"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="876"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="879"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="891"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="917"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="981"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1029"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9532506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1070" mass="118376" checksum="57FE98DD5065275F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPE8</accession>
    <name>A0A9P6EPE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_890751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPE8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="19552" checksum="27B90E64E35E069A" modified="2023-09-13" version="1">MSNIFYNYQIGFFLMNGNGLDEQLEKKLDAIADNDDYEIAAIFTDDENEGDANESDFEWTHLLIRTSITPFLDSLQYHTLNIRAVPRLHLLHFMLKLPQPASGLSRYPERPVWPSADPLSSLPSASSYLFNSQLDSTSFARSALIPIAVNVNVDIATAQSSCPSGAQVPYPNVPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQK4</accession>
    <name>A0A9P6EQK4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_756586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQK4"/>
    <dbReference type="OrthoDB" id="2832284at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="5">
        <location>
            <begin position="41"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="378" mass="42189" checksum="46AC6F440E2C7977" modified="2023-09-13" version="1">MKLISDRKSNSNTPLTTKPSPKLSPSLSPAAILAHSSIKRIDVHHHYFPSDLKKSKANSKIGWKTPEGNLPWSPSTSLAAMDAMSIDLSILSFPPIPSGSIGKIDRASARSRNEYAAQICRDHLFPVPRFGFFATLPFLDDVEGCLEEIRYTFDQLGAFGVSIASCYGEGKSAKYVGHETYLPIWAELNRRKAVVFLHGAQVPSSTPYPHEFLGIPVTESPNETLKAAAHLVVTQNRRIYPNVKIILAHLGGTTPFLACRVAVLSNHMGCALTPEEILEDFKTFYYETALSAYETNLLAIDSFVEHDHVLFGTDFPAVSRDMSNWYTNNLEMHYANDKIKLQRIMRDNAVKLFTETTNNPLSEEDTPEKEQKGDHDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQP1</accession>
    <name>A0A9P6EQP1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ran guanine nucleotide release factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_873476</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MOG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQP1"/>
    <dbReference type="OrthoDB" id="10255285at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF0">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04603">
        <property type="entry name" value="Mog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19686" checksum="BCC6091E4A7B0A41" modified="2023-09-13" version="1">MIQRGLFGGAITAQTLEDLVDASDLRQVPDTQEVFMYPQSGESIIIEILQKVELSDPEDAIKFHFDSLAHDNSAQSFQVDSVVVSSAHTREDRTPTPICLKGLQMVPKFNQVTPDKVLIFMALFRVETKDIDLVVTFNVPIESIDGGATDAAGELRAEQDFNTFVQSLRILDFHLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER29</accession>
    <name>A0A9P6ER29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_755760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER29"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="8">
        <location>
            <begin position="130"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="400" mass="46069" checksum="2742875B718EDDAA" modified="2023-09-13" version="1">MVSIGWTIFEKLYIYKGVFYVVSDTPATVPELQFIISKGIYIKPANVGEEERLPSDHEMKVISTKQAKKLFGGSSAQVMDGHSLLVNDPPQFITHYYHWSAELWFGFWRTYSSLDPNISELGNTTLPPLRRMVFNHLDNYHWRDYANMNQWVLRSSFPSISIEFIDEWRDRAEMGRPFVFERVVLVDRAASMFGYNYQRYQRSAGPAFALPGSMKWWQPIRNNVVEFAGVAPEVGSGTTSKPVITYISRQQWGRRMLIPEHHDKLVSELYKLQDEYGYEINIVNAESMSRLEQIALAARTTIMMGVHGNGLTSLLWMNPNPRSTVMEFFFPEGFAHDYEYTTRALGMTHYGFWNNEFFTSPGLPLPRYVEGFQGNAIPIDGEVVARLCVERLSLNSEVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERI1</accession>
    <name>A0A9P6ERI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERI1"/>
    <dbReference type="OrthoDB" id="3260940at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="835"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="913"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="961"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="739"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1221" mass="132086" checksum="1B61DC29DADF3CE4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERM6</accession>
    <name>A0A9P6ERM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_830979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERM6"/>
    <dbReference type="OrthoDB" id="5556956at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="26112" checksum="8A4FE1C4F48B5740" modified="2023-09-13" version="1">MKMVTKAATNMTLAGNVVVFSDISMKAGTTDSVSKAQMKAFMSSKISKLSTNTENPPKSNRTPKEEEEERTNLQNDALLHKLVHTKLLSGSMNTELDLTPAKKRKAFAGRILELTGDVKLGKGEKEIRVAERNKASKRVREGIAGKQKERSKQELEEAKNLGNYHQSLKKVFEASSSISSNRNRQKGLGMGVGKFSNGLLRLSQADVNKAAMETSDSFRGRRGFGRGRGRGGFKKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERR1</accession>
    <name>A0A9P6ERR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_831835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERR1"/>
    <dbReference type="OrthoDB" id="2929049at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61569" checksum="6F7CC2AD13DF1FFF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERT8</accession>
    <name>A0A9P6ERT8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERT8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="11923" checksum="3E8E1A80E31C4F4E" modified="2023-09-13" version="1">MERKLQSGSTTVNFTKEFHQPTARILEELKQRFSEIPFPVPPSQSQSPNSMSLFNNSHQVSMSNVNIQMNQSYLDAKPLQEQLNLVLRTQRVQTSVLFAYSGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERY2</accession>
    <name>A0A9P6ERY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_756796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERY2"/>
    <dbReference type="OrthoDB" id="3229610at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="332" mass="37584" checksum="7DF87989AE126080" modified="2023-09-13" version="1">MPLNDANSTIPPSHIGLIVGYIVVFLSTIYRLCHRWNRHQLWWDDFWASVAFFCAILLCCLLVMGDTNPHTNIRYSSFLAWIIFPLNSTTIWSSRLSIGTTVVRILPRSRYRTISIVVNWLFCVMWLATVIQKIFVCGIPPPAVPKHCKFARTTAILGFTLNFLGSMWLVGWPAFIFVSPKNKRMHVEKIKLLPAHHRLLVACFSTSMVLLVADVYHGFYFFYPGSGRMGGITGHLECMISLFICNVLVLVAAVYRLLNKPKPHTPRRRRLHPNQKPISIPGGDVEKDRSSIKFACQDTDCAILGPKINKDEQQIDTSQVEGVSLSIKQAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES42</accession>
    <name>A0A9P6ES42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase catalytic core-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_843455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES42"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF3">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040409396" evidence="2">
        <location>
            <begin position="29"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="3">
        <location>
            <begin position="120"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="36271" checksum="9CD44EC685FD8E1C" modified="2023-09-13" version="1">MASKLINLIALSTLAILASSFGSTNVNALSVSSNHHARSVAHQAFAAKKRAAASGRPKCKPRPSSSAAAPGSTGAPAQPAAQPAQPAPAPPAQGNPTPPPASSGGKGLLAWGAGSRPDLLKNLKVGSVSAIYNWNPEPFPEAEAAGYEYIPNLWGERDVDFVRNNIKPGQYAHILGFNEPDHGEQGNMDPGRAAQLYKEIMVPLHNGGTRVSSPAVSNGPNGLEWFKQFVQACGSLEACGVDFISAHCYATDTAYVQKTFQDWHDTYGLNVWVTESAAMDFVTYQKTDVTKFASEMAAWANSQPWIEKYSAFMVADNLGNVDPSNAIISGSNFNALGNIYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET22</accession>
    <name>A0A9P6ET22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_844074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET22"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040415939" evidence="5">
        <location>
            <begin position="20"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="524"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="762"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="603"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="832"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="863"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="879"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="921" mass="98859" checksum="B85EF297EC96C7D0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETI5</accession>
    <name>A0A9P6ETI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_231973</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETI5"/>
    <dbReference type="OrthoDB" id="3361414at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="213"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="310"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="523"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="701"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="702"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="763"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9535125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="838" mass="90556" checksum="1BC2694317D9C274" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETJ3</accession>
    <name>A0A9P6ETJ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_830821</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETJ3"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="84"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="32680" checksum="E69AA108513DC329" modified="2023-09-13" version="1">MAPIKTPWTRLIRFVAVETGRVHIGQPVDSDLDVGLAYAQKSTIKAYEILGSTLSPGDAHVSSEVLTIHTLLSPLDSSEIPIIRALGLNYSDHAAEAKMAIPDFPILFYKPLKSLLGPGAAIIIPRAAQPPKEHLPDYEVELVIVVGKAAKDVKEEEALDYVLGYTGANDISFRKHQLAVSQWGFSKSFDNTNPLGPVLVSNSLIPNPQTVPLKCTLNGSTVQDGTTADMIFGVRHTIAFLSQGTTLEPGTIILTGTPKGVGFVKQPPLYLKDGDKVAVWVGGGIGTLVNEIKEEGKGKLTRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU35</accession>
    <name>A0A9P6EU35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_227326</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU35"/>
    <dbReference type="OrthoDB" id="406287at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="402"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9535064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="459" mass="52259" checksum="8683E785098A2E9B" modified="2023-09-13" version="1">MARPPSPPLGKGYFSAPFERFVRDDTFDQLSSAFTLLDTVETYFDSHVDLLQRKLQKHSDKLKLAAEEASSKIKDLKIKDLSGDLLTENFERELKGLKTKVSSRMASLSASWQSSKVVRTREKVSFFFGVMNLLFSALIFGIAPQWVHIAYTVQGLYLLPLRFYQYKKRAWHYFLFDLCYYVTILNFVFFWLFPSSPSLFVACYCLSHGSLASAVITWRNSLVFHDQDKVTSLFIHMYAPFSFTVIRHFYPNAQDRFPALLEVPHLNPWKALALSGGIYLIWQLLYWKFLMVDRAAKIKSGQRTTSFSYLLNDKRSGIGRALSKVPEAYRVASFMGGQFLYAIITELPAVFLLYKSSTWSAIFLLIIFSVSVWNGGGFYIEVFGRKFERELEALRKELAEASSRSNSDVGTPNNLSRNGSHSDLSSLLRLTSAEDLSRSESSASDSSAPNSPHESKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU39</accession>
    <name>A0A9P6EU39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ferredoxin reductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_755432</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU39"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="35"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="35874" checksum="BCCBA9DDE3E86A3E" modified="2023-09-13" version="1">MSRFLLVFGLGFSVYFFMDDPRQPVYKQEDLVLSPKKFTRTILTSTKDTGPNSKILELKVPPALLPNKDAFSSIWSVYIKDDDIQVERPYTPLNGIDEEGRMQFWIKKYPQGEVGRWLHSKKEGERIEVRAPLMTWAWKEDEWDEVVMISGGTGITPFIQLFNTEICKIRPSSSTRFTLLHGSRTPGELPPSELTEPMALYAQKHPEKFRLDLFVDEDDGSKPSASLPPLNIGRISDSALEKCLGSEKTKSSRWPRLFSKQPTKEDVSTKRILFLVCGPEPMIRAVAGPYGRNYSQGPIGGVLKTLGYTSNQVYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU89</accession>
    <name>A0A9P6EU89_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU89"/>
    <dbReference type="OrthoDB" id="3269398at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="17723" checksum="BE4186162B3AB8B2" modified="2023-09-13" version="1">MALAEQGTGSGPSKLYWQFEYLVDNRRMDLSQPRRTLEGEKTLTPLMFSCSPNLLLPRQGKRINLIHIFKKSVAQKLVAEKLQPPGSYQNLHRRTRSQGVHDDNVPPRAVSDHIRLGRSEVSATSGSLGQHRRVSSADQHQPSRTSSQYHSGRTSPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUB1</accession>
    <name>A0A9P6EUB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUB1"/>
    <dbReference type="OrthoDB" id="3353448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018824">
        <property type="entry name" value="Conidiation-specific_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10346">
        <property type="entry name" value="Con-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12397" checksum="0BE18DE3152D09BB" modified="2023-09-13" version="1">MPLFGRRRAAPRTMHHTTPLTTSHRTKRGGLFHRKDRDRVAGGYKAALANPNTTHAGRRHAKHELHSMGRSSHIPLMTRIKRTLGIRSTPRAHRTTATHTTHTRRTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUY1</accession>
    <name>A0A9P6EUY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_6404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUY1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="24682" checksum="75BD7EA7506B6094" modified="2023-09-13" version="1">MCQRRRWPLELYALTINALAIRKPSNSFNQSSLSARQHLLYSSALKLASKMPASRTSLESHLSRNTAITRRTDSPSVTQLKDRMKLGDGLQARGRTVYNYSQQAPLSQPTGDQCRQDSRIQHSEDSFQPDCTLHDKHDVRIEILEQLGFESARSLEEYLISIPNSVTPSAVFLSLTQSSKKLDGGSRSPSMGRLSDEEALKVADELFHMYIDKTVFYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV94</accession>
    <name>A0A9P6EV94_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_888266</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV94"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="21357" checksum="07D9947FB22173CE" modified="2023-09-13" version="1">MDGMDHGSSGTDSSSMMVPYLHFAGGDNLLFKAWAPKSSGTIAGACIGLAVLAILERWVHALRSIFTVHWHTRALAMCAERDRALMEHLHASTESERDSALASDEDAIESVDRYPSIQPTTSPVTQRYPHLRRTVAPFIAAFDVPRGLLYIFQMILAYTLMLAVMTFQAAYIIAIIVGLGLGEILFGRAGHLSGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVD3</accession>
    <name>A0A9P6EVD3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_842093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVD3"/>
    <dbReference type="OrthoDB" id="1290869at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="263"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="673" mass="74984" checksum="BB6D450D4A4EE7F9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVI5</accession>
    <name>A0A9P6EVI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_865915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVI5"/>
    <dbReference type="OrthoDB" id="88at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9535752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="15933" checksum="B7F8FD256FBB8FC9" modified="2023-09-13" version="1">MRPLLRAQLRSRPANGHVAYLPQIRKLVFEFCDKWPSSANTRTYILNHIQDVAKENPHVEVVVKQRNQKEPIVRGFYVNNRDKVIPLNSLEVNGIQKKVQLLLDSSGAKIVPLKRRAVESMTESTRGIWSGMHADRPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIC4</accession>
    <name>A0A9P6JIC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157974">
        <property type="protein sequence ID" value="KAF9521914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIC4"/>
    <dbReference type="OrthoDB" id="3053868at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="927" mass="105937" checksum="4DF8C73AB23EF7B9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ61</accession>
    <name>A0A9P6JJ61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157935">
        <property type="protein sequence ID" value="KAF9522753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ61"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="174" mass="19374" checksum="6D9E3EF58F1F2044" modified="2023-09-13" version="1">MTYYPEDNTMFRRLVTTTTKRIVNPDDPLGEVRYLTKTYITETCVSISDEPPAISETTTQAQQPMSPPATPPPVTPSPPATPKKAASQHCQVPLSRFCQNYNSYKKREAVQKQELRLKGARLLRAGQRVHEDQCLAALLGVQREYIVVSDSDNDETAVSEGGDEFIVLSNDSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJZ3</accession>
    <name>A0A9P6JJZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_910729</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJZ3"/>
    <dbReference type="OrthoDB" id="10261807at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="16"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29475" checksum="161B98BE3E35C3B4" modified="2023-09-13" version="1">MSAIKLVPRWSQDRGNADHGWLKTFHTFSFATYQERDHQQFGSLRVINEDRVAPRTGFGTHSHKEFEIFSYVVSGELEHQDSMGNIEILKRGDLQLTSAGTGISHSEKAHGDKTVHFLQIWSLPSTSRLTPKYFTRHFSDEEKKDQWVRIVAPVDAERVSADREGSGPVPVQSPLTLFATLLGPGKTLERALEGKKGYIHVIQTTGYNSAKAEGASVKVKGKGSHENLQLREGDGGYIFVGKQGDELVVENNGDRVAEVLVFDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK87</accession>
    <name>A0A9P6JK87_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK87"/>
    <dbReference type="OrthoDB" id="3056337at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="67006" checksum="76A2968353625A92" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKG8</accession>
    <name>A0A9P6JKG8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_898094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKG8"/>
    <dbReference type="OrthoDB" id="3269685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18785">
        <property type="entry name" value="SF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="40209" checksum="B74E7918AF35CB14" modified="2023-09-13" version="1">MQIILATDALVVGIDFPNVEDVIDLDCTHPNHGKQRKGRAGRGENVKDPRGITYVTKATMEKAKKMLEKPRSDICDGGGKWVEQGLHYGMAQLLLASCYPDCEDDLYENPKADPFCFCGSKMCEEERQQGGHRGPCRCSGCIPEPALLPLRRATAQHETLPKGLRLTEKMITKGTKRLLDFRKELWNDISLDIGFASPGAILPETHIKLLLDNFARIKSLDNLSTYISGLDLLNGHEERLFTLIQELRTAFKIPVYEPPPSFQAPSLSQPDTTSLTPQVAGTSQEKVPAGPSYEDFWANFQRPLAGLSSQVFPSSIDSNISDPFNTQTTYPNTQLATPTPMPFLSQNQNTQPRSLIAGKTKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLI4</accession>
    <name>A0A9P6JLI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLI4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="32399" checksum="43B41D98F5155AE0" modified="2023-09-13" version="1" fragment="single">MASKKRTTYTSKDTLPLAETHSNPEAILRRTTSGTTSKVSSPIATSSALLECVDAPHIVAEATDKSLRDTSYNRGKWRPCNFKPDEPCPNRINKKLTDAEIKTIPGTYHLPNTANYHKILAQGKSKDTQKSQPQTPKVDPIVIPPIKPEILDARHSDDCLQEERPCPHVYDITNGNDIFYNWLERKFQDCRLQPCPRRYTPLPSKHILSILDIDYEVTTKENRQKAWEINRETPYQSPVTSKPASRQPSRRPSPSRNIVAASTSTPTTQTFHHGSNNPSGSGDPSPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLK2</accession>
    <name>A0A9P6JLK2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_860499</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLK2"/>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="578"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="589"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="625" mass="70757" checksum="DDF3AF5E8A86E902" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLK3</accession>
    <name>A0A9P6JLK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clp1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_796601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLK3"/>
    <dbReference type="OrthoDB" id="2570975at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39195" checksum="5701A637A3963931" modified="2023-09-13" version="1">MPPRQSSSRSLVHRLRGSLEAARRHTRLNSRASASGSSPNVSVHLKKSATTATSRTRSSKGSSKPLDFTVTILPAPISDVEMGDATASTSAPRKTQVQMPRELPRPAFEEIDYERLTEIDDSLKDVPITFLRQHLHVMGQDFLQSLGSTTIPQSKTLSKEIDIMINDMTSIAPSHVLAVTGPKRPGAKSTKVSLYAVHSVVFAAQCSRMPKFPPMLPLPPHQAGSQTVRVPVFPISVPHATSFPQLLKFLYCKRPTSLIREMIPLAPPPGLFEDQDPSQVIHYATELAKTFTDAKLVQVAGEVHGLWRNLCGFCVDDELLWNTLDLMWRICLTALAISTGKPEVMISPPSTQSSSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLU8</accession>
    <name>A0A9P6JLU8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_818486</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLU8"/>
    <dbReference type="OrthoDB" id="440202at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="8">
        <location>
            <begin position="195"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="7">
        <location>
            <begin position="394"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="54744" checksum="A9C9F00C3668DD36" modified="2023-09-13" version="1">MPLNYSKWDQLELSDDSDIEGHPNVDKKSLIRWKQRDIHEKRDERKHKIASLHAQIACNKVLLPRIEEIAKQLASTSGSTPAPVYFNSLVDKLQNNPSKDCPPGNNPDKIEQTYDGMLLSLLKMVSEKAKERIKDAAVLESEKEERLAKELGVEMALHVKMLGETIEKDAKQIEIEEAEQKKKITMDDIHEGFDSKYVPPKPEPAPVPTTTGDKKGKGKEKQKVTTVEVLNPQAAGSSTGDPEDNEDEDDGDDEGIPEMTPSLTEFSKISIGDYQKSFEFIQSHRDVYVSGASDALFIAAFKAEGEGKRKYAKQCINQSLLLQYCEKLGKDGVGIFFKRMSTGNRAAMKIFEDDVERTYKHLVERVRLNKEEAAAEAREQIQLVAENPNTVISFNVPDGPPPENLVLEGPGTEGMDIEEVRKALEFRWNIFSAFPENLQTALRGGKLEDVNEVLGSMDVPEAEAVVNSLDAAGILSFAENKFRDESGQPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM34</accession>
    <name>A0A9P6JM34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_885296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM34"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="449" mass="50527" checksum="0DB90497AD97AAD0" modified="2023-09-13" version="1">MATILRPELLDQIFGFLEFDLVSLKNCALASLSLYHEAERHLYKHIELLPTTRRGKGIAFCVTQSQLLQLLVAKPHMTNCIQSIYMEITPEDLFIPIQSDDDYADVKTSPTPPLPSLCSLTICSFKPEHCPDWSEVKRDWTCVEKSFRIFWEGLMYLPSIEEVTIRDVYGFPLAILDYCQNLKRLNLFNLLLSTTSLPLRAPPSQEHLSPLLQVRYLSLSDNEDGLSVLLEWLTESTALTATKCSLLRTLEFQPQSLGCFNSILEFMNTCRLGLMSSFRTSYTPFDSPSGEWSNFYPSPPLEMEFPSLPNLHKLSIFADILYDTTQGPNGVHRRYVSSLPAIGEILRRFHNTAVANALKTIDIHLTVLTDAWDSPVLADIDFAPLASVLSQNSASLTVVLVLHPLENKPGTPYHTILMATLISEVASHKDLRGLLTAGHVLIKSSEHYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMW9</accession>
    <name>A0A9P6JMW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_857740</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMW9"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="506" mass="57600" checksum="DC7D746D184BFD4A" modified="2023-09-13" version="1">MDRLLLSDRFHGAALAVFVVLLVRVLSSWFNKQKYPPGPRPWPIIGNAFDIPKEEAWVTYANWKHKYGDIVYMNVVGTPMVILNSYQDCVNLFEKRSEIYSDRHQLIVASTLMGWDNAITLCPYGDKWRKYRKICAQSMKREVVKQFQPVQEKGAVHYLKMLLDDPSNFKSNFRFAATRSIMWNMYGVEITDPKDIIVGTTEEAVKYALQAAMPGNFLVDFFPPLLHLPEWLPGMAFKKWARKGRKLTQDMLDLPYNVTVKDLEEGNPNTSFTAIALEKGKDVDIIKWCSGTVFSAAVDTSVATMQIFFLAMTLHQECQKRAQQEIDAVCGNGRLPSLEDRERLPYVEALMKEVLRWQPVVPMALPHRLMQDDVYNDLFLPAGSIVLGNSWAISRDPDLFENADSFIPERYLPQDGKVLPLDPLKFAFGYGRRICAGIHYAENMMFITMSRILAAFNIKPPLDESGNDILPEAKFESLLVREVVPFACSIKPRSQAAQALIHTSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN63</accession>
    <name>A0A9P6JN63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_836827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN63"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="301" mass="33734" checksum="943AD077CE9133B6" modified="2023-09-13" version="1">MAALPSTQHLLLDFDQDTLRWPPLIRHPRLYDVDDAESLAALPPFCNPQVEEHEEFPPLPPLRRNSKVQDDNDFPYLPALRHNPRVTDESVDVSEENEGSLLPPLTRKPRVDNNKLPAPPPLAQNPNSKISVPHGTFSTSTSRVYTPLNIPSVEGSLSLTLTIPAQPNFGKKPFVKISRKRMRFLTPLGVFSPPTASTARSAKAPTAIPPNSRPPPASDYFSYSAPHRRTVVAQPKEWASFPHPVEHIRHTLDMDFFGEPPQDQPPLHFNPSQVRLQNIHEDVLLSVKKDADYPNILDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNC5</accession>
    <name>A0A9P6JNC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_463302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNC5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="12716" checksum="6A91CC3D0A2C2B3F" modified="2023-09-13" version="1">MFLSSGFKLSLSFFLYVIRYSISIFQSLSSLIRNLTTHSLSLSHYPLICLSLFIPLRSIASHRYPILFSLNSYAAYIYLYHRTIPHKGSNPNLNHFQILVSRFTYTLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNK9</accession>
    <name>A0A9P6JNK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_449857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNK9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040462766" evidence="2">
        <location>
            <begin position="20"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22908" checksum="4FF5C9C741D0B6A6" modified="2023-09-13" version="1">MVVLTSLIIISGFATSALAAPFHKLEARSQGIDLETREPKIDVVRIGHLVNKVANAAQNTANIAATVGSVIPQRQTAQYYQRDLVDDSELDVREPSILSAALHVSHAVDSLTHHNHRRDLEVDEVDARGMEDSESMNIRNMYDEVDALEGREIDEDETFDARGFDEEDLDAREVDEMEEESRHEDDDEEDMLARGLDTEYEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNT8</accession>
    <name>A0A9P6JNT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="9">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_855564</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="9"/>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNT8"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(P)+]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000940">
        <property type="entry name" value="PRK00094.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000942">
        <property type="entry name" value="PRK00094.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF1">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="10">
        <location>
            <begin position="47"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="11">
        <location>
            <begin position="230"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="52"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="305"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="412" mass="44813" checksum="539747BAE5FCA8F0" modified="2023-09-13" version="1">MSRVLTSLLSTLSFGRPRRSFSLPKRLVPSTFPTMVRSKAQPEQNSKVLVFGAGNFGSCLASHLGDVEHNVYMWAREEKLVKHFNKHKRNPNYLTDHEFPSTITAVGPDMPDKEFIDGMDVLLFAIPTQFLRKTLKFLRPSLDTDNLPLLIFVNKGIEVGTNALTLEIIADTCGPDIAKAATFISGPSFAKEIVLRQPTSVSVASFTEEEAVKTTNLFHQPHFRCYTGGDPIGLELSGALKNVYAIASGMSDGLGYQNNARAMIITRGLSEMTVIGTAYGASPLTFLGLAGVGDLFLTCSSSNSRNYTVGHRLGQGEKLDDILRTLGSVAEGVETTKGVRKIIDELGVKAPIANAVYEVLFNGKDTRDAVKELSELPPSKELELPPTTGAPARRLLMKLGQTEQLNGQTLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP65</accession>
    <name>A0A9P6JP65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gti1/Pac2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_815730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP65"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="33630" checksum="A2C98D6732D6E350" modified="2023-09-13" version="1">MQRATLTGIRIRSPSDARVIFHSVYLNILPMVTRRLDTEERSLISSGSVYVWEERGQHTELTGVGIERWTDGIRWGPSRVREGFLFYHEKPATQHLSHADGSFDPMRSVLIKQTYTVFVDTPRGQRKWHLIAYFTEETVHRLRSIDDIVQLNSVTVPSGLYKSARSAKGRPDHIFGQDSEGSAFAHLEYVPYAPPGTTQSPSPGPSTAAELPHNSLSSWTTPPQDHRRSPTSRPSSSLSNSSAPDPKILVPLSYLEEHPPPRRHPTDEKLLMMLTTRCFRERQNWLHGSSAPKHRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP95</accession>
    <name>A0A9P6JP95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_352927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP95"/>
    <dbReference type="OrthoDB" id="3256408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="767" mass="83038" checksum="215D2E904A244F68" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPC9</accession>
    <name>A0A9P6JPC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_855236</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPC9"/>
    <dbReference type="OrthoDB" id="16510at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="11718" checksum="7EB0EFC021EB4E09" modified="2023-09-13" version="1">MSTEDRAAQLIFGPNVLANSAINSTKFLSACFAGAAAGILGLENWAGFFLFLIATLLSAGIIYSVNCKGRPNRYFQGGFIELVNPGQDNAFTFVLMWTLLYGIVHVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPZ9</accession>
    <name>A0A9P6JPZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPZ9"/>
    <dbReference type="OrthoDB" id="2553859at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="12688" checksum="0D5808A75A6C7F10" modified="2023-09-13" version="1">MSSTKAIKLTYVLNPPTSVESDKSLESLLPKAKSHEYPVVLSAKSDQATSEKDTRSYYTDLRKAIERARVEVGEELTEWRDIVGKEELGKEGKKGEVVVEVDEDEGEQEEEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQC1</accession>
    <name>A0A9P6JQC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome c-type biogenesis protein H TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_790062</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CYC8/SSN6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQC1"/>
    <dbReference type="OrthoDB" id="418911at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000403">
        <property type="entry name" value="General transcriptional repressor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000078">
        <property type="entry name" value="Transcriptional corepressor Cyc8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056413">
        <property type="entry name" value="TPR_CcmH_CycH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23914">
        <property type="entry name" value="TPR_CcmH_CycH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Cytochrome c-type biogenesis protein H TPR" evidence="11">
        <location>
            <begin position="90"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="198"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="237"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="380"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="466"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="532"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="674"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="768"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="870"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="899"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="959"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1012"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1063"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1088"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1118"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1130"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1153"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1172" mass="128866" checksum="AE1B11A547FFBDF9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQD4</accession>
    <name>A0A9P6JQD4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_852261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQD4"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="14803" checksum="3AFA41A1673889C8" modified="2023-09-13" version="1">MGRLRRSRAHHARRDVHRASRTRVRGRDLDQIQMIDLDPKNRAALETQALDYEKPGLGQHYCVECAKYYETDVALQSHWRSKVHKRRCKQLREPAYTIEESERAAGLGREVKPPPVAALMETGDSVAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRV3</accession>
    <name>A0A9P6JRV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain-fatty-acid-CoA-ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_851795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRV3"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="104"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="690" mass="75077" checksum="1959E996666B46D7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSA0</accession>
    <name>A0A9P6JSA0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_810612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSA0"/>
    <dbReference type="OrthoDB" id="3204157at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="202" mass="23328" checksum="7847773F3FEB1551" modified="2023-09-13" version="1">MHRSNDFWFSDGNIVLQTEDTQFRVHGGVLTRHSQVFKDVLDIPQPGRPSEPQVDGCPVVPLFDDTEDVQAILSILYNNINAYNVQGPVAASMIVGMLRLGKKYGIHYMWKEGLRRLKADYPTKVEDWQPERRMIFGDPKVYQEKLINIAHELQLETVLPALYLACVSGYTFVRIIFSKLIVRGLTNFHQGWPRRRSSRNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSI3</accession>
    <name>A0A9P6JSI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSI3"/>
    <dbReference type="OrthoDB" id="58416at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="37"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="238" mass="27285" checksum="46E25DCD2339A901" modified="2023-09-13" version="1">MTSDPKTRYPLICLPAGAADWDWTNSAATWAIQMTLIHNVFIRHLNSISYHAPLVKTGDEQAFVGYCLAFTEHLHDHHDGEETIIFPFLQEKFDMSVNIEQHAKFNTFLAAFEGYIKNVQSRQDNYDGNKTRGLVEALGDVLVEHLHDEIPTLSPERLATYDKKDLDAVIAKEMTHIKAGSLTTFVAIATHHDYSTAPTWPPQPKPVGWILRNVIYWRHPSYWKFSPFDRNSQPQTYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSS8</accession>
    <name>A0A9P6JSS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_809414</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSS8"/>
    <dbReference type="OrthoDB" id="2154091at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="675"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="795"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="717"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="749"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="769"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="795"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="841"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="990" mass="110265" checksum="7874E3C2AA396EC5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTH2</accession>
    <name>A0A9P6JTH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nuclear condensing complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_759730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTH2"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="587"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="542"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="965" mass="108616" checksum="95318182584FA8E7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU10</accession>
    <name>A0A9P6JU10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nicotinamide-nucleotide adenylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU10"/>
    <dbReference type="OrthoDB" id="5591297at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285:SF0">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37009" checksum="6C203B7F33190F77" modified="2023-09-13" version="1">MTETMTTQEHIRGALLAVRRAAPEILARLQRGLSQPPLELIYTSHPRWPLPPLPSNNATRDLRVSILDSSFNPPTKAHLALACYSRPAEWASSEDQKISEEYDANLLLLSVKNVDKSLKAGDATYVQRLEMMTLLAHRIPSVTFDGPIPEEAEPKPVTSNVAIAVTDQPTFVGKSSVLSQFLTERLSTLGEGPETSRPELTFLLGLDTLERLFSLRYYPSDSAMACSLRKFLSPYPGDNCRIVSANRVFISSIPSPEDWAIESRSLREDLEKSGRIATINLDQQLSTYSSSAVRESLAKGDLSSSGNESLIWKDLVTSEVARYIQEHRLYTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV28</accession>
    <name>A0A9P6JV28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_805537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV28"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF236">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="128"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="27017" checksum="7035E49934B27A58" modified="2023-09-13" version="1">MVKKESKKKLTSTAITGAVASPVQVVFPEISTKQELQYRTILEDQILIIDDFLDPGECKAFVKFIDSLPLELTPPKKRGEAERVKQRFSVSSIGFAKVLHERLLGHLPSFPYPSHMKRPPVAAENPRKPHSCNSNIRVYKYAAGQYFGPHYDDSVRDNLTGANSEWTLLIYLTGVEDGVDGGETVFYKEDRGKPRETVTPALNRGTALLHRRHGAECMLHEGSPVKSGTKYVLRSDLMFLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV41</accession>
    <name>A0A9P6JV41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV41"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="38372" checksum="53E61BCB7E6B8AE5" modified="2023-09-13" version="1">MSAKNTAIVEGTVNPYTPFAFLSPDDAFVVSFIQYVVVTSLGIMFWDILNYVPSDYEVIFQTKFTWKIIVFLVARVSPVGFLLSMSLAVTSDRVSCRALHNSWCALFLIAKTSTSLLFYFRVSALYHGNRFVSIFFAITLVTLTGAACLLFKGMTSFHIGPTSYCGITIIPQYVLWVTVAEVFNDILTSMAIIHKLGGNTWQERKRTWIRAFRPSRGRMMQVFMQDSLIYYLIAISLNVFKIACFFALSSKTDSSIRILAGVPNTVVINSIALRVFRNMKLGLPGLVPIDKCAGAVSDIFFQPRLVSGGEWACTDLESATKASSTKREEIGQSETLSEVKIQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVK6</accession>
    <name>A0A9P6JVK6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trafficking protein particle complex subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_866984</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVK6"/>
    <dbReference type="OrthoDB" id="10256906at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055505">
        <property type="entry name" value="DUF7077"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022233">
        <property type="entry name" value="TRAPPC10/Trs130_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056913">
        <property type="entry name" value="TRAPPC10/Trs130_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23274">
        <property type="entry name" value="DUF7077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12584">
        <property type="entry name" value="TRAPPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23036">
        <property type="entry name" value="TRAPPC10_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7077" evidence="6">
        <location>
            <begin position="712"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="TRAPPC10/Trs130 C-terminal" evidence="4">
        <location>
            <begin position="1026"/>
            <end position="1173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1188" mass="132924" checksum="939E87197D08980E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWJ2</accession>
    <name>A0A9P6JWJ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWJ2"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="336"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="791"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="973"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="748"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="817"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="881"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="973"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1144" mass="121898" checksum="7F803F724564AD07" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWQ6</accession>
    <name>A0A9P6JWQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_843128</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWQ6"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040426335" evidence="11">
        <location>
            <begin position="28"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="58407" checksum="591D37EA975E3BBC" modified="2023-09-13" version="1">MSLLSSVLSVTLLATLCLIFKWRKAHSVVTQRRLYPPGPTTRSWIFGNAGDISVETQCDRYTEWYRKYGDVTYFRIFKEHFILVSSHEAAVEFFEKRSKNYSTRPFSMMAQLMGWNFPTSFKPYGEQWRAERRLLQHHFKPDAMPSYHAIQTRQVNIMLQRLLTEPDEFRNHIRNLAGAIIMSTVYGYDIAPKDDPYVKIAETATSKLGEAMFPGASPVNVLPFLRYFPDWFPGCGFHQSARDTKVVIDAMLNEPIASVQERIKRGINDPCIASQLLSNQDVSIESQVVKNVCSTIYAAGYDTTISAVATFFYAMANFHDVQLKAQTEIESVIGTDRLPSFDDRATLPYVEALFRELLRWQPVVPFSLFHAASEEDAYNGYHIPKGATIIPNIRAMTRDPSRYMEPEIFNPSRFLKLDGTLNDDDVQYVFGFGRRICPGRYFASDTVWLSIVRVLFLFDIQRKKDAFGNYTALDSGYGTGLVAHPLPFECTISPRPRIDKQIILDSIAEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2W2</accession>
    <name>A0A9P6E2W2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_911749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158037">
        <property type="protein sequence ID" value="KAF9521514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2W2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="37876" checksum="62DF17AC5C91B64A" modified="2023-09-13" version="1">MWEADAPDPSVLSSWLGLGLSIVGLYPSLPQPYAISVGALSLILSTVGVYDSTTVVAPAKPETDTLYFKQAMWRAAFRTPKSGVKTTSNAATLIRVHVVNQTKVVITRAQQTYLPQGNVMTSKIFADPGVAKDLFSIIMPDELKILPFRIYEIAGLVPQKGPVTTDNTWFKGPAAVTFTRGELATVNTSTIDRTTLTRHGHLSIEYPKDTILFKYNSSAVLICVKDQQTIGDDGYDFFWIGNTDKLTFLRLSASKIAGLAGKIDIGFISSEDTLKLRIAGRYKGYRVYWIEPRKDPGTNKNADYLCAGNLGPNTTISAADDYPTRRVMVRITNWHSELRTVKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4F7</accession>
    <name>A0A9P6E4F7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_115066</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4F7"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="494" mass="55656" checksum="473FBF2C261D6FC6" modified="2023-09-13" version="1">MATSPLLVSLAVGASVLGVVLSFMLRSTSDGRIVNLGGIPILNAWKFFSKRYDFMSAGFRKAGGLPFSFRILQYRVVAVSGTEARKHFFNDPTLGFVEGYRILIGGPKMEDIDIKTDVLEDISGVHKRLNLLLKRERISETLPTFLEDINRRMLGWGQGSNGSINPFKEVYDLVLQMTVRMATCQEIAKDVDVIKKIDKMYWDIELSSTPTRLLLPWIPSPSKKLGEKAMMGLYLLFLKYVQDGRAAGAETNDPIDVLIRNGDSDNDIVEVIIGAVFTGFVNTGVNTCWALLYLGTHPQWRERARKELDGLISRHTSTSPAGEPFHRLLSSIPFDAWESELPIVDLIIRETIRLSFNVTVPRRNLGKDIVIQDTVVKKGDFLVYSLGDANLNPEIYRNPEEFDPGRFEEGREEDKKVHFGYLGWGAGRHPCAGMRIARLEIKLVLAMLLLGYDYTLVDGKGRPTNVLPKPNRNDIQQARPMGETVYMKFKRVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4V4</accession>
    <name>A0A9P6E4V4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_736498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157945">
        <property type="protein sequence ID" value="KAF9522459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4V4"/>
    <dbReference type="OrthoDB" id="3255824at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="82" mass="9191" checksum="EAC409E5049E50AE" modified="2023-09-13" version="1" fragment="single">IIAVEMGVRALIAAGYQDTTIIVRSDNEGVVQALTKLTWTTNHGLFTVLERIYRLCKRHELKLQAKWVSTKVNPADKPSRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4Y7</accession>
    <name>A0A9P6E4Y7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157942">
        <property type="protein sequence ID" value="KAF9522523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4Y7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="879" mass="94868" checksum="682E8BA977B5D6B4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6J8</accession>
    <name>A0A9P6E6J8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_910689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6J8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="38690" checksum="D530AFAF92740D26" modified="2023-09-13" version="1">MAATPPATLYTIVGIFAIADGREEPVPNKSYPIHVYNSVLEAEDNSKIKVHIHNFGPSLLANFTNVLLIGKVIFPLDPSIVPTIISYKLAPFPGNPSARGYDDYIPSFGPPFIMATGHVSSPVRSTGSEPRSFSMTASTWNNGAPHASSVMCILKNNACWPRAPPLPLRSPLSVVGPACGIIDKHILAISLADTATNLAHLDPILAQRASLGGQPRRKFLAHLKDDEPSSSTPTNVSPVASTSQVPLISSQIDLPPTSSPTFTPNNVPDHSQSDVLPYVTPIKKPRRKPLTKAEKAAAAAAAAIMNTTDPLDPSLFPPPAAPKTPRRKAPAKSVPTLPLMDPVAASPPQQMESPRKRRKQSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6N5</accession>
    <name>A0A9P6E6N5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Gluconokinase</fullName>
            <ecNumber evidence="3 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_839671</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate acid metabolism; D-gluconate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="3 9"/>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6N5"/>
    <dbReference type="OrthoDB" id="275177at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442:SF3">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="227" mass="24989" checksum="80ED665F16AAEC3E" modified="2023-09-13" version="1">MDVQSSIHPNEDIAKVNHDTSLKYLFVVVMGVSGTGKTTLGSALSKALDIPYVEGDALHPRENVEKMSNGHPLTDGDRQPWLELIRKTAVRYTIESPIEARSDKKLVGVVISCSALKRSYRELLRGRVDSLPLPDPVPSDISTPSWKVPQLQTCFVYIKGSRDLILKRMEARVGHYMKASMLDTQLAVLESPEGEDGVIVVDNEASTNDQVKIALEGLKSFVGEGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6S1</accession>
    <name>A0A9P6E6S1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MSF1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_682760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6S1"/>
    <dbReference type="OrthoDB" id="341300at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25376" checksum="902B2838513477BA" modified="2023-09-13" version="1">MRFFSQSYLYDDSWSIVTLAFFLRYPNPYAAHVLSCDVISRDCTPSGTLVTKRLILKQGNLPRWFPKGIVSRAESWVIEESEVDPYGQVVRCTTRNLDHVKVMQVEESVKFAQTTDGKTLQHTEGRVFSRFGWGLTKKIENHGLNKFKANLQRSREGVSVVLSLLRQSRLQPMTLGAGVETPHELSPSVIEGPLSASGSDQHDAQASTSWQRLKSWFQPPSSSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E757</accession>
    <name>A0A9P6E757_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Triose-phosphate transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_862253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E757"/>
    <dbReference type="OrthoDB" id="10261634at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="183"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="533"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="624" mass="67935" checksum="4565756407811055" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7M4</accession>
    <name>A0A9P6E7M4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_877814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7M4"/>
    <dbReference type="OrthoDB" id="5392716at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46177:SF1">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="48125" checksum="57BB8059B2BC8B75" modified="2023-09-13" version="1">MASHNRNPTGRNQYPNAPTLDNKVFVEALKQYHREHISSNKVIKERLSKDHQIETSESNIKNKRNNLGLYGSRSKKGKRTEQEIEQTVLNQMDKDVVDNIGVPTTTARIAFDQREHIPRDKVRAIMKLHRPEGFERRNPGGRKTPRTTVTSIGINERWAADGHDKLNKIGFPIYAVVDFATGKILGAWVVPNNRLGSTVAYLFLSLIEQYKGIPLQFSTDCGSETTMWHGIANALREFFHSDIDIAELAAHNYMKSIHNILSERSWLRLRLVFVDNAVAVFERGVAEGIYDPIIPIQEELCRWLWAKLLRQDLASYVYFQNTWPGRKVPYKATPSGVARDTAYKDYHQYGMDDYLQPLTTEQVDVVRELKELIGGERPLAFSSEEFDVRAQAAYDELEIKQLNTENVWHLFEALLTRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7S1</accession>
    <name>A0A9P6E7S1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7S1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="56" mass="5974" checksum="358CD6FF40B7238A" modified="2023-09-13" version="1">MNGADQPSQAPATTWAALRNSASHEYTPFSTRLVCSMLLTLIGGCFVGGLNVFWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8B7</accession>
    <name>A0A9P6E8B7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peroxidase TAP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_798200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DyP-type peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8B7"/>
    <dbReference type="OrthoDB" id="3207336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049509">
        <property type="entry name" value="DyP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048328">
        <property type="entry name" value="Dyp_perox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30521:SF4">
        <property type="entry name" value="DEFERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30521">
        <property type="entry name" value="DEFERROCHELATASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21105">
        <property type="entry name" value="DyP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20628">
        <property type="entry name" value="Dyp_perox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="DyP dimeric alpha+beta barrel" evidence="10">
        <location>
            <begin position="12"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Dyp-type peroxidase C-terminal" evidence="9">
        <location>
            <begin position="239"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9524199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="483" mass="53480" checksum="A47A17E0DBA71D99" modified="2023-09-13" version="1">MSTTPISLDLNNIQGDILSGLPKKTQYYIFFKIQDAAKFRSDLAHFIPLIKTVAQVLKDRDDIDDHKRRGQPGLIPLVGVNISISHFGFVKLGIDDSTLAPNGTEDVFVKGQKQDAITNLGDPKRADGNPDWEDAFLNEIDGLIIISGESHATIEKKKHEIEHIFGVHTHHASIQEVKSIRGDVRPGDQSGHEHFGFLDGISNPTVNGFDTNVNPGPKSVDPGKVLVGQTGDPTPTREDWAKDGSFLVFRYLFQLVPEFDKFLEEHPLKKDGNGKDLTPEKGSELLGARMVGRWKSGAPIDVSPFQDDPELADDPKRTNDFKFEGERTSQLKCPFAAHVRKTNPRDDLEPDFSIDDRRILRRGVQFGPEVTRAEHNSGKTIHDRGLLFTCYQSHIENGFQFLQQSWANTANFPPFTGIGNATGLDPLIGQGDRAMSGLDPLSPQNVLPIDTFIIPRGGEYFFSPSLKALKENIATGVQFTVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8P4</accession>
    <name>A0A9P6E8P4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_897817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">CBS 506.95</strain>
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    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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</entry>
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    <name>A0A9P6E8W3_9AGAR</name>
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        <name evidence="1" type="ORF">CPB83DRAFT_860862</name>
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                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
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                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
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    </evidence>
    <sequence length="410" mass="48163" checksum="37AC3BF3BD09C7C7" modified="2023-09-13" version="1">MAYPTVVALDTDGTIWENYLDSKRWGKGARAQVKIEDNIDRVDRRLLRDKTNHAFWIRIHNEISMVVTDILKHGAKLAIVSRNPSKALSDRALYYFKTINPKDNKEYGIIHLVNYDEVKNETKILPFNRIHGWSKSDYQDMLMFDDEAFNNCVRIHLGVSFQFIRDKKKGLTWASYQEGLKAWRRSKNLSIAPSPGFVPRRELIGFSGLPTYWINLVNRREGTVETKVPYRWGFALYVADNIEIAKYFSGWNGNFVPDVKSYVCEVWTKDYDAWMRLNKIWVPEHSGALMQMNNMHWSAEQTGKNQEDRDHTIATNWHVYAPYVLFSQHHWMKGMPGQPKQRWPEMVVYTQIQRSLIEIVQLSTDALKKVANHQPHPFHRQFKTWHITAPPPTRQEFLKYGEKDVYKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E958</accession>
    <name>A0A9P6E958_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">CPB83DRAFT_909652</name>
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                <person name="Riley R."/>
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                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
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    </reference>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9H3</accession>
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                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9H3"/>
    <dbReference type="OrthoDB" id="10262609at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="598"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="611"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="663" mass="72302" checksum="7AAE40726AB96501" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9H5</accession>
    <name>A0A9P6E9H5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9H5"/>
    <dbReference type="OrthoDB" id="3147752at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="665" mass="75050" checksum="E81990BD390E4576" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA49</accession>
    <name>A0A9P6EA49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_909050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA49"/>
    <dbReference type="OrthoDB" id="4584900at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040161181" evidence="1">
        <location>
            <begin position="22"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="28188" checksum="1F23A67237B6D689" modified="2023-09-13" version="1">MSLTRVLAALFALSIFGVVSSAYTGATSTSGLDEFTGIEFHHAPSPRSVYPGISNAERLKRGLPLKPPKRRASHVIHAPRPSATPVRGRVQAFDAYTGAPIGFISKNPSSAGVAGLTPVFDDAMVFQYDKSTSAPYDFTMVNPASYFAQFPLLGNVLGPSSISQTLGPGLYNYCFFAGTNETPADSPPVVQGTSFSTTLGAETAVWKKTDSGDISLQWVNPDGSKPETFVMYAPSANSLAITGDVAAYLDTFGTGRFPITLKWVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAT1</accession>
    <name>A0A9P6EAT1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAT1"/>
    <dbReference type="OrthoDB" id="3227921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="623" mass="69377" checksum="F77569B34856C0B0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB16</accession>
    <name>A0A9P6EB16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_859184</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB16"/>
    <dbReference type="OrthoDB" id="420606at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="472" mass="52647" checksum="3C2D030F2C8267A8" modified="2023-09-13" version="1">MLDQKAKVRLNFVVVGASLAGLASAYTLAKVGHKVVVVDVVPDIPLSYGTIGSSPSMTSILVQWGLQKQIDELFQVCNNCRFFSATTGDFLGCLNRSLMEEIKSDGTAGFMIAYYNDLHRLLREIAAQAGAQTLFNSLVTGLDPTTDNVMLATGEILEADLIIAADGCHSLFRRYIVDEHPEHEELLSLIPPRFVHMMLPISMDKVREDKDLDGILNPISWDYWLGDGYICHGNVSNHEQNSLFAIVQPFSGEEKPEHKIWTQSSDFAAYGVDYSGLDIRVQKLFGMASDFWAKIYENRPLETIVGASPKVILVGEAAHSILPGSYHFPALAFEDAQTLGYLFSKIQDKGQISKFLAAYEDIRQPRLKFVYESELKYRVGLTSPDATLRQRRDQLLKRLSEYNASTSPADVETLMTDWGADFEIMSYDATVHVTDWWRQYGSSIVGVSPQLNGPEDELEIGVVTEVTEHVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECD1</accession>
    <name>A0A9P6ECD1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_496246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECD1"/>
    <dbReference type="OrthoDB" id="2688364at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="278" mass="31199" checksum="595B7D440540FBA9" modified="2023-09-13" version="1">MGQLPSTLGPWSRRCTFIPPRDGYIHSRKSWRQCVPTEQRCLHYGTIKIWKPTFGDCESKTTRGSATAWNVSMPGGHKVDAINLFGSRIFILKRNQIVQWAPGSIPGIRLDSSPVDLLRARQTCKHIRDASLRHTVWAQIMYQIMLQHNIPAITFLPKLNQQTLEHLSLSPRKFRRKLEAGFDSGPKTISPVSAQYALYDPPGAKLAALGIENLLPYQWLDVCPGGRFLFTFRVVQKANGGSRTANFIQLWDLGTVGALYYPRVAACLVNPSPGAHQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED42</accession>
    <name>A0A9P6ED42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7223 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_794315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED42"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055647">
        <property type="entry name" value="DUF7223"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23865">
        <property type="entry name" value="DUF7223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040191419" description="DUF7223 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7223" evidence="3">
        <location>
            <begin position="300"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="552" mass="56984" checksum="4CF9EFFC63749B64" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDF6</accession>
    <name>A0A9P6EDF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_856982</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDF6"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="292" mass="32115" checksum="750B0082D64ED793" modified="2023-09-13" version="1">MPTTFTLNTGTQIPWLGFGTGTALYSKDASQLVRQAIDAGVNHLDGAQMYNNEETLGTGIKQSGKPRAELFITTKLNGKVLQPGQTIKDTLQVSLQKLGLEYVDLFLIHDPTPATKQSNETLIDWWKQMEGVYADGLAKAIGVSNFKVSDLEIILPGAKVIPAANQIELHPYVWQEAEPIVRLCHEKGIVVESYGGLSPIVRVPGGPLDPTLETIRQRLAKDHGQPVSAGQVLTKWLSAKKAVVVTTTSKVERIKEFQDLPKIPDLTLEEVKQIEESGAELHKRSYMGHVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE66</accession>
    <name>A0A9P6EE66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 8 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_856092</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE66"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000044">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="176"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9527400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="401" mass="44328" checksum="06A9190E85A9C688" modified="2023-09-13" version="1">MPAGGSLAIAPGGIKSYYQAKIEGAEILINQKTQNLRRLEAQRNALNARVRLLREELQLLHEPGSYVGEVVKVMGKTKVLVKVQPEGKYIVDIDAEIDVNALKATLRVALRSDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCKFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRGDSGSGGGDSEVQRTMLELLNQLDGFESTKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPGPEARVSILRIHSRKMSLQRGINLRALAEKMGQCSGAEVRGICTEAGMYALRERRQHVTQEDFEFAVAKVLKKNQDSNTSVNKLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE71</accession>
    <name>A0A9P6EE71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE71"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040192301" evidence="1">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="126" mass="14551" checksum="DB308DD8891026A0" modified="2023-09-13" version="1">MWGVKRFGVRMQFSLGLVLATIPLTAQLARLKVEDVPFSPKRLSSPRKEYYSQDVQPLRDTWHDLVRPFLIYPPATKPLISNFSHSPLSSLLLPPATCHLPHLLFSLHFIPLVFSTYHPHYMPYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEI3</accession>
    <name>A0A9P6EEI3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_907191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEI3"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="20348" checksum="987BEE9BF7672748" modified="2023-09-13" version="1">MSQAVGNTALAYTRVWHQVDASERVLGKLAERIALVLMGKHKPIYDPSVDCGDYVVVTNSRKIKVTGRKEEQLLFRKHSMFPGGLKETPYATMKQRNPDEIIRHAVSGMLPKNKLRERRLERLKIFPSYKMGRIGANIMRTFQDGTIPHDYDPSKPTTSQTLERLRQKKALAEVQETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEV6</accession>
    <name>A0A9P6EEV6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEV6"/>
    <dbReference type="OrthoDB" id="2692698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="642" mass="70160" checksum="7314CB867126FBC9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFJ6</accession>
    <name>A0A9P6EFJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PUA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_814455</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFJ6"/>
    <dbReference type="OrthoDB" id="41445at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21133">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.590.10:FF:000006">
        <property type="entry name" value="Chromosome 7, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052181">
        <property type="entry name" value="5hmC_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047197">
        <property type="entry name" value="THYN1-like_EVE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087:SF7">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="4">
        <location>
            <begin position="4"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="293" mass="33067" checksum="42AD0903C6896174" modified="2023-09-13" version="1">MEHKFWLLKAEPDSRVVKGKDVKFSVDDFESTKMSPWEGVRSYEARNIMKEMKVGQGALFYHSNCKTPGIAAFAKVTKEAYPDYTAWDESHPYFDPKSNPDEPKWFMVDLTFSSRAQNFIPLALLRLIADRPNSDLPEEISYIGEKGASAIKSMDLIRKGRLSVQRVSREAWDTIAQMAETGGWTDLDLKPKKKPFKVKSVQDDVGDDESTLGPPKSKPPRQRNTSKQASSGSTAKGTSKAKQSTSEESQDEEEPVRSGIKGKPATKRKRIETDIDDQEETGSTLRRSTRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFL7</accession>
    <name>A0A9P6EFL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_894716</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFL7"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024119">
        <property type="entry name" value="TF_DEAF-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237:SF14">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1179" mass="130917" checksum="B78E1D14AA1FD8B9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFV2</accession>
    <name>A0A9P6EFV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_894504</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the polysaccharide monooxygenase AA14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFV2"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054497">
        <property type="entry name" value="LPMO_AA14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22810">
        <property type="entry name" value="LPMO_AA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040216609" evidence="13">
        <location>
            <begin position="21"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="290"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="375"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="457" mass="46605" checksum="E729D99FEC1EE72D" modified="2023-09-13" version="1">MFNTAAIALSASFLVGVAKAHLAPWAPGMYCSLGNTGTPDLNSYAIVKPLYQLPFDQWWMHHTDNCDAFPPPDGEFLELPAGGSFTVEIASNRAKTTLSYGNRDTSEWPDGAQYPEDYNVPSCITSPNMHTQNQANAAGTAFAIAYKSDIKAVTPGDLTVFSIVEHTPWKRVTSYDVPAALPACPDGGCICAWGWVPNGCGQPNMYMVPFKCKVTGATSTTPVAAPKPPVWCENQPDQCTPGAKQMIFWNQADGNNIVTDGLDASGQPKSPGYNMKLGFTAGPQNNIFVGGPSAAPAPAPAPAPAPAPAPAPAPAPAPAPPTQNTNAGNGNTNTGNGNTGAGSGNANPGTPAGGNTGTGNTDAGGSSPSSPPAGPNSTPAGANSAPAGTNPTPAGTGSTSSTSDSGSSSAPLPSTTKQSTAKSCKKRSARRALRAQAKRSLSGAASHHHRRQANHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGT7</accession>
    <name>A0A9P6EGT7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_299478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGT7"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044508">
        <property type="entry name" value="At5g50450/At1g67340-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46758">
        <property type="entry name" value="MYND DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46758:SF2">
        <property type="entry name" value="OJ1485_B09.11 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="399" mass="44505" checksum="EF9DC6A12415B88F" modified="2023-09-13" version="1">MVTHRIGEEARIGNLGGGLVSAESHRNLIKAEDLCRRGKPEQCVPYLMKALEDVHNLDAVIQMAFLAPGHRPEGIEILEQGEEVGRKLLKTALGEKAFDDNGGSVGRFWLIIQTRPYMRLLQALVRMYFEEGRYADTARTIEEILRLCPGDNLALKHWLGPMLNQCGRHSDALFFSQAWWHEGIFPARGGTAFTTPNPEVPASMSEDAVQFIPCSLVYTAALSSFKFFGDCDQSRTYLKMSAISNPGVLLKILARVQRPANLNFDGRSMNGAEDAQDYLCQTQNLWMEDDIWNWANQSEAKSLILKICSRAHCEVKEKRVAEFKRCAACHKASYCSQTCQKLDWPTHKPGLSDCLAHKQLKATMRTFMAGKSAKDGSVPVVGTDTSELGTSIFTNVDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGU5</accession>
    <name>A0A9P6EGU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_883358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGU5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="251" mass="28027" checksum="35F7246BD7BE277A" modified="2023-09-13" version="1">MIKTRQRKLGHLEISCNRAPDFDQAFGQRTRHAILDLIPHSSPAYVNLLITKSSSNRGHTQLTTLLSGSTCTLRVLEILLIDSQLGYEVNPDTIRFDFSKFSKLSTIRVKYDALVFGSACGFFAQVQWHLAFAVTFLASAPSLSCLAESLFEIRLIGLVQHFDGCEEMISSVQPVNELNRKGLLARHPNLKSFDITVVLQFLKGYLPGNDALALQNVIRRCIKKSLPNSAHLPDFQSSERAAVFKISLDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGX0</accession>
    <name>A0A9P6EGX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DYW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_883399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGX0"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032867">
        <property type="entry name" value="DYW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046960">
        <property type="entry name" value="PPR_At4g14850-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14432">
        <property type="entry name" value="DYW_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="336"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="DYW" evidence="2">
        <location>
            <begin position="494"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="566" mass="62640" checksum="F2D6F76D40534E8B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGZ6</accession>
    <name>A0A9P6EGZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGZ6"/>
    <dbReference type="OrthoDB" id="2688210at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30730" checksum="0A4090565FA64256" modified="2023-09-13" version="1">MGTGRERETGARERVRQEEERNLQEEEARAREAEEQRLAEEQRAVAAQEAARLAATRNELPVTPVKKKFRDFKEGSVVKSTPALARPSSYALKKLTDHEYVEMWYFTTEACRETALYERSTSHKAFTMSNVDGVMAWKSLNAHKASSKAVPDAALTWNQVSLAKNKFISCIIEKSWPNEHVESLVGLYTGLDSHPIREQEGGDQAVSQYHAEVRREWMDAVTSATGAEPFDISMINQARLQAIYAKQLTERQLNAIKRSVNQFIQLRISAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH08</accession>
    <name>A0A9P6EH08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_883125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH08"/>
    <dbReference type="OrthoDB" id="3351617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="37724" checksum="DF6D4764467BFF67" modified="2023-09-13" version="1">MASEITDLDAKVDVFLRSLYAEVCVSCASIGIQLFMCIYGLSVLLETPKERRRGREIYVAISFGILILDSFSKLPLTSYNFDLLNKPTSADDLISLQDQLYLTWYMIGSDWATVLLFWLGDGMLVYRCYIVWTGRRLITIVPLAIYLGSLAMSLWFLRMTTGGPLDAVYKAWVSLTVAVNCTVTLLIAGRLLYMRWQQKAVLASFDSKMYLSAISILAESALPLAFAGILVTITKGAYASGAWRPWKIADNVSILLWETLAALSPQMIIFRVTMGRSWAHSSQKSTQISTLAFQPNTVDHGSAGTDFDEESVPQEKQNIATSQEIKDSTGPFASQEVSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI82</accession>
    <name>A0A9P6EI82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_906101</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI82"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="13">
        <location>
            <begin position="5"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="465"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="810"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="963"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9529439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1017" mass="112084" checksum="9E4DAE5CC362ACC7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIB7</accession>
    <name>A0A9P6EIB7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_869061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytoskeleton</location>
            <location evidence="6">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIB7"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="21402" checksum="8E42BBC5C3CC7888" modified="2023-09-13" version="1">MSNSLRPYLAAVRSTLTAALTLENFASQVVERHNKPEIESSTSKEVLLNPLTISRNENERVLIEPSVNSIRLSIKIKQADEIERILCNKFTRFMMQRAESFIVLRRKPVTGYDISFLITNTHTETMLKHKIVDFIIQFMEEVDKEISEMKLSLNARARIVAESYLTAVRSISLLRCLQLKSPQFNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJC5</accession>
    <name>A0A9P6EJC5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_882000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJC5"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="192"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="669"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="921"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="550"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="940" mass="105318" checksum="7099B6CE0A0EE650" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJN4</accession>
    <name>A0A9P6EJN4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJN4"/>
    <dbReference type="OrthoDB" id="2986975at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11136" checksum="4F5C801ADD6837E2" modified="2023-09-13" version="1">MDASRSDNSSGFYNGSMERRGSYYIPQYRSQQMKRETLQGYRKSKIYCMDSKRTGKLTDRVEIAIGMKIMVVLNVATEANIANGTRGTITDIILDPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJR5</accession>
    <name>A0A9P6EJR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome 60S biogenesis N-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_149046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="72892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059018">
        <property type="entry name" value="HEAT_URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039844">
        <property type="entry name" value="URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021714">
        <property type="entry name" value="URB1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500:SF0">
        <property type="entry name" value="NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500">
        <property type="entry name" value="NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26140">
        <property type="entry name" value="HEAT_URB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11707">
        <property type="entry name" value="Npa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="URB1 N-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 central HEAT repeat" evidence="4">
        <location>
            <begin position="664"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="URB1 C-terminal" evidence="3">
        <location>
            <begin position="1649"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2063" mass="231969" checksum="08F7E66C710848BB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK42</accession>
    <name>A0A9P6EK42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_810742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK42"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="31658" checksum="1F1D166AF1AF7637" modified="2023-09-13" version="1">MQFFSAFTMPFSPAYTAVSNEALDEAFLSRENISIIEEKGETTAWKQNRRPLSRIFYAFPWFLSFILLVALIWMDQSRRASYCEITFGFDEMVYSPAQDIIEPQNVVFTSGFVPEVSIYQGPSSPERDQAWEDLYSYGISRIPKSSAARLVNKTVPIPDDPDHYVVMLKVFHQLHCLNMLRLRLWSNGTFDPSNILMSMDHLSHCMDSLRQALMCSSDITPIPWSWNYETKEAKPVADIQHSCRNFNKVKEWARENHVKSFNPKVYVEDDLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKX1</accession>
    <name>A0A9P6EKX1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_850040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKX1"/>
    <dbReference type="OrthoDB" id="1731724at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036435">
        <property type="term" value="F:K48-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000005">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23625">
        <property type="entry name" value="UIM_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="245"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="372" mass="39472" checksum="F8BA3FC5C2E4CEA8" modified="2023-09-13" version="1">MPLEATMIIIDNSEYMRNGDYMPTRFAAQADAVNVVFQTKIDSNPENTVGIMTMAGRSPEVLVTHTKEHGHILGGVHSASKKIGGSIDLPTTLNVAQLALKHRENKNLRQRVIVFTASPLETDQDTMVKLARKLKKNNVAVDIVVLGDAIGEDCGETVLRAFVENVNSTDNSHLLVVPPGNHLLSDALISSPILSADRSAAIPEELGGTGAGPSGPGPAPSNDFEFGVDPSLDPELAMALRMSMQEAQAREAAQAAASGATTSAPSTTTPAAPTGPQPTVVPSQRGPHPGANSADDVDDDEDEDDEDEELQAALALSKASTSAAEEDEDEDEDEDVEMEDDDEGDEDDEDEEDDDEIQKAIQMSLQKPGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELG1</accession>
    <name>A0A9P6ELG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_914447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELG1"/>
    <dbReference type="OrthoDB" id="2564232at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="92"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="29568" checksum="9AB017181C3661FA" modified="2023-09-13" version="1">MSKSDAVAKIRPYTASDQKLVRFKLGQSNMEALANANNKTYFHPLTLAVWVALSGAFIQMMQWWPSSQYGILSYLKPLPAFASTAVPVMFFVDWINRPYFEGLTQEVMRRPDVRDIEKHYFHDPASGFWLLEFGDKYIGLIAVDASQPSSKDKRNAAKANGKTPKTATIRHFHVDDEFRKANVQQDLLDYAVDHAFNKDPKLERIEVPDSPLIPYTRPTLRDKGFELDHHTQTVGILGWKMGTRYLKREKWSDSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELT7</accession>
    <name>A0A9P6ELT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELT7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="55" mass="6133" checksum="F191669436A2E7C2" modified="2023-09-13" version="1">MIAEATRVNASPMTMGAGFICQVHYPSITFFSRCDALLRMGENAPWLVHTGRYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMG1</accession>
    <name>A0A9P6EMG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Antiviral helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_903977</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMG1"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000987">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="287"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="555"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="510"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1238" mass="138255" checksum="E3EA01927015CBE1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMI3</accession>
    <name>A0A9P6EMI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ASTRA-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_806876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat ASA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMI3"/>
    <dbReference type="OrthoDB" id="7668193at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="403" mass="44642" checksum="49C2D2F1283A294C" modified="2023-09-13" version="1">MEQPLPPTPLHLLRVHSSPVTAIAYSDDNERIYSGDTSGKVVVTSTRSLRAIASWNAHTDSVLGVEEWDYQVITHARDNKIHVWGRMEEPPLSSRIGGVAGISDMQATTPKHCYSMDVNALNFCRFSLLKASTGQQLGLIAVPNLVDSTTVDIWSLPSQERMHAAVGQEVSKSLFSENPGARNNSGIVMSIHVYRNLITSSEPSSSSMTGNLRLLAAYENGSVVLREYTRSSKDMSVEGRGWDVIWKFKLHVETIMAMKVSRVNYFALTVSADHIIGYYDLTEDKPRDSRGVAHRTKHPGNGSVAIRDDGKVCAVGGWDGKIRLYSTKSFKPLGTLRYHKEAAQCIQFSRSLYNPGCAGDVDIEDDDSEDNLTQAEQMERSGWLLVGSKDSRLSIWSLIDFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMR6</accession>
    <name>A0A9P6EMR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane proteins 14C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_848632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMR6"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="10404" checksum="7CAE23D04B4D17E0" modified="2023-09-13" version="1">MSAYPAYTMGGLCIVGGITGFARTRSIPSLVAGVGVGLIYLWSADAIRKGAANGLEGALGASALLLLSSIPRVSKGPVPATLAATSALAGFYYGSTVYNLRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMX8</accession>
    <name>A0A9P6EMX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_891895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMX8"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="151"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="60"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="288" mass="33406" checksum="83C543125C535A1A" modified="2023-09-13" version="1">MRPTISTTSEIIELTSSSEDEKSNKDSLVTARRQLRDWKEKAKHDKKRLDAITKDMSILRADQEAKLEEALREVARIRVNQEAKLEEASREVARIRAEHDLKIAEIAEVFNALNSGHEEEMHSAAKDILRLQSLLEMSFKKNEELLELLECDICAHSIARPFTLKNCGHTFCYSCLRGWFLVLREEFRLKHPVYDPMHRFEKLNLATASQLAQTLAEDYSDFVHQVTLEDVLPHALRRYPHYSCPLCRQHVHSKPVEVYTLKAVIPLLREVGNSDHETEGQWAEFFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENL4</accession>
    <name>A0A9P6ENL4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_785638</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENL4"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17971">
        <property type="entry name" value="DEXHc_DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21691">
        <property type="entry name" value="GH2-like_DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05684">
        <property type="entry name" value="S1_DHX8_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000061">
        <property type="entry name" value="ATP-dependent RNA helicase DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000101">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000191">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044762">
        <property type="entry name" value="DHX8/Prp22_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049588">
        <property type="entry name" value="DHX8_GH2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049621">
        <property type="entry name" value="S1_DHX8_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="12">
        <location>
            <begin position="194"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="503"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="684"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="138"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9531894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1155" mass="129680" checksum="A14A997AA3EE1A32" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPZ0</accession>
    <name>A0A9P6EPZ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_804836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPZ0"/>
    <dbReference type="OrthoDB" id="3261578at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="503" mass="55147" checksum="E6D8A466D152CDF5" modified="2023-09-13" version="1">MTAAIRPPLPPMPPSYAATGSHDPPSLPAYTPSLRAPRPPSRLSMRSRRTTGPRKSRSKEFNFDLKRKGKTFAGMTIMADSPLAKTMPVIVEGQPVKGFARLALDKPKSIQTISVHITGQVITGLNQGEQLCFINISETLWSQSMGDPRLAASRYSPECTGRKASFGQHLTVSPKTQGDLSPSSSRSTSKTSAKFAGKIPAGEYFWDFSIDLPKEVLLPATPGGKPQLFHPPQSFNERHTRASVIYEVLVKFGRTSIFLSDHRVATPFGYIPVTYPPPFPPLRASAYQDHTPLLPPAIDPDGWHAVEPVKVSGTLFNNRTVNIRCSFFLANPLSYTRSTIIPLCLRISCDDDQALALLSSPNAVVCRLRRRVKFHANPEKMVDPLAWRDAIDHSQLAVWRHDRHNAAVDAGRGSRVLQGELHLRQDMKPSSAMAQFRVEYSVVLFPFDAAGFEGLSSDQLAEQPVEIVTAYAAGPRPRMNAPPGYDTDTALQPGAPGLNVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ76</accession>
    <name>A0A9P6EQ76_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_527207</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ76"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF156">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="41224" checksum="62BC8A5C9B87593C" modified="2023-09-13" version="1">MSKKSTQKKRHTKPCRYFQLNKCPHPADVCDFAHVFAPSSAPVERCTTMCRFYSISQCPNGPLCVYQHYDEARSSSTTDWGTSPSDTTDPIYGGYPAYGQVWPPSSFPPSNLAPFPPHVVESMLFAPPRSRDSIETATNSISSLDSDEMIVMTDDPQYPEHTHSHQSQVYIAEDSPIIHVPPFYPIGGVQVGPSGMISPIGTGPFDWGLAAGMANGAMKKPDLRPRSSTRSMSKQKAMAFKTKPCKFFNTERGCPNGNTCTFVHEEDRPGSPLPQPASPVKYPTLTDDSKNYYPITWRVIGGGVRVGMTRDDENRPPAYDTAESSEHTSTPHEKPHLPALKMMTRQRSNSIPSTPSNIQVKVDQLFPAESPGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQT5</accession>
    <name>A0A9P6EQT5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQT5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6624" checksum="41E189F7E353CA1C" modified="2023-09-13" version="1">MILRTLSIYFVSELVCYQRPSSLLILSHTFSALYLLHVTIPLVLHIIWPLSSNSNHAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER32</accession>
    <name>A0A9P6ER32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER32"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="95" mass="9958" checksum="C65193D76EBC6C13" modified="2023-09-13" version="1">MAVAILREGTVKPNDPAAPPDVSTHHPRGPSLKIASTQVFTPPTQVARRDGPEAFYHSSPTSSGTHYHAKGDKEDNSTALASVPQKSATISEPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERD4</accession>
    <name>A0A9P6ERD4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA repair protein REV1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Reversionless protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_873629</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERD4"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17719">
        <property type="entry name" value="BRCT_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01701">
        <property type="entry name" value="PolY_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19318">
        <property type="entry name" value="Rev1_UBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000001">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000011">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1280">
        <property type="entry name" value="DNA repair protein Rev1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053848">
        <property type="entry name" value="IMS_HHH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031991">
        <property type="entry name" value="Rev1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038401">
        <property type="entry name" value="Rev1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047346">
        <property type="entry name" value="Rev1_UBM1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21999">
        <property type="entry name" value="IMS_HHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16727">
        <property type="entry name" value="REV1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="17">
        <location>
            <begin position="129"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="UmuC" evidence="18">
        <location>
            <begin position="401"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="36"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="794"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="867"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="806"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="889"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00081902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9533654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1168" mass="129814" checksum="CF854AC3DA47A2DD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERM7</accession>
    <name>A0A9P6ERM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_866181</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERM7"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF5">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040321322" description="alpha-1,2-Mannosidase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="9">
        <location>
            <begin position="746"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9534836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="884" mass="99746" checksum="73E840F00CAE3D8F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERR6</accession>
    <name>A0A9P6ERR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DOPA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_783402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERR6"/>
    <dbReference type="OrthoDB" id="9970095at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="22034" checksum="4FD3BADAD1E818EF" modified="2023-09-13" version="1" fragment="single">MKMSGQSVISSFAKPPTDLQYVVDNEIKEWHFHIYFHQNNTQEHSEALQLRDAVLRLRRDGAFIAVPLFRVNTGPIGPHPVGSYEVWCPAETFASVFSYLSMYRGNLSVLIHPLTRDQKRDHESRAAWLGQPYPLDTSKLPVRSEDIPSQYHSLQLGYAAQPSLTLDQRRKLGENVEHILTKEKEAAKAPPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES49</accession>
    <name>A0A9P6ES49_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES49"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000016">
        <property type="entry name" value="Glutathione S-transferase F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900:SF3">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01154">
        <property type="entry name" value="Main.5:_Phi-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="91"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="216" mass="24755" checksum="FA5960F4E46D5F38" modified="2023-09-13" version="1">MVLKLYGNAVSPCTHRVALVLNEKEVPFEFHSIEFAKIEHKSPSYLEKQPFGQVPYIEDDDGFILYESRAIALYIATKYPDQGTKGLVPTDPKANALFHQAVYVEVTHFDDPAAKVTFEKNVKPKYFKGPVDEAYIEKLSNTLDAKLSVYDKILEKQKYLAGEELTLADLYHLPYGVQLAPIGIKNLVEKPNVSRWFKELEERKSWLDVKKTFNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESF7</accession>
    <name>A0A9P6ESF7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein RLP24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_801509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESF7"/>
    <dbReference type="OrthoDB" id="10262490at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000001">
        <property type="entry name" value="probable ribosome biogenesis protein RLP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_eL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF8">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="TRASH" evidence="6">
        <location>
            <begin position="6"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="174" mass="20297" checksum="EE16A971518D0440" modified="2023-09-13" version="1">MRIEKCYFCSTNVYPGHGSAFVRNDAKYFRFCTSKCHKNFKMKRNPRKVRWTKAFRKAAGKEMTIDSTIEFEKRRNIPVRYDRELIQTTVQAMKRVGEIKARRERAFFKHRMAASREKHKAHRKKVLEATKSKSSVKLLEPLAETPVKEKIKVAVIAKSALIQGEGRSMGMEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESV2</accession>
    <name>A0A9P6ESV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_902708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESV2"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="19341" checksum="E6FA6B08160324B4" modified="2023-09-13" version="1">MSPTLRKFATDPNTFVGNDFFDCLQACTHLTSLTSQRSSSYAIPPLDDSPANMSDNLLSRLMSPNEEGEYLCPLLDTLECCEPPDFADKALYEFISRKQSGSIPGISKLERVNNYFNRVATVPRTEELETFIKQGLSFEVTYTAPPLPRNQFSALDGLPYSLGSSSFYIKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET61</accession>
    <name>A0A9P6ET61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin cytoskeleton-regulatory complex protein SLA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_879575</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SLA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET61"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd11773">
        <property type="entry name" value="SH3_Sla1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.700">
        <property type="entry name" value="SLA1 homology domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056996">
        <property type="entry name" value="PH_SLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007131">
        <property type="entry name" value="SHD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035800">
        <property type="entry name" value="Sla1_SH3_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24081">
        <property type="entry name" value="PH_SLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03983">
        <property type="entry name" value="SHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="8"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="75"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="316"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="293"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="376"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="684"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="843"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1012"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="397"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="739"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="788"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1049"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9534358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1076" mass="116372" checksum="7BC13890A4D85FE1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETG5</accession>
    <name>A0A9P6ETG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_901974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETG5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="487" mass="53687" checksum="BC8BAAE6056A14DC" modified="2023-09-13" version="1">MSQGTKSRNMRRSVRTGVTNSSDPFESTPNLLAKARPRGTFHLDPSPSFGRGLENIPRFPSANGDLCGGKMKPTLQTCVVVPDNPHRFDLLPLNKVGKLSGQSEPESAHLLAHLPVPLKHQLPPSPSGRSIGAYAQTRSLQPSGSVLSLDKSAMNDVRACDSYNASSPPPKATGRYSKDAPRSADYHSGRQVLYPLDLNQHQWASPKASEEKSTSSLYHLHKTTEPRAQSSTSTSSRTASQNRFRSESLSSQATRSSNHHYRSTLNYSNHTAPNPNLSSHSTLASAVQLSSDMPSLRRPHTLRSAPLVATSKREHAKNEAKLKRRHAVYHTVPFKIEPDDKLVSLSKSDRDASDSENGKSTASICGSPRPSRTHEPAKQESSHGLDYQEAIATNSLRQDNTPKKSILKNASQSTPKATLSTKSLSKENIPRSKSSQFRLLPPMPLQITKKPREGPKPEYRARKPGSPHPFLDMFLLIDELMCEWERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUE5</accession>
    <name>A0A9P6EUE5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL/TRIO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_842170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUE5"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="105"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="37994" checksum="FE08DCC940B010E9" modified="2023-09-13" version="1">MSPSPISKTTNLLLSPAPDTIIKPIYDYTDNQRAMLDELREYALSISLPESDPYHPWELRWLNKSDTIPRYMRAAKWIVADGKKRIQATLEWRREFKPDLIPPEEVKIESETGKIIINGFDKDGRPIIYMRPGRENTETSPRQLRHLVWCLERAKDLMPPGQESLVIIVDYKSTTLKTNPPISVARKVLTILQQHYCETLGRAIVTNLPMLLSFFYKGISPFLDPVTRDKMRFNPDLLELIPASQLDAEFGGDNHFEFNSEKYWDQIVAACGVATDGTRVESSSASDDETVDGRNSPHSSATASVDETYHSNPDKTDVTVNVEPATHASHTEIAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUG6</accession>
    <name>A0A9P6EUG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_221332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUG6"/>
    <dbReference type="OrthoDB" id="3232130at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="21581" checksum="326D06BCD5057484" modified="2023-09-13" version="1">MEVLMDRLSDYTEMPAELHSAVKPTSETPPRQYPAIVHAAVFTALIVPITLLPYLVAQRQISRLRRTVTALETQVVSLQSDLHLMHTKAHKVVMEQDVARNASERSMKADILRLLDDSQHSRNHAATLKALGVSLGDVAAFMQEVELDFGMDSSPGKDRRGIEKLRLLAFHMQSFKSQSEKTKATAQTDDSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUP9</accession>
    <name>A0A9P6EUP9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromosome segregation in meiosis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_841536</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays an important role in the control of DNA replication and the maintenance of replication fork stability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CSM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUP9"/>
    <dbReference type="OrthoDB" id="437078at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040038">
        <property type="entry name" value="TIPIN/Csm3/Swi3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220">
        <property type="entry name" value="TIMELESS INTERACTING-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220:SF11">
        <property type="entry name" value="TIMELESS-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation in meiosis protein 3" evidence="8">
        <location>
            <begin position="172"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="279"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45128" checksum="6C81DC2AE3D4C6AA" modified="2023-09-13" version="1">MDDSIWDAPLAQETPKRSAGDFSRAGDDGTPSRPTKRARQTLFLVNSDDDDSFDPSQAGPSSKSKSNRNSRAEPVDKPPPAQDLNIEELFADFDDDDMEISKPLPALVDEEELTRRAEAKYKRINKEKEASLHQIMPSSSPGRESDAGIGSKKGKRKEKGGEEKKARKRQAKLDENLLLGPSGFPQLVKMTKDFRIKGKGYEAADLDRLLKVYQYWTHQLYPKTTFSDTVERVEKLCHTRRMNVSLSVWRDQAHGKPIQLPEDDEEDGEEVDVIVDDGELRTSKTHDLPPSSPHRPSSRGSSPPTDAPDADEDDEEFWKSLDMGLPGGGAPMEEPLSDVPPAPPTSSGAPSDMDEDEDMWDIVNQIEQEASGPTGTGDVENSARASGFAAGALLNKPHPKDDWDDMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVF5</accession>
    <name>A0A9P6EVF5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_754377</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVF5"/>
    <dbReference type="OrthoDB" id="165352at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="582"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="416"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="635" mass="72043" checksum="358C8D33089272C7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHY7</accession>
    <name>A0A9P6JHY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_778462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158018">
        <property type="protein sequence ID" value="KAF9521599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHY7"/>
    <dbReference type="OrthoDB" id="3261222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="11135" checksum="5CBE3AA3DC1955EF" modified="2023-09-13" version="1">MQRPTMTIQGHIITPSPSAKFLGVHIDQGLKWKEHGAATIGRGTGWLAQYKRIAKPASGVIHRYMCQLYFSIALPRMCMQLTSFSHHTSDKFQHGQLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ74</accession>
    <name>A0A9P6JJ74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ELYS-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_871877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ74"/>
    <dbReference type="OrthoDB" id="20729at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025151">
        <property type="entry name" value="ELYS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13934">
        <property type="entry name" value="ELYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELYS-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="207" mass="23708" checksum="0056E77E4FAECBD8" modified="2023-09-13" version="1">MDDTLIFDILLTSGGVGDPYVLYPPESPEGLQRLLDKIESSNYDALKKDCLVYFLLKWHQDGRERHFMDQRCIPPQFVALADAYWHLDTGVNLPRAVALLSDPRLNRDYSSKIIRTISLLPDSAPLIRRYIQTAKPLLVEPPDIDTYALALADFSILEAWQFSRTFNEVDPTRERLLRKILECFPLPVSGDTADFNDYAITPLRSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJK5</accession>
    <name>A0A9P6JJK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_911038</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJK5"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="505" mass="56116" checksum="3F8C82F3A35AE0ED" modified="2023-09-13" version="1">MLESFHTLLILVLGAIGLYYYIAKKQSRGRLPPGPKGLPIIGNLIDVPIEQEWETYAEWGRKWGGIFHISLMGQSMIIVNSVNVMDEFDRQGANYSDRPVLQMGGELVGFKNLLGLMQYGPIFRAYRKHFSRFVGSQKGIHLLHPIIEEETHKFLKRTSENSSAGKLIGNLRKLAGGIILQVTYGYKVKDGQDDFVNLIEKSNENLSTALTPGAFLVDVFPWLKYMPEGLPGTSFLKLAREWRKTTEATANLPYAYAESQMAAGTASASFVSTGLEDSEASYSPEYLHNLKWTAASLYAGGADTTVSTESAFFLAMVLYPEVQKKAQAEIDAVVGSDRLPTLADMPHLPYLNAIMTELLRWHTVAPLGIPHAAVEDGYINGYFIPKGAVIVANLWKMLHDPETYPEPFKFDPERHLGPTPQRNVREICFGFGRRICPGMLLAETSVYSCIIKSLAVFNIEKALDSDGIPITPVHQTANGLLCFPKPYECAIKPRSEKAYSLITEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJU5</accession>
    <name>A0A9P6JJU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJU5"/>
    <dbReference type="OrthoDB" id="2015213at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052896">
        <property type="entry name" value="GGT-like_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881:SF1">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="597" mass="64569" checksum="7B6D4A34C0ABB712" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKB1</accession>
    <name>A0A9P6JKB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_653610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKB1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040322577" description="CBM1 domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="4">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="8924" checksum="C618C8C041F82DC0" modified="2023-09-13" version="1">MWKPFFILAGAAAVVLADNPGLYEQCGGVGYHGSIRCEGDIALVCTYITPEFSLCLPDASSTTTRTPTADPTVTTRTPTATAKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKW8</accession>
    <name>A0A9P6JKW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_636025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKW8"/>
    <dbReference type="OrthoDB" id="2641874at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="110" mass="12669" checksum="8DFECD2D954D1BEA" modified="2023-09-13" version="1">MRQHTFIPKFTGSVVKIPLQPGRPRILNALNLASLESLIKRTADLSVRELQDELEEARGGVVSEWTITVTESLRSRGIYTETGNLSGTRMFERPTRFSWRKFTDQNSWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLJ0</accession>
    <name>A0A9P6JLJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLJ0"/>
    <dbReference type="OrthoDB" id="3029266at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="489" mass="56224" checksum="0880812A92F3A00F" modified="2023-09-13" version="1">MMEHWHHEFLVFTIIHEERELYLYFERELDENIEEWRGVVAFARALFRGEALDILWFHESGSEKDTETKKWAKAIFELELESSPDVEPFTLKHLARILGDGSYEEKYPKYGLFSANCWAWSRGFLFDITQHVDVTTKIRKTNGKEMVPITLEEMRLYMLTEYGAYGRLLLHFSSDDYDAQNRRKAFPESLEVYGIRIVLLLYTVLQSVVQLKSTIIGPSNWSVSLRTLCIYHDRTLEGSNNGLDCTFLPSKPNFNDFIPITPGHMDHPIPDSFCQPGRYLYLLSSPISTASYPVLSAHIHVFGAISDTTSDANSEPRMHDTSRWLSCGIIRRSEDDGDLIEVPESHIWLKVVLRDQIGRSAHQYKSISVLKVKNKFSAKIKHGDMIALWVHSYPEKLHQPRSASIKIVVLRRPLRMIDWILALLLLLEISRFVYKGSSYISLALSGIGCPLYWTNTFCEGWIWAKISALAIMNQESATPLSQSLPAPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLP6</accession>
    <name>A0A9P6JLP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component SEC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_859486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLP6"/>
    <dbReference type="OrthoDB" id="26242at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="53"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="950"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="975"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1008" mass="111710" checksum="FFE242B886E059FD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLY7</accession>
    <name>A0A9P6JLY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLY7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="9713" checksum="A2F6412C332EBABA" modified="2023-09-13" version="1">MARMSILTTTVTAIILFTSTMVVTSMPLLGRGLLGGGGGGGVLGGGGRVGQNAVGEIVDEVLGNNNGLTGNGEILGNGGVDDVLRGVLGNGGGAAPPLAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM26</accession>
    <name>A0A9P6JM26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_818688</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM26"/>
    <dbReference type="OrthoDB" id="514823at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="592"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="628"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="680" mass="74706" checksum="7B41087A5FCC8DAA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM91</accession>
    <name>A0A9P6JM91_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM91"/>
    <dbReference type="OrthoDB" id="2559662at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="477" mass="55251" checksum="2B2ADC336DA2C72C" modified="2023-09-13" version="1">MRGLVGRRPYLALGVVGFVLLSSLALLELREGGRLRRLSLSSTVSLEPAASCDPDPPANWDKLYKWEDELPQHNVDLPSPEGRAGRYVYFKNQIQMLGWNNQLNEVLLNTHLAYKSNRTYVFHDYVWKIDYYPWDHHPQRLDVPRTPVNALISGPSAGGPWGPGDNAPRAISLRFLDQVCPPEERRIINTRDVKPPIYWSPGDVVFNTWQKLLYEAPERCIEVQGATIEEDRFSQTFDLWFWGTTRALDVWEDFSKSPVSQLLRTSPIIQSAVDNNEYLFQPRAPRHLVPKGATNDAWDRTLAIHIRRGDYKEACMGLAQWNSTFYSWNLHTFLPDHFNHPPGWDVDRDLTVKTYLEHCYPDEDKIMEKIRKSRADYIAAAKPGEVRYLDTAFILTNDKSDFLERLKKRLREDEWYNVVTTRDLELTQHQKDVGMAVDMDMARKAAVFIGNGWSSFTSNIVHRRLIDGKEPISIRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMD2</accession>
    <name>A0A9P6JMD2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_517439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMD2"/>
    <dbReference type="OrthoDB" id="3022434at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="47799" checksum="914DB73E31B30139" modified="2023-09-13" version="1">MFNFFSSASQGPPSDAGSQSRPPSPRSPSTGSTANVDLPDEQNEEGPWLLPPEDQAGPSLHSSVERIMRRGSEIPLNSNPNGSRHTRSHSFSPPTQLDGPPKLRLDTGDSIDEKGKMKRRQQAVNPYMSPPLTNAPASESFLSGVERVSRILSRGLDLDIVEDDLEEAEELQSERSSTSSRSSILTERELRRTVKGKEREKSEKGKGKQRAVESITPAPHIIEVEEEEISAFDISSSSLTSHGESTTTRQATVGDTTLDDPGSIVPSVRFPAIFNQGDDEDEELDEEDELSTLESSPRSIILPVLPPQILLLRTPVDEEITQRRIMRHLIEPSSPVDEVTSAVEEKPSYKRGRTHYRPHPAYVGTRNGRPRYLRRKRWEKSQERGLSRDFFLIITLCFGLACAGILIIRPTAMALLGYNALANRLELDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMD5</accession>
    <name>A0A9P6JMD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase EFM4</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM4</name>
        <name evidence="7" type="ORF">CPB83DRAFT_859087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMD5"/>
    <dbReference type="OrthoDB" id="10069295at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="61"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="25107" checksum="373785257E4CEF75" modified="2023-09-13" version="1">MTVLELNPTKLGTKEHWDDVYDQELKSFEDLGEEGEVWFGEETVEKMVDWCIKNIPPAPSQKILEVGCGNGTLILGLLEAGYSAETLHGIDYSEGAVNLARAVAAARKGSGITYTRRDFLKDDSLHPNDSAASWDLLLDKGTLDAIALAQKDEKGRSLISYYPAQVARLLKTGGIFLITSCNFTEEELKEIFTSDRLDYLSRIKHPAYTFGGKSGSAYASVAFRRTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF3</accession>
    <name>A0A9P6JMF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF1692-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_795758</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF3"/>
    <dbReference type="OrthoDB" id="5541786at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF81">
        <property type="entry name" value="ER-DERIVED VESICLES PROTEIN ERV41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="169"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="548" mass="58616" checksum="BFB2B64B5518FC2F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN03</accession>
    <name>A0A9P6JN03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_816450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN03"/>
    <dbReference type="OrthoDB" id="3251271at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="36852" checksum="3413D010F8621238" modified="2023-09-13" version="1">MSKTISTGTLSLRFMQNAQRAKQLKEVELERAEVQDDGKWEVSQAIKDAWGLKEGEPSSSSQTIDVHEASYLPFIFTASGKGDADTSADANEVARQRLPGRRVFNKRGEEVPLNSSEADAESLPKTVIPESSPQPGGRKIHPRPVTISATASGSRGALLKGFDTFEQTRIFAPKTDYYKGNARSEDTKAKSARQAVFETTDVGVDLRVGQTKPKPPPLEAPSSSATFMKPPGVDVPKEMISGLTKGRISTKPKSRAQEIIEGARAKQNNKQEGVTTSEFLKPKGVDDAPSLSIDISLNDTIQQASNETKKKKRSKRERDDLQVDKTPSRKKKKTEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNH7</accession>
    <name>A0A9P6JNH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_816709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNH7"/>
    <dbReference type="OrthoDB" id="3217871at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="44"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="335" mass="38545" checksum="619BE5CC50B500D7" modified="2023-09-13" version="1">MALAQVVSPTFMSRPIKRSRSETIDLVAEKQETVSSRNFWFDDGNVVLRAEQTLFRVHGALLARHSKIFKEMFTVAQPDNSLETTLQSTPVFSLSDTVVDLEQLLFIFYDNVKALDKSDMTYDMAAAMLRLGKKYQIDYLYEEAKIAFRKDYPTSLDDWNPTIAVIPNARRGDMINLAHEISLKTVLPSLYLDFISAYSLSEIIHSGKTIDEPRFTLSIRETMIVGRDRLILYLQEQRVLHLKWIGRNRSYVGCRNPLHCNDYRMGFFESISLWKLNDGSPCNLGPWVERKHSSLCSSCNNQMQEIFNATRAAAWAKLPSFFGLDEWDKLEDEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNH8</accession>
    <name>A0A9P6JNH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNH8"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="100"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="428" mass="49458" checksum="E81573978459B006" modified="2023-09-13" version="1">MGGASVKKSASSYFSNGPEYEARLKKPFVPPNIVLKDIHDAVPKHLLHKNPTKASLYILRDISFTVLLYKFASSITPWAASDFWGYVHTPWQKVFLKSAMWLSYWWIQGIVNAGIFCLGHDAGHGSLFESKLVSNTVGFILHTYILVPYFSWRSTHHAHHKATGSMERDENYVPYTRGKYQLPDEKTATRTDYLEAFEETPIYSLTRIFIMQTLGWWLYLGNNAMGSPKDLAGTNHFNPYSTLFKPHERNSVILTNLGLAAWAYGLYQIGGEFFMWYYLVPWILVNHWIVMFTFLHHTDPTIPHYRKPAWNFVRGAIGTVDRPLLGWMGRFFFHNISHDHVAHHFFLRAPFYNGPEITKALKKVLKDHYNYDSTPTFYALYRSFNECVFVEDQGDIIFYKNKNGIAARDLGAVEQPVQDVEEVSDKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNP1</accession>
    <name>A0A9P6JNP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_856388</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNP1"/>
    <dbReference type="OrthoDB" id="409586at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="109"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="205"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="32250" checksum="7C85CDE6D862094A" modified="2023-09-13" version="1">MSNQAVKDLTAGTAGGIAQVLVGQPFDIVKVRMQTAPKGTYSGMLHCAGGILRNEGPLAFYKGTLTPLLGIGVCVSIQFGALEYAKRIFADQNLKAGRGGEGGRTLTGSQLFTSGIFAGLANGVVSGPVEHIRIRLQTQSHTNPLYRGPWDAIKKIYSHSGIAGIYKGQAVTLLREASGYGIYFLTYEKLVQREMAKKNIRRDQINPANAVLYGATAGYALWAIIYPIDMIKSRMQTDGFSPGSGQKYKSTLDCVRTVWRTEGIGAFTRGLGPTLIRSPFANGATFLGFEMAMRVLDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP55</accession>
    <name>A0A9P6JP55_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_768458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP55"/>
    <dbReference type="OrthoDB" id="3231772at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="17294" checksum="31FDB7A8C4008EE5" modified="2023-09-13" version="1">MASVHVLPVPIESTFEKRLLPVAQSEGHFAFARIQGELHLVQVSDATPASALTTVDVKLFRHEFITIFRFAGCRTLHPADINIIEPIETNLTRYEEDNGTVFLARDVMDRMRKLTDPRRNLGMGMIPGRVWKDARQPQYRLKTVHRHHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPN7</accession>
    <name>A0A9P6JPN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_369126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPN7"/>
    <dbReference type="OrthoDB" id="3045590at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58867" checksum="4A1A410227FC4595" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPW4</accession>
    <name>A0A9P6JPW4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPW4"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040224959" evidence="1">
        <location>
            <begin position="24"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="39"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="317" mass="34095" checksum="8F7C963870D436B5" modified="2023-09-13" version="1">MFTRSWGYLVGLSLLATCNLVSAYSLSDTIIGSNFFDAFAWEAIADPTHGRVNYVDQGTARNQNLSYASGDTFVLRADYRSYLGSGGAGRNSVRIRSWKAYTNHVAVFNVRHMPQGCGTWPAIWEVKGSNWPDGGEIDIVEGVNDQSPNAATLHTSGGCSMPGSRDETGSPTQLDCNAAVNGNSGCGVKFRNSNSYGPSFNSNGGGWYALERTSSSIKVWFWARNDGGVPAEVRNGGSNVTPGNWGTPSANFPNSQCNIASHFQEHNIVINLTFCGDWAGGVYGNSGCPSSCDDYVNNNPGAFQNAYFDFASIRVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQU3</accession>
    <name>A0A9P6JQU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GRF-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_852852</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQU3"/>
    <dbReference type="OrthoDB" id="5418639at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="7">
        <location>
            <begin position="11"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="28011" checksum="9E855B19E5711DD5" modified="2023-09-13" version="1">MATFTPKIIKCQHGLQCTHFVSHKQGGRIFYRCPLPISDKERCSIFKWDDELSEAENRGSDQHIPPTTSSALPNLPSTPVQGQKRSFNQSFTDDHAQSPSSHKRTRLMEAALKRETEDTLLPMRPQTPLRRLGQRLSFNAGSQPRTPFRASNAEPGPSKHQDDDAPGGSQYTLAGDEAQELDADSVRDLLTKLSDLPDYIIKLERKKLAAERSRDIKAKKIADLEQENANLRIRLEELEELVAILEAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQU4</accession>
    <name>A0A9P6JQU4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_812907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQU4"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="4"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="230" mass="28110" checksum="BD241448154B63D9" modified="2023-09-13" version="1">MPPRILFVSGFHPTTRARDLAFEFEKYGPLVRCDVPAPRNPNATHNPYAFVEFRNGRDAEEAYHEMHGRSFEGNRLGIQWAKNPPSSVWRYERERDKDRDRDRRSPPPVRRSRSPRRRDDRDRRDDRDRRDDRDRRDDRDRVRRDDRERSRSPRRRDERDRRDDRDRERRRTPSPLPERRRDDRDRGLDRERDRARTPPPMPHDGMNGYGKERDRDGRDRAHTPPGPYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQV8</accession>
    <name>A0A9P6JQV8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_273503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQV8"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="813" mass="88925" checksum="0B9A1AE6FF575EC9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRY7</accession>
    <name>A0A9P6JRY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRY7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="84" mass="9417" checksum="9CEE023D0F0E08C8" modified="2023-09-13" version="1" fragment="single">MVSWFTPILSCMIWIVPGIIQLIAVKYVKEQPTSIVPSMIVLLNTSSSGSQPPAFFRSFALLYSAMFMNLADLYFTSSSTFLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS99</accession>
    <name>A0A9P6JS99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_833399</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS99"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09533">
        <property type="entry name" value="SAM_Ste50-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46829">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46829:SF1">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="6">
        <location>
            <begin position="12"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="7">
        <location>
            <begin position="249"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="476"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="584"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="159"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="692" mass="75220" checksum="1F733BA22B01711B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT20</accession>
    <name>A0A9P6JT20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Origin recognition complex subunit 5 C-terminus-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_849129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT20"/>
    <dbReference type="OrthoDB" id="365981at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048866">
        <property type="entry name" value="ORC5_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21639">
        <property type="entry name" value="ORC5_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC5 lid" evidence="6">
        <location>
            <begin position="256"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="5">
        <location>
            <begin position="397"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="560" mass="62693" checksum="0B549C538A81D5F6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT65</accession>
    <name>A0A9P6JT65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 76 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_904266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT65"/>
    <dbReference type="OrthoDB" id="9984024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040335038" evidence="1">
        <location>
            <begin position="23"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="41006" checksum="7F9796E5A0D3E874" modified="2023-09-13" version="1">MRPTSWKALTVLASLVAPFTQAQQCGMILDTAKSVTNRLQSHYYSSASGQYNGGSLWTDANTIEDIHNLMLATGTNEWSTLADNSYIGRSALNANTNWNAILNGSNDDAGWIILALWKVADYKSSRGQDNSAYMRAAQSIYDIIKNQWDGTCGGGLWWSSAHTYKNAITNELFLFVSAAGYIRTKKQEFLDNAKKTSSWLLNSGMRNADGLWNDGLDLNGCRNNGQTTWTYNQGVIASGLAALYSITGDKSLLDQAEITLDATIRRLSNNNILRESCDNTASGQGSCNQDQQIFKGIWTKHLQFYLDNANDPARTAKYAGFLHSQYSAVLHYGTNGDGDIGSVWYGPNQGGSVFSPKTSSSGLAAHVAAAKYGTCAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTJ9</accession>
    <name>A0A9P6JTJ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deoxyhypusine hydroxylase</fullName>
            <shortName evidence="9">DOHH</shortName>
            <ecNumber evidence="9">1.14.99.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Deoxyhypusine dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Deoxyhypusine monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LIA1</name>
        <name evidence="11" type="ORF">CPB83DRAFT_846083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:14101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="Rhea" id="RHEA-COMP:12592"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="ChEBI" id="CHEBI:91175"/>
            <dbReference type="EC" id="1.14.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the deoxyhypusine hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.29" evidence="9"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTJ9"/>
    <dbReference type="OrthoDB" id="421002at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019135">
        <property type="term" value="F:deoxyhypusine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000099">
        <property type="entry name" value="Deoxyhypusine hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03101">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027517">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03130">
        <property type="entry name" value="HEAT_PBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="141"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="331" mass="36272" checksum="1927BF3700F1DF2F" modified="2023-09-13" version="1">MSTIQVSPDKLKSLEECLCNFKGNVALHTRFRALFTLKALKSDEAVGIISKAFSDPSALLKHELAYCLGQTKKISALPTLESVLRNTAEDPMVRHEAAEAMGAISDPSSVSILREYLTDSNRSVRETCEIAIAKIEWDNSEESKKMQGSSSESQRFTSVDPAPATSSLLRRPPSSSSSLSTESISALQSQLLDTSLPLFKRYRAMFSLRNIGTPEAIDALSSGFADSSELFKHEIAFIFGQLVSPHSVPALLKVLQDTQESDMVRHEAAEALGGIATPEVLPHLREWMNKEDAPSVVRESCQVALDMWEYENSNEFQYANGLGSTIPITVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUD7</accession>
    <name>A0A9P6JUD7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_759759</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUD7"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000657">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="214"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="410"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="43"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9532415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="620" mass="70118" checksum="943567941BDA193F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV65</accession>
    <name>A0A9P6JV65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV65"/>
    <dbReference type="OrthoDB" id="3269047at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="567" mass="60412" checksum="D4988C7D9BE61599" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVM3</accession>
    <name>A0A9P6JVM3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_865819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVM3"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040529504" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="32"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9535607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="60027" checksum="3E897778E247A522" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVM5</accession>
    <name>A0A9P6JVM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_832063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVM5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040264197" evidence="2">
        <location>
            <begin position="24"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="647"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="691" mass="67832" checksum="CCBD55FBA6B8A715" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVP1</accession>
    <name>A0A9P6JVP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_322342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fl(2)d family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVP1"/>
    <dbReference type="OrthoDB" id="3363802at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033757">
        <property type="entry name" value="WTAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17098">
        <property type="entry name" value="Wtap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="347"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="446"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="471" mass="51060" checksum="81745D95BC262ECA" modified="2023-09-13" version="1">MELPSARELELEVLLRERESQLAELKDEVISLRQYLSKQPGLSASESVSLPPPLASVLLPHINAAASNTVTNVSATVTGGLNQRMRQLQEENDELYNLLKSSETGKLKDEVRSLRRAVSKLEGALKESHSVISSLSDELEKTHDALMNSSRHKEHAQGNTRPHSPRQSYQGEHEPARSHSHRPGRGNRDNRDGRDQDNANVSTTSSSSNRPPPTGPRANKRPRLSEPQASASPTPTRTLAPLPPKPPAHNHNHPQHSLHAHQVPHNHHAHGRNHNGPLAPMRENSRQPTNTTGSAPPSGSGANGSSGGTGTTGDKESRSHNKLSANLPPKMEVDDSTDALRAPSPAPHRERERDRDRTRDRDRERERNNKERERANRERERGSREGASSTPAPSNPSIANSGGIPSKPPPSNSSSNSRRNGSSYPNSGGREGRGDRGGGGGGMARKGGNSNSNNSRSNQSDNLTLSQRMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVS9</accession>
    <name>A0A9P6JVS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_35497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVS9"/>
    <dbReference type="OrthoDB" id="2637024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="16096" checksum="1C830BB0B5FDEB6E" modified="2023-09-13" version="1">MSLQVVQIDPADALFTPTSLEHLPNYEEATGQAPRRKSPNGRLPPFKRCRSARYHPYKRFLVDTADEIDSFIDTIFDPEQQALDVPPALPDRQRAYPLLLDYETMIDQRIRIILMAERAQQLDDALIANDFLASFTGTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWS1</accession>
    <name>A0A9P6JWS1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-lysine N-methyltransferase EFM6</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Elongation factor methyltransferase 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">EFM6</name>
        <name evidence="2" type="ORF">CPB83DRAFT_755564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWS1"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03198">
        <property type="entry name" value="Methyltr_EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033684">
        <property type="entry name" value="EFM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="103"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="27268" checksum="5A67420C9FC9C65E" modified="2023-09-13" version="1">MQQQDDELEGIIAPEGLARASASASELLNVLPQQSHSVESGGRLKLSFSHEWRDVINPLEISLVVDAAPGCGGLAWPAGQILASYLVQKGPEYIQSKCILELGSGTGLVGLVIGAIQNMDIWITDQAPLLDIMNRNVRLNNLETIVKVAELNWGATIPAHIPRPDMILAADCVYFEPAFPLLVQTLSDLSDAKTEILFCYKKRRKADKRFFGMLKKKFTWKEVDDDPHREIYNREAITLVWLSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBE0</accession>
    <name>A0A9P6BBE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158134">
        <property type="protein sequence ID" value="KAF9521314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBE0"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="501" mass="57083" checksum="2B16B47FDE930A6A" modified="2023-09-13" version="1" fragment="single">MGITQSKRLRLRKSKTVAVSLHPDLLLEPDRHPMAAFSRFYKGANNSGDSFQSGITRNRSISSINSMTDSSGSRSYRSRSQSPSPYGHPPPVMVIPQSSPPLSWQGGSQHGSAMEIVPEDITYHPQDLKGILEGVRFDISSSPSFNRLFQFGDALQALLDTALFTGEDLRLLDTDSNVDNTIPNSDPKEPRIGHIEKQEREKIVIGILDLMFLMTQTYTQDYDSHAIAESLLQRIKLERTRLFGTGDAMVSSATGGLAVLYYEQRRWAEAEVTAAEFVGEDRGTLEKWDSKILFFFAKLYIRQGKWVEVEPVLEELDSRTGLPEVIGQAGCLESLLDAYIAQEKWSKVRELAEKHEYLKDRRRMDRIMALIGQENWVEAKRAIRRDREVVYYIGSRPIAYPVGQRRREPRSHHMLALIYLGQQRWERAESKFSGGIGWDRWQRAIRKSNWRHDDWRNLRGARGLCEAYMGMNKDGEAERLLLQVIEGSKSALGDEDVDTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2U9</accession>
    <name>A0A9P6E2U9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_841257</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="MU158060">
        <property type="protein sequence ID" value="KAF9521455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2U9"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF26">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP16-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="176"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9521455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="276" mass="29520" checksum="CF7424B2F2BD37BE" modified="2023-09-13" version="1">MSNRLWGRSTLRLDYKASGNETNSTPEEKLSIICTLLAGVIEQTTLSIPIFREDEAVFSVLGKNDMYLTGILFRRRDVDLEVSCAPATKALDTQIPLKKPNGLVIATPQGHNVNGTAFKGMATAIASSSKSSGSAAFGGVSNGFGDHPLSTSTPKAQASFKYKNIVKGTGDPATNGSKVTVRYTLRGQVQPQPLLSTSGDTPVVMTVGETSLVPGLAAVLPGMLVGGKRQLLVPCQSVSQRQWQNLPKSTPLSDLLLDRKDSCRQQLEEPSEILIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2V1</accession>
    <name>A0A9P6E2V1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_736444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158045">
        <property type="protein sequence ID" value="KAF9521485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2V1"/>
    <dbReference type="OrthoDB" id="3067228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="57" mass="6382" checksum="1111791AF13983CA" modified="2023-09-13" version="1" fragment="single">LSHSLVKVGLFPISPSQTRTAITIECLNFYSALFERSWDEVTAMAAMTNSVYSHRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E366</accession>
    <name>A0A9P6E366_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158005">
        <property type="protein sequence ID" value="KAF9521666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E366"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="428" mass="48095" checksum="A43E818EFBFFEEA4" modified="2023-09-13" version="1">MVAVLSRRVFLQTDSFFVARVRLFGKLEINNEDILKITKLRELLEFDGGTIGMPSLSCCINFFKMGWPPYSFDPRNFGGSRQGSNSSISGYALDETAEFHQVQVGPQNHRDILQAICGIISSPSLESLTLENFWYIPYDAFDIRWIRSLKLTNVTFSEKSIKSSSRPTSDSAFGKTIKPRIVEQSQLRTFHYVFRPPLPSHWLASPLISPFSRLHTLTVEFDFMLPETPTSAFDSLLKISSATLHTLNIDLKDVKARDSPAKPVFECFPHLLQQLTGLHVLRFTVPTTMCFHLGWGGDLAKLPVSGSPMTVKNWFGQIIDVVDSLRTLKSGKLPQTLELMEVQFLVLCGTVDDVGLKEESDWTNVGDILMSIAEQLIIGGSKAPMVRAALYVQVNFAAQSENLEVLAPLVLDFPNFVKTSTRKLRLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3J1</accession>
    <name>A0A9P6E3J1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157978">
        <property type="protein sequence ID" value="KAF9521876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3J1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="38786" checksum="427F2C8100DE8257" modified="2023-09-13" version="1">MLPSEEFETTSVRAKATRATVYLPAVDDSSFLSKKNFANRVVFPIFQSEVSLVAGGPCPADLEKRIRLHNFGLLDDALCSELSVWVELAGISRSFARASISGNAHQPMIKALHQQVLSSKDNDLTEFVLAQAGTFIFQLLRAPETGLGTMQVFAKLVEKSTFGELLTRALVRFTASPNPSTDAAQIWLAILGLVINTAECYIKFGSYLEATPTELHDIRTFVELMHFQTRKGLAADLERNASASQKCLDKWEKLVDVVGSNVQTIRERYKLQPSLRVLDARQFTTVTSHDKSYWATHKPNCDPTMFACVGPLQSLYDTLEENDLWVLIYRLESYRVIIQILLQTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3T9</accession>
    <name>A0A9P6E3T9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_727222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157968">
        <property type="protein sequence ID" value="KAF9521992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3T9"/>
    <dbReference type="OrthoDB" id="3270336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="125" mass="14133" checksum="7BACA1B6D8BE7E71" modified="2023-09-13" version="1" fragment="single">RPAKYTFTKSDYVAYRKQCQAILQHPCGRAALMDGGYYWRLAMGLVKWEDVLKGPSGLSLNMDEMVVIDDKVHGLLIDDRLTVKEANALCGTYKVPTEKGNQVASQSWFMPVNVYKNCAIDLGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4T6</accession>
    <name>A0A9P6E4T6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_112809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4T6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="121" mass="13627" checksum="BDBF675A2014C23A" modified="2023-09-13" version="1">MTKGFGSDAFETPSQLGPCCHVSVTRFHDLWPVRAVSLYAPPTRQRIYLSPSSLLKSRALVAFLGVMIGGTICCASWLLENRIKVEIKALYIVDFLITTTCRKVWIDHFSATSFRGCWRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5C9</accession>
    <name>A0A9P6E5C9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_74862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5C9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="420" mass="46928" checksum="0A8AB2F8A58EA6FE" modified="2023-09-13" version="1">MMENFRASPVYIGLGRRSLLNRIDERDDHDQRSPQMPFPKAHSMAYRRSKKRVTLPPVCQLIAESDAILARSSGPLPQVKITMPVYRPNFDAGFKKETQVPKLHVRERTAPYPSQRPLEPSLSRLTRRQVAVSRDNRTSDGERSRRSRKRELQRERNYLHSGFPAMSPPELLATLARAFPLSNDLSQTLRPSVSHENGDFQPSGKLCEYESIEVTHLTYRRCNAPTCFFVPRVEIGGVIDQSCKLEVGEGVSKAGNIITFQFCPSTGSVEAGVPLLQIEGDPDRIVGGWDDISKLLSPCPGARASDSEKTRHASDACEEGVKIIVGFDGHTLTKVSREVQLRCLCTGITRARIAYEVLQAFRCYLAVTMPTISIVHSPSSPSMPMKTCDPHRGALQQLRLMSIFSPDGFHWVPNFIVSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5G3</accession>
    <name>A0A9P6E5G3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ornithine decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_74288</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-ornithine + H(+) = putrescine + CO2</text>
            <dbReference type="Rhea" id="RHEA:22964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="4.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Only the dimer is catalytically active, as the active sites are constructed of residues from both monomers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.17" evidence="6"/>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5G3"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00622">
        <property type="entry name" value="PLPDE_III_ODC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000005">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="10">
        <location>
            <begin position="110"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9522835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="505" mass="55034" checksum="8A8B1C10553164CF" modified="2023-09-13" version="1">MSRVATLPAVNPIDFTLSSSPNSRPHLRDSNLSWTSSAFIHEAPIASPTSLRTTLKTINDVEEDIIFPSLPPLLSGHPEVHLRNGIMNASRLASANTPDAEKAFFVADLGQVYLQHQRWKTALPEIRPFYAVKCNPDPYVIRLLAALGTGFDCASNNEIAQVLEVGGIEPQDIIYANPCKAASFIRNAAKVGVDTMTFDNSDELYKIARVHPRARCVVRILTDDSKSLCAFGVKYGAPLSTVPGLLAKAKELGLEVVGVSFHVGSGCYDPNVYMDALMRAHSVFVMGNETGYNFKLLDVGGGFEDALFEKAAAVLKAGLDRYFPNRQDMQIIAEPGRFYVSTAFRLATNIIARRAPLKPSTPSLPSATAPDDSAPNVDQPVVMYYINDGVYGAFNCILFDHQIVHPHVLSMNGSFHVSQDEPMHLCSVWGPTCDSIDCVSKKTTLPANLHVGDWLGFDNMGAYTICAASQFNGFELSKVIYTTGGSTRFEVRNILAAFAAKFSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E608</accession>
    <name>A0A9P6E608_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_863372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E608"/>
    <dbReference type="OrthoDB" id="3265526at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="82"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="229" mass="24595" checksum="25AFE8A43E7A169A" modified="2023-09-13" version="1">MMLIGDPLIMSVLSTSTRLFVTWRMKCISSSVLIPAILGFVTATALAGGISFAANLASASNPDRIAPQVTNALKVVWLSATALADLIVAVTLSLSLRTRQPGAKIIKDRFAKFLRHSVHTGLVAAAISSSNLIVALALPHTTINFVWDVVLSKVYVISLLSILNTRTTAHNGTVTEENVLFGNHDGGSMTSSPSRKRPAEVYELGRLENSIAITTVVEQMKDPSLWNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E617</accession>
    <name>A0A9P6E617_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_776084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E617"/>
    <dbReference type="OrthoDB" id="3247158at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053242">
        <property type="entry name" value="PAM2-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46651">
        <property type="entry name" value="POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46651:SF1">
        <property type="entry name" value="SMALL MUTS RELATED FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="511"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Smr" evidence="7">
        <location>
            <begin position="814"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="511"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="253"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="900" mass="95874" checksum="FDF9C6062BE90926" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6A1</accession>
    <name>A0A9P6E6A1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_886993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6A1"/>
    <dbReference type="OrthoDB" id="409948at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE/SOLUTE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567:SF1">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="189"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="373" mass="40935" checksum="A0F6BDA0826821DD" modified="2023-09-13" version="1">MSAERLKTTTATSTDERQPLLQSTEDSNHAVVDMTSEGEVHRREFGEPETGKVEHLTWNWVAFYVVLFIGGLVALGLLIKGFIDAGDKDFDLAGALKMALGGGLSGAAAMVLQVLTLMPLRTIMNYQYRFGTSLSQATLTLYNDGGWTRYYHGLTAALFQGPLSRFGDTAANAGILALLESNAYMKTLPTLIKTVFASLAAAAFRIILTPIDTVKTTLQTQGKPGLRILKARIARYGIRTLWYGALATAAATFVGHYPWFGTYNYLEAHLPEAHSTLQNLSRRAFIGFVASIASDTISNSLRVVKTYRQVNETKIGYMAAARAVISVDGLRGLFGRGLKTRILANGLQGVMFSILWKFFLDLWNEKTKNEIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7J9</accession>
    <name>A0A9P6E7J9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_774565</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7J9"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000193">
        <property type="entry name" value="Zinc finger protein 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="110"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="18111" checksum="EF210FC142FB2DC9" modified="2023-09-13" version="1">MGPDPLPRPWHTPQPSDAHDLLERAPTGRYGPTTGQREPHTSTSHTHQMQEESGGSIAKYECQYCGKGFNRPSSLRIHLNSHTGEKPFICPVESCGRSFSVLSNMRRHARVHMGPSPGPINDDGSGPSFEEGSSSLEHGQRRSSNASENSQRSQSPSSDDFEDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8N5</accession>
    <name>A0A9P6E8N5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8N5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="216" mass="24709" checksum="1FA135F611AA76E1" modified="2023-09-13" version="1">MDCPLTSSALNKPLILDFKQLIYLLQAETLKATDELLRVLKITLIKNLNGFRREWLLVQVIEPASRTVMYFRMERGLWPVTDTITRTDGKLNQSDVVMEELKFVGDLDSEENPRLADIAALATASEDLGIIYTLSPYHCYRFAGLVFGACATLPFKHVFLVHETRLKAGYFGWMSLVEIKEGEKRALARQFRPSHEARCPTAKKPSPKRSYQLRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E975</accession>
    <name>A0A9P6E975_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_945505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E975"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="133" mass="15078" checksum="29DF7F8C883B20AB" modified="2023-09-13" version="1">MDIADKAAALTLRMSASEFLKRARESNLHDSVVVKWYRFREQWSDIFTEHILSKPRMGMLHKGGAKTCELWGPFQFEVIKRIAGDLASINRATSIIEAEDDIIEGCNYCKDKASRWGRSIASAIGNIEPFSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9R4</accession>
    <name>A0A9P6E9R4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_860248</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9R4"/>
    <dbReference type="OrthoDB" id="9992197at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR619342-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9525075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8954" checksum="CF3C7CBCCB4A251E" modified="2023-09-13" version="1">MSSGFGWTGGRPRCFVYWQEFQKCYIQTDNPVECRPQSGDYLECLHHTKEIKRAEAVKDEMQRQLEHEKAKKHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Z7</accession>
    <name>A0A9P6E9Z7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Z7"/>
    <dbReference type="OrthoDB" id="2978551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="687" mass="78266" checksum="57A817115A279072" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA86</accession>
    <name>A0A9P6EA86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_859678</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA86"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="117"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9525344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="38726" checksum="8C9D6606003AD1F1" modified="2023-09-13" version="1">MALILPARTHPEVIVYAVGARNLDKAKKYAKKHRIEKAYGSYQELLDDKDVDVVYNPLPNALHHEWTMKALAAGKHVLNEKPSANTAEDTASMFDLAEQKGLVMMDAYHYRFHPAVLRVKEIIESKTIGKLKTVTAKLIVPKGITAEGDIRYDFALGGGALMDMGVYTVNCIQYMTSSRSVEVTDATTELYAPKNKPESYASNIDRTATATLTLSDGIKGNLEVDLARPLRYGLIPTLDMSFKAEGVLGSVEIDNYVMPTLYHNITVNIRGGPISTEKVYKNRFGEREEWRTTYMYQLESFVDKVRGREPKAWVSKEDSVATMKCVEKIYQKNGLGSRPKSAYIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAR2</accession>
    <name>A0A9P6EAR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_885409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAR2"/>
    <dbReference type="OrthoDB" id="10068793at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02231">
        <property type="entry name" value="mucoidy inhibitor MuiA family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005:SF8">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4140" evidence="2">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="1">
        <location>
            <begin position="193"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="610" mass="66914" checksum="A0AD2E3790EE88F5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB48</accession>
    <name>A0A9P6EB48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB48"/>
    <dbReference type="OrthoDB" id="2919059at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040278942" evidence="2">
        <location>
            <begin position="34"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="848" mass="94737" checksum="AC8B1CB45C79F8D8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBQ6</accession>
    <name>A0A9P6EBQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBQ6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="437" mass="48739" checksum="E96F82FE7FFA3823" modified="2023-09-13" version="1">MDTNRITLPLEMQELVITALYSSVYTHPSEMLLDGTGDFRSLNGCTFVSRAFLRICRRLRFASLQINQAPDIPSQTSSKFVQVLEDPPKNLLEGIPSIGSYVRSLNLSITGSDVTHYQEELSEALHKIPQLQSLALSYVGMDHTTIDWDVFQFQALGDAILSLLRLSTFRTLVLGKYMTKFPVSALRGTSVKALMVQGTSFSCHKVSDSELSDTEEGEEEEKEEETKEGAPPHLEELHAISLCGHGITSLIFPKEDPWLDITRLKTLTMTLQASPDSEAAAQQVFSCMKSPHRLNLVCQSKTFKGLFDNISSCLDTLSELRLTVSTNPFPLPTTYCLEEQLSYLNAELRSLRDAPVNNIKNILLTFINLTFDDAEALRTSKEWETLDQSLVPSEDRGSWGSLKGVFFLAVGCGVKAEDFKKLSSCEQIIFQMHCGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECD8</accession>
    <name>A0A9P6ECD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_442915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECD8"/>
    <dbReference type="OrthoDB" id="3062174at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040308372" evidence="1">
        <location>
            <begin position="33"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="163" mass="17435" checksum="01BDE3DB22332AB2" modified="2023-09-13" version="1">MKQRKQRTNSGALSLTKLAIVLLGASPSPAVAQSQSDTALDTLKGKNGESACTLKENIYKGCNIDPSTNSPDRPASCTCNLEFFNIMSACAYTSFSSSSAPTLPVYSDWITTCSNSGINMDQAQLLSNSDTWGVESPDWARLGVPGNKTIDLQRAVLCELFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECJ8</accession>
    <name>A0A9P6ECJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HORMA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_895593</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECJ8"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007130">
        <property type="term" value="P:synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="8">
        <location>
            <begin position="16"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="400"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="701"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="415"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="751" mass="84797" checksum="30A27ADA33A86CD7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECT7</accession>
    <name>A0A9P6ECT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECT7"/>
    <dbReference type="OrthoDB" id="2912435at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="527" mass="60404" checksum="4DDFF0129B443348" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECX7</accession>
    <name>A0A9P6ECX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_452462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECX7"/>
    <dbReference type="OrthoDB" id="3357439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="492" mass="53869" checksum="1B2B5419C11AA7F3" modified="2023-09-13" version="1">METAKKRKRDDEVDPPRITYDAATRTFDRLFKEESLGEMKNVVRKKLGVSTAVPVYLSQIRDGKSVDLDDDEDFEAFRAATRSLTIAKIKVVLGGHPTNGQLVNGSAIEPKTPKRKKKKQRISDAIASTSSVLSERPFGEPPATNEESISTPHKKRRVSFLEPPTLEQISTQSLLPETPKKKKTKPTGDPLPKSAIANEADVQFIQQLPETDTDEQAPRTKKKKKNLDQPKGDISGLQQDEVSSTISQVTDTASAQADESTSKKSKKKRRREDPEPNVITEPEDNASTSAVQAAKQLAQEEDTTRPAKKSKKQNADPTDEVTTKKSSRSKSVPPPAVEPPAAAAPVLDDEEPEAPSTKAKKTKKKKDREVSEPPTKEVATKPAHLEEQEDEAVVPPKKKSKFKQKDVTVLDETNPDTSKPTASLNKSLEKEKLAEVSSASAIEPSGSLNDDQPPEKAQKSSKKDRSRSKAPEEDVQPEDVEPTTVDGISSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED51</accession>
    <name>A0A9P6ED51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED51"/>
    <dbReference type="OrthoDB" id="3227921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45528" checksum="A1D7F3CB50C905D0" modified="2023-09-13" version="1">MKILEEKRLFGCLWQRHNISWQIDLQAKQPQSQGSISGVRVLLGDWRRHLPGEGDWVIFTRGLISVVLIFAVICFGLFAIIIQPLQDSGDIGVKEFRNVWEPAFSFDADVVNATVILFQSRGSGFLNLNDAASVEMIDGDSARQACKRPRPAVFACLDKGWADILVTINDTRKLRSPVKVFIGYGPTEAILVNSPGITLKPGISLLGEVKPVVHRILNSKRLSVRDIFDPYVTTMATEILYLWPDPQQVKIMQDYRDEPIFDGVASLGGFATFLAGIFSAVFGTSIFKILFGIKPLSVYGLAHWLSGPKLRHACIAEYPRIAQDLQNTPEGRGLLSFIHDHLLDMDLSKLTKKSKVASPSDIETSTNTPVIPLEVLGRESRQSMYSELWTEETMLLQTENVSIQVHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDR9</accession>
    <name>A0A9P6EDR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_876384</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDR9"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="13">
        <location>
            <begin position="189"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="14">
        <location>
            <begin position="514"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="15">
        <location>
            <begin position="618"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9527573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="720" mass="81208" checksum="60B30F8F3F2C8BA4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDU3</accession>
    <name>A0A9P6EDU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDU3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="11800" checksum="15E80E05E6E96C62" modified="2023-09-13" version="1">MALNIQKGGGLQLSIFEHRVLFSNHFSNPNPKYTCTCPCQRKLPTNISSSLPRTLYYVGSRYPHVPPFFSSQQFMIPVLYIFFSSYFVLLKFLNSLRLSPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDV7</accession>
    <name>A0A9P6EDV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_856601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDV7"/>
    <dbReference type="OrthoDB" id="497380at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="86"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="357"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="671" mass="75319" checksum="A0481F8FBE800668" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE09</accession>
    <name>A0A9P6EE09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_836832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE09"/>
    <dbReference type="OrthoDB" id="2831360at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="144"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22814" checksum="68BABA0CD2CA11FA" modified="2023-09-13" version="1">MSELILNVFTYGPNEKRVEIEMQPTIPENLRGNIPKMQEWAKNLIMVSCWDMKHTNNWLCEICSKLSRETKVQMASRIHFAQPRITLYIHHLCEAGTNPCHQIIVNQGVMMGAVARGGIPDRGLTEDQYIPKPDGVEYPLAASCCGCKDDNTAKRGVKMSRCGGCKLSRYYSTKCQSDDWKRHKKICKYVKSVKWVNWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE55</accession>
    <name>A0A9P6EE55_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_836689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE55"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="276" mass="30768" checksum="776691AE3909C030" modified="2023-09-13" version="1">MDNRDPRQYSYETQQAYPSGHVAAHNVDYVAIDGYTYDGPTQYYTPPNPSLSSGSDESNPASPYFRNTTTSMVSPHRYQNTNREVRYPSPANYVGNPSPSQTVYSSTQTPPYPSQYLPMPDQNVPQSLHHPPQQTRFIPTPSQIANSYSNYAQQVVDPSGHHDLYGSSSLDYSSNSHLIPSSAGRPARISTARPRGSSSNSNSNSPVSATSSPSGERFPCEKCGKTFSRSHDRKRHYETQHLPSPVIHRCGYCHKEFSRADSLKRHLDNGCDEMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEG5</accession>
    <name>A0A9P6EEG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_855178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEG5"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052443">
        <property type="entry name" value="E3_ubiq-ligase_RNF220-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031824">
        <property type="entry name" value="RNF220_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13459">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13459:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15926">
        <property type="entry name" value="RNF220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="389"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="441" mass="48506" checksum="1543A8E910229197" modified="2023-09-13" version="1">MSLKIKFGGKGKKRVLDTPTPTLVGDNEPPHPTKRPKRAETRQCPICDERIPLRLLEKHADLESERVDDIMSNIGSGDVNDQYFNEWASGEPGPSTRRLSALKARKSLSSSSSPIALIPHSIAFASQTIQQIKRHRKIRHARLKELLRADIEGEGDASGSPSWVGRFTGEEIDCPVCGLKVRGDEDVVNAHVDACLAYEGRRALEALEIEREREAEASYQAEDEDVEDTGTYVGDLRGAGFHTRDAQHADVDHEIDIEGDDLAVFGEAQFTEGDVVPVNQGTGQQHDSADEDADVNIEDDEGDDAQQTLRGLVAAGKKKQQQQATSLASDLTNDRMTLEEADVLDVAIAIARQRNDNVGLIAALQNKVKHLESCESGIDSASPLQPLLCRICLDPYDDPTVSTGCWHTCCKECWLRCLGSTKLCPICKRITCATDLRRIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF18</accession>
    <name>A0A9P6EF18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF18"/>
    <dbReference type="OrthoDB" id="2336871at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040470375" evidence="2">
        <location>
            <begin position="20"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="48760" checksum="ABC7D1C66F714CEC" modified="2023-09-13" version="1">MFSKSYFVVFFALSAFVQATPHHFPFFHRPGQQNGNQQLCENKPQATRTVVQTVTVTAKPTQTGGNNQVRPVVPPAQNVASSASSTKSSTKTASSAAATNTAKGNDNNNGGGNNNAGNNNGGGKGGNNGGNNNNDPQKSLTLDPRVIATGFEQDGQDPPVAGQVASLTSSNNFINYCLTVPNLPITNGKQITTGSCNPAPIGAIPSVDNIPSSKFESPLNFDTIKAGQSFTVVMNIKNMETGFFVNAQANYFGAPQQLNGQGQVKGHSHIVIEKLDSLKQTTPTNPKVFAFFKGLNSAAQGGKLTASVDKGLEAGFYKLSSINTASNHQPIIAPVAQHGCIDDAVYFTVTADGKPLANQGNGNDNNGNNGKSGATDNNTATGKGAASATGKGAAATPAASSAAAPAKASASPAAQNNDGKKSTDTKADDKTKQGGNTKQDDKAKISASSPPASAPTTPAQNNKGAKRRRMINRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF47</accession>
    <name>A0A9P6EF47_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF47"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="33010" checksum="C4A1999C56B9E959" modified="2023-09-13" version="1">MTFLTSCFNQLADSPSFLRLRRSKEKDLDQHPVSPTPAPKHSSSPTKASTISPVFGRPRSPFSPAGMSSYDHCDDSDESEPLLVSQPSSPSPVPSGAFSSLLSASSLPRPQEMMIVKSASSDDRLGLGLLDEPTIPSAPTTIPLLPTIQVRSKFIEPAIRTVNPFDYSSSGHKLDFSPNAFQLDKYVVNINRPLPLIGGSLPIPPPMENRVTSDAPTAYYTMEDTKSSAPATVKSFASLNQSPDRKTIDEHEAYLASLKLLRFGESSSQASYSVLSFTFDVIAETVDDDTTSWENVSLSSYGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFM2</accession>
    <name>A0A9P6EFM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFM2"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="63"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="59158" checksum="C3892E41FBFF2F35" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG93</accession>
    <name>A0A9P6EG93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribophorin II</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribophorin-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_875993</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SWP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG93"/>
    <dbReference type="OrthoDB" id="432292at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055374">
        <property type="entry name" value="Ribophorin_II_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23860">
        <property type="entry name" value="Ribophorin_II_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044286038" description="Ribophorin II" evidence="13">
        <location>
            <begin position="18"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II third" evidence="14">
        <location>
            <begin position="27"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="15">
        <location>
            <begin position="175"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9528342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="276" mass="30193" checksum="40A0C51E81B899F0" modified="2023-09-13" version="1">MLAALLSTLVLALSAQAATLKLQSPKLVVTDSMGTQLRSDSFSLSKQVAEAVELGAKDILKMTFQVLDQETGNGVQPHQTFLRFYDEKTNEEGIQPVRVTPGGKAKFELNLSKPPLSLPPTPNGDPLKVSLIIGTSQYDPISVELFDLVLPKSQPAPENPLESTFHVLPEIHHTFRADNKMPPQPISFAFIGIVLAPWAILLSLWSQVVPKPSRLFSPSILPFVASLGAFEGLLFWYWVDLKLGQVLLYGFMLSLPTFFAGKTALASIGSQRLGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGS4</accession>
    <name>A0A9P6EGS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_813288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGS4"/>
    <dbReference type="OrthoDB" id="2662268at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="20930" checksum="096532B4E8473FEC" modified="2023-09-13" version="1">MSNPLHCPLRSSQQSSYSSLGGAVPSGLSSLIRRLPQAVYTPSSKWQSATSRAGNHNPVTFDYPGRRSEGVRMQHLIVQDCSGLITGGTDMVLANPGLQKITFRIMWTGYTSDWVRPIEIVSNGPITRAKLGKLVAQNFARFIEIHSSTKTSEPAWAASRIRFDMLSLISLVNTCDENWQADVYVDFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI39</accession>
    <name>A0A9P6EI39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI39"/>
    <dbReference type="OrthoDB" id="338816at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180022">
        <property type="term" value="C:RQC-trigger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009349">
        <property type="entry name" value="TRIP4/RQT4_C2HC5_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06221">
        <property type="entry name" value="zf-C2HC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRIP4/RQT4 C2HC5-type zinc finger" evidence="2">
        <location>
            <begin position="71"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="31511" checksum="0C345C8E3EC5C4AE" modified="2023-09-13" version="1">MRRTAWTKQNSSLPSDRIKPQTKNSSNSNTGNKGKKQSIVELPKSLAVSQLESLLQALQKTSGKDKDPKGGCYCLARTHPLSSYTPLCYSCGLILCDVNLPQFACPDCASALLSEINRKSLIDQVELDISDTIAKEIEDQERAIETARMAAGAFPTLGAPSLAPAETRLQSPHSLPVQQTHKVMSLTGSKNRVLVSSFTTKPPTTPRALQPKDELVEPTVNRISPPHAPPLTTRQPRGDIPFENLLEGNLEYVSQADSNATLPGGSMKSSRRRKNKGKDKESSERTLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI73</accession>
    <name>A0A9P6EI73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_906089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI73"/>
    <dbReference type="OrthoDB" id="2526683at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026768">
        <property type="entry name" value="YPEH2ZP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31841">
        <property type="entry name" value="PROTEIN FAM72A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31841:SF1">
        <property type="entry name" value="PROTEIN FAM72A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14976">
        <property type="entry name" value="YPEH2ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="35491" checksum="00219CB862B8399E" modified="2023-09-13" version="1">MPAPVMNLHQIAPPQMYNYVHLFPNNPYPQPPPPIAHKVWILDCKTCGAFLTNRAMKAVLLLRPNVSLYSSDALPLNCSAYSSNPEALRPPSVQKAGSMSAPSRTCECLTQTLCCHGCGTAIGYMIVIPCARCTSSITASNRATNGHRFVFHSTEVAGSERHYIKDEPSVVPYEPPPALPTPYYTSYPIQEQTMTRSDFLRTPPLEYATPDLIALRNRNMESSSYLSRAQRPPTPQSPPPPFSGDPLSPRPSSSSGNPPPFVGSSTYHGDQKDSGITLQRLKPGDIVYWHHLSRCGEIPGVEDNRRARTANTAKAAGRMVFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EID3</accession>
    <name>A0A9P6EID3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_763505</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EID3"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="75"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="57921" checksum="7F65677C523550DA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJC3</accession>
    <name>A0A9P6EJC3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJC3"/>
    <dbReference type="OrthoDB" id="3238099at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="56522" checksum="5CD0819DDD96BE9E" modified="2023-09-13" version="1">MSVAFSGPALPPEVWSHVLRESPKSSLVSLLSVCSIFHDIAVRYLFSSIKIYFVGVRRGEVMLNTNHRHWVEEVARKLMIKSWELLNHISEEPSFARVVKSLTVISFADGFSIFERMTLANTLLSIPNLETFRWIGNHPDFGSTVAEYLPTTLRRLEIQASLPLESLNHISRLESVHLSMPWFFPDDEEAHDSWTNDEDLFDLEDPDNLTLESMFQTVGPHITNLRISGSQYGAIPVRIFNCLLDLEIFFLGGEDETVGLDLIFHHATQLQSLTWIGYINRRAYTFLPPSTSTLLPNLTSFRLSGVFDFDDITQNPTDRTDFDCLLHFLQNRKLLRRLYVRLPDLHWPLGLELWAIAKTLDKLEILGLHTGEGQIGEGDLNRILDLLPRQLRALHVAFDCGANNLLPLLDAIASMPNLSFLHLYGTISRLPILLEDLAAENKQLQMIGLNRAIWDIERVGHGIVTNKWPRWKIKFNVEEDFLNEDDAWLFHYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJS8</accession>
    <name>A0A9P6EJS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-deoxy-D-gluconate 3-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_187287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJS8"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF5">
        <property type="entry name" value="2-DEHYDRO-3-DEOXY-D-GLUCONATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13235" checksum="83CDEAA76311DC3B" modified="2023-09-13" version="1">MVPLRRGRIINFASLLTFQGGITVPAYAAAKGGIGQLTKALANEWSKEGICVNAIAPGYIETDMNEKLLKDEVRLRQISERIPAGRWGRPEDFAGPVVFLASKASQYVCGEVLVVDGGWMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK53</accession>
    <name>A0A9P6EK53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_734560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK53"/>
    <dbReference type="OrthoDB" id="3269227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="131" mass="14596" checksum="98E13CED11EA4263" modified="2023-09-13" version="1" fragment="single">MFGLIRRISHGVIPRPDRPWEEDPTSNAPQRNRKRRLSSPERGEVDEEQSEKKKVRAESSTPSMADTEATFLTPVPQTENSEVKEVTQGVKEVDLDDKEAQYSDSAETTAPESVPLPEEQSGELDEATSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELD8</accession>
    <name>A0A9P6ELD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium-channel protein CCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_850197</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416585at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000093">
        <property type="entry name" value="Calcium channel subunit Cch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="702"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="731"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="939"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1008"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1253"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1294"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1333"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1378"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1507"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1587"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1621"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1651"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1705"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1805"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="533"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="810"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="1251"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="18">
        <location>
            <begin position="1586"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="246"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1102"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1102"/>
            <end position="1114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00061395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00067459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9530724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2140" mass="240440" checksum="5F643A32056B5E11" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELN1</accession>
    <name>A0A9P6ELN1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_849275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2562681at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04774">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="14773" checksum="C03701E5637DDCC8" modified="2023-09-13" version="1">MTRTERAAYPRAVNKDRSESRSGLDTSLRKSGAGQHNWGSLADERRIETDAARDEAEERASSPEADDAKPSLSRTSSISDEELEKARKYRKNALKKGAVDLTQIARTSAAVSGSPPSPVSATSLARRLSRENTKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELS7</accession>
    <name>A0A9P6ELS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_106319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELS7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="16964" checksum="0E08637B0ED68502" modified="2023-09-13" version="1">MSRIGKAYKSDRGLVGKKRSQIQMRPCTFDSTPQATGSNPLHLVIRTSRSPEGTALGLPTPDASPVDGSRTQNHSISGNSPASKLNSERVEAQNAPTLFPGDSICSAEPRLPPSPVSPVRPSLRITIPKTHITAADQPKAPVIPSGSGDALWDGRSSGSSTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELY2</accession>
    <name>A0A9P6ELY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_892290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELY2"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="29056" checksum="7413F28D83E0E88E" modified="2023-09-13" version="1">MSDSRLPLKLSTDTGKNLSAYLLALRWNMSRIVLVTGASAGIGFELVHLLAEKGHKVYLGARDLTSGEKALDKLTSDGHKNVKLIQLDVNKPSTLYAAREVIEATEGKLDALVNNAGIGSLHLDQNALTVDVATIRETMETNLYGLIATCQTFIPLLRKSISGVPVILNVSTALGSNWTQAQTDSLLRVVAYSTSKAAANSYTIALAHELKDEGFKVNAVTPGFTSTKLNGFHKGGKSARDGALVLLPWVLLDKEGGTGLFIGENQKEVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELZ2</accession>
    <name>A0A9P6ELZ2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6830 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_762138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELZ2"/>
    <dbReference type="OrthoDB" id="3232986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6830" evidence="1">
        <location>
            <begin position="569"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="836" mass="94342" checksum="224FFD3A42D5D4CD" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EME8</accession>
    <name>A0A9P6EME8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_761185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EME8"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="168"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="460"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="61587" checksum="951230B34F74A865" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMY5</accession>
    <name>A0A9P6EMY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_881023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMY5"/>
    <dbReference type="OrthoDB" id="2909885at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52309">
        <property type="entry name" value="N-(deoxy)ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040490849" evidence="1">
        <location>
            <begin position="23"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="14485" checksum="EE809A2C5D054FA9" modified="2023-09-13" version="1">MCNVKYIILVFALAGLRHFVQFAKIARTVSKLKQPHNGAVFWSGTRTNEHGKTVSVIHDAVKHAESMGGATVEMTMKKKGVSIAENNKYSPRLWNIASEAYAKNAKGDIHVVMSETSGPRVFGTRWRDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN05</accession>
    <name>A0A9P6EN05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN05"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="30084" checksum="F34093D3544BDE52" modified="2023-09-13" version="1">MTQETAVDTFGFPVGYFVIKSVATGKVFDVGGDSIEDGTEILLFPEKEKSLVESFRDPSTNNQVFFIDTSGALCSRSSGHALDIEGERVVLRHRRPISQPFPNSYAHPLPKFSYRQKTGEITVHFGYDPTYPPPTASPSANWTTRTYLLTAVPQRRPRTMLDNASEFFASNFLTPISLFAGGPPASPARPDHVFDGEIDLRDDDIVEEERGEEGEVDDDPSPCRELRIVTASTSEKEMMDLLLSERARQRRRWVILPLRVSTARSRVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENC1</accession>
    <name>A0A9P6ENC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Translocase of outer membrane 40 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_784354</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Channel-forming protein essential for import of protein precursors into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENC1"/>
    <dbReference type="OrthoDB" id="19656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000009">
        <property type="entry name" value="Mitochondrial import receptor subunit TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9" id="KW-0626">Porin</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00053390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00078731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9533006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="351" mass="38215" checksum="F4CC310EB5B488BF" modified="2023-09-13" version="1">MAAPTIPLHEKDALVNPYAPEPTVTSSYFNPVSPFFNAYDRFARWRADLGLPQPGTVENLQKEVKGTHLSNYIFDGARADLTKSLSMSPLFQVTHSFALGSQTLPASYNFGAIFANSSVFLQGSVDHEGSMNARFNNGWNANNVTKAQAQLSSNIDQSMIQLEHDYQGSDFSANIKAINPSPRDLTGIYVGSYLQSLTKNLAVGVETLYQRPTPNQGETSTSYLAKLTGSERNWTATAQLQPSGVLTATYWQKLSEKVEVAADVQVLAAPQRRDAIATLGAKYDFRVATFRAQVDSTGKVSALLEQRFVPAFAFLVAGEIDHFKNSAKVGVGVMIESSSLTPEEMGMMPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6END9</accession>
    <name>A0A9P6END9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_760318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6END9"/>
    <dbReference type="OrthoDB" id="3247214at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="407" mass="44270" checksum="65BF2B13A7E7B284" modified="2023-09-13" version="1">MASTVSVSSPSPSEPSNASSNTLSSRFPAAVSTISRLKSFSSNFIQTHRPPPVVFPPPSWDLSDDNLGAGRSATPTLPESNDEPMVEEPPEPVSFAAKLKSMIEALPIPGSSNPEPAKDDEINPPSPVPSDLDKSMVRMLSSEQVMNGASSTSKEGGSVWNILAGLKQGKRDDTSKPSVTEEEEHGLMMYAPLEPKADSEVELATSETIVEENDKKTEVATPPNEDSKSTEEIIEKHVWVPSTTELSVLTTWWGYRIYLPPAVMAKLNGKSLQATARAAMLTTALKWLLNKIPLAIVPPQFRPAVKLLKTLTPLTGYIGVFIAWSWERISSLDNGNGVVLTATWLLPVALLPMAWDAGAIFRPVAAPTPEELKAIEEAALKAAEEKRKAEQPQQNQNDQKKKSFFHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENH2</accession>
    <name>A0A9P6ENH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_41883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENH2"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="36531" checksum="8888377B4E67232B" modified="2023-09-13" version="1">MLKNPPYPSAFVLYTQGQIFGGCLAVAIWDVLCHLLEDFQIVFLQQFTWKTAVFLVTRLTPIAYFVTVLMRTALTQVNCDAVQPIFRVLLVVFRSSTTLLLLLRVDAIYRDNRPLRALFLSLWLLTLGAFIYLSARGMVTLSNHCLVAIEPVVALPGLCLEILNDTLICLAILYKLGGESWKERGRSLRNLLRPRGSSLSEVVVQDTLIFAGIAIFANVCTFISCLGVVPLPEELDIGFGLLHPGALLVNMIALRIYRNMKLGEPGLISSAPTTGSLRISNLVFNVPVSNSDIVAASEVSGSMTTGALTRSGSVSFHEGKPLEMEEKGQTTLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENI3</accession>
    <name>A0A9P6ENI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_807430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENI3"/>
    <dbReference type="OrthoDB" id="3163292at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="680" mass="77945" checksum="9ECB45EB6BB89E2C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENQ0</accession>
    <name>A0A9P6ENQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_759631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENQ0"/>
    <dbReference type="OrthoDB" id="5595695at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01299">
        <property type="entry name" value="Met_dep_hydrolase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057744">
        <property type="entry name" value="OTAase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="116"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="55111" checksum="D0BFD757CB797875" modified="2023-09-13" version="1">MKTLLLLPTQTLPAIHPTTHPHLSLPPLPHPQPQPPTPPNQPRRTIYQLRAKYLFDSVSRVLVPNQVVTVDESSGVVLGVCEGGDEDEGEGWKKMLGLGEQTGDVKVEKIDLGDMVLLPGFVDVHVHFFLHPYSETSWDDQLLKESLAERTIRATNHARQTLLAGFTTVRDLGTEGAFDADIGLRKCLSGPNPIIPGPRYYCSTRAIISTGSYGPQSALYPSQNGVDGVMGAQPVDGVDECVKEVRKQIGAGADWIKIYADYRIRARQSDVSSTLSTKSISTFTPTELAALVNTAHSRGVKVAAHANSAPAISHLLDAHVDSIEHGSGLFDASTCDKSLIRKFLRNRERTTWVPTLSAYYTSWLNAGGSEAPSDSYASEAWRRCQEAFEEVVMRHAPMFDNIAVGGDTGVYEHGRNGLEMVLMRRYGAGWERVLGWGTLGGWKCVRGREETPFGAIRVGWAADLVGIQGKLDGSADEFEQAVMEGVSFVMKGGRIYKRDGRQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENR0</accession>
    <name>A0A9P6ENR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENR0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040194830" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15398" checksum="1F16D26C411D7726" modified="2023-09-13" version="1">MLLFLCGIVCCSDCCSNECSLEFSLSLTETRSTAPRQRLSSKASRKRNVFSEARIVRVCLRPTYWTFKADKTAPPRRAKDIARVSAPEDPRCWSNIPAEQGGFTGLLAFAPSFLLSASTIQGIKLLRVQLVQPCRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENZ1</accession>
    <name>A0A9P6ENZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_624424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENZ1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="79" mass="8683" checksum="2AEC19E27688C38B" modified="2023-09-13" version="1">MDRDSEYSGSSDYLPLSLAAKHTPVVLIGMSGNAFCLVAAYSRRVPHRKFYLCIAYTALLSTHPPAIPISSTFPEQFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP24</accession>
    <name>A0A9P6EP24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_758194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP24"/>
    <dbReference type="OrthoDB" id="3221808at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="34"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="164" mass="18091" checksum="1B576FC0F661C11E" modified="2023-09-13" version="1" fragment="single">MSSPEKATPDKSFAEPFPEISGVYFHDLEAPAKWGVVVDHLISKEKERCEIWKDEVTNILIFAGLFSAVVTAFIIESYQSLQDNPSELLLARISANLEFFANKTAGAPAILPASFVLNGPSLPNKLLNALWFMSLILSLASALIGLVALQWLREHLRPSTRNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPN0</accession>
    <name>A0A9P6EPN0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPN0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="52" mass="5857" checksum="B6383624277029D4" modified="2023-09-13" version="1">MIHVERAAYRFFTRRGIMDKLGSQFGDSCSTFFVFTSFGLLVTTQETLGKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ27</accession>
    <name>A0A9P6EQ27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_630475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ27"/>
    <dbReference type="OrthoDB" id="3263941at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF2">
        <property type="entry name" value="TRP C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="424" mass="47726" checksum="5893EB9F89F1FF3F" modified="2023-09-13" version="1">MTARYDRRQIYKYSLSLMNVRVLYERITLNRLTTCYTIAVLISCVVLISLQAVTFVDNSQAITRLTPIVRGPNVPTGIPIELGDHKLFICPSLYDQTAKSCRLIVDFATNVQTPPALSNVLPESCVISLMYLDDIVHNARREDVVTFVFQLWMLGVSLFAIIAQSIPHISAVFLGHVLGTIWSAYRLASTTSMRTFYQANMVPKACGGVDVVGNWWNVRIGHDIATTVLNILVLQIISFLSFKLYNIYTSQTRARVAASPQVYSAYKFFLLFAAVLQLSVFYALASTGMWIDKVSHAPLKQLATHSTLYLAGFIVSLIFQVPWLLFGWTTIRYEGRILFLAFLGISGGLLILFTVIFFSHIYLYTFVSWPFFGAMTMTSYVLLVLTTVLAVICRLKFGQGLAEFLNAKEELEAADFTPVDFQYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQL5</accession>
    <name>A0A9P6EQL5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="7">PPIase</shortName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_903399</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQL5"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000008">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>cyclosporin A</name>
            <dbReference type="ChEBI" id="CHEBI:4031"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="60"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>cyclosporin A</name>
            <dbReference type="ChEBI" id="CHEBI:4031"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="89"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>cyclosporin A</name>
            <dbReference type="ChEBI" id="CHEBI:4031"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="99"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>cyclosporin A</name>
            <dbReference type="ChEBI" id="CHEBI:4031"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>cyclosporin A</name>
            <dbReference type="ChEBI" id="CHEBI:4031"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>cyclosporin A</name>
            <dbReference type="ChEBI" id="CHEBI:4031"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001467-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="17133" checksum="49171ED33C23F793" modified="2023-09-13" version="1">MESVVLETSLGDIQLELYWNHAPKTCKNFTELTKRGYYNGVVFHRVISDFMIQGGDPTGTGRGGTSIYGNKFEDEFHPDLRFTGAGILAMANSGPNTNGSQFFVTLGPTPYLDNKHTIFGRVSSGMRVVQRLGAVGVDPQDRPREDIKIHKGRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQR4</accession>
    <name>A0A9P6EQR4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cys/Met metabolism PLP-dependent enzyme-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQR4"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="437" mass="46586" checksum="48A9914BA3B33574" modified="2023-09-13" version="1">MASSFHRQPGFDTLQLHAGQIPDPATNARATPIYASTSFVFNSSEHATSLCSGKEPGHIYSRVSNPTVEVLENRIAALEGGVAAVAVSSGQAAQFLAISTIAEIGDNIVASSLLYGGTYNQLKVTFKKFGIGVKWVTDPSPDAFAAVIDDKTKAIFVESITNPKYIVFDIPALAKIAHNNGIPLIVDNTFGMGGYLLRPIEHGADIVVHSATKWIGGHGTTIGGVIIDSGKFDWPKSGKFPGFTDPAAGYHGLKFSESFGASAFAFKVRLELGRDVGTALNPFGAFLLLQGVETLSLRGQRHSENALALAQTLEKHPNVSWVFYPGLKSHESHELATKLLRRNRYGGMLSFGIKGDPKLAGKLIDNLKLASHLANVGDAKTLVIHPASTTHNQLTEEELLLAGVTSDLIRVSVGIEDIQDITADFETALEIALDSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER81</accession>
    <name>A0A9P6ER81_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="3">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_903010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="3"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER81"/>
    <dbReference type="OrthoDB" id="7773036at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="7">
        <location>
            <begin position="7"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="379" mass="40841" checksum="0261F6F57AD7E703" modified="2023-09-13" version="1">MNPHLWSQTPLIYSSKLSQITGANVYLKLETLHPSYSFKYRGISHFIQKAKQIHGPSVHLVAASGGNAGVAAACAAESLGLRCSIFIPEGISTSTLEVLKIHGARVIVGGRFYAEALEAAKLLVSNESQAIIVPAYEDPIVWEGHSSMILEIREQLPVKPDAIFCSVGGAGLLGGIILGCKDVGWDDVSIGTVETNGCDCFYQSLSLNANRFNSVERKLPEGVSLVHDSTHGVYLAHLSSFSSKASGSLGASQPSGGVVKMALERTGRVLTHRVPDELSMEALIAFADNQKILVELSCATALVPAYHPTLFGKIMETVPRMNQEEAPVVVFIVCGGFKIDLVTMAEYQNDIAAIKTSIDEWIVKCDDGELFRIPIDRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERB6</accession>
    <name>A0A9P6ERB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T-complex protein 11-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_890363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERB6"/>
    <dbReference type="OrthoDB" id="276323at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010737">
        <property type="term" value="P:protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="671"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="671"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="710"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="803" mass="89213" checksum="BEA74E7EA579A3D8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERG0</accession>
    <name>A0A9P6ERG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_844684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERG0"/>
    <dbReference type="OrthoDB" id="3071584at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="59683" checksum="5C0517EBBC4E3368" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERR5</accession>
    <name>A0A9P6ERR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RF-1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_783055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERR5"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="166"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="226"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="30265" checksum="E776B743DBD6A519" modified="2023-09-13" version="1">MSISPVLRAASRSAYRDALRAASVTFSGDAPVLQAFRMKVRTDISQQDASSPELFVKQTQFIREVADVLRKNIVQGERLGESSPENPVYRIRMTKNTELGDNDTIKNPAPTESGRGARRRPSNFCADAALAEDSDIESSIPNSSSPNPMNFSALKRAHKVRVVPELLESDLEESFVRGSGPGGQSVNKTENNVQLLHKPTALRVSCQQTRSLSENRKIARKILLEKLDKIQNPGLSKGEMKAAKQRERERRRRKKAKKKAQKAQDEPDSQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES57</accession>
    <name>A0A9P6ES57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mg transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_805791</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES57"/>
    <dbReference type="OrthoDB" id="666972at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228:SF7">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="132"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="384"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9533679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="534" mass="57844" checksum="1DD44F0AFBE68DAA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETB3</accession>
    <name>A0A9P6ETB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_325312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETB3"/>
    <dbReference type="OrthoDB" id="2275560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000005">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="377" mass="42776" checksum="31271D45A0CAC02B" modified="2023-09-13" version="1">MSSRQASVSDPRPPEDEEHIDGAGEGDEVMEEVEMQEEGYTSSTPTSTLTWISWFCSLPGHEYFCEVTEDFIEDDFNLTGLNTMVPFWKEAMEMVLDVEPEDEDTSKIPDVSIVESSAEMLYGLVHQRYILTRAGLQAMVSQVSFSTTSSVPFHIHVHFFYLDGTSANPLNFPSQLLFYQQAEKYESGVFGSCPRVYCVGCNVVPCGRVDIPGNDTVKLYCPNCNDIYVPPSSRFQGVDGAFFGTTFPHLFFQTYREWAPAPFWKALTTGGSPLSPRSPGTQPAPRQPTFVNPNQHGGQKRAAGYVYVPRIYGFKVSERAKSGPRMQWVRLRPESPEELDMVDWRGRWINEEDEYDDDEEEEEEDRQMEDFDPVGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETH1</accession>
    <name>A0A9P6ETH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_802878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETH1"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="186"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="601" mass="68135" checksum="981390AA6CBCB435" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUC0</accession>
    <name>A0A9P6EUC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6741 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_755665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUC0"/>
    <dbReference type="OrthoDB" id="10268011at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046629">
        <property type="entry name" value="DUF6741"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20526">
        <property type="entry name" value="DUF6741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6741" evidence="1">
        <location>
            <begin position="3"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="14243" checksum="6255ACBAF78771FF" modified="2023-09-13" version="1">MPGSTHIKFKRKGAFMGGIGLDEAQSRIKLSNNDHYSFHDLHADGRRRIHLKIKWTGYSSLTYEIPLDGYDGRVDLQTVARRVSRACVHYLQANVIPVVWDRVVLHHLEEVQYGVWQPMLSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUE8</accession>
    <name>A0A9P6EUE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLI interacting factor-like phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_888831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUE8"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="195"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="47563" checksum="18DA59BDFB4AC2E5" modified="2023-09-13" version="1">MNTLGYVARQFDGLAKTPPSTPTREQGDLPRVSSWSTRSLLFNNGRTRPQRSQSSPHFASTSATTTATTTPPKPPPTITIDPPTLTVVTPAPPRSKKHIETVIDQIFFLRVFLLVWDHLKSAWSSLAEGIAVLKWRLDVKGKGKAIESNLVLEPALLQHSLDSARTATPTLESLSPPATATSRSTTPTLSARKTPFHRPKTLVLDLDETLIHSTSRPISVQGGSGLISLGSWGKGDKPAGHMVEVVLQGRSTLYHVYKRPFVDFFLRTVSSWYTLVIFTASMQEYADPVIDWLDAGRGIFAHRFFRDSCKQLTNGSYTKDLRVVEPDLSRVCLVDNSPVSYTVNEGPQLICQNLLCTLLTIGSRSFNLLALYRLFNKSANGIPIEGWTHDPSDEALLDLLPVLDSLRFTSDVRRVLGLRKAGAYILEVDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI32</accession>
    <name>A0A9P6JI32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157993">
        <property type="protein sequence ID" value="KAF9521750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI32"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="35526" checksum="6D7B9ED9AEC12BEC" modified="2023-09-13" version="1">MDTYIFAEVSASHVSLPTYDDGPLLAVNSGRVALTPAVPRSNHDWNTQTGVPTGQVQDPLYIPRTFQHNDPSLVERLERIEHKLDALSSRVGATVLEGSGDIGPTETPKITFYRVPAPEPVEPRFAAPFNHFLDFHLPTSHIINTWNSVPALVLAQQHVKQEAESFYADAVARVHVDKKQFLNWGIPHKLQRGDLIDISCTYSLENGNTSECCPETDIPGDSKYFVEGTQNYENSNETACVRVAAYHSNGYRAHGVRTLWPDRILVVPGQFNDAEYPPSLSFLALTQTFSRHTSYPGIRAAAKYNIYAMMQNLWSLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIF8</accession>
    <name>A0A9P6JIF8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC6 like cysteine cluster associated with KDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_777339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157953">
        <property type="protein sequence ID" value="KAF9522257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIF8"/>
    <dbReference type="OrthoDB" id="3055037at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040898">
        <property type="entry name" value="CxC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18721">
        <property type="entry name" value="CxC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040299734" description="CxC6 like cysteine cluster associated with KDZ domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="CxC6 like cysteine cluster associated with KDZ" evidence="2">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20632" checksum="5F008D44D91BEFFE" modified="2023-09-13" version="1" fragment="single">PGLRGEYVWDGFILLSLLWHHISRGTCPVVLHSGDQSKRFEDAMIQQNTEIKNHGQPEWAHFCDKCCRTWTDKAHCPKPLVKNSDRFCPNYKAQINVCAIVNCSNAADSGYMTCGLKRHRESDENRIHSNKGFFQLQSRLAHQKVSHPNNAFEAQATEEGIEEETVLETNEQDLSGDALGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIQ6</accession>
    <name>A0A9P6JIQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_115209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIQ6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="547" mass="60657" checksum="2A4A9C275F6BEBC0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIX1</accession>
    <name>A0A9P6JIX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_918240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157949">
        <property type="protein sequence ID" value="KAF9522349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIX1"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF1">
        <property type="entry name" value="AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="106"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="311" mass="34714" checksum="59FFB2EF92047D63" modified="2023-09-13" version="1">MAQFDPTHHLSRMSKSRKVSPVQGLHKFLGTPGLISLSGGLPNPEYFPFGTLTAEVSTATKFSEGNDTTASHKPPRLADWFWSFFPSSNGSEMTSSITVPKYANRSQPDALQLSTALQYSSARGLPLLNSLCREITAKVHSPAALCDPSNILGASRDILLTTGNTDAWIKCVQTFCNPREAVLCDDWTFSTSLEGMRPYQVGAVPVKMDSQGMCSTDLREILEAWNETERGYQRPHVMYIVPIGQNPTGSTMGSLRKQEIYQVCVEYDILIIEDDPYFFLQFNRYCPPSERLELKNTDESYIQSLSPSFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJG7</accession>
    <name>A0A9P6JJG7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_776171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJG7"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF2">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="17750" checksum="7107CB5A683BEE70" modified="2023-09-13" version="1" fragment="single">GGNYNPPRSMLDLYTPRFVKGKGVEKVGLCPICVEPIERGGENKKIWLAMKFSAFNYHMQYAHGISASTGKPFSPPVAFQITSRPNPGKNEKSEIQQGKCHKCTKWVAIEGIKDMESKVSWKHAAACHQDSWLEGETDYFEQDTIYSTFLALERSSCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJR6</accession>
    <name>A0A9P6JJR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_910793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJR6"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09804">
        <property type="entry name" value="Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="380"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="484"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="576"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="768" mass="82959" checksum="FF66DF164F11C96E" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKF9</accession>
    <name>A0A9P6JKF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_649611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKF9"/>
    <dbReference type="OrthoDB" id="7961613at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9565" checksum="E8372066627818DC" modified="2023-09-13" version="1">MVRAKLGVLDYVQRGVAYTCVGLCLYAVTMSVLIHRDTMRRGQGLMDERVKQGLPIPTTRKEEPSQEIEQTLAEQAVAIFKKRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL24</accession>
    <name>A0A9P6JL24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_820274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL24"/>
    <dbReference type="OrthoDB" id="3267813at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040212330" evidence="3">
        <location>
            <begin position="23"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="50746" checksum="CCAF3033BEDBE972" modified="2023-09-13" version="1">MFLRHPIFLPSLLLLAISRTSAYTWKFQQQPRECSNLTVSVKGGQPPYRLLIVPSGMYEGDPNTDPRRILQHAFTGNDKEATFQLKYPVSSQFVALVSDASGFASGGTSTSITVGSSPNLDSSCLDNPDPNAFYFMLYPNEIVQCAYNAFSLDPGNSLKVQGNPNYLGIIPGGQSFEIPRSNVSTDGSINWQASLKSTTTLILVAGDARGRGSGGSAVYTVGVGSTFDNSCLDENSPSSTPGNPAGGYPTANGNGGSGHSMRLNVGAIIGVALGGVTVLVMSVILLWWWRRKHNQRRGLRAVLLDRVDDDVDHSEGRGRKARKQPRVQRPIHHYSPEPFRFMSSSNSLNNPSSMSSLVGFSSRGGMYQAKPGAMASGGETSGRRKGLPRTPALAVVNVIQHDDAGPPLSPPKDLTVPTIVELPPAYTALKRLQTWRAAAAARRSRGRSAGAGNVTAGRSLSRTSEQVRRDGRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMJ8</accession>
    <name>A0A9P6JMJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_817959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMJ8"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="134" mass="14627" checksum="748DC8C22E4D9C43" modified="2023-09-13" version="1">MYLDAHNSFRAKYHAPALTWNATLASKALEWSSKCVFEHSGGKLGPYGENLAAGTGGYSIADGIKGWTDESSSYDPNNPTYSHFTQVVWKSTTELGCAYTMCPDGSIFKDGNYGPAKYIVCEYFKQGNVVGQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNJ2</accession>
    <name>A0A9P6JNJ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_857109</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNJ2"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="25"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="45600" checksum="6255479689E6BF6E" modified="2023-09-13" version="1">MSNIFANILSRIYPPTEASHITILGLDYSGKTTLLYLLKLGEIVQTIPSMGLNVESIEVPLPSRGNKSGGTFKMTGWDIGTGCASPRQYIGMLRNYTHFTRAIVWVVDSSDRERLTESTEMLTEVLFSITNLGEDIMKIPILILANKCDKSNGLSIDEIRTAFTKVTTGRLISVFKSQATLQTAQNPQTSGLPQAFDWLNTALEIVQASEKTGRSITAVPQAPAGAPENDAQRAQTVLAHKLESWLNRSEDSDLSDDEYLERFKAYTLPEWDHYTHIRIAYIILTKHGRQEGKNMIFNGIQSYIANSQQTKGRTFHITMTYFWIQIVHLGIRNTPPPQPNQSNLSPLKEFTRFLLINPNVVDGNLWSDYYTKEVLMSPKAKEEMVLPDKKPLPNLVTRDAITSFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNJ8</accession>
    <name>A0A9P6JNJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNJ8"/>
    <dbReference type="OrthoDB" id="3351617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="36501" checksum="EB023AA76F6E9A5E" modified="2023-09-13" version="1">MSSSSSSGSSGSAFVPSERACFDGVMLTALAYGALVMVCVQTAQVLLYRPRRDQTFYLVILYTSIVFPLTTAGFFGRLRFAELTYVVNRNYPGGLKQYSIDHSDQWASYLSKVCTTIMPWFADLLIFYRVFILYGNRCWFMILPFAVFLGRIGTSIPGLVSALHPSHPLLYTNIFNITQGATYLALNVFVTITIWLRLYHMRYNAERILGRLQASMYNSYSTLFVESGAFFTLWSMVYLMLRVTNNWAQDVFWQPYAYVVAITRMLVVLRMAQNRAWTRDIIEAAKSGIMDWRVSSTGSIELSNPHLDRIEKAETVGFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNY6</accession>
    <name>A0A9P6JNY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_743002</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNY6"/>
    <dbReference type="OrthoDB" id="3361892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032931">
        <property type="term" value="F:histone H3K56 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016849">
        <property type="entry name" value="Rtt109"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF2">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE RTT109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51728">
        <property type="entry name" value="RTT109_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9527581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="518" mass="57666" checksum="2256B38E9F2570EE" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPC8</accession>
    <name>A0A9P6JPC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPC8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="69" mass="7991" checksum="CDDCA964616F5F62" modified="2023-09-13" version="1">MHQHHQLLEFSLFATFVFLSGFFGFNKILRSPSTTLFNCKIAIVMVVVCRQKVRGLKKQSQRCRQGCVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPH6</accession>
    <name>A0A9P6JPH6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_836549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPH6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17061" checksum="B05A275F990E90F9" modified="2023-09-13" version="1">MENNLPRLANYPRPDAIRAFLAPGRLFSTEVLVNGAPGIRSPNTADIASLRLSSQPITVLSLGMRFVNHSAFHDLAKFLPPLQKLAVHIAETANIGTVPKDDADVISRLMLDILPLPQFLHILGLCHVKQYKAWICSSCQIPRINVSVAGFVGKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPJ0</accession>
    <name>A0A9P6JPJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_906952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPJ0"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="29078" checksum="91FBE46871E2F9CE" modified="2023-09-13" version="1">MVTLEMKQKLRTRHEGGKNEKTRNYHATNYREALNEKNRWLSLPTELTIAIFLLCDAVNSTWHEWSLGPGVDDISHFSLPIEFILSSICRRWRYLSLDLPALWKRFVYIRLPSGFNFGDFPPEKLSIYEERSGGQLEDIYLDIFNADYKNEFAKFIDDIFLRHSQTLRRFSLISKGAFEISFHLLDLFPDASVPNLEYFAAFAFLKNGFIPPEMGGVKPELFMNGAPSTYVAMASSPGMVFRPQQTFPHCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPQ1</accession>
    <name>A0A9P6JPQ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_928850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPQ1"/>
    <dbReference type="OrthoDB" id="2610860at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="45041" checksum="9DBB79B94D99A6DF" modified="2023-09-13" version="1">MPNLFVSPQFKVYESSKSRGCSTVSLQSAHEKGSNEGVADFAIFCAEARHRYRRSTAVSDPRFPIKFSEWDQVAIGKSYRCVALIELKTPPRRSIKEQSVFLETLQAAFSLAKIQLIYYAEVVFAGDHKPEPDDELVLIAGVGEWWMYAIVMNKHCKVPDQRRLEDEKVYYRDNSGKKKDAKAKQRTQPQRHHEIVNNTDKVQIPANGNWSALLRLGTKESERHLEPLYKHLQKLKEALGNTTTYAEEEVSEDEMNIMSDEPDDAQSEESEDDYEEDDEEDEIEDDFKRPIVSHGISVFREENGRKIQLEDQYQATVICSNSDIDINTTSNWDWNWNSSLNEEQRSKRRESRDRVREREKLEHFKEDETDERLKNEKVKREKLLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPY9</accession>
    <name>A0A9P6JPY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_836009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPY9"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="13"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="45947" checksum="4F0DB6F9603CA4E0" modified="2023-09-13" version="1">MVRLTQAGKQALDAVVAKLAADPEVGTFIFGVTDADGEIYVKGDGYNVLGDSNSGEVSLDSVFWICSQTKMITHVAALIAVQHGVISFSDPVSKYLPQFATENLIVLVPGSPKDKPEYTPAKTTMTVQHLFNFTSGLSYTMPPARDRQITEYTAEHAEVNSIEKFINLIKGDLAGVPLNFEPGTDFVYGWSSDILGFLVEKASGISFEEFCKRNIFDPLRMNSTSFYQTPNLRSKRVALNYLQIDESGKKQLGLHDPNIRLFETDPKKVRLHLGGVGLYASAKDYLAFLRHILQLKAGTAPNPILNSEYLAKVFEPALPPSGQKSIQRLLAMVEAALGNGVEGMWQWTASNAVTMKDKEERRKKGSIAWSGWANTQHFLDPTTGVAVILQTQMVPPLNVSVSKYYDELEKALYAGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ13</accession>
    <name>A0A9P6JQ13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_835875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ13"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="18855" checksum="B16DD18F9BCC39E5" modified="2023-09-13" version="1">MNVSSQIFIKVIMLLAGIYGLYWGLPLRFGLCEFSHETFKYQPGYSNIRLFTTLSAHWVLIILHQRIIKAKFAMGKGCVIEEVGHCLIFDTVVLVLNAWKIGKEARRPIYTSSSGTRRTLTLTQIVYAQRLIYFVFALFLLVNEALISIIASRAVRALLNLSSTVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ53</accession>
    <name>A0A9P6JQ53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_854295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ53"/>
    <dbReference type="OrthoDB" id="2428527at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="42282" checksum="3352BBD568431C30" modified="2023-09-13" version="1">MDDSFQFIIESPQHAQGHKKRPRLVTSCDNCRLKKIKCLQPSPESKCEACKAAKIPCRFRDRERYFAERSRAIAGPNSSVYASELRSDGKPALDAFSVASGSSSPSISSHSDPRSNSHSPKASGMVAADADTLGRYAPYSAHDSRHVGHGHVRSNSSISSFDSIRSNPALQYNYQAHTSSQMLHYPTNSRPNSYQPDYRGLVLFDPENPQRPGSNLMAHFIQGFFETYSHEFAFLSYQEVLNDYWEHRLNNILANCIAAMAVKHTNLPELQMSTRELHNIAENYIDVAKTLLNNVSHIPSLDTLQAIMLLCWFEHQHHRLPGFRTFYGMASKMSADLALQDSNYDPMSEYERSRRRSTWGGMVQLHMAANNFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQX2</accession>
    <name>A0A9P6JQX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_812665</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQX2"/>
    <dbReference type="OrthoDB" id="10252502at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 12" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9529293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="402" mass="45502" checksum="AC61B2913BF070C3" modified="2023-09-13" version="1">MGLTPDDHRQILRRLSWASAGLYGLVRCLSSSLSLFDESPLLIHNKFLRWDLIHFAAIADQGYTYEEQWAFLPGAPLFMYISKYLVGFATNNVLACEIFTSVALSLLAFESIQTLYNLSLLHLKSPRLALLASALALLPSSPVTFFFVPYNEPFFTFLSYKGMHACATQQWTKAALFFAVASTFRSNGILLAGFLLWGLLVQPFMTGKRIYISTLIRSTILTAIIFVPFISYQAIAYMIFCLDKPISNPVSWRNKFPPSIYTHVQSKYWNVGFLRYWTVSQVPNFVIAVPPMALIFAYAGHHLRSVSKIFLAEGLRQTPSVKFQNALFITPHALHALLFSSILLFASHTQIVLRLAASMPFTYWAAAWLYIEYPRLGGVWVTWSLMWGLISTILWATFLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRA4</accession>
    <name>A0A9P6JRA4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_926291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRA4"/>
    <dbReference type="OrthoDB" id="3235041at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="789" mass="87604" checksum="847DCAFC340987B9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSU6</accession>
    <name>A0A9P6JSU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_904843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSU6"/>
    <dbReference type="OrthoDB" id="3255035at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="23880" checksum="26C0D22436B1AE27" modified="2023-09-13" version="1">MQKNIIVLVGPTGAGKSHFIDILAGTNWANKKMAQRAVGVRDKEVALSLEGSSTSVVLVDAPGFDDATRPDSEVVRDVVSWLQAQYGNRPHILGVLYFNSIKENRAVGRPQDGLHDFWLMCGLSSRENGERVVFVTTHWDVLGDKGKGDIRRELLQTVVSGVGGIVTDFEGSKASAEEIARGFLRQRPLQLNIDTTRVKPQKLAKPPKVKRFMCSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTI1</accession>
    <name>A0A9P6JTI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription activator of gluconeogenesis ERT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_847787</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTI1"/>
    <dbReference type="OrthoDB" id="5575144at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="284" mass="31498" checksum="1962D840131FE2C7" modified="2023-09-13" version="1">MPSVLNDDKATEAEGDESNDPPHELNPMTMHVYPFPNALAPSHQQPLIRAKRRQVKNACTNCQKACKKCDDARPCLRCVKYGISDECVDSQRKERRRGVKRGPYKKRDGKGSSVDQDDVPDQHQAEAASNMVPIHGEPQYPGPYIPLGYPPGFYQYPPVQHPKPAESPPSSASMPLYATSPSQPYFLAPIPHVQPQMHHVTDVEAAHSYSPQGYYQAAVLTPMAGYHHPHYPIPRHDNPSVHVPDQYPLYGVTVFPKQHLGGQGDMVHAPRNDRAGLVVNGKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTS6</accession>
    <name>A0A9P6JTS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_579373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTS6"/>
    <dbReference type="OrthoDB" id="3053610at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17920" checksum="E1621DD6C2CDF63B" modified="2023-09-13" version="1">MCRRMHSRVGRWTGTPNPYANEPWRHTYSQMAKKTPFLVSTTIVQGSGAALSDKVISARLCWIFHKNKSEITKHFLNITSNYRTNSMINDLITYAINRAIATGVWPRCMLLTVLLVMFPIVHLRRLDVLLCNLFYLQAHRSQPVNTSANSQIPRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU60</accession>
    <name>A0A9P6JU60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_847089</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU60"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF14">
        <property type="entry name" value="AQUAPORIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="304"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="333" mass="35961" checksum="89CFCFE6434B2830" modified="2023-09-13" version="1">MVFLGDIVPRARGLANWERMRNKKQVHWLVECFAEFLGVFFYTYFGAGSTAPWVVGNIIKEPGLSNVLQIGLAYAFGIIFALVVCSATSGGHFSPGITIASVIFKGFPKFKALRYIVAQILGAYLAATLVYFQWKPIIQTAEEVLMAGGPVVFDSINYTPNGLAGIFALYLLPQQKIGYAFLNEFVNCTVLSIIIWACLDPTNLMIPPSSAPFIIGLAYGAAIWGFAAPGVALNTARDLGGRFFAVSIWGSKAWGGNYAAVAALTNIPATLFGGMLYEIFLADSDRVVSKSSLEYLQSLSGHRRTGSQHATKVPVTGDDDNSSHEKGHTSYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVP2</accession>
    <name>A0A9P6JVP2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NEDD8-conjugating enzyme UBC12</fullName>
            <ecNumber evidence="7">2.3.2.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NEDD8-conjugating enzyme Ubc12</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">RUB1-conjugating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin carrier protein 12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_842127</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.34" evidence="7"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVP2"/>
    <dbReference type="OrthoDB" id="10249039at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061654">
        <property type="term" value="F:NEDD8 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="14">
        <location>
            <begin position="23"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="12">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9535667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="20132" checksum="3E89345FF4754A8E" modified="2023-09-13" version="1">MIKIWSMKKNEDAAAKKKPKTSAAQIRVQKDLTELDLPSTMQTHFPDPNDLLNFTLTITPDEGMYKGGAFKFSFAINTNYPHDPPKVKCLQTIYHPNVDLEGNVCLNILREDWKPVLNLNSVMVGLQYLFLEPNADDPLNKEAAIEMSKNRDQFLSNVKSSMNGRNIKGVQYDKVSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWV2</accession>
    <name>A0A9P6JWV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anti-proliferative protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_888224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BTG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWV2"/>
    <dbReference type="OrthoDB" id="19928at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.90">
        <property type="entry name" value="Anti-proliferative protein, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002087">
        <property type="entry name" value="Anti_prolifrtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033332">
        <property type="entry name" value="BTG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036054">
        <property type="entry name" value="BTG-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22978">
        <property type="entry name" value="B-CELL TRANSLOCATION GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22978:SF22">
        <property type="entry name" value="BTG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07742">
        <property type="entry name" value="BTG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160696">
        <property type="entry name" value="BTG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Anti-proliferative protein" evidence="4">
        <location>
            <begin position="88"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9535518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="41004" checksum="887E57347E52B614" modified="2023-09-13" version="1">MKLESQQDPVFLIFFIFSLDCLGLTPLSATFFLSRIAPPATPNKSHILASFSLLPLISYKSPDDTHRSLLLPPFTSIHAMASTSLSTAVAHAIRFLTAKLIGKYPQSTVQRLQASLHESLTAHYAPSWNPADPVRGSGRRCMTLSPSSLAPAPVWTACTAASVQWFDWIAIIGNKEFDLFVDPGCVAVRADNQIITIWSDESLLGAVPKVSSKTFVQQIVEADREEDDELFNLLNDEIAAPTWTTPIHPQFPVSTRSASPLSCVSEHSRCSSRSSNTSSSGFSHYSGDTASSRTSATSGSPSGSPTGQFKQSRRERARQARVYIDTNKKEVTPYDGGKTTVLTGGVMLGGAPKASAGKPKNLAVPSNAMNNSNSWRSVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX53</accession>
    <name>A0A9P6JX53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Casein kinase II subunit alpha</fullName>
            <shortName evidence="10">CK II alpha</shortName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_841873</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX53"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006356">
        <property type="term" value="P:regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="40"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="319"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9535505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="40749" checksum="32B5553D8C1B7372" modified="2023-09-13" version="1">MGRSTTKSVARVYADVNGRLGASWYEYDNLQVQWGSQDHYEIVRKVGRGKYSEVFEGINVVTEEKCIIKVLKPVKKKKIKREIKILQNLAGGPNIVALLDVVRDPTPKIPSLITEYVHNVDFKALYPRFTDHDVRFYMFELLKALDYCHSKGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPKTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSFGCMFASMIFRKEPFFHGHDNYDQLVKITKVLGTDELYAYIDKYHIRLDPQYDELLGRYPRKPWTRFITSENQRYISNEAIDFLDKLLRYDHQERLTAREAQSHPYFEPVRAEAPNANGDGESDSASSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC07</accession>
    <name>A0A9P6BC07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158252">
        <property type="protein sequence ID" value="KAF9521222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC07"/>
    <dbReference type="OrthoDB" id="3202607at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="229" mass="24783" checksum="B19954A9E6EC04A1" modified="2023-09-13" version="1">MKSTVTTGLTDKNGRLLAVATAGPNDLGYKKTVENSSRLFEKIRSDGESSGALRSDNNKRGLFSALHCGLSFGGGQILPKTLDHSSRAQRLVDELLESIDVRRLAGFQSSLLPLYAPNMCGYIEEDLARLYRDNPSLKPNFPGTSYFPACTFNLGPIACTADHVDAMNVPWGWCAITALGIFDHKQGGHLVLYSLGVALELPPGSTVLIPSAIIRHVPGWRSSSLGQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC10</accession>
    <name>A0A9P6BC10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_936177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158229">
        <property type="protein sequence ID" value="KAF9521237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC10"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="26918" checksum="89113DDCF715330F" modified="2023-09-13" version="1" fragment="single">MTQKISPSISIHRLMVPAGGESGRQTESVQVNGWNSTMATPEKEATLNSIDGELYENGSEPPRTPSARTSDISNDRIVITISPGSEGANSSPQASEPSSSMELDFIPIVSSNESSFSPDEEEESAEENFWMGESKRLDQMAGNGVIDRADIDEGHILRNQIIHFTGGIPFESTADIRDGLNGKLSRKRQVYFSKTFGKEFEEFKKRRANALGWSPEKPTLPKDISRVEGDQEPPNDEEPDSNGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E509</accession>
    <name>A0A9P6E509_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic membrane protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_776795</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E509"/>
    <dbReference type="OrthoDB" id="29023at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="16"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="583"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="583"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="624" mass="71400" checksum="83DE403A6A20BC2F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E602</accession>
    <name>A0A9P6E602_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_914953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E602"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="209"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="319" mass="36022" checksum="260667E977486F07" modified="2023-09-13" version="1">MLETTVHIFYTEAALSLNIEQILNEETRVGDVRENVRTQLETKLRSELKVSNIQLLHPSASSVILATDRRGFQFFDDSMSLILPKLMDADGVVNELYAIIPAPAHPGTPAETHAASLASTRPSELQSPIATRMSSIIDGLKGDVANQTSKREKDVKKEREQKAKAKEAAKELEEELMSVKSSQASKVQQVREKTEKSFETRLRAIEMSLVREKDARAELEKSLEKEKDARAEFDKSCAEFEKNLETETDARVELERTSKMRIEQLEQQSEDLENKVDTFQEASKDMNSALMKALLQNASPWLILIARDLMTTPRTTLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E681</accession>
    <name>A0A9P6E681_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase pc-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_910831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E681"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040401021" evidence="10">
        <location>
            <begin position="25"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="508"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="584" mass="66492" checksum="4B2C99497441916B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6D8</accession>
    <name>A0A9P6E6D8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_739731</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6D8"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="24653" checksum="3058D42DCC17B930" modified="2023-09-13" version="1" fragment="single">MANHGYINRDGKNLRAKDVSRGLQHCYNLSPFLAAFLSYGGFLAITGSFWKKIDLYGIGKHNRVEHDASLVHYDTPEGQEFAPIQIDHALVDKLIEDVRPSPQEVEAMKATPSGSDVRCLMNAEDVARARIRRENECRTLKSIQQNTARGEMAIILGVFEVKTASKTGVPVEWMKRWIGEERLPEGWKPTHVQGIFDVIKRNKSILAAIEKLRAEEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E710</accession>
    <name>A0A9P6E710_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E710"/>
    <dbReference type="OrthoDB" id="3222645at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="393" mass="45057" checksum="5222445F69ECC356" modified="2023-09-13" version="1">MGSEDGRLQSAFHKIEELALTIAKRESVIEQREVLLRNYHDELQIMRNENRRLRESNEQLTRERDNFARNLQDATDLSNRRGNELAGAQTFLSKADTISSAELQEKVAALNEEIFQTAAALGEGMVRRRFDVSESTRDERNRKVKGLVGEGMLKILQDHASSDMKDDQPIHPLLVQVAVQVFLTDASNYELGYWDPSDIPFSRRLRDVYIAIQAKEQQPVCGRWRSLTTAHLPPDFDGWKKAVEKNLHRIFSISNWAPRNHEQLEGFYRRLEPMFRSLQEVRTAIWRSVTSEDYRIFYVKPGESFLGDTMQESYGDESINKGDKDRQRVVLGTTSMGLSKAVIKSGFATHELQLVVAPEVVVESTFRAALLTEAKPRSLKRTRNIRPRQDGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7S3</accession>
    <name>A0A9P6E7S3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_640999</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7S3"/>
    <dbReference type="OrthoDB" id="2563021at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040330272" evidence="3">
        <location>
            <begin position="27"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="517" mass="54459" checksum="9EA0FA4D7F0ACF57" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E807</accession>
    <name>A0A9P6E807_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_620424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E807"/>
    <dbReference type="OrthoDB" id="3070202at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="434" mass="46145" checksum="81528F112B05B78C" modified="2023-09-13" version="1">MIGPTSTFYNPEESSLSQGDSHAQYQQWLDAYTTQQPPQSAQSSMHSSYRRDAAEAQQNVFNYIPTQYNPSAAMNQYAPSNAPSAPQASVRGNQAAASGSAAYQPPPDVFAAFYPDMQPMAGSSTSSPDQTHTYTPESTLHSFSNTPEPAYVPQHRTQPSYPSQQHLQPPSRRVPSSHQNQPSNPPLRQTSQYKQQAHTQTRFVTQQQPAGPPQGTGSASSGASASQSNPSSSTTLGPQGLSWNTKASPTMSASSSGGYIHVSQPNPVRSSGGRGADAGPSGSLSTFSMSGGSLSTATPDKVLIAEKAGSKRKRAKKDYVEESGTLSDSDSDDDDGDGLGMTGQISVGMGGLGVVGRGRGRREKGSRLPGACTHCKKLKLGASNVFLYFPSEPMLTIPFCSSTQFPLDYFKCSRLVLTNDAVHRTPPFTQSAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8D3</accession>
    <name>A0A9P6E8D3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM7</name>
        <name evidence="6" type="ORF">CPB83DRAFT_861125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8D3"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="29872" checksum="ACAF24A627B68A4F" modified="2023-09-13" version="1">MLQDEEELGLDTVFVEPPRPPSPIPTSEIYHRDAVKIHSDEAWKAVEIRLVGSHPLWGHHLWNAAKALATYLDQNTGLYQGRNVLELGAGGALPSIVAVNNGASKVVITDYPDRALIENIDYNVVANVPSEKRDHTIVQGYIWGRSVENLLSALPDSTSQAFDLVILSDLIFNHSQHDALLNTCRMALSTSVPDQALGPCVLVFYTHHRPHLAHRDMDFFAKAENKGWKCEKILEKVFPPMFPNDPGEEIVRSTVHGWKLTLERVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8W1</accession>
    <name>A0A9P6E8W1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_819776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8W1"/>
    <dbReference type="OrthoDB" id="5419324at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098636">
        <property type="term" value="C:protein complex involved in cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046871">
        <property type="term" value="F:N-acetylgalactosamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070492">
        <property type="term" value="F:oligosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2080">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052487">
        <property type="entry name" value="Galactose-binding_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037221">
        <property type="entry name" value="H-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019019">
        <property type="entry name" value="H-type_lectin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46938">
        <property type="entry name" value="DISCOIDIN-1 SUBUNIT A-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09458">
        <property type="entry name" value="H_lectin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141086">
        <property type="entry name" value="Agglutinin HPA-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H-type lectin" evidence="2">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="H-type lectin" evidence="2">
        <location>
            <begin position="111"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="H-type lectin" evidence="2">
        <location>
            <begin position="205"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="30614" checksum="31176BC81A3D711D" modified="2023-09-13" version="1">MPTVLEFDSRTVHPPANPATDTKGTVNFPKAFVANPRLPHGFRELDIDKNSNIRAKSTIESLTKNSVECHVSTWSNTTLYSSIETVFALAPANVEFQTGEVMRNANDPASVRVNFARPYPTPPKVVTFFNYLDLDQNHGWRLKITPAEIDEKGFTLKIETWGETVFFGAQAAWIAYPEDRKHIFSASVNVQDVRDWQKPQLQQSKAISFGDVEFWKNPEVFIALNALDINKQANLRLRAYVDGVSKTGLTWHIDGWSDTVLNSAGASIIAFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9H6</accession>
    <name>A0A9P6E9H6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9H6"/>
    <dbReference type="OrthoDB" id="2909885at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52309">
        <property type="entry name" value="N-(deoxy)ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040187190" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19270" checksum="E50C7ADE5B8D5FC3" modified="2023-09-13" version="1">MFTTKYILIAFTLLSLVVAAPIGGRSIEYDQLEVREPQGKLLGAVQLAMKVRHLKPPPNGAVFWSGTKTDAKGKTVSVHADAKKLAKETGGKTIGQALKDQGLSIPNDKNSKQLWRIASKAYAKNAKGEVNAVLGSKVRPESVWNKVEKPTLEKNNNVNKVTEHNAQTGKQTVTKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Y0</accession>
    <name>A0A9P6E9Y0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Y0"/>
    <dbReference type="OrthoDB" id="2607755at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="26155" checksum="9D9B8B089B8FA922" modified="2023-09-13" version="1">MYTPRTFAQVLKSAWRRPRAKLVRVPDNAVKIFEQQPPAWARWALVLVSVDVMVSTSAVDIIWNTWTMPDPELEENGGTKKSPPRDESNKGNIFQVVPPGQVLQPEWKRALSGSFFIVSGFIVAGSILAARARIVRSISYVRATPGVPSSIYLQTASQGMKFGHAYPIRQSVLLPSSQDQMMLEVKEHGKWVLDMRGSKIGNRLASPERTAARSAMLKLWKSVDGSTVASKTPKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Z0</accession>
    <name>A0A9P6E9Z0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_838090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Z0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="18661" checksum="D20EE738CB8EB3F2" modified="2023-09-13" version="1">MITAACLTSGIDLPTLSGYRLRNVVIDWSYLGFFYGTQLLPYKCIELLQLALNLTNCIIEDVNPAGFHSIPNYLKPLGYSTLRYMRLGGTPCQYSMLLIFQKARRVALGDPIPEEDTNKYLKVIESGTQLSIDDLQHSRDLIEIWRKHYTAAKISGRLASQDRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAB5</accession>
    <name>A0A9P6EAB5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flavin-nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_838188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAB5"/>
    <dbReference type="OrthoDB" id="444432at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071">
        <property type="entry name" value="5-NITROIMIDAZOLE ANTIBIOTICS RESISTANCE PROTEIN, NIMA-FAMILY-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071:SF2">
        <property type="entry name" value="FLAVIN-NUCLEOTIDE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30224" checksum="4A681175872E3AC8" modified="2023-09-13" version="1">MAEDSQYTKTFKSTVNRLKDRADYDHETVQTFVNGAPVLHVSFVPKRTDDDPFPTILPMIGGFGSYTAPGSTESSSSALYLHGHISARLFKTSSASEKTPWEEDGLPGLPVCVCATHMDGLVLALTPFKHDVNYRSTVVHGYATLVTDLAEKNFALRLIPENILPNRWENSRVPPTDAEIKVTGILKIDVVDASAKVRAYAVENDKADLVDVDVTGRVWTGTVRAYVRYETPIPGKENAVKDIPKYIDRWIEERNRKGEEYAREITSQLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAH7</accession>
    <name>A0A9P6EAH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="7">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="7">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MDE1</name>
        <name evidence="9" type="ORF">CPB83DRAFT_859316</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="7"/>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAH7"/>
    <dbReference type="OrthoDB" id="191080at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000003">
        <property type="entry name" value="Methylthioribulose-1-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="8">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="234" mass="25971" checksum="16D8427C043A5008" modified="2023-09-13" version="1">MEQNPDSLVISSDPLHPANLIPDLCRSFYQLGWVTGTGGGICIRQGDKVFIAPSGVQKERIEPTHIFVLPYPQPPPSPHTDRVFLRRPTLNLKESACTPLFWNSFHLKNAGSCIHTHSQHAVMATLLWTGPTFTISHQEMIKGIRLGGTGAALSYLDTLELPIIENTPNEEDLKDSMGEAMVKYPNAPGVLVRRHGVYIWGLDWEKAKTQTECLDYLFEIGVKMKLAGLPTSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAU5</accession>
    <name>A0A9P6EAU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_896834</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAU5"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="428" mass="46984" checksum="E6C57CEBD4258C24" modified="2023-09-13" version="1">MQTDDSMYSHHAEQDEHPTFTESTPLISEPPISLQTCGATVAQVQFLTLCLSTFILGWNSSRYFLLFFNLEHYGIGMTEGIRVVQLSQGIGIAAGGLINMPLTPTLGFGKIVLLGSAVQTIACLLQAILPIWPLFVSSYFLQGLGLVLLNTHARAFIAVKRHNDFKMGLLFVIHDVGNMASLSFLSQNHHSEILRKCYLFFSLFLSFLSVVTLVVVFRLRKLDVCLREGGDEPCDSEPDDLSHLDGFTQLIGMKTTHILAAFYSVYTVTRAITTLTILRYESGHLVAFLSVLSSGSTLGYVILIPLNRKVGEINAAYYYTLSAIVALLVAYFVPLVAVQAIAVGWIGIIYSVLSPIVMTYTGRTIPRHLVPGAIGWLTTCSTIFLEAVPPVSNAIFSRYGVSSLLLCAFIGLILMSLALYRLRKTPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAY3</accession>
    <name>A0A9P6EAY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">U3 small nucleolar RNA-associated protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_877003</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the HEATR1/UTP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31183at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012954">
        <property type="entry name" value="BP28_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056473">
        <property type="entry name" value="HEAT_Utp10/HEAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022125">
        <property type="entry name" value="U3snoRNP10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08146">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23243">
        <property type="entry name" value="HEAT_HEATR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12397">
        <property type="entry name" value="U3snoRNP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01036">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BP28 C-terminal" evidence="9">
        <location>
            <begin position="1774"/>
            <end position="1907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2036" mass="225104" checksum="C21129A7D8471AD7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB23</accession>
    <name>A0A9P6EB23_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_737474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB23"/>
    <dbReference type="OrthoDB" id="2688210at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="16138" checksum="40EE8DD853210CBF" modified="2023-09-13" version="1" fragment="single">YVEMWYFTTEACRETALYERSTSDEAFTMSNVDGVMAWKSLNAHKASSKAVPDAALTWNQVSLAKNKFISCIIEKSWPNEHVESLVGLYTGLDSHSIREQEGGDQAVLQYHAEVLREWMDAVTSATGAEPFDISMINQARLQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBD6</accession>
    <name>A0A9P6EBD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBD6"/>
    <dbReference type="OrthoDB" id="2554293at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="914" mass="102623" checksum="B37C2176E5DDA488" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBH0</accession>
    <name>A0A9P6EBH0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_858763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBH0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="42249" checksum="CECB295D0556463B" modified="2023-09-13" version="1">MTRQLLLDLPKELLERILEILHDEGNLLSLGACSLTCHNLSVWSQRLLFRRIKLKAHFQRNVIPLHYFLPIPEGFIFLLRESPHLSEYIKNFELELKMTPTQPTPTIIVNQSSKTRNKGRRAGSSDTTSQNTPAAAVPEPRSPSEEDSPLVQNLFIGLNEFRLTAINDRYYACPWYLSNSGLVKTLGQALAITSSLKVLDVTGVPDFPLSILKGCAIPSLWVSRLVEDEEYTAEEVAESRNTALKSKTACISQRETLGCAPSFLHLGGTSSIYTIELLTNTHGAVNLDNLVTLSIEFSNSFQNTRGIKGSDWPQVANLHLRAPDSSAHRTDSIACELQGPTIHYFALSGSTRYLSRTNLETDCWPLPWFNGLRIVLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBH8</accession>
    <name>A0A9P6EBH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_908471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBH8"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22265">
        <property type="entry name" value="UDM1_RNF168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="76"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="189"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="737"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="737"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="962" mass="110321" checksum="88C97F5E3B9CA2D5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBM5</accession>
    <name>A0A9P6EBM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_795464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBM5"/>
    <dbReference type="OrthoDB" id="3069368at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="20745" checksum="9154A92EF1824B06" modified="2023-09-13" version="1" fragment="single">MSLLQMGNMSLEDDDDIEELESAGENHDYGGGDQDFADAINDGFGDDADDDDLSFDGIYDEDEEQLMPANASFDDLIASPTKEYGPPPMYEVAGPSTYSAYTPQPRGLVAPAMPASASRMGLSNSQASPTQTYYPGIDVCIVCQQRPPYSKNGKSYPTCGMTCANIFKHVLENTDPLPSSVGRGRGGGGGSGFGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBV2</accession>
    <name>A0A9P6EBV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_837579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBV2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="20926" checksum="F242CA5AB16C72F6" modified="2023-09-13" version="1">MSTPQPSPKKRARQDSSLLTCLTELSDEPLSPVDLPPGHLTIMPPCGDPLCRSTICEEAPRVTVHAFLIGSYWETTLEQQVEDTVWTAPYSRGYASLRHCYEFRHLQGGNEEDCQYDIFFPAEDEWKTYVPQQDIAVQLPGFILLRHHHILESRCKDIEDLKKLAKKLYNTRRIRERWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC79</accession>
    <name>A0A9P6EC79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC79"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="53283" checksum="7CEC70797641A4CA" modified="2023-09-13" version="1">MPLSSLLLLPPELLQEIIANLWNQKKALISCSLTHRTLRSLSQKQLFFRISIEEELELEFTNGTPYLVTNALRSRDGKAFQRLLGIAPHFATYVRALQIKVYGDSVLRILDPMHGARAYEQSIEDEIIKPITFFLPSLVNLVSLTIINRGNWRAFTEKYVSQIRPILQHPSLLFLQLRCTHVLYYLEFVCHSLRYLDLEEANPFPTVSSNIIPPREDSTAKTIPLIYLDLLSLHSHRDVNMFQHHVMENSATQVKISRLKKLSIPLSFETNPHPSRFFSSWRILQECADSLQELDLHVPVESVTTLSQFDVQEVSIDLGQLTKLRKLRFSLRVNSDFTPHEFSDHLCCLGKLLWNSSVPLARLEEINIYLNSLAFCQTFLVNDNAWQETAKFMTTMRLVPSLKTLKFFVPTIVCAAILYNSPATLSLRAAGLHVQVLDIPAYKQDYIYSMLDPRLLYFPREHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC96</accession>
    <name>A0A9P6EC96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_770369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC96"/>
    <dbReference type="OrthoDB" id="3342934at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040479746" evidence="1">
        <location>
            <begin position="21"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="170" mass="19077" checksum="F2C854102E61B3A7" modified="2023-09-13" version="1">MFSFATALIALVTITIGVHAEHHNIRVINKCGRGTPYVMAGGKVLLKGEGNYGKDADISSAIAFLDTNGCYPDGLNCMTLETTLVNGRSPGCPTHDPRYPCVSSTDLSLIRGQHRFNVPYKFWYEHGCDGAGHECEFYKYHQRCEWTFYQPNDNQVQVQCPRNNVRRISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED01</accession>
    <name>A0A9P6ED01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED01"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="9096" checksum="A0DE811127090425" modified="2023-09-13" version="1" fragment="single">MVLRRNILSRQNGQDRCRVLLTLLSGLYDILTHATNYSLKHCYQSTARQIYYHKKVMVYRGSTVSEDYTVLSRDVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDQ9</accession>
    <name>A0A9P6EDQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_856586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the calmodulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDQ9"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000006">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000398">
        <property type="entry name" value="Calmodulin-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="4"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="137" mass="15317" checksum="BBCBC0F2122ED938" modified="2023-09-13" version="1">MADQLSEEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMRDTDSEEEIKEAFKVFDKDGNGYISAAELRHVMTNLGEKLTDTEVDEMIREADVDGDGQINYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF36</accession>
    <name>A0A9P6EF36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-processing-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_934270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1931567at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000393">
        <property type="term" value="P:spliceosomal conformational changes to generate catalytic conformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.230:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000002">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1570.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012984">
        <property type="entry name" value="PROCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019581">
        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042516">
        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019582">
        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="JAB1/MPN/MOV34 metalloenzyme" evidence="8">
        <location>
            <begin position="2117"/>
            <end position="2251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2353" mass="271916" checksum="7BD642F99C267768" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF95</accession>
    <name>A0A9P6EF95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF95"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="18795" checksum="1BE35BCC6F7555D5" modified="2023-09-13" version="1">MSTTATKIGCAVENASSEHPMRTSPSSHHQTLLILSRIAPKVFPSCQLSNIQREHQLPSNDSQKRPCLGIARRSGLKGKTQKITRCGVLPPIVKLTRSERSNRTRWTYVHPEELPASVKAIHAQSKQKQKVETQSQEQESKATYVWNCSEPPAVSRKRNTHSDHLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFL3</accession>
    <name>A0A9P6EFL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_814553</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFL3"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040488281" evidence="9">
        <location>
            <begin position="18"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="34"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9528012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="458" mass="49984" checksum="F3F5224FEEBDD907" modified="2023-09-13" version="1">MFKTLLLLGALCNFAISQSTPDDASADGFWAPTKVAAAWYAGWHQSEFPLDKVSWSKYTHMTYAFAETTPSLAGLNETGLTGLPAFVNEAHKHGVKALASIGGWTGSPGFSFNLATPSNRTIFVKAVTNLAVKFKLDGLDFDWEFPNGLGIGCNSINPNDTANFLLFLQELRKDPIGKILFLTAAVGINPWVDANGNPLTDVGGFSKVLNYVAIMNYDVWGSWSDTVGPNAPLDDSCAPPSAQVGSAKSAIKAWKDAKFPASQIVLGIPSYGHSFRVRRQDAYLNGSTTQLALYPPFDKNDPPAGDKWDDAPGGVDICGVKQTQFGGNVDYWGMVDLGYLDSNGKPKDGRPYLFDNCSQTAYSYNPEQEIMISYDDPTSTFAKGKFIKDNGLRGFATWEAGGDYKDLLLNAARKGAGFDNYDFCPSPYFPPPHFGSYPFTTNRWMKKPFTNSQKKLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG85</accession>
    <name>A0A9P6EG85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="14">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_343404</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="14"/>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG85"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000047">
        <property type="entry name" value="Mannosyl-oligosaccharide alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9528343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="535" mass="58288" checksum="34093CD3C8C9F8AB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGA2</accession>
    <name>A0A9P6EGA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_311205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGA2"/>
    <dbReference type="OrthoDB" id="10256743at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="450" mass="49095" checksum="F04624711387C07C" modified="2023-09-13" version="1">MANSGAPILSFPAILRNPGLTSRFAHLHSPSVSGDTATQTPVQTRKRLREQNEGKRWVRRKDNASFVGNPHVVAATKRDYAIPVPQAQSTFPEPLPAYLPRSVKVASSITPVTDVASANAGRFSVSLKGMRRDLRRAGGRAEALVRDVESTLVDWLAQGGTLLHPDKANDAEETMGIPIGTSGTIVEVSRTPLQLVWKIPDDAFARYIVHCCARYHEVVSFIITFWSSPGKGTDDNRLTYLLRPNVTRPDRRVPAGLDTPPITDLDYSSTPDTDIDSDFISERELESDVELDHNTTGRLSSIVESPGVNAASLPLTNDDSWSIIDEGEEPGAEDFDSASEAESGMDASVDILQPQMQALAIAAPAPAPAVQPIVNQTTNAEEDPDKTLTAIRPHALQINSPRRRDWASGRSASSPSRSPGRARRRRRAGQKKRVAFPNASTTSFYNYLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGD7</accession>
    <name>A0A9P6EGD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_766688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGD7"/>
    <dbReference type="OrthoDB" id="3270451at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="304" mass="34138" checksum="F968CE425D9CF4F0" modified="2023-09-13" version="1">MRPGGLHCAYTPEDTICHGSHFYCPAALQATLASLVHGFIFHAYITNISHPETRVLLRRILHFYHRGLIQKAYMTTDQAHLPQLGHSLRHEIDIDEVLNLLSACAIVFFANVLDPRTYTPPGMEEGTIATEKQSQIMEAYDTNDITPDEREGICEARGAVRDIFSWFRQRFTISRPGLENSVDLPSRYLLHLARLILRYKYAAEINEVASAAAFDVGELERQVENTLMLDDSAWDLWLSTCHGAWLDKEMMNRVNVDVRLDEPSTAGASADGALNMETDDLTQEDGEVGDFSVHLGGRCDFPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGI9</accession>
    <name>A0A9P6EGI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGI9"/>
    <dbReference type="OrthoDB" id="2635672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="23"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="589" mass="66734" checksum="D74EF35498690292" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHD9</accession>
    <name>A0A9P6EHD9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHD9"/>
    <dbReference type="OrthoDB" id="3025387at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040343420" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8322" checksum="18F45646F0C478FD" modified="2023-09-13" version="1">MKLNYILFVASQCLLTFALERRQDRKVFTATKVVHALVSQSPFFVDSTTTVVWTQSPSITEPEPTTAPSPTIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI33</accession>
    <name>A0A9P6EI33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase 2C-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_278413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI33"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="404" mass="44562" checksum="FDDF451943CE853E" modified="2023-09-13" version="1">MATRKVTDMGWGQADALWFYTALPEPMLSSELERLAFATSFTDTDVVSFQPCPNPEHSSQDRYVIRDWALPGGNWGFRAIFDGHAGHETADYTASTLPDIIQEKLASVLEKNSEPSPAIIAETLSKAISDFDDSIGEALLKLFPDKLALLDMPDEDVKSIINDGGPNAATVLHCMRGTTVLISVTDPSRKNLWVASLGDCAAILGTKNENGSWKSTILSSSHNGENPLEAEKVKKAHPGEPECVLEDRVLGAIAVTRAVGDYYFKIPALYTHRVFLNAEPGFQSPEKVRSFISRNLTPPYMSGVPDVQHIDLSKSKESETFLILCTDGLIDCYDDHRLRLAEYLGPLWVKIVGRQSGDASKNLALTLLRDALGGDDLDKVSRNITVEMTFRWMDDTTIVVHRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI70</accession>
    <name>A0A9P6EI70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_868975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI70"/>
    <dbReference type="OrthoDB" id="3183767at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1108" mass="127099" checksum="FF976A65320993D4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIA8</accession>
    <name>A0A9P6EIA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_834994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIA8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="19128" checksum="03129BAD8428A8BA" modified="2023-09-13" version="1">METIHNCLGYLYEGSRVRTWSWRSDEQNDGRDFSQGMRRSGLSPVLQAAPQRLVGDQDCRVQSFLGVNRMKMACHFVRGLESAHLWLEKRWQNDIREFSWGMTRPSLVLFSLFANPYISRSPTFIHAVGNNADGHFITLSGREIYKSKKSEPGFVNINIVSGDDQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIF8</accession>
    <name>A0A9P6EIF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIF8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="188" mass="21104" checksum="7B5C3D303DC0E029" modified="2023-09-13" version="1">MTSEIAAQINPRVTDSHLRSPLSRLGDTRKPVSLKGFAHEDEFLELIENIERLGEEFKNLDAEAIRYRWRVRDGLTILYLPQPMASTLSHFIFMLFLQDPSLFSPKGPLEIGGSVRTRLFFGDGYQDPDYSLYSSESTCTTEPVVVFHVALDESRKDVGLMAVDWLAGTESANVAICITVDVDKECSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIF9</accession>
    <name>A0A9P6EIF9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_835139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIF9"/>
    <dbReference type="OrthoDB" id="3235960at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="41"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="421" mass="48169" checksum="E5E193169F65B386" modified="2023-09-13" version="1">MPSSAANSKLHHASDQFKPWRCGDEYRYLPMEKGDDPDEHWETVADHLMQREKSRCDSWKDEVDKLLIFSGLFSAVVAGLLVESHKSLREDPVEALLTKLVAQGANYTISNTSSNYVPSLSVKRVNSLWFLSLVLSLATALIGIVAQQWMREHIRPSPKNTPIRQLPALLNMHAEALDQFQVPKLFTALPLLLITSLIIFLIGLVNFLWSLNHEIAIPASTATRLQTEWFGHAMLWLRQRDLDVLKFHDDKDLENLAEDIRDPGFGLVTPRLYDTIAALRVTKNELSIAKSSKLSHVFQCFQDLTTKSEQLTSHTHDFHIKYILTLLGVNISPRIRGGFGTEVRHFMVDNARLWFLVEDHFGVRVTRPTPYHLELFVRVMRWSLVNIDLEFEIPSSKSPNYRPFPVETLLYFAVVQNSGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIL6</accession>
    <name>A0A9P6EIL6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_811863</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40048at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="8">
        <location>
            <begin position="1"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="9">
        <location>
            <begin position="578"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="699"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="771"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="10">
        <location>
            <begin position="884"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="12">
        <location>
            <begin position="1056"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1135"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1233"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1142"/>
            <end position="1154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9529755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1297" mass="145173" checksum="17021BFDD8200DFA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ86</accession>
    <name>A0A9P6EJ86_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_155112</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ86"/>
    <dbReference type="OrthoDB" id="5784at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070916">
        <property type="term" value="C:inositol phosphoceramide synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006676">
        <property type="term" value="P:mannosyl diphosphorylinositol ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF11">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE CATALYTIC SUBUNIT AUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="188"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="41772" checksum="BD186F56F6F3B64A" modified="2023-09-13" version="1">MAALYHTRIRLSITLVNLRIALLAGYSRLDKSLSPTLTIHRILAHKFVFSDLTYIIHLSLSLFWLSIIPSSPSPIFIPYKLLIPLLYTTTLLLPLTNQFVVPATPVFSWSLTYFSNQYIPDTHRPPVFISLLPTLETVLYGTNISDILTRYTHPFLDILAWIPYGVIHFILPFLIAFFLFLFRARGALRMCATTFGYLNLISVVIQLGIPTSAPWYEVIYGLTPASYTMLGSPGGLARIDELFHSNWYTVGFTHSPLPFGAFPSLHAGNATLAALFVTHFFPSYTEMVWAYCVVLYWATMYLTHHYLVDVVGGGCIATVFFFMFLPNELRGDAALEYPPGYTPGTDTAGFGPSSSSPSFSSILNRAGAGRSKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK61</accession>
    <name>A0A9P6EK61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_763157</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK61"/>
    <dbReference type="OrthoDB" id="336088at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048189">
        <property type="term" value="C:Lid2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036205">
        <property type="term" value="P:histone catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029617">
        <property type="entry name" value="Snt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="7">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="138"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="377"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="621"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="518"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="519"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="889" mass="100467" checksum="7BC50D1513D9BD02" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELF5</accession>
    <name>A0A9P6ELF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6697 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_146625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELF5"/>
    <dbReference type="OrthoDB" id="3176940at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046520">
        <property type="entry name" value="DUF6697"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20411">
        <property type="entry name" value="DUF6697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6697" evidence="2">
        <location>
            <begin position="85"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="45718" checksum="84F17B379ECE2FA0" modified="2023-09-13" version="1">MAGLALTETKDERDDDNILLGPTQAQHTGVDEIETEKLKKMFKSKVKKHEEMRLSDDVFLQRIRPLNILDGFPVTLEREFRDQLVPRKFMSNVYGGSSQMTFPHPRSEKIAEHGYDDFMCLPLDYQPFAPQVPGKPGLFLSTAKGDDIEEPKRVFTRDPSRALRQYMGQYEVKATDSLSREEWLAQPDKVRNTWGREITRQGWGVYVCARIQARKELRRGAQLTQAKLDDVIESERYTRTTPEDVIAAYDSGVERLDVWTMKCIAYEADFQVDLCRKFAAWVPPPKRERKQKALPKRKNGVKQETQAEKASKSEMEKEVDLSAPLQQRSSRGKKRKRAATPESEADEDFEDEEDNEAWATPIYRQETSGVIEILDSDEEEVAVYRFRGTKSRPSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELH8</accession>
    <name>A0A9P6ELH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELH8"/>
    <dbReference type="OrthoDB" id="2131701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23422">
        <property type="entry name" value="beta-trefoil_Ricin_MPL_CNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="19358" checksum="3EA00FAD95327F3F" modified="2023-09-13" version="1">MSIANVNTNTTYIISNVKAGTVIDLSAGDNRTVTGWAKNGGPNQKWVLNWTGNAWNIKNNYTGTYLSIDGSPADGTRLVAAPAPFAWHIWRDANNTNTFRYSLSPVLLLSPEIDVLIESCSIFVPNTNENIDLYGQGISTSGNPITLWYNWTNTHQTWNFTPGQCSIVLDNFNAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELQ0</accession>
    <name>A0A9P6ELQ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELQ0"/>
    <dbReference type="OrthoDB" id="2920847at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040318730" evidence="1">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="121" mass="13004" checksum="6DDA0114341B3D60" modified="2023-09-13" version="1">MQFFSFNTIVLVATLVGSAIATPAPTPAGTAAGESATFISSWNEAGLQRYRFYTNVADKNRFVHAFQNCGGITNNWQAWEENGHGVFDNSEVVGWLGAKVISCGIQTVTGQNCHEISEIGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELQ8</accession>
    <name>A0A9P6ELQ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_849841</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELQ8"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040458078" description="LysM domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="92"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="148"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="26826" checksum="DFB077FE4E3D8990" modified="2023-09-13" version="1">MFKLTVSLLVLALSSSSVLGLAVRQVDLSDSLSASSSALSSTSAVTLTSTIPGDDATVTVTGTPTTVSDSPTSTIDATPVPSSTAAPSGCTKTYTIVEGDTCWGISASQQVPSSALAQLNAASINSECTNLQVGQQLCLEDATSACSTPYTVVDGDYCEKVADANSISLEEFYALNVDIDSVGCSNLFTGSTVCVGSGNSTTPVPTDTVITSALPSTSDFPSPTLTSLPSSSVIGSTSGILSSTITNAPSSSSVPSSTLSSQDPGATTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELW4</accession>
    <name>A0A9P6ELW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_904447</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELW4"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000024">
        <property type="entry name" value="Calcium/proton exchanger, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="178"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="410"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="573" mass="62623" checksum="A79EDC27A4DC2693" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN40</accession>
    <name>A0A9P6EN40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_891184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN40"/>
    <dbReference type="OrthoDB" id="2909885at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52309">
        <property type="entry name" value="N-(deoxy)ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040243807" evidence="2">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="24435" checksum="2E1F370EE73595BF" modified="2023-09-13" version="1">MFTIKYIFLVFAISSSLVAAAPLGDGSARDNIEIREPMKNFAQFARVARTVRRLTPPHNGAVFWSGTKTKPNGKTVSVKADAQKFAHSVGGRTINQALKKKGITIPNNNKYSPRLWNIASKAYAKNARGQAHAVLGGKVRDGSVWKKIEKPTLRKNRRVGKITEHNMQTGQKSVTHQKRITPVNRKKKEVQIRASKQARVIKNKQASIKSKRVTSSRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN41</accession>
    <name>A0A9P6EN41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine aminopeptidase 2</fullName>
            <shortName evidence="9">MAP 2</shortName>
            <shortName evidence="9">MetAP 2</shortName>
            <ecNumber evidence="9">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_848000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="9"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN41"/>
    <dbReference type="OrthoDB" id="7848262at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="12">
        <location>
            <begin position="127"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="437" mass="47986" checksum="9AE7DAA489B233E4" modified="2023-09-13" version="1">MAPTTVASLTGNGISETSPHVAKPLNGSAKVDQVEDDGEGEDDDEAADGVVTGGSAKKKKKKKKPKKRKAEQSNPPRIGLSKLFPSGIYPEGELQHYKDDNSYRITSEEARYLEKQAMEDPETTYNDIRRAAEVHRQARQAARKYIKPGMAMTDIANYIEDSTRALVEENGLESGVGFPTGLSLNHCAAHYTPNAGDTRILQQGDVLKVDIGVHVNGRICDSAFTLNFEPTYDKLIEAVKAATDTGVREAGIDVRLGELAGYIQETMESYEVEVDGKILPVKPIDNLSGHSINKYQIHGGKSVMLVKNKDQTKMEEGDYFAIETFGSTGRGRIVESGECSHYARKVDAPNVPLRLTSAKSLLKSINKNFGTLPFCRRYLDRAGESKYLLALNNLVAQGIVQDYPPLCDQLGSMTAQFEHTILLRPTVKEVVSRGDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENF0</accession>
    <name>A0A9P6ENF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sel1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_808501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENF0"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="491"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="526" mass="58258" checksum="48D41B5ED5F2D3D8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENZ0</accession>
    <name>A0A9P6ENZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_740334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENZ0"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="35137" checksum="F1D5BF57B57A9AA1" modified="2023-09-13" version="1" fragment="single">SLGLALMPFVSAVVHDIQVGAGGKLVYSPEAIAASPGDQVVFHFNPKNHTVTQSAFANPCGRKDGGFNSGFQPVPANQTDNLPTYTVQVNDTNPIWVYCAQAANTAATHCGAGMVFAINCGLDGAPNSFTNFKNAALAIGTSLKANAPSSTAAAQAYTTAAYGGYTIPVAPTPVPVTVPVTLGTETWTTTYASYPNSPAPTPASAEGQVIKVVVGGPNGKLTFDPSRVSASPRDTIVFEFHEKNHTVTQSAFDDPCRPLKASGTASAGFDSGFQASDGTTLPTWNYTVKDTAPVWAYCRQGNHCGAGMVFAINSDESSPRSFQAFQDVAKGLNGTAAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP48</accession>
    <name>A0A9P6EP48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_678834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP48"/>
    <dbReference type="OrthoDB" id="3040699at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30216" checksum="CC2996C79D958643" modified="2023-09-13" version="1">MTTGVMQMRLTDPTCSPAVREEGTLKSGESSPLLHLMKSSNFIPAESKMSHSTAAQVSQQASLDLWELPPYNEAESLFGPDLRILSVKTGRKEHAYISFELHLSEADFSGLKYWKESKSANSLKDIQTSFCISIACYRREDLLDDLNLLSSRVSVLSSSWPQHPASSSLLIKTLTSELSVPLSPPIYLTPDKLVDISPWLHLGGNQFGILQQGMDDYAFVILLHRPTRKQLQQVSAARLNDLAWQHFLDGFSAPIEYIPLRSLTLTANPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP94</accession>
    <name>A0A9P6EP94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_847054</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP94"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF74">
        <property type="entry name" value="AGR407CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="82"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="111"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="346"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="597" mass="63399" checksum="BB90647B4F3EBA6A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPC2</accession>
    <name>A0A9P6EPC2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_784493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPC2"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="576" mass="62846" checksum="CB4C322DBDF9C624" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQY5</accession>
    <name>A0A9P6EQY5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_749743</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQY5"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="84" mass="8628" checksum="FEE580B2EB51F30D" modified="2023-09-13" version="1" fragment="single">NSCNTGPVQCCNDVHQSNSNTANLIHQVFGINIPVTGNVGTQCSPITAVGVGSGAQCSSQPVCCENNHYEGLIVVGCTPININI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES53</accession>
    <name>A0A9P6ES53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_844217</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES53"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03754">
        <property type="entry name" value="proteasome_alpha_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000026">
        <property type="entry name" value="Proteasome subunit alpha type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034642">
        <property type="entry name" value="Proteasome_subunit_alpha6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="263" mass="29197" checksum="0737DBDE604F6D0F" modified="2023-09-13" version="1">MSRTSYDRYLTIFSPEGRLYQVEYAFKAISGSGHTAVSVRGKDTAVVITQRKIPDKLLDASTVTHLFSITPTIGCVMTGLLADARHQVTRARGEAVEFRYKYGYEITPDALARRMANINQVYTQRAAMRPLGISMILIGIDPEFGPQVFKLDPAGYFVGFHATAAGQKQQEAMNHLEKKWKKLDNGRGGDDATKAGQSLSRNEVIELAIEAMSTVHATDYKPGELEIGIVSTAEDENEKLRGQWRILGEAEIEEHLLAYAEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES97</accession>
    <name>A0A9P6ES97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Galactose mutarotase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_844956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES97"/>
    <dbReference type="OrthoDB" id="274691at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="430" mass="46968" checksum="ED9F1E35879374B3" modified="2023-09-13" version="1">MAEFKPVKLSSPGHSDDGIAVEVLPYGLTIHKLLVQTDGRIHDIVIGPENPTDHVAQKYTNSIVGRYVNRVPVGTHSFERNGVRGDITALPNESPLVSLHGGPKGFDAVPWTLLTEKDALQLFSKAEAARIRAQPESSFAVFRLESPSGDQGYPGSLIVEVLVALISPDHQQKISENTPQNEVDNRVGSLALVYRAKLREANAVTPVNLTQHWGFNLEASLNKGPETLSVKHHTLTIQADKIAELDSDSLFTGRHVPLTPAHTHQAKPIGKDFPEKGYDDYYLFKDDLQSAVPTRIPLSSFNDDSDFVQDLLRSSDNPERGLRGPPAIELASERSGLKLLFDTNQRGTMFYSNALAKSSAGARKKIHGGSGVSGSGDAYDPHTAVFLELHHPLAAFLHTNEKAGEDTLLTSEELYHNYVRVDITSKQSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESY0</accession>
    <name>A0A9P6ESY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cullin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_842711</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESY0"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000161">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000011">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000026">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000012">
        <property type="entry name" value="Cullin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000029">
        <property type="entry name" value="Cullin homolog 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1030.10:FF:000002">
        <property type="entry name" value="cullin homolog 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1030.10">
        <property type="entry name" value="Ring Box Chain A, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="9">
        <location>
            <begin position="415"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9534666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="764" mass="88113" checksum="0F129CD5164150A9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETB7</accession>
    <name>A0A9P6ETB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sac2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_842942</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETB7"/>
    <dbReference type="OrthoDB" id="19482at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="7">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="371"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="587" mass="65982" checksum="257B97B31F2C5CA5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETQ3</accession>
    <name>A0A9P6ETQ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_879639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETQ3"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="341" mass="38507" checksum="7EBE7E33DB8FB393" modified="2023-09-13" version="1">MSFFNQDISLIEPCFPLDSFVPYTDCWTNDPTLNNLDAFDYYQHFPNTSGQYVYSHPTNLFDEYGYTSSTTSDSDSSYDHEETTMSEDMEAVAQPREWADSKADNVSRIEFQFEISNKAICNSSDALSAHSTVEYDSPLPIRVPHLVNSPSSSDYGDSDDSFSDYRPSPSPEPVFRKASRSRPYPRQQSSGSSSPQPMTLSPIKNRRGSRRNARSPASRNIQAAGEEAALLEQHLESNRNAQNALVCPHPGCRYHQANGRLPDFRRHLRTHLRKAGQHRCKGVSYLDFLQFPEQFPGISEDALPYIVDGCAGMWIGGCNKTFSRADALKRHYDKQTCVRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETQ9</accession>
    <name>A0A9P6ETQ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_843074</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETQ9"/>
    <dbReference type="OrthoDB" id="10261904at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17955">
        <property type="entry name" value="DEADc_DDX49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="158"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="394"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9534869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="588" mass="65312" checksum="4A91CB695B72D362" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETS5</accession>
    <name>A0A9P6ETS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_923985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETS5"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="452" mass="51190" checksum="80F53F81A2A17BE6" modified="2023-09-13" version="1">MLAPRPAIPLELIEVVIECLANEENLDAVQECCVANKQLVHACRKHLFAKIKVLQEPSGLAKKLSQWPDFVTPHPICRFQRLLERNSSISSYVRELEISSMEEYDFRDNLVALQYLTTVQVFTFGFSDGNRMTAEWLWATLPAEVENSLVKFVQQNPLVSVSLFGIRGLPTAFLRVFPYLESLTFLNVKLFMSSESATSPTAPVKQRKLYLQENLSSLAVQLNLQPVLDLRDLTDLSLNIGFRDNPQPALSLISLPQWLKTLSLVADASWPDFTCRDNVLTRLGPTCLTTLKKIKLEFEVSSTHHFPPYGGLIDELQAISGLNVLEEIYISTRVNFDSEYDMDPELWNQLDTVLCSGFPNFRTLSINLSVGVFAPQEVTQGTQEKLDKCFAEILQWSKKNLNFTASVEATDEGVVADLLELAYDYMTYEIDNCWPRAPFKKIGMAIDRDISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETX1</accession>
    <name>A0A9P6ETX1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">5'-3' exoribonuclease</fullName>
            <ecNumber evidence="15">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_843214</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Possesses 5'-&gt;3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="15"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETX1"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000003">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000005">
        <property type="entry name" value="5'-3' exoribonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 15" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="16" id="KW-0862">Zinc</keyword>
    <keyword evidence="16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="18">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="408"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="533"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="964"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1147"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="977"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="993"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="1014"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1055"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="1073"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1096"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="1147"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1165"/>
            <end position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR037239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9535221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1192" mass="130940" checksum="A876CFB88EB9C495" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUY3</accession>
    <name>A0A9P6EUY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_841565</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUY3"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="16653" checksum="929A3931EE7C346B" modified="2023-09-13" version="1">MSSTFFTWLRSPAAREYFFSTHFWGPVANWGLPLAALADFKKDEEFISGTMTSTLALYSMVFMRFAWRVQPRNYLLFACHATNATAQTVNDIRFYNYWYRGGREERQAQEGKILPAVESKVLQAVKEAKEAKEEVKETIKKTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV37</accession>
    <name>A0A9P6EV37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV37"/>
    <dbReference type="OrthoDB" id="4540223at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="92" mass="10077" checksum="8989D6E1955A23D4" modified="2023-09-13" version="1">MWFKGDQVVDDYIVNHLESTWDPKKTLRMSIINGKQWGNVQLVIPPGLLNSKGGGMGLAASCKKKLGDLPGAVVNYGDWQINTKGSKTDPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIW7</accession>
    <name>A0A9P6JIW7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIW7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040110779" evidence="1">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9347" checksum="3F0D991CE04A2736" modified="2023-09-13" version="1">MVYHGARPPSTRRNPAGLAIWVLTLPTGSGTTVSQSQPLGFVYPTWTRTTTGQLSFDKETLEVIDDKHITNLPGQSKDVRARCGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ09</accession>
    <name>A0A9P6JJ09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_887354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ09"/>
    <dbReference type="OrthoDB" id="3199068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30749" checksum="7F331F8CC990AFEC" modified="2023-09-13" version="1">MDLDSDPVMVPSDGAAIRERHQKYYFELVLFEVEKTLFNVPKSGFLRSNPKFFDQFGATGTSLPSDEGQSTPIELKDVTAQAFEGLLLVLYPIDGTASTYEEWLGALELATLWDFPNIRTKAIEAMSILNESNSRSTMEIVVLSKKYKIKSWLREAYIKLVQQKHVDLEELLKVLDCETVMRLFAARSYILQTYTPAKLQNLCNSCRSGRGYTHCSNGCYKAGGFCDLDCPNSGRYQECTNVCTNRPISGGLDNLPKVEAEVDKIFNAEFSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ11</accession>
    <name>A0A9P6JJ11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ11"/>
    <dbReference type="OrthoDB" id="4584900at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040133918" evidence="1">
        <location>
            <begin position="22"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="279" mass="29453" checksum="8718EED06B5D9D4C" modified="2023-09-13" version="1">MLKVLQLVFVILIVFYPTSLASPNSFNIDNKKPRNVAVSPSPESSSAIGSKQLTNAVRLARGLPPRAPQFRRFLPGIRPRTSNASAPDPGPATVSGVIQITRFDDDGEFVGYVSRELHAIPGSAANSQTLAITTKLSTALTAKLTPTDSLFEITALDGLNPSYPFLGGAATSATSVDLVSGSPNFVYITGSSSTDVGPPTVVGNSYGSVPSESPIWNYDKSTREITATWINADKTSAPTYLSALPMANSTSLVLIGDPAAFNATYPGSYQLKFTLTTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ18</accession>
    <name>A0A9P6JJ18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157944">
        <property type="protein sequence ID" value="KAF9522469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ18"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="91" mass="10396" checksum="2F2AC4E822814101" modified="2023-09-13" version="1">MLLVYNLTQALRKIVFKLHALNIRENGLLWSVRYMAQVPPTKAPSLSALLGDVIHRPGHSSVSLKHYDDTERLELASWRSRRCLQAGAREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKI4</accession>
    <name>A0A9P6JKI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_949095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKI4"/>
    <dbReference type="OrthoDB" id="5392263at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="507"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="542" mass="60502" checksum="560C35F72A21E171" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKP8</accession>
    <name>A0A9P6JKP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_734729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKP8"/>
    <dbReference type="OrthoDB" id="2142724at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="56" mass="6089" checksum="BBE61287D35929BA" modified="2023-09-13" version="1" fragment="single">ILPALSLDAVLHLNILDRSYTTAAFFNESIDGLYNMNPSPGPNSVIVMDNTSIHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKY5</accession>
    <name>A0A9P6JKY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_898058</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05274">
        <property type="entry name" value="KR_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="606"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="710"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1623"/>
            <end position="1905"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2454"/>
            <end position="2529"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1623"/>
            <end position="1745"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1757"/>
            <end position="1905"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="1665"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2537" mass="278118" checksum="682F0C074B42BFEA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLM4</accession>
    <name>A0A9P6JLM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_859646</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLM4"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="16"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="562" mass="62575" checksum="665B262766B27D47" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLX0</accession>
    <name>A0A9P6JLX0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyranose dehydrogenase (acceptor)</fullName>
            <ecNumber evidence="3">1.1.99.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_896749</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O(2) as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a pyranoside + acceptor = a pyranosid-3,4-diulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a pyranoside + acceptor = a pyranosid-3-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>pyranose + acceptor = pyranos-2,3-diulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>pyranose + acceptor = pyranos-2-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>pyranose + acceptor = pyranos-3-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.29" evidence="3"/>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLX0"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033718">
        <property type="term" value="F:pyranose dehydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF1">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040503782" description="pyranose dehydrogenase (acceptor)" evidence="13">
        <location>
            <begin position="19"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="14">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="15">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9525707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="769" mass="82203" checksum="4839DA1DE195F3B6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM29</accession>
    <name>A0A9P6JM29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4 13">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_858769</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="4 13"/>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM29"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.870:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.9.10:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00978">
        <property type="entry name" value="FAD_G3PDH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="15">
        <location>
            <begin position="84"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="16">
        <location>
            <begin position="473"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9525872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="779" mass="85788" checksum="2BB41F884244D729" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMK3</accession>
    <name>A0A9P6JMK3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_858907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMK3"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="408"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="696" mass="77434" checksum="42F591B41839D4A0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMQ7</accession>
    <name>A0A9P6JMQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Temperature dependent protein affecting M2 dsRNA replication</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_507544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMQ7"/>
    <dbReference type="OrthoDB" id="17262at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022039">
        <property type="entry name" value="MKT1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12246">
        <property type="entry name" value="MKT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Post-transcriptional regulator MKT1 C-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="233" mass="26281" checksum="35F80EA1B58ED664" modified="2023-09-13" version="1">MYGAIRSARVNDKFQDPLYLFLELVRAGVMHGHLWSGRAFSGGPSFGTDQEKSCMLLVMRVLSIVPLNFKAQPWSAPLSRELLVFNSFVRSLTRALRTLLEVSTLNMLIRNDARKARDDLLDITLSLPFQTEVNTGFGVLAKVYLDALTHINGGQRVTDKNAQGVDVKKEMALELCEETFPGVKNPKQEVERGFRFWDLALTAMRQLHSEGAVLRELIDQFEAAETWLAPMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN41</accession>
    <name>A0A9P6JN41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN41"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="209" mass="22891" checksum="DF23FB9C3BE0EF5C" modified="2023-09-13" version="1">MPLAPPLPLVFPCVNFKDSTRQLYHRLRLLFSVHSSTSQATVEGPAFSLEEPTSTSRSKDSYSQVYHASNSLALQSRYTEQRTSAIHFAPLSPSVSVLSIDSNPFALEVVEHLGFIKQSGSIRPLPNGFNCTTHSSLETFTAAELTDETTEGHPIADLPGSLSPAGRTVLDSGVCLSPILPWDDLDSSIQPLSDILPPRYDKIIRKDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNI6</accession>
    <name>A0A9P6JNI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNI6"/>
    <dbReference type="OrthoDB" id="548295at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="888" mass="100138" checksum="FF19B253BCFC7EB9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNM2</accession>
    <name>A0A9P6JNM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_855940</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNM2"/>
    <dbReference type="OrthoDB" id="1551503at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="12">
        <location>
            <begin position="17"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9527522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="10213" checksum="D48A15632A4AA64C" modified="2023-09-13" version="1">MDFSNFNGAEQAHMTKVIEKRQMQDFLRLYSNLVEKCFNTCCNDFTSKALSSKEETCIMNCTEKFIKHSERVGARFAEQNAENMNQGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNW9</accession>
    <name>A0A9P6JNW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNW9"/>
    <dbReference type="OrthoDB" id="3066754at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="711" mass="76519" checksum="FFF6FD4B567C6363" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP67</accession>
    <name>A0A9P6JP67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP67"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17688" checksum="CC60774D4EA7540C" modified="2023-09-13" version="1" fragment="single">MPYCQSYRRAASFGQVSSQAQPERPPIISQRSPHSFSHDYNQHIEEFSEPYYTSRGEPQSLLHAQHFGPAMNGKAMGPRRMDSAQIVAYEPPTIRATRSEGIRRTSTLQICKACLAAPALPKRNESRTVHFKDEKQQSPGTRFLTKLLSIRTRNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPS8</accession>
    <name>A0A9P6JPS8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPS8"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="31715" checksum="CB9AE42CCD7D5F34" modified="2023-09-13" version="1">MATTDPSAVKAFLTFNTPPPKGERAFVNINADSSTAEKQTNAPREPKEVTVENVRGKEDTVSLNSTGFQYFKAPAKYKTFTNDEEIQKEYYPESAELIKKLTGASKVVLFDHTVRRRRPGEADDGPSRRQPVGFVHVDQTTQAAIARVHRHLPADEAPKLLEKRFQLINLWRPILHAAFDQPLALCDYRSVEPEKDTFPLALVYPDREGEIMGVNYSEKMKWRYLRGMTPDEIVLIKCFDSLQDGKTAVFTPHTGFKDPSTPVDAPLRESIEVRALVFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQT3</accession>
    <name>A0A9P6JQT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQT3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040264703" evidence="2">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="13377" checksum="E6995D934E46A021" modified="2023-09-13" version="1">MKTTAFFAVLLSAVTVVSALPADGAKPPVSHSGPVPSFTAPPKPSFSLPPKPSFSFVPPPKPSFSGGPKPSFSFKPPPKPSFSFVPPPKPSVPHPPKPSFSFVPPPKPTFSLPPKPSFSKPPKPTTSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQT6</accession>
    <name>A0A9P6JQT6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_905956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQT6"/>
    <dbReference type="OrthoDB" id="2852053at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="309" mass="34926" checksum="3DA8121A63A59D27" modified="2023-09-13" version="1">MSPYPFAEAKSFMELMGNNINLPSRDTWFSVQQHPQLIDISRLILVSPVLNDAVSAASQNGPMVGGTEDNPLVMPDSVQFPVFRDFCGWFLLLNGVLDHELDLSQLENILEMSHYWSVDIGQAFAADRLASSPDLSPSYRMMLARRYHIHHWVDALTVELFNLPYSEITGLEVVQCSTDVWAVINKARDGYRDALNVLAVVPPSLPKETNHSFMPYCPNHKACIREWELVWYSKIGRRLLIKDKDHLEPIGVMEHVTSLSFPQMGRECRRDALELLQSNPNVFNIKHNVEQAAIDGVRAALGLPILSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR18</accession>
    <name>A0A9P6JR18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6830 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_926844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR18"/>
    <dbReference type="OrthoDB" id="3232941at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6830" evidence="1">
        <location>
            <begin position="175"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="330" mass="37661" checksum="7B7B842713AD1B9F" modified="2023-09-13" version="1" fragment="single">LLTEKELDARVKALPPSFGVRHFSNGFSVLSQISGPERKEMTKILLGCLVGEVSEGILIAIRALLDFIYLAQYKAHDDETLGYMENALQRFHTHKKYLIEAKLHKDLAIPKFHSLLHYIHAIKEFGTTDNYNTELFERFHIDYAKEGYRASNKRDIFPQMVAWLSRREKISMFDNYLDFKDNLASQQSPTTATSNSLEPSIPSQISIAKHPSFPHRPITTIQKNHASPLFSDHLKDFLNAFLSHPTSNAQSHSFDLPFNHLDIWSQFKFDKHALQSDDIEAETDTVKAIPRSKDDPSGRFDTVVALWDPTAEETGTTGKLRFLDFKAVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRJ7</accession>
    <name>A0A9P6JRJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_851628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRJ7"/>
    <dbReference type="OrthoDB" id="3234968at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040199597" evidence="3">
        <location>
            <begin position="32"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="422" mass="45467" checksum="CA47045AA11B509D" modified="2023-09-13" version="1">MTTFINWSTSSTLRFLLLIFITCHSFSLSHALLNITIDDTSSYIHFEPQESWTRIIDQSGTLDAGGSHMITDDPNAFALVTIAFTSVYVLAPSWPYAVSSQVTVGDATLLVDLQDHTVRDLGVGSSAPPTVQSHPVARIVNSNYSTQTIRISVPPGGKFAVFDMLIIQIPDNQLIPDGLATTSVVSGSTATAISVATSDPSTTSSTASGTTTPKLKHAADGDGSETPSSRQDYGLLIAIAVMVPTILILSGLLFWKCYTLRKRKRSRMKHLIDIDSSHTLNSAKEFPHYTPDPQESPYVPVSSTPASPWNGAPSPHDNPRIYLSPQPQPSPQPSWSAGHEGMPSIAHPYARDRIPNSKPIKQEKTANLQVLNPPRFTMLSGVMTLSSPPSYVSALDGVASSSRTFSDIPPVPPLPALIRQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS12</accession>
    <name>A0A9P6JS12_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ASX DEUBAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_811365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS12"/>
    <dbReference type="OrthoDB" id="2289918at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028020">
        <property type="entry name" value="ASX_DEUBAD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13919">
        <property type="entry name" value="ASXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASX DEUBAD" evidence="1">
        <location>
            <begin position="38"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="41771" checksum="1869AC80A0BE793D" modified="2023-09-13" version="1">MDRPRRVVKQANRGPVQIATIPTSSRPVVKRNVPAPVDPEKQIQALLQSSKSDLVNLDMAGIINSRTWAMLSDDAKDRLKILLPQSAFIGFQERLPEDHPISATVKQMAAVKSGDANTQVIGGEVAGPSNRAVALHEELDHGFFTDPHLLSAMRTFQDHLYLNWFSSAHQEKVKQFVEGVTNGALSAPKKDEVWERDNIVSGTDITLLSVPGSTPSAKARGAAEVKLSKLVKNKVVRVGDVLAYKRSFASSVVIEKDCIIESTGPDGIVVSLAPERTKFLPPFLLSDPPTPSPPNTPKALHPQSATITSPSMLETLLLDIEGQLEKSRRPNGNAWKYFSIWRWRKTGFSDCSSADADKRGGRENHGTLFYLRGSFYNEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT50</accession>
    <name>A0A9P6JT50_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Putative peroxiredoxin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thioredoxin reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_874701</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer; disulfide-linked, upon oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT50"/>
    <dbReference type="OrthoDB" id="195498at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="4"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="10">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00063543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00079296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="170" mass="18160" checksum="095B7C62CCFF269B" modified="2023-09-13" version="1">MASLKVGDTVPEGTFKYVPYTPELENGLACGVPIALKTSEWKGKKVVLFAVPGAFTPTCHVNHLPPYLEKYEEFKAKGVDVIAVVAANDPFVMSGWARVEGLKDKIIALNDTDAQWSKSIGQTLDLSGLGLGTRTGRYALILDDLVVKYFGVEPAPGVTVSGAEAVLAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTI0</accession>
    <name>A0A9P6JTI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_732373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTI0"/>
    <dbReference type="OrthoDB" id="2400485at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20212" checksum="5A31EEFC59F45956" modified="2023-09-13" version="1" fragment="single">TTMTSQVDSSLNSAGLKPEESKALQDRSAQPHEQPVITAIKEMYSCKPTATTFNVYATDAVFHDPIGIAPGRESVRNQFIALAKLFPRADIPKFRILENPPTVPPNTILIDQDVAYFRDANASAPTKTVNSLLTLKVDDTNKVISHNEEWDHSKTTTGEDGFFGMLNEHRKKITAKLTNVMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUV7</accession>
    <name>A0A9P6JUV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chromate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_755312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUV7"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567:SF3">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="535" mass="57802" checksum="A9E0452305B5104D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUZ1</accession>
    <name>A0A9P6JUZ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_844863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUZ1"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="14"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="435" mass="48568" checksum="2CEE7F076B841F68" modified="2023-09-13" version="1">MPQDCLEFKQFKAWVNIDGEKTPCYAVEVDKKERTVSGWIASEKGKEFWVGINKMDKSRCAVRVTCYVDTLNVGRNFFKKSELAWVKFDSLMLSKKAERPFVFSSVNLTDDDAYLEPSLDEKKKGAIGELTFKVHRVTRLITKRTKRNRDDTSEEDDSEEEIKLEKVHERSKAGITMQHQAGLGEKRLKAVNSDDDVIEDRYYDTSVYSEIKELIATFTFRYRSLEVLQASGIAPRERKDDELPTNDGPKEVIVINEDGATEEPANPQPAIIDPEPDVPARHESIEPQQQSPDGHPLSPVSPPAVSGLEESTSGTLLSSQHDISAGGRQSLTPPLNSSTSTQSSELFNPATSVNPLKRTASEVDTAEEISEDKIKTDPDMDGVEARKIAILAELAQIERLQEMQRAAGPSAQKRVKREPSAPVMFFKPGEVIDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV79</accession>
    <name>A0A9P6JV79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_832137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV79"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="9"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="300" mass="33967" checksum="56B628B2ACC8E601" modified="2023-09-13" version="1">MLGNQENIIAIMGPSGSGKSRIIDTLAHTNWSGPGLANVTQKIQSVKTTLKSRNGKGVQVTLVDTPGFGDTHKSDLQILEMIADWLEQNYRKGVCLTGIIYLARITDNRITGDSFRCMKMFGKLCGGAEQLAKRVAFVTTMWDKIQHNVGTGREMALRDVLRPMLDRGARVLRSNNTRTSNQQIVLDLIDLTASQPHPVLMQEEMVDQARPLIETEAAQMLFDQFQILLSKHKATLKDLEEIARRSNDSNLREDLELERQKIEKELNDTFAEAKKLKLSWAQRLLAFFRKSVRFFEFDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVV4</accession>
    <name>A0A9P6JVV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NCS2</name>
        <name evidence="3" type="synonym">CTU2</name>
        <name evidence="4" type="ORF">CPB83DRAFT_902530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTU2/NCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVV4"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03054">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="523" mass="57337" checksum="58333DC11166DB80" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW43</accession>
    <name>A0A9P6JW43_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">INO80 complex subunit F domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_209605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW43"/>
    <dbReference type="OrthoDB" id="10070927at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056513">
        <property type="entry name" value="INO80F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24245">
        <property type="entry name" value="INO80F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit F" evidence="5">
        <location>
            <begin position="77"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="126"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="488"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="533"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="701" mass="76564" checksum="BAE0DDB4AD618B48" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW79</accession>
    <name>A0A9P6JW79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW79"/>
    <dbReference type="OrthoDB" id="3064491at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="485" mass="52917" checksum="B7C737546586C966" modified="2023-09-13" version="1">MKPIAFLRNTWKKFDKSSESRDSPSPSGTSRATTRSPASFSSSLRVKVDRVTIEHIGRSSPVPVPPPKDNVSPFHATAPRDRPNHRQLRRVASVSSDTVSLADYPTYLQDPFNSISPSSIPSPSRPSPSPLSPNKTTPLNANGNTFRSNVNDASVTPPHIRPRKTSIQSLRQRHLRLPALDFLPLLELECPHTKDHNASTCSSCSTNAAWPMYGHRDEHSDQNADQSPKRTSPAAIPCSPTDCVFPTAVLSPTRSRGGFYQTLAGSSPHLPYNHNASTHSPQLDTSTHNQLRKDDVDTFPLSLFPSPPPLTIRKKRPSPLVIRPVESMSTLSSTDSTPVGTPTTPRFGPFIQPDSPSGSISSSSSLSRKTSFARSIAIFSPPPTSPPTSPLPDLPGQRSSHQNHSLKTANSCINLRQVSSPRRRLTSSEPIRHGGVPRTIQSPTRQQFSPHSTEMNPGKDIVQFRPRAPSAPAQVDAQVQWGYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWC9</accession>
    <name>A0A9P6JWC9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome oxidase assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_755366</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2</text>
            <dbReference type="Rhea" id="RHEA:63388"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:61715"/>
            <dbReference type="EC" id="1.17.99.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:63389"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWC9"/>
    <dbReference type="OrthoDB" id="1726137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120547">
        <property type="term" value="F:heme A synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01665">
        <property type="entry name" value="HemeA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023754">
        <property type="entry name" value="HemeA_Synthase_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="412" mass="45249" checksum="2852424064210903" modified="2023-09-13" version="1">MEVKTVKEDLPLLTPPAVSRWLLASSALVLGIIVVGGVTRLTESGLSITEWRPITGVLPPLSREEWMLEFEKYKATPEFKLMNHSISLEDFKSIFYMEWGHRVLGRLIGLVFVGPLAYFAIRKKIPKSLSLRLTGLATLIGAQGALGWYMVKSGLEDSLMETPGAIPRVSQYRLAAHLGMAFLLYLGMFGTGMAVIKDWKFAHGAPWSGFKGNGSVAEIQSILNNPLVKSFKKQSWVVTGLVLLTALSGAFVAGLDAGLLYNEFPLMGGRLAPPSDELFSPNYAKNPDKSDLWWRNIFENPTTVQFDHRVLATTTYFSTAYLYARTFHPALRAALPPLARMAVMAAFAMANVQVALGITTLLYLVPIPLAAAHQAGSVMLLSAMTHVLITLRRPGAAASAWRKHWSNYRGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWY4</accession>
    <name>A0A9P6JWY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:flavin oxidoreductase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_842078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWY4"/>
    <dbReference type="OrthoDB" id="72788at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="350" mass="38590" checksum="AAAEA2D01A5A989B" modified="2023-09-13" version="1">MCQYSSDNGHATDWHLIHLGGFATRGVAAVTVEATAVVPEGRISPEDAGLWTDTQIEPLKHIVNFSHAQTTKIGIQLAHAGRKASTRAPWVQRQISKGGSSIATKEEGGWPDNVYAPSAIKFSPTYPEPKAMTDQQIHELEDAFLAAVERAKKAGFDFIEIHGAHGYLLHNFLSPLSNIRDDKWGGQALENRLRLTLQLVKRVREAWSGPLFVRLSATDWAEGLEKDENGHWKQWGIEQTIILVGKLKELGVDLIDVSSGGNWVEQQIPLGPGYQVPFAEAVKKAHPDIAIGAVGLIQEPVQANEIIKNKQADIVFLARQLLGNPHWALHAAKELGFKPKAANQYERAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E372</accession>
    <name>A0A9P6E372_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_841085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158005">
        <property type="protein sequence ID" value="KAF9521670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E372"/>
    <dbReference type="OrthoDB" id="2970937at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="594" mass="67456" checksum="D1087CA7CE628505" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3D8</accession>
    <name>A0A9P6E3D8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5077 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_872150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157989">
        <property type="protein sequence ID" value="KAF9521781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3D8"/>
    <dbReference type="OrthoDB" id="6338748at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021862">
        <property type="entry name" value="DUF3472"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031712">
        <property type="entry name" value="DUF5077"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11958">
        <property type="entry name" value="DUF3472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16871">
        <property type="entry name" value="DUF5077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5077" evidence="1">
        <location>
            <begin position="6"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="37714" checksum="AF3AF861A04DC4BE" modified="2023-09-13" version="1">MSTKTVALSGNGFLTTVPAGATEIINDNGLANWNNPNTICSAYFRMSSAGSVTLGLNAYLAGSNSSTIKVTINGTAFTIQLAGTTAKTYPVGTVNVTAPGYVKVDIQGATKDGGYFGDVSGLSVTTTSALTYANDPANYYWSRRGPSVHMGYTVPANSEYFYNEVTVPAGQDVVGSYFMVAGFSAGYAGIQVKENERWILFSVWDADNGQKTTLVSKGKGVVDNGFGGEGTGGQSYLVFNWVANNTYKFITRIRPDGSSNTLYSAWFFAPESNSWRYLATWKRPSTNTYQTGVHSFLENFLDTRGYTGRRVQYGNQWARTVKGYGVLLNAPRFPHAATSVNLQFNIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3E3</accession>
    <name>A0A9P6E3E3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HPP family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_865252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157990">
        <property type="protein sequence ID" value="KAF9521772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3E3"/>
    <dbReference type="OrthoDB" id="2016548at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="2">
        <location>
            <begin position="28"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="29118" checksum="76244A427B1204CD" modified="2023-09-13" version="1">MSPPNTLAHFPRWFSHWFGYRAGPPPKHPDYLIWFWSWIGAFCGISVIQAVFEQAKYFVKKGVPTIIASYGASAVLIYGAIEAPLAQPRALFGGHFLGALIGVIFTKLFHLLPTEEHFQRLRWLAGSLSCATALVVMQMTGTTHPPAGATALLAAVDDDVLAIGWYYLPVVLLSSALALGVALLVNNIQRRYPVFWFYPAPPPLAPAAKQMPNGMIESKRVPVPAIDADHEMASATTTTVEGGEIVSRAEESVLGNRRSSREPILPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3N4</accession>
    <name>A0A9P6E3N4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157971">
        <property type="protein sequence ID" value="KAF9521951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3N4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="27984" checksum="5CB6AB95C9920AD8" modified="2023-09-13" version="1">MPRASPDNTETDGPQRVELAKHTQAAKVKHGKIAKKDTEIVRRKMEIVKRDQDIATKEKEIVEKQKDIKTKEGALAKKDKQLAKKDTKLIKKGKEFKQKGKEIKKLNEEVEKLKKINEECKEEADALRGEEMKKDMVDLKSSAERYKEEARAMMKKAEPKASSLSSSRRAQSHTEEQEVAAVLTDADMASPMRGSFPVDSTGRQPHTVNLDDSDNDMYDSDRPVFKPAPTTPQRPNIHNTSSQPLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4I3</accession>
    <name>A0A9P6E4I3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4I3"/>
    <dbReference type="OrthoDB" id="3064136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="746"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="831"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="899"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="963"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1107" mass="117154" checksum="2D0AC1E191EDC772" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5G4</accession>
    <name>A0A9P6E5G4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5G4"/>
    <dbReference type="OrthoDB" id="2349272at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040111788" evidence="1">
        <location>
            <begin position="16"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="217" mass="23255" checksum="53C0782B63F433B5" modified="2023-09-13" version="1">MLFFQVLPFLVLVNGLVTRQKPNSLLDQIQQVCPGSSTCAGAVAPDECRTATQSAPFFATALNGTTPGVQAAIFSLVCFETLDLDFRTNHFPGRPGQGTSSMMMFDFVLEYARTFPELGPQIDALVGSGVTTDQQKNDIRALVLDDKYNFGSAPWFLKNKCDASVSTALASGTDAAYAAYITQCVGTTLTDDRIAYWTRAKAAFGPFGLATCSSNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5X8</accession>
    <name>A0A9P6E5X8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PCI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_60312</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5X8"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="189"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="391" mass="43608" checksum="69F9212B9CDC6409" modified="2023-09-13" version="1">MASTSSSSAPSLQDQEASLVKLGEKYRDENNAEGLSDVITRSRAFMSSTAKAKTAKLIRTLLDFFNAIPDSREVQMTTLTDNIAWAKSEKRIFLKHSLETRLVALQLESQQYTPALALIDTLLTELKRLDDKMILTEVHLLESRVYRGIGNMVKAKAALTSSRTAANSIYCPSSLQASLDLQSGILHAEEKEFKTAYSYFFEAFENMSAQGEDGALGALKYMLLCKVMLNLAEDVNSLLTSKLALKYANRRDVESMRAIARAHQNRNLADFEKILKDYEAELSSDPTIRSHISTLYDKLLEQNLLRIVEPYSVVEVSYVADTVGQERQAVESKLSQMILDKILYGVLDQGRGCLIVYDQPEVDNTYGAAIKTLEQVGKVVESLYAKSVRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6M4</accession>
    <name>A0A9P6E6M4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">B-block binding subunit of TFIIIC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_821291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="68020at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042791">
        <property type="term" value="P:5S class rRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16169">
        <property type="entry name" value="Tau138_eWH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046488">
        <property type="entry name" value="Sfc3/Tfc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035625">
        <property type="entry name" value="Tfc3-like_eWH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20222">
        <property type="entry name" value="DUF6581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="B-block binding subunit of TFIIIC" evidence="8">
        <location>
            <begin position="142"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor tau subunit sfc3/Tfc3 C-terminal" evidence="9">
        <location>
            <begin position="1398"/>
            <end position="1748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="513"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="647"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="899"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1346"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1641"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1237"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="690"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="712"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="731"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="904"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1346"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1374"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1655"/>
            <end position="1666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1944" mass="219356" checksum="5C9B13CB750064E4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6P2</accession>
    <name>A0A9P6E6P2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_898575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6P2"/>
    <dbReference type="OrthoDB" id="3066004at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="734" mass="82485" checksum="2B5BE6B5960530EE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E713</accession>
    <name>A0A9P6E713_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_839625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E713"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="66"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="68"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="296"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="477" mass="53668" checksum="1394687D5C2AE072" modified="2023-09-13" version="1">MSQSPTAYRGASAYYDSSQDTEDEWNVASPVFATTMHSPRSPLHSHERERRSSIGPMRTSGGATREKEKQKRSRVTPEQLVHLEQYFSVDRCPTSARRKDISENLGMPERQTQIWFQNRRAKAKQEDGKQSHQPATPSQPDILPIVPKTFEAEFQYLIEAEQPITIIPCADLSVGTWRRIASTINNHDLVVYTSKRNQCLTWFIHSAGYGFKMDLPFSTIVDTEYKIVSTHAGIASLTLSQPPVFYMQSKTTTGNHAWKRVSDWTEERQATKILRHTLVASAEHLSQFLRTLHDSRSVESPRNPVSRRHSEAAVPRTMRIPPPPPMASLGPPSLEYTLHCPVDRVETAIQHFYDPTGHTMLPGAGFQPSSPSTQPAAVLSSPYNPMGTHFHHVKSPAPDLFSYFSPVDSSQLTLNYNNHLQAYNSGLDQYTHSQSCDGLQATPIPAYPTEYTSSQLLNSPFQPKQSSASMENRRYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7B1</accession>
    <name>A0A9P6E7B1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_655111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7B1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23881" checksum="7638388F88ADE5CC" modified="2023-09-13" version="1">MDVKPKSSIHDVVDPDSAPRAPRPDDKLEEMYSKLQKSFAKLEKEKAHLEMKLKESERQSQVTRVMLQTRCRHYYNAALKAQRERDELQEEMYALKHLEQRVQVLQVLVDDNVSPFLTSLDTFKSKVTDTTNFLYEHVVFKNYEAFEDEKQEALGGILSWLSIPLVQLLVTCAENAAASNSVGGSHVLIRVSSWALLYRHLGRCLSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7R1</accession>
    <name>A0A9P6E7R1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Prenylcysteine lyase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_948737</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7R1"/>
    <dbReference type="OrthoDB" id="437369at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001735">
        <property type="term" value="F:prenylcysteine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030327">
        <property type="term" value="P:prenylated protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030328">
        <property type="term" value="P:prenylcysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036292">
        <property type="entry name" value="Prenylcysteine_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040493389" evidence="8">
        <location>
            <begin position="18"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Prenylcysteine lyase" evidence="9">
        <location>
            <begin position="156"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="552" mass="61307" checksum="C1292F3D0D45D362" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7Y2</accession>
    <name>A0A9P6E7Y2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_861739</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7Y2"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="61" mass="6848" checksum="D904E7BDE273A22A" modified="2023-09-13" version="1">MLIFEGDADFISNYVGFVSMVDALQTQFSTAYHSQVWTPYKVNGQVTGQYKAAGTFAYLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8T4</accession>
    <name>A0A9P6E8T4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_613127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8T4"/>
    <dbReference type="OrthoDB" id="3215907at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="588" mass="63101" checksum="895BBAED3377790B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E934</accession>
    <name>A0A9P6E934_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E934"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="277" mass="29861" checksum="86322C8264868821" modified="2023-09-13" version="1" fragment="single">MHPTEEFEDLVLSFGDDVTHTLQPHPSSSPTGPPSQHKTQILCEPSLSTSMDAVDAQAFPSLNFGDGVTDMSAAASSMSGNIQMQHDDPMDNSFSTNILQTQSRGHIALETHPLRPEHSTHGSESLLSPQPKLDFGVLSTQESVLDVGSNESSQLSNIDFGTVSTKGFVVKPAATSPPTFMRTQPVQMSSVELDFGFSSQERPGLDFGMSLTQPEKLIEGSSRRQPEPEFGLNLAHAPDLDFGMIMTQIPELSPVCPGGQPELGFAMNLTPPHELDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9A8</accession>
    <name>A0A9P6E9A8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_819568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9A8"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF161">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="36743" checksum="DE20129D6F6E5D38" modified="2023-09-13" version="1">MLAKAVDGSNKKDPNFPQGLYIHPSQNSISLVSSFDTLLLQTFGPEAQEQAIREYGIAGRVWEAAYAMIAFISSPLGLEFDPPFLAAKSTNAERHIILELGSGSGLIASVVSKVLNIQHDRMIATDLPEVCQLLESNLQTLLPDKQRGNQATKFSIVRVFPLPWGDDLAMGKLATTFFDSRSLDYNGSLTHIICSDLVYFPELLAPLLRSLIKLTSPPFNNNNTVVVYISYKIRSLVKETPFWSAFGLWFHFQPVLFKRRSEVEGDDWERFGQDSDDTTYLFVAARRHGSFKWKIPKADDELLGGVGAQNNNSRKGDDTFENLLLMSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9D8</accession>
    <name>A0A9P6E9D8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_860781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9D8"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22927">
        <property type="entry name" value="HFD_SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037782">
        <property type="entry name" value="Spt7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="58"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="253"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="393"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="700"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="783"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="703"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="811"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="880" mass="95245" checksum="D624652B83EB0B47" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9F4</accession>
    <name>A0A9P6E9F4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9F4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040323380" evidence="2">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="52" mass="5125" checksum="0DC2EFF9ECCE82D4" modified="2023-09-13" version="1">MARMSILTAILTAIILLASTSVVTSAPLLDGLLGGLLGGGGGGCVLFYVLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9P8</accession>
    <name>A0A9P6E9P8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="8">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_860052</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="8"/>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9P8"/>
    <dbReference type="OrthoDB" id="10254258at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009159">
        <property type="term" value="P:deoxyribonucleoside monophosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000011">
        <property type="entry name" value="HD domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0170">Cobalt</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="13">
        <location>
            <begin position="46"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9525126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="23506" checksum="CF7AD34BF39840D2" modified="2023-09-13" version="1">MESTRIFPPLYKSTENAAKDRLAFIHVLERLKTQKRTGWVNHKIPNAESISDHMYRMAVMAMLCEDNALDMSKCVMMAVVHDLAEAQVGDIAPREGIPKAEKHKLEAEAMHNFVHDMLHNSPAAQKIFELWQEYEDGTSAEARFVKDLDRFEMASQALEYERRHATDLQPFFESSIPKLQHQQIQGWGQDLLLERDQNLLEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9V6</accession>
    <name>A0A9P6E9V6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9V6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="52663" checksum="29EF253CD643391A" modified="2023-09-13" version="1">MSEPLPPELIALIVGFLPRWNPFFLNHPSPSLLSCTKVSQSFADAARRRIFSTLTILPSKFTSGRFEMLLTLLKANPKLLASVDTIDIKVESKPYLNRIKDNDTTLGCVLRYLKRGAINFAHLKMNCPKAWDFTWEFGPLAQQAISELIPGLQTISFASFMVPVSFLNFNESSPPKALHLSCVKLYLSLNKVDPLPKALLAQSRISIDETSMEQLDQWYQKQLEVPAYTDLVIHPCLDDDFYISKQTFGQALQGSANTLRRLELHLSQPQDWYSLSDLGCFRSLTSLLLVFQYNNDTDLKLKSSWSVTQLFAFIKEALEVTSRILGSTSSMSRITDIALTIAFDGRIPESSASTDDDPENGPLNGCFYELDVLDPTVLLAKHPVLKSIKVKISLPQLILVKGDWAQAESRFRAVVRTHLEVALINSFEGTHWTREALETLYDIQITKQYCDIFQASESNIYWRSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA52</accession>
    <name>A0A9P6EA52_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_772313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA52"/>
    <dbReference type="OrthoDB" id="3366231at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9451" checksum="1EF46C72C0C26C27" modified="2023-09-13" version="1">MDRAVSRYRHFNNEQRDVFDEVWDAVEQGRPLCMFVEGKAGTTTIINALCDALRASGRIVLPTATSAFAGQLYPGGRTTHSMFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA73</accession>
    <name>A0A9P6EA73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_563363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA73"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="78"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45817" checksum="6997B95F16F99145" modified="2023-09-13" version="1">MHTTAPVYVPLPTSSPSIALSATHRKDMHTGVENRPLQLSFQDLTQETNETNHSQVQSIQAPVLQDADNTPSSGIPNIIVFGETGTGKSSLINLLMGTPVASTSSGAVGETFLSEGYDVVIHNRTYRLWDTAGMNEGNQGTVPTDKALNNLRDLVINLQGGADLLLYCIRGGRYGDILRVNYDMFHGIICQGKVAIVLVITGLEQELSMESWWLANKQEFEEYELHFSDHACVTTSRGKKMKDGFYSFQEEYDISKKVIEGLILKNCPDKGWSLTSEAWIAQMGWRMVEYMNEFNRRSGNERHTLQEDYAGREEVHHHSHPEAFLAEPPADRVEGGQMARRSKILDPINHDAVKNFLRKLIRRIHQIFFNDDLPPNNLPHELNRNPSDGPPVPNVHVQEQRTTLASAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAG5</accession>
    <name>A0A9P6EAG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_944065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAG5"/>
    <dbReference type="OrthoDB" id="3223377at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="152"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="29951" checksum="D1CA6FC892BEC142" modified="2023-09-13" version="1">MLNWSLFGVLSMQMYIYYVTFGTDPLHNKLLAYGVYLLEVIQTILLTQSCFHAFAQGFGDFNQMDEIGTLWFSVPTLSGVVACVAQLFYAYRIHILARSKFIVCAIIALSVLQLGGGIATAVMSKRAIFHSHFLGPGSYKTTGVSQIWNGSSMLCDVIIAICMIVCLSHRMNGLPSTRKLVKKIILLTVETGSITAVVALLNFILVLLPTRPTYFLTPVAILGKLYSNSMMAVFNSRIHFSMANEQVSSADPPELAHASLLRPRLQTSSEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB03</accession>
    <name>A0A9P6EB03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Anaphase-promoting complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_817653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048971">
        <property type="entry name" value="Apc1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041221">
        <property type="entry name" value="APC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21282">
        <property type="entry name" value="APC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18122">
        <property type="entry name" value="APC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="7">
        <location>
            <begin position="62"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 beta-sandwich" evidence="9">
        <location>
            <begin position="1579"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 C-terminal" evidence="8">
        <location>
            <begin position="1709"/>
            <end position="1877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="319"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1949" mass="216560" checksum="975CA92F0825DFAE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC60</accession>
    <name>A0A9P6EC60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Proline iminopeptidase</fullName>
            <shortName evidence="8">PIP</shortName>
            <ecNumber evidence="8 10">3.4.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_858036</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.5" evidence="8 10"/>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC60"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005944">
        <property type="entry name" value="Pro_iminopeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01249">
        <property type="entry name" value="pro_imino_pep_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722">
        <property type="entry name" value="PROLINE IMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722:SF1">
        <property type="entry name" value="PROLINE IMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006431">
        <property type="entry name" value="Pept_S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8 10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="11">
        <location>
            <begin position="38"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006431-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9526401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="35817" checksum="BBCBA8F2C610974C" modified="2023-09-13" version="1">MSEEILYAFTEPFDSGKLKVSEIHELYYEVSGNKDGAPVVFLHGGPGGGTSPKDRGFFDPKKYKIILLDQRGSGKSTPNACLEDNTTWDLVKDVERLREHLKIEKWHVFGGSWGSTLSLAYAQSHPDRVKSLVLRGIFTLRKSELKFFYQDGAGHLFPEAWDDFIAPIPETERKDIILAYHAQLNSVDDETRITAAKAWSKWEMATSRLYQDPVQIASADEDQFANAFARIENHYFVNAGFMREGQLLEVQEIDKIRHIPTVIIQGRYDVVCPATTAWALKKAFPEATLHIVADAGHSSREPGISKLLVQTTDKFADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECK8</accession>
    <name>A0A9P6ECK8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GTP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_856880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECK8"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000229">
        <property type="entry name" value="Probable Ras-related protein Rab-6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="211" mass="23509" checksum="71B73E94085283E7" modified="2023-09-13" version="1">MDASTPVSADFSSSPPKRTKIVLLGDQSVGKTSLITRFMYDTFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIVVFDITNRQSFLSTSKWIDDVRSERGNDVIIVLVGNKADLSDKRQVTLEEATAKATQLNIMFMETSAKAGHNVKSLFKKIALSLPGMEKDTQTEANTKIDVTTQSTDVPEASQCQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECL3</accession>
    <name>A0A9P6ECL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CPB83DRAFT_870417</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECL3"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="21">
        <location>
            <begin position="82"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAF9526438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="606" mass="66334" checksum="C2D7B6E92233520B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECY3</accession>
    <name>A0A9P6ECY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_769125</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECY3"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="508"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="318"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9527141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="59150" checksum="5BCF504DACA292CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED17</accession>
    <name>A0A9P6ED17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_857591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED17"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="57817" checksum="4431320E9F5C513E" modified="2023-09-13" version="1">MMKNLPQELLSEIFIACLPPPNEIDQHIRDPSSPPLLLCQVCSTWRTVAIKTHQLWTYLHIWVIHLIRDNSLTSLDTSYAAESQLVDLWGSRQGALPSSIFFQGVKADRRVEDENKHLTFFGDILSHLAVVSCQLFAALEVSFRDIELVVERMIEGEFPNLEFLAMSGPYLHLVEDSGAAPVYRKTVTSIKIAPNLKRIYLNMHPLYRIIGDADVMSKFHWERVTHLAFAFHSDLDINLWYFLLRECISLTHLTASLGLEVDETWLHSRHKQPVLHRNSLQEIILQLSFADTAIIFIGFVYHSVTKFRISFSDLDATEFTDLDSTHALLSSTPNVQELHTQYMFPLGEGDRLHKFLAGTQRSEINSSTNDYHQQETFYPPLSSIIPSLRTLVVDCVGESVNDAAIPGDFYVILRSRWLSYGWPSSAPDSGRSILFVVDSDFSKLDPNEPLFIKASQHNDVRFEHPFQPEARIAPGRQWDWKVMNANNLKYGWDRCSAWLDSERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED67</accession>
    <name>A0A9P6ED67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thaumatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_768885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED67"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040309201" evidence="2">
        <location>
            <begin position="18"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="26"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="96"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="149"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="154"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="255" mass="26691" checksum="C4835AB4D960E083" modified="2023-09-13" version="1">MKSQLAYSFALAAGVSARTFTVTNKCSYTVWPALFTDLNVAKNVPSQPTGWEAAPGTSVSFQVPDDWKAGRIWGRRECDFTDNTKPGYLQCASGGCNGGLLCDTATGTGVPPATVAEWTLAGDGGADWYDVSLVDGFNIPMAVTNNVGCPVPDCKADLDATCPTELKKIGPSGAVVGCNSSCNANLDGNQANSPNCCSGSFNTPATCPSSRVAFYSFFKSACPNSYAYAYDESSGTALWTCPTAKKADFTLTFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDQ2</accession>
    <name>A0A9P6EDQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Delta-12 fatty acid desaturase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDQ2"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="440" mass="48736" checksum="F54108227BD28442" modified="2023-09-13" version="1">MGRKNDDQKVTVVEQGVYPVPDIPIKDMLAAIPSHCFQRSALRSSVYLVWDTAVVYGLFKATKYIDALITPAALSLPNPYLYPAAKVGLWALYGFWAGLFSTGLWVIGHECGHQSFSESKIINNTVGWFVHSALGVPYHSWRITHAKHHASTGHMTQDQVFVPHTRSGVGLPPFDPSREDKLGARVTEEVKKELWEALGDSPIGAVLGAATYLVGGWPAYIIRNASGQKRYPKGTSHFNTASPMFAPHHYGQVIISTAGVALWLAGIALSIKQWGFLTVFRTYLVPYLWVNHWLVLITFLQHTDPLLPHYRAPEFTFTRGALATLDRNLLGDLGSAMAWIGAHATNGISETHILHHVSSKIPHYHAWEASAALRKMLSTHGIPMQGAPAGWAEIYRVYRECKFVEDEGDVVFFKNAYGLAQMRPQLPESSASDSGIEIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEJ8</accession>
    <name>A0A9P6EEJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_384088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEJ8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="165" mass="18298" checksum="32A9A3CAA5A32712" modified="2023-09-13" version="1">MSPQALIRHLTAEHPNFGWWPGPQHRPPGGDGRKKATSAFETRMTGTKAKYSTPIPTTTSMPTANAQNQTNTTRKHVEAQEPKLNAGLIMAPILGVLLPLAAFIILFVVCHRRKTRNQTPPSVAVQPQVQRIGNKLLRERELAAGWWKARMPRSVRESTGPLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEM4</accession>
    <name>A0A9P6EEM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEM4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="248" mass="26758" checksum="5836D5467697FE0D" modified="2023-09-13" version="1">MKHSAGNPKSLPSPIRREDSKAIDDFHYERASLLDRVADIRVATVAGNAEATSSDVGIATIPGPPFFDRSRTSYSSLPETIGKTTLIRSASTSAPNSEKQMPTSSTASTVNHQSLPYPTAANSMAGTSPPYSQPQARGRPDESGISQSVIVGLVVGLTALSMSIVVFFFIWRRRQRSVKRLQAHPFSNETTVAPSPFSISKSDILRQYNLNSAEQGQNRGQVAVFGSATLGKLSSSKTKYPSPPVYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEU5</accession>
    <name>A0A9P6EEU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">60S ribosomal protein L14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_384831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEU5"/>
    <dbReference type="OrthoDB" id="1875589at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000030">
        <property type="entry name" value="60S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein eL14" evidence="8">
        <location>
            <begin position="51"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="15446" checksum="1AF17F7B2D61932A" modified="2023-09-13" version="1">MSAKDSNFKRFVELGRVVLLKSGPSAGKIAVIAEIIDHNRAIVDGPTTGVPRQSFPYKHLTLTPLKLTGLPRAAGTGVVKKLVEKEQLTEKWEKSSWAQKRAAVEKRRSLNDFARFGVLLAKKSRRDQVRKAVKKAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFK6</accession>
    <name>A0A9P6EFK6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_855023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFK6"/>
    <dbReference type="OrthoDB" id="3202243at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="502"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="648" mass="73736" checksum="81C6FFBD427AA709" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFR3</accession>
    <name>A0A9P6EFR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_353205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFR3"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053025">
        <property type="entry name" value="Mito_ATP_Synthase-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="31"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="211" mass="24120" checksum="6F48090B36CCAC4C" modified="2023-09-13" version="1">MLSFSLKCSRSSPKWATPRKSCFSTSSQRLTHYDVLGVPQTASKSQIKSHFYKLSKTHHPDVSNNPESAKVFRKASEAYAILGNDRERRAYDRTILHQASPPASTQSFYQPSPSKRGPRASHAWEHRTRKKPPSPERPYPNSSSSYANRHYDAPKPYRHALHHDVLVGQRRRTEEEDQRVDRLKREVPFLRAVQVTSLLLLAVATFSGFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG56</accession>
    <name>A0A9P6EG56_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_894556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG56"/>
    <dbReference type="OrthoDB" id="2940323at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="38545" checksum="A6671725CC9FC895" modified="2023-09-13" version="1">MSLQLPPFYRTPKFFIVTLGVACSLWLLLVSYQSYVRGSFVSLKNDVETNIVQRRQLVVRTTPTNRAGIGSVLAQLRSSAAIATILDADFATFGLQSEHPYRVASLLHLDLLEHPLTVESKVCSISALPTYSRVHNLVESWCNNPNADSEHAVELRESLKDCDLILDDRPWDVRQDMAKCTWKWVKQVFSKLGVNKQAGGVGIHIRWGDMASGGDSKDPKTPERSIPIEVAAKLLRKMRECGVDDELSVYMEAHNLTLLDGLGEPYRLVDTGNDINDLVDLASNRIMVLDIGSYTAIAHQISDGGVTVVPDVDEFGISWHNIGPNTVLRWNELLSISCSELSTLLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG80</accession>
    <name>A0A9P6EG80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG80"/>
    <dbReference type="OrthoDB" id="2317741at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040172538" evidence="1">
        <location>
            <begin position="19"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="130" mass="13748" checksum="4667D6C0C4683BF3" modified="2023-09-13" version="1">MKFSIFAAITTIVAAVSASPLAGLEARDVFVPPITSPNANTTWISGQTTMITWDTSNHPVNITNKVGLIFLRKGPSMTPLILAEKFDILLGSIPIQVPNVVEANDYAIVLFGDSGNISPPFSITGSGISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGX2</accession>
    <name>A0A9P6EGX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGX2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="7926" checksum="FB9542DBCA4CD166" modified="2023-09-13" version="1">MGCFLSTIWLVVSLNRRMGRFEEALPSYLGSLITKPLFPGCRGSLKWEKCVFTFERIGVENLISSLLSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHG1</accession>
    <name>A0A9P6EHG1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc finger Mcm10/DnaG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_812965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MCM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHG1"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="3">
        <location>
            <begin position="399"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="557"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="697" mass="77160" checksum="25C386B162953631" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI69</accession>
    <name>A0A9P6EI69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI69"/>
    <dbReference type="OrthoDB" id="3039061at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="274" mass="30609" checksum="D3E78C4E24CD444E" modified="2023-09-13" version="1">MAVIAGLLHHLPQLQTVWAKTINWVIGANLSGPTIRKSKKNLFDVRIPITLNHVRHLAITAPGTGTDILLCLDAPALYQVHLDGTRGHLFDNPYARANLIWSRAETGRVQSSLKRLASRSPNLRHLALTATYLSEECWTWLLLGSTVEPPPFHCLESLALHELDSQSGKVACGFTEAGLLRYSMRSDISLRKLSFRRCTFSIDGAVLVQVFINFIQQRPSNSFTLEIDDSFKGITDDHLDRLRLVGVVVRNIGRDVPGWWSHGHQIDALDSTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIE5</accession>
    <name>A0A9P6EIE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_852916</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIE5"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13170">
        <property type="entry name" value="RanBD_NUP50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053074">
        <property type="entry name" value="NPC_Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015007">
        <property type="entry name" value="NUP2/50/61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697:SF1">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08911">
        <property type="entry name" value="NUP50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RanBD1" evidence="9">
        <location>
            <begin position="475"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="96"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="255"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="612" mass="63026" checksum="F2F79622AF4BB2EF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ53</accession>
    <name>A0A9P6EJ53_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_764224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ53"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF28">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="56285" checksum="B8AE3BD21BF87CD8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ68</accession>
    <name>A0A9P6EJ68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ68"/>
    <dbReference type="OrthoDB" id="3351042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="470" mass="50812" checksum="AFED83F8A3FB765D" modified="2023-09-13" version="1">MPEVSALGPIDPASLPETTEQEKNAPWIVRKLVGSMTGRIVMSSYETLRAAGTNIICLSPWGDSSPLFLPCIRFRDLAVHTVIAATGGMAAIAAPVMGPVADVVVTTFGDTILVELGIHAGFDLTTKVADDLLIDKPINKLVPIYSKRLETTGVKILLITLKYKHTMTDASLGFYRSSIHKDTSLFAAVKDYLAVEKGWFSPYLFASSRRPIIPRNMKPDVIFCHGPFLAGDYRVGETLLAESASVITLCASATAEVTESVDKNSSSTAQPITKGLSLPSLSNMFSRSRTPSPEPALTLLPTPPLPRRMVILVVGLKPHRKIWTLSARPGESVINYILLNGCPSIVVPVKLGAPLVAWDALTLEDIWKVELPKDDGSKTVSGKFEGIVNVIFEYLDLCVDWERFQIPNEGGGASVKDEEGSEGEPRDTTKDALKDAVTLLVAGAVRSKGSKEASQELDSERSGIAMWRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJN2</accession>
    <name>A0A9P6EJN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJN2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="192" mass="22226" checksum="EC9C6ED0FB247C55" modified="2023-09-13" version="1">MEGRRRGVRRTESQNGAPRATDLGIAIRYGDSPPSLEIQNSTMLTDAHTGASASNHTELPPAYVERTPCLPTYDLVMSMRRRQHSVRRSNPNHRQSSLPAWLDSNHRQRRRNEETVSRRREMGRVEAMIRQERQRPMREREESHERRVQQQQARLDMGSPLGAFRENEAQLGLDLNDQEMDVLLRAFGVPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJR3</accession>
    <name>A0A9P6EJR3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PIN domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_922616</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJR3"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09901">
        <property type="entry name" value="H3TH_FEN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="549" mass="61540" checksum="C2E35E39D13241AF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK82</accession>
    <name>A0A9P6EK82_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_834451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK82"/>
    <dbReference type="OrthoDB" id="2562493at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="155"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="259" mass="28598" checksum="9F45740A207CCA0B" modified="2023-09-13" version="1">MGQVENVLGTLLIGIFFNTYLYGVVSFQYFSYFSSKIRDAFAMKAIVALLFANDTFQSALVRNFVNPVFMNYITWPYAYVPIGTAITAVATHLPLASRIYFMSKKKWIFVLLLLGSLGSLGTGFALGVFVWTLKDIHRADRLLKTLVTVWLGIQAALDVMLAVLSTMFLHNQGKGADQKTSSVINRLILGSVQAGVVPVLFGAAALATFYLFIMFVIPLGRTYTIAFVNGLNVREELKERLLGSQESADPVVVQDSLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKF9</accession>
    <name>A0A9P6EKF9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_834216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKF9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="17476" checksum="07BF0E27CA4ED6C5" modified="2023-09-13" version="1">MAAAGSDDMTMSVLKAEWNEVQRKLRQADLTAEILLKAHRTIEAKDRAIQLLTSQIDTAKKNIKSVKLLALTHERLLDHLVCFTCGELLRDPYICIMTWGDACGRARAQLRGETIDPAEPPFYLKCPTCRVHEDNPIQNFFVKSLVAALAREEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKI7</accession>
    <name>A0A9P6EKI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_762756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKI7"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03484">
        <property type="entry name" value="MutL_Trans_hPMS_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000014">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="3">
        <location>
            <begin position="222"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="370" mass="40380" checksum="6C5EE364855DA080" modified="2023-09-13" version="1">MSTIRAIDQVTINNITAGQVVIDLQTAVKELLENSIDAGATNIEVRFKQYGLSGLEVLDNGSGIAPENHKGIALKHHTSKLSSFSDLDSVSTFGFRGEALSSLCVLCGGATVTTATASMEPKATCLVVDITGKVIKQSSVARPRGTTVSLTKLFSSLAVRRKEFERNIKREFGKALALLTAYALGPCASGTGIRLTVSNQPDKGQKTTPIKTLGEPSFRSSLTALWGNKAEENIVDMDFSFEVERERIKRSQSQDLGSIPIRVRGLMSKFAIGCGRTGKDRQFLYVNGRPCDLPKVAQAINDTYRTFNANQLPFILADFILPTDTYDVNVSPDKRSIFLHSEANLIVELKVCVHRIFAALTLIYVFSRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKS9</accession>
    <name>A0A9P6EKS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_868391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKS9"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000095">
        <property type="entry name" value="Triglyceride lipase-cholesterol esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="11">
        <location>
            <begin position="29"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9530668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="403" mass="45286" checksum="0AA93936CF9AA470" modified="2023-09-13" version="1">MGLFSQKLSPEEAEELRRAQQVNRARDFTDICAVFGYECEEHSVTTDDGYILSLKRILPQERHERSVQRPVVYLQHGLCTNCELFMAVSNPRRCLPLVLVENGYDVWLGNNRGNKYSRNHTTLPVASDAFWDFSIDNLAISDVPSSVSYVLECTKQPKLSYIGFSQGSAQAFAALSVNSKLNQQVNIFIALAPIMRPKGYSAKLVDMMMKRNPKSIQLFFGIRALFPIVSSLQCILPTFFLNLAVDYAVYYLLAFANYNITKVQKLAAYPHLYCASSVKAVVHWAQVMRAGQFIPFSDDTKHSTSPRTKQIYGNGNGNYHIRPDSIEGTLQRYPTENICTPIVLIHGDSDSLFDLEPMLEHLPLSGVHCIGLKGYEHLDVLWGKNVHVDVIPKVLEGLQSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELX7</accession>
    <name>A0A9P6ELX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_761944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELX7"/>
    <dbReference type="OrthoDB" id="3133286at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="34705" checksum="61DFC792F2211783" modified="2023-09-13" version="1">MDASPQPSTSIGPAAEKTAVIPVIGPSSRFSRDRRQRTPQDKPPIQGQSQSQGQTSAPTTGPTPTQILFDITRQVVQILKEAGIGSALFGSLGTSLYGKQRSPNDIDLLTFPPPDQNSDPERIKQLIVTANPDKFYLRDSVNPSATYKILFYKLTRRQNPTRFFRRNSCKVDILIPGIMHLPSLHPNPERIIWIDGLPVLPFAVLLSQKLQAWDDHRNMSEETEPQKYAKRFVDKNDLGRMFKMEEHVRPLREASARPWNDRILFSEEFETLCWSRARDFCSIFPEFKARFLSIGLGEDTYDIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM27</accession>
    <name>A0A9P6EM27_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_808926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
            <location evidence="1 6">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM27"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040528774" description="Hydrophobin" evidence="6">
        <location>
            <begin position="20"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9531297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="112" mass="11302" checksum="EEF7CBD7EE89D1D7" modified="2023-09-13" version="1">MCSKLAIFVATTMAIFVAANPAGTDGINNSCNSGPVQCCNSVSEADSKQADFFKSLLNVAIPIGTKIGSTCSPISAVGVGSGSSCQSQPVCCENNHFNGLVAIGCSPINLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMT8</accession>
    <name>A0A9P6EMT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_50481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMT8"/>
    <dbReference type="OrthoDB" id="2751409at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="45"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="824"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="938"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="682"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="824"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="878"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="939"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1031" mass="113742" checksum="DCAD449C8F765D1B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW9</accession>
    <name>A0A9P6EMW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-dependent phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW9"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="298"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="668" mass="75142" checksum="A43A7AC3457C10A0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN54</accession>
    <name>A0A9P6EN54_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_663643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN54"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF26">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="244"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="813"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="814"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1021" mass="112278" checksum="EC56F5D07ABA68FF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENS9</accession>
    <name>A0A9P6ENS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre protein translocase subunit Sec66-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENS9"/>
    <dbReference type="OrthoDB" id="73168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018624">
        <property type="entry name" value="Sec66"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229:SF1">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09802">
        <property type="entry name" value="Sec66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="235" mass="25815" checksum="795BC6D868AC9F37" modified="2023-09-13" version="1">MTSVLVPVAYLVIVFGGLFVFSFYYRKATSQKKYEPYFPSHPERNAYVTLLQKNNPPAHDALLKSALIRRAMADVQRVVRIREDKAALQNLLQKGSVGDDLWNSLLAAEKEMEAEIMEVVGEANSFVEGWGQVIFQTANEMIVNEKMRAIFERTNEAKTEIEAKYELTRSRPTPAVIEPSAAGSAPPTTPAKTANGLLSPTSPTYTDSVVSSDGEGSVTSASGTRGGKKKNKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENW9</accession>
    <name>A0A9P6ENW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_807107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENW9"/>
    <dbReference type="OrthoDB" id="2103474at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="30083" checksum="BEEBB9DA290835FF" modified="2023-09-13" version="1">MSQFVTKASKTYGKRLFAQHLDQYTPQDPLYEFYTDERGVERRRKRDLPPGLSKRDAKILKSVKKRAHYLDKGFSICGMRFGWTFFISLIPIVGDVTDAALNYRLVVHKARKADIPPWLLKRMLFNNAVSAGVSLVPIVGDVVLAMYKANSRNAFLLEEFLRIRGEEFLKMGGVTEEEGKTGWLSSLVNKAVKGGVSAKDAEQVKPGAGMTKEELKAAGKKDMTTGSGKKRTYSGSSFGFFGSSKKNKSKTPPLTETNVPDKGRFVENVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP37</accession>
    <name>A0A9P6EP37_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_890452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP37"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="295" mass="32413" checksum="652DD58277201687" modified="2023-09-13" version="1">MESSTNSQSEQQTSIWFITGATSGFGQRFALSALSRGDRVVATGRSLEKLEKLVASLKPEYLERVRTEQLDVTSGEEEVKRVVDKAVKHWGGVGYPALAEEGGTKLLRRQFETNLFGVADVSYAALPHLRQSTNGRLVVVGSRSAWAAERKGLGLYAASKAAVNTLTENLMSELEPFNIKVLLVLPGSFRTEGIYDQGFFTSNKIPAYDEMRAACIKRFGSIAGTEQGDPDKAAEAVVDIVQGRGVAKDRHWPSYLVLGEDAEADIRSKCSKRLANLDEWADVTRNVKIDKRLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPF8</accession>
    <name>A0A9P6EPF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligonucleotide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_846912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPF8"/>
    <dbReference type="OrthoDB" id="627262at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="670" mass="71814" checksum="767B45F3B001F555" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPH1</accession>
    <name>A0A9P6EPH1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPH1"/>
    <dbReference type="OrthoDB" id="3229088at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56503" checksum="68F66879E258CB96" modified="2023-09-13" version="1">MERSLSYTRLQMRQGTVKAPPPRKDKKTLAEKAVAELQIHSRHTCDDHCQSSSERRDQLPKAIASYEAYQEKDKRIAEVERMLANLKCERNELIPIAKLPPEILTAIFTSIACNSAYVFKPVASENIVLRYNFTYVCSTWRNIAISSPALWNILPVNATPINWIPLLIERSCDSDLTIRFADDDEDLESRVAYIFWVHGARIREIKLTRCSNQLIARLPTSTPRLTRLSLSADGDEDPVIKLPRSNTALRTLKLSAVNIDWNSYPISAGLTRLKIQDPPTHITWSLLLRMLRGMPSLRTLELLGAMSPFDPTSLPSNQSIILEDLVELSFSSSLRNTSNFLSLLAAPLLKSARLVFELEGAEFVDRPSISHISDFFSVLRTRPSTNNKFQTAVVESKPKALTYQLWRMKIDDPSRYLVAPDISLRFSSNVSFKTYLDEIIQSSVVSVGFQDVSILSLNLDADASAMASTFAKLPLVEKVVVPGNFDSFLKTHHDYCPEATPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPH8</accession>
    <name>A0A9P6EPH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_807004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPH8"/>
    <dbReference type="OrthoDB" id="2564485at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48198" checksum="07B5BA78B627B752" modified="2023-09-13" version="1">MPFHIEYPVTRTIRWRWLGPISFLGAFIAIVLLTVLNVALVGYETVNVFSDDFMTTQPQWYHKFMPYRKPKPGSLCDAHLFNVGDRFTTNYTIFEWVVQSVNAPNAAKSGVSYGGSPLNDCDVTKIYMNGDLTRYTVQFSVVMACRDREKFGVTATTSFTISILPGILPEIFGTSRVVDGGDAIDPRPWAISELIRFAATDLGNRAKTALVVSNGATPVVFSVTGSFDDNSFCPASKSSSNCGTQRPIISFPEAVSITLNGTTSGDDNTPGIDSLTEAPVLNIMQTVYAAARIDLGIDSLNNFILHNQSLPLILNKTFPATPFTPASQQQALTSELYANWENPAIAFQDTNLTSYLPLTSTGPAEVQLVYLCRFQRRKSVGSLIISVLVAVLSMFSSGWGAYMLLLTTMAKRTPDSNSCEGHLAEPYRHLQQTPEKFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPL3</accession>
    <name>A0A9P6EPL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase C15, pyroglutamyl peptidase I-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_846430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPL3"/>
    <dbReference type="OrthoDB" id="407146at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="42618" checksum="7112A00113846265" modified="2023-09-13" version="1">MPAVHGPNDPPQTANAVPPNSFRVLVTGFGPFMHYEVNPSWLAVQPLQNVVLHTDIDPEKVKASMPSVASTSPTAKLNGAMVNKTAVKTPPQPPFEIPTTPRPIHITTFKVPVLYESVLEKVPPVHLRPPVLPEDAPEDCATPPPNGYDFVFHIGVAGRGPLRMERIGHKLGYHMKDASGKYAPVVKVLPKDFSRREGGNGNDALTVESSDGLSAGGSTFVSVNGMVISPAESAERERLGMDMVEGSISADTISRPSRGFGVGYENCHEEYTTDIDVTRLVSDLKKDGVEQIYSSMDAGHYLCDFIYYCSLAEVKRTAKPYEEKRRTPQVLFLHCPPVNQPLSTEQVTDAIKKIIVWVCGEIMIQQARDDAAAAAGVSPAGAPPGASGSQKVIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPT4</accession>
    <name>A0A9P6EPT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_525402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPT4"/>
    <dbReference type="OrthoDB" id="2996433at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248:SF2">
        <property type="entry name" value="FUNK1 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38248">
        <property type="entry name" value="FUNK1 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="414" mass="47480" checksum="EE542F55061DDD66" modified="2023-09-13" version="1">MSSGPLTEMKAKIFFLRNDPPQNTQPLFFKTIGPLSVRRSDYISHRATRVWLVEPIASRQNVESTGETCLLVLKDTWSDIDAQTEKEIQDALFNDIKCFSKRLANAVDSGDWSLLEPDERDAFGSLMDKEKEPAKNLLRDEGYRKHFVTILQDWKGRTLKPPGSQAESIRAVPLFYQSRPRQYPGKTQHRVLCKEICEPLDDVKTFGEVIVGMEGAVSAMLILFLAGWVHRDISASNVMMYQGQGVLGDLEVAKRFRVRHQHSDEDFLKGTPYFMATEIYKGFTQARYPRPTIRTWDFTLNPKPDKRIPFQHNFLHDLESIWWILLWTMLQRVPFAPSHQYAAGLFVNTRNIPQAREEAFVAGGALISSLFTSLHPCFLIRDFDCTVDLLRCEMGDTCDFFDISRGSSNVWSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ46</accession>
    <name>A0A9P6EQ46_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ46"/>
    <dbReference type="OrthoDB" id="74813at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="600" mass="64801" checksum="811E9D5841F81FAC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQC8</accession>
    <name>A0A9P6EQC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQC8"/>
    <dbReference type="OrthoDB" id="3222453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="477" mass="53262" checksum="90204D27705EAAE8" modified="2023-09-13" version="1">MESQPVEDVPVDDEVEHEEHQSRHSSILGPYRKQVPFTQFPIYHPTTISAYQPAVFSRSLMSTGYGFAPWQPGANERPETHFHQGMSIGDVGFIGSDGALHYRFNIFHPSDHPIQPPTLPRTFRPIEPPLAEWDIRTSEDEITEGTVLTSKGVNATTISENPLEMEFKSKAREGAVLVLPEGAVREDLLDTHKLYKYVKEYASDWYQFLNDYNDFPTLTPVVNGTLFVVTGTDKTKVYSSALFPFEEDERCRATTFKYMAKSVKDRHWSPAPSVTCSSEGLTNADGEYPSAIFIRGLTVALSKPLWTHGIAPIPLTSLPLYYIPSIPLSGIGSDIIARFTKGPHDNEDDETDPGEAIFHPAILLLQILLDINPDADVAIVDDSLWCSKMEGRSVTVADVVKLVNSIIDACQIETVDGIVQFTENLEESTELSLKEKFQSYILFFFTGTTRTKTQQQALRKLKKLLSKPDPIPPAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQI3</accession>
    <name>A0A9P6EQI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQI3"/>
    <dbReference type="OrthoDB" id="3197614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130:SF1">
        <property type="entry name" value="SPINDLE POLE BODY-ASSOCIATED PROTEIN CUT12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="49514" checksum="4213BCD3F16714F8" modified="2023-09-13" version="1">MSALETPMNAAHQHAANADDYITQGLIVLAAEEHLKAAEAYTAAIDRSHDESAKRTLRMLYNEHCKAAKDLHRKIDKLKDEGADPALPHRPELPKASPQPILTNGNTRGGHKTMSGAPSPPPTHRPMAESTVGDESFMLLGGQRSDPGDAFNQFWNIMQGMLDNLSQPVAFATVPLGPDTPPQETPMAEKMASGHRRDGNLSSDTDPEEPIFSKFTRKIGLSNPGSKISERTSRNQKPTHSTKSKDDFSFEEDDDFFEEGDDLSGSFFLIPTGSEPSPAVLKKENATLKAEVASLKSRLDGTEKVLKLRKEQDVHLRDSIFQATREAQRALGASTMLQRPGPPLDLSSLNMNLPAVPIPGISPNREAQYNKRIKELEEELRLMKVENDKNKLMIAKFRERWEKLKDSAKRKKEAKAAAEVASTGVRDRIVEEPEAEEELDDRNARAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQW4</accession>
    <name>A0A9P6EQW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial distribution and morphology protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial inheritance component MDM10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MDM10</name>
        <name evidence="7" type="ORF">CPB83DRAFT_866632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion outer membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MDM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQW4"/>
    <dbReference type="OrthoDB" id="2103793at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03102">
        <property type="entry name" value="Mdm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027539">
        <property type="entry name" value="Mdm10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12519">
        <property type="entry name" value="MDM10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 6" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="47745" checksum="13A020FC5B6917AF" modified="2023-09-13" version="1">MHPFATYVLRNYYQATGWNDDNLFANITRSSNAILDFTVPRGLHISVAKSPNSLFKTSYSMTAMPSLNGSVGYIFTSCGLNIKSSGTVPFKDMIDRFLVYEQPRKPEAKEIEYLAGESITNRDYLLYGRLYLPTGRLDAVYSLRLSPTLQALVAAISDPPSPTPQDFRGRRSDPSNIMVSLQHDVGKWCTEYSWSAEDEMWGVKFLHNFGRLGHSTESADEAATRKRIGVKRVDEEEPVEGGLKGRVSVGAELYFSAKEKSAGLSTGIRFTTLPDATPPSAQLQTLSTPYRPAQPPTTITALFNPMLGHISSAYTARVSKDLALSSRFDFNVYSFESEWTVGAEWWLRRPSRLPIDHDSDNPIAVTALEPVPPLAVNGVVKARASTNNNVSLMWEGRLRNMLVSLGVVSDLSSRSKFIKALGLEVAYFSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERM1</accession>
    <name>A0A9P6ERM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERM1"/>
    <dbReference type="OrthoDB" id="3183767at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="792"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1201"/>
            <end position="1231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1244" mass="140927" checksum="B29220C108B5F0A5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESC4</accession>
    <name>A0A9P6ESC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_782639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESC4"/>
    <dbReference type="OrthoDB" id="195231at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="41057" checksum="BB75596C82DA307E" modified="2023-09-13" version="1" fragment="single">MFTRLLAQELPIPDVQTAPTALFPFIVGVTTVPISDSSSILSSTASASAAPSSSTSSFETFHFSSPLPDGVAKTASGKPIPCSPKNTKLNPSTHKLISECTAQAFCLAPPGSPPNATGLGVCVPRLCRRDMYPFGYGHFGGSNNPPKIIVKGKLVNNDTITLPPMCPEGLFCPDDGSGCRPRVTMGEKCELGRDEQCQTPVFDEQVPLESNRALCLNKKCIAATQNILQPCTIENTTYVSDISKGPGGGQFSSFVVRHNCLAPHLFCDPTALHPNGSGPTCQRTRRLGAQCTFDAQCDSLNCEDDVCTVPPDTPNTIAAWHWIATFLFILVVLTSTIITLAYVHRQQRYSNYHAVQEYYREQMGLRQSIMALHKAASRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESH8</accession>
    <name>A0A9P6ESH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESH8"/>
    <dbReference type="OrthoDB" id="3058101at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="413" mass="45066" checksum="8E6A81453BB8C679" modified="2023-09-13" version="1">MSDNGDRSSAPPHENPAPPDETITNKVVTLQKIIDDAVRDKTAFAIVANNLRAAGASVLEAQDYLDDFTSRSVGGSGGEGDGEREGEGEHPVPSGPRDAEANARAVEDAQWDLLLAKAAYARTKPSDFDPGISPAEFYKLLGGSSNSSSSTSIPTSVLDAAPHLRTLAAASTSDDHLSQTWKLRATYSGKDTIEGIVNLMQDLFVDFEKLFAAIDPAYDHHDDPKELSGEFVVVKKDQLTAKKALRTEADWIHVYLAWRSGVLLVYPHRKEELAEYAKIVGEVFRASPHDPANGIRFDDNSRRNYGHSPYHLNDRSRTMVTILGQLFRGTKRVNETPTSTSKAKRPTAICHNWNLNICREPCPNRRKHGYCSECGGKHRARDNTTCHAELQARLGEGSRKSTTEGAGGGSSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETE9</accession>
    <name>A0A9P6ETE9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_902433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETE9"/>
    <dbReference type="OrthoDB" id="2538345at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689:SF1">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="290" mass="35352" checksum="07339B8D05C442DD" modified="2023-09-13" version="1">MPRSRSRERERPSRTHYREPKEDRSRSRERSKSPERVRRSRSPTRKRRHASRSRSRSREHKRRHRSKSRSRERGDRKERRRRSRSFSSSSDSSQGSSHRKREKRHKRKGSRSRERRKEKRREKKERKDKKKKDTGTVPHWGKYGIISDTDIFTKDQEFRTWLVEERKINPETISKDQQKKEFSRFIEDFNTATLPHEKYYNMETYDRRMSALRQGEYLPPTDDLYDFNADLKAVSGAHKKKTVEQDSFMTKEQLQELRRVQQERNEIGRMKLLGMDVKTNFGVRMDSNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETN7</accession>
    <name>A0A9P6ETN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_888675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETN7"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818:SF3">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="276"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="975"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1189" mass="131242" checksum="C31483BF78644161" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETY2</accession>
    <name>A0A9P6ETY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_889062</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETY2"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="47"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="501"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9535147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="530" mass="59398" checksum="2EBAAE350AAD187F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU94</accession>
    <name>A0A9P6EU94_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_742353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU94"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6428" checksum="7CDF7D4DC4F5ECB9" modified="2023-09-13" version="1" fragment="single">QGSIFSAIGRGLNAIISAIANVIMTIISAITTVIVTIFDVIIDILCCNCFGSRRTRRRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV10</accession>
    <name>A0A9P6EV10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Amine oxidase</fullName>
            <ecNumber evidence="14">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_865811</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="13">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="13 14">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="14"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV10"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 14" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="16">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="17">
        <location>
            <begin position="152"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="15">
        <location>
            <begin position="344"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="12">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="13">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9535589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="794" mass="88133" checksum="42435EBB140F86F1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVG3</accession>
    <name>A0A9P6EVG3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_842190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVG3"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000015">
        <property type="entry name" value="Proteasome subunit alpha type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9535707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="242" mass="26859" checksum="B74C084A2522A690" modified="2023-09-13" version="1">MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTTVGIRTSEGVILAVEKRVQSPLLESNSIEKIMEIDRHLGCAMSGLTADARTMIDHARVTSQNHAFTYDEAIKVESVTQAVCDLALRFGESVHDEEAMMSRPFGVALLIAGIDELGPQLYHTDPSGTFVRYDAKAIGSGSEAAQSELQDKWHKSMTLREAQLLTLNVLKQVMEEKLDQHNVQLAQVTPKKGFEILDEVSLKEVIEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIW3</accession>
    <name>A0A9P6JIW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIW3"/>
    <dbReference type="OrthoDB" id="3232986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049233">
        <property type="entry name" value="DUF6830"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20722">
        <property type="entry name" value="DUF6830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="200"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="706" mass="79458" checksum="B8D1FBA0CE18CD70" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIX3</accession>
    <name>A0A9P6JIX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIX3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="36247" checksum="E4F532B1631381DF" modified="2023-09-13" version="1">MSVHCNCGEASCLIENYASASKKISSTCDFAARTSDPPFISVPSSLDYKVGDLCKWVQSWIGYGPVSLYMPEAPVGDPETRERAFWPDVKNLVPLDKEATLEDFDWTKTYAAPFQTKPVIIAVLPNYCLFYHLHRACWGSNHLFKEKILFENTGNVVSYLNYIDLGEYHELLGNFFKAIRSHIVVHPEYRETCEDLIENERNAKATLSIGLAERQPVAVCVPNNNVLAFTERGFTVKSADHGLALPRAVGAYWLLPTWDPRLDGVVQAFSGLKAVGQQRFCIELRENEWPSRHWAPPIYIGDNNKQEIMRRNLLQAFGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ28</accession>
    <name>A0A9P6JJ28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ZPR1 zinc-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_73205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a protein folding chaperone for elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ28"/>
    <dbReference type="OrthoDB" id="308464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000002">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="9">
        <location>
            <begin position="45"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="9">
        <location>
            <begin position="285"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9522886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="492" mass="54739" checksum="7BB035919A0A16B5" modified="2023-09-13" version="1">MAAQTNLFPNIGEIAEQTDQLETNADGVTSHDSADEDKVVQQIESLCMKCEEQGVTKLMLTSIPYFKEVIVMSFRCEHCGFSNNEIQSAGSIRAEGTVYTAKILERSDLNRQIVRSESCEIAIPELELTLPPTSRGQLTTLEGLIRDVVTDLSLDQPLRKIQQPEGYEKIQTIIDKIKDILADNGEEEAEFDGKPTVVKRAFEKDAPMKPFTVRLDDPSGNSFIEFIGSMADPKWNMRSYHRTLEQNVALGLIAADDEAVKNATMKEVAGQNDPISEDEIFVFPGICSSCGHAIQTRMKRVNVPYFKDILIMSTNCEFCGYRDNEVKSGSAISAKGKKITLKCEDRDDLSRDILKSETAGLSIPEIELVLTHGTLGGRFTTVEGILEQIYEELSEKSFLLGDASDKEDAAKMEKFFSGLKAVKNADRPFTIILDDPLANSYIQNLYAPDPDPNMVIELYDRSFEQNEDLGLNDIKVEGYEEGMKQKDEGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKG6</accession>
    <name>A0A9P6JKG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKG6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="54526" checksum="71CCD00DB428E759" modified="2023-09-13" version="1">MWTDIPVSRIVDSSWKAKGERGWDASIVDQLDTYLNRSSALPVHIFIDLWMTKPIPKSILHKILASFARKAYRWETAVILFDESRLPDLLSRWQNLQMPRLQRLNFRMRMICGYTRIIDEELPIIESLPPTLKELVLDGYSRHWGSGGTLGPGLESFTGLPYKLESLFKTASTLKSCNFRGIHIREMRLPHLNQRILFPSLTDLEVNEIRYSRTCVHFDDTHYFTTIFSHIDTPNLKKLVVNCGRTEMNCTQLLIGIFDAALASSWRLTSLSLNLHATFWIFVVGILKLLPTLRDLDIYDLSEMINFFSLSISSTNSTSFWDCNQKADPYRSTFSITTYLFIGWRKFLAKQLFYSEATSGAKFTALMRSTKQRKKPMATRTLDFKNISHVLGILELSDFLHDDNILESCLIELLDALATLPNDIILLKEADLRSRAAEGSRRLVERIRVNGHVWPHTWMPGENVCSLHSSQSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKV2</accession>
    <name>A0A9P6JKV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_798192</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKV2"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03467">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054716">
        <property type="entry name" value="Sol_Rieske_ferrdox_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782">
        <property type="entry name" value="SI:CH73-314G15.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22543">
        <property type="entry name" value="Rieske_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="43"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="495" mass="55510" checksum="4D3A8009E51A0DD3" modified="2023-09-13" version="1">MEYLEIAPLSQLLTHFRYHLNLRSQEGLYHALIIFRLSADTENTNIPSEQTPENIGEKQVSTEILSEDNGLVATHRQIYAMEASCPHLGADMSHAEIEECETSVIAVCPWHRYDFDLKTGESETGLRACTYAVEVRMDTERKMEKVFLESPKRGSSWQVVELRPVSEEFADPPPKTAPVLPVVPSAEPREPEPVVPDNGAPTTLIQWAVLILNTPNPILKVERTRHAVHQFRIGKLKAIGHKSSNTPSPPDVPPREASWTSNSVAPYKVKNNKNRASMLHALANIEQWAIDLAWDIIARFGPKHPDLPHAFFSDFSKMALDESKHFSLLTSRLAAISPSTPYGSMPVHASLWESAIVTSDSFRARLAIIHLVHEARGLDVNPATIQRFRKAGDHETVDVMEIIHADEVTHVTSGHRWFTWICVQQGGVDPVATFREEVKKGWKGDIKGPFNVEARERAGLTPHFYEDLRGELGDQEKANYQAPDKQVSVNIGYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLM9</accession>
    <name>A0A9P6JLM9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9525018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLM9"/>
    <dbReference type="OrthoDB" id="9985428at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF1">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014899">
        <property type="entry name" value="UCP014899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="41"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="345" mass="38411" checksum="3B630F3D2D97A857" modified="2023-09-13" version="1">MQRERQQKRSKPRQAKGNKPRQSAREPDKPRLTKPVLMNIAATTLEKIEQGSYDVGGQTYDLSKKVEQMKKGTLLYAPNSDLSSWRHRPSHSYEGLSSDVQAQDNVEISVNEVSTLAGTRILSEALTDIKHEQQNKIGVLNFASAKNPGGGFMTGAQAQEESIARSSTAYPSFMTPTAQPFYQSHRKDPKEGYYSHAMIYSPSVLLIRADHGDWLPPVEVDLLTSCAVNAGVVRRYLREANSEDESNLDAAMKERMARVLYLFEKQGVKNLVLGSFGTGVFRNRVELVATIWKELLVGDEARFARSFDRVVFAILGHDTYLTFERVFAEATLVEQNTTGGDASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN65</accession>
    <name>A0A9P6JN65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN65"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="25804" checksum="74131FBD81A56750" modified="2023-09-13" version="1">MNPTSLPSSVYSTKGEVLVNPEALSNLTTTLSSMPNSFLNDFNQLAAFSAANPPGPSSVETTLQQVLKELAAVKGELQSIRQEAICHKEHYPLSSQLYYPILGPAAELNTHYLSCHFNQRQIQKAWQNVPNITLQLSSCQTFFEHEVHDAPIRYIVGQPFWQDKANILCLPIMRGDIVDVSNIPPSSRYLKTFKFFVECSQQNENGYSLVRLAAYNEHGFCANTLDATYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNK4</accession>
    <name>A0A9P6JNK4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_769032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNK4"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="42889" checksum="0E4B38AA018EC03B" modified="2023-09-13" version="1">MTAVLLALPNPFTPMAFLPPELAVQATVSNYVLVGSLAVLTWDILSNLHSDLRLLREFRVNLSMTVYFISSRIFTLAYLSALVVLETAPTGHCENIRKIQAMYPIAVPSTSLLFFFRVCALYNHNRYLVAFFFISWLSVVAGAITTTQGITGGPIGLTKYCINTRLESYVSLACIPPFVNDTLVFCATTWALMQNSYADGSLRNGLKVMVFGRYLPSFSRAILQDGQVYYATIISLNLVVIVLFFTESVPIVYRSFFGVPNVVLMNVMACYVYRKIRFGVYRETTTLGLGNTTLGKSIPVSGGRTGARQERSGIVFNRVAINGRSAALTERSFKVEAQDERLDNVDEDGQLEVIQMDVVKTRHSEDGGSQFEIKMKPSDGNSCSTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNY8</accession>
    <name>A0A9P6JNY8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaminase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_371296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNY8"/>
    <dbReference type="OrthoDB" id="3918848at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032514">
        <property type="entry name" value="GtaA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033433">
        <property type="entry name" value="GtaA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF1">
        <property type="entry name" value="GLUTAMINASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17168">
        <property type="entry name" value="DUF5127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16335">
        <property type="entry name" value="GtaA_6_Hairpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040194072" description="Glutaminase A" evidence="1">
        <location>
            <begin position="24"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A N-terminal" evidence="3">
        <location>
            <begin position="102"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="2">
        <location>
            <begin position="339"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="67635" checksum="040C083589A28810" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPA0</accession>
    <name>A0A9P6JPA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPA0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="17690" checksum="D3261DFF0B95DDCC" modified="2023-09-13" version="1">MTSEFHPRVPTTASLQLRHTPSMGITNYQPFIITETPTKLFSGFHSGLPRCSKWQVPLHSRASFPFFSQQTHPPTIPTTTFPTTTLSSTRTISVPSLAASSFSFSCSRFYSPNRRRTTQKKNNLVLEANPFDVQTNHGVSLLCKVELSDYPAVTQTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPF1</accession>
    <name>A0A9P6JPF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPF1"/>
    <dbReference type="OrthoDB" id="2970175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="15803" checksum="4C052078596382EF" modified="2023-09-13" version="1">MAPLSSEERNMLVSNNTLFSEIVIVNKTLEAWPIVIRPTHRIRVIDVFRAIYDTYAIPLTREELARLGAERIQRSERAFLQRCQDSPESTHFLERQGMTRIDLLRGRRIFKGLIHHRGAPNHQFELIFDEGPPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQI1</accession>
    <name>A0A9P6JQI1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQI1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="55" mass="6145" checksum="80EB4D7B75819A85" modified="2023-09-13" version="1">MIKQGMAPLHSGFNLVDVLPILLLDPVSLLMYLLPNFLPNDLGQFQWGKHCSLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRI8</accession>
    <name>A0A9P6JRI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_852188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRI8"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="169"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="124"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="142"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="36554" checksum="970A7D8258135960" modified="2023-09-13" version="1">MSTKDHTLQSDLAKQKIQPDGSFKRPDSSFRNFIEKGGQFEPEKDRYHLYVALICPWATRTLIVRKLKGLEEIIPITIASPRMDTHGWPFASVDNFPGAENDPLYGSEHIKDLYLKADSDYDGRFTVPILWDKKTHTVVNNESSEIIRIFNSAFDDFLPDEKKAVNLYPEALRPEIDELNGWVYTDINNGVYRSGFASTQEAYSKAVKEVFDSLDKVEKILEGEKYLIGDKLTEADVRLFVTIIRFDTAYHGHFKCNIRTIRDGYPNIDRWLRNLYWKNPAFKDPTNFDHIKGGYYSMKSINPTGIVPAGPVPHIRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSA5</accession>
    <name>A0A9P6JSA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_788343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSA5"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="32"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="43413" checksum="29B46DFDDE60BD4A" modified="2023-09-13" version="1">MSFFIPAPAPKSKLGIYRLLSTNAGVHVSPFALGAMSIGDKWEPFGMGSMNKESSFELLDTYYNLGGNFIDTANAYQDESSEEFIGEWAEKRGIRDELFIATKYTTNFKREFDKPPFQKVMYIGNNAKSLKLSVEASLKKLRTHYIDLMYVHCYDWDTSIPEIMRSLHALIMAGTVLYLGISDTPAWVVSKANEYARCNGLTPFSVYQGAWNVMDRSFEREIIPMARAEGMALTPWNILAEGKIRTDEEEEQRRQTGEKGRTIMNPQWERTDEQKKVCKALEKVAKEVGIKSIQAVAIAYLMQKATYVFPLIGGRKVEHLLANIEALSISLSDAQIKFIEAQVPFDAGFPHWIVGDGSKLNDFWQFTTQVVSKPIAKPLRPDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU22</accession>
    <name>A0A9P6JU22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_735697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU22"/>
    <dbReference type="OrthoDB" id="3018897at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8712" checksum="FA44FEABF6D212A1" modified="2023-09-13" version="1" fragment="single">FDQTDFSASLPLKFSNIPWPTLRKPQHIRGEDIDCTSTEAFFKALKATVSSQDYQAIVKQSRRRFHPDRWRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUA3</accession>
    <name>A0A9P6JUA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_580351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUA3"/>
    <dbReference type="OrthoDB" id="4001642at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053060">
        <property type="entry name" value="Cytokinesis_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36419">
        <property type="entry name" value="ARRESTIN FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36419:SF1">
        <property type="entry name" value="RHO1 GEF LOCALIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="184"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="917"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="974"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="985" mass="103202" checksum="6C95CD2BC5FE261F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUG3</accession>
    <name>A0A9P6JUG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUG3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="93" mass="10517" checksum="89610173E8B2B5B3" modified="2023-09-13" version="1">MMSQSLLLTLALTLFLEFLSFLVSLCFARLHVHGVFVVADICFCFCFCLPMLVLVLVLLNHSAQFMTLIDLLRDIPSLHTPHPLLSHTVSHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUS2</accession>
    <name>A0A9P6JUS2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nonribosomal peptide synthetase 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_758066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
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                <consortium name="DOE Joint Genome Institute"/>
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                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUS2"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56261" checksum="CD624C6AE0379818" modified="2023-09-13" version="1">MSQLKEEIKSEKRVGEADITVQAVKPVDDHNGDSATSSQSSSQNSSKVDLSTEEGSLELSKNEHPWSGYENDVLPEKENGKAARNLRHQLFNLYRRLFSFIFIANLAIFIAFCVYGVNAQRLGTLVIANLFTSILMRQDHIINAWFFVFTLPRPSWPLWIRLLCARVYHIGGIHSGCGVSGTVWFILLVGQATREHVTTDKVSVATLVVAYIVLALLLSMIVLAHPDLRAKYHNSYELVHRFSGWSAVGVFWACFILLTNDYKPEGQSLAKTLRKSADFWLVVILTFSIASSWMRLRKYPVRAEVLSNHALRLHFEYVDPVPGSFTRLSDNPLFEWHSFATIAIPGEKGYSAIVSNAGDWTKKKIANPPTKLWIRGIPTNGVLRIVPMFRRMVIVATGSGIAPVMPHLLARKVPIKLLWTSPNVRETFGDKVVDMVLAAAPDAVIYDTRTHGKPDMVKLTYRVFKEYNAEAVAVISNPKLTYKLIYGLTSRGVPAFAPIFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVE1</accession>
    <name>A0A9P6JVE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_872291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family. PP-Z subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVE1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011159">
        <property type="entry name" value="PPPtase_PPZ/Ppq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000909">
        <property type="entry name" value="PPPtase_PPZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="255"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="455" mass="49699" checksum="E5918157589B2C71" modified="2023-09-13" version="1">MGQQNSKKSKKGSKDKDKDAPPEDQASSDTQHQDTSAESSSAARAVPTTNNDGSDPTLGNGTPAINVSDPTDQSAQNSGSDPSSPLSSPKPTSAPLDIPAAPTQTILSNGTASGSINSNGNGTPSESVSNGALKEKLKPFDVDDMIQRLLDVGYTGKVSKSLCLKNAEITAICLAARDVFLSQPTLIELSPPVKIVGDVHGQYSDLIRLFEMCGFPPAANYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCSIKTWKTFIDVFNCLPIAAIVASKIFCVHGGLSPSLHSMEDIKRIQRPTDVPDYGLLNDLLWSDPSDTALDWEDNERGVSFCFGKAIINEFLVRYDMDLICRAHMVVEDGYEFWNDRTLVTVFSAPNYCGEFDNYGACMSVSEDLLCAFELLKPLDGAALRKEMTKAKRKSLMASAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVK5</accession>
    <name>A0A9P6JVK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVK5"/>
    <dbReference type="OrthoDB" id="2561686at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7169" checksum="14CCA9951D99AFF6" modified="2023-09-13" version="1" fragment="single">MPSVAHAINNFVSSIVGIFISLFNSVFAIFHGVFALGVDLVNSVLTIVTHLFAMVGDLFQGVIGFVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWH8</accession>
    <name>A0A9P6JWH8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_802206</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWH8"/>
    <dbReference type="OrthoDB" id="73846at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="8">
        <location>
            <begin position="253"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="410" mass="45264" checksum="3B11C144C46C28B6" modified="2023-09-13" version="1">MHFHILGIGSIGSLVAHHLRRVLPIGHSIGLIHKTNQDRERLLQKGSLSLERAGATDESRGFHHEVYHEDSISPTPPPGSPPPLPTPPSETVVKDASKIPIDSLLVTLKAHQTVHAIKVLGPRISSNSTIVLLQNGMGVYEKLLKEVFLNPSQRPHFILASNTHGAYATGFHKVVHAGVGAIDLGIAPDSQGRDFEAGMYDNEIDPRNRQLRLSDLSPSGDQHASRYRSLRATIAALLLLEPLNTSWKPFYDVQVNIRRKLAVNAVINPLTALLDCRNGDIHDHQPARALMKQICDEASAVYEAQMTAETQTWLAELKAQGIKTMGVPLPPFPEALTSQSLQDEVLRVAAITRRNISSTLQDVRKGRHTEIMYINGYLRELGIEYDVPTPVNTTLADLIHMKYLLPLNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWI5</accession>
    <name>A0A9P6JWI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_29031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWI5"/>
    <dbReference type="OrthoDB" id="1661054at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="689" mass="75057" checksum="2F2C5432CE5EB8D0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWX5</accession>
    <name>A0A9P6JWX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sec20-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_878747</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEC20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWX5"/>
    <dbReference type="OrthoDB" id="46868at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005606">
        <property type="entry name" value="Sec20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825">
        <property type="entry name" value="BNIP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825:SF0">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SEC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Sec20 C-terminal" evidence="12">
        <location>
            <begin position="146"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9535608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="37903" checksum="9113FA26576B5533" modified="2023-09-13" version="1">MPPIPSRLPQETLSLISAAERRYKHVNEVGIPNLHKCTGPLKAQQMLSEEIRDDTVLLTQQIEELEMTVDDLSGEKNRRDLKGIVDDFKSKLDRLRRDTRTALLASKRVIDSKSKSNRDELLATSSISEKQTSSEKTTEDVLMKANSDVTDALRRTVALMQSELEKSVLSTQLLDSSTKSLESTSFQHDALSSVMTTSKHLITALEKSDWLDKLLILSAFSFFILVVLFIVKQRIVDKSIRIAFWWTRFIPSFGDDAALLSETEKGTAGAVAEVSSVIASVTTSLAVPVSSIISSVLSSSTLSQATSLGGASPEASPSPTDSPISSVLEGSLVPNPIPPADPLVHVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX44</accession>
    <name>A0A9P6JX44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_754215</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RRP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX44"/>
    <dbReference type="OrthoDB" id="448446at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 9" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9535430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="335" mass="38329" checksum="4AAB619CFB7CE5C6" modified="2023-09-13" version="1">MPRRPRPALRNRTFKEKDPLASHVKLQHPKPSKSIQPILPTSSKRKVESNLESENEFEEGSSQYSASDSGSQTDAEDEEDNQSDVDAPRVALWEEDNEDFLEESDDEDGVAKVPDEKALESNLQDLPLGALRRAQTLLRRAEPETDSGSSDDHSTDDEAPETLDVKGKARERVEWSTKPRSDLAKRSNKHAPTEMSAKRPVSRKRIVVDVPKIVSRDPRFLPTTGTYDPTKFQQSYAFLSNNRKSELQTLKETLKKARKVLSSSPRDVRFEREQEIERLERAVKRAESNVNRDRLDQVEREALSGVKKTEKEKQNQGKAEWFLKKGLSYRSKKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC71</accession>
    <name>A0A9P6BC71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_932324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158133">
        <property type="protein sequence ID" value="KAF9521315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC71"/>
    <dbReference type="OrthoDB" id="2433298at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9729" checksum="B1641EFED16A8488" modified="2023-09-13" version="1">MSPNQALISLHADHIGGHNANYRKWYFAAQLDLDDAIGQTQNPGVRRLKSVKGGKRNPHEKSLATALDRWREAVNSMSQIIGYDDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E319</accession>
    <name>A0A9P6E319_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158020">
        <property type="protein sequence ID" value="KAF9521590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E319"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="15646" checksum="CEE7BDBAF548B168" modified="2023-09-13" version="1">MKVFERDESNFKLYQCWWDVLRHAKGGALWGFMGHTPSFCALIEKASRATRDFSTEDAALPDDDVIEHVLTCGKSIITPGDLWRNCRWNLAFGNDDNIAEHGQMLLDKLSEVYANYDDLDSSEDERPPVASPPAIRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E379</accession>
    <name>A0A9P6E379_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2 small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2A</fullName>
            <shortName evidence="5">MOCS2A</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfur carrier protein MOCS2A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_865348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaD family. MOCS2A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158003">
        <property type="protein sequence ID" value="KAF9521682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E379"/>
    <dbReference type="OrthoDB" id="5595860at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990133">
        <property type="term" value="C:molybdopterin adenylyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03051">
        <property type="entry name" value="MOCS2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028887">
        <property type="entry name" value="MOCS2A_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="1-thioglycine; alternate" evidence="5">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycyl adenylate; alternate" evidence="5">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9521682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="90" mass="9592" checksum="3234B4090B8B845D" modified="2023-09-13" version="1">MSQPKTISVLYFAAASTATGKSEEMVVLPNGDFKLSQLTQLLVSRHPNTNLDSILKTSQWSVDLEMVDDPNSIVLKGGEEVGVICPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3D0</accession>
    <name>A0A9P6E3D0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_778169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157992">
        <property type="protein sequence ID" value="KAF9521757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3D0"/>
    <dbReference type="OrthoDB" id="5535068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="121" mass="13591" checksum="F5C383F3D95A223B" modified="2023-09-13" version="1" fragment="single">MQHDSPNSPERSKSQVLSRLLDGKITIDVRELLATLKEISHALTEAIRPKNVSQLQEMQRPREVMNTQLLITRAPPHRRLIKWQVTIQDTPVTAVIDTGSEVNLISEHIASQVIGLPLDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3H1</accession>
    <name>A0A9P6E3H1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157982">
        <property type="protein sequence ID" value="KAF9521843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3H1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="17805" checksum="E175D7E2C2C4C7BF" modified="2023-09-13" version="1">MLREMTRNVGWANKESWRSKEANASNTRLKSNDGTGKLTIKQQMEYPNAEESINDFLETSGKKRTVELGNGDGESDREINDDDDEDDDCSVANHDTRISFWWKRRGQRWSRRFNIEWMSGRRFVQHYRLFNTTPNVEFNLVEAFVVVVRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3W7</accession>
    <name>A0A9P6E3W7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_777614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157962">
        <property type="protein sequence ID" value="KAF9522083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3W7"/>
    <dbReference type="OrthoDB" id="2860915at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="19991" checksum="44B3AE7E304429D5" modified="2023-09-13" version="1" fragment="single">KRRSAYGQEEKVKKIFAYMAEAFPRFSLRDFLETAFRSVDPKITNWTHIFLADNSYLPLMDVWWEKSGGLKPTRRDSAMCHWIVNHATEICSKEASWLTDDAYNGPHTLDAKNLRIKSPTVTVSMVEEFKIYQLLSCYERTTPYLQQILKGIIAKDPTDLKEGSRNPHAVSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E489</accession>
    <name>A0A9P6E489_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_919332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157956">
        <property type="protein sequence ID" value="KAF9522205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E489"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016899">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="487" mass="53873" checksum="68106F67F34814BD" modified="2023-09-13" version="1" fragment="single">PYNTFDGPGFPACRDVAAVYEPNTIDEAVAIVKNASSHGIPVRASGNGHMWYDTMCSDDPRTIIVRTENLNRISDLVLDGAKGSVVVEGGVTFPQVAEWLHARGASLGYTLVNWNISLGGAMAMGAHRSSLGADSQLSQLGVVPLTNRLAGELIHLERDQSNDSWLAATTSLGLLGIIARAKIEILADFKVSANQETIEEADLLKADIYTEISPYVTANYWWWPGQKKFHKRTYAVVPITTGGDAFQSTFSISGTDANTAMNGLNLGQNISVQNFLMESIFYTLWRTPNFHSKKTNFQLFSWPVIGYAYDVLIGGLYPNMKTEWDYGLRGLTFEVAVPVTQANKLLTRIRKLFDEAAADNKAVTATYRSGINIKFGRPFDSLLGQTTTLQSNKTADWSKGAIMFDFPSFRPSTGDHTRYNEPYSTMQKTIINEFPTRTHWTKCTRDILSHSVKNLDPALLKRFAVVRQKFDPQGTFKSVVGEIIGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4E6</accession>
    <name>A0A9P6E4E6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_777263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157951">
        <property type="protein sequence ID" value="KAF9522307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4E6"/>
    <dbReference type="OrthoDB" id="3060595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="16465" checksum="5E529F186F6A1D94" modified="2023-09-13" version="1" fragment="single">METRFYVTGLGKQKVILGFPWLTDQNPDIDWRKGTLRWRDFGYLKRLKSQIIETEEEDLSLVVSYIHGEHDENAEEIWINAKTTHSQLLAQKFDEKNTGKSLEELVPQEFLDYRKVFSEEEASRFPESKKWDHKIEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4P4</accession>
    <name>A0A9P6E4P4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_822857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157946">
        <property type="protein sequence ID" value="KAF9522430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4P4"/>
    <dbReference type="OrthoDB" id="3253907at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="40335" checksum="F46B018714E1738B" modified="2023-09-13" version="1">MVESLTKWRHKYEDRGWLNIGNSNEIKTTIARLLERKAPTTLQWVKGHSGLAGNEGADKAAEAGRTKPANSDDINTEIRRSLGLPGAKLRTLTQGSAYRAIREIRMKEPRHKISIERPSTLRNMKTAMEGATSLTGRNLSDKQIWVSLAHKDFSKKIRNFMWTIMHDGYKIGHFWSHLAGYEERGICKSCHAEESIEHVLTKCNAPGQKEIWDLAGEIWEQRNTEWIRPGMGEILACGTTDLKDADGKPWKGDSRLYRILISESAHLIWKLRNGRVINNEANKSKREIENRWRAALNSRLRLDCLMVNSKYGSRSNKAQVVKRTWLDSLQDKQSLPEDWIWRAGVLVGSRAGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E539</accession>
    <name>A0A9P6E539_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_91712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E539"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="16770" checksum="196627351CCF3E18" modified="2023-09-13" version="1">MNSRADGSLHTFTPAAIPTSLTRISFVVVAGSTGDPYIRVLVASNSGETLTLRRLRVSRIFDLPEKYIQLIEPVRSLIGVRVMLDMMYGTQWSVRLCSNSSSYIAANSLLVSPQASGFEDNSGINDEIMEMAPRQVAPGTLVQQRVTGCRRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E574</accession>
    <name>A0A9P6E574_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_88420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E574"/>
    <dbReference type="OrthoDB" id="61113at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="63"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="233" mass="26677" checksum="85B9A05E155BFA26" modified="2023-09-13" version="1">MVGKGKIHRIYTPSVQEIEKLVNIAVGAYRGLTAERVMLGGNEALGYLQFRSMIRASLLDGEVYVLENDAKDLVAFSIWFPPGKVLYGTPDQRSLGFEEFMEQLDDETREWYDKTYNPAINKWAPTWIPKPYPDCWWLAALATDPVHQRKGYGTLLLKHAIQMIPASNVLGLVSTLEETVHRSFGRSFCSDHYIFIQARFYVHAGIPIQSRMDPDLPSKFGEIPFYGHYREQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E598</accession>
    <name>A0A9P6E598_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polysaccharide lyase family 8 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_871870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E598"/>
    <dbReference type="OrthoDB" id="5980780at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016837">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on polysaccharides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="entry name" value="Polysaccharide lyase family 8-like, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004103">
        <property type="entry name" value="Lyase_8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="HYALURONATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481:SF1">
        <property type="entry name" value="HYALURONATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02884">
        <property type="entry name" value="Lyase_8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="Hyaluronate lyase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040115717" evidence="5">
        <location>
            <begin position="28"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 8 N-terminal alpha-helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase family 8 central" evidence="6">
        <location>
            <begin position="404"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase family 8 C-terminal" evidence="7">
        <location>
            <begin position="690"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="753"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="806" mass="87191" checksum="AE2D471C5AE13E54" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5G8</accession>
    <name>A0A9P6E5G8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_822421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5G8"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8814" checksum="7542B47BC051FE10" modified="2023-09-13" version="1">MIIPVRCFTCGKVIGDKWNTYLDLLARDMSEGDALDELQLKRYCCRRMVLTHVDLIEKLLHYNPMERTKDKVNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E792</accession>
    <name>A0A9P6E792_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_910475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E792"/>
    <dbReference type="OrthoDB" id="2803783at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="676" mass="73489" checksum="E690F4B4755FFABB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7B5</accession>
    <name>A0A9P6E7B5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9523991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7B5"/>
    <dbReference type="OrthoDB" id="3344950at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="152" mass="17064" checksum="F4F6176814CDF5E9" modified="2023-09-13" version="1">MSSSEQLNFNAPHAPQSNAIEAFNIILSTIKQEVIKSRNDWDKHEPRMWSRATGLSDAELTSFSIEKDLVEVRSAATTYGTIILGKIRLPAVQDGAGEGFLHVRIHDPPNRGAEDIIFHSLFTDEIRDEPNSQPIGYCAIQTVEKPLRFFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8B6</accession>
    <name>A0A9P6E8B6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_897990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8B6"/>
    <dbReference type="OrthoDB" id="3265526at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="3">
        <location>
            <begin position="160"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="37739" checksum="263DB0A5D500D8FA" modified="2023-09-13" version="1">MPSVKLQFGPMLLGVMMNMVLYGVLIVQCYHYYQTYKKDAPWIKLLVLYLFVVESINTGCDIYIIYQPLIERFGSPDAQKYFPTLFAAEPITIVAISTPIQLFFAWRIWVLTKSKALSGVICSLALASFGKFYYLTSDRRSLFARKAELHTPALVWFLTACCADVLITVTLVFTLQSKKTGFVATDDAISRIIRMTVQTGMITAICAIGDVVFFMTLPKTALNFLWDLALAKLYANCLLSTLNARASLADSSRSSSNYLSSQGRQMVSGGPVRMRTDASYGAEPMSPHIISNPMYELEEQKTYADHNSDVEYGITITKVVETRQDMAPHNRRDHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8E6</accession>
    <name>A0A9P6E8E6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_774194</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8E6"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9524244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="506" mass="57061" checksum="9CDB20521D29A512" modified="2023-09-13" version="1">MTSNGITLDLTTAAWWLLGLVLTYYLYHCNRSPQLPPGPRRLPLLGNAHQLPSETPWVVFGEWAKTYGNLIHVDLFGQSIIIINSRKIAFELLDKRSTIYSDRPIIVRRFTELGDNLVFQPYNNVWKKQRKMIAQDLATAGVVQFQTLQEREWRLQVKNTLKKPDTIFSEIKWRAGVIAMRALYGYYVRTPDDPLLSTPLKTMREFSRLSTPQASLAFRFLPRWTPGVKFLQDAANFNQLHVASASAPYEWCKNNLKTGDILMPNVCCNVWEKSPCLDDYEHNQIYNALAGAFGGALDSNASSALTFYMNMILHPEVQRKGQAEIDAVVGSGRLPSISDQPNLPYVRAILAETLRFMPAVPLCIPHALKEDDIYDGYHLPKGAWVLPNIWHMLRDPKIYPDPMNFNPDRYGGDDEAMEQVKTPVFGFGRRGCPGRLFAENSLFALLATTLATCNISPGLDDNGREVLPSGEYTSGTISFPEPFQITIKPRSAIAEALLADITEVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8K7</accession>
    <name>A0A9P6E8K7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8K7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="317" mass="36049" checksum="E0E855F410A5D70F" modified="2023-09-13" version="1">MNQGLPKFLSAMGFVKHHDLEQPMETYRAHSTPTWWGGRPPSSTRRLRLVGVEMVEPKPLARTNCNLTGVQTTESTNFHKMYENVFQEELKTMTPDIRRTLFRGCSTPRNSGDDTSTLCGSEIQPEILTDSYLRVRLLDTEANQPLFLRAQRVRPESTKSLKEIRDPYYELRGSSPRDRFLPFDGILQNSECVSMTLILPSDYDQSGPNFYFADVGLAASAITWASKKFSIVEPDAQQYWFCYLMMMVLSLSLNCEIIEHGLDDTRGKVKVCGTGHWGQTQRRIRELETNLERNWGRADCAAKSLSDDELCKGGEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8W5</accession>
    <name>A0A9P6E8W5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_605493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8W5"/>
    <dbReference type="OrthoDB" id="3257061at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="1">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="14662" checksum="1A2C6C39216D1A59" modified="2023-09-13" version="1">MVDGLLMPPHSSVLAATIGITFVTPHKVVNRDLQGLFRVKRERVRDALKWLQANNQLYSDIIISEDRLSELPEDDVPTEIVSTTRVSADVEAVLREEEGYVPLDVLDEGEFHAERLSRSQISHICYRPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E982</accession>
    <name>A0A9P6E982_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]</fullName>
            <ecNumber evidence="10">1.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Saccharopine reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_594759</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-saccharopine + NADP(+) + H2O = (S)-2-amino-6-oxohexanoate + L-glutamate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.10" evidence="10"/>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E982"/>
    <dbReference type="OrthoDB" id="10059875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004755">
        <property type="term" value="F:saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1870.10:FF:000002">
        <property type="entry name" value="Saccharopine dehydrogenase Lys9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="15">
        <location>
            <begin position="20"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00066976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9524772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="762" mass="84030" checksum="98A643655AA4E939" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9V8</accession>
    <name>A0A9P6E9V8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_860154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9V8"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040317047" evidence="3">
        <location>
            <begin position="21"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="4">
        <location>
            <begin position="27"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="392" mass="41178" checksum="35AB28DD37D54244" modified="2023-09-13" version="1">MHSFTGLLALAASLPAFTSAVTFNLVDDYSGKTFFDNWDFYGNYDNLTNGDTTWVTKANATSKNLAEINSAGNAVLKVSTDTVVWNEKRDAVRITTQKAYPLGTIWITDVVHLPYGCSVWPAIWTLGQNTQNWPNDGEIDILEGINLNTNNQMALHTAPGCMHSTSVTQGGKSLQANCSVDAGCTVQDPDPKSYGNAFNQAGGGVWATQFTKETLVSIWFWSRANIPASVTKLASSKDAITSQDDWGTPTANYPGGSDCDLTKSFTAQKLVYDITLCGTWGGNPDFYLPQCSAQGPTTGAAACYTDNVVGNGSNYANAYFEIKYLRAYIDPSAPAVPGQNTSSSGGSSSSNSSASGSSGKAGAGVAAAPPITMAFLSSVAAIVIGAAFASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA20</accession>
    <name>A0A9P6EA20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_796775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA20"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1300.10:FF:000003">
        <property type="entry name" value="Amidase signature enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF10">
        <property type="entry name" value="ACETAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="61"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9525240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="61224" checksum="FAED60C352D0DB40" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAH4</accession>
    <name>A0A9P6EAH4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_908890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAH4"/>
    <dbReference type="OrthoDB" id="3218112at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="27"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="317" mass="36043" checksum="6DA0A2A0785C7EEE" modified="2023-09-13" version="1">MASPVASAHASLDGGISRHPDYYFTDGSVVLIVESTALRIHQSILGRHSDVFSGMWDVPQPTSMESYDGCPTVVLPDSLDDFVDVVSVLYDPFLHSHFDKLDSQTNLKELISFISGILRISTKYNMQQIRAKCISIIQDKFPSTLAGCDDVLKRKLQYRPSEIDRIIPLARETNVPRVLPWAFYLCAQMAVSELLQNAALSWKDKALCLAGKERLWEMQKTVTHTFLLNFQNSPQCITGCKVRSPDTFKAAMDAIEVLRLTPHALEEYTDWPGLRLCIKCQIYVQTLHREGREKVWQLLPTFFHLGTWDEIFKDQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBW4</accession>
    <name>A0A9P6EBW4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent DNA ligase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_896582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBW4"/>
    <dbReference type="OrthoDB" id="7482721at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF2">
        <property type="entry name" value="ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="6">
        <location>
            <begin position="413"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="878" mass="99727" checksum="B4814F5FDEF3BA31" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC00</accession>
    <name>A0A9P6EC00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_858074</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC00"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="10"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="345"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="426"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9526260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="600" mass="68597" checksum="0C8D87243E626D36" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECB8</accession>
    <name>A0A9P6ECB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_770244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECB8"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040136541" evidence="1">
        <location>
            <begin position="22"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="64"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="396" mass="43953" checksum="5614909137C56331" modified="2023-09-13" version="1">MFVSVLFSLGIFFSERSLSLALPNVQSDSSRAIFSSVTGILESTKSRTRSLSERGSINYNPDGTPFLWLPQDEYSGTSFYDRWNFFNHPDPTNFLDKKTAFDKALVSIDKDGTAIMKADDFTSLERGKFRDSIRIESIDKYTTGLFVLDLKRAPWGCAVWPAFWTVGSDWPWNGEIDIIEGVHDNEHNQVAWHTAPDCNINTTVGFSGSVTQAGGKAHTDCNAFIKSNAGCSITEWSRASYGPYFDSQGGGVFVMKWDENDISIWSFFRAAVPKDIIAGQPNPSLWGVPSARLHSSQCSINKFFKDHSIIFDITFCGDWAGNSYATSGCPDTCEDRLMNPKNFENATWSINSLKVYRKQVLAKGFTQVVSSAPGAYSKLPTWGVLFVGGFVICSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECC6</accession>
    <name>A0A9P6ECC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_896021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECC6"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="453" mass="50182" checksum="393398241B647A62" modified="2023-09-13" version="1">MSQQRPNATRWIVIDDTSPEISYVGPSGSWFDTEGVTSFFTRNDSGGLLNSNGLVYNATQHGTRLNSSFLFNYTGYEFLVGGTIENGYRDKGELWWNCYRDGNEVQNHMDLFNITTVPSDNNWFICGDWQTGGSDDGQHTLTVNISATKELPFWFDWLRYAPLPDVSTENKVVQLDVDDPSILASLSSGWDTGMSETKTKGASFNFEFTGTSFIWYGLARLDHVDPPTNNLTVGTYSIDHGPQHPINFPIVPSRGHWFNQKFFDTGTLPMAKHNISVIYTYDGTLPLGLGYVRIQNGSLSQPVAVSSSVQEVRSKRTTIILSSVIPIIVLVIVVCAGWFIRDYLIKKRRQISPRYEIDQQGTVESQFASTASVHPYPTTVTQSDPSSPNIKTTLFSSAYNISPSGSRRPDGRTDSSRGDAVSMSVREESSSVGLGRNATYRSGVSDAPPVYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECU6</accession>
    <name>A0A9P6ECU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_769743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECU6"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="200" mass="22875" checksum="53BD6A032CB162E1" modified="2023-09-13" version="1" fragment="single">MAEKKSHASCPNHRRHPASLSLICEHDPRLVVLMKKRVSMEMVNYVAREASRVIRIEGESDSEPSSTSDTSQSKRDSLSIPVIPPLVSLERFIVRLVKSSNVQVSTLLTTLVYLERLRTRLPTLAKGMPCTRHRVFLATLIVTAKYLNDSSPKNTHWSNYAVLFDVEEVNLMEKQLLYLLDYDLRFDEEEVCRLVAPFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDA1</accession>
    <name>A0A9P6EDA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF726-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_856902</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDA1"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF22">
        <property type="entry name" value="DUF726 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9526972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="559" mass="60435" checksum="AECF5DCD7E4AC894" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDL3</accession>
    <name>A0A9P6EDL3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase family 25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDL3"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="2">
        <location>
            <begin position="67"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="43486" checksum="3D67B4969793BEC9" modified="2023-09-13" version="1">MLLDSRPTDSSRRSFFKRVYLLSLIITVVILISYVLYLDPRPRFSGILELSTPWKSKSKSKFFGVIDKIYVISLPTRQDRRTEMEKLRKGLGVEWAYIDAFPATEPMVNSIKGKVVSTRASASQTHSQFKWPEISEELVHSKENIELWQDDSWYPSPDPPPTSLPLVQCTQKDYDMISDPRTLPEHLILTPGRVACWRSHIEVIHQIANDDAEATLIMEDDVDVERDLEGHLKRIWPSLPKDWDSVYLGHCWSNETFWPALPAVSTDPSVSFKPSILNSSLPTLHPSQGPKCNHGYVLSRTGARRILLHLRYPLFAYSRAVDQALAWMIESRRTKSFSVFPNIIAQRKVSKSDIMVLDGVENAGWKDFLVDGFFGDNKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE84</accession>
    <name>A0A9P6EE84_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_934369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2"/>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE84"/>
    <dbReference type="OrthoDB" id="2108802at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004352">
        <property type="entry name" value="GH114_TIM-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35273">
        <property type="entry name" value="ALPHA-1,4 POLYGALACTOSAMINIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G07890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35273:SF2">
        <property type="entry name" value="ALPHA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03537">
        <property type="entry name" value="Glyco_hydro_114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040345282" description="alpha-galactosidase" evidence="4">
        <location>
            <begin position="21"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside-hydrolase family GH114 TIM-barrel" evidence="5">
        <location>
            <begin position="63"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="34944" checksum="65E51DAE02F95EF6" modified="2023-09-13" version="1">MHKTLFIALTLGAIFSAAKPAHNKPPCSKTKSETHSSTSTSPPSSSTNSLATDSFWKPSVGQSWQIVLSGVVNTKVDLVPNVDIFDIDGQSHSQQDIAALHSKGKKVICYFSAGTVEEGRPDVGSIEQYTGKVLPAWPKEKWVDVRVQAVRDVMANRIADFATKGCDALDPDNVDAYNNDNGLNNFQKDDSIDYIKWLSTEAAKHNIHIGLKNAGEIIPSVIDSVAFSVNEECNQINECQVWEAFPNAGKPVFNVEYIDGGDNGSSRRDVGPVRRVDWKRDGGPVGQCPGTNGFSSVVKKLSLDGWVRFCDETEETTALVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEP2</accession>
    <name>A0A9P6EEP2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_814378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEP2"/>
    <dbReference type="OrthoDB" id="121380at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040225364" evidence="1">
        <location>
            <begin position="19"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="2">
        <location>
            <begin position="101"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="314" mass="34021" checksum="65460D0566919BCF" modified="2023-09-13" version="1">MKLYILFSLVAIASTVLAHPEPEPELTASEIVKRELEARNREWKARNCQAEIRAFTADRVAKRDAKLGRRQNPSGTEITAAAHVTGIPDSATCIVAPEVTEGPYYINNELVRQNLTETQGGVDIVLDIGVIDINTCQPIPDAFVELWAANATGVYGGYSGASNAVKKETFGRGGYATDSTGVVEITTIYPGFYTGRTAHIHTMIHLNYTKNTDGTIKSSSGSNVHVGQFFFDETWNDRVYATSPYTLNKQRRTLNAQDGILKDAGSNGYNTYASLSYLSGSGLPQGLLGYITVGVDSKAHYSISNKNFYGGSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFK2</accession>
    <name>A0A9P6EFK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFK2"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="105" mass="12826" checksum="863A1D93AE4BDBC7" modified="2023-09-13" version="1">MMHQLKCLDLLREEVVRDRPTVSHEFKSTVQIAPVTRHCLNYIRQMIICRGDWELESFQFASHKNPIEWRGQYQCKDWERLWHFVKKNQEEYEGWLETEGAEEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG67</accession>
    <name>A0A9P6EG67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_854461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG67"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="71"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="325" mass="35466" checksum="CB1DFC45DE891DC5" modified="2023-09-13" version="1">MFYQPHRLGHPPRVFRQTISLVSSAPLTRALPSGLPSLTLHSTNRRSSTKSKSSTENRIMTTSKLIVTFIRHGQSEDNVKSIWAGWKDAPLSELGNKQAAALGRSLSSTHLTHIYASPLLRAHQTAQHVLSFQAEPKPPLTLNPNIREQKFGIAEGHGWTLQPPQGVPLEKLYADGLYPVLYGREEKFPGGESLNDLRERARKGLRESVLSHLNEVQGGADVHIALASHGLCIGELVAELVSLDTEAKDQRGYTGLMNTAWTRAEVKVRDGHGGPIDPINPPSLEVKITHVNEKAHLDALKDIPPVEDVGGSQAEAKAFFGGARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGC2</accession>
    <name>A0A9P6EGC2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGC2"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="894" mass="101281" checksum="620F5178EEDC6C17" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH15</accession>
    <name>A0A9P6EH15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_813238</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH15"/>
    <dbReference type="OrthoDB" id="28092at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040383153" description="ER membrane protein complex subunit 1" evidence="12">
        <location>
            <begin position="21"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="980"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="14">
        <location>
            <begin position="20"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="790"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9528732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1009" mass="111131" checksum="99BB7A502D19AD35" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH78</accession>
    <name>A0A9P6EH78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_853592</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH78"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="422" mass="47102" checksum="95D742A4C7BC12E9" modified="2023-09-13" version="1">MLSKDMSRVDLLVVLASMGVVLPKETKLPLEELGKRLGSALDASQEMAALLGSPPVNLDLLFKWASNPGKTLFKASQRGNFTELTTGEMEQPKKGPGALKSDTFKELRQSVLALSYSFDHNIRQTSFVCQQIKSAIALRILEVYRVKDEVPLFFLEFKDLVSSAKEDLENLTNAFFPSGDLNTIEVSHLEYCAILKLFKRNSTKLADKHRSDTGGLGKKKGSTKTFVLPLCPLSMQVLGKLTSDVGCEICGEKIASKCSQCLTVSYCGKECQRLDWPNHKATCKSLKGGSWHPIDLFDMPELPPGVGDQAKHRFVMNRLDPFTSSSGLHSTTGDDAPDSHRGKIFLAKFQAPLMGGVNPSMMIYDRQRSFQSFWRKNSNLETFNQAMRVMGGRPKFYKWVRWVGENKMEICLDRSPASDPVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHB6</accession>
    <name>A0A9P6EHB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidyl-Lys metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_835305</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHB6"/>
    <dbReference type="OrthoDB" id="412874at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050414">
        <property type="entry name" value="Fungal_M35_metalloproteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016:SF3">
        <property type="entry name" value="NEUTRAL PROTEASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040191420" evidence="8">
        <location>
            <begin position="22"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Lysine-specific metallo-endopeptidase" evidence="9">
        <location>
            <begin position="207"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="37462" checksum="F94F3B82C9160178" modified="2023-09-13" version="1">MIAKTISASLIFLASLTVAVAERALSLRTAGPSSVNSVGSLKVVVTLTNTGDETLKILNDPNGPLSRLPTDTFIIADKTGSTPNFSGVKAKYAPKIAAAGEAFTTLAPGDSVDVEHDLSRAYDFTASGTGTYKIHPNNLFYLVNEDSSIKSIYADTQSSYSAKLSGRLAISRPSVKRATFNGCSASQQTIVNTTTVVAQSYANSTYAYLKKLTKATPRFKSWFGPFTASSNKTVSTVFSKISAEKFSTFQYDCTCPDPDADEGTFAFVYPDSFGTIYLCQAFWDAPLNGTNSKGGTLIHEATHFTVNGGTDDLFYGQTDARSNAITHPDQTLMNADNYEFFAENHPTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHE2</accession>
    <name>A0A9P6EHE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_283966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHE2"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="149" mass="17240" checksum="DD104BD6921643DB" modified="2023-09-13" version="1">MVLLILNPITPMTGHLQFKIPIKSSTPFLWAAQVLDRQLSFLRISPEDIRKNLTKIFENLRKSPLPIRTKQSYGLLDEGYLRSFIFAGLFLPYTMFPTLGRGLASLAGGEGRQLFLRPPPFKCHCKPKDVFYYFRILQQLWSVTTEITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHM6</accession>
    <name>A0A9P6EHM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_852969</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHM6"/>
    <dbReference type="OrthoDB" id="1284551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045159">
        <property type="entry name" value="DCAF7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19919">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="311"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="424" mass="45745" checksum="62922B86316AD497" modified="2023-09-13" version="1" fragment="single">MTQTTLLNYEAPWPVHSLDWCKSSAPGQQLRPRSAFRLGVASFVENYQNQIAVVGLQDERVLVEDDFADYPDFVTLCEAYHGYPATSLQWQPASAQSFAWSQKSPSTELLATTGDALRVFEYSGDGLPSASSYIGRPAPVSSGHSLSLKTVLSGQSKVQNQSGGAPLTNFSWNEKSPNLIVTASIDTTCTVWNIDTSTAMTQLIAHDREVYDVAWLPNSTNIFVSVGADGSLRAFDLRSLEHSTILYETPAPKNVPPPPPNPSSSARPPTSPLLRIAFNPSDQNYMSTFHMDGNDIQILDMRSPGQPVIELRGHHAPINALGWGSTERPLLATAGDDCQVLLWDLAGHTTGASSPRSAGSRLNSPRPDAKKKVVTEPVMAYTASGQITNLAWSPQIPGMTMNTGYSTATGEWLAIASGKVVKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI43</accession>
    <name>A0A9P6EI43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI43"/>
    <dbReference type="OrthoDB" id="2802356at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="438" mass="47567" checksum="9C01C65DEB8C6DFC" modified="2023-09-13" version="1">MWNPNTTITFLPHTPIMAYSYYQSSGQPGWGTSQFQFGRPPTPGFQPQPGWGGNDFFRAHAATSDPYLFDHAWNRVREYGGAPAGGMGVGLHEARIWHRRAYGANEVNFMNPEEIGHAAAYEAYRTWIHNSSIYEPLSGDIERQREALTGLAVAEATRLIGFSNRHMDQYTRLTATEAAAHTASYIFYQTRDEEYKSRSRSSYRRGAIDDPYAFDDELLYPRSRSMSRHRSRSRHRSYSMSGTAPYPGSSYSPTMGSAIPQAAYPGGYAGSYSGHGSMHGGSVHGGASMPVPLTAGSAYGGGIPMSGSAYGSGMPPISPTQYAAPMGMGVAPSYHSAMGGGMGSAMGSAMGGSMGHSRSRSGSFSYPQQYAHGGIPQTYSQGYMPTSAPYMGTSASMTSAVPQGQMIVVHKPKKHKHRSHRHSRSSDGDYDDRHSSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIK3</accession>
    <name>A0A9P6EIK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIK3"/>
    <dbReference type="OrthoDB" id="3062275at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="960" mass="106160" checksum="7E6D12A0F65DF700" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIL4</accession>
    <name>A0A9P6EIL4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIL4"/>
    <dbReference type="OrthoDB" id="3270987at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="64"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="505" mass="57975" checksum="7904C519DC921328" modified="2023-09-13" version="1">MDNISLLLHLEARNEAPTAEEKRSMEQERLILKNKIKDIDDEIIQLQLRRVAHERQHQRYIAVLSPLRHFPNEILGEIFTQSSLFDNRYRIVLNISHVCRSWREAVLDIPTLWTDIVIASRPQQFSPPGAVDSATTLAQLDHHIKYAHVKPMSLTIEETPKSLLTPVLRRTFRVTDDHLSVLPQWEHISIFTSRVDDLRLILDYYKLPGTDPTTLTSFAMTSPTVDVSPDDGEALISLLDFAPFTALCNLTCAVRDPFFLDRVMVEWDILTSLTLYAEMTSENYLEQLSHCPALTSLRILVEDGDAGLINGDSITLKNLCKLHVSSTSHPITLIERLSCPNLDSLTLDFTSNNAMEDAFAHFLEKMTDQRLRYLHCCGQLFFRHIEYESPSFPTLAILKLDKHHVNWNDLNIFDYLTPSNNRDNYPSLERLEIIDYPSLSSFEIDSCADMIRSRLEAGTNQDGRNPPSQVLRSVIIKARDNKNKQEEPLMSLHRFYEQGILEGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIP8</accession>
    <name>A0A9P6EIP8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_179899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIP8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="16761" checksum="2C7A7372FB981FD1" modified="2023-09-13" version="1">MPLSIETLLQNGSTLHHAHTQHNRHNSTDSDDTHTLSTLPNFHPTLVEPFFDNDDTSTCSPTHTPPASPNRTLHRKHSSPHLRDDFKRDADATACAASVNGHGHGHHQTQALDLGNHTVGSGKRLDHGGLPSGSTRSRRSLERRHGHAGRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJL1</accession>
    <name>A0A9P6EJL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_809825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJL1"/>
    <dbReference type="OrthoDB" id="3062801at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="35223" checksum="67DF952CFD042D65" modified="2023-09-13" version="1">MLNTPLPFPDEWTPGSVPPALIRFKHSWEAFIDSLVREWKTLNVVSALLASAILTMFQIPQAADDPITRTGALMSLMCGLLSLVYGCMYIVRFGQMRSMFHASRWAEQAGKTKTLIWWNVWVLLAMPAIWLAWAMLWFMGAILSFVWRTGSVNDPDDRAPLGEVPALITRILITSVLALGMVYLVLIIRTLKKYGSHQGSARSLLPSVVNRDTNANEGGNAGQMNSGREASPRKKGAWSAEMADMQKRGRAMDRHISEPYPSRGRQEKIKPNRRSSGLKGLFGSNSPAKNESKAIQVEMDVKLKHDVDVVVNDLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJY0</accession>
    <name>A0A9P6EJY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_851239</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="12">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NAC-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJY0"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000003">
        <property type="entry name" value="Nascent polypeptide-associated complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="14">
        <location>
            <begin position="37"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9530248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="17640" checksum="DD50AB70DADF7B4F" modified="2023-09-13" version="1">MDPVKLAKLQAAAAANRIGGKGTVRRKIVRKTKPSGAGDDKKLSAALKKLNVQPIQGVEEVNMFRDDGNVLHFSAPKVHAAVSANTFAIYGVGQVKELTELVPGILNQLGPDSLASLRKLAESYQAIQQGQQRPAATGAEEEDDDDVPDLVENFDVEAEAKAPGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKA2</accession>
    <name>A0A9P6EKA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Dicarboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_98872</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKA2"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="33"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="122"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="222"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="319" mass="34445" checksum="3D7FE932C8A0C789" modified="2023-09-13" version="1">MSSPSSSKSPLAQAVSDPIPPVSPALSTKPPLKKQPYPFWLGGVAATIAASITHPLDLTKVRLQASGDKRMVQSIKKTLNTAGVRGLFDGISGTWLRQMSYSMCRFWAYDESKKLLGAGKDAPAWKLAAAGSMAGGIAGLIGNPGEIVMVRLQGDFAKAPEKRFNYKHCFDALFRMVREEGLSSLARGVGPNVFRAILMNASQLASYDFFKSELLKTKYFDDNIACHFTASFAAGTVATTVCSPADVLKSRIMNASGPGSSSTMGVIRSSMKAEGPMFMFKGWVPAWTRLQPTTILIFLTLEQLKNAVDWSRAKGFTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKK1</accession>
    <name>A0A9P6EKK1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Caspase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_881530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKK1"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="679" mass="76210" checksum="1CC3556BC8AA50F0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKP2</accession>
    <name>A0A9P6EKP2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_881781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKP2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="15959" checksum="968A92834BCE854E" modified="2023-09-13" version="1">MTQTDEFKVYWLSMRAGVRDSEGIYHSVDDKVNCRESEVDNSCPLGERLTDGENKARFSVKNLAVILEITRGQLEQLRNNSWSELRWLNFLSEIAGSYSMDLRKTWREASKQIRVEEERKDAWRIVKKRSENSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKX7</accession>
    <name>A0A9P6EKX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UbiE/COQ5 methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKX7"/>
    <dbReference type="OrthoDB" id="10017101at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="40"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="31164" checksum="D256B10F520E8ABA" modified="2023-09-13" version="1">MPTYLHGHHASVLRSHSWRTVKNSCAYMLPYFETMLQGNPKLRVLDVGCGPGTITCDFASLYPTIRIIGIDASQNIVDQASILSRSKKLSNVEFAHGDIFHLGYPDSTFDIVHVHQVIQHIPDPLNGLRELRRVLKPGGFLAVREVDHPATRWYPPSPELESWLDRYNQVQLWTGGTPDMGRQIHALLRKAGFSKDKMTKSLGTWCFASKEDREWWAGLWAERVEKSRFAENAIASGVCTEHELRRYAEAWRTFGRDEDGWNAYIHGEVVAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL09</accession>
    <name>A0A9P6EL09_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL09"/>
    <dbReference type="OrthoDB" id="3248709at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="26198" checksum="5B4BD0EEBD926DEA" modified="2023-09-13" version="1">MPISGLSSTIGTVADRLKPHKAEAVQRVRTNALGLVTTLLLSFLLPLPSVPTALRALLSSNQHQRWTADWIWQWVCMLETALVVLLAYNVLEASYAIQYPRAPPPAVVSPLKPKATVAATPKKSFKILSPNTSPQVQKPFAFSPQASASRSFASASMALSSTPGANRSTTYAQSPIDTPSRVLNYTPILNSSTNTQASSTSDYLQTPSPVISAYRGKHSGADVGRALDGSYLSRLMPEVESDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL50</accession>
    <name>A0A9P6EL50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_850586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL50"/>
    <dbReference type="OrthoDB" id="2947347at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="32454" checksum="AA313F280B9C6C67" modified="2023-09-13" version="1">MLDELLPRAFDQYLDQDQPRARLSCYSLPYGALGFISHILTYYTIICLLYGRKPLWPFKSIHNTRLDLILGGIGLVVCVVMSAATMVRCRNAWQPLVIAIWKMSMSLLNGCTALHVAILVVRRENQKKRMEEEEKKNNGDEKTVVDVESESTKEVERPVNAKQAAWWIILYIPGMVSGMAGLMSLVTKAAKYNPDILRLTIAFYFVVGSTLIVGVISMFIIWYRGGGSPFKVGLTGLGVTLTMFIVLSALYSDWCIGMMMGNILGTPSGDKSSFYWSYWAAKRLTMFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELU1</accession>
    <name>A0A9P6ELU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELU1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20213" checksum="A6B5FF2201B87A7F" modified="2023-09-13" version="1">MDTVLGKIKRSTWPKALPVTQNILRVPTLVTVIQLDAFPNNSSGLPWPLMKTNASRFWYTASDMSNTASPKERIEKVTISHLISLDRRSRPVNVNKACRQNPKVTKRSPKLTAWTNIPTSWAALTENKQGILEGQSGTAEVLGRVLEASPELVAQDTYRRLKPVKHSDDGRNNLLDAADQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM61</accession>
    <name>A0A9P6EM61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_124114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM61"/>
    <dbReference type="OrthoDB" id="2635672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="506" mass="57683" checksum="26021F26EED12187" modified="2023-09-13" version="1">MFLKRHQINDPMNMLKYFRAIQYPPLLLPLIQAALWIKDIQHVDCGMNAGYDRIWNDVGDLKYLVGKQWPIQTMKLHLRFLDGWASASQRNGNPRALDGVKWVKCVTELLDAVLAQGCLTLEVDGGHSLNRLYVEKETSGMTETADVQSFPTRGQVVRKRLTAFLKQTSAWIFCQPNKTLPDLRPSAAPSGPYLNDVTFSHSMMFQDCFYPWTLQMFAKNSATITHLSFQVTSLPAETFSHFLFSITLPRLGHLKITAHSNQNHLTITRTVKFSEFLAFFERHSSIETLDLQGVERPEAPPILETCLLPQLKQIVAHPVWISTLITPSKSCPDAFPFIESIGITTEYPTFMDPFEEEHVYELINDALWAITRASFPRTITLELQLKTKRGMLDWLDKHSSLGKENSIISSLWCVSTLVLTTRFYVCFGREEIHHLPSWLALFPALKIVNIPDLRQEKDGYRLFDDSPLLRKISVKCPTLEKVESALASIDLSTLLDPAERPHLNVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMH7</accession>
    <name>A0A9P6EMH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HMG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_761155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMH7"/>
    <dbReference type="OrthoDB" id="5598737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040648">
        <property type="entry name" value="HMGXB3_CxC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34305:SF1">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18717">
        <property type="entry name" value="CxC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG" evidence="1">
        <location>
            <begin position="252"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="832" mass="93647" checksum="0996E94EDF931ADE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN79</accession>
    <name>A0A9P6EN79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_847337</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN79"/>
    <dbReference type="OrthoDB" id="10266980at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="57"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="31680" checksum="F3E32A534C7461D1" modified="2023-09-13" version="1">MVLLERFVSEKLGLTKFPPFLPTFYAAFLGFTLIHLGLAPYFSARWFPVAFGAKGRGAKNNWSIHVVSQVHALIIVPYAAWCILHEASESSLQDRVFGWDSRAGHLFAIACGYFVWDTLDASINFIDAGFVAHGVACTLIYSMVFTPFVAYYGARCLLWETSTIFLNNHWFLDKLGRTGTRIQAINGICLLGAFFFVRLVYGGMISFHFMMDVLEMRRQAPLLHVMVYGIGNVVLVGLNWFWFFKMISALRKRFDGPGERTKLLNQAETASPGVPTTTTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP79</accession>
    <name>A0A9P6EP79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">RNA helicase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_585051</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP79"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="13">
        <location>
            <begin position="90"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="11">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="11">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="11">
        <location>
            <begin position="158"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9532845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="645" mass="71648" checksum="DF85D52976DC38B2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP95</accession>
    <name>A0A9P6EP95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_806489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP95"/>
    <dbReference type="OrthoDB" id="4991875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040429698" evidence="2">
        <location>
            <begin position="30"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="222" mass="22790" checksum="BEE596913860550D" modified="2023-09-13" version="1">MIFSRQNGIYVFLWLNAFLMISQFSPVYGQSTTGLFIPGFDPQPVSADIIGIGSDGHTTWAIHQGQRTPGDTSSYEDFGTATLVQGPSDAYLTYVNSAAKVTLAESCTVSDSTLAICAVFGQGLSGTQTEVYTPIPVQIGLTLTGSVTILPVTTTAPGSTSASTSGSISGRSTGSSIPASTSVSSTSQQTATLPSATNQATNNAISKVLGSSIIFVVVVSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPP7</accession>
    <name>A0A9P6EPP7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_847253</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPP7"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="198" mass="22518" checksum="59B891522B4B6BCE" modified="2023-09-13" version="1">MTTFNDVQSKAQEEIDRVVGKERFPTLNDRPSLPYVEALVRETMRWMPVLPLAIPHYTVEDDIYKGYFIPKGTMVLGNTWAISHNTTIYDESDRFDPSRFFNLDGQLNDDDLSYAFGYGRRQCPGRHLASATIWLNMAVILAAFNIRKQKDSLGKDIPLTSGFSVSSIAVRPNPFECLITPRSDAAKALVLERIVYQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA4</accession>
    <name>A0A9P6ERA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Senescence domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_783294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA4"/>
    <dbReference type="OrthoDB" id="20821at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009686">
        <property type="entry name" value="Senescence/spartin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06911">
        <property type="entry name" value="Senescence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Senescence" evidence="2">
        <location>
            <begin position="228"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="524" mass="56065" checksum="57C77456A32C65C7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERV2</accession>
    <name>A0A9P6ERV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_879810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERV2"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="60588" checksum="88F12310111FF065" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES03</accession>
    <name>A0A9P6ES03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_804240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES03"/>
    <dbReference type="OrthoDB" id="9971669at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF67">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04010)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="19"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="503" mass="55714" checksum="0FD3A271F5E5CFAA" modified="2023-09-13" version="1">MDSHVKMTRSILWKLDTHVLPPLAVLWLANFIDRSNIGNARIDGLERDTKLVGDQYNIILAVFYVTYIAVEMPSNMLLKKMKPNRWIPFLVMMWGIVTTLTSLVQDYKGVLAIRIFLGFTEGGILPGMVLYLSTLYKRHELQLRVGIFYASASLSGAFGGLLATAISKMTGIAGLDGWRWIFILEGIATVIAGGISIFILPESLENAHFLTEEERIFAVRRFHMDDKTLGSTGNPEAPTPNSEKKSTAEVRLELIDLTRSLQGAPEEKFEWYEVVRGFKDIQTWLTGFAYFGLLVSLYSYSLFLPTIVSGLGYSGSQAQLHTVPPYIPAAFLTVLVAFLSDKLRWRGPFVLICLPIAIVGYILAIVAKTNNIRYLAVFLMAAGVYPAGPCILSILPNNSAGHYKKATTTGLQLAIANSGGFLATFAYTPDQAPRYVKGHAISLAFVSLSWILIACNVAYCSWENKQRALGRRQDNITKHSALVESGKSNAPIGDRHPDFRFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESG6</accession>
    <name>A0A9P6ESG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_901053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESG6"/>
    <dbReference type="OrthoDB" id="2987506at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="24874" checksum="520702522DA052E5" modified="2023-09-13" version="1">MTTFTVTVNIQPKALASLKGYRVCLAKPVGQSGGPPAYNVVALASIVTANNVIKFTDTFSIYGTLQTFNAGSATAQGNAPTLPITYGEAYHLPDWTDPPSVGNSTVAPAAGFAFINGVQASVVVALQNGPTVGGNSAGANSPFYISPSPDIPGTDTLTPVTEVALWFQRDIVTTTMIDLDMSTVHVMNLTGQTTVATTYTDSFQWQDDPSKVVDYTKVAPAAVKPIKKVEEKKYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESJ8</accession>
    <name>A0A9P6ESJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">assimilatory sulfite reductase (NADPH)</fullName>
            <ecNumber evidence="4">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_843784</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="4"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESJ8"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06207">
        <property type="entry name" value="CyPoR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000010">
        <property type="entry name" value="Sulfite reductase [NADPH] flavoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF109">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="671"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9534160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1056" mass="115320" checksum="5A78AB5CF2CB3BC4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETE3</accession>
    <name>A0A9P6ETE3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7719 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_843016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETE3"/>
    <dbReference type="OrthoDB" id="5597489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056136">
        <property type="entry name" value="DUF7719"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846:SF1">
        <property type="entry name" value="DEACETYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846">
        <property type="entry name" value="YALI0B21296P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24841">
        <property type="entry name" value="DUF7719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7719" evidence="3">
        <location>
            <begin position="137"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="23291" checksum="F95808C1C457A65B" modified="2023-09-13" version="1">MPRQRKGKAASQTVPEVSSQAPRNDAPSKPLIEISEEEQWRIIKQTGILEVAEERDASGAQEIIEAESLSLGDEIFNAALLIIPFSFLLLLMEILIHHQYGKRVSLDMMMDRMGPGVPILSLFIFYTVRYKHHRRTQFFLFLLSCAAGSRLMYQYNRANWLVKIKQCPPLITIWVYTVLQLDLGPCVLGLLTVAGFSWLKGLTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETS2</accession>
    <name>A0A9P6ETS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine carboxypeptidase S28-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_232208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETS2"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040150468" evidence="7">
        <location>
            <begin position="23"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9535131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="571" mass="62915" checksum="90B7E4811EC034ED" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETZ5</accession>
    <name>A0A9P6ETZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="7">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_216908</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="7"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETZ5"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002055">
        <property type="term" value="F:adenine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000004">
        <property type="entry name" value="Adenine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002636">
        <property type="entry name" value="PRK02304.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF3">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="12">
        <location>
            <begin position="48"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="19962" checksum="21AAD8B797C1EDD4" modified="2023-09-13" version="1">MADVELIKKQITYHPDFPKKGVVFLDIFPVLRNPAAFEALLNHLENHIKSHTLALSESKKIDVVVALDARGFLIGPILALRLGAAFVPVRKGGKLPGECVKVTYEKEYGADIFEMQSDAIKPGQNVVVFDDLLATGGSAKAAGELISQVDGKTLEYIFMVELPFLKGSSKLNAPVYSVIQHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV18</accession>
    <name>A0A9P6EV18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV18"/>
    <dbReference type="OrthoDB" id="3228420at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="125" mass="14279" checksum="77C421E98F855C00" modified="2023-09-13" version="1">MLESGVQHQPAMKVGGRRLSVTNRHKPHNACERLSPETEDKMQETGPADYPRPAPHTEHVPHAHVQHQFEEETPFRKDKKHDAEWKLKENGHRKTEPTRPTREAAASQRNQALRISQPAGKALHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVK3</accession>
    <name>A0A9P6EVK3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dicarboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_842253</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVK3"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="93"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="199"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="31275" checksum="FB449A051AB370B0" modified="2023-09-13" version="1">MPTEIPFWLGGVGASMAAACTHPLDVTKVRMQTLPDGRRPSTFRVMQLSITKHGVGSLYAGLSASLMRQMSYSLVRLGAYEKMKTQLSKDGKPSQTKLLLAACLAGGMGGVAGNPADILLVRMTSDVVRAPENRYNYSNAISGLVSLVKSEGVQGLARGLGTNTFRAVLMNASQVGSYDYFKSVLLSGPLPIIDRQLEDKLPVHLMSSCAAGMFATTVCSPADVLRSRLMAGSCNTTFAQVLRTSLQQEGVRFLFKGWTPAFIRLGPNTVLMFVFYEQLKKMWRERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVL3</accession>
    <name>A0A9P6EVL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_912930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVL3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="25890" checksum="77B177B3C82A8532" modified="2023-09-13" version="1">MPLLCDVKNELGSSGELTFELFGCYVEGMRWIQAQTEGPYIQIFGAVTIDKPVIELLSGHIPLYYHHCDMTSRRDLASLLWSFKETFMTLRAFHRDVQNREIDADQSGPYSTYLSTIVEDETDLNGTEVIVKFSPEKYGLEAHKEAAKLGFAPTLLGRTLLPGQWNMVIMAKLDDDFKCFDDLDDLDDQERQAIMSNIRDSVNKLHASNFVHGDLRKANVEVRKQPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI42</accession>
    <name>A0A9P6JI42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate-binding module family 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_911670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157990">
        <property type="protein sequence ID" value="KAF9521780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI42"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057230">
        <property type="entry name" value="DUF7908"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25485">
        <property type="entry name" value="DUF7908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040155624" evidence="2">
        <location>
            <begin position="21"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="3">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9521780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="200" mass="20872" checksum="DEAA3C6900324B4F" modified="2023-09-13" version="1">MVRSIYLSTIALSAVGSVYAQSTAPQYGQCGGQGWSGATTCPSGWTCTASGQWYSQCLPGGSGTTAPPATNPGSPTSTAIGALPTLQTGWNFIRAVVDPNFHKYLQSEVTGTPSDAVLADRTTAAQFQITNGQLIQSVSGGNLYATVEPKTASATKLKVSWSKTPDTLGTFVFSGDTVTWSSTTVTRPQNNFYYTAPGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI44</accession>
    <name>A0A9P6JI44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_921322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157981">
        <property type="protein sequence ID" value="KAF9521853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI44"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="632" mass="71464" checksum="91912C2DDB7FC550" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJN5</accession>
    <name>A0A9P6JJN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJN5"/>
    <dbReference type="OrthoDB" id="2131701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23422">
        <property type="entry name" value="beta-trefoil_Ricin_MPL_CNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="142" mass="15383" checksum="E2D1A72183A6C9D3" modified="2023-09-13" version="1">MPKPISGRSYKIGNCASKTWIDLNDSDKKSIIGYQAGGGANQLWTLIETSEGPWALRNCRDTNKYLGFGGKAASGTRLIAEDYGIQLFNLQSVGNSKYYSISVPGHDNLVIDMSASSSLNGNPILIYSKHGGPNQQWELVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJS7</accession>
    <name>A0A9P6JJS7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_951188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3239511at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1286" mass="143565" checksum="F1C8FBBAC5AAF8CB" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJU3</accession>
    <name>A0A9P6JJU3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_775664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJU3"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="111" mass="13130" checksum="3359D44DE25980FB" modified="2023-09-13" version="1" fragment="single">MDYFILPLRHQNSRLWISGVPISICRQFDWFDDIVNLHEQIYEALCSARDTMTPATDRVSEALRWWVMKAEVYQPYLVKLGHAKDEILRTREDREPDGAGADFGEFIRLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJY4</accession>
    <name>A0A9P6JJY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptide hydrolase</fullName>
            <ecNumber evidence="15">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_821098</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJY4"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053976">
        <property type="entry name" value="PFF1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22251">
        <property type="entry name" value="PFF1_TM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="522"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="646"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="710"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="125"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease transmembrane" evidence="20">
        <location>
            <begin position="456"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease transmembrane" evidence="20">
        <location>
            <begin position="608"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="19">
        <location>
            <begin position="740"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9523727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="998" mass="109504" checksum="7B4A131D744BD9F5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKM0</accession>
    <name>A0A9P6JKM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_640939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKM0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="88" mass="10016" checksum="F531BF4688DF37AB" modified="2023-09-13" version="1">MRLPGKIQPIPWIKLLISYICVCCVLLIVPSLQSLSSPPSSYASRFAENSKVADPTWIQLNKLLRLNKCSVSYFGLFQVYARNFDHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL26</accession>
    <name>A0A9P6JL26_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_909639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL26"/>
    <dbReference type="OrthoDB" id="4179406at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="459" mass="51170" checksum="3A0E4C97EFD82DC1" modified="2023-09-13" version="1">MTQQQSRVPGSQSRTSSDGQQQKFENEKEDGERRGGDSDWEDEGDPFWPGHLRTGSPVGTTGAYTRPSPYKRRRPTFQVNASKTQTSRLSSTPTPSKPVRAKEKQDDQPLISQQTLRIAFSVVFMLVLLSLLSTWTRLAIQTALAPICILPGFFRFPVYTWGTVPPIRRSQWADYPRLIEAETKAFDQLMDGFVGGGALLLEVKHAEMATEELLSLIQISDLKAKDVLASLLYEFVYDAKRTCRGLQKISAKVGGAADNIIVVNDHALKSIEAARSNEPSRLMRALTPGPPKDKPIDEIVAETFKVATNTFSRNLESLIVEAKVSLENLRGLGERLDSLHKLLSRENASNPSSKEYIFGDLWAKIGRNNKKLRKFDSHLALLKDLEKYRKKTRSHVFAALKMLRGVSDSVEDMGVRIVAPNLLGPTVPVEAQMKSIVTGLQRLREGRTRANKPEDQSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLV4</accession>
    <name>A0A9P6JLV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_771916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLV4"/>
    <dbReference type="OrthoDB" id="3365399at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="53299" checksum="A9D3DFA82964B9E5" modified="2023-09-13" version="1">MPPRPRPRPIPKATTSTSNVVAGSSSQAGSSNATSASPTEQAVSKFRDIVVNDTDEMFMKNRNRSSKTWQKLEKINKGIAVVLTCCFGGQDEKDLTPRRRKRQKKDASVVPSWQKNSDFKRMLSVDLSDSSDDDIQIIGDSSTPRGNHKGKRKRPRSRSRSITPPPALPEHQLQNAKNVVRQALRGAVRPLSPTLDLDESSDNIELGPEFTMLAERIRKEGRNRGSSQAPEGVEGDEVLITVKWVPHPLNPNGESEEWQYKVNRTDNFRDLFDAVADDAGVNAINLILTYQGKRFFSSITCQTLSIWSDSALFSAYEKTAFEHIQKNQRISYSQPPAGLSQTRAVVQSNTDGPIELDSDDDDAGYQKNHASPPIETQTQTQESDADSEAEQGDKIRIILRSAVTGNKDFTLIVKPTNKCGSIIKTFIKKAGLAAEYPHLFGGKGGGKTKKDPRLCIDGEKCDNDTEIAEMDLEEGDKVDVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN08</accession>
    <name>A0A9P6JN08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">STE3-like pheromone receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_770665</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN08"/>
    <dbReference type="OrthoDB" id="2874149at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004934">
        <property type="term" value="F:mating-type alpha-factor pheromone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14966">
        <property type="entry name" value="7tmD_STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000481">
        <property type="entry name" value="GPCR_Pheromne_B_alpha_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001499">
        <property type="entry name" value="GPCR_STE3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28097:SF1">
        <property type="entry name" value="PHEROMONE A FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02076">
        <property type="entry name" value="STE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00899">
        <property type="entry name" value="GPCRSTE3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00901">
        <property type="entry name" value="PHEROMONEBAR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="8 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="340" mass="38761" checksum="C3EBCDEAB2AC663B" modified="2023-09-13" version="1">MLASQDPTYPLFPIFAFLGFILSLIPLPWHIQAWNSGTCVFMIWTAVSCLIGFINSIVWRGNLNDPAPVWCDITSKVMIGITVAFPAATLCISRRLYYITSGNQASFTMDDKRRMVIIDLCISIGIPFVVMALHYIVQGHRYNILEDIGCFPVVYNILPAYFLVFMWPIILGLISFVYSALTLRSFWIRRLQFAQLLSSNPSMSVSRYLRLVMLALIDMMCTVPIEILCIYLGNKGVRLAPWISWEDTHFNFSHVIFVPTLVWRSDPSFRTSVELTRWLPVLCAFVFFGLFGFASEARRFYGIAFSKLSKLANLHETSTSKDCKMKGLACVHKLYISNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNM3</accession>
    <name>A0A9P6JNM3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNM3"/>
    <dbReference type="OrthoDB" id="3070163at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="369" mass="40518" checksum="DD7E0022FA31BD6F" modified="2023-09-13" version="1">MDDVPLVGGLGNEDVESTRPAYARAVGSAPTAAEVQYPDELLVNAEDGESQPLAMGIKTRKPRTTKNQKAKDVPEQNSLVAFTYDKRWLSRFPPTLMHQLYISSEPFRHFKVDSPDFLVIFQQTFDLAFPNIDHTFVKGDSHLGKAQDHIKAKRSILASDIFKSVLKFFKQDKFGKDAIAEYALHALRNDGPAWYSKPTPLTQTGKIHLKYVKPDGLYESLFTLPFAIKFLRLCNASLWTPEISPTAPPIGLYSLITLAVEHAFHAFSAAATAHVQSATSGLGSLTQDQVLNLDAIAPPAFSQAKYCRELGTIRNSKVLKISQNRWSAILSSTNKAIAKSAPQALEPADEEILSAYCHGACVTSSPSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP18</accession>
    <name>A0A9P6JP18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP18"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="128" mass="14075" checksum="76560DBE0605C69B" modified="2023-09-13" version="1">MTHSSTAFFQGANSVQLEGTTINSTTVGGNIINNHLSGAYGSEFQQLIHHCLLGALVDSNKQYDAPQCEEETRETVIQQMDDWGRSRARQSSPVMRMRGGVGAGKSTLAQTIAMTYKRESRQRSNYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPC2</accession>
    <name>A0A9P6JPC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_791687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1315"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="834"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="886"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1076"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1132"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1205"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1434"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1562"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="245"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="400"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="840"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="886"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="901"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="915"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1143"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1172"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1207"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1260"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1434"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1456"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1562"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1578"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1597"/>
            <end position="1610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1663" mass="182649" checksum="C783B8C0DA30F212" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPU1</accession>
    <name>A0A9P6JPU1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPU1"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="130"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="413" mass="46522" checksum="E23CD75C7DF181C2" modified="2023-09-13" version="1">MLCRKLSALSSRHKIYPAHNPAFIRRISGPPEAKPAQGGIFENFRRWRIALFSRFEARNPSNNLKKKPPEQDTFHFIIHRLSDLARIAQALELPSNVHVEFLDTPQAVESAISPILVPQDAEIEDSSNILVSMDTERNIMRAIGVSVIQLAFHSTPERIFVVPVHKFDSLPASLLETFTSKRVIKIGNQVNSDLSTLQRQFKELQQTKSFATVDLQAFCLERGVIRPGDSAALQALLVKALGRYMNKKPHDYHNWEGRTLSKIMLNGGALDAYAIRLIYEKAATQPIVPLVHYDTQPGTAVNLLGRIGWFNELVARGRISPLQPEKHDSVEVKTPDRSRLLVDITELVYPDQGAMFYPLPGEHHTHPERRRKPAVYTLGQLHSRAGNTPLKVVWPISSLELSKVPERAAEQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ01</accession>
    <name>A0A9P6JQ01_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HMG-box</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_853133</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Weakly associates with the stable SPT16-POB3 heterodimer to form the FACT complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NHP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ01"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01390">
        <property type="entry name" value="HMG-box_NHP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="34"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="34"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00064996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="116" mass="13109" checksum="F269701891598D3D" modified="2023-09-13" version="1">MPKEASGKTKRKAAEKAEKSTRPAKGNKKDPNAPKRALSAYMFFSQDWRERIKTENPDAGFGEVGKLLGAKWKEMGDEDKKPYVEQAAKDKERAEEEKAAYDNKQKASTPEEDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQU6</accession>
    <name>A0A9P6JQU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQU6"/>
    <dbReference type="OrthoDB" id="3267422at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040294484" evidence="2">
        <location>
            <begin position="33"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="281" mass="29919" checksum="8B75A567707EBEB0" modified="2023-09-13" version="1">MQSVLRSSWHYSAWSSLICCFVVLLSLRIASAQEGSTQDVEIPLTSPSLVYTPFICNTTAVSINPSGCAVAWQISADNESASAIGPSTEVRNIIPQMFFQFQASKLHMAASSASNATINITLSSNGISLTSTFNSSMGSASIINLPQNRITLLTLSLNPSPVSTIFELTSISITIPSDANTTSLLPAPTIPRSASLPSVSTSFSAVVGATSVPPKSHASKTMIGQAVGLTVGLGLGLTLITIAIFLWWRRRRRKEDELLDKVSVAEARSEWRGSPTNFALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRJ5</accession>
    <name>A0A9P6JRJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRJ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="160" mass="17332" checksum="D9717E4267D12F12" modified="2023-09-13" version="1" fragment="single">MTTQVIEETVASNPCRPIIEPSTRTDIQPTSIPLPEIVNAVLGAKEAPSKGFIVVLDSEKDIVGKPVRFGHWTDKEIETEENEDTSNDGSDGATDDNSTVDGEAKEPCKGDKSEGPLLEDITGGDENKSPLWLGLKVYMQFEDTLGRNSVTIGSVVREED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRY2</accession>
    <name>A0A9P6JRY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_100126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRY2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12079" checksum="0F41E19F5C5F2D5F" modified="2023-09-13" version="1">MTSMRPGLIAVPVFHSWPPGRCCNVCLSILAGDRCLRLSLPGQRRFGSFQNIFPIVVILGVISDFTQRPSFELTNHPKSPFCWSFRPFGTHLKVPLGIFLVVPKSNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSM4</accession>
    <name>A0A9P6JSM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSM4"/>
    <dbReference type="OrthoDB" id="3251070at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="42059" checksum="47257FDC43AAFFD1" modified="2023-09-13" version="1">MPAKRRKIVSMQEVTQPRAATLEDGSKNSSHEDASNENRGLLCLPYELWGEIFSSLNGIDTFTQAPRHWSYLDYPVLPVLYLEKTDVLRILCQVSVAYRRNFLPFLWYSLSACCAARPGPDVKPMMFFRHVAETLVSKCEGLSRNPELAALVRCVQLALTRYQSASVIPTLASTLARLPNAHTLHILHAHTQMTTALKDGFQGISLPQIRTVIVPGYCHEILRCCPGTKTVWCTEEDGSKLVTVIGSHCKEVVELRGVLFDDTKAKRIVKAVPNLEVIEIMPYEAEVFLTHLTAFKNFRCLILKDVRSFNQDEDKGKIQLHHWEHTLRSCAAALKKLPPFKDGRKRSLRIAHTRSIAGKGGPRPVEYTEVDLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT38</accession>
    <name>A0A9P6JT38_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Tubulin gamma chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_849022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Spindle pole body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT38"/>
    <dbReference type="OrthoDB" id="10249382at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000004">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000049">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="10">
        <location>
            <begin position="48"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="11">
        <location>
            <begin position="248"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="50530" checksum="E2751546EAB003FC" modified="2023-09-13" version="1">MPREIVSLQFGQCGNQVGSTFWQRLCLEHGISKDGILEDANIETYDRKSTFFYQADDEHYIPRAILVDLEPRVINNILASPQGRLYNPENIFKWKDGGGAGNNWAQGYFSGEQVYEEIMEMIDRETEGSDSLEAFMLMHSIAGGTGSGLGSFLLERLNDRFPKKLLQTYSVFPNTQEGDVVVQPYNAILTLKRLVKNADAVFVLDNAALSRIAADSLHVQTPSFDQTNQLASTVAAASTQTIRFPGAMFTDLVSMVASLVVTPRCHFLTTSYTPFTSDQVDEAKVVRRTTLLDVMRRLLQPRNRMISAPVSKSSVYISNINIIQADVDPKEVQQCLLRIRERELATFIPWGPSTIQIALAKRSPYIKSSHRVSGVMVANHTSIAPFIKKMLDQFDRLRKRNAFMEQYKKFDNIMEEFDDARTTADELQKEYRACETPEYANYGGPKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT48</accession>
    <name>A0A9P6JT48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_848107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16039">
        <property type="entry name" value="PHD_SPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="1056"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="281"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="570"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="627"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="722"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1305"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1389"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="454"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="635"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="660"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="776"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="818"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="831"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="842"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="886"/>
            <end position="903"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="913"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="925"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="949"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="963"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="999"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1032"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1308"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1325"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1398"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1447"/>
            <end position="1456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1456" mass="158582" checksum="384840019F410450" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT51</accession>
    <name>A0A9P6JT51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_890895</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT51"/>
    <dbReference type="OrthoDB" id="941679at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040271496" description="glucan endo-1,3-beta-D-glucosidase" evidence="15">
        <location>
            <begin position="20"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9532712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="31210" checksum="75363882084542B0" modified="2023-09-13" version="1">MIFQELVFFALVMLAAANAASNHFAGLTIANSVGGTVSYNCRTQAQWNQAVNIAKSQGFGAIRILGFDCNALNFASSAAAGVGIKVLAGIYVDGTMANAANGINNDVQAFRTAYASYGAGRYLGLTIGNEVNDSPSNVMAKIYELRGYLRSVGVTTPVSTVHTWVNIKDHPSLCDADFVGANAHAFYDGGRSSGQAGDFVFRTVVPTLKAACPGKKVYITESGWPSRGGRNGKAVPSITDEGQALLNLNCAARDDTSVSVFAFEYDDQLWKRNDNERSFGIVGKISLSDVFNPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTH5</accession>
    <name>A0A9P6JTH5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine diphosphorylase</fullName>
            <ecNumber evidence="3">2.7.7.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_785689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="3"/>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTH5"/>
    <dbReference type="OrthoDB" id="532420at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04193">
        <property type="entry name" value="UDPGlcNAc_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000075">
        <property type="entry name" value="Probable UDP-N-acetylglucosamine pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF2">
        <property type="entry name" value="LD24639P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="53905" checksum="E964367C98216AB9" modified="2023-09-13" version="1">MTIDILTKRYESADQNHLLTFWSKLTAAQQEELKAQLDALDIERVNRIYAKAVSAETDAAKPAAESEAITPLPQGASQSLTDKAKEKEWEQIGLEAISRGEVGVLLMAGGQGTRLGSTAPKGCYDIGLPSHKSLFQYQAERIARLQTVAETRFSKPAGNVIVPWYVMTSGPTRRETEEFFGKNSYFGLDSKNVIFFEQGTLPCLTMEGKVLLDKPSKIAVAPDGNGGLYAATRSPLFPGSSDSVLSDLKKRKILYVHAYCVDNCLVRVADPVFLGYSVQKQADCAAKVVPKASPTESVGVVACRGDKFSVVEYSEISKEQAERRESSGELSFRAGNIANHFYTTTFLNKVESFEDELAFHIARKKIPHVDLETGESIKPSKPNGMKLELFVFDVFPFTERFAVLEVERREEFSPLKNAPGTGSDDPETSRRDLLAQHKRFLEAAGAQLKDGVEIEISPLVSYAGEGLETVKGKVFTKSGIVEGIEQLDALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUY9</accession>
    <name>A0A9P6JUY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_542476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUY9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="205" mass="22823" checksum="750344121B8717C2" modified="2023-09-13" version="1">MTAEGNYENADAHFLNAVKNEVLAKQNYNDAQPDFLVLREADVETFVGKVWLEKKAERESAELKKNSRKGELDHERGLLITLKDQSTREVTNIAKLEADIKKAKTAIDDGASKTTNYQNHHKTLTALHNSLQDCREHLIATLRYNVGGGAKFSTVREKLKGLINALEKAEDFKEPLKILDRAALDHLMTRIPTIAGGSTAGKLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUZ6</accession>
    <name>A0A9P6JUZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_873412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUZ6"/>
    <dbReference type="OrthoDB" id="201153at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="5">
        <location>
            <begin position="48"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="5">
        <location>
            <begin position="117"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="411" mass="46155" checksum="7CBFE2498B3335CE" modified="2023-09-13" version="1">MILSDTNIKRLVHKLTKMHGAALKIGQFLSIQDTHILPPSLDSIFRQVQDAAHYMPYSQLEEEEEKNRSPFIQFTPIPFASASIGQVHSALLSPSAYSSNRQERGYSGQHKTRPKTVKVQFLGIKESIKSDLSYVSWLLSGLFLDRTIEVMSSELQDECSYTLEASYLRLFASPSFLGSDPRFRVPWVWDGSTDTVLVMEMFEGERVGGERIASLTIELCLLELFKFHTMQTNPNFSNFLYNIHTRRLGLVDFGATRVYGREFMKIWRALLEAAVYGDEQKCREMSREVGYFVDGESETMINTHLKSLSLLATPFKPSTSTSTLQPFSFAPDSEWGNITAEIRSLIPVMLQERLTPPPREAYSLNRKLSGAFLLASRLNARVDTRAIWEKVLASVDGIDAGASASAIAGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV48</accession>
    <name>A0A9P6JV48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleoporin Nup120/160-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_843354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67716at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059141">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056548">
        <property type="entry name" value="HEAT_Nup120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056536">
        <property type="entry name" value="TPR_NUP160_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11715">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23300">
        <property type="entry name" value="HEAT_Nup120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23347">
        <property type="entry name" value="TPR_Nup160_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup120/160 beta-propeller" evidence="4">
        <location>
            <begin position="61"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin nup120-like HEAT repeat" evidence="5">
        <location>
            <begin position="815"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 C-terminal TPR" evidence="6">
        <location>
            <begin position="1117"/>
            <end position="1355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1361" mass="151568" checksum="0641CBF6EBF6419F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVM1</accession>
    <name>A0A9P6JVM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVM1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7638" checksum="BA5CB2A911408C75" modified="2023-09-13" version="1">MYDLPMVASEIETSTFNGSQLLIALLFTLSPLHEPVLIYLFAPPLYKTRGRSNTADIFVSCTSFRIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW48</accession>
    <name>A0A9P6JW48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_902123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW48"/>
    <dbReference type="OrthoDB" id="2693038at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="32287" checksum="F5DF76E4A5EE785E" modified="2023-09-13" version="1">MDAHRRHNIHRRQKGGGLLDPILGDPTKDTKPTSASSVAPTLKPAASSSAPTPSSSESSTSSAPPSQTSENPEVTTAPPAPVTSFVPGRTQVVTAGGANSTSFLAPSSTNTSPAQTAFLDNKVLSGVVFTFVGIIGFFLIVFAATFFIRRRRNKQLVDEAVAFDPSTIASYEDAEKGRMSSSVGHGSATGNAPEIQKAPIFDQYIPPVPYLPPQGTVPRGQSLYMNPAASLSQSGQAFVAPESWGSPALPQSSQANLVHTNNSRPSSDDGNHRQQQHHTSSRSSSGEIKFAPTVPPDMRRYYDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWK6</accession>
    <name>A0A9P6JWK6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_206747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWK6"/>
    <dbReference type="OrthoDB" id="2602938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18499" checksum="7724538CA2571F22" modified="2023-09-13" version="1">MSAPAGPKQPTLFSIKDQKAVSDQLLPRLPFGFTPRGLHVSEWKIKDWLSTSPTSLKRSSPDFECGGHKWQIHLFPLGLVKARQQEQITPTPKTSIALYIVHSDNCHHSETWKVEADVVVAICNSQTPSIFIKQTYHHQFTPTTPLAGSHDFRRLRDIMLWCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX57</accession>
    <name>A0A9P6JX57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_901243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX57"/>
    <dbReference type="OrthoDB" id="3255301at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="123" mass="12926" checksum="63626D2A9552A48C" modified="2023-09-13" version="1">MTTMTLGLSRPAVPSPLANPAHTVPPAQRMVPKRGPSFPHSRALRPFPTISHLVQPAKGGQPGSKAPIKLIEPPKNFKASLNSADKSESIAYNIPSAGSSPAVLSAIPMITRSVQPAAYRLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBF4</accession>
    <name>A0A9P6BBF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_743152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158097">
        <property type="protein sequence ID" value="KAF9521374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBF4"/>
    <dbReference type="OrthoDB" id="2928561at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="32"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9521374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="9106" checksum="3AF9AC8984C5B259" modified="2023-09-13" version="1" fragment="single">ILISHGASDAFVDSKDRRDPPRCAPETRDGIHQEIIDWVNNPDLPAAIYWLFGSAGAGKSAICQTIAEIFNEKGLLLGNFFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3V6</accession>
    <name>A0A9P6E3V6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3V6"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959:SF119">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19959">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="36"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="467" mass="51966" checksum="E2AA16BB44D53EFF" modified="2023-09-13" version="1" fragment="single">MRMGGICLFHGANNVSISGNSSFNIYWGSMGGGAWITFVDAAGRSYPVPEYLTSSYETFLKAINLMLQQDNEIARGQQRLIKRRMYDLCIDQGNQILPINGQESWSQVERDMKIVMRIPIWQEPGEINSKRTYCCPLLHCQLWNEDPSMGGTSTIDCKGCNSRFQISDLTGRETSEISSPIDISDLSFLRNYHLLSVSSELGHHHLGYMLNNHFNETAELANLDYAVNHYHKSIQLSSENHPSLSLTLRNVGQVLHKRFRHTGNIADLATAIDHAKNAIQLTAEGHPHLPACLSSMGLALLSCFHQTGDLGDLTSAIEHLQKANQLTPEGHPDLHAHLSYMGHALQSRFEQMGDLGDLTSAIEHLQKAIQLTPEGHPDLPACLSYMGLALQSRFEQMGDLEDLTSAIEHDQKAIQLTPEGHPFLPTYLSNMGFALVSRFRLMGDLGDLTSAIEHHQRAIQLTPEGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4B6</accession>
    <name>A0A9P6E4B6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_800905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157957">
        <property type="protein sequence ID" value="KAF9522174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4B6"/>
    <dbReference type="OrthoDB" id="3242409at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="11"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="26077" checksum="B23A95A45E2938AC" modified="2023-09-13" version="1">MSTTRLQYNVQYASLALIYYDYSLTWTREVKYFWRRKFSLSTLLYCLCRYSLVANVLYTLAISKKLTAISCNAGYQICSTLSVFGRVGILVVWGARTYAVFDRHKIILAVFTTLGLLVIILSAMHVPFVTCIPKKGTTRDLGMTHERFVFRNLNQCDLRHPIPTFGRDDHILRSSCCRTHNFATTSPKSVTNNRFNSHNHAARIALYQRCIRALYWNDCSSQYPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4G3</accession>
    <name>A0A9P6E4G3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_117418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157951">
        <property type="protein sequence ID" value="KAF9522315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4G3"/>
    <dbReference type="OrthoDB" id="336321at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051988">
        <property type="entry name" value="HRR_RAD51_Paralog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46457">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46457:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad51-like C-terminal" evidence="3">
        <location>
            <begin position="81"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="32598" checksum="09F4D0DB18F6F046" modified="2023-09-13" version="1">MRLSGLVPSISAELVDHLESLNIRTETDLLFSSTADMVKRLPHSGITASELEATKRIICEQCSSPGLSAFHSLETKLAPQELSTGREPLDRILDGLSGLVQISGDRESGKTLFCLNIVLRQLAFREVTNVLWIDTTGSFSADIARQIVESTRMELSVLERLKISVAFDIETAQGLLEEIYQCYPKLLVIDTITPLFAPLLSATSAQGHAVMSEFMGQLRLYAQAQDATILVVNNTARQGPETTARKPALGPSFGLLTDSTLWLQKIPSDSKLNYSATLIGSSYRSNLPIFNFKLRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4X0</accession>
    <name>A0A9P6E4X0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_864175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4X0"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12565">
        <property type="entry name" value="RRM1_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12316">
        <property type="entry name" value="RRM3_RBM19_RRM2_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="225"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="410"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="537"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="643"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="486"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="734"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="743"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="764" mass="84226" checksum="86C9D2899E623197" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E531</accession>
    <name>A0A9P6E531_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_741876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E531"/>
    <dbReference type="OrthoDB" id="2895913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="20957" checksum="6B29783963927D45" modified="2023-09-13" version="1" fragment="single">FTTEINNVRRRITESSVEMVAMACHTDSHFTAFVYHLGHTNVEYGDSLHGSPPFDILPILQWIFGGLAAQLITGIVNGVIRRQGLGSGEGSCGVACHNFIERAVNARPGLNPWSGDRARIFRDAALEDLLQVNHIASLKEEEFHEWVVAALSQVERADEAEEQSLSIAVGFRDFNMYIPMVSIVTFNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E621</accession>
    <name>A0A9P6E621_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E621"/>
    <dbReference type="OrthoDB" id="3360976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="16"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="21908" checksum="EEFF7CEE73ED58F2" modified="2023-09-13" version="1">MRLYLSSRQPWRCDFAVPDGQVLYKTQSLRNSFGQERIIILKLKSSEIFEPLAEIEYHTDESHSRIKVGNRNLGAKKILRKEKWILFGYGERVFRGPDSHKYVWKMSSRKSQLFRKNNSQQPTATFHCPSSGFLSGSLPVSLEIFPQGEHMIDDILTTFIYMERMRTDMRGRFNLGVGPDANGDGGGGDGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6U9</accession>
    <name>A0A9P6E6U9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Frag1/DRAM/Sfk1 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_910586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6U9"/>
    <dbReference type="OrthoDB" id="68581at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000100">
        <property type="entry name" value="Unplaced genomic scaffold supercont2.12, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="640"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="675"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="305"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="364"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="3">
        <location>
            <begin position="502"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="5">
        <location>
            <begin position="746"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1033" mass="114090" checksum="B59A8608FEFF4640" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Y0</accession>
    <name>A0A9P6E6Y0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_886802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Y0"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="110"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="614" mass="70126" checksum="2DA07C66BB8A40D3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6Z6</accession>
    <name>A0A9P6E6Z6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_774930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6Z6"/>
    <dbReference type="OrthoDB" id="152248at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="19673" checksum="380127C6824BC60F" modified="2023-09-13" version="1" fragment="single">NVYNSTSLGVNGSGCPPGSTYYKISDDKTAVTVTFSSYYAEAGPTVATSQNRKNCQLTVGVAVPPGFTFGIANVDYRGYYQLDKDVEANQSALYYFQGLLTQASAQSTHKGPVDGNYYTYRDTFDLTSTVLSPCGVNTVLNVNSDIRVSNTKNKAGSGYIATDSVDTSLTTTFNFQWQTCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7X7</accession>
    <name>A0A9P6E7X7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_861789</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7X7"/>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="179"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9524127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="39142" checksum="36FD44568B40ADAE" modified="2023-09-13" version="1">MHLLFQNPILSTWTAHAISFGIGLTYVGSIYLSKNARLSFASKLKLAPGEATGNFPRSKLKEERWRDDPDVIKARMAAVSLATILICLWVLGILWRRVGGTLDVLEIATDATLLRLGFYPLSLSINPYQLLDLRSYSPHFVTPVLFIGPLLGSFLGGQLPGQRNWYWQSHIIARFFGLQGARNYWVGPITEEIVFRACVLSIYQLSGASKKKMIFLAPLTFGLAHAHHAWETYNRYGRTTAAAKRAILVTLFQLTYTTLFGIHVSYLFLRTGSIWPAITSHIFCNTMGIPEIGYELATYKRWKQVIIVTYLAGIAAFIYVLPRWTLTSDNLYWPSEPNTQHPFGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7X9</accession>
    <name>A0A9P6E7X9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7X9"/>
    <dbReference type="OrthoDB" id="2981375at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="26250" checksum="FB0606AB982503CB" modified="2023-09-13" version="1">MVTTPYDALSSGDSDKAIALLIANPNLATIYEFTQAFEQLCMKHPDKINIFASTLSSASQSDRISQFTICDADETLNEPFDGVFRREIYETIKRLLYTTADTSIIPSDKYIIASLISGVAILTNLCISDVQLIEIAQGLHFPRSKYREIFGEKKDEIKALGACIQVLVAGAVIYDGSEGRFTKQELKGRIPEVKRLMKHPTAIKVMEAVHRQLSTDESKSHTAGEVWQLMFPKAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E905</accession>
    <name>A0A9P6E905_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_860921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E905"/>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15522">
        <property type="entry name" value="PHD_TAF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="587"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="403"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="638"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="676"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="813"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="703"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="860" mass="96171" checksum="0B500B22D0D5ACCD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAJ1</accession>
    <name>A0A9P6EAJ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate dehydrogenase cytochrome b560 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_858915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAJ1"/>
    <dbReference type="OrthoDB" id="588261at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1300.10:FF:000011">
        <property type="entry name" value="Succinate dehydrogenase cytochrome b560 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9525806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="19560" checksum="54DAFBD97682A59F" modified="2023-09-13" version="1">MMSTRALGLGSALRKAALNPNLVRNQVAMRNIAGKRFIQVESLRPAQNIEILNSQRLKRPSSPHFTIYQPQLTWLLSIVHRGTGIALGGLFYGFSIAYLIAPTTFDTAHIVEVVAGLPEGVKYAGKALLAAPFAFHSFNGVRHLSWDLLKLLSLKGVYRSGYTVLGASAVATAYLTFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAU6</accession>
    <name>A0A9P6EAU6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mannose-P-dolichol utilization defect 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_859246</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAU6"/>
    <dbReference type="OrthoDB" id="271506at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000006">
        <property type="entry name" value="mannose-P-dolichol utilization defect 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="275"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="34240" checksum="69C802ABA4860B14" modified="2023-09-13" version="1">MTAITKNLPWFIRDLGISIVGEECYKSLVENLNVGDVKCLKYSLSKGLGIGIVLGGSIMKVPQILLITNARSAHGLSLPAYVLETLSYAITLAYSFRHDFPFSTYGENLFLTLQNTFITLLIIYYAPSRQLTGSGKTQKLVVATTLTCAMAFALHSVPIETLALLQMTTLPLSLFSKLPQIRQNLRSQSTGQLSAFAVISQIAGCLARLFTTATEVGDALVSAGFALALFLNIILGAQLWMYWGQGADLKDEIELKQRDSHVDDKPVNDVPVWQSQASSSTIYSPTATRLSSAPPTHRVATPPAAGGRKWARKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAU8</accession>
    <name>A0A9P6EAU8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator of RNA polII, SAGA, subunit-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_858710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAU8"/>
    <dbReference type="OrthoDB" id="10264870at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024738">
        <property type="entry name" value="Hfi1/Tada1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12767">
        <property type="entry name" value="SAGA-Tad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="334" mass="36975" checksum="099D3241699C63CE" modified="2023-09-13" version="1">MSLSSTSNLKGQLIKNLGLNARLYFDSLSSFVSGRTSRTEFEQVTKQVLTSANLLQLHNALIISLFDATATLKRPPSPPPPSLPKPPPSKRRRTLLPYQGPDIPDEQRTIRSGRLKKWALSVGRKERERIRALQTAPTTIEPMRPRREIDEIACERGVELLPERGDPPGSRLPIQLHSSTRAPTLQHVADRVNLISAQNNFATPARPVPAYLTLATEAFLKQLITHAITLSITSSTISSISPTSQNGSSHHFHLPKAQILTAASMNTLFTVSPADLPNKSAAAMRFALSPTSLDSETEDLLLLKDREVRDQRWQIMALLAERSTVRDSLKAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBN8</accession>
    <name>A0A9P6EBN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBN8"/>
    <dbReference type="OrthoDB" id="3212455at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="12157" checksum="72A43AEC530920DF" modified="2023-09-13" version="1">MFANGSLAVAIVRNQVMIVQAAREHTKRDKFVDVRTYTPFGAGVFLASEVPSARIASSAILTVLPPVENTDTDQGMLELSEPSFSRFIEHSSRHTKRHESLWNAWVSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBQ9</accession>
    <name>A0A9P6EBQ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1275 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_770960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBQ9"/>
    <dbReference type="OrthoDB" id="5288586at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37488:SF2">
        <property type="entry name" value="DUF1275 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="27373" checksum="F4A70C057656EDE9" modified="2023-09-13" version="1">MSIWQRLDQEVDPSGCLLPLATFCFMAGFIDSISFSATYVWCGFQTGNFAQLALAIARLWENPHRYFHIADQQALCSLISFWFGAFLGRFGARVGRQKRIWLIVGNLLAAMFMAIAAIAIWKSGQASVANHRDLPAWSNARTFVGIAGLSITLGIQGTLAKGLSSQLGTTLVLTTLWVELFNDLNLFKIGRVKGRDHRIIGAFCLFLGAFISRALLYEIGSAGTIGVGVGIKLINTFFWLWMPAKPTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBR5</accession>
    <name>A0A9P6EBR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_870367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBR5"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000006">
        <property type="entry name" value="Polyubiquitin 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="71"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="117" mass="13399" checksum="41CFAA5E6348D5B3" modified="2023-09-13" version="1">MQIFVKMLSGKTITLEVESSDDVDNIKAKIQAKEGVPLDQTRLIFAGKQLEEGRPLSDYNIQKESTIHLAKIRDQEEIPLDRQVLVFDREQLKDGKRLSSYNVQPRSVLLLVVLLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECE0</accession>
    <name>A0A9P6ECE0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECE0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="132" mass="14309" checksum="829F98309C973BF5" modified="2023-09-13" version="1">MTSEAAKELQDALNRFNALDTQALKDESIPVEKRAGAAKKASGDVLKAINKLDPLLKNAEQTQEIQEAQATLRKAEVQFTGLDSVLTNIHENEGGVEAYSFGDILRTVKDVVSHPIVQALPDAVWSVAKNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECE1</accession>
    <name>A0A9P6ECE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dcp2, box A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_794891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECE1"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1050:FF:000003">
        <property type="entry name" value="Decapping enzyme Dcp2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000003">
        <property type="entry name" value="M7GpppN-mRNA hydrolase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="117"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="261"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="331"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="370"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="692" mass="75425" checksum="312A70C2F0C63DCB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECL0</accession>
    <name>A0A9P6ECL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECL0"/>
    <dbReference type="OrthoDB" id="3193844at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="32430" checksum="042B292D17B06509" modified="2023-09-13" version="1">MDMSLIQDASDGASVKQRHPKYYIELVLFEVEDTLFRVQRDGFIRANPKFFDQFSLWSGEESSPIKLEDITAQAFEHLLMVLYPIGKDTPTYAEWLGVLYLATRWNMFEIRKEAFEALAALNEDNPRPIAEIIQLAQQYRIKRWLRQSYITLVQQKGLQLDALLLYLDPKTIMRIFAARTHLLERQPAVFVTDGKCNNCDKEDDWHTCMHCCFKKEQPHVFCSNCRATKAYWYCERYCRNRITPIALDDYSIVEAEVDKIFYEEFLEMEGLTIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECS8</accession>
    <name>A0A9P6ECS8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECS8"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="341" mass="37882" checksum="C75CBA0D640918F3" modified="2023-09-13" version="1">MSSAQPEAKRQKMAKVIGTHNGTFHCDEALAVFLLRQTSTYRDASLKRSRDPAVLATCDIVVDVGAIYDATKLLFDHHQRGFTEVFGHGFETKLSSAGLIYKHFGKEVIAQKHQLAEDDQKTTTLWLKMYKEFIEAIDGIDNGIMQYPNDIKPKYRSRTDISSRVGSLNPRWNQSTDSESVDVRFEQASLLTGSEFLGSLDYYANAWLPARDLLKSAISTSKSQVDPSGQIILLETFLPWKEHLFELEADSSYNAAEPGQAIYIIYPDETAGNWRVQAVPATPDSFESRKALPEPWRGLRDEELSKTSGIEGGIFIHASGFIGGNKTKAGALLIAQAALKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECU0</accession>
    <name>A0A9P6ECU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_430051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECU0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="11720" checksum="D4423A917E21A2FF" modified="2023-09-13" version="1">MNRGSRRSKRLKIQPEVKVRGQNVKMVTVRIPSMRQSMSGTLVSQSPQDAWFRNPCPRVIDATIVNYSENTICPKLARCIVMLPANHQVCSAPVLQIFGALLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECX0</accession>
    <name>A0A9P6ECX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_895552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECX0"/>
    <dbReference type="OrthoDB" id="3269282at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="570"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="677" mass="71165" checksum="9ED6786F1A75C648" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDB3</accession>
    <name>A0A9P6EDB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">XAP5, circadian clock regulator-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_816272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDB3"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="185"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="37863" checksum="545EF97F9C29A3E0" modified="2023-09-13" version="1">MSANKAEGRREDALVKERAKMREEFERQKATLIKETEKARPSSNRFVGQNDSVEDNLKNKTVGLMHLEDFQQRRKELEEIRAREAAKSSELKEETKKAKKRKKTAKAKLSFAMEDEEGGDEEPEDLKANDDEDDEEPRVKRSKLKKNPNVDTSFLPDRDREEAERKERESLRLEWIEKQEKMKKEDIEITYSFWDGSGHRKTVMCKKGDTISAFLEKCRAQFPELRGVSADNLMYVKEDLIIPHHHTFYDFIVNKARGKSGPLFNFDVHDDVRLLADATKEKDESHAGKVVERSYYQRNKHIFPASRWEIFDPEKNYGKYTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDF4</accession>
    <name>A0A9P6EDF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_895686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDF4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="142"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="32882" checksum="0D60BFBC8DC205C8" modified="2023-09-13" version="1">MFAIRGRSATQARKRSTLPSTQKENSQKDSSTSTNNVENSIIFCDNIQPGALATSELKEDIPMHNEDRGQQRCANQGKGLPTNLVQVGATHKEGVSFLNGAKDITITGNPSFNGYYHQYHHHHHHHHYYYPPSSLRYNPISGVTFVDLTGKEYSVSADHAVSRELFCKTIRLFFHGNIFEAYFQREEMEWGSYELIVVHQGTEIIKLDDKVWQSSFEVGMKVVMFPTFTAYQRYQCPHCHTWLVIDPELTAVVCGVTLILNQLKTTRDGSFLATPGNGLLKIKFVAPSRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDW8</accession>
    <name>A0A9P6EDW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_385124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDW8"/>
    <dbReference type="OrthoDB" id="3044561at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="33300" checksum="F4D3666A14EF6C89" modified="2023-09-13" version="1">MRHTAYLVSPDTASTMFIHQESCTPVACLVVLFLDTVSTWRVEYRAVWRQRKGLISAIYLWARYGALAALVVHNILAQIVLPRSTPPTIRQCSIWFSVVVVVCGSLSIGLEAILTLRVYALYGKTKKIWILVVPAGIQYGCCALFVYFRVLKLGAVPGFDSTCGLRTNVMEGMMPGFTTLIFHGLLYGATLAKRRVRASPTSPINRLIIQWVTREGTMAFALMIFIVTFVGPSMSVSRTIRLEFVFILPITFISLTTSRLILNMKTLTFECGSYCTVSEEFSPVSTIIQSLNASIEDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDY2</accession>
    <name>A0A9P6EDY2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_739952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDY2"/>
    <dbReference type="OrthoDB" id="3221808at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="120" mass="13575" checksum="ECD36157147182AD" modified="2023-09-13" version="1" fragment="single">TKQDHWNTVLEYISTKEKDRCNVWKDEVQNLLVFSGLFSAVVTALLVESYRDLEEDPNHALFRTMAVGIARLANMTEVGELPQAFAVSASTKRINALWFLSLVFSLSTAVISIVSLQWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EED5</accession>
    <name>A0A9P6EED5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Copper radical oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_856432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EED5"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040325416" evidence="2">
        <location>
            <begin position="16"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="3">
        <location>
            <begin position="73"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="4">
        <location>
            <begin position="457"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="633" mass="67476" checksum="1CA590BF44F7F167" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEL6</accession>
    <name>A0A9P6EEL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_792861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEL6"/>
    <dbReference type="OrthoDB" id="3235026at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="451" mass="50351" checksum="825FB3201E0EEF22" modified="2023-09-13" version="1">MASTTLLPNATWHGLPNELRLAIVDGLKADDVASLSKVDMTSYQATVPVRFRKIRLENYEALERFLENVPRSYFAYIEDLFLCTKSETVFRLPVLPRVRADSVIALLSATRGLVKLELQVQGSLDHSALSPFPFLNNLKSLSISNCGDECRTPLSERFVVSMAASARYLEELSLDRINRSKLHAPELEGTYPCPPLAINDDNIPDHPILGSELCLPSLLRLPTLRKLTIRETHLGHEGWSTVPLACRLEVLDLGSCYHANDDFNTEWTERIMTAVGTTVDEFSLTSTVSDTVFAKPSVTPLQRLRKLHITPHFPVDSVVETVSNLAGSPVERISVQCFEEDVVDYCTALEEFLTVRVERGPQFFDKLKQIDVAVTASEDAPTDEETEERCTAVKRLQDICRDLRLASAFDKFDKFVAYNASKAQAASGPVSYATSFTDSRRFPVKARSMSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEN6</accession>
    <name>A0A9P6EEN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_854943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEN6"/>
    <dbReference type="OrthoDB" id="2963718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040242903" evidence="4">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="185" mass="20118" checksum="2060872F911ADAE7" modified="2023-09-13" version="1">MRFILFIAASLLATLTAGLVIPVDSINEREIDDFEIIARAPIFGIKNPLKYHVKAGGGKPAQTYSRKEVKHAVKAARTEHARISAPGISNRQKKNSPLKAFSNNKHHAPKLFHSKKSIGGMKGSGHEYPLPNKAGAGKGPARVIVQANKAGKLKLKGVVAHDQKRTAGSPGHNDHFRVRPSIRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EES5</accession>
    <name>A0A9P6EES5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DHS-like NAD/FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_792588</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EES5"/>
    <dbReference type="OrthoDB" id="2919105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF8">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="10"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="370"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="504"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="549" mass="60217" checksum="F0132D3F9D15CF36" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF11</accession>
    <name>A0A9P6EF11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_855669</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF11"/>
    <dbReference type="OrthoDB" id="860at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN 25D9-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="225" mass="24597" checksum="D4BEDC17499E5DF4" modified="2023-09-13" version="1">MSAVPVTKNVNPLLAKYLVQLALHPLRTKALTTATLCFLQEVLGSNLSGSSPRIPKNASPTVRTLASVHLDAKAIKMALYGLLVSAPLSHYLIGLLQKAFAGKTSPRAKIGQIIASNLLISPIQVSAYLASTAVINGATSLDEVIKTVKTGFFSVIRISWLVSPLSMTIAQRFIPVELWVPFFNSVQFVLGTYFNIRVKKLRLAAAAKKQKEKERQDRENAERKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFQ4</accession>
    <name>A0A9P6EFQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NGG1p interacting factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_792051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFQ4"/>
    <dbReference type="OrthoDB" id="3345469at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1390.30:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1 type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602678-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="286" mass="31342" checksum="F3FFD0814F7EB047" modified="2023-09-13" version="1">MSNFLTKSVCEAMERIAPLRLASSWDNVGLLLESPVQRQGKRTIMLTTDLTTSVLDESVAKDTSVIVTYHPTIFRSVKALTLSNPLQASLLRCAAQGISVYSPHTSLDTVWGGINDWLAEGCIKNREDGEIRALSEERLNATSGKSEGAEGRLVTFREPILMGELQSRIKAHLKLTHVQVGYAFSKKPLTSTIRSIAICAGSGGDMLVGRNADVYLTGEMMHHDVLAAVAAGKHVILCGHTNTERGYLPLLAQKLRQELPLQDFQDQGLEVDILVSEQDRHPLEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG49</accession>
    <name>A0A9P6EG49_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit DUO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein DUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_854184</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DUO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG49"/>
    <dbReference type="OrthoDB" id="5599235at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013960">
        <property type="entry name" value="DASH_Duo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08651">
        <property type="entry name" value="DASH_Duo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="234"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="234"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="278"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9528457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="335" mass="37265" checksum="263625FCDE8A50D5" modified="2023-09-13" version="1">MDSPDINASHSGSRLLSTESPNFQSDSSNSRTGPGGDDLSLSELSLGPDSVMSKPFSLLARVNPPQPPTPTPPVFSPPPTIQDLVTPTRPQRQRKSEGKVFGPQNEQDAEESEEDEGEEQTVVLDEEVPVPEDPEVARKRTQELREEKLKSDMFVLKKLNASFELYRDALAETGSANERVAAQIAETDGLLNKYINILNKSEDYAKLIFDERWNGAEADEEEALREYQESIVRAKREAEEKARREREEQERLEREQEEQRKREERERIEKEKSAKAIRGTVRGVRGTRASTRGATSSRASATAGPSRGVPKRPPSATGRPAGSGIPRVSSVYRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGV4</accession>
    <name>A0A9P6EGV4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGV4"/>
    <dbReference type="OrthoDB" id="3187054at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="359" mass="38596" checksum="E331DA9901902908" modified="2023-09-13" version="1">MSPRPILKRSTPETAIHHQSSAQRPHGVHFPPSPSLTRTFHVDSKHVYDRSPIVVTPNSCALPARGCPGHTYFDEPTSPSSSTRRPSRKPRDYHPRALAFASDAVPQLIPDLSSESDESDGPISLSSSSSTSSTSSTSSSSGVMFGPHGLPANLASIKTTTMGLSMNRDMHTHGYAPVDADEDTHAQHALAFLPYSPSSPYPYEDSETLGAKGMEKHRRRRPSRERRHESMSSSTTTTNGSSRERERDSYRIPSGEVQTQECGFALAFSNLAISATTAYPSSPSTYSPSAYSPSTYSPSTPTYYPSAPSYMSSSPSTPTPSPKKRTSSRSSSRRSNPLPTSFGSGGFSSMSDDGCLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIZ2</accession>
    <name>A0A9P6EIZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_788099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIZ2"/>
    <dbReference type="OrthoDB" id="2355984at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="155" mass="17327" checksum="CFE08A58807D3E50" modified="2023-09-13" version="1" fragment="single">FSVDIKRSKEFLTSSPEVAVELNSFPSSQWERILRGQAVDLDQILSGLHGVQLAQVGKARIRNSQVDLSTPEPRRTVQTSTDWSVAFRKAADATSFIFEHRTVKLLLYAQYIESLFAAKIPASHGRVILYDKAVRSHVGGGHNISLTDYHKFSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ28</accession>
    <name>A0A9P6EJ28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_852247</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="948"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="1466"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="159"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="320"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="615"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="669"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="746"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="835"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="626"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="673"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="746"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="842"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9529813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1725" mass="194044" checksum="F0C0623B286A4059" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJG6</accession>
    <name>A0A9P6EJG6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="16">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_851122</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 18">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJG6"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 16 18" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="20">
        <location>
            <begin position="12"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9530182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="40583" checksum="9421465D69EFA539" modified="2023-09-13" version="1">MRASSLDLRYIAAPMVNQSDLPFRLLVRRYGVTLPYTQMYIADRLLEDREYLEYHLQDLSLASDNPYNRPVVAQLGGNDTDTLVRAGRKIQGLCDAIDLNLGCPQESARDGHYGAYLLPQKDWPLIESIVSAMSKSFTVPVSAKLRLCQPTNKTVDLAQKIEGAGASWITLHARTVSAKRRRQGAANLEEVKRLKECLGVPVISNGNVRSFSDLECNRNFTSANGLMVGETLLGNPCIFAGPTIPDPVDISLEYIYICKEYPGTSLKIVQTHIRHFVEFQCSRRSWFPKFRAALSATNSLDELERLLSFNVERWRGRFPRGYKSDDEQATPAELHSDIGDDPKGTGVLNDSSDFGLALFHPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJZ3</accession>
    <name>A0A9P6EJZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_198154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJZ3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="534" mass="58397" checksum="B6DABD4680DF0E19" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKA0</accession>
    <name>A0A9P6EKA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_762872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKA0"/>
    <dbReference type="OrthoDB" id="3059366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="19226" checksum="D83AB089EB36756B" modified="2023-09-13" version="1" fragment="single">MTTGSLFSASSPPAISTTRSPALHAFSTKFPNPTTPLLPAAPTPTPDSTSLPNPPSSPSKLPPFSPRKPISLTQPLFIPPPLTPEGIPSLAQGLVLIVRGVGAENPNSNAVSVMENTIKQIKASNPTLAETPLVVRPFSQRNDWTPSCYVHLDEDALRENETSPNPEPRVDLLEPWIDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKW1</accession>
    <name>A0A9P6EKW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKW1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20306" checksum="F33EA8D8BC2DC4DD" modified="2023-09-13" version="1" fragment="single">MSASASFFCHSRFSECQELSCSECKPVRLTSLRKSNTLEFRTFTILLPATPQGERFYDNLIVPLGQIPDNGIQSPDTDHDLSSTATARQPNDEVLPEMALNQMAVGLLSQQMAASFIRTLSLDSSEKLSTLLEDYAEVPKSESHLPLKSDATAASTRRPRASRNASSATETLKRRNRQSYIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELI9</accession>
    <name>A0A9P6ELI9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_760739</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELI9"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="96" mass="10022" checksum="72566D79448C95F7" modified="2023-09-13" version="1" fragment="single">GLGACGITNNDGQMFAAIAHEAFDTIPGVTGNPNNNPICGRMVTATYKGNTVTVPITDRCGGCDKKGSLDFSKPAFAQLTGGNFGLGRIEIEWTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELK9</accession>
    <name>A0A9P6ELK9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_874424</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELK9"/>
    <dbReference type="OrthoDB" id="5374328at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018287">
        <property type="entry name" value="Hap4_TF_heteromerisation"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF7">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10297">
        <property type="entry name" value="Hap4_Hap_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="63"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="55156" checksum="A67B8FCC08A20C5D" modified="2023-09-13" version="1">MTSIDTAASSSSSTLWATASKEWVIAPKPKPGRKPKKDVVPQVVEADSKGRRVQNRAAQRAFRERKQSQLADLQARIQAYEQGEIERNVALQKIAKQLKEENENLRQENASLKAKVVYLESQLESLPPEPRIFDNPSNVTDKKRGREASPSAIGPPFPPKKRSRKDSTAVLERHTSMISESSGTTHLPSPTSMVSTPDSFETIDQFPPLSFEPSQGADSNTFSSLSSDAKSDIPLRAFPFDCGFCDETTICVCREIAAQAVVEQSLITPNYTGSTTSRAAEEPPSSIISGAASSKSILENLPTYQPPVPLRRRTKTTISNSIFPVHAPAAEPPTCSGDPSNCMACADDAFGKAFCSAIGSSATTCDCSAEVISRCCGGTSDCNDCPSSNAAIPPTATQDQSELMPTNDAWQKIKAHPKAEFADLALLAKVVASQSKCAGPQLVITPTPQTHVHEDEILQATKNPPGNRGNRSPPPQLVPQEVLLECGRRRMRQVHSSGVYEALRLLDAKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELU7</accession>
    <name>A0A9P6ELU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_892235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELU7"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="33540" checksum="839730DFECCC9A6A" modified="2023-09-13" version="1">MNLPPGVVYLTGVLPYLLWPPLATYAVLRAAHQALDISTPTWLLVASVLLARPTLSMIQSRYKDYQDRIAAERLGAVLPPLRGKALSSMKDMLDMIMNGFPGDIFDLWAREHGNTFFFDKLTSRGIITLDPDVVKALLATQFDSFGKGEEFIGQMDSLLGSGIFNADGEMWKFHRAMTRPFFTKERISDFEIYGRNSDISLALAKERLKQGEPIEFQDLVGRFTLDSATEFLFGQSVQSLAAGIPYPPTSSRKMPSSFASHPSNIFVDAFVGGQRVAVERTALGFEWPLREFWRDTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM16</accession>
    <name>A0A9P6EM16_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_867605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM16"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040302375" evidence="6">
        <location>
            <begin position="23"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="476" mass="51703" checksum="400F41C052434464" modified="2023-09-13" version="1">MHLSLRHIFLCLSVALNALCAGAMFTFPLISPILGRHCKLTQPQLTTVVLAGMMSQYTIAALVGWIIDNRGPHCCSLASALLFATGFGGFAWEIRSTPNDILEPVYGAFYRLTFCFFLVGLGTVFAYFSALFAASKSFPNHLGLASGASMGLFGLSPLFFSVIATSCFTDVNTGLLDVRRYTTFLGSATFIVYIAGFIFLQGVPRMVGSISHQEMQAVADDSMIVETTPLLQTSRSSSFSKPSELSVSELLRESDFWLLVLFAVLIMGMCEMVISNIGTIVASLPATSGTRQSILESSTAFQVNLIAASNTLTRISVGPLADFVSPIAAYLPTGIVFPTKHRISRFAFLAGPSLLLALTCAWMVYGVEHQGQLWLLSLGTGLSYSSVFTILPSLISSLWGMQNMGRNFGLMMYAPFIGTPTFSYLYAFVSARYTPAGIGICSGRACWEPTFAFSIVSSFVAFTISCIMWRRWKGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMF6</accession>
    <name>A0A9P6EMF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_109509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMF6"/>
    <dbReference type="OrthoDB" id="3057032at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="593" mass="60225" checksum="706419F17F5F8280" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMJ9</accession>
    <name>A0A9P6EMJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_760967</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMJ9"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="37281" checksum="8350D35F2A31F125" modified="2023-09-13" version="1" fragment="single">VVAVTYGITIKSVQDEYIIMTERTMDLIGKATVPGANLYDLIQIIKYLPAWLPFRREAAEGRLMIEELVSKPFYQTREDISRGFASHSLVSEVLVSEELTPRREAVVKWAAGSLYGAGAETERTYATVLTFIMVMALHPEKQKLVHAEMDRVLGTGRMPHIQDRNDLPYLDAVIKETARWHPILSLSALGIARQTNTGDWYKGFYIPKGTIIVLNVWAVAFSQNDRYNPQDLIPETFLDNDFPEIDPASWSFGFGRRVRPGKAFAENLVFILIASLVWSFTFSVNDSEVFVPQFTENLVSYPKLFKCTITPRSDHHTKMVQDAAMEGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMP9</accession>
    <name>A0A9P6EMP9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_806920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMP9"/>
    <dbReference type="OrthoDB" id="2317741at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350846" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="37"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="15119" checksum="8AD15E4C349B06F7" modified="2023-09-13" version="1">MKLSIFATLATVFVAGVNASAVIKRAAQDVYSPHITSPTAGVVWTSGQTQTVTWDTSDAPAHITNRIGRIVLRKGATTTPLVLADNFDILDGKAQVTVPNVVAGSDYEVVLFGDSGNISPEFTITGSGLAAGTGLNKIRALPHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN60</accession>
    <name>A0A9P6EN60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN60"/>
    <dbReference type="OrthoDB" id="5987198at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="22939" checksum="FA4D6AB01D7E2548" modified="2023-09-13" version="1">MTSTLSQTTITQSLSTMMQKLILFRLTSISTSDIILTHCISIDFLEASPLPNRTSKLNTTSDGDSFDHRTDLQKYNHCLPVLNELTLSDVDVNDEFLCRSADSRDDSGTVSLYKILVHPMIRPWCSPGFETLGEVLDFLWQAFIGLQFIHKHGVALRRDLLSDMLMEADEMFPEGYHFIMRTVDPTFKHLAKYLGPEILSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENB7</accession>
    <name>A0A9P6ENB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Man1-Src1p-C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_846638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENB7"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1180">
        <property type="entry name" value="MAN1, winged-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025856">
        <property type="entry name" value="HeH/LEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018996">
        <property type="entry name" value="Man1/Src1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041885">
        <property type="entry name" value="MAN1_winged_helix_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12949">
        <property type="entry name" value="HeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09402">
        <property type="entry name" value="MSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="656"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="HeH/LEM" evidence="10">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Man1/Src1-like C-terminal" evidence="9">
        <location>
            <begin position="371"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="791" mass="87071" checksum="FA755DC5BAB2C1ED" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENM1</accession>
    <name>A0A9P6ENM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isoprenoid synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENM1"/>
    <dbReference type="OrthoDB" id="270318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="37163" checksum="EA358CA9DEE13C0B" modified="2023-09-13" version="1">MRLCARILTRQNRQSNLFRQAKPLSTPNRRTVSTSTSTVGLTDPHAYCRDLVRKHDYDSYLNSFFYPSETWNVFFAVKAFSVELATIQDSVSNAAIGRMRMQFWRDAVKGISDDRPPKHPVALALHETSKRHKIPAYHLKRIVDARDAELSNPGHMTVDSLTAHAESTSSTVLYILLSILSLSASSAYSHAASHLGAAQTFSTLLRALPYHAKQRHLVIPAEITSKHKTVQEEVFRYGPEANGIEDAVFDFATLAHDHLVTARSMLVNEEGTNGKIPKEAMPVFVAAVPVSNYLKRLEQSGFNAFDPKLQRRDGWLPLQMWRQNFRRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP43</accession>
    <name>A0A9P6EP43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_873448</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP43"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000041">
        <property type="entry name" value="Chaperone protein DNAj, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="127"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="398" mass="43774" checksum="E7FFECFE764BC6BF" modified="2023-09-13" version="1">MVRETKYYDLLEVSPTASESDLKKAYRKKALRLHPDKGGDPELFKEVTHAYEVLSDPDKRSIYDTRGEAGLSEQGGMGGMDPQDLFSQLFGGGGSSFFGGGGRAQGPRRTKDLVHRVNVSLEDLYKGKTTKLALTRNVICVKCKGKGGKEGAVRSCSTCHGRGVKVTLRQMGPMIQQIQSPCDDCSGTGETINPKDRCTNCKGKKVLPEKKFLEVHIDKGMKGGQTISFRGESDQSPSAEPGDVVIVIEEKAHDKFRRQENNLVIEVEIDLLTALAGGQFAIRHLDDRALLVNIEPGEIIKHGDVKVIRGQGMPSQRHHEPGDLYVKLGIKFPDSLDPSTIPLLEQALPPRAPIETFDKNIVLEEATLDEVDARTSENIRDDPMDEDGEEPRVQCANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ32</accession>
    <name>A0A9P6EQ32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TRAPP II complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_890650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9533009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="27962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058567">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26280">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26282">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040511886" evidence="3">
        <location>
            <begin position="28"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="5">
        <location>
            <begin position="367"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="6">
        <location>
            <begin position="694"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 third Ig-like" evidence="7">
        <location>
            <begin position="1044"/>
            <end position="1209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9533009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1339" mass="147993" checksum="5F30A80D0FE9537C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQF5</accession>
    <name>A0A9P6EQF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">UMP pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_843788</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQF5"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000003">
        <property type="entry name" value="Uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="UPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF4">
        <property type="entry name" value="URACIL PHOSPHORIBOSYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="23135" checksum="C6DB6BE26C6CC899" modified="2023-09-13" version="1">MSSKLLNVLDHPLVNAELSKLRQKNTSSKEFREAVDTISLLVGYEASRSLGSESFQAETPVASFTGTKIKPRVGLTPILRAGLGMTDALLRLFPSAPVYHLGLYREKVSLQPVEYYSKLPPSPPVDQVFLLDPLIATGGTACAALSMIIDWGIPAKNIKLLAVLASKPGLEHVQKEHPDLEIWVAGVDQELTGNGIIKPGLGDAGDRLFNTLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQS3</accession>
    <name>A0A9P6EQS3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein Spc24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_783110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SPC24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQS3"/>
    <dbReference type="OrthoDB" id="3344830at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11565">
        <property type="entry name" value="RWD_Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013252">
        <property type="entry name" value="Ndc80_Spc24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038066">
        <property type="entry name" value="Spc24_Fungi_globular_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08286">
        <property type="entry name" value="Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9533496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="21341" checksum="A8E688207C1EE8DE" modified="2023-09-13" version="1">MIDVQEATKVIRDMLPVMDPEEDYMTIVAAEEKIGASEALRKKELEEAHATLKALSRTLDAARVSSTRPASVPSEGAHTATLNELDGTRLSLAKAISDSEALVASREAELANLKEEARRLELYDPENEHEKQLDGSALRLAIYKGLGFTPVMDKKGNVVKMLVRSQSGDVHTVDLTTGKSDFEYTQQLWKLVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQT4</accession>
    <name>A0A9P6EQT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Patched family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_902320</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1640.10:FF:000029">
        <property type="entry name" value="Putative Patched sphingolipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003392">
        <property type="entry name" value="PTHD_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02460">
        <property type="entry name" value="Patched"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="696"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="724"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="844"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="913"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1191"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1215"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1240"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1286"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1327"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="11">
        <location>
            <begin position="683"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="759"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="762"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1388" mass="152877" checksum="B0D683DD3897005D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESF1</accession>
    <name>A0A9P6ESF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_841494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESF1"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="6">
        <location>
            <begin position="69"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="37298" checksum="B382263B1A359AF4" modified="2023-09-13" version="1">MPKVSISSFPVSGLFGVVKPTGPTSMSIVNDLQQLIARSKLFVDAEKLEKIKGKKIDRKRGKFGKEGVKVGQGGTLDPLADGVLVIGVGRGTKKLNEFLNCTKEYRTTCLLGCETDTYDSEGSRVRVAPWRHVTRDRVESNLTTFTGQIKQVPPIFSALKMDGKPLYEYARKGIPLPRPIEARDVTVHSLSVTEWLGSQHPYTWPDKELSSEEKQALEAALKGVEEGAKVADELEPIPANFEDEKPSAFVMSMKVSGGTYVRCIVHDLSHAVGSAGHVVTLTRARQGRFVLASKEDEDRECIPWEVFERALSDVGEQDDEGWTEWERQVMEHLEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESF4</accession>
    <name>A0A9P6ESF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleotide-sugar transporter-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_841491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESF4"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="398"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="450" mass="48480" checksum="A60F2B484C20A2A7" modified="2023-09-13" version="1">MSPRGSQELDDDVKLPLPIAVSAPAVPSLWGIPLKYLSLVTLAVQNSSLTIIMHYSRVSTPPERTYSAATAVLMNEILKAIISLVIAFYGVDTSGMSSEVGQAPHTSPSRLALRMFGYRLTKLRKDVLSRDCWKLSIPAILYVIQNNLQYVAASNLEVATFQVSYQMKILTTAAFSVLLLRKKLSSTQWLSLVCLAVGVGIVQIQGSTGSSHSVVESAHAMNSLTGFSAVTAACFTSGLAGVYFEMVLKNSQSDLWVRSLQLSLFSLLPALAPVIFNQRAQMADNGGNLFSGLFYNFGAWAWATVLTQVLGGLITALVIKYADNIMKGFATSLSIVISFLASVALFDFRLSVTFLLGSTVVLIATWLYNHQPARATSARSIGAMVSDVWISLKSEEGWKDRNPGSQRSGTPNKAFVAHTASSSSSLSIPLLPPSSSSSTPSLESEKTIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET34</accession>
    <name>A0A9P6ET34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_844112</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle</location>
            <location evidence="5">COPI-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030663">
        <property type="term" value="C:COPI-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000002">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="7">
        <location>
            <begin position="761"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="635"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="706"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1146"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1612"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1615"/>
            <end position="1625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1855" mass="207258" checksum="A53E52181293ECC3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETD5</accession>
    <name>A0A9P6ETD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Inosine triphosphate pyrophosphatase</fullName>
            <shortName evidence="12">ITPase</shortName>
            <shortName evidence="12">Inosine triphosphatase</shortName>
            <ecNumber evidence="12">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="12">NTPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">XTP/dITP diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_842697</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ITP + H2O = IMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:29400"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-hydroxy-dATP + H2O = N(6)-hydroxy-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:83971"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:233529"/>
            <dbReference type="ChEBI" id="CHEBI:233530"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:83972"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>XTP + H2O = XMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:28343"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="12">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="12"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETD5"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009204">
        <property type="term" value="P:deoxyribonucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.950.10:FF:000003">
        <property type="entry name" value="Inosine triphosphate pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03148">
        <property type="entry name" value="HAM1_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027502">
        <property type="entry name" value="ITPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00042">
        <property type="entry name" value="RdgB/HAM1 family non-canonical purine NTP pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="70"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00093218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00093255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00093271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9534659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="20540" checksum="7DEA9851F5B8B1DF" modified="2023-09-13" version="1">MSNTTPLVFVTGNANKLREVKDILSQGGNSIEIESRSLDIPEIQGTTIEVAQAKCRRAAELINGPCITEDTALCYEALNGLPGPYIKQFMAEIGHDGLNKLLVGFDSKKAEAVCTFAYAAGAASEPIIFEGRTEGTIVCPRGPKVFGWDAVFQPLGYDQTYAEMPSEEKNKISHRGKALEKLKAYLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETI9</accession>
    <name>A0A9P6ETI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Pheromone-processing carboxypeptidase KEX1</fullName>
            <ecNumber evidence="15">3.4.16.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Carboxypeptidase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Pheromone-processing carboxypeptidase kex1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_203665</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Preferential release of a C-terminal arginine or lysine residue.</text>
            <dbReference type="EC" id="3.4.16.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.6" evidence="15"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETI9"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000121">
        <property type="entry name" value="Carboxypeptidase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF190">
        <property type="entry name" value="PHEROMONE-PROCESSING CARBOXYPEPTIDASE KEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4 21" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0732">Signal</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040479673" description="Pheromone-processing carboxypeptidase KEX1" evidence="20">
        <location>
            <begin position="26"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00040403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00040628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9534582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="567" mass="63626" checksum="BA9019FFA25776B9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETV3</accession>
    <name>A0A9P6ETV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_901698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETV3"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="101"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="254" mass="29229" checksum="23AC223D56721C61" modified="2023-09-13" version="1">MAKTQDPDHLIIEVVEIQEGLEGRMHQESLRLLDRVTVEAFRLGDIPRGIDNFYDAFGPDPMFRYTGGTVPPSILHKTIMRYNFMTWTWTSIMLTIHHGVAVLRASPPHRTCLLERLLRGLIRIISGPMRLLLSAEQKKRNEEVDMKMKQLNKDAGVEEKSKDWVYLEMLFTAQKYQGQGFGSALVKTLTTWLDLSGQTSWVHALDSNEGFYNFHGFQTMGSITIAEENPEWHEDPFTLIVMVRYPKSSEIEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU40</accession>
    <name>A0A9P6EU40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_888206</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU40"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000001">
        <property type="entry name" value="zinc finger CCCH domain-containing protein 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000002">
        <property type="entry name" value="Zinc finger protein 36, C3H1 type-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="535"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="573"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="535"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="573"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="169"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="601"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="736"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="809"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="609"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="650"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="825"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9535500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="848" mass="91639" checksum="E2BE196EBD072523" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU74</accession>
    <name>A0A9P6EU74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1909-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_901262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU74"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="38"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8109" checksum="9488737F1914FAA9" modified="2023-09-13" version="1">MGNGAKAAQKRERNAAKNDPKGSKSQAKVNEAAKNIVCSTCKQTFLLTTRAPALEEHSQNKHSKTMAECFPTFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUA7</accession>
    <name>A0A9P6EUA7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUA7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="56" mass="5899" checksum="FB9E060AC7A09073" modified="2023-09-13" version="1">MFEPISATSFVAVYLAVLVVSVGVAIVTAPPGEYVSFHFSRAGKIFVKQGLLIASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHP3</accession>
    <name>A0A9P6JHP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158006">
        <property type="protein sequence ID" value="KAF9521656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHP3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="12336" checksum="E7807264FB735D5C" modified="2023-09-13" version="1">MALDRHPNIFFPPRTEQPCELGVIADYLRRGLLSPPRSYFDGESYQGVIRRLRNNIPLPPIILSENASDPTQPHLCIGGADVLDALCRYPPLTPHQVAFFRDMYDDSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ14</accession>
    <name>A0A9P6JJ14_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ14"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="578" mass="64919" checksum="7A207EA67B7063ED" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ16</accession>
    <name>A0A9P6JJ16_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_94807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ16"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="54555" checksum="EF3B1476AA596AD5" modified="2023-09-13" version="1">MDLPPEIWFQIVSLLTDHEIWPLRCLNRVLWTTAWDRQCATLYLDTLEMTKERFWRNLRRLQSHHVVHRVREIIFSRGEYHSSVLWRVLVQERKVGYLAGFNDFIADLSERRDDLIKRIIVGFPNVSSLRVSYSDSGGQLFTLRPHLPLFRFTLELYAARLRSLTISLHSLWVAERVHCPRLEYFSVNTYHPDPNPASTTDMSLPRNTIDGWIILFLNMHRQTLSTFAFTTLNHDPTVDDLFMKTKHIPNLRVLTLNLVILTPKGRSSLHRFLTLHSSHLSEFNFSLKGVRSKPADITPYLFGMDKTTLSNLNQLSFNLSNITIEPLVAELLVFASEHASNLSNFGIHQRPLRRWEWQMFITPSWTRLAHLALVLYELTASDIDIIATQFPSLQSMLLDVFIFSGKSMEVMSEPSQFGIDINERYYTCSSLRYLTMPRGEEHWPAIAKAFPSLLLLNDEPRHLYLTGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK64</accession>
    <name>A0A9P6JK64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK64"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="48590" checksum="CDB500987D6E15C1" modified="2023-09-13" version="1">MAFVKYNYPQELIDMIVDNVADGNDVQCLRACSLAATAFQQRAQMYLFRTLKFYDLNFWTPASWVSKLENLSLALTIHPHLARYTRGLRLQHGPDVNPWLYSNHTFLSIVEQLDNVEDVFIRQRNYGTFTQLEKLFDSFWKPFIQPRVKKLRLDRVWDFPLVLVIACPKLESLGLHSVKFNESTLKDISQLLGPSPPKSRALTYLQFRGGPIIHEFVQSWRRENVCDLIDLTKLSTIDCFFRFNHSGDESNWLNAILRSTRTSLKSLILGGRIVNPDESQISLRGLVSLKEISFCIEDFEPGWALGKYYPVQAISEIFATISDDSPLMNLEVATKLTKDPLRSLRWLLDQTSWVNLDDAINSWQERAKVLTRLTMRLEYRKQDMNSEDVASLLQEYERIRVDKLPLTNSNTLINVSILSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK97</accession>
    <name>A0A9P6JK97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_862555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157913">
        <property type="protein sequence ID" value="KAF9523655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK97"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="103"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="619" mass="70704" checksum="B17F6EBD9860520B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKF4</accession>
    <name>A0A9P6JKF4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_949528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKF4"/>
    <dbReference type="OrthoDB" id="10265862at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061503">
        <property type="term" value="F:tRNA threonylcarbamoyladenosine dehydratase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061504">
        <property type="term" value="P:cyclic threonylcarbamoyladenosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="1">
        <location>
            <begin position="100"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="53358" checksum="E514771A1E2088B4" modified="2023-09-13" version="1">MSNLSHRTQLAATAVGASVLTFGLLQAYNSYSRYSKRKALDQEIHRSLNAHDFPGPVERDEITSEVNDYASLSTENEFSRPDKLGVPLEYDEDLIREQLARNYAFFGEDGMKKVRQGSVVIVGCGGVGSWAAVMLARSGVSKIRLVDFDQVSLSSLNRHATATLSDVGMPKVKCIEKALNKIAKWVEVDSRIELWRKDEGNDLLAGVDWVVVDLLKYCHENSLKVFSSMGAGAKCDPTRIQISDISFTVYDPLARSVRRRLRLLGVESGIPVVYSTEVPGDVKLLPLPEEEFQKGSIKELGVFDDFRVRILPVLGPLPAIFGLNIATYVTCELAGKPISNPLPIKNRKKVYEKLYRDLLHRESKLAGHQINKLPIDEDDVALIFEDLNRGRSIVPPHDVPSRPALVRWDSTRPLSIDNCVVFELSEAEKHVRECWDTQGRPKEGVRPEKLWGQEVASIVEKRRQEVKRLREWLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKN2</accession>
    <name>A0A9P6JKN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_729869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKN2"/>
    <dbReference type="OrthoDB" id="3267074at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9364" checksum="48C2937D5C905ABC" modified="2023-09-13" version="1" fragment="single">LHRIGKADSPICQRCKIEDKSVHYFLVRCPAYCQQRDQLSRNAGYSATYMTNLLSDQKLQKHLILYLGQTRRFKTVFGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL05</accession>
    <name>A0A9P6JL05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL05"/>
    <dbReference type="OrthoDB" id="109543at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="13"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="716" mass="81355" checksum="72B20C114B38FDF5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLL6</accession>
    <name>A0A9P6JLL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS Git1p-related glycerophosphoinositol and glycerophosphocholine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_860592</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLL6"/>
    <dbReference type="OrthoDB" id="2261376at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
        <property type="entry name" value="Putative MFS phospholipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="479" mass="51757" checksum="FEC5FAE3C3ADDA00" modified="2023-09-13" version="1">MSVTFKQKLKSVSLIFACGTALFSDGTCPLLTRIYGKEALAAHNYSQTLSSLAFAGTIVGMLSFGYLSDKFGRKFGMMTATVIVALFSLLSACSAGKTVGGLLSMLSAMRFLLGIGVGAEYPCGSVSASEQSEEPGIGKKAQNRWFALATNSMIDFGFVVSAFVPLVLYWIFGDNHLRAVWRLSLGLGVVPALGVFIWRLNMEEPARYKRDSMKHAKIPYLLILRRYWVPLLAISITWFIYDIIAYFGLYSSIVVDGVTGGSTSLVVVFGWNVVINLFYMPGTLVGAFVVDYLGPKYTMILGLVLQAIIGFIMSGLYTHLTKNIGAFAVVYGIFLTLGEFGPGNCLGLLAAKSSPTGVRGQFYGTAAAIGKVGAFVGVWVFNPLIDAFGGPTSEKGNTGPFWVASGLAIVSALITFFFVKPLTTDGMAVEDEEFREYLRQHGYDVSQMGLVEETSSHGSFEDEKHEKHEAKGETTVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLZ6</accession>
    <name>A0A9P6JLZ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5563754at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058155">
        <property type="entry name" value="Skg3/CAF120-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25381">
        <property type="entry name" value="PH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="189"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1344"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1532"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1589"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="689"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="748"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="781"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="834"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="920"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="935"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1344"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1384"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1400"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1539"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1596"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1627"/>
            <end position="1653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1682" mass="178812" checksum="D32D83810BE663D9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM60</accession>
    <name>A0A9P6JM60_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_772038</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM60"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="296" mass="32265" checksum="852C417E319B19C9" modified="2023-09-13" version="1">MESVEHIEHEHQEEIPPTHTEFPNRWARYRNFLREPFAEFFGTCILIIFGTGVDCQVVLSGNPSVAPSAKGEYFSINIGWAAGTALGVWVSGGISGGHINPAVTLALAVFRGFPWRKVPIYILAQVLGAMVGAAVTYGNYYHAIDLFEGPGVRTLKTAGLFSTYALDYMTNVSAFFDEFLGTAVLLIVVLAMSDKKNLQPPSGLAPVVLFVLVLGIGASLGMQTGYAINPARDLGPRLLTAMVGYGKEVFTFRNQYWIWCPIMGPILGALFGAFVYDAFLFTGEESIFNKPCVPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMU5</accession>
    <name>A0A9P6JMU5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AEX-3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_770250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMU5"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF31">
        <property type="entry name" value="DENN (AEX-3) DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cDENN" evidence="3">
        <location>
            <begin position="468"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="927"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="800"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="927"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1048" mass="115009" checksum="A05C62EBB4B5B610" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMX8</accession>
    <name>A0A9P6JMX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_908665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMX8"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="306" mass="33235" checksum="A37B37A9507C417F" modified="2023-09-13" version="1">MSKSGIKNVLIAGASGTLGPPVLTEFLASGKFNVFALVRLESKFTFNDKVKILKSDYTASSLAALFKAHPIDAVINMISWKSSETEKAQMTLIDTSKAAGVKSFIPADFGNDLSIPEVLDLCPIFAGKARAIEYLEKVQDGGFSWSTIINGPFFAMCIHSGLLGVNIKAKRCSMFGDGSTRFSTTNLETTGKALVSLLGDPTKLAATASRRVYIASHTITQKELFVALEKVSGEKWVAEWKNLEAAERDARERYSKGDRKAGFDMLEISTIKGGHGDYSSKLDNEFLGLPEDDLEADIKQVLAEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN12</accession>
    <name>A0A9P6JN12_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_857986</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN12"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="843" mass="91938" checksum="23019CC71A5B5BB9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNP8</accession>
    <name>A0A9P6JNP8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_884036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNP8"/>
    <dbReference type="OrthoDB" id="3068592at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="502" mass="57966" checksum="20D0A41A8D4151B9" modified="2023-09-13" version="1">MSLLRTSAHWWHFITSRVISSPLYVFSLLRKLHLFRSLSWSTPTSKDVTSKSSQKVLQELPVELLTELMRYLEWYEVLSLRQTCKRIHAASQERAIWLTLLQRYIKTVEPRAYWPDRPLNFYNSQELESLVLRRHQVASSWSKPDSSPSLHRQFLAPNRRIKTSYLVRGGRWFLVTNTQGDILYFDLDDTEATARILIPSRYPPSTKVYLHMSVDMDNDAPFLTFNLAAQVQCYVAGHQNFNSLFQIWRITPKINECGRIVDLVADNKASFMEEKDVEISRLSLHGSYITYSIEHCGTGRRFTCVVDWTMTSETSLSYRRNLIAEMFDWVTFLPDNWLICNRDAYLHLYHLSDLPETTLPISQCIRPNTSPRRELALYSRNFSEAFTVRDSQRHVFSTCNKVMGIIFPHQNPVDAEVVTLYQDGVLLDGAQLAYNFAASMITEPKLSILHYSWPEIGTGGGATSKEYTLLKRPHRIHLDEVSGRLVISGGSGQVYNVVEFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNX8</accession>
    <name>A0A9P6JNX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-ribose-5-phosphate ketol-isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_428338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNX8"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006014">
        <property type="term" value="P:D-ribose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000014">
        <property type="entry name" value="Ribose 5-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000053">
        <property type="entry name" value="Ribose-5-phosphate isomerase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001924">
        <property type="entry name" value="PRK00702.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934:SF0">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="31625" checksum="07E4D5E10C6E256D" modified="2023-09-13" version="1">MQKHPHFRSQFIKSCVSRFRTEHSSESAKSSMGIPLADAIEQSKRLAAYQAVDNHVLPEHKVIGIGSGSTVPYVVERIIAQGKEVNKGRVFIPTGFQSKQLIVDGGLTLGDVDQYPTIDVTIDGADEVDHALNCVKGGGACHLREKVLAEAAITFVLVADHRKNVQYLGTNFAQGVPIEVVPFAYAKVLQNLHHALGSPKATLRMAVKKAGPVVSDNGNFIIDAPFGREHMNDPYTIMARIKMLTGVVEVGLFCKMARAAYFGNADGSVTIRWNDGKVETINAEQVSEKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP48</accession>
    <name>A0A9P6JP48_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_907710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP48"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="60757" checksum="4F8DC8B0C7D2F1D3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRX2</accession>
    <name>A0A9P6JRX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glucanase</fullName>
            <ecNumber evidence="11">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_868098</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="11">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="11"/>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRX2"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.40:FF:000001">
        <property type="entry name" value="Glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF2">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 11" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040544505" description="Glucanase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 10">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="389" mass="41260" checksum="62EF04B495D2E60A" modified="2023-09-13" version="1">MKFSALLAAVTLATGAYALPANETVEKRATCSPVTLSGNPFTSRKLFANSHYGDYVKTAAAAITDSTLSSQALKVADVGSFLWLDTISALDTLDGHLKSVPCDQVIGIVVYDLPGRDCAAKASNGELAVGQLSTYKSSYIDALVKIIKANTGTAIVALVEPDSLPNLVTNADLSTCKASKTGYEDGVAYALKSLNLPNVVQYVDAGHGGWLGWNDNLKPGAEELAKVYKAAGSPKNVRGFATNVAGWNAWSKTPGEFENAPDGQWNKAQDEKRYVSLFSAALKTAGFPNYAIVDTGRNAVQGLRDEWGDWCNVNGAGFGVRPTSSTGDSQTDAFVWVKPGGESDGTSDSTANRYDSFCGKADAYKPAPEAGTWNQAYFEMLLKNAIPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRY1</accession>
    <name>A0A9P6JRY1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRY1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="663" mass="71952" checksum="FAB77AA97CDE4907" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS74</accession>
    <name>A0A9P6JS74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_748578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS74"/>
    <dbReference type="OrthoDB" id="2505969at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="17803" checksum="C089EF5E5EDC93F2" modified="2023-09-13" version="1" fragment="single">KRMWNVFDESGLFASACRHGLILWIADLVQSGELAKYPLAIVDQALNVLGDRLLVGYDIGCSFSKTVANSQLGSKFKASRSRFCVNAFHGYSHNFTCQKENHPNVIKGIGIEDLETLERVFSASNALASVTRNMSAYRRRVFIDLFFKQWDADKYANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT24</accession>
    <name>A0A9P6JT24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT24"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040106757" evidence="2">
        <location>
            <begin position="21"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="36979" checksum="BF07BDCB9B5D6090" modified="2023-09-13" version="1">MVQISTALFFATLAITPLLAAPAVESITQDIQAREPEQASENISLAAREPRRFPGAGGRRGSGRRFGRKAAAASSEEARELDDSLEEVEAREPGRFGGGRRSGGVRRGGGRRIGRKAAAAAPSEEARELDEDLEIREPARGGRGFGGGRGRRGGRRFGKKAAAASEEAREVDEEVEAREPGRFGGAGRRSGGGRRGGRRFGKKPAAAASEEAREFDDELDVREPRGSSGGHAGHGGHNHPRELNFEEVEAREPGRGGRGFGGGRGRRGGRRFGKQAAAASEEAREFDDEVEAREPRGSSGGHAGHGGRNHPREFEELDARGHGQHNGGKGGGHHRRELEATVYDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTJ5</accession>
    <name>A0A9P6JTJ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_903990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTJ5"/>
    <dbReference type="OrthoDB" id="3246846at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="2">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="75" mass="8344" checksum="33F83755CE615A70" modified="2023-09-13" version="1">MPEDTGTSRLNAYLQGQQKLRVVTYAETQAVLNNERFWTVVCKIDGVARGTGTDLKKSTAKNMAADQAYEFLSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTX3</accession>
    <name>A0A9P6JTX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_807425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTX3"/>
    <dbReference type="OrthoDB" id="429967at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052565">
        <property type="entry name" value="Glutaredoxin-like_YDR286C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558:SF1">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="387"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="451" mass="50934" checksum="7D05B35E0F6AE90D" modified="2023-09-13" version="1">MAIRGARLPKFTLFTGPNCSLCDTAKSALAKVRQSRPFQLDTINIQDPGQEKWKKKYVYWIPALHLEDKEVVKGRWDEKAILQALKSWDQNHTQGETGVSSYYTFGSKASTLTSTPFFYHSNPGPYSHSWEQSGVYQRGISEDEGFLGHSEDETVKDDIVDTNNARCFNCGDPEHKVPDCPSRPNRDLIALSRQFYYFFQGNLPQWKRFHVVESWKYQRLDWLDEFEPGQIRGDLLGEALEDSNGELFKNICAWGYPPGWVCSVDPRNSVRTRIWSQNEGAMDLENEEIFEIYGEGDSSEHLPLSASVNVPLGHTDNADDKASSTLIASDDTSDEETNKGDTHPVRWATYPNDYFSSSHLFVYTTNPSLIPSTSWDDTSFENTLDYLHQHQPKPPPPPSEEPPPLPPSPLGHPPPPSSSPLLNIISPSYIQEPKLDALSKEESDMELSDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU19</accession>
    <name>A0A9P6JU19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polynucleotide kinase 3 phosphatase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_847762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU19"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000737">
        <property type="entry name" value="Bifunctional polynucleotide phosphatase/kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="441" mass="50363" checksum="5E84AA37F5DAE6E8" modified="2023-09-13" version="1">MATQVEAGPSKKRTITETLEVEVTVEESIKIQKVHPFFAKRIDKAPATATGNFQWLPALGPTRSCFHGINLLPKASRKVAALDLDGTLIKGDLRNALVNGKPQWEWWRSFIPEKLKILHEEGYAIVIISNQALKSAALKNWKVKVENIAQAMKDIPFRIMAATQKDGFRKPMPGMYRELERIFQLEGVEIDKSQSFFIGDAAGRNYPGGKQDFSSTDRKWALNLGLRFLTPEEYFLKLPAHSNFKLHGIKVWDLPNVPRVTPTNTPLLLDPPQQEVVLFIGYPCLGKSTFYRQHFQPAGYVHINQDTLKTREKCVKAVEAAIKERKSCVIDNTNRNAVTRKYYIDACKAQKVPIRCFLFADSIELAWHNNLYRAFNLPASAAAKEPKRDLLPYTAFVTFRDNYEEPQSSEGFAEIKRVNWVFEGSEEERRSWSMWLQIDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUU2</accession>
    <name>A0A9P6JUU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_409637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUU2"/>
    <dbReference type="OrthoDB" id="2662290at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="670" mass="74612" checksum="A9ACCAAE69134291" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUV2</accession>
    <name>A0A9P6JUV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_585397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUV2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="119" mass="13622" checksum="299FB0840DEFD3F7" modified="2023-09-13" version="1">MATRIACDLPVDSSFYSILETTLSSLIHHVNIQALRIASLFAHGTCDQYLSPLLRYLGIFKMWFCCEVGGLLYLQVMASRTADARLGMHYFGIEPLSCRRLFTLFLSLYPFVMTIFYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV44</accession>
    <name>A0A9P6JV44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">beta-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_845512</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV44"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040478092" description="beta-glucosidase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="12">
        <location>
            <begin position="655"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="735" mass="78644" checksum="65EBD2C967D91216" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVH8</accession>
    <name>A0A9P6JVH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_831736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVH8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="26694" checksum="D26C1975E1A9B4D8" modified="2023-09-13" version="1">MAQMSCLVVRWINPQEPPKSTTANHLQKLTLRGNVQPTIFAWLFAPLLESLVLEFVGLSTFFSQSPSVNLPDFLNRTANPLKELHLKNADFELHDCLNAATSLEILVVENTEIKNSNYGGLEALLSKDQPGYSTRPFAVPPRMACTRLRNMHLTGIFMSQAVVLGPLVSSRLGDQASKNGVVELENVYARLLRGHHTADIEVLEKMVEGIVTKLSNSFSGESINSSNSTQCLSSEFREIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW34</accession>
    <name>A0A9P6JW34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_207783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW34"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="33883" checksum="F9A6E55AD801D426" modified="2023-09-13" version="1">MHDWNSPTELQRDIDITTKLVNIWMGLYLWEMVTSMGFERAVIKKMRVLQWQTAPYFISRYSYMIALLCYGTVMNSMSRANCSTLHAVFFFFETSIVFASTCFALRTMAIWNNRFVTRGLWTIVAGHAVLVVISTLQSRAVWNESLAACVYLDPSRAYLIVAIARVYTVVLDALILTLNVYKLRVGFMASRDKGQRGLVWVLLEQGLIYFIIAFLCNVTAVGFLIWKPNFLIGIIATTPASMFTVIVACRSVRNLSDFVAQECQGAYRLPTIATGPMEFTNSIASEGEVRNLTKIIHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW59</accession>
    <name>A0A9P6JW59_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW59"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="116" mass="12655" checksum="51D745783A4BB391" modified="2023-09-13" version="1">MSENFMFHNAFVKVTLPGKPPVTKVVFSDQTELINEAKAKQCNASFKTFITVASGGKILKYKYSGQQAFVEAPSPDYPCIIRIALTGTGIRISVPDGIPPPGQPIVYTDYPFTLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW97</accession>
    <name>A0A9P6JW97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_841634</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW97"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="254" mass="28508" checksum="5F5C52A5B1D42FCC" modified="2023-09-13" version="1">MIAVKQVELPQTASDKADSRQHMVVQALKSESETLRDLDHPNIVQYLGFEETPTNLSIFLEYVPGGSVGSCLLKHGKFEDNVTRSFTAQILGGLEYLHSKGILHRDLKAVNILVEMTGVCKISEFGISKRTDDMQGGAFTAMQGTVFWMAPEVINTQKSGYNNKIDIWSVGCVVLEMWAGVRPWDGEEILAVTSKLYHFKQPPPVPEDIVLSPEADDFRRRCFVINPDERPSAAELRRHPYLAIPPDWIFNGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWI0</accession>
    <name>A0A9P6JWI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_889072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWI0"/>
    <dbReference type="OrthoDB" id="2879353at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="119" mass="12878" checksum="F048761AEE80B71B" modified="2023-09-13" version="1">MPTSDGYIKTTSSGSRFMAVFTINDTAYTFSGPLGGSSQPWICTNASVTYNDVRKDLTSSRPFEGHVGPKKVKFQLDNEVTITGTLDMPIHPPNSVSGTGSWTSNFQIKNVRDDGVGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWL2</accession>
    <name>A0A9P6JWL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_843684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWL2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8342" checksum="B47C2DAE1D8CD890" modified="2023-09-13" version="1">MPENAPFNCALSAAVIVLSQRLVLRNMNSSCYPYALFILLHRCFRSCWEESMLTSGKSLHSVRIKLTGKLFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2W0</accession>
    <name>A0A9P6E2W0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158042">
        <property type="protein sequence ID" value="KAF9521498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2W0"/>
    <dbReference type="OrthoDB" id="3235041at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040505324" evidence="1">
        <location>
            <begin position="29"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="330" mass="37213" checksum="7D3368962B84C722" modified="2023-09-13" version="1">MSCCHHSLPLTQNKILFLLLLGCQVVKQWFHNNGRRSSAWRGLSAPRKPPVTQVLYSLYREAVKAKVKELSGGAAAGTSLWLAQFQPACQQVLDSLSPAEFDAVEAARTEWVVKAYPMEEQLRMLRKHGKKHLRNFADQVFRIFGMRICVLEYHPSPDQKDGPAFWLDIHDFTGDFETNVEKMSDWLPEYFSDIDTGWQKYVVYAQKMAQPDASPGDAVYTTKDNLSVIKKRNSAIVLDHDVAGWPTLPLPPAAPNHGIPAPEKLKDAQGLLWAFVTAHYQKASGRNSVKVPWNQLAANNREFLAMEYCPPGLMLCDPSNMGIDTIREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2X2</accession>
    <name>A0A9P6E2X2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_823523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158035">
        <property type="protein sequence ID" value="KAF9521528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2X2"/>
    <dbReference type="OrthoDB" id="6118920at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NadR/Ttd14 AAA" evidence="1">
        <location>
            <begin position="11"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="198" mass="22341" checksum="B24CFFD0E3E8B077" modified="2023-09-13" version="1">MPLLPERKISFYIIGPSSSGKTTLCEALSKRLGIHDGAFVREVARTVMKEKGYSRDTIGSLQMQKDIMEAHFVQESSLDNSGFKIRVCDRSAIDAVVYAILTANSVKVGEERQQALTESPGFQEALNRYSDQRSIVLLLKPVPGWLVDDGVRSLEEQDQCLRVFKKLLADLKLFYFEVGEEMKFIEERINFAMGLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E300</accession>
    <name>A0A9P6E300_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158023">
        <property type="protein sequence ID" value="KAF9521574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E300"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040350021" evidence="1">
        <location>
            <begin position="22"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="197" mass="21650" checksum="6E0C9C0BB44E1CBA" modified="2023-09-13" version="1">MKLTLISSLFILFLLPTATNAYCCYGGYPPNPCDKKRNVPSQSRIYPQDKSASREVANVLKERAFVCCCWAGNHNNCGEYCLLKYLSDLSESASTSAALKRASALMITSNSENGYMDLRSEVQHKPRKNTFMSQDLSRIFSTHITSLKELSIGKLSDEKGAQRAVKVFYLAPIVTSRSFSVVISVGGLGIAGLSKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E388</accession>
    <name>A0A9P6E388_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158001">
        <property type="protein sequence ID" value="KAF9521697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E388"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="278" mass="29520" checksum="248495D2814810D2" modified="2023-09-13" version="1">MARYLLSIDDSFTDTGEGNTSKISYREDYRFFMNFFINVQHKNPAWWHKLAQCWNVEVLGISEKSAKAAKQGSRTLSDTHAAQKLADELAEAVAMVQIGEPLSPTSDSESFDFSAVHNLSPGPGSPYINPDENLDTEDIEDIYGDLVEPEIAAAAAPPGPVGQSVAAPVEITPAPTPPAQENRHSSRQTVLVNSPAPAPAPATSLQDPAPAVAVSNAAPTRRATRSSQKSTTNKITSAAPVAPAARAGSSTETACRMSGQHPKLKEEALRRHSGPGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3E6</accession>
    <name>A0A9P6E3E6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157988">
        <property type="protein sequence ID" value="KAF9521798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3E6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="18766" checksum="5D1B7184D2A56657" modified="2023-09-13" version="1">MGQKLFSEDRANVSAGMPHASLQARRSGKWSLGDESLSRISLKRGHERIKKVRSEDGGSREVLLLGLRFDTAQPHARDIPVQAACSELQPAKVEAIMTEEKDEISQVPAMTFNLDLNPGLDFVHLFPQEYEGNLINRASAKLGIGSGGVGVLTMGFSAPDDANQAEYEEAETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3E9</accession>
    <name>A0A9P6E3E9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_865225</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157989">
        <property type="protein sequence ID" value="KAF9521785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3E9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="7">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="58"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9521785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="181" mass="18386" checksum="12671590417F7DAB" modified="2023-09-13" version="1">MVGCSVVDTDCLCTSAMFKTMTLACAKSECSGNLSGRVDQALKDMCVDAPPTPPSSPSPSQSPSSSGSTTASFTRSSSSTPSSTTTSAATSQTSSRSNSGGTSRTTALTSGTGPPNPSTTNTSGSRSTSFPSSISTSTSLVVETIIVPPTGLSSEAFSKEIWSTSLLMACWMGLINFVLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E412</accession>
    <name>A0A9P6E412_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157962">
        <property type="protein sequence ID" value="KAF9522090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E412"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="34713" checksum="7B221C45BF086022" modified="2023-09-13" version="1">MLNCISFGINSHNASNPIIVPWTFNTESSLRSLTLGQGSNWRRQDIGVEWSTLETFVFVGDEAVGLTFMLEMINLRSALVSFEQSDDSVENPFVRLPTLRNLVIGDDDHPEPIFGICPITSLETPALQCLHIHLEPDSTHLPLLTTMLLRSQCPLVDLVLNDLNASMGNLVELLQVVPSLRTFSFNLVGESVLTDEFVDAMNPPEVQTSTHGRCLPHISKITYTGRISFKPLQIIDMLKSRSGTSLNDQIPADKQLKDFTILCKNPDWASAAKPNIMRRFYQEIWALKSLGTTFDITYEEVVTSESDRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E456</accession>
    <name>A0A9P6E456_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_139835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E456"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="41940" checksum="3C16DB1A74077A83" modified="2023-09-13" version="1">MDLLNSTTPSSSLTQGLPNPFTPLAFIPKSEAFLFSCIIYASISCLAITTWDILNFLRPDGHIILCEKFNWRVLIFVVARFSPFCFFSSLVIFFTSDKMDCDALYRAWQSVYVLVRASTSLLFYFRVSAAYNNNRYILGFFGLTWAVAVGATIAAMVWGITNFQIGPTKYCATSMTGPHVLIASFTEFFNDTLICLAILYKLGGESWKKRMKSLRGLFRPYRKCSYITEQFVQGTLEYYLLAACLNIILIIGCLAISRLPKTYSAIPLIIGLPASTVINLLALRVYRGLKLEASTSTAQNKLGDTLVVSSIAFGAQNRNSNIQHSNISHRLQSLGSASSPAVHIQTETVGAKDDSMHPETGNDVEKGFSNRYISAEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E478</accession>
    <name>A0A9P6E478_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157956">
        <property type="protein sequence ID" value="KAF9522202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E478"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="7561" checksum="99D33CDA184E17AF" modified="2023-09-13" version="1">MFIESQKNDDCWLCINASVIFFAGRWMITTPFQFRHHGLLHNRLERRSIHERYIVSSLNGNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4D1</accession>
    <name>A0A9P6E4D1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease H</fullName>
            <ecNumber evidence="4">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_116852</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4"/>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4D1"/>
    <dbReference type="OrthoDB" id="407198at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.970.10:FF:000002">
        <property type="entry name" value="Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H1 N-terminal" evidence="11">
        <location>
            <begin position="6"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9522344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="8580" checksum="4B0548EEDE520380" modified="2023-09-13" version="1">MKKVSRYYAVRRSRVPGVYHTWHDCEEQTKGFKGSRFKSFDCQQDAEDFLHAKDSSNFITSISSALHNPLNLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4S5</accession>
    <name>A0A9P6E4S5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_899543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4S5"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="51927" checksum="9E718C0AB3F20188" modified="2023-09-13" version="1">MSNRRIIVDDTDPSINYVGTSWKADQGSHDHIGTQGPPYRSTLHGTDMSASFSFQFSGTDIAIFGSANSRNISGILDPQWECFIDQKHFGTEIESLAQYGDDNNRVFFESPSLLDKSHTLTVNVTVAHNQIFWLDSIEYTPSPTISLEYSVTRVWGEDLELRYGQGWKFEDGVFRNMTQTKDAFLEFDFIGDSITWVSWSTGDYPANTTKGSYSIDGGSPHIFNITLRRPSEIGQIVYNQKLFETPLFPRGRHNISVVYHGNAETFPLTLDYLLVQNGTAQPPKANHGPTSANGAPTSVDGALPTAKNDHASQPTKKSNSGGVVGGVVSACCVIIIIIIILIRRRRYFNNSYSISVEPFPLPSAGLAWDDPSQTANSPPAGFPAIRKFALNPGGETNLPSNGIATSLRSPAPTLPNGLINQPSFEGINEIPTHEHHLSPNGASTRVVRHEDSGVRCIQVVPQNVFELPPEYTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5B5</accession>
    <name>A0A9P6E5B5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157935">
        <property type="protein sequence ID" value="KAF9522760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5B5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="1">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="22695" checksum="C549404CA65B49B3" modified="2023-09-13" version="1">MSLEVFDEAAAYLQHLKDHCVKLVLVHYPDAIRPKELIEGQHKLTHLIIDKIEALVGPELHFHLGEVDRQGKHSNMMHPCIRQVCIDFFYKSEQGPLAHRLPKVFQGCVPEHAVAAVATCICHALEEYSFGKHFDKKFPSVSDRSIYEGILELIEMIKTNPYHKNKWDQCCQEWARDGMDTGIPRMEKRVFKVYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5E4</accession>
    <name>A0A9P6E5E4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_75132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5E4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040486062" description="Lysine-specific metallo-endopeptidase domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Lysine-specific metallo-endopeptidase" evidence="2">
        <location>
            <begin position="151"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="35078" checksum="E12B41FC05E8A241" modified="2023-09-13" version="1">MFSTRLLPLIISALGVLAAPRLHQGDRVNPFNSSTFASYRTSADQVPMTSPSILVYSGCSPVNNQILDDVRAQFVLLSRGAKKWYDAITAPGVDPAVQRDAQKMHAFWFGNFVGDPKWLRWNNILITQVYKNAVQGWNDNYNANPTPANPTASPLNFDCEPIRPGGCEADFFAYTAGGDHLVHICPHFFDAPPVNWNVLVSQEERMAAGTMAHEITHSRYLIGVFDVGGIEQPWTTDRNVGYGWDNCRNAAKTDPLNAMLNADNYKFYFQRSFYQYCQCSPYEGTRDTAPAASEKRQICGAFWAAVPKGSKCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5N9</accession>
    <name>A0A9P6E5N9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromatin modification-related protein EAF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_799912</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5N9"/>
    <dbReference type="OrthoDB" id="124855at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18983">
        <property type="entry name" value="CBD_MSL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.30">
        <property type="entry name" value="MRG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038217">
        <property type="entry name" value="MRG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026541">
        <property type="entry name" value="MRG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF15">
        <property type="entry name" value="MSL COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05712">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038133">
        <property type="entry name" value="HAT_Nua4_EAF3/MRG15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51640">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="9">
        <location>
            <begin position="25"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="80"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="36627" checksum="42B9ED733B502AB5" modified="2023-09-13" version="1">MATTTTVLPTFTSNERVLCFHGPLLYEAKVLKTKTVENPLPGQLGGPQYFVHYKGWKQTWDEWVPPTRLLKMSEENLARQKQLQLSTPGAGHGGSGTGGISKAGGSKSGAGGGSKDNQSARAGGRKDGARGTKRAREDDDSTRKPEMKLNIPEVLKARLIDDWEAVTKNNQLVEVPRSPNVKEVLAQFADHCLTTQPSTLRESKLLVQTVIDGLQTYFDRALGTCLLYRFERIQYATVRRTYYTGQHVIVGQTEKEMSEIYGAEHLLRMLVNLPQMISQTMLDSDSVNLIRDYANELMTWMIQEQDKIFQKEYTHATPEYQNLSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5W1</accession>
    <name>A0A9P6E5W1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_871796</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="3"/>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5W1"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004760">
        <property type="term" value="F:L-serine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019265">
        <property type="term" value="P:glycine biosynthetic process, by transamination of glyoxylate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000049">
        <property type="entry name" value="Alanine-glyoxylate aminotransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000027">
        <property type="entry name" value="Serine--pyruvate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF24">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="11">
        <location>
            <begin position="25"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9523065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="397" mass="42636" checksum="196DA153764D398E" modified="2023-09-13" version="1">MTSSTDFKQEPHNIPGPIEVADEVLYANAHPSMSHVSPDFIPVFGDCIRLMREVLFTKDAQPFLISGSGTLGWDQVAANLVEPGENALVLHSGYFGDSFADCLSTYGAAAEQLKAPIGGTVPLDQLASALKSKSYKVVTFTHVDTSTGVLSDAKAIAETVRSVSPNTLVVMDAVCSVASEEIRFDDWDLDVVLTASQKGLGAPPGLSILLASQRAMGVWKERAAKGVKEGSYYASWGKWLPIMKAYEEGRAAYFATPPVNLIYAFKASLDLITGKASSNLPSLEERFKLHRQASQRIKSAATALGLKQLPLKPAEAANGMTAIYFPPNVTAADLLPRLVKKGVVIAGGLHVDIKDKYFRIGHMGISVVEQSRQDVDTVIRSLGESLQEIKEAKGITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E760</accession>
    <name>A0A9P6E760_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_732463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E760"/>
    <dbReference type="OrthoDB" id="3052647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="359" mass="39996" checksum="F0FCC7F7D057DC85" modified="2023-09-13" version="1" fragment="single">TRSVMVDDSSPDFTYHGSQWFVDQGSLDLPDQGTPVYNNTLHGTTESAYFSYSFEGYLPAHLNLQGSMIDVRGTNIYRNDTGWSMVTVDCYVDNFHIGSTSSSTSNRSLNNFQWCFQEGMLETKHILEVYAAVPKNQTFWFDWLVYVPTAGASLESKIVFISKEDPNVNYVSDWRNISGYPKFTTQHGAGVIFQFIGTSLSWYGGSIPENMGNSPTTGSYSIDGHSPTVFNLKNYPQNSQNFQKFFETPTLPMGQYNLSVVFNGNNQTVPLSLDFFLVQNGTLSTNTSSSTTDIPLLPSTSPSNKQQDTPLPIKIAVIVGSIAGVLLVLAFTLWYVCRLERNRKQRRKAVEDEDGNGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7B3</accession>
    <name>A0A9P6E7B3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7B3"/>
    <dbReference type="OrthoDB" id="3265918at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="390" mass="43603" checksum="D7DC978F75E4C208" modified="2023-09-13" version="1">MQRCPELRKLPKAPKISSILWKYQNPGSAAQLIFYSRSSQPLDPTHPAANWNPRGLPQHITNGLQLRAIPVALLDTPQHSFSPFKRPFVTWNERVQKAMDAGVMGVQAGRQLNIVWKQTGQLVGNTQIYSEDDQDLLRRTRLEGRDLNPASPLFSAKLQRAKRRVPMSLFIVTSKAKMGSLRCRRKTIASRVKTALNYIVSRGAYFEQSSKSSHDNADAHKAANSSTEKKARSRPTGVKFDSSKLAPGRQLVLQGWSYIIHLTTEVYRMPYAQLIFLLRNALSTVNAKAIEMENNWLAQSLLYKQRQVSQKLKSGTELSKSGWSAPLSATSTDERAGEPDSEPRAPCTPIPPSHATKTRSTFDSAAWRRNLTSQLKLLSEAEATVAAERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7F7</accession>
    <name>A0A9P6E7F7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_898197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7F7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="227" mass="26565" checksum="E7AC7ED083243128" modified="2023-09-13" version="1">MSLIHRPNLVINLRKVEDAREDLVREAGIERLSLHLPVFHPDDIKDALLYPPIPSMFSDVAGSYTDRLLRPHEIKEIWTDKAIRLRKPQIIVEQICVGAHHRVIAEGLIDFHRTLIRGTRISARYNDLPTDEYRYFVVNTQYLTRELAIIRVGLCTCRGWRVPAADFILELPRWRCDVVFPKALAHYVNHRLDFLIPNYSHRRIEEQARQDLIEQGHGQGPLEEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7J8</accession>
    <name>A0A9P6E7J8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_820797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7J8"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01250">
        <property type="entry name" value="pro_imino_pep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040422862" evidence="3">
        <location>
            <begin position="25"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="59"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="328" mass="35886" checksum="07F5468807719281" modified="2023-09-13" version="1">MAPFIYAPVILAVYFASHFATSTSVPVVTGELDFKIPTLNTTGKTWYKIIGNLTSHQRPLVALHGGPGFDSEYMEILSNITTPRSGALVVYDQIGNGRSTHLPNKLGDDSFWTDGLFLSELDNVLSKLGIQDNYDLAGHSWGGMLAARHATSRPKGLKRLVLMSAPASIDLWVGAGNVYLKELPQNDQDIIISNEKAGTTNNTDYQKAITYYNTLHVCSIQPMPEPIAAGFAVMSSDPTVRRSMYGPLNFQVTGSLKGWTIIHDAHKISVPTLVTHGKRDQANQTAVEPLLKEIPNVQGVEFENSGHMAHFEEAAKFTRVVSKFLSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7M8</accession>
    <name>A0A9P6E7M8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7M8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="80" mass="8527" checksum="376208F8AD86448B" modified="2023-09-13" version="1" fragment="single">MCSNKAEIPSPQLSAQPSIQVSFKFQVTMQFKLFTGILFATWAAVVLSAPAPAPVAVPEESTELDKNFTGAWSGGGGRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7P0</accession>
    <name>A0A9P6E7P0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7P0"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36504" checksum="29D0BE458A5EF6EF" modified="2023-09-13" version="1">MVDWKSPVVAKAALEAFIKLAHVFTGIYIWELVTSMTLEWEFITRKREFKWPLAFYFLNRYSMFAALIATIITFDGNPSNCRAAMSALLFFAHMALALASANLAIRTTAIWAGNNAVILILTLLMCVHSGLVIFQAATAHVQFFPGIGCAPSSINYAWDVAIYAFALAFDFFVLSLNVWKLRSHLHSKSASLLTTFVFKQGIAYFLAACLVDLVAIIFLVLDLNIGTIAISTQFAALVCTIVACRAVRSLSGLYKDGNSEMTNMATANAPGRRTTTISSVSKGPTFDLVGTRGDINGQVLVEMETVIRRDSYTHDRDSDSKKQSDFNDSLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8A4</accession>
    <name>A0A9P6E8A4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_898140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8A4"/>
    <dbReference type="OrthoDB" id="3251431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="776"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="825" mass="92064" checksum="5E46803A23CE15D4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8R8</accession>
    <name>A0A9P6E8R8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_909857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8R8"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="55097" checksum="4FE18F5E56A747A0" modified="2023-09-13" version="1">MASDDGQSTLASLFDTFPPEVIADIFWHSLPVWSLETPCPLSDGPNNEFSVFDIGAVCQSWRKLAWSAPILWSAVRVCVDVDRAAMQTILLDQWLSRSGSLPLDVCLTLSKDVPTWTPGSEPDSAVVQLVAVAGKYANRWRSFVYEIPRLFHKALPPRHTPLPLLRFLKIDPLYNDSRRQNPIFLQAPLQYIALNGIHIEWLQVSFDKVMELRLSEFYLDECLFVLSQCLMVAHIVLEDVTFDYSEDPFKFDYSKLPIHLPSLRCLELRGRIKPLDIVTENLIELTYSGLNSHGIPLLCSLLPPILNLHRVCLLDCDVEPPEMLGVLEELQTVRSFEISAYHSRYVVHQVLDEDLVGRLRRSLEKSVLLLPNMEEFVYRGPRSFTWDSLITAWKEVALGYEEGSVESVVVQRLRWDLTFTLPGRDIPQNGSQRRRELDRLQIQSNGRLTLRFPDQENYAPSKILPTTEPDVLPALPFNEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E990</accession>
    <name>A0A9P6E990_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_568613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E990"/>
    <dbReference type="OrthoDB" id="2903551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="261" mass="28693" checksum="DC9A8893DA56505A" modified="2023-09-13" version="1">MSRGLAHHQPPPPSTPAKVAPVYRDDERDMLESLKGLSIKNFHDWYFILPSFFPTILMRCSSNDNGMGCNTPSSNNTSLPTPPALRSSQVYLVTEEQPMLSSNWCPPPNAPLLKDVDSFTDFTGHSSFDFPLPNNAGADDAPATKLPLLFHHPENVDDALDIDSDLISPSETVYPNSLALDLLPCTEDPALSVLAWIEGVSATQEEQTTPKKRRRSLTASSEVEARRVRAWTPTVEPSHAPQPSPRRGGCPTERQEPEAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9C0</accession>
    <name>A0A9P6E9C0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF8040 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_752081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9C0"/>
    <dbReference type="OrthoDB" id="2430314at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058353">
        <property type="entry name" value="DUF8040"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26138">
        <property type="entry name" value="DUF8040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8040" evidence="1">
        <location>
            <begin position="26"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="88" mass="9586" checksum="566DCA36CEC2CC40" modified="2023-09-13" version="1" fragment="single">ASFVHLIGIAAVLYSQPGYFSQPYHTSALTGAAWVNELIHGHPDCIFCQLGMHLHVFISFCAALELLGGITISRHGITVEEQAAIFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9P5</accession>
    <name>A0A9P6E9P5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane amino acid transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_818696</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9P5"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="44"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="478" mass="52138" checksum="5D675C87628D959A" modified="2023-09-13" version="1">MVQTYGTVTQQQSHLDHEVDPSVADESSTLLGGPVTKALPDGHATIFSSISNLLNTIVGSGMLTFPLAFASAGIVPGMLTCVFSGAVASFGLYLLSLCATKTSHRRASFHAVSQLTFPGAAIFFDAAIAVKCFGVSISYLIIIKALMPNVVASIFHDLTSPDTNPPDWALNGRVWLMLFMLILAPLSFLRHLNNLRHTSYIALFSIAYLIIIVITCYFWPLKGMPSSGEVRWIHFTPGFVSTFPVQVFAFTCSQNLFPIYNELKSNTQGRMNTIIGGSIGTATLTYLIIAVFGYLTFGSQVEANIIAMYPSTSLFIAIGQLAIVILVMFSYPLQVHPCRHCLDKVFHPEHLAEAIKATEAEAENDEVELGGDEHGHHQGLSPFKHFVFTTCIVATGFLTAYFVNDLQLVLSFVGATGSTSISFILPGLFFWKLTKNDPNTSKTMNWSALALMIYGMCVCVFCLSFNVYGLFQGKPTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAQ6</accession>
    <name>A0A9P6EAQ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_859311</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAQ6"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000040">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="134"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="332"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="360"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="457" mass="49903" checksum="3895DB57EC76E6D1" modified="2023-09-13" version="1">MAMATPIRKKRNFKALQLSVADSTAPPATAGAAEPVAIRQAPAPIAPAATAPVGGKKRPPPMVIKAPKIPNHNGSVSAVEQDGTLLTVTNVQAPHSASPVVGVRRNTYHATLSTTLANLDMNAEIKFDLKDEDLKDLRELGQGNGGSVKMVEHVPTKTIMAKKNVLIDAKPSVRKQILRELQIMHDCHSKYIISFWGAYLADPNICICMEYMDKGSLDGIYKKIGPIDVDVVAQVALAVLEGLTYLYDVHRIIHRDIKPSNILCNSRGEIKICDFGVSGELINSIADTFVGTSTYMSPERIQGAQYTVKSDVWSLGISLIELALGRFPFAESTSDDEDDSDYENTLSPARPGSIDLSKLPPRKPKTSKKDKRRSKGVSLQGGGMTMSILELLQHIVNEPAPRLTPEGRFPPEADEFIDACLLKDPDTRKTPKDLLKFPWIELAHLSTINLEDWASTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAX1</accession>
    <name>A0A9P6EAX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_502463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9525998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAX1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="10505" checksum="06C65808BAC1CF9F" modified="2023-09-13" version="1">MLRSGKLQWVVLLDRIYITTVLVVYSQCQYIYVSFIICVPKLLNPIQKWKNKQILYIAKRLLGLCQHADHLKSSCEFTFVPWHLEPACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB20</accession>
    <name>A0A9P6EB20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_817715</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RFT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB20"/>
    <dbReference type="OrthoDB" id="9979195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034203">
        <property type="term" value="P:glycolipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007594">
        <property type="entry name" value="RFT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117:SF5">
        <property type="entry name" value="PROTEIN RFT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04506">
        <property type="entry name" value="Rft-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9526073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="546" mass="59779" checksum="50AF0087FED6FF2B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBB8</accession>
    <name>A0A9P6EBB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_746222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBB8"/>
    <dbReference type="OrthoDB" id="2802795at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="100" mass="11224" checksum="22CEC4DAB21E0223" modified="2023-09-13" version="1" fragment="single">RMKGCLKLKSRSPSPGHTDEGLHCRKCVAFGIQITEEVHFADEWDRTPTEPTRKLTYQDLLELKEIQRSLPHADQPGDPLTGKPAKHYLSAVPIGLLPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBN6</accession>
    <name>A0A9P6EBN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBN6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="57" mass="6714" checksum="3FF0BFC64624F950" modified="2023-09-13" version="1" fragment="single">MISRKKRGQPGYRFLIHRYEFTPSSWHFQVLDSVCVCLMGSQINGRGSRLSHWITMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBP0</accession>
    <name>A0A9P6EBP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_770191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBP0"/>
    <dbReference type="OrthoDB" id="3259646at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.660">
        <property type="entry name" value="IL-4 antagonist (De novo design) like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="309" mass="34674" checksum="B25C28F4E3D90DD9" modified="2023-09-13" version="1">MPGYLNNLGLSFFERFEQMDNPSDIAAAIGHQEKAVMLSSEGDPNLPLHLHNLGHSFFSRFQQTHDLTDIATAIGHQEKAVKLTAKGDSDMPGYFNNLGVLFFQYFQQTHNLAHIITAIQHQEKAVRLTTEDSSNIVVRLYNLGLSLSVRFKQTHDFTDIIAAIRHQENAVKLTAEGDSDMPACLSNLGASFYKCFQQTHNLTDIAAAIKHQEKAVKLTSEGDPDLPQYLYNLGISFYIRFKQTHNFTDLTAAIRHQEKAVTLTSNGHSNKHLYLCNLTDCLSLSYELTGDQAHKSTAEKYKEQLKCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBX6</accession>
    <name>A0A9P6EBX6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_502243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBX6"/>
    <dbReference type="OrthoDB" id="2938299at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="164"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="62972" checksum="75772D0A09B1AB22" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEE1</accession>
    <name>A0A9P6EEE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D123-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_768409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEE1"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="364" mass="41832" checksum="DF11995BCF16738B" modified="2023-09-13" version="1">MPSADAFSIFPSISPSYVLLFQFSSWYSIFSRHSINSTIIRPLSVEFREYLDADSVFVPEGSENTPVESSLSDDEDNLGNDDSDDDSEQKQYAFPELDQRIRDCITKYEAVFPKLNFSSPKDASWILPSSSPLKCTSPADVYMLLKSSDFVSHDLDENRVFEGCGYESNDASDYELELVLRKWYSVDRGREIRCFVRSNLLLGISQRDTNYYEFWNHEETQEKIVSAVRLFWEQNIKSRWVGQTDYTFDFLFTRDLSKGHILDFNPYMPKTDPLLFTYDDLRDLFQAAQLAHDTESTLPLIRPTLRVVDSPTHPLAAKNAPAHQHNMIPYEAAHLSDGRNIEEFADLWKQSVKGSVRSPSDIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEX3</accession>
    <name>A0A9P6EEX3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_387415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEX3"/>
    <dbReference type="OrthoDB" id="3067737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040349690" description="Lysine-specific metallo-endopeptidase domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34119" checksum="EF58EF9D59D8E562" modified="2023-09-13" version="1">MFPLYRIAVVLALVQVALSVPLKIAYDRDASGAATKANKDRLDAATTLANSQIVNMRKGLDKAKAGDAKAKVLYEATFGKAGANSDINKVDQTVKALETGTMTAKVAAHPFRNGEIAAVPWSQNKKTDPWVAGPVRFSKQFHGDGDKPLDANGRAGTIIHEATHQLKGTGDDVHKTNGKIIPVSGEAKDAHATLTGYTSAHNMHKTVAEVKKDKAFTGVRDKATNMHENAESYALFASLCSQPGVLRRRDIHPFNRALVEGDDEQLEYLARRNSCKLPPNHIAKKAAAKKAEAAKKSAKSPVIAKKSQANGKVLLRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF55</accession>
    <name>A0A9P6EF55_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipid droplet-associated perilipin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF55"/>
    <dbReference type="OrthoDB" id="376826at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58113">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="362" mass="39088" checksum="462882079EAB0F96" modified="2023-09-13" version="1">MSTTATETKPAGEQHAPEITVISRMGSIPLISSSLVTLNDALVNNAYTRSPYAHAKTLSSTAYRLSEPIQCKLAPLILRVDGLANNLVDAVQSRYPYPFEAQPEEVATYVRETKDNTINGVNKAIDDRVKTPALHVAQGIDQRFTPLVNYFETAVNRFNNSDEGPSNPPDATYQYQRALALTSRLGGTVYVYSNEQLKQIQAQSVLVQKAQETAGSITAVASSSLASAQAHIHGLSDNMIAELQKIQASTSQLAASFQANVHDSAAQIQSSLPQIQQSFAELAQAVGETTHHLKDIVVQKDLPIQEKVSRVSKEVQDRIAPLLDTIKNGLSEALAKSKETKDSATNGNSNGHAENGHVSESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF84</accession>
    <name>A0A9P6EF84_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF84"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36186" checksum="3E93C208F4DA3791" modified="2023-09-13" version="1">MVDWNSPTVINATAQTSKYVGHIAFGIYLYDYIASLWFEYDFLRGKKKFKWPLVFYFANRYSMLGYLIASVTVYNFPSNYRINCRVVYGLLMSFGEVSRGLASVNFALRTIAVWSKNRFVIAGLSVAILGECAIVIIGIRSTTSTFIDGFGCVPHLEEATLYWLTVLFIYSACFDLTILVLNVSKLGLPIGRAFKLPNSLVTLIINQGIMYYFVSLTCDLIAVTVLLLDLNFVMAFMAVPADLLSTMVACRAVRSLTNRAYENQTEGQYMPSALFFAEPHSRPHTHGNTTTSPYRHNQIGIEMKTTVSPQNDSKELYREEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHF1</accession>
    <name>A0A9P6EHF1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_853555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHF1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040299285" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="7597" checksum="D21252F100F68BE3" modified="2023-09-13" version="1">MIANLTALTSAAQLHFVIALSVNAYQLGHITAASIPRKSIASSSEIVRKDETPSAHFHGRETVCSGTGFGAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHV7</accession>
    <name>A0A9P6EHV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_875631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHV7"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040231037" evidence="3">
        <location>
            <begin position="21"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="390" mass="42724" checksum="7EE684585B0E3519" modified="2023-09-13" version="1">MRFSYLLVVVVHLLLSFSSATLFEKRTSASYDGQADALAAQGLKNLVDYTASHGFPSQKCNLTTAAVRREWGALSIDERKNYTAAVNCLAKKAARTPSSVASGARNRYDDFVVTHIIQTPSVHGTGNFLAWHRYFVWAYEQALRNECGYTGYQPYWNWGKYVDDPISSPIFDGSDASMSGNGVHVAHETTCVAPGFCLPAGNGGGCISSGPFKDFKVNLGPVFGAYSDVKPNPQSSGLGYNPRCIRRDISAYAAKSVTDAITVDLIKNNPDPYWFITNMQGDFPRNYLGIHAGGHAIFTGDPGGDIFVSLGDPVFWLHHSMIDRVWWTWQNLDIPNRQYSISGGTSMFDFQHTSPNATLDDAIDLGVNGDPITNRDAMSTIAGPFCYIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHW7</accession>
    <name>A0A9P6EHW7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetolactate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_852985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHW7"/>
    <dbReference type="OrthoDB" id="2013116at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009082">
        <property type="term" value="P:branched-chain amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000001">
        <property type="entry name" value="Acetolactate synthase, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="entry name" value="ACT-like. Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054480">
        <property type="entry name" value="AHAS_small-like_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053050">
        <property type="entry name" value="ALS_regulatory_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31242">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31242:SF2">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22629">
        <property type="entry name" value="ACT_AHAS_ss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="100"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="22"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="37048" checksum="32073B0194F11B50" modified="2023-09-13" version="1">MATVFLLRSRLPHTIVGRRLLSSSNIRRQDSNPKDLAKPPQPPKPIDDSTSALDYKRSQRTRPPPLPAMDIARTRSAEEAVTNILYNTPPPSLQPFKKHILNCLVQNEPGVLSRVSGILAGRGFNIESLVVCKTEIRDLSRMCLVLKGQDGVVEQARRQLEDLVPVWAVLDYTDTKIISRELALVKVSILGPEYVEEQLLGGPTHQPRRENSPADSKLHQETVLAQNFERSAHSDASAPITPSQALRLKHQHLHSISVLANQFGAKIVDVSEHSVIVELTAKTARVEAFVNLLKPFGILEAARTGLMAMPRTPINAQDNEVAQTANEGVDASLLPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIB1</accession>
    <name>A0A9P6EIB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_260593</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIB1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="168"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="616" mass="70270" checksum="09EF8EA2F9437878" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIE3</accession>
    <name>A0A9P6EIE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADF-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_851237</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIE3"/>
    <dbReference type="OrthoDB" id="20822at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="143" mass="16007" checksum="E18A3E506AAECCB8" modified="2023-09-13" version="1">MADCTDPAINDAYQEVRKNSNINWLLLDYEDERSDKLLLTATGNGGLSELKERLDEGKASYAYVKVTYANDKESTREKFILVIWIGSSCKVMRKAKISVHSADVKSVLRVYSIEVAARDKDDLREDPIVSRLRKAGGASYDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIH4</accession>
    <name>A0A9P6EIH4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_852335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIH4"/>
    <dbReference type="OrthoDB" id="5289249at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="29"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="24796" checksum="E2ACC5F5EAF7C521" modified="2023-09-13" version="1">MSRQDGSSIDITPTTTPTSFAPSGIRPTNFTRIHRPEHEISGTFVIDRGLRLPCPDGSYNLHLATTKNLTANVYILPPSSSATQEDKGTATSLVFSGVNVSVEIHRSGSVGDDYPLNIQIRFEKAATISLPRSFNGPLQLCTSGNFITFHRDLEPNFLLFSEVDGKTNGFIGEIDYSQLEDFDNVAGDKINTLSWGSEQRRITLRYDDDKLKTQSRSTRVRMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ64</accession>
    <name>A0A9P6EJ64_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ64"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="8061" checksum="C08DC140D9DB3D85" modified="2023-09-13" version="1">MAPARTGAQKAHISHLAARLAAPKHQLGDEAARSTTPRPTTRKIAEWQLEAITLHSTQLEVDLIERTNRVTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJA1</accession>
    <name>A0A9P6EJA1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_851981</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJA1"/>
    <dbReference type="OrthoDB" id="2105912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17324">
        <property type="entry name" value="MFS_NepI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910">
        <property type="entry name" value="TRANSPORTER SCO4007-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="366"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="76"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9529689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="512" mass="55403" checksum="6849FE4F5AE2A49C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJY3</accession>
    <name>A0A9P6EJY3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_851452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJY3"/>
    <dbReference type="OrthoDB" id="10262653at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="126" mass="14039" checksum="5EC049A8DE045B8E" modified="2023-09-13" version="1">MTKKRRNGGRNKKGRGHVKFMRCSNCSRCVGKDKAIKRFTVRNMVESAAVRDISDASVYPEYVIPKLYIKIAYCVSCAIHSHVVRVRSREGRRNRAPPPRIRWNAGKKVNPAVTAAEGEKGGGAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK96</accession>
    <name>A0A9P6EK96_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Calcium uniporter protein, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_850623</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Highly selective calcium channel localized to the inner mitochondrial membrane, which mediates calcium uptake into the mitochondrial matrix. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates ATP production, cytoplasmic calcium signals and activation of cell death pathways. Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer, assembles in a dimer or dimers configuration with two interfaces.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCU (TC 1.A.77) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK96"/>
    <dbReference type="OrthoDB" id="278338at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990246">
        <property type="term" value="C:uniplex complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015292">
        <property type="term" value="F:uniporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036444">
        <property type="term" value="P:calcium import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051560">
        <property type="term" value="P:mitochondrial calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006769">
        <property type="entry name" value="MCU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039055">
        <property type="entry name" value="MCU_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462:SF10">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04678">
        <property type="entry name" value="MCU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium uniporter protein C-terminal" evidence="20">
        <location>
            <begin position="233"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="378"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="410"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9530610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="445" mass="49761" checksum="A43750841CC80A5E" modified="2023-09-13" version="1">MLRAGLGTFAVANFRLLAATSSTQLHLRTLWATRAYSTDTKGQLNATHSQFLAEAPARADWNKNSPNGNAAYLKEQEDELEGVTETRGKISPTSSHLFKLILPLGSLKKNFEARDGAAPKTPPTVVLLHPSQPLSHVARLIMASLAPSTPTISFRSMSRGGQAFQWSDSTDVGDFIRDAAKSAEFTICFQYPADKSQKEYLPAADQAEERMIPVAASSDHGIDEKLLAVTVPTFADRTRFMRRRLKLVETRLEEMEGLKIQCDKEAHRGVKRMAMAGFGMLVVYWGTVARLTFWDYGWDFMEPVTYLSGLSTVILGYLWFLYQGREVSYTSILARSISARREALYKARGFDIERWIDFVGEKKTLKAEISRIARDYEGDEDKAPKDEKKKDEKVEKDNSGSNSDSALPPTEEKSPTSKVVEEETLKAIKEGKLGNEESKDQDSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKE1</accession>
    <name>A0A9P6EKE1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_904510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKE1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9531386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="812" mass="91993" checksum="CF8A12EFC3988818" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKH7</accession>
    <name>A0A9P6EKH7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_875031</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKH7"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="827"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="449"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="781"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1181"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="781"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="797"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1183"/>
            <end position="1198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9530579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1275" mass="136874" checksum="CE2031DB2FDFDA6D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKZ0</accession>
    <name>A0A9P6EKZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nudix hydrolase 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_904647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKZ0"/>
    <dbReference type="OrthoDB" id="10261522at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044715">
        <property type="term" value="F:8-oxo-dGDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000019">
        <property type="entry name" value="Thiamin pyrophosphokinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="182"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="42357" checksum="AAC557E801EF2722" modified="2023-09-13" version="1">MASPQHNLTFFDLVNLCDNVHLQRDQRGLFDLAFNNENLVPFYLTESTESPIIGLLRPDILESLKQENVRSQKNSSSVLWNLRLEDSEQSTLRQGFNGPWVSFRDWVDTPAKRTSALKELCERWRDTGLFPDVCGPTKWRSEMYPIYADPFGAHDYPSAEGRGNNLNYVFEMERSACALFGVVTYGVHMSVYDEKIEEDGLDSLHVWVPTRSFTKQTWPGYLDNTVAGGIPSGMSMHESMVKECMEEASLDPDLVRKYMRAVGSISYFIRTAAGWLQPEIEYVYDIRIPHDIDAQLFTPRPMDGEVESFEQVPHSKLLEQLRAGLFKPNCGLVIIDLFIRLGYITPDNEPDFMRIITKIHGRFDYEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL95</accession>
    <name>A0A9P6EL95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL95"/>
    <dbReference type="OrthoDB" id="3041043at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="435" mass="50494" checksum="79E42F04E968F245" modified="2023-09-13" version="1">MSSDDGSLDDNAQLLCIGNVGFGREKRVNITKFPFWEYPYNPCPKAYKRRASNIDNFLTKYFTPAEVAHFRYLQSRTQAIISGSMALQFFERIEYPNSDLDIYVENDHKKEIIAWLLQIGYLFESRRNKTLAEEMQLPPPPKDDTIADASGYFGQGVTNVFNFSKDDPERRIQLITSYISPLRVIINFHSTTFNHHLSVKHSTAGGNQDVACQKYADRGWIMTDYLITIEIEDSESEFSDKPRHVGDGFCWQIDILPKLALPEAFAEINSWLFYCGDKHPSMVSWYIYTNGLDFKYIIGEHEIYDFFNNSFGHSYDTYDGPRMAEQKLEKYFARIEQYKFEMQTAETQDNVKPEIVVPSILEFIKRPGLRVLNHNWLTSVFGGYNFLLHLSKQNFPAGLGWTTSDQKLSPMVVPLRWPIRLDFMSYGNIERVYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM09</accession>
    <name>A0A9P6EM09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_849268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM09"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="100"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="31907" checksum="90FA6C43A61B03C4" modified="2023-09-13" version="1">MAYVQVEPDDQRLEEGPEGLQFKSFLGADANASQPNNPLRSAGVGNANRSYLAEENRTKGGGGFWTVEYYQPYFDVDTKTVLKRCYTTLNPMAAPTYLSTHLNPADLYGPFWTLTTLIFALFLSSSLGASIAKYLSTQDKPYDYDFQLLSIAMSLVYAYGIALPVVLWLALRYLGVGEWSVVEAISVWGYAQFIWIPVSVLCVIPVPIVRWALVGSAFGLSGWFLAANIYPILATAEAKATRLLIILLALIHLGIAITFKVLFFSYYVVDKIGMDIDLPGGDAGTGTNPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMA4</accession>
    <name>A0A9P6EMA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_786936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMA4"/>
    <dbReference type="OrthoDB" id="2898509at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36583" checksum="E13530F160DA389B" modified="2023-09-13" version="1">MPSLPQALAANESHFAVRGSDIPVAIFVGGTSGIGEAMVAAFGRYTKGNAHVIVIGRNKEAGERILSSIPKPRDSSCIPERVFIYCDVSLMRNVVATANELKAKFTKVNYLILSTGLLNMDERTETVEGLEMRLSVSYYSRWLFIRELTGLVEEGIAKDGAGKGVVLSILAPGYGGELDPDDWEIKSDYSPGKLLSTAVTYNDLMVEAWADRRPTVPFVHAHPGLVRTPIFFRSPSYLLKLTGALLVTFARFMTISPEESAEWMWYTIDLTHTRTLEGVKTGKSPGGSWRTDPFGADKAKNDKYFGSADKRNGLWKHTEEAILRSLNAEIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMB8</accession>
    <name>A0A9P6EMB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMB8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="90" mass="10127" checksum="1FEB8558FD158122" modified="2023-09-13" version="1">MYEFSLFLVLRAIRRTLSSLPSFLCLAISHRASNNRNLSPEGSSREGSKRLAVFLPTPEPQQRVADKSQHVFDDYDMPFLVASNSSLLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMC4</accession>
    <name>A0A9P6EMC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phophatidylserine decarboxylase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_904338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMC4"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022237">
        <property type="entry name" value="PsiD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF9">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_7G01730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12588">
        <property type="entry name" value="PSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-tryptophan decarboxylase PsiD-like" evidence="3">
        <location>
            <begin position="61"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="473" mass="52907" checksum="D3B2D201E7602FDE" modified="2023-09-13" version="1">MSAFFLAILSRTLSPIDQPLQAMPESRGVGLWLPAPPDFIARWFTTINTSRLRRDTDSVLPVIQEFKQLIENDTTLFMYFTSMFDEIPSYSPYDKDVIGNPQIRDYQHMLQSFNEVIQTLPPWNDAANNIGFCGFPINAILNWPMGTPSGRSAFLDPRVNAMLKKMLTVWAGYLVSPASTNVLNTNSDGWLSPNAVRALTTSANLAGHEEIKFHDLYACDPSKPCLVYTYWDNFFTRTFKDGIRPISSPNDDSILVSPCEAAPYRLANDVSERATFWIKAQPYSLNDMLANDELVSRFVDGTVYQAFLSSLSYHRWHSPISGTVVKAYNIPGAYYSETLLNSFAGEGADPEATMRSRAYITAVATRAVIFIPADNDDIGLVCVLFVGMAEVSSCEINVYAGQHLVKGQEIGMFHFGGSTFCLIFQKDIDLCWEEDCLPPYPENMPNIAVRRKLATIRGVGHPRAENKEQVQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMD5</accession>
    <name>A0A9P6EMD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_808913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="1"/>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMD5"/>
    <dbReference type="OrthoDB" id="17102at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004105">
        <property type="term" value="F:choline-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="3">
        <location>
            <begin position="84"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="29095" checksum="58CDD7530552712F" modified="2023-09-13" version="1">MDNATAFSDDEDYDVISNPGHDGELTPEEILLGRGTTTSRELPAFEDAQDRFETTRWKASEVEAYVKKQLETTQLFDKKRVKVYVDGTFDTFGVGQALQLRQAKLAFPYVHLIVGVFSDDTLHQNNCASTYPEVERAELVRHCRWVDEVIKDAPWAVNIDFLNQRRIDFVAIDEGSSVDPTCDKARLRGYDELKKRGKIIKTRRTLGLTSQHRPSMFNLQSESQRATPTLPHTSPVATRVSELKPDIDVFGIGIGCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN03</accession>
    <name>A0A9P6EN03_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN03"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="72" mass="7913" checksum="0483E3A89C92C9F1" modified="2023-09-13" version="1">MLEALNGALSRKRISFASKIRRHSFSSIPVAFDSSGIFMPYGPMSSNALTTRGSILTKASSTIPFHISRHSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN76</accession>
    <name>A0A9P6EN76_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_588332</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN76"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000038">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000011">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="1"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="612"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="712" mass="79892" checksum="265C6F1883CB69F2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6END6</accession>
    <name>A0A9P6END6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Brix-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_759675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6END6"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000009">
        <property type="entry name" value="Ribosome biogenesis protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="19"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="276" mass="31412" checksum="119662AF4F47632F" modified="2023-09-13" version="1">MEVDEDEVVPTVKKLKNKQRVLLLSSRGITHRMRHLMNDLEALLPHVKKDSKLDSKSQLNLLPELADLNNCNNTLYFEARRHEDLYLWAAKTPNGPSIKMHVQNVHTMDELKMTGNCLKGSRGLLSFDAAFEDTEWGRLVKELFTQMFGVPSTARKTKPFIDHILTFSIVDSKIWFRNFQILENDPSQPNGPPQTSLVEIGPRFVLTPIRIFEGAFGGATVFSNPEFISPAATRMALKREKGGKYNQRKDAEADTQRRKDSRRLEEDALGVSKVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENG6</accession>
    <name>A0A9P6ENG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENG6"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="40494" checksum="A93AF6FA9295DD54" modified="2023-09-13" version="1">MSSTTPATTYDPSSILGVREYLRNSPYDCTDIEELSGGTANYVFRLKLIQPFEGRETLVLKHAKPFVKDHKDFAFGLDRQKYEVAALRQVRAWLPVDSIVTVPEVHRFDEEAHAIIMDDAGAGSLPLKEFMQKGKVTTTSAAQIGAALGLFLGELHKWGKGNETACEAVRENQQAKNISSYIFYGRMRQTLTGAQVPLLSEPPLGIEESDLQVLDEIAKETQQTMLAASDEFIMGDFWPGNIMISLDGTGDLRQIFILDWELVKTGLPSADIGQFSAEIHLLRRFHPDACGETSTILLKSFLQEYKRVGKPTDEIMRRATVQVGAHLIDLTARVKWGEKELTRTVVREGVRMLVDGSDVLEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENY6</accession>
    <name>A0A9P6ENY6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zinc-ribbon 15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENY6"/>
    <dbReference type="OrthoDB" id="5545479at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031493">
        <property type="entry name" value="Zinc_ribbon_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28139:SF1">
        <property type="entry name" value="UPF0768 PROTEIN YBL029C-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17032">
        <property type="entry name" value="Zn_ribbon_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc-ribbon 15" evidence="1">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="110" mass="12877" checksum="CAD966CB1F143A98" modified="2023-09-13" version="1">MDFCFFIPILFGCQTEIKPEGDMSIRVCPRCNNGAVTSARSKQYFEICFVPVVPMSRKHIWICSICQWSHPRQDGSWEPMTVQHPGYYPPQPPPQAYWQAEQQQQQQYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP78</accession>
    <name>A0A9P6EP78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ClpP/crotonase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_846997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP78"/>
    <dbReference type="OrthoDB" id="1696280at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF75">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="30208" checksum="EB1E6FE0CCBDC3EB" modified="2023-09-13" version="1">MSKADLLPSNNPQIALKRPKPGLWIIELQNGVDNRLTDVLVTKGMMPALDIVEKEWRQRKQAAVKNKDRAGAGGALIIVGKMDQDKFFSNGLDFANSSKDPNFFQLTFDPMLKRLLVFPIPTIAAINGHCYAGGLMLSLACDYRVMTDGTSRNAWLCMNEVHFGAPWPHSFAAILRAKIGDHRLQRKIAIEGHKFTPQEALQDGILDYIVKGKTAEILAKAEELADKFGGTAAPGVWGLIKLNLYADVLQTMRTEYRLVTVDMDERAARSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPE4</accession>
    <name>A0A9P6EPE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPE4"/>
    <dbReference type="OrthoDB" id="14339at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="426" mass="46292" checksum="E3A38F826524B1D4" modified="2023-09-13" version="1">MSHFSAEQAQRPTMRRKSSAQNLLSSFKGGNPTAVPPPLNLTTQANANSTTLSFAAAVTPTAATTPIPRDNWDAQSVHAESLAPSLGGATSPQLGQGTSVEYLRDLVQKRIITLTYVRSIHEGRSHWFHTILISQTELQKVFNNNAMKKRTYRFAILGLSLSSLLDINQPQDLLRGLLNTVTEYDQAKEEGDNKSSKMRIKFKGRNPKKGSMGEYYSESSGDASYMMTPSMPFPLDYHQTLLSLLDVLSEVYHKISKLLGPSPFSHSSQHMMGPLGLLSPQPGISYLFSEQQSLNGAAALGNPTHGHSNPNLHQPHQPPPSFSLQGVDGDTSTAMSGGLWSIANPASAHGMQGMGSTPPVPIWSPLLGEMVLKIDGKLKKISTTLLKDLDTFARNGIRDELASLDPLLRNLGDAGSNKIMYEFEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPE6</accession>
    <name>A0A9P6EPE6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_480564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPE6"/>
    <dbReference type="OrthoDB" id="3354175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="29987" checksum="351753F7289943F5" modified="2023-09-13" version="1">MPDALRIDQANLVALWVEAILYGAFLILFGASIYVLLFLKRASWLNKMMALVSVLMFALITAHIVCDVVRAMRAFTQSSNAMDFYGDIAEPSEWAKTIIYTLLSLLGDAMVVFRCWIVWGGNPLVMVIPCTLLLLSVAMAALVCQAISALTPAQEIFTEDLARWLLPFFALTFVTNNLCTLLIAGRICWTTRQTQQYTSGDSRLWRVIVMLIESAALYSIALIAMIGTFVAGSNAQYITIDALCPIIGIAVRLFEIQDFEQPLILIFIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPF6</accession>
    <name>A0A9P6EPF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Single hybrid motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845476</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPF6"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF82">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE COMPLEX PROTEIN X COMPONENT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="29171" checksum="2BC66D88A2503522" modified="2023-09-13" version="1">MPAMSPTMTEGGIASWKKKEGESFVQGDVLLEIETDKATIDVEAQEDGIVGKIFAPDGTKGVPVGKLIAILAEEGDDISNLEMPKDEPTPPPSKSEEPQGSSSSASSSAPSAESESSSSHSHVLPEHDRPLFPSVHRLLLEHGITSLDKIKGTGVRGMITKGDVLTHLGKASGPLGTFKFGPSPIEEALASKGKGAGAKGGAAAPPKTPLDGPSIRRLVVSSMLQASQKSLNPVPAAIKQADFDSIIADYLPPSPKSLPPTTLINATASTPKKSVSYLDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQL2</accession>
    <name>A0A9P6EQL2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_481419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQL2"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="501" mass="56580" checksum="939F3E128B5219EB" modified="2023-09-13" version="1">MNNPHNLLSSAPQANPTFPQEIFDQIVDALGDIESQNFIEEIRDDGISESEVLVSYQDTSGLLACSLVSRSFSDRARQHLFQRVEMITLDSERDVDAWLETFHELLGWRPRRIPDGDQLCGIRPYIKEFAASDTNGSEASMEVVTQDFLAEVLWALNDGVYGLEELDLGIELKWATLTHGLQHAIMALIQSKQLKILKLYGFIDLPSTIFLNSAFKHLRAIECFTNLALNSAVDPALLDSIHTYPALESLETDFSLTATHFASCTDNGRPDAVPSSSPLKGLRRLSIWLIDDRVFRSEDAALLLSSAAHTLQRLELRYYPVPRVGLPIFQPPLHSFSQLRCLQLYHCEGVSRKGPLVFPQPFITLLLSESTIFPQSLERLEIFLAHPYIYSDMEDIITPFDNIGEAEIIKMVDRKLSYLLLQSNVQALTLRIRLHPSVLTYVVGDVDGFVTDGCTKLKALFSATSEENILCLNIEFSEDFDYYYSRNLEVFVPEEHPMADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQT2</accession>
    <name>A0A9P6EQT2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_845257</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQT2"/>
    <dbReference type="OrthoDB" id="9978460at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16909" checksum="B660AC1E84B2216F" modified="2023-09-13" version="1">MSSTALRRIQKELREIQNNPIHNLSVTTPDDNLFEWKCTIKADSDSPYKGGTYNFNLSLPPNFPFKAPAVTFTTKIYHPGINEEGAICVPVLRDEWKPTVTLASVLSIVQEKLNNPSPDDPFEPDIAALLKDDRTKFLATAKEWTKKYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQW2</accession>
    <name>A0A9P6EQW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQW2"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="31"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="321" mass="34881" checksum="EE2AC421DBDC9D4E" modified="2023-09-13" version="1">MQSLTKVSAGQTRSGVLGFKRRWIHGSLKRQTSIMMPAMSPLMTEGTITQWKKREGEAFVAGEVLLRIQSDFYAVDVEAQSDGILGKILMPDGSTNVPVEQVIALVARNSNELTMIQNGQQVPSPSMNVPTPPALNALPDPPSVSINPMSLNTNSSPRNLHFSQSSPLTPTMASSRTPSLFEKQTMSGYSYRTIHTSKASRTAKLRVPRLEALSRGIELSPSTSPRVQESIPSPFQMQLQEDVATTPLPSTPLTARWPGSSASLMTSSALPTSKSYLWSASFNEDAPKSAIQLDGDSIRRMIVSNLTANQPTNINELEDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERJ1</accession>
    <name>A0A9P6ERJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERJ1"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="49779" checksum="AA12F1E44CF6F122" modified="2023-09-13" version="1">MRDFPQELVDQVVEFLHDDVDSLRHCRLVCHAWDNSSSTHLFRSLNLLVSASSSLQNNCEVTSPMDRKLAKLKTLLALLKTSTTIQHYVRKVTFGRTSLLAVEDPVLYEQAEYARTLTSVFAHLHRLSDLFFREIDWSTLVGVLRTCILNICQTPTVQNIDIWNCQFPSIPTLLNFLYSCKGVQTLRLTHIRILNLSLNTDREMDEVNATDFGHQDRDTLRSLTIDSVPIPPKLYALLGMKGVIDFTRLSKLCLNNVTDAATIRECLERSGKSLEHLELRTSPFYRKPHDPSTPGPDLSHCPNLRHLRISGLQWTPTLCPAESLSATFANINASAYPLESLHLFVTVIKPRTFIFTQPSSASLSASDSTQTSDSIIEPSAPVSKDLNYGAWSILDSTLVQPQFTCLKSMHIRITPLRAGDVDLSRLSEAFRTIHKSGVDVQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERT5</accession>
    <name>A0A9P6ERT5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rrn7/TAF1B C-terminal cyclin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_742905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERT5"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048538">
        <property type="entry name" value="Rrn7_cyclin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20645">
        <property type="entry name" value="Rrn7_cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrn7/TAF1B C-terminal cyclin" evidence="1">
        <location>
            <begin position="3"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="12320" checksum="02D0C631B748FE64" modified="2023-09-13" version="1" fragment="single">NAPDTLTLHRAAAGFAKSAKAEWGVCVPECNAAGVVWRVVKGMCGGPTLYILTKRVLSALSMPLALSPVFAPFLEQRRASDPKGHRYDDAPPEVQVLVGVVVVLKMVYGLDGFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERY7</accession>
    <name>A0A9P6ERY7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fructose-2,6-bisphosphate 2-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_756686</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="2"/>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERY7"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000005">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="6">
        <location>
            <begin position="62"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="530" mass="59178" checksum="F41CC4F8B0BB1BBD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESS4</accession>
    <name>A0A9P6ESS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESS4"/>
    <dbReference type="OrthoDB" id="1894652at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22209">
        <property type="entry name" value="EMC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21203">
        <property type="entry name" value="ECM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040324937" description="ER membrane protein complex subunit 10" evidence="1">
        <location>
            <begin position="21"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25462" checksum="1E10B1BC971F85F2" modified="2023-09-13" version="1">MKSSSLVVLFAATFLGSAGATENAVLYHRIFHPSFPDLKYLERGSVSGSPPTFQPSESLAEGFKTFSEALQSLEGDPSGVLYQVALARADDKSQATYDFSSVKLCHLNQANKEHIYLHVSDDDTPFALDYFVGPIPKDGSCPRKISSSTSITNFAPNYQKLNTTVVMRRPSMPPLPDLRTPPPISPEGQVVEPVPEKSFLQKYWMYMVGLLIFFLVAAPEEAEQPKRGGAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESZ7</accession>
    <name>A0A9P6ESZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">VID27 cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_843963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESZ7"/>
    <dbReference type="OrthoDB" id="10251113at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="223"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="402"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="760" mass="86050" checksum="700E29AFF7BAC348" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET70</accession>
    <name>A0A9P6ET70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_210915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET70"/>
    <dbReference type="OrthoDB" id="3226250at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="245" mass="28440" checksum="27566C0E12469AF5" modified="2023-09-13" version="1">MRKSRNFLDRFQMRALIEELIKTDPKKTPIQDRNIDWLVARYLQEIHPRGKNSGSRILFLDDDPSFDREMAGEPRRLNHLPHSRIRGQFAAQAEWLLAHMLASSSQSVKMLDITQWVRFCQQSRLDSIAAFLALQKRNRSQSRRDDHEFHWGVPHGQEPPRPSDPYNLCKNLARYGQKEEFWRRALKNATAPKIEKVRTYLALSMSFPLIFCTFSSGAETRSTHLSNFKAPWGSSKVTSTEAVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETV9</accession>
    <name>A0A9P6ETV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_923991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETV9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040422009" evidence="2">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="11547" checksum="8E27EED566861202" modified="2023-09-13" version="1">MKSFLFGTLLAFAIAVTSIAALPLPPNQANPGRNTTPQVGSVDTTSVLSTKHQKPQKTLLKIKNRAGPSWKESSKPKVTFQEPSKTKNTVKFEEQAEKSLEKVLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUL8</accession>
    <name>A0A9P6EUL8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deoxycytidylate deaminase</fullName>
            <ecNumber evidence="7">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_842134</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="7"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUL8"/>
    <dbReference type="OrthoDB" id="6710946at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000035">
        <property type="entry name" value="dCMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="10">
        <location>
            <begin position="247"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="416" mass="46142" checksum="1C08A09570B2F084" modified="2023-09-13" version="1">MRSSLRSTSITPEPTIVRRVANTAMFIAIIGTRFSGKSNVQGYLLTKGFTLVCLLQSNGQPAEENQWLLRPRAGSNATRLRSIDNAAKHASFLSMTPLASPITAASSQYPDDPQTIYFFNTAEMLQHVTENWRKHFVTCDLSSRQLLQPFVRRPFFLIMQIDAPVLERYRRSKNSASVSLADFVEDNDRLVYGTTAGDPQASSSSNSLQSLTDIININVTNAFASIPELHKYLDRLNLLDPEHLRPSWDSYFMTLASLASRRSNCMKRRVGAILVRGNRVIGTGYNGTPRGLVNCRDGGCSHCNFTNKSNLISNECLCLHAEENALLEAGRDRVGVGCVLYCNTCPCLKCTVKVIQIGVKTVVYNLAYKVDDASAQLFKEAGVELRRFDPNSKVHLLPTEDAFALLPPEPQSSLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHR4</accession>
    <name>A0A9P6JHR4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_900349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157996">
        <property type="protein sequence ID" value="KAF9521716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHR4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="353"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9521716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="489" mass="55963" checksum="21D3F6F8F9E3F116" modified="2023-09-13" version="1">MHTTLSDDSLPTLLEDEDDIIGRRDNDETRQYLMQWEDDEVQVNIGQRNQLEFILGRRMTQSVEEEVQTESVETQDEIVQTDDSDISFGVIFMALLFAVNALKEFRKNNNPNVETTRMTTSTSSPMLPIIEGIIRDIAFQPFIEPTLPDSGSSRALVDSYYEGEQTDTGEYQSNLSLADMARLQQWDNGNSDDNIVYPRYSRYTEDLRQNNYANFMAQTVNQRINLLSDQPAIPIRLRTFEEETLPPVNGITMEDFNETFEDWAQLHHLLSDTNISPTLAHALISSRTHFLAYEQLDKLIKEAVETICKMEQRSEESLRLAKHFFDLATDRGLNEVEVIRGILLERNTQQNAQTTVIDEGDGRVETANRMDPPTYALTSDATGDVSTSTRNEPSTSRHRRRRNRNRNRNRSQNQQPVETGFYSPPPPPQFYGITGAGRRLTERNICRNCGNRGHYPNTCPNRLFLQPRQGSFSSTSSGSLPQNTRLQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHW3</accession>
    <name>A0A9P6JHW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157984">
        <property type="protein sequence ID" value="KAF9521836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHW3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="17062" checksum="2D96B341D90E3D94" modified="2023-09-13" version="1" fragment="single">MDNLFMTSGCSRILPPHHLSNPSESLDFGEPKGDAESSAALDFGPSFTQLPQANFGSSPSKLLSFGQPGGDVELSSSKTLDFGPPLTQQSEANLGSIMFKLLDFGELIVDVQLSPSEPLDFGPPLTQQPKAIQQPRLIQQPQGTQQPKVTQRGEVDIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIS2</accession>
    <name>A0A9P6JIS2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_733454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIS2"/>
    <dbReference type="OrthoDB" id="2691851at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="505" mass="56688" checksum="6DA3739B9B7EEAEB" modified="2023-09-13" version="1" fragment="single">ALSLEKALNRLRVHEESWTTLLGLLGNQDVPALHRIFKQCKRRNWSIEKLVEKIRDALAGKYHPKNYSDVEYDLATTIYELGGGATLFALHKSMFAFPCLSTLDERRQEFKLRISIGSLKMSDLFHNIKIMFEDDTPGLRRVGMSLLMDEISCDERLCYLAGTDDIAGLCEHAAEQFSSMKVGQDLEVVRAIAQAVRSGKVDVGGEVFVMAMARNDEVGYGARPIALVVVCKKKTYRHASLTIEMGRQAWRLSPYGDRLHGPIWSIASDGDPKRRPALYLHCMVRELLPTDPLFSQLVGLVGLNLWVGSGGETQDLDFKHNFKRICKCLCAREGILINNVVITKSVLASWFARLTDTDWSEDTAFSLLNNSSGAAQRINSLLSPKDAQDVPRAIKLLTVTADLRKLDNSNFDPSEQVTFHSLSLLGEMLDALVEPFINPDFSLSEQIISLVKFAFIACALFMKHEGDFMPHHLYSDLQCMVRTAIFRVAHTKNLDPSMKVFLCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJG3</accession>
    <name>A0A9P6JJG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP+-dependent D-mannitol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_696430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJG3"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="28"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="173"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="345" mass="37789" checksum="CDAEAEBA97C20F1C" modified="2023-09-13" version="1">MKGTMRALWYSGPREHEVREVPIPQINDDEVLLKVSSCGVCGTDAHIHEGEFISKFPLIPGHEAIGTVVEMGKNVKGFSMGDRCVADVGITCGECFFCRRGNSLLCENFGARGVTVDGGFAEYIKYDKKKLYKINNLSDEEATLLEPAACAIHGLDKLSPPVGVEVLLLGAGPTGLILSQLLKLNGASRVVIAANKGIKMDIAKKLRAADEYLELDRETPEAQWQKLKDDNPYGFDIVVEATGVDKLAQESIEYVRRGGTIMLYGVYQDKARVIWPPGKIFADEITVVGSFSQTFCFPRAIAYLESGKVNVKDMVTDIFTIDTYQEALDKMSSRTALKIAVKPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJT9</accession>
    <name>A0A9P6JJT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gti1/Pac2 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157921">
        <property type="protein sequence ID" value="KAF9523250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJT9"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="327" mass="36919" checksum="FA018709E16CA46B" modified="2023-09-13" version="1">MQHPTLQNVRIRSTRDALQVFHGVATHRVPLITRRLDAEERRNIMPGNVYVWEERGANTEPTGLGMERWTDGMGWGPSRVRDEFLFYHQKDSDAADDLLNPVTPWAQMMRRPGSRPNKPFGPDGRPLPDAERLIKQTYSVHVSLPADRPKGIIRKWHLTAYFSPSKLHELDTIDNIRGVGDLAVPDGWFRSARIGRNRRDSRTIGFAPPSPPDLAIQPIPSGSMDYHHPQINAPYHSYPSPSQHMSTPHPYPSSASPHIYTTSSQVTTPTASGYTTPTSSTSSSPRSLLNEYPHNPKNRLVPLEVLVRTAGPRRDPTDEQLLRRFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK61</accession>
    <name>A0A9P6JK61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_862655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK61"/>
    <dbReference type="OrthoDB" id="2094445at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021278">
        <property type="entry name" value="ATP19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11022">
        <property type="entry name" value="ATP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="84" mass="8969" checksum="EF08F135C2DB7890" modified="2023-09-13" version="1">MSYQLFGRAIKNEYIVLTVFGTTFGGAYLATRGGNNTAAQAKPVNVQQAKESVPINAGSSEEEQFIQNFIREAEKSDAGATAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKC7</accession>
    <name>A0A9P6JKC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKC7"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="38092" checksum="945F64303BA891D5" modified="2023-09-13" version="1">MFTTSPPDIISLPLEIVMEIFSLSVTAREFYTAYHAHQSTRNRKSLPHERSHAASQVCRRWRAIALSTPHMWTDIPIFRTLNSPWKGRDGWNISVVGELSRYLARSGALPIHIFIDHYDFTGLHPIPDNVLKGILSSFFREAHRWRSAVILIDRTILHRLPIPNLPTLKKLNFIARGLIEDSPSYDYLAPVLNALPSPLDVLVLDGQLQPSYTSGTNVIRPIVETFIGLPPRLEVLEPGASRLKKCILRGIHLCEMGLPPPDKRFQFSALISLELNEVHRFKPCVHFEDGSAFDETTPFNHIDAPNLKELIVKCGRVPHDYVHILTEIRQTAVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLX4</accession>
    <name>A0A9P6JLX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_818299</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLX4"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001508">
        <property type="term" value="P:action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000097">
        <property type="entry name" value="Potassium voltage-gated channel subfamily G member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537:SF254">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="VOLTAGE-GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00169">
        <property type="entry name" value="KCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="76"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9525586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="395" mass="44660" checksum="9131D37FCCC09A2B" modified="2023-09-13" version="1" fragment="single">MSTTSNIELNRLRRPPPLSSVRFLTEDISPRGSPHDSSDNLASNNTDDDESLAVEPLWKRTLFQLLEQPTSSPSAFVVHMFTTFLIIFSALVTILETVPTVHSISGRVWFGLETSVVALFTVEYVARCVARSNTWTSLLSWIFSFYGVIDVLSVAPYYLELLLLQDTSVYFRFSILRMFRLLRVFRPFRYNHTILLTIEVMYLSVRRSQHALLAIGFFVIMILTIFSTLLYFAERGTWDEVLGTFVNVDGDPSQFSSIPAAAWFVLVTISTVGYGEITPRSFLGRLITLPILVCGLLLITLPSFVLGREFSDVWEIMSKDSVRTAFLSSPRAPYSAVHSARRPDTPRTPSRDLSNLKLAQNQTELSKQIHELSATVEMQAKLLQRLIKKLDQGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM45</accession>
    <name>A0A9P6JM45_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">guanosine-diphosphatase</fullName>
            <ecNumber evidence="5">3.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_885317</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.42" evidence="5"/>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM45"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24040">
        <property type="entry name" value="ASKHA_NBD_GDA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="137"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="726"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="385"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="783" mass="84965" checksum="2FF429D0D8D8E3CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMD9</accession>
    <name>A0A9P6JMD9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_746883</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMD9"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032889">
        <property type="term" value="P:regulation of vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="14199" checksum="FAAB731861B0B63F" modified="2023-09-13" version="1" fragment="single">MHTIKLVVIGPSGVGKTSLRGKYISGRFTTGYRATIGADFITKTLPHPSDSNQVVTLQIWDTAGQERFSSLSTAFFRGADAVLLMFDVNDPSTMQSMKKWWIDFCDKAPVGEDQMADFCCVIVGNKVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN25</accession>
    <name>A0A9P6JN25_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN25"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="15971" checksum="E6613255F22AC71C" modified="2023-09-13" version="1">MQFQPPLLALNYEGLGFILIPKSEVIRNELRHTTTSDERNRLQRGDQIILDGHDLEHTYELTGIRYQNDQYSHIEMVAFNHAGDYYAEASSVMVPFLIQIETTLLHSNFYFSPRRIESVMSIKSILHHIQQGAQKIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JND8</accession>
    <name>A0A9P6JND8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_870240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JND8"/>
    <dbReference type="OrthoDB" id="3366352at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33526" checksum="6E81D0935E33314D" modified="2023-09-13" version="1">MPAFEPRQFPPPSLSGVPIEYIVQQLHGLADHYWDKPDTADCTIIVPFPHANGRPELPAFSQTSIIEPTFSYASTYEAPVLGRRATQPPLNAVPRVSLSLHIDYLSAHSSYLRGLFSGALPLDLMYSSEPPKSNGSIPADRLPRLMPCSPDHPILFLPVPDPTSFHLLVHWMYFGDFAHIQQCLHEGSIQWEGIARNVEYLGLSPEIKIFLGNWYYAWLNPDRQGEECTAEGNDSDTIFSDSDSEDSCSTASDFDVEPMDGDEIDSEKADAPCRTVICWVGHDGRIARKKPLRFIQGRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNS0</accession>
    <name>A0A9P6JNS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_386607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNS0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9283" checksum="A2A3285867134E3C" modified="2023-09-13" version="1">MPLGVAVSQTGKNGKCSSAATLISSSALLLGSLTFRTCRLVSASTQENGIRYPAYQKGRKGIKKDTFLPYEALTAAQLRKMRGKACN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRF1</accession>
    <name>A0A9P6JRF1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_850185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRF1"/>
    <dbReference type="OrthoDB" id="2987979at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="480" mass="54691" checksum="F6BBD3FFD29323D1" modified="2023-09-13" version="1">MLNMLQNPLVAIHVQKLYIRAWFIQYLLKRGALFGKHSSSTSKSGRRINSRDLFFSSFNIPKTLKPLFRSRGGLGEGKLVETLSPKLILSLMAVAIEGMANATVLDFEWRDLPLNKDTSVFLTATRKTFGPSLRRLALQAPIIMFKELLAIADFPHLDELAFYFDYALESKTRKERKPVEASAELQELLNTLIPFITRRRSTLRTLHISSSSSSDLSIFFLRLPDLPGLRRLNLEIRFDESHLVDSSGILKFLQTSSLLHVRLKPPITISSDVHADGRDTTSTRRDNGWAQLNQKILGHVGCLRRLESLELPFLSLEKTLPLIRRSSDTLTALTLTNKFLSLSEVTEVIHLFHHRPFDLQHLHLEVVSLELVILKLLALRVPNLFSLELVFKEPDRIPEEVFPDESLDYAPFKDWRLYDLGLYLSRYQPPSPETSLLTGVSTPIEETFMNKIQKTVPSIVELKGVERLSPLEALATRFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS41</accession>
    <name>A0A9P6JS41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_850451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS41"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF57">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040364145" evidence="6">
        <location>
            <begin position="22"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="64"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="559" mass="59243" checksum="D2F505C423B7E787" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSV8</accession>
    <name>A0A9P6JSV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSV8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="224" mass="24607" checksum="2C442DD347719C33" modified="2023-09-13" version="1">MPSAAGLPHAGNSALSLAQLAIAVLVMLDIILALSLNVILRLEAREDGETPDLLAGVKRTSKWMWKQFQAVSVRHLPALKELLVEYERILKDLEINLNANKSIRRDRAQIFVQRLDLVVLATKAKIEELNGFLPYPDDPGPNIQNTTTPPGILTNPHGSKGFLPYADDPGPDPSSAAANFFQHSQNVKILGGTFTINQGVSDSKWQSVQQQVSWIQLQIVVLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT39</accession>
    <name>A0A9P6JT39_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_867467</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT39"/>
    <dbReference type="OrthoDB" id="60955at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061700">
        <property type="term" value="C:GATOR2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="151"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="596"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="712"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1164"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="658"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="744"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="823"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="853"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="876"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="894"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1175"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1234" mass="134338" checksum="8D0EB3230183E430" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUC7</accession>
    <name>A0A9P6JUC7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_677055</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUC7"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16473">
        <property type="entry name" value="RING-H2_RNF103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000728">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.4, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051653">
        <property type="entry name" value="E3_ligase_sorting_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168:SF1">
        <property type="entry name" value="OS02G0798600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168">
        <property type="entry name" value="RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="1006"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="403"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="517"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="593"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="737"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="826"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="309"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="403"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="612"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="670"/>
            <end position="684"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="696"/>
            <end position="708"/>
        </location>
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        <location>
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        <location>
            <begin position="755"/>
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        <location>
            <begin position="785"/>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
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            <begin position="829"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1066" mass="113373" checksum="4C16F826D9E8A04A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUJ9</accession>
    <name>A0A9P6JUJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_880673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="19405" checksum="0CBB250659186DC8" modified="2023-09-13" version="1">MSTLPAIETTIRRIQSEPQLQLPSPTNPRASEQLPQLPNQASIPSSSIGGSIPQDTQLDESQKAISVPDTRSVLTRVLAFFGFGQAAPHQRMSTVSVIWSLEQPPPNIPASPSESPVHTVRAKKSNELEQTNSTISSKTNSIALFDNADTLSFSGPTTISANAPQLTFNAQTIYNFSITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUY4</accession>
    <name>A0A9P6JUY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase III subunit RPC9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_846215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC9 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUY4"/>
    <dbReference type="OrthoDB" id="1746530at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038846">
        <property type="entry name" value="RPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561">
        <property type="entry name" value="CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="217" mass="23617" checksum="6E5BA3B5DC01A56C" modified="2023-09-13" version="1">MEVVNQRAALLSNYEVLTWLRELESDHLSRTKTALRIKKEEEISGTNIPGSTPASSGHLEATENLRTVEVEAIGYLSSDYLPTSSQNEDGITSLVKSLADHDLTKAEKLQIVNLAPTRPVELYVIIEELEDRLGDQLDEILGKVQNSLAESGNASSAMANGVITTKSTTTNDPESTPIVIEQNTAWAEDVDAVYDDEYFDDTGAGAGVEGDLDMEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVE3</accession>
    <name>A0A9P6JVE3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_844219</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02736">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02583">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035698">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035697">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="15">
        <location>
            <begin position="244"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9534421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1402" mass="156530" checksum="F6E410E186E420B0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVM0</accession>
    <name>A0A9P6JVM0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVM0"/>
    <dbReference type="OrthoDB" id="2893938at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="41"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="517" mass="58768" checksum="0B02198084F5C363" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWE3</accession>
    <name>A0A9P6JWE3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CBS-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_779613</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWE3"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="726"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="139"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="206"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="314"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="394"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="543"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="753" mass="80526" checksum="59A5C679332FF8F9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX85</accession>
    <name>A0A9P6JX85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_842337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6058203at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF561">
        <property type="entry name" value="PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="6">
        <location>
            <begin position="86"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="405"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="734"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="317"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="513"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="640"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="817"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1167"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1405"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="688"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="706"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="835"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="884"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="908"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="978"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1040"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1061"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1090"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1167"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1212"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1243"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1260"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1408"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1426"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1441"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1494"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1505"/>
            <end position="1519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1549" mass="166148" checksum="6148898136349429" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC42</accession>
    <name>A0A9P6BC42_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158137">
        <property type="protein sequence ID" value="KAF9521309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC42"/>
    <dbReference type="OrthoDB" id="2635829at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="53828" checksum="EC7DEF377F5AB705" modified="2023-09-13" version="1">MDDDSVNSPQPLESIPDGLDLTVFGDIVYPKDAETVIWPGVNIRTTLPFVAGSPAIPNILFEDAAHVKKLSETVQTEASWIVEMRYESGDDEEFARRIRVELCRNHVVVIKGHPFEPTPLTASDIRKTFGIEETRAVVSSDAILRSKPNAQMIHVAQTMQEFCDATANHEIVRCLLDLPNSYVHPHRFLLALDDGRKARDQSKDYFHHRQYNPTDIDRAMLWTLIHHGMYHTYIHHDAAGYATWVQIRSGMKVWVVVRPSGFEDVKCRSDIRRSLQTIAQDSITFDKNAVRIAIYATPGDIIIQPPGTLHEVYTPVPTVAIGGHFYSLDCLYLTEMNRHYDLDYPDLSNNDHPHVYQLLVLMMALLPLQKGRQLSLKNLQALVTMVKNPKRYQVNVLADPDAMVLKIKGKFDDRVFAETVAEALLSDIICKLTVGSFSKNKDRKGDYLFHQLTGLDNAGEIVDWESALARFQANGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BD49</accession>
    <name>A0A9P6BD49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_778996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158233">
        <property type="protein sequence ID" value="KAF9521235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BD49"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9521235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="163" mass="18366" checksum="901E11B5F03686D8" modified="2023-09-13" version="1" fragment="single">RSFERDIIPMARSEGMALAPWSVLAGGKFRTDEEEERRRKTGERGRTIFHPEWQRNDQEKAVSKALEKVASEVGDKHIAAVAIAYVMQKTTNVFPIIGGRRVEQLEANIEALSITLTVEQIKYLESVVEFDPGFPITMIVSSFLPRLENFPSCLRAMVPGFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3W6</accession>
    <name>A0A9P6E3W6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_141713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157962">
        <property type="protein sequence ID" value="KAF9522074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3W6"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="37882" checksum="38675F3A0841F602" modified="2023-09-13" version="1">MSTNPSTNHSAITDTVSLFAGLPMFILTEIPLRLLSTTTTHLEANPINFLLGHTAPDALVDSGDRRDPPQCSPETRDSILREIKKWANSREGATLIFWLFGSAGVGKSAICQSIAEMFKRKGLLLGNFFFSRNGASTGRSNGDRLLPTLIHQLQEAIPETRSCIQNPIRRDPTIFTKTRASQMAVLYVEPLKKLKIRGFFQRHNVDLWKKVRLVVIDGLDECLDTDVQCDLLRVIAEASKALPIPVRFFIASRPEVRIKDTFYSHSSFHTVELRTIDLDQDQNARQSVSRFLLDEFAKIRKIHPYLHDSWPSEQVIQTGHSTFTVRPTVSAVQSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E416</accession>
    <name>A0A9P6E416_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_777457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157957">
        <property type="protein sequence ID" value="KAF9522164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E416"/>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF115">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="16"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="13106" checksum="49366D465970B361" modified="2023-09-13" version="1">MQPARTDLAPPKDDPYTTEELKKFDGSDPSKPIYVAIKGSFYHFLARRADVYGPGKSYSVFAGKDGSKGLGMSSLKPEDAVADYSGLDEKDMKVLNDWHSFFSKRYNIVGKVSDSNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E418</accession>
    <name>A0A9P6E418_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily multidrug-resistance, DHA1 sub-family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_736702</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E418"/>
    <dbReference type="OrthoDB" id="419616at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040490847" evidence="7">
        <location>
            <begin position="36"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="20"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="51890" checksum="D3B7C26E33C6BD80" modified="2023-09-13" version="1" fragment="single">DEETPLLHGKQRPTPLPWFQLIIVLVLQLAEPLTGQVISPFAPQLIRDIGITHGNESQVGYYVGIMHSLFFLCEALTVLHWSRLSDRIGRKPVMLFGLFGLSLTMYCFGLSRTFWGLLLSRGLNGALNGNIGVVKSMVAEMTDSTNISKAYGYMPIAWSLGGALGPMIGGILARPVENFPELFGNSEFLQKYPYFLPCAVPATFTVFAWLLAFFYLRETLPNPQPISVFLAFCRSSKAGANTSEVASVEDMMEDSSLLEYKKPLPLRSVLTYNVILAGANYATLSLVDIAFRAIQPLFLATPIHLGGLGLSPPEIGQVLSFLGILNGIFQVFFFAKLHDRWGTKPIFLTGVTLGLPCFALFPIINLLARHQGYSTSVYLAIGLQTFLFVVVNSGFGAIFIFIAAASPNRASLGATTGLSQVLVSVTRAIGPAMANSLFSFSMEKGYLGGYFVYYILLVITGFCIYVGWLLPRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E420</accession>
    <name>A0A9P6E420_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_777589</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU157960">
        <property type="protein sequence ID" value="KAF9522112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E420"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF511">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="78"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="34596" checksum="43642F2F669CBDB6" modified="2023-09-13" version="1">MTISTLPDVTEVVKDQIYLGDLKSARCPEQLSVLGITHVISICHDSVNYLSSSKVKHLRILVKDSETEDLLIHLAEACQFMDHALRPSVGKRGMVFVHCMMGISRSPTVVAAYLMKTMNMSRPETIRYLQKFRPQVHPNYGFVKQLDVFANCSYEPSHHHPLYRSWKRRHLQDATSYLNYIHDTSELVRDKVFLSTEFPSETIQAQSYLGDLNIAYVLSISPAAHIVSDVLGVHAHQVELPDDSADSMLRVLPEIFDYITQAMERNGPLLIHSTNEMRLYTVACAFCANSLLSMFNLVLIMVILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E585</accession>
    <name>A0A9P6E585_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_776724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E585"/>
    <dbReference type="OrthoDB" id="3261031at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="301" mass="34964" checksum="CF7A5390F5E95434" modified="2023-09-13" version="1">MTRQYESAKKYLDEELFPCRAQWAWAYTAYKFTCGVRTNGRVEGENRVNKTIGGPKKSLKQVFDGLNERTDGQVFPGPLQIIRTHVGPYGLQVCFKQMQESVYYRTKVLQLPEGMHDWHMMNTFENDEIHISTRWLIRLIRDRGLSVQHLYRVESIGGQSLHMIAILSDGNYACDCCMGTNLGLPCRHYFQVLSSMPTLKFSLGIIRPRCVIYCYEITSLSEEIDGIKIKTLNLVRSLRLLPVKDKHLVRSNYLESIPNYKLLLCRIHCIQQINPPTQHLHQHRQFLLELHSTKPMLPSDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E597</accession>
    <name>A0A9P6E597_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_742271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E597"/>
    <dbReference type="OrthoDB" id="3192097at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="55" mass="5963" checksum="611D7F15E2B86DD4" modified="2023-09-13" version="1" fragment="single">MARATAGIWIWDILDSAYFFFHAHFTSGLGDMLGSAKINGMAGHSAVRGDRFSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5U5</accession>
    <name>A0A9P6E5U5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5U5"/>
    <dbReference type="OrthoDB" id="3063824at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="28466" checksum="CC1E7A6249A84B80" modified="2023-09-13" version="1">MEEYTHGLSEESLGDDSTMHPNHSTTAQDGEHNTRSPSFAPKDGSARKKIVYLCVHGSKNYLHYAVVPLPSSYQDAKKTAIDVLGGYLGYPNIIPDDIYLRYGIKRGSGLHWAYIKPDFWDQVITGGEELRIVRKVKSGQDEVEIESEQQKSLFVTFRLGKNAQASPRDKYARMLLAENDFETKKSLVKLFCQSLTPMTRAANLILFAVIKNQDGRWVASVIDTSEGLWKKTILECKKENPHFEILVVESPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7D9</accession>
    <name>A0A9P6E7D9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_798747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7D9"/>
    <dbReference type="OrthoDB" id="2993106at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="626" mass="66538" checksum="374A5A642B042931" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7I2</accession>
    <name>A0A9P6E7I2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD/FMN-containing isoamyl alcohol oxidase-like protein MreA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_774880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7I2"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040330695" evidence="3">
        <location>
            <begin position="20"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="144"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="624" mass="68010" checksum="DF96918DFA7F687B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7P7</accession>
    <name>A0A9P6E7P7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_641030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7P7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="86" mass="9512" checksum="339581061A148939" modified="2023-09-13" version="1">MPRGKPPWILCGIGTTLLGRTWTEIPISFPRHHHLLTSPVRGRSSYSLVGTVFLFSCRPAALAHKRIIQCSGRCIGFLKFTQPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E860</accession>
    <name>A0A9P6E860_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_897952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E860"/>
    <dbReference type="OrthoDB" id="2962374at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052759">
        <property type="entry name" value="Metalloprotease_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43579:SF1">
        <property type="entry name" value="NEUTRAL METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M4 C-terminal" evidence="6">
        <location>
            <begin position="138"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="335" mass="36167" checksum="F86CF1CA0D873E53" modified="2023-09-13" version="1">MTSQAVDDVAPNHVTCCSVIPTYILSKIADSPDAPDVAREHARNALVHSRTLIQRHQESITRQINASQAQGPSHQGIVPDYIVNSIASSYPAGSEGEETAQRALSLSAEIRDNREAQANSLSDVIGHELTHGVTQFTAKLLYQGETGALNESISDVFGGGLVDRRRGVHVKGEGEALRSMKAPGTAYDDPVLGKDLQVANYADALASELPSDFDEGGVHVYSGVPNRAFYLVATELGGYSWDRAGKIWWAALTDCRLTPSSKFQAFAELTIEKAGILYDRSVKAVVEHAWKEVGVDTGAKGEPVPKPQHPQGRNVLISGLDSRWITETLPDKLQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8B8</accession>
    <name>A0A9P6E8B8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_897973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8B8"/>
    <dbReference type="OrthoDB" id="3039272at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="831" mass="87156" checksum="4696F08C8B82DC4F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E992</accession>
    <name>A0A9P6E992_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_595361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E992"/>
    <dbReference type="OrthoDB" id="2558918at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20532" checksum="40D719B6BF514CEA" modified="2023-09-13" version="1">MAPPPKKEPRTGFFASPRKILYAFTFGLIGACTAVELGLVSQQLHHYGNFLSRYPTQEYKSALDLLLFACLWQLLIVIFHYQLPSLLVAFATLSSGVFWGAGAGIIERVSPFEFYNCGEPASYFNSIWAPFKHECARIVTIQGFGWTLWALSVFLLLGIIVDNVEFHVKTRPFYPLTDEEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9K7</accession>
    <name>A0A9P6E9K7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_748466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9K7"/>
    <dbReference type="OrthoDB" id="3034725at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="225" mass="25896" checksum="5EDDC28B3E9379D7" modified="2023-09-13" version="1" fragment="single">TSSLATFLYPVYFAYWYGMETGNLVPFKMVAPPGVPEDKMDATFKCEYMYIFDLTCDKLLPSLLEQFEDHVKAHPDFNIGNRGRRAWQDPRGTYGKSKLNVASRMFARRNPYNARNSPNFTAPYTVHPWILNVLNLQTKKVLIPNPERPQYMEFLDGKIRRVDQSGAQAFRKGNVIMMSFRMGMAVRGDNWFSEIIPLEFIRVASMPTNSSSDSFSYPTDLAFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9L3</accession>
    <name>A0A9P6E9L3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_819338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9525014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9L3"/>
    <dbReference type="OrthoDB" id="411632at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="409" mass="46420" checksum="D22747E5D8F69EB8" modified="2023-09-13" version="1">MRRLRCKGLTFLAAFAAFNLFIISEYIQPRKVALSLDLVYDPPTSNPAQDLAQVPFSSTPRVLLVSALFPQIDQSLSQDKVATWTKNFLGQIETDIYLYTTKKAAPSVHAARVPGGKLIVDTSFASPFDVHPLRGRRLVYERMRQLDPSDNPSAERYALRNAKPFFLERATQNVAAKAHYDYVFWVDFNAFSEHHVYQNWPDTTRLQQIWKEGTSLTDRRREDLFFFPVNDGPPKESGSWTEDLGPIDAHFAEGSFFGGPPSAVRWFASMFYAYHNHYLTLGFFIGQDDTIYNSLLLLSPSRFITVWASDPTAPARGGLPPSFVTHGPLGACGSSSKYYQWWLSDRATRESMGEWWIGHGAEDDKEAVGWWKVRIACRLTRVLSAEQVLRTALGSRWKATLPTMFRLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9M2</accession>
    <name>A0A9P6E9M2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_860445</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9M2"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040240766" description="FAD-binding PCMH-type domain-containing protein" evidence="5">
        <location>
            <begin position="26"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="76"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="515" mass="55214" checksum="E1CA422EF309F30E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA41</accession>
    <name>A0A9P6EA41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA41"/>
    <dbReference type="OrthoDB" id="3263055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="172"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="35178" checksum="17F89256BA380628" modified="2023-09-13" version="1">MLTPATLDYTQPLDNSMGAFFVGLLVSALLHGVCLIQAVQYFQKYPTDQWFIKAAVVTTISVDALHLILTSAGVYHYVIQHFHEPERLEYLTWPLLIEALLVGVNASIVQTFFIYRIWRMSKGNYILCGIIAFLIVGEVAAGLTWVILTMQMETWLQLLKTEPVAISIDVLSCTIDVLVAGSLVIMLHRARTGFKRSDTIINKLIIFVINTGILTTIFAFCALISVIAAPKAMYYAGFYFCIGRLYTNSLLATLNARNSVASSGAEDTELKASSITPRGTLASHSRNINIRIETTQEAVREGEKPVHGHSEWSREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA57</accession>
    <name>A0A9P6EA57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA57"/>
    <dbReference type="OrthoDB" id="1043111at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040015">
        <property type="entry name" value="UBL3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039540">
        <property type="entry name" value="UBL3-like_ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13881">
        <property type="entry name" value="Rad60-SLD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="148"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="29282" checksum="EFB7DF6D2A50BE7F" modified="2023-09-13" version="1">MTGDNEVSGPSGASNNENRALEVPLRPPVPHFAAGSSGVHDALPSSARTSFTHVNHDEDEHRPRQSLAQEPSLAAVSAMAHSAQNATNGSSELQSSTSGAVGLEGVPLDPQSKILETSMSPQLTSTSPTQPHEKATAEEEAVPQMPQTYVTFLLISGRRRTMSFEPETTIGRVKELVWNSWPSDWQDERPPAPSYLRVLYLGRMLQDDETLSKLKLPVSVSAGPTPTIMHISIRPIPPPGEGDMKKKKRRGIDETGNEEQAGGAGCCRCVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAG1</accession>
    <name>A0A9P6EAG1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane amino acid transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_771930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAG1"/>
    <dbReference type="OrthoDB" id="655540at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="14"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="419" mass="45423" checksum="4D114FE758DD434B" modified="2023-09-13" version="1">MRSSKSIRPSCNGQSTFGQTLFNSTAMLVGLGMLSEPLAFAYAGWIVGTFLIFSYAFVACYTAKILARLILADPRIRSYSDIGRKAFGSRATPMISFLFCLELFSVSVVLVTLFGDSLHSLMPQYSSNFYKAWGTILLIPMVFLPLSLLSYTSILGILSTITLVIVIFIDGLSKKEGPGSLFSPQPTNLSTQGVVPLGVAFGLFMAGFSGHAVIPSLARDMADPSQFDTMVNWSFIIATCIYTIIGYVGYLMFGNNVSDEVSIDLLATPGYNSSLNTLCLWLLVVTPFSKFGLNNQPLNATIEILIGLDSPITSPEHLAEEPDRLSGTIPKYSTLLHRKRLLSVLQRIVVTSLSVTASISIPNFSSMMAFLGSFSAFTICIIGPILAKVLIEGNCSRFDIVVLFVGSIMVIWGTIAAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC40</accession>
    <name>A0A9P6EC40_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ketol-acid reductoisomerase, mitochondrial</fullName>
            <ecNumber evidence="13">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Acetohydroxy-acid reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_857992</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 14">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="13"/>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC40"/>
    <dbReference type="OrthoDB" id="10255643at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000003">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000005">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000167">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016207">
        <property type="entry name" value="KetolA_reductoisomerase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000119">
        <property type="entry name" value="Ilv5_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 13 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 13" id="KW-0521">NADP</keyword>
    <keyword evidence="10 13 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="15">
        <location>
            <begin position="91"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="16">
        <location>
            <begin position="282"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9526371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="47821" checksum="8030E62D4187B7B4" modified="2023-09-13" version="1">MNSKTSNETFLEPELPLYLFFALIMASFTRAASQTLRAASRRAPRALAVSAAQPTQRASFSLLARAAAAKAAQNSAPQGARGVKTLDFAGTKETIYERADWPLAKLQDYFKNDTLALIGYGSQGHGQGLNARDNGLNVIVGVRENGESWRQAMEDGWVPGKTLFPIEEAINKGTIIMNLLSDAAQSQTWPTLAPLITKGKTLYFSHGFSVVFDKDTHVIPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVWQDVTGKAQEKAIALGVAVGSGYMYETTFEKEVYSDLYGERGVLMGAIQGLFLAQYQVLRKNGHTPSEAFNETVEEATQSLYPLIGQKGMDYMFNACSTTARRGALDWAPVFEKANLPIFEKLYQSVRDGTETRKSLEYNGRSTYREDLQKELDEIDNQEIWRAGKVVRSLRPDYKGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECN5</accession>
    <name>A0A9P6ECN5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECN5"/>
    <dbReference type="OrthoDB" id="2662290at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="419" mass="45794" checksum="82CD8E7362D3AD86" modified="2023-09-13" version="1">MSQYPPEEQAQAGNSISLFAGAQNVNITGSQIHVHAPPPVQPSQAQPLPTTAPSVPTQPPHVVYQSQMLHKGRGFPLWYPSPNVNLPVKYRLRGISIGDVGYFTPEGGFEFLFNILLPANHSINGSASNVPKGFVPHSPLNPRDIREHWDFEAGAYICSPSVRASRVESSGLMFRSTNSEGAILTMPNGACKTELSSTTSFQRYATQHAESWYQFVHSRGRDVANGELRLVYGCDTSTTWSVAAFSNTANVELKFSKTQGGESSYSWEHSEMGETTRVGPGVHDNEGLGPQGESPRNQCLFLRAMTVTLSNQSWESLGFEIPAQSMFQDSSLSRSDQVSLWSMDPATIPDTGRVFRLLSNLHAVFQLHALDTPSLDISGVASVFKRASTQNQSRFSTCNISLRVCDGVPLLLACKLMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECZ3</accession>
    <name>A0A9P6ECZ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_769747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECZ3"/>
    <dbReference type="OrthoDB" id="2970937at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="17986" checksum="1548E487BF44A957" modified="2023-09-13" version="1" fragment="single">MELYIKPLKKLYVRNFFRRQGFGKKVCLVVVDGLDECQDSDVQCDLLRVIAEASKIFLIPVRFLIASRPEVRIKNTLYSDLSFHTVDLKTMDLDQDPNARQSVEQFFRSEFDEIRKDHPEFLDSSWPSEQVIQFLIDKSSPQFIFASTIIRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED18</accession>
    <name>A0A9P6ED18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome assembly chaperone 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED18"/>
    <dbReference type="OrthoDB" id="2546621at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31879" checksum="7A120EEFD306B157" modified="2023-09-13" version="1">MDVDPLADTVPPRYALESDEEEDEPNPLHIKDPNEETTKFEIKIIGQAKEAKPLIVASEDAGRIWAKGADLGEQVGAVAVNNIQIGLIFNPAWTSSTIIVSESFSRLPLTVMHSFAQAVFASLKPKNIAILDTYPLPTYVSNTRSSFYDAPLRYLSTSGATGFLDKEGVQPFAPPNLIQSTSASFLSIASLPSSSDSNTLLLLPSPRIPSHRPKQIEKNEFPSPGSDQDEDFEWSIDMLSKVHRLLFDAIGEQDVASRKVWKLAVRTDQAEAKEKSPRKNVHIGDSGMYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDM9</accession>
    <name>A0A9P6EDM9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-dependent bile acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_793597</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="848"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="895"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="960"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="987"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1072"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="140"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="558"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="853"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1166"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="505"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9527181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1428" mass="157859" checksum="C0A3C60AC0ED1533" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDQ8</accession>
    <name>A0A9P6EDQ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDQ8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="126" mass="14224" checksum="32AD560FE4E0DB72" modified="2023-09-13" version="1">MEYLPKTPPRRLVPRGEPDWTPSDQRRAIAYIHRRTLMAGDSPTPGGLPNTSPSPIFTKIMPLKLPIYPQPPSKIPLPKETRPSFQLDLEEDNPFAPKKRLSSSLYFRMCSVDDSIDVDNSSSSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE14</accession>
    <name>A0A9P6EE14_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycolipid transfer protein domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_856355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE14"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3520.10:FF:000001">
        <property type="entry name" value="Pleckstrin domain-containing family A member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22652" checksum="9483DE91D230BF5A" modified="2023-09-13" version="1">MAPYLESVTSFADVPVTDAGVDTVKFLEASDGLVGLFDLLGSTAFSVVQSDLRGNIVKVRTRYEATPQQSATLESLVENEKAEKKRTATEGLMWLLRGLSFTCKALQNAQANKDQELAQNFTKSYEDTLKKFHNFVVKGIFTVAMKACPYRKDFYEKLASDPSGGPPATQDKLNTELDKWLAALSSIVTRMENFYEKDGHNKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEN8</accession>
    <name>A0A9P6EEN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_394366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEN8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="82" mass="8964" checksum="545B3862C0C88616" modified="2023-09-13" version="1">MSTEKPATEATTSSDTLQQLAPSSIGDDVSIARNEVELVIAESFWKSCRIESRGEVVIKAASRTPQGWSTIEVGKHRCSERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EET0</accession>
    <name>A0A9P6EET0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EET0"/>
    <dbReference type="OrthoDB" id="2124139at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="16066" checksum="1F89DD6BD32F076F" modified="2023-09-13" version="1">MRHRGHIPDNAVSVDLDPKNAMLMCHNHKLAFNKYLFYIRWIPSSDEFLIVNHSQSEEYEDIHGRVLRFTSRSPYPTALLWHESRVRGFNPTCGDHFVSLKRKAPECKASRSAHRGTNASEVTMSFTQPLSWAPTVLQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEY9</accession>
    <name>A0A9P6EEY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thiolase, N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_814998</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEY9"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF10">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="292"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9527789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="416" mass="44403" checksum="746ED3284403693A" modified="2023-09-13" version="1">MDRVKQLAAHLKGSSTGLAALEVKRADDVVITLAIRSPLCKAKKGGFKDARTDELMLEMFKHVIESSGVEPAAVGDICIGTVLTPNAGYFARASMLAAGFPETVPVQCINRYCSSGLMAVTTIANQVRSGQIEIGLAIGLESMSENPDNGGPEFSELISSNQAAQDCRERMGWTSENVAVDFNVTRQEQDAFAAESFQKAEAAQKNGYFTKEIVPFTVLRKETGSEKRVPVVVKEDDGIRYGTTYENLAKIRSAFPQWGNGTTTGGNASQLTDGAAAVMVMTRREAEKRGLPILGKYITTAVAGVAPRIMGIGPVAAIPLALKLAGLEPKDVDLYEINEAFASQCVYTVKKLEIPMHVIAVNVNGGAIAFGHPLGCTGTRQIVTGLNELHRRSEKVLLTSMCIGTGMGAAGVFLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF21</accession>
    <name>A0A9P6EF21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF21"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040257832" evidence="1">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="62" mass="6117" checksum="147EC70FBC8AF99B" modified="2023-09-13" version="1">MSFGLKLVLVAVFLAQICAGLPAENTAPSDPNAVNRPAGATWYAMVGNPAPDSSESGAGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFW6</accession>
    <name>A0A9P6EFW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFW6"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="625" mass="70644" checksum="C3F29BC23CCC9CB2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGF3</accession>
    <name>A0A9P6EGF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_303146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGF3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="94" mass="10194" checksum="FFCB07A9B717D6E7" modified="2023-09-13" version="1">MTFQSNSPGIPLISLTNLDFGVITDPFLLVRSRFTQLASTKMAIYSTRQQPYPEQLAALSKNPYLPPAVQAGLLDISLTDEEWNTGAVYCAGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGT4</accession>
    <name>A0A9P6EGT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_766082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGT4"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9528780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11981" checksum="CF2DF3341222F0A2" modified="2023-09-13" version="1">MRPTQILAKGRSAWKGPYFVPFSGLREALTNHESITTQARSCTILPSFVGVRFLVHNGKDYTPVLVTQDMVGHKLGEFSFTKKNFSFKYVFYPFIFRLMLIENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH53</accession>
    <name>A0A9P6EH53_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH53"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="68"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="520" mass="58688" checksum="CC067211AC92CB75" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHH8</accession>
    <name>A0A9P6EHH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_853328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHH8"/>
    <dbReference type="OrthoDB" id="3007819at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="559" mass="62286" checksum="57ED43D037A5AB0B" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHK2</accession>
    <name>A0A9P6EHK2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_893761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHK2"/>
    <dbReference type="OrthoDB" id="249099at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="25098" checksum="2142B158150BE22A" modified="2023-09-13" version="1">MASILYRQYVGESDLPYIMRLVQSELSEPYVIYTFRYFLHQWPHLSFLAYPSDSPTGEPVGVVVCKQSMHNELANRGYIAMLSVDKKFRKRGIGRYGINTFGADLFYLPFSIIATGLVRNSIEAMKQDGVDEVVLETEYDNFAALSLYESLGFIREKRLYRFYLNGKDAFRLVLAIPPSDDEDNTQSASPNRSNQIRHLSNRAICVSPYSDDEDEESSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI50</accession>
    <name>A0A9P6EI50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_764683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI50"/>
    <dbReference type="OrthoDB" id="3265433at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="10939" checksum="22371E9B6C705488" modified="2023-09-13" version="1" fragment="single">VYRVHWLKSRAQAMRWQEELKITRNEMEWTTRYFLYRAEQWRVWAGCNDNSSGHVAYARRQADMWFQFLLSAQSRFLQVNPDYHPVVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIB6</accession>
    <name>A0A9P6EIB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIB6"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="37923" checksum="64D13D559F1E6755" modified="2023-09-13" version="1">MASNSTIDFSKMPNPLAPEAWLSPEEADKHRTYIYVLVSGLCVVLWDMLSCFPEDFTITFRRRWSLYTVPFLISRFFTLGFLLAGTISSTREVENCQTANLVDCAFNLVTLTSINVLLYFKACEVYKNQRCVVAGLGVACVGMLTGPILDFFALLGRHIEPTLYCQLVVQKPSLVVTPILQGVFGLAICFAIVHKLALPSPGDSSHHSIKWRSAFCDIRETATSIRERYFKDEQLYLIIAALAKIPTIVAFCVFRGSNTATQITFTILDLSVVSIMIAKVYRKPLLGTPAPPKNVAPVTTIDNLDFLKGSTGSTSMSTQEAKILQDIQRDVGEDIKTKPEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIJ0</accession>
    <name>A0A9P6EIJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_926278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIJ0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040409394" description="Lysine-specific metallo-endopeptidase domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="660" mass="73320" checksum="A1C7E8B98326121F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIQ0</accession>
    <name>A0A9P6EIQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_852195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIQ0"/>
    <dbReference type="OrthoDB" id="5512at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="158"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="254" mass="27896" checksum="72475F191945D9C9" modified="2023-09-13" version="1">MSDLLGGDFASFTSGRNNNDDIDFDAAASAFPDISLDGDIPSGPSGGGGDDSGFSFDDFDAAPPMQTQTAVKVTGDDDIEKFESDFPEIDMPQQAPSRQYSAPTFAPVPQPSTLSSTPILTQTIQEDEPEVIRAWREKQQAEIKARDEASKRRRDETISTAERDIEEFYENYATKKEKAIRENKNTESEFQAEQQASLSSGTTWERICTLVELQNSQSKTIARTGAGTTDLTRFKEVLLRLKREGDKAPGAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIT7</accession>
    <name>A0A9P6EIT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIT7"/>
    <dbReference type="OrthoDB" id="3019007at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040217478" evidence="1">
        <location>
            <begin position="29"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="119" mass="12756" checksum="5380FA1DC64B0E58" modified="2023-09-13" version="1">MRVQWQINTLTLFSAFFLSTLFFTSTNAARLCTTECRLMKPVCPSGEAPSGVAGCWGCCMPISTFKPKPKPVEPPTPTPSSTPEPIFCTDQCRVTEPVCLAGEKATGSEGCWGCCQPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ06</accession>
    <name>A0A9P6EJ06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ06"/>
    <dbReference type="OrthoDB" id="3235759at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="248" mass="27930" checksum="2AC311E2613447C0" modified="2023-09-13" version="1">MATPTQGPSTRSLPDGQLTTVTNITKSRFQNTKQSVDANANAIDALNGQTMQIALLGEVGTKQEIADLRQQMRDQDQKHKEGISEIQGILDDFLKTQVVNSMRKQVEREITGQIDELVKEQVAECLKAHIPHDLQEEVAGSRRELEELNLALHNSESRRANGTLRSNKPDDLLATLLMPNGNASSHFPKDLRSLFSLDAETLKLLMEDYGIPNSSHKRDYNLNRFMQFCGVRYQLVEQYTPSCTSQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJI5</accession>
    <name>A0A9P6EJI5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_851247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJI5"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000016">
        <property type="entry name" value="Glutathione S-transferase F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900:SF3">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01154">
        <property type="entry name" value="Main.5:_Phi-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="90"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="218" mass="24871" checksum="20F85D377DD972F2" modified="2023-09-13" version="1">MVLKLYTYHNSINAKRVAITLHEKNVPFELHEIDVFTGQHKTPTYLEKQPFGQVPYLDDNGFILYESRAISLYIATKYADQGTQGLVPTEPKANALFHQAVYSEITNIEDPAYKAVVEKLFKKALAGLDPDEEYYQKLITNLDSKLDVYEKILSKQKYLVGNEVTLADLYHIPYISMLPATGCHSVDSRPNVARWFKDITSRKSWQAVKDGIKSTSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKF2</accession>
    <name>A0A9P6EKF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_190323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKF2"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF24">
        <property type="entry name" value="LANOSTEROL 14-ALPHA DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="489" mass="54894" checksum="89F1EDB8EE6F363B" modified="2023-09-13" version="1">MPYSVGLHSAAAAFLSAGFATQFTIAVLAFLFIVTLISAFEKEGVDEPKHLPGFSFSHILPFFTRRYDFLNWGIQASGSNIYQFKLFRNTVIVVSGERARQAYFSAKNFDLTEGFKILSGAIPMVRGVTSDLQTKRVVTIHKRLGNIQRNVPLSSLFPYLLEDTRKCMDSWGQSGKFDPFDKVYELVFQLTIRCLSSTEIADSPELVARLKVLYDKLDNGTTPATVLLPWLPTPAMIKKLWATKEIYDIVTKAIRDREASGIVRDDTLQMLLDSSDEKLVVVGFIMGLITAGARATGSMASWVFTFLGGHQDWRSKATSEVESLLARYSNNAGDHLDSEAKKDPIPVSTRLGLIPLEAWESETPVLDAIIRETTRLAQPHTAMRRNLGPDTYIDGRIIPSGAYVIYPFSDVHLDPEIYPDPWRFDPSREQVKDIPFTYIGWGGGKWLLLAISREHVRSRYWQLIFVFLVCVAFSTRLASTLVFGCFATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKQ8</accession>
    <name>A0A9P6EKQ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Leucine-rich repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_75971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKQ8"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="502"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="687" mass="76697" checksum="7DA4EC5A6E356D62" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELB4</accession>
    <name>A0A9P6ELB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MBOAT, membrane-bound O-acyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_149233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELB4"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="514" mass="57241" checksum="C70B14B61CDE8206" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELQ4</accession>
    <name>A0A9P6ELQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_848356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylthioribose kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELQ4"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34273">
        <property type="entry name" value="METHYLTHIORIBOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34273:SF2">
        <property type="entry name" value="METHYLTHIORIBOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="360" mass="39563" checksum="931E8EFCEC3F9D3A" modified="2023-09-13" version="1">MSTSTKFDLSTESGVTAYLSGTPFACTGVQELSGGNANYSFRLKLCEPYKDRETAVLKHAKPFVKSMKEMTFGVERQIYEVAALRQVRSWLPNDSVVTVPEVYHFDEDEHAIIMEDAGINSMTLKAFMKEGKATPALATNIGRGLGAFLGGLHTWGKGNIMACKSVEGNQHAKDISAWYFFGRITETLRGAEDVPKLSDPPLDIRESDFQVLDKIQEDTRIAMLAAQDSFVQGDFWPGNIMIALDQTGNLKNAYVLDWEAAKAGLPGIDAGQFSAEVHLLRRFYSDACGETATILFDSFVQEYKRVGSPSSEDMRLANIQVGAHLIVLAARVPWGEKELTREVVREGVTMVVSGSGILNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELV0</accession>
    <name>A0A9P6ELV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_904788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELV0"/>
    <dbReference type="OrthoDB" id="3068811at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="722" mass="79731" checksum="98F2E3D4DF6C30D4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELV1</accession>
    <name>A0A9P6ELV1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">4-nitrophenylphosphatase</fullName>
            <shortName evidence="5">PNPPase</shortName>
            <ecNumber evidence="3 5">3.1.3.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_849493</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21664"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57917"/>
            <dbReference type="ChEBI" id="CHEBI:61146"/>
            <dbReference type="EC" id="3.1.3.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.41" evidence="3 5"/>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELV1"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000039">
        <property type="entry name" value="Phosphoglycolate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00050247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00066659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="296" mass="32334" checksum="3D841397EF8403C8" modified="2023-09-13" version="1">MTVRLSTAEAYGRLFDDYDTWLFDCDGVLWRGDHLIEGVVEVLDLLRRRNKKIVFVTNNATKSRKSYKSKFDQLGVQAHVDEIYGSAYAAAVYISSVIKLPKHKKVYVIGMSGLEEELNEEGILHLGGTDSADNTLEPFDLSQFELDPDVGAVVAGLDTSINYTKLSKAFQYLTRNPGCHFIATNEDSTYPTSAGLLPGAGAIGAPLRYALGRDPISTGKPSSTMLDCVRAKVHFDPRRTIMVGDRLNTDILFGQQGGLATLLVLTGITSEEEISGPEPSPIVPDFVTQSLGDLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM13</accession>
    <name>A0A9P6EM13_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_848946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM13"/>
    <dbReference type="OrthoDB" id="3357408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="7834" checksum="535BE2C8CE155C07" modified="2023-09-13" version="1">MVLVTTLSLIIGAFNLSIGFYHNLQIFVLFRGRGDPKEAFANISDWINVAYTVTTLLQVLLGDAILIYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMM1</accession>
    <name>A0A9P6EMM1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_891537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMM1"/>
    <dbReference type="OrthoDB" id="3263055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="96"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="27067" checksum="B117D9B2247BA0CD" modified="2023-09-13" version="1">MGYLAYSYMVTRVGVDDGVQLIVRTVIGAATFTVQMYLIYRIWRLKFYKWLVVIDGFLSVAQLVVVIIFTVKAVPISSYEELRNLKWLAVTANILSIASDICIALSQISVLHRAGAFEYSRSKQVTQRIVLFTINNGLLTALCALGSMLSIILYPTTLVYIAFFFCTARVYGNTMMLSLNARGYFQGHPDDAVNVSDVSSLGNVNELSTPSGVTSESSRTSGNLATSSIEFAVEESSSSESCKSLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN10</accession>
    <name>A0A9P6EN10_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">TBP-associated factor 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_785561</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="308861at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd09839">
        <property type="entry name" value="M1_like_TAF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000011">
        <property type="entry name" value="Transcription initiation factor TFIID subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057345">
        <property type="entry name" value="Ig-like_TAF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037813">
        <property type="entry name" value="TAF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057991">
        <property type="entry name" value="TPR_TAF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15137">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15137:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25316">
        <property type="entry name" value="TAF2_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25577">
        <property type="entry name" value="TPR_TAF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="12">
        <location>
            <begin position="1261"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="12">
        <location>
            <begin position="1645"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="12">
        <location>
            <begin position="1755"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1154"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1408"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1848"/>
            <end position="1871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1182"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1408"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1429"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1490"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1588"/>
            <end position="1600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00076306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1871" mass="209704" checksum="A1CFFB1475B43848" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENL0</accession>
    <name>A0A9P6ENL0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_846869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENL0"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040456844" description="F-box domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="367" mass="41840" checksum="5499AEC37AC0F645" modified="2023-09-13" version="1">MLIYAIPTFAPLHCVMALSCSTNPSNWPGTWHGSRTAYFYRPRGVLHRAQGLAAPQNPSESKRKYEISRQQRRASNASTVESKSCDNAQSSGSVLSSFATTCLEVLLRRANDSDASLEGILDLPYDIVLEVCFALVYDIPMFSYPVGRPQIFGHLTPLDLLNISRTSHQLRNTLLDRRVRCVWQASFGNIPRLPPCPSDLNEVQYAALAFDDWCSFCLAPVVDQISWLCRQRPCPKCIKEQFIPQTELADWLPKDFCLDSPETLFPYLRRRGQRHYLRSTLKVYIDELNCLPGENREKSLSDWQERRKVVQAGKQTHAVNSDTWLIQWTAAQRSLSATSYLTEIGLVIALLFSLMYLWSEQLFPKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP28</accession>
    <name>A0A9P6EP28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_847618</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="47"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="279"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="426"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="702"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1001"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="438"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="478"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="715"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1346" mass="146090" checksum="602F6126A00F21E2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPY4</accession>
    <name>A0A9P6EPY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_757950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPY4"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="62"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="49694" checksum="9D2D03AEFB6886ED" modified="2023-09-13" version="1">MAELSGLPQSLQLVSDPKSRNKCIAKTYSQAGSLLFSEESFAAILLFKEKSYRCDTCFQRPSAISLKKCSGCGGYWYCNAECQTIHWKRGHKQLCRHFQAYSTSAEFRELQEHKKLDALLLSHTIARLSLLAQPYRPVTNTPGDILFSLLPHPSTGLAAPVICPVKPSPPSGLADLIYSRFGNNNFSIHSHFSSVGHGVFPTASRLFNHSCVPNAAAKYVWIPQKIVTMTAVALRDIQPGEEVCLITLPYLDPALVQTRPHILQISYGFVCDCPSCTDIRVVELPKVPSNPNDLTRIGKELREFVGVDASDAGVFSPPKLRDLPTGLRCVLREDYISFLSEVFSQSSHKGDHEIAIDSGMTLLALYLLIYPCNYPQIGMHLLELTKTTWNKRMSTRLTVAQDRSAKERVMRLLSSAQRVMEVYGPEGDVNGPWEEIDTLHKLLLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPZ9</accession>
    <name>A0A9P6EPZ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPZ9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="84" mass="9313" checksum="E3943C1FF097FFC0" modified="2023-09-13" version="1" fragment="single">MRLIVSTSMGRLPMISQMNIRRLLFAATWVGPQDALAALVSLPGVQLFFLSELPLLSHCFCGASLCINLNLNLLIFVLRLTLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQA4</accession>
    <name>A0A9P6EQA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GID complex catalytic subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glucose-induced degradation protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_846611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RMD5/GID2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQA4"/>
    <dbReference type="OrthoDB" id="1933281at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16652">
        <property type="entry name" value="dRING_Rmd5p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000143">
        <property type="entry name" value="Regulator of gluconeogenesis Rmd5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037683">
        <property type="entry name" value="Rmd5_dRing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="10">
        <location>
            <begin position="143"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="11">
        <location>
            <begin position="328"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="328"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00075398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00080744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="384" mass="43161" checksum="5AC384867D8AD6F3" modified="2023-09-13" version="1">MDASLKELTKLEKLTASNGKGPSIDQSIDSLLATLKEARASFVSGGCSAAYLKELAKSVEAKKKEIDDRQKEIYNVLSRLGKALDKKFPVALPSYPELFSTTTSVTALERTIALHLLRTGQFEVAEIFLSESNIKIPDELWKKFVDLHKILKALRNEDIQPALDWAQEHQKFLKSRNSPLEFYLHRSQYIRLLLKEHPPNPLPAIAYAKANLRPFYQEHPVEFQRLMSCMAYLPLSKLQSSMYSDLASPTLHFDLEPLFAKEYCAKLGMSRQLPLRVVGDIGGGGALARIEKGRKVLGDRKGDWNQMDELPIEIPLPPDNRYHSIFACLVSKELSTEANPPMMMNCGHVISKDSLQKLNKSGGRSKCPYCPIETPTGTAMRIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQG4</accession>
    <name>A0A9P6EQG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_756370</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 23">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQG4"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070936">
        <property type="term" value="P:protein K48-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16489">
        <property type="entry name" value="mRING-CH-C4HC2H_ZNRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051878">
        <property type="entry name" value="ZNRF_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="15" id="KW-0458">Lysosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0519">Myristate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="20">
        <location>
            <begin position="502"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="19">
        <location>
            <begin position="669"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="397"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="400"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="429"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9534176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="711" mass="79510" checksum="8428B7E252B36C88" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQL9</accession>
    <name>A0A9P6EQL9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-oxoisovalerate dehydrogenase subunit alpha</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_758465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BCKDHA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQL9"/>
    <dbReference type="OrthoDB" id="3845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000055">
        <property type="entry name" value="2-oxoisovalerate dehydrogenase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050771">
        <property type="entry name" value="Alpha-ketoacid_DH_E1_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="3">
        <location>
            <begin position="62"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="419" mass="46964" checksum="B6ADF3DF4D756299" modified="2023-09-13" version="1">MRRQEVLPTTASPIVSKLDFFNAVGNKPIPTFRLLDGVGKPLEGAVLPEVCIDKAFARRLYESMQMLPTLDNVLYNVQRQGKISFYMTAHGEEATIVGSAAALELDDEVLGQYREMGVLLWRGFSLDNVMAQCFGNEEDTSGKGRQMPVHFGSPEHHFHTISSPLATQIPQAAGVAYALRRDPKRRDRSVAACYFGEGAASEGDFHAGFMLASTIPSPVLYIARNNGFAISTPSTEQYNGDGIASRGPGYGIDTVRVDGNDILAVISAIREARRRCLQQGRAVLVEAMSYRVGHHSTSDDSFAYRARAEVEDRKRIDNPISRFRLFLESRGWWDNDAEADMKARHKADVMKAFKRAETMKRNELGELFTDVYGGEQPWNIREQREELSRLIEKYGDKWEPWKSELSKFKNGGKDLLKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQR5</accession>
    <name>A0A9P6EQR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_844108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQR5"/>
    <dbReference type="OrthoDB" id="6512918at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158:SF2">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="8"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="286" mass="32095" checksum="09FD69783B6038EA" modified="2023-09-13" version="1">MNPTDLAVSVANLTYQHNSFSPPSLLNVNLALPLGSRTLLIGANGAGKSTLLQLLAGRRLVTLADADVRVKGQDVFRNTPPGITFLGTEWAMNPVVRGDIVVSVFLDSVGGYRHKERRDKLLDLLDIDLDWHMHQISDGERRRVQLCFGLMVPWDVLLLDEVTVDLDVLVRDDLLKFLKADSEARGATILYATHIFDGLNDFPTHIAHMRNGEFVTNPTPWSTDSAVGSLSLTTTLLYQVALQWLKDDRDHRRELEKLGKKTRGARKDDAVPSDSETFYRKYDYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQV2</accession>
    <name>A0A9P6EQV2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein Arp4p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_866623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQV2"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="435" mass="47962" checksum="204FAFD9C43DFC65" modified="2023-09-13" version="1">MVNYGGDEVSAIVVDVGTSSLRAGYAGDDTPKSVIPTSFGFHKAQQTDPDVSMGDVQENGTTVVKSKYSSIYVGSSGPSLWREGMEIGNPIVEGLIQDYEPVKPLVDHAITKVMRANPAEHPILVTEPSWNTPANRERMAEIMFEEFNVPAFYIANTGVLNAFVAGKGSALVIDIGQAMASVTPVVDGFILRKGLSYSPLPKLIHAHARHVLLNPTQHRRGVELIPHQLIASKLPVDPGQPPNYTLRQDRLTGTTESWRKWAEEREVEEWVQSVAGVVDQGWNDQMVAQRPPRQYEFPTGYSAYFGMERFQVGEQLFNHGAALQASNPNLPKTIPALMTEALRACDPELRQVLVSNVVLTGGGSMFAGFAERLQNELVRSFPHTRIHAPGTPIERRYGAWLGGSILASLGTFHQLWISREEYQEHGKNIIGQRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES67</accession>
    <name>A0A9P6ES67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_757250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES67"/>
    <dbReference type="OrthoDB" id="10263073at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040166408" evidence="5">
        <location>
            <begin position="20"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="120"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="298"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="458" mass="48946" checksum="DF231DCEE3B13277" modified="2023-09-13" version="1">MISVASCYLALLLSSTAFAAPVADLFDAASLSSSATPASVLAPSSTSSAASSTATVPYISLNPNFPMWGPNDPTTPEAERGTLGASVIGPTDTDTVLQNPDLLAPPTTDGGSVPNAKWPYSLSSNRLQTGGWARQQNVNVMPFAENLAGVNMRLEAGAIRELHWHKTAEWAYILQGTTQVTSVNADGQNYVANVGAGDLWYFPPGVPHSLQATNDDPAGTEFLLVFPTGDFNEDDTFLLTDWMAHVPAEVLAKNFQTDISTFSQVPAKELYIFPSNSPAPPSDAPISPNGVVPQPFTFNFSSVAPISVPGGTYKIVDSTTFNISTQVAAAEITLEPGAMRELHWHPTQDEWGFFLEGTARVTIFASSGNARTFDYQAGDISYVPATYGHYVENTGNSTLKFLEIFNTDKFADIGLSNWLALIPPALVQAHLGFNETTINSLPKTKRVLTAPYNVTLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESZ0</accession>
    <name>A0A9P6ESZ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_844008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESZ0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="9662" checksum="E6DF1420C2127316" modified="2023-09-13" version="1" fragment="single">MSSKVVSSRDHRRVRDVLQLCLLINFGGVLVFGGGGGGVGGDSGVLVVFAIRALKLLSTRTLGSHALLSSTSSAISSSRLSLSALLFLRFDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU98</accession>
    <name>A0A9P6EU98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_223504</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU98"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040214016" evidence="9">
        <location>
            <begin position="19"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="10">
        <location>
            <begin position="159"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9534958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="286" mass="30346" checksum="A844D1ECCF2D2A64" modified="2023-09-13" version="1">MFHSTFFVLFVAISAVIGTPLTSNIERRVCGTTPSDSEVAAKEAHFQAHQVPARMLSAEAATIPIYWHVVYGSTNLTDGYIPDSQIAAQIDVMNKAYAPAKITWTLAGTDRTLNSDWFNNAGPDSTQQDAMKKALRKGGVNALNVYSVGFTSGSGQGLLGYATFPDEYQSAPSDDGVVMLYSSVPGGTTVPYDLGQTLTHEAGHWVGLYHTFQGGCTGAGDSVDDTPAEASPAFGCPAGRDTCTGGGVDPIHNFMDYTDDACMTEFTPGQVARLQSQIATYRSITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIB3</accession>
    <name>A0A9P6JIB3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_872063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157956">
        <property type="protein sequence ID" value="KAF9522196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIB3"/>
    <dbReference type="OrthoDB" id="2576233at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="958" mass="108283" checksum="4F259EA5AAA82192" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIQ7</accession>
    <name>A0A9P6JIQ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIQ7"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="59992" checksum="7759151D8395B163" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ24</accession>
    <name>A0A9P6JJ24_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_863900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157932">
        <property type="protein sequence ID" value="KAF9522842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ24"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="5">
        <location>
            <begin position="70"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="29193" checksum="59A4947221761D3D" modified="2023-09-13" version="1">MGEEETKKSPESISEDLYKNLIHYFKFASSAYATVCPRPNGKKLITPVSNPGTDVGGFIARDDDRKEIIVSLKGSASITGAVLDAQVLLVPFLCPGCKLPSGIRVHSGFLAAWDSIVAEVAPIVEYQLSSHEGYGLITVGHSLGGSIALLAAVHFKEKHSDYSIKTYSYGAPRTGNKWFADYVNSQFGENAFRVVHGNDGVPTIIPMSLGYHHHGIEYWQREDPSCGKTTVKCDANGEDTTCSASIRSQGINSAHWEYFGILATTPFCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJE1</accession>
    <name>A0A9P6JJE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">beta-glucosidase</fullName>
            <ecNumber evidence="3 6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_871819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 6"/>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJE1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="7">
        <location>
            <begin position="407"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="864" mass="94895" checksum="5973E43BF64D6710" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJR2</accession>
    <name>A0A9P6JJR2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Transfer RNA methyltransferase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TRM8</name>
        <name evidence="10" type="ORF">CPB83DRAFT_821359</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with TRM82.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="9"/>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJR2"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="239"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="30015" checksum="0F73BD6F7BA97D62" modified="2023-09-13" version="1">MAKRKRAEEQLQESRQSVILPQKRHYRQRAHANPFSDHTLQYPSSPEAVDWTLHFPGFAGLAKSPQFADVGCGFGGLMIALAPLFPNTLILGKHGFTRSLRMEIRVQVSQYVQDRITALRISSAEPQSFQNVSVVRANAMKFLPNYFAKQSLSALFFLFPDPHFKIRKHKARIISPTLLAEYAYVLRPGGIVYTITDVKDLHEWMAAHIKAFPLFEFIDEETLRKEGQGPIIDAVCTATEEGKKVERNGGEKWLACFRRITDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK20</accession>
    <name>A0A9P6JK20_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_740229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK20"/>
    <dbReference type="OrthoDB" id="5598396at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="6698" checksum="8E1E291C8836BCEE" modified="2023-09-13" version="1" fragment="single">RSWFDGKFFALLDRSFGGHSLRAGGATFYASIGLSEDIIQALGRWSSASWKIYIRDNPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK45</accession>
    <name>A0A9P6JK45_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AN1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_951338</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK45"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057357">
        <property type="entry name" value="Znf-C2H2_ZFAND2A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF40">
        <property type="entry name" value="CDC48-ASSOCIATED UBIQUITIN-LIKE_ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25403">
        <property type="entry name" value="zf-C2H2_ZFAND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="103"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="29027" checksum="8F5CAEFF9D55D47B" modified="2023-09-13" version="1">MSTTSQRDAELLAVGKQCSHSSCNLVDFLPFKCHHCQDSFCQEHFKVDDHKCPKYDESQHNRVAPNCPLCNIPIAFRQGQDPNVRMDQHLETECSVTTGRVKSKSTPVCARPTCKKVLFSPIRCDKCRQQFCPAHRFPGDHTCASQTASSTAQSNMYSRFEATSKGLAAKASAAASSAASSAAKKSPTTAKPIAKASSAPAAGSSTTSNAGPKLPFAKMKTNSRAKAERESRLKAMRARAQKGLLSDEQLVILEAEEAAAKDGKDCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK83</accession>
    <name>A0A9P6JK83_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_820710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9523997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK83"/>
    <dbReference type="OrthoDB" id="10027144at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22448">
        <property type="entry name" value="KH-I_ScSCP160_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22450">
        <property type="entry name" value="KH-I_ScSCP160_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="155"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="324"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="467"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="552"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="633"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="719"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="802"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="877"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="958"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="1154"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1083"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1083"/>
            <end position="1099"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1229" mass="132568" checksum="13A70EA9EF3E00AF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLH1</accession>
    <name>A0A9P6JLH1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1688-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLH1"/>
    <dbReference type="OrthoDB" id="2153176at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48079" checksum="0D952413320B2D63" modified="2023-09-13" version="1">MNIAGIIPPFQTATYLRTLPSIRERCGRVHDLAKDGKLKFFDYHPEKEIDVAKFCIAIMKRDYGENFTAINPHGRWRHLDASIDRVQPMIEKWSSLPNPPDLKEQARRTIDLFVVSVLLDAGAGNLWKYKEAVSGLSFTRSEGLGVASVHMFEDGLFSSVEGQPYQVDANGLEKITAEKVAKAMQVNESNPMVGIEGRSSLLYNLSKALRTSPEFFGSAGRPGHIIDFLEDESKLEGETRQVPLAALWIALLDGLNPIWPSRLSLGGVALGDVWPCPALKASLKNPAEGDDLVPFHKLTMWLTYSLVEVLEKNLRWKIIGLEDMTGLPEYRNGGLLVDHGVLTLKENALPQDPNSGLPHAIPSHPAIVEWRAMTVIELDRIAELIRKELGLKASGLTLAQVLESATWKGGREIAKLKRPETGGPPIEIESDGTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLU0</accession>
    <name>A0A9P6JLU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLU0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="253" mass="29168" checksum="E6C6305ED237BDDD" modified="2023-09-13" version="1">MPHLSLRRAAEKRSDSALGKLLKSKQKFFKSKKKMLRDQKFSRLAKDTILPLLPGVSTLAISLSSGHHSDPSQKRDSDRRETEEKEKREREKREREREKREREKREREERENKKRKEEAARIRRQLMKQRNLLFAAMLGGYIHQNLRSLLLAALLLALFLELLGWFILTGLFVTFLIYLLLIIHTPSKSTSGIKQLQYSGPSPTPMSGARRPLGQCMWVSKHQFGIKPRPGPSIRNSASPPPPQLVNIFSAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLW0</accession>
    <name>A0A9P6JLW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLW0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="104" mass="11566" checksum="E500F036B57919E8" modified="2023-09-13" version="1">MIPESNSIKLLLIRHYSTWHGDSRYLLRVGYVSTRKASSIIPSNCNKHYLHTSFHDPIHRPIHNLSACPTSIGLCLLTSGGLYVIANFSCPDPAQSPNFSGMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JME9</accession>
    <name>A0A9P6JME9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Terpene synthase</fullName>
            <ecNumber evidence="6">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_771756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the terpene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JME9"/>
    <dbReference type="OrthoDB" id="6486656at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="361" mass="41400" checksum="20C6687372444773" modified="2023-09-13" version="1">MPVSTNGTFERFYIPDTLANWPWPRAINPAYEDCKISSSAWCEKYGAFSSRAQKAFNLCDFNLLASLAYAHLPPDVNRVGCDLMNLFFVVDEHTDAMDPRSVQDWVNIVIDALHNPHKPRPEGEPIVGEVARTFWENGMKCLGPSAQHRFVETFATYLQNVVTQAQDRDKHLFRDVISYMDVRRETIGAKPSFALLEHDMELPEDVFNHPLLENLRTWAIDMLILGNDLCSYNVEQSRGDDTHNIVTLAMKQEDTNIHGALAFVSDMHDRLADQFISNYQHMPSFGEPIDEWVSRYIEGLGNWVRANDSWSFESWRYFKGDGLRVQKERWVDLLPPAPKDELTSSSKLALLSLTELEVNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN10</accession>
    <name>A0A9P6JN10_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_456301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN10"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="109" mass="12932" checksum="50D751BCA314960C" modified="2023-09-13" version="1">MSFLTKLFSKTQRSDSHALQYNSLLAQYHFNTNDAVFLAWRRNWPHQHRFKIHRQDPTDFRLTLHWDHSPHPFILQIISTFPISRLKMLSLFAPVDREILLATFGNLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNX9</accession>
    <name>A0A9P6JNX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_856712</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNX9"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="5">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="22604" checksum="172A1AB07BD0F55A" modified="2023-09-13" version="1">MVNLRSQKRLAASVAGVGKRKIWLDPAEQAEIGNANSRTHVKKLIKDGRVIIKPTTVHSRARTRDLLAAKRKGRHTGYGKRKGTAEARMPTKVQWMRRQRVLRRLLRKYREAGKIDKHLYHILYQKSKGNVFKNKRVLMEYIHKAKAEKNRTKVLSDQMEARRVKNKATRERRAARIAEKRQGITAVEHENTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP98</accession>
    <name>A0A9P6JP98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metallopeptidase family M24-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_856461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP98"/>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="540" mass="59534" checksum="FF3B7BF6490A1F1B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPJ1</accession>
    <name>A0A9P6JPJ1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_894357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3064439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="816"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="712"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="751"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1290"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1363"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="599"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="751"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1373"/>
            <end position="1388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1742" mass="193685" checksum="4B0E89066DB12E8F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPK8</accession>
    <name>A0A9P6JPK8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_855413</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPK8"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="509" mass="56371" checksum="9A5A92C8907F3EBD" modified="2023-09-13" version="1">MYRILVATFVCGPFTMAIFRILMGAVLSLTTAVSAISQISLDNAFLSYDDGLFSPVDDLSVLAEDRFTMLSHPSFPHYSVRMKKSSDFCDDSVKSYTGYIDIESRHIFFYFFESRNDPDKDDVIFWTNGGPGCSSSLGLFMELGPCRIMDGNGTKYHPESWNSNANVFFVDQPIGVGFSYADYGETVSTTEEAAKDIAAFVAIFFENFSQFKGRSFHMAGESYGGRYVPVFAAAVYDQNSKLVEAGCTPINLKSIMIGNGVTDFASLYDGYYQMTCTGASVPPFLDIQSCVDMKLSLPRCQAWLQSSCIEQFDKINCGAATMFCDAAFNVPFFSAGKNPYDLTQDCSQEELRETLCYPALGHIAKYLSSDKVRAQLGVDPVVPQNFSACSLDVGMSFSLSMDMAQPTYLYVAQLLERGVKALIYVGANDWICNWVGNEAWTLALEWSGQDYFIDLPLRDWQVEGIVAGRTRSAGGLTFATITGAGHMVPYDKPKESLQLVQRWLSESEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPV4</accession>
    <name>A0A9P6JPV4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPV4"/>
    <dbReference type="OrthoDB" id="3047760at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="263" mass="29842" checksum="7DCAF6C02F643121" modified="2023-09-13" version="1">MAAQLRYFQNIPTIHDKHPEIPPFYHGLNLNQALQVDDVYSLEDLQQARATASALKGLHLAGVAPEVNAEIIHTAETRSATIEAAHSVLKFSAPNFQQMAELLIRIDNQLVEANQRMVRIEQQAERMDQRMARMERKVDVIETNTSRLPAQITNLRIIGRNNRLQGAVELDAPQKEVPGSGRALALRMAPNQDVRRQLEDEYPPNHPAALLGSSPPEFIVDPENYQHIDILKLILFYNDRFGVLVTDTLPTRMIKLRTFLTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ38</accession>
    <name>A0A9P6JQ38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_852822</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ38"/>
    <dbReference type="OrthoDB" id="5570009at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="219"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="534"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="774"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="846" mass="94813" checksum="87151FE0567B2550" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ50</accession>
    <name>A0A9P6JQ50_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_835841</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ50"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="40901" checksum="E52E0D6425C2B8EB" modified="2023-09-13" version="1">MLEKEAMKKLFREVKPDPVTGQLNDTDIIQYINAHPNDPMRGAIWLVSLDYFGLTTEERWGDNWDTGDQETTHGKKRAEERGGAPGQSFQLTCKIREGPEVLGIGDDDVRKVSVFLGLPTWNEIEEFTFFNQFKPPFTWIFETDQIRDNIGEKDLKRANESFRKYMKYSEDLKERGNKAFAGGRREEAVAKFQDAAENLDKLLLKKISEPHEKEAQTRLLLAICLSNCSAAIMLVVDGQKDVDGSIKDAERAIIADATCPKSYNRLSRAYEEQGNIFEAQRALARGLCVKKLENHYGLADHFILLRTQEKGLKAMGKEEYESWWNLTFVEDKRMADLMDGLEGSWKKRLEDRRAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR64</accession>
    <name>A0A9P6JR64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_180820</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR64"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00598">
        <property type="entry name" value="GH18_chitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040242055" description="chitinase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="49"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9530432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="35162" checksum="0CFDFA91318154EE" modified="2023-09-13" version="1">MKSISLWLLAVSAFNAFQAFAAPSNVPTIGKSANKNITTHGVQAAPAAPHWVVYADSYDGTTGPPAASALQGYNVFNLAFLLLEGAWDKAYEWTSLTDAQRSSVKSQYAAAGIKLVVSVFGSTDVPTSSGVDPIATANTMAAWVKKYNLDGIDVDYEDFNAFNAADGSAENWLISFTKQLRTQLPQGQYILTHAPVAPWFSPVSFGKGGGYLKVHQQVGSLIDWYNIQFYNQGASEYTTCANLLTTSSNTWPQTAVFQIAANGVPLDKIVIGKPATASDSTNGFVSTSTLASCLSQAKAKNWNGGAMAWQYSHAPSSWIKSVRASSWAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR95</accession>
    <name>A0A9P6JR95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_752667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR95"/>
    <dbReference type="OrthoDB" id="3247268at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="18302" checksum="082F925B74C425CA" modified="2023-09-13" version="1" fragment="single">MSSETLDRSLSSLSIHSSGSMPEDDWDPLESQNSVAAPQFPTLTPRNSIIFPAEDTPGRKTRYHSREGSLQNGNFEGRGSGKRTLSELLRLHSEKTSNGEFSQEEASRIADVLGQWINASSSPYEGEDDFFSRHSQDDINLNAARRILGVQGDFGRPRGRSESANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRB2</accession>
    <name>A0A9P6JRB2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_762971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRB2"/>
    <dbReference type="OrthoDB" id="3261222at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40215" checksum="E9E97A7615910646" modified="2023-09-13" version="1" fragment="single">MGFAFVDDVAISVKRKDFKETHRKLKRMMEKEGGVLEWAETHNCTFGIEKFQLLDASRKLRDDPAGGGKKVPIERPVLKIRGQHITPAHSIKFLGVHINQELRWKAQGAAAIARGAGWLAQYRRIAKPTSGVAHRHMRKLYLGIAIPRMMYAADIFLTLERQSANGKRPGGAMRNKLASLHGRIANLIVGGMSSSPYDAALAHANILPFHLLVDKVRHSAAIRLATLPITHPLHIPVKEAVSNYASTHQTPLHELMKTFNIKPDRIEKILAVRYNARWVSSATTSIAKSREAALEEEKRREGDKWRIYTDRSGIEGKIGAAAVLYQNNEVKRTLRYKLGSSRLHTVFKGEGVGILLGLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRN7</accession>
    <name>A0A9P6JRN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_763297</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRN7"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034737">
        <property type="term" value="F:ergosterol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008204">
        <property type="term" value="P:ergosterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF9">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9530446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="612" mass="69273" checksum="AADD40127F1E19EA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRP3</accession>
    <name>A0A9P6JRP3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_811692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRP3"/>
    <dbReference type="OrthoDB" id="3357408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="341" mass="38392" checksum="70F0E422C425B3E7" modified="2023-09-13" version="1">MAQQSFPIDEAQLVGLFMQSIFYGTLLWGDGWFKPVRLVHKTMLLATTLMFIIATLDVAFQFRHNLEAFIYFKGDPIDEFNKTSYWLNVVVMGCYVAQVFVGDAVLLYRCWIVYQKNWVVITLPITLWLATTACGITTIYNEATMDTTGKLLNSKIFLPFITSMLCLTLATNVLTTTSRRFPHSIICLDVALIVLRIWGIRQNLTGIYTPHYPLTNLLVVLIESGLMYTLSIVVLFGVYMASNNAQYGVSDAVVQIIGITFNLVITSVHRKESSNRCTIHPIHSHPTQPSGSLPMHNIISIHTTVDRFPDQDLPQKRISSDENQSTPTDTKVTLTKSEGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSB7</accession>
    <name>A0A9P6JSB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_810496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSB7"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="132"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="448" mass="49785" checksum="642F7EFB3FB69321" modified="2023-09-13" version="1">MASPAKSSEWPPKLRTVLPIFPPPEPLQQPTLPSPPRKPAFSVPYTLSTHLVPATYLRTTKPVPIPDYTFLPSATKAEKKRIVLQTTQTLFKLRGELGRQSDGHPQALWNCLNRYVRHDLKEANDRTGITLFLAHANGFPKEIWEPMLDRLLSSQAGKIIEEVWAWEAVQHGDAGLINAASASGTFDWSDNARDIVNFLSNFLPTRATNGDLPTRLTRVPEREVKERLEAGFHRRRVVFVGHSLGGTSLSFAACLYPALCTSLVLIDPIILETPTEVESGAGRKGIQMMIGGAISRRNEWPSREAVLTGFLESPFFRAWDPSVLKVYIECATYTTPSGTTKLKMPGILEAIVFADFYTAMEVFRHFHTLDKNIPLRCILPGKDEAMGIPGGSVKWVELRPTNSTNVKIPGTGHLIPHEAPRELADDLAEYLLQSFHLADSSDIVKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSK1</accession>
    <name>A0A9P6JSK1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_892575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSK1"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="51"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="648" mass="74223" checksum="B3BDD2DC0C341193" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSQ7</accession>
    <name>A0A9P6JSQ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_762493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSQ7"/>
    <dbReference type="OrthoDB" id="3141838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="29708" checksum="574CDC60407ED54D" modified="2023-09-13" version="1">MSIVDRHQSPVTWQTHNRHPALHQLLQSSSPAPPGSGAGTPSIAAVTAGSQPSRHYYGSSYGSGARPPSTSVYDAPVPAKNERELTRETLREILDYFSQLVPRHFGPNRPIRLVVHGGACMLLHEGIYKLSVQQQQMSPHLPRRTTTRDVDYIHRSFVTEMTSMGVPDAASRLAECVKAIARRFGLGLDWMNSDADIALPYAYDPQGKPYDPIYHASIQANNIDLHTIYTSPNKLLTLISVTPFWAVSLKLVRYVKWDPGDICLLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT78</accession>
    <name>A0A9P6JT78_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_582614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT78"/>
    <dbReference type="OrthoDB" id="2927236at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="353" mass="40138" checksum="65E6F10DFADF2002" modified="2023-09-13" version="1">MEGLDLRNNPAANSTISIFSLPHIEQITSLSFKLSHSLFKSIISHVGDRQLGSLTVLRLNVLEAFFQDLLDFLTFCPNLKKLYILQTFDQNFPPPMAFSSAALQSLEEFMGPMTLAEVIVPGRPIHTIHLFDHLIRLEHDPDYKSDFSLEDLKILGDSSAHITTLSISISEQLASKQGMEFIARFFPHLRSLELVTEIVFGFQECQPEVVADKDRPINTLGLPLVEPMDEADKLGTQVYVQNLLESVDYGYEVLIYGVALGKYPLPNKIKRLNIRPAHFGSDEPGRDSPDVMFFKPFTFSMMRRIVDALSTRYLDLANVKLGYHTNKWRLGWEKSDEGSWLLVEMPKDLNRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTT0</accession>
    <name>A0A9P6JTT0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thc1 RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTT0"/>
    <dbReference type="OrthoDB" id="5418203at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053800">
        <property type="entry name" value="Thc1_RRM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22877">
        <property type="entry name" value="RRM_Thc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thc1 RRM" evidence="2">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="28200" checksum="99C9ADCC0AA00752" modified="2023-09-13" version="1">MAAALSGLSACVTRILYLTGFPKELKTKDIQSAFADYDNVAGGFKIKWRDDTSLLIVFQDANVAKRAYLTTLAFPPKVLTSASGVAATIKPYDGPDAQSVIQTVNSRGQHHTTASRSHQPRAASVSVFPNTRTASGSIAIPNALRNGFGGAPGSQHVALPERQEGREPSPTLPSLPSHPTLDALINSSLPHSNILPTDPAILSSSMQHHQAQHEVSGGPRIGDPGKRMLGAALGVRHPGLSQRMVSGGSSPGNGMEHVQRAMGGLIVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTX1</accession>
    <name>A0A9P6JTX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L32e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_49330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTX1"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="126" mass="14581" checksum="88FF53B653A04DC1" modified="2023-09-13" version="1">MAIKIVKKRTTKFKRHQSDRYHSVKEAWRKPKGIDNRVRRRFKGQTPMPKIGYGSNKKTRHLLPNGLKKFLVNNIREVDLLLMHNKTFAAEIAHNVSSRNRIAIIGRAKALGIKVTNAEGRLRSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUE7</accession>
    <name>A0A9P6JUE7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUE7"/>
    <dbReference type="OrthoDB" id="3237291at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="977"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="722"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="801"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="997" mass="105864" checksum="66F0842C9573D9E5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUV6</accession>
    <name>A0A9P6JUV6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Elongator complex protein 3</fullName>
            <ecNumber evidence="15">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_846534</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="15 16">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="15"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUV6"/>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106261">
        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000003">
        <property type="entry name" value="Elongator complex protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15 16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="83"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="398"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR005669-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9532880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="62295" checksum="C70D9103B2D52A67" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV02</accession>
    <name>A0A9P6JV02_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-demethoxyubiquinone hydroxylase, mitochondrial</fullName>
            <shortName evidence="8">DMQ hydroxylase</shortName>
            <ecNumber evidence="8">1.14.99.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ubiquinone biosynthesis monooxygenase COQ7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ7</name>
        <name evidence="10" type="ORF">CPB83DRAFT_845105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + AH2 + O2 = a 3-demethylubiquinol + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:50908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="1.14.99.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="8">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the COQ7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.60" evidence="8"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV02"/>
    <dbReference type="OrthoDB" id="275371at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008682">
        <property type="term" value="F:3-demethoxyubiquinol 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01658">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237:SF4">
        <property type="entry name" value="5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="COENZYME Q10 BIOSYNTHESIS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9533344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="24191" checksum="3455E7C7EDC58D77" modified="2023-09-13" version="1">MILRLAPSLSRTFTTAARRTPSSLYTKVSQNSRATTSTPSDLTDTEREVLEGALRVDQAGEIAANYIYMGQKAVLGRDKELGELIQDMWDQEKKHLLVMDKLQVQHNVRPTALSEVAKVAGFALGAVTGLMGKEAAMACTEAVETVIGEHYDDQLKDLATFSSNHESLPLLQDVIQEFRDDELEHLDIAVDNFSHQAPAHALLSSLVGAGCKVAIEVCKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBQ4</accession>
    <name>A0A9P6BBQ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158052">
        <property type="protein sequence ID" value="KAF9521473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBQ4"/>
    <dbReference type="OrthoDB" id="2856616at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="49132" checksum="B4A6CC85F75B5FE1" modified="2023-09-13" version="1">MSKAFVALSGMHPIPDDVLWHVLCQNTPSNRHFYSAQHDDLYAASGCMETARFTSQVCRRWRRIMLSSTTIWSKIIDLSCLDGYTQPDQWLSEVIGKRTQGQNLHVYGQQWDFGFSLKLYDSGAVQVIIFLSRAQGLLQGFESILGENGPQWLRINSENPKPQAPIYKNLRVLSLSSPTVGNNHDEHVESEHKTFPCAPLLEVLAVEQRVLLESPLPLQYRNLPTLSLSHLWSLKVEVDLSVCLATLLHVLPSTKCAVDMSIWTFFHDEYPVTWLAAFEEIIWSHYSKKIITGEENLSHHFKPLSSFAKFTGHVEWFILVLLDEMDGLEVVFRDRVQKRRVEVAGAGWLRAIIVDATRITRQRCISLVEGSIRTIDRTLSLIFGDGVSPDPGDRPVGRRSFQRPVGVAVKPPDEPFARAKLVQSVDPSFGVFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBW2</accession>
    <name>A0A9P6BBW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_778915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158129">
        <property type="protein sequence ID" value="KAF9521321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBW2"/>
    <dbReference type="OrthoDB" id="2678913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="8717" checksum="3626DCBC8D472F9B" modified="2023-09-13" version="1" fragment="single">MLVSTITHRRPFFFANHASSKIDPAFISNYITSEQIAGRYSQAYHPSHLESIIGPFRTSPLGLVPKPHSDSFRMIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC69</accession>
    <name>A0A9P6BC69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_928297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158079">
        <property type="protein sequence ID" value="KAF9521402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC69"/>
    <dbReference type="OrthoDB" id="3359887at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="502" mass="56650" checksum="57F139027001141A" modified="2023-09-13" version="1" fragment="single">MALIGDRFSRILAAKAPSGKTLYYPLAAPQNEVYNPGRPACYDTKDLPMRTQESYWETIAELEKATTKKDQSDITRRTGVSRLPLCAASPAFLHPTFFPIDPFHLFYENCTAFLWDTMTAPKDSQDQIHFSKSAQMGALIPLAMETLPPSFCGPVRDVHLKRNSQFKIYEWMAVLHWYFIPIAIELALNSIVLSTFAQFVEIIDFAMTIKPRSEKDLEYLHDLITQFLTNYERLFVANDPAKLHHARLCIFQLIHVPIHIQWNGSIRLGSQATVERAIGEAAHKIRSKKAPFSNLESIIYRRELFKILILYYPDLLPASFKSSPKNSSKPMQAHRIAWTKLAADSTLSTDLDLLSLYIGLDIRQKSTKTTVLRWGKFRLPNGNVLQSSLSKEGMANGNLIFGHAWAFYTISTDSTSPPRTLAIYTPLISVTTTSRIPRGKWAVGQLAVVEVAKIRSLVGIWTGVNTKGVYILRKHPGLDYLATDERGVEAGDLVEDEDQDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC80</accession>
    <name>A0A9P6BC80_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158075">
        <property type="protein sequence ID" value="KAF9521414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC80"/>
    <dbReference type="OrthoDB" id="3061861at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16564" checksum="D2085DC6B9B6B884" modified="2023-09-13" version="1">MECLAIAAGYVCLLQVAHNKNCADTPPAGGYLWGLEACPIMMPRAGYDKIIAGDRPGPNKNKQKAEHLRTFAVPARLIQDSSTTQTNRTINVFCAFVDDSIAIFMIDFACLWVARIGSQHQNRASNLEARKPKARTEKFRTPKKLLTNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2I3</accession>
    <name>A0A9P6E2I3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_739943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158142">
        <property type="protein sequence ID" value="KAF9521304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2I3"/>
    <dbReference type="OrthoDB" id="3265433at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="145" mass="16583" checksum="B0A7FCB7C8805903" modified="2023-09-13" version="1" fragment="single">SFHSRAYRRCRAALERLITSEDLGSWPELLPEHVKGSTAVRQPNIPGSTEVRLSWIWHHDGSLSEEPASGTAEYKRVHWLRGRAESQRWAEEVVLLEHEMQWTVQSYLYDASRWDHLAIISASRPGSAAFAFRKAAEWRTLAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2U5</accession>
    <name>A0A9P6E2U5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_841298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158084">
        <property type="protein sequence ID" value="KAF9521395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2U5"/>
    <dbReference type="OrthoDB" id="2790754at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="205"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="53002" checksum="F4DE43875C75F742" modified="2023-09-13" version="1">MLVEKNVKNGRHKLATLASREEDSHMGEGGANSGDEQDGPTVGQKRQRALSGRQSTSSGDEDNGGLANAPNQSQLREPGSEPPSPQPSRTGSPRRSQGTRRSQTPADDEEEEEPRHRSRQRLFQSDEEDEENNDEEEGRAINFGYGGDDEDEDDEDEDMFGGKEVVVTKGKKKSKKAKGGDNFDGSKVVEQDFPSQVLPLAKQCKAFFRKQASFGSAFPPRGLLERESYILNLLMDAANDDKDNSAMFVDLLKQISKQYPTLYCQLATFAIYGKRQLLNSLIGKAQQIVEMYFGLPGDLDPPIIRSRVVFLLEKSVFRYGGVDLKDKTYDAHAPCATPLVSNVVRAQWFDGTKGDRPAYWEIIKRKSIPKETLVLCFTVIECILKCWQGGTFTRVHFSEDNCSSRYQFFLETWDHLESNAPDYAKKILSENYDRTLKQTKNASLLFNEGDVAQDCEGINFTTLNEKAAEGALIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2V0</accession>
    <name>A0A9P6E2V0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_823547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158052">
        <property type="protein sequence ID" value="KAF9521470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2V0"/>
    <dbReference type="OrthoDB" id="3261436at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="32"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="881"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="912" mass="104753" checksum="B7E1DE82868ED52D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E333</accession>
    <name>A0A9P6E333_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158015">
        <property type="protein sequence ID" value="KAF9521610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E333"/>
    <dbReference type="OrthoDB" id="3261690at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="571" mass="65084" checksum="C1EA748C2F063A8E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3L8</accession>
    <name>A0A9P6E3L8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157974">
        <property type="protein sequence ID" value="KAF9521921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3L8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="47090" checksum="44DEBA7B1D9CBA10" modified="2023-09-13" version="1">MPPIPNELIAEISSYANVETAFAWLFVNKVEYPHRRRQLWTHQNHIRPLLNLLPKKKWINMNRYTDKPSSPQWHSNHKCKQCKGLKGKRLAPDASIDDETKQLLISLGGQMRELIVPCARDCPFIIDIVKGSIGFLRGQFEAPLLNVTSFKTARSGHDFGEVVRTKYDMDVYETLLDLCRVDRCKRIDIPDGMRSMQQLASAQTNLEQLHVTNPNPQLELWEHCTFWDNLTTLHLTEHKATLCDLFEDISPLRSLESFKFHCVDSGYTFEQPIATHVWPNLKMLTLYTSGFVMETFLETFNAPSLEKIVLRSSNFVSGATIAVMFKASARLTHIGVCRARSGFTFGHDRNIALTDDQIQPLFTMSTLQRLQLDRVFTSTVTEEVIQSLKALNDSTLIEYNNLRGVVLPYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E571</accession>
    <name>A0A9P6E571_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_776670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E571"/>
    <dbReference type="OrthoDB" id="3232986at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="21230" checksum="8ED7ECD37E5D8EEB" modified="2023-09-13" version="1" fragment="single">MDVDSLPLDTGIENEHLEHEHLEPLIPQTTTESPFYRINFPSCSDISSVKGQAPTFMELFNQDEHAQKRVKNPYYPYASQKEWELVRFLLTCGLSVAAINEFLGLDIEIGLSFRTAKDLRSHAEILPAGPRWTSKPMSTTTPTKKPTTLYHRNPLECMESLMRSPLLGDNISFGPYQLFASAARLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E594</accession>
    <name>A0A9P6E594_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E594"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="14971" checksum="D263B8537219BCAB" modified="2023-09-13" version="1">MSDLVVRRGASGPLHLTVDLVACVKPYGYWQSLCVDDLVVHHEALTIFIFVRYGAYFFVALICDSTLYACIYLQDNPSPTLRMHSPSLLESQPNAAKEPNSSQPSPTLANPRAQHDPTQPFRAQGFNPTSTKRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5W2</accession>
    <name>A0A9P6E5W2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_910834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5W2"/>
    <dbReference type="OrthoDB" id="3227921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="585" mass="65812" checksum="EC44F3AE751EA783" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E647</accession>
    <name>A0A9P6E647_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157923">
        <property type="protein sequence ID" value="KAF9523195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E647"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="478" mass="53740" checksum="6BC2E2514DCAE4D3" modified="2023-09-13" version="1" fragment="single">MSVQTHIDAAFQFRRIKPYQPGSGTSLEGTFSDYTQNAVSHGVHFKELNWTFDSSRTFQSLLQLELDPNKWRSIEETVDVDGVDNLYNHYQQLRTFSLGMASDSDSGHERFVESNVKIVLEYVGLLLQAAMVQIVNDAGSLEDEAEFRQFLQYIQSLTIESRSTIDGQPLAIPDMLIKLDGVLLGTFELKGTRFNHRPGTSSPTILAEWMSNRKDVIGPITSTSTQEAFAWSIVAQLAAQALLNRSKMGFFTTLIGTLRIYRYQLPSAPGKPGTFWVTPNLGPDDNVQNRSDRKTLVSFTRYVLAYIYMLLLDDPTIRDYLSVNKAWNMDEMFAEAQGANPAGADQDFYLRFSRYRRRMMSDIILATPYSPPIGRILPFTSSAEVLERFGESWSDRPDRCSTHLFFIPFPIAVMVLGGQVLMSPNRGLVFKFCSSFRHIVKLQCDDSILRGNAYNVAIVIEGGNVPPSTTQIGNTTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E728</accession>
    <name>A0A9P6E728_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="1 6">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_839492</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 6">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="1 6"/>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E728"/>
    <dbReference type="OrthoDB" id="5831190at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9523746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="23885" checksum="9B5C063C1484793E" modified="2023-09-13" version="1">MWLNSVRFKPPKLLTSLPAYQTLQSIYTTQKSTPTLTLRSLFDKDPQRFEKLSRAYESTYGPPTQLLVDLSKNLINDDVLKALLQLAKEAGVEEQRDRMFAGEHINTSEDRAVLHTALRTKVFEGNRPSTSVMFPLMTPSTLGALISMYEHKIFTQGVVWGVNLFDQMGVELGKVLAKNILKQLGKPEDVKDMIVRLVKFYWQLALGFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E732</accession>
    <name>A0A9P6E732_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_910477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157912">
        <property type="protein sequence ID" value="KAF9523680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E732"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="467" mass="50203" checksum="402F29E64BEE2219" modified="2023-09-13" version="1">MQPSQINISLPVISIQPSFPEVLQEIQDGVIPFDKFWVSCYKSGETSTHAKVLAELDETDRNLVLLKPVNEDGERDDDSVQIEGENGVSTVGCTKMGIPSTRVLSSKQNYHDNERSTSTRPQRITGFDVAPDSSRFATGYLDGSVYLYPTSSYTSTSTSHLPQSIDVTNKKTISKPHLSTVTSLKFFPSSRVLLCSGQDFSLSILPAGLPDDSGSPVSFGTRITPARTMRGHTRAVTGTGIIGVGRNIVSTSRDTMVKLWDVPSGEVITTLFAKGSIASMSLGDRTPIPPDGEVVTPPKSNDDREVSETKDKMVFCGLENGSFQQFDLGFKKSVYISPSMGVSSISSMAYSTASHLLATGTAAGIVTLYDTRSITTPLTSFSRMQAGVEDLAFLPGGYDEPGEVNVAVATSDGLPFVAGVIPEGPTVNAELVGVDCDPVRHVLYRDCEGKRNVWTASDDGLVRRYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E779</accession>
    <name>A0A9P6E779_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_839380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E779"/>
    <dbReference type="OrthoDB" id="5372118at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="182"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="38786" checksum="D6B86672E887968E" modified="2023-09-13" version="1">MPSVSPQGLQTLVCSKASDVPSFVIDILFQDEVHSNVVLPTLLKCALLERMGTPLLGQLWIICFVWNGNICEIKLIATCTDGMMGKYPVFLYSPVPYSSLHSDPSIRTALDAAGRELFKNVSTRRVYSVFGVDILSRTFVEIWTKNTRIQPMAEPYYSSYISYCTPQTFINKSLTLPYGEYCDLRQATVNDRDGVARLNYIFAKDSEPFILTWEQAYREADELIHKGLVFVHTLGKEPKPAKIVSLVAFTRNTEKTATITKVVTDPEARGRKCAERLTRFVCHQLFTRGRKENIALFVGVNNPAAKVYQRVGFVGIGENPAPANGVEHWVEYGFDRQQVDLGHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E788</accession>
    <name>A0A9P6E788_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4238 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_646048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E788"/>
    <dbReference type="OrthoDB" id="5340163at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025332">
        <property type="entry name" value="DUF4238"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14022">
        <property type="entry name" value="DUF4238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="45618" checksum="1C251AEAD4867449" modified="2023-09-13" version="1">MSNTIVANKKLKAPKKMYQHTIPRFILRQFDVSYEPLPSQVKKDQEIWRQSKRYHAIHFYNLENGCFTIEDLGSVYGETNLYRNQKEPRDVDYLEHRLGNLEQHACSAIKLIHYGILCSSVTFTRAELVSLRKFVFLTHYRSAAASVSYFCESDPRNASLVDWIESLKTSHGLETDDDVWKEGLKYYLDTSHEDIIAAGQALRYRYGEQQLQKMLQSRVDPELEEWYAIDYENQAKNFCLGIWEAATGSEFVLSENGSGIWDRLIYGSPGTHKIYVVQVTYSEDLSLDLHPTPNKLRPSLLPETPDDRFIFKFTKLSFDQTYSVNEVLLRNANVKHRGSITFLSCRLMLQTLKRYLASGNPALLEEKALFRPLVESLSSFQSKMTKEKSSQGTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7X3</accession>
    <name>A0A9P6E7X3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_861891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9523989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7X3"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="253" mass="28604" checksum="CC10208E569441E5" modified="2023-09-13" version="1">MSDNMSYSTNQYLPPPQYYQQPNIGSPVQPPPRPELAQRKRPKYTRSKTGCMTCRVKKIKCDESKPVCMRCTHGSRECSWPEGVPARKKSNARKDSIDERPSTAGSSGMSESPTPPTREDSPPRRNTLDLSLLPLPSRPSDAFASLHSLGTEHDSIRRPLERASSYTQPSSHMLSLMPETQYTSRYDHTTYLNGQNARGMPAPYRPTLPHQSASHWGHTESLDPYYHGHHAALQERPLVGHTSQMDHSHNRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7Z4</accession>
    <name>A0A9P6E7Z4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid:diacylglycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7Z4"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="670" mass="75667" checksum="D8AAE01360170936" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E808</accession>
    <name>A0A9P6E808_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_861855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E808"/>
    <dbReference type="OrthoDB" id="289247at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070062">
        <property type="term" value="C:extracellular exosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040250">
        <property type="entry name" value="Nucleobindin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19237">
        <property type="entry name" value="NUCLEOBINDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19237:SF20">
        <property type="entry name" value="NUCLEOBINDIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040211111" description="EF-hand domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="292" mass="33523" checksum="18E39F6E4A28E0B3" modified="2023-09-13" version="1">MNEIMHKLFRLSFLAFIQCAIAHGGHEHSGPAEGETIQQYAQRHMSSEHHIDTFDTRSFFQLHDLDRNGVWDKEEIEAVYGVHHVYSQKLSKDDEEHQKKAEHIVKTVLEHIDLNKDGLVSPEELEKVGLDGLPNFDGLGAEGHHYDVESEFFLHHEEKYHNTPETQTDESYVHPEDLEHFAHHEHIEHDEAEREAKFQGISMEEVLRQQHEAADAAAAADKVPPSPKPIVRTPPPEAQDPEIKFQHAQSEGAKKGEWGTGEAGYKPPKDAGDKLRKNLPYKYKFRRNWGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E886</accession>
    <name>A0A9P6E886_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_898030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E886"/>
    <dbReference type="OrthoDB" id="5197598at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="47289" checksum="4843A431C7B7DD6A" modified="2023-09-13" version="1">MTLPKLTLFGRSLLLFICEIIANAVCWATAGILFGRNKDTTSILTLALLAWDYGMLWTPIISGGIHIQPQNDAIDNATRGLISQEQLPVTCGLFFSLGHSTIVLAVIAKPFLETIAIAISSGIYDRMQKVGDVGGIIGASISGSFLFVIGLANTIVLWQIIGRRRRDKIFERRHAEGESVPNVERDVDHPESRTLMMRILGPIVTFVNRPWKMYPVGFLFGLGFDTASSVALLSVSALGKRDANGAPIPSSHIIILPLLFTAGMTLIDTSDSILMLYSYSGIHEKTWKIFTSSRIDGRVISDTVTSRSQEKNEVGLSHTIEGLPSIQEPTFASTKAKMNVMSELSIILTLMSILVAFAISLITIMGLIGENCRRCVEAADADERHGGLAGRWWRAWASASDVSEYIGAAIVGVFVLVVLSWYGGRWALKRFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8R0</accession>
    <name>A0A9P6E8R0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_607236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8R0"/>
    <dbReference type="OrthoDB" id="3226552at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="182" mass="20457" checksum="8062175E10B2BA9F" modified="2023-09-13" version="1">MAIAFPPMLSMDDLQNLPELYYDVDEADDHWSDIIPPRSALTFAVVYDPEHDFMAFSDANILGFNSKQSSCYLLVPQDTSPSRAMTPRNVSRASSEYFDASEEPMEEVMKSYTMEHTSISGLTQTSSTLGGLDVYQRGASLAQTHIRQPIYSILEFEAGFNLDLKELGTTSMYQIVLSRKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9N4</accession>
    <name>A0A9P6E9N4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_944457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9N4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23274" checksum="3A43A98CFDE43704" modified="2023-09-13" version="1">MSTPRSLKTADEVSELLGELDVIIRDGVVNGRLDTAIKEIKDDYRRVQPMRENGTAEQEKGYHGQPLFFLGLIRRCADWKKQNDGNWPKFNELEKIHLEKWVKETRGRPVIAPAEETPAEKPKKIAPRPIQKEAPPAKPKSARPPALQGNAIAGPSKVNEVVYVRRTAPEVPSEGENDMDVDGPKSFQELDQGSDIEILDAAPRRRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9T9</accession>
    <name>A0A9P6E9T9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_860411</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9525013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9T9"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="45"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="434" mass="47013" checksum="8A12DCFAC91783E5" modified="2023-09-13" version="1" fragment="single">MQNADSVVLPHTGDDEHANTSESTPLVGHGLKPLSKRELAISRVQFFALCWSIFLIGWNDGTIGPLLPRIQDYYDVGFATVSWIFVLGCIGIVFGAFINLPLTPTLGFGKMLVFGGSFSIVAYGLQSLRPGWHTFVLSFFIGGIGMAMQDAHANAFVALVKHNNELKMGLLHASYGLGALIAPISATLFAQTPHWSSHYWTSFGLSIINVVVLALVFRLKVQDVCLREGGEHVPEPDESQPPHKFTQILKMKATHLLALYLLTYIGVEVTIGAWTVTFMMIVRGGGSYTGYVASSFFGGLMLGRVILIPVSRKFGEVNAAYLYTVLAIAFQLVVWLVPSFTINAIAVCLIGIVLGPMYPIAMNHSGRIFPRSLVTGAIGWIAACGAAGAAALPSLTGNIAARFGIESLQPFLVVAMAFMGFFWYLVPKHPQRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Z6</accession>
    <name>A0A9P6E9Z6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Z6"/>
    <dbReference type="OrthoDB" id="2988301at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="307" mass="33890" checksum="49668763B98FDFC4" modified="2023-09-13" version="1">MTRWALGVITSRNYEIGWRSSVSNIQNRDTVNDSDNVSQMNVPGVRVFIALNLIGATGLFIVMMTALFSVSVKRLSTWYSFCTSWIISCVSYSLLTFARQQSTQAPDFALCFIQTALIYSVPPLTSCTTLSLVVQILLNFSASLADVPSTTGINTFATLLIGPYIIFVIIFIGVCVYGAQNPITVVKAERGTYCHSTDGSWQKVSFGFVIAVSLVIVVIQAYLARRLYQNRKIMEWKSTTIAMTLRGLLFSLIGLITVMAAMAFIITSSHNLNFDIILAMLPVLAFVVFGTQNDLLMVWFRSCLLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAM2</accession>
    <name>A0A9P6EAM2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_908820</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="2"/>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAM2"/>
    <dbReference type="OrthoDB" id="427800at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1030.10:FF:000002">
        <property type="entry name" value="Anthranilate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.10">
        <property type="entry name" value="Transferase, Pyrimidine Nucleoside Phosphorylase, Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycosyl transferase family 3 N-terminal" evidence="11">
        <location>
            <begin position="14"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="10">
        <location>
            <begin position="92"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="368" mass="39034" checksum="A68B04EFFAE14DDD" modified="2023-09-13" version="1">MAESPQYSESSFQPLLSKLVKRPEYFDPDDLKEALNHLFTPNVLQPTQIGAFLTALHIHRIERRPEFLAAAASVLRDRALKANVLDAETDFVVDIVGTGGDGYNLFNVSTTAGIVAAGAGARVIKHGSRASTSSSGSADLLESLDCLFTAPTPGTSTAIARIPFTFILAPHYHPALANLSPFRKALPFRTMFNVLGPLINPARPKGMVLGVAEKELGATFAASIGEGGVERALVVCGFEGLDEISCAGPTHVWELNNGKVKKTILNPTDFGLPKYPLSSVAGGGPGENAETFKQLLRSGNNIPEKLLPVMDWVAMNASALLVVAGIAKDYVEGAKLAKESIVSGKAWRALEVFRVTGQEAASALTQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAY0</accession>
    <name>A0A9P6EAY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAY0"/>
    <dbReference type="OrthoDB" id="6692864at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10577" checksum="BDFBDDBA49E9A772" modified="2023-09-13" version="1">MTDRNQQYYLNRAHFIIDFLMARSDTTVTAMTSLFYLLISNPGCYKRLQTDVDNAFLKGESASGTLGAATDYQKRDLETVITFIANRYGMPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAZ8</accession>
    <name>A0A9P6EAZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_795892</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="MU157880">
        <property type="protein sequence ID" value="KAF9525757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAZ8"/>
    <dbReference type="OrthoDB" id="1723750at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="402" mass="44220" checksum="A5C1BE05953940AC" modified="2023-09-13" version="1">MFKFDFDIQDVEDGIDEAFNITRNKTEENKNESLQALQLPKPESFAELPIADLLDALPSLISYSPLSVPVSSPRKSVTLLRRDLFDARFQLISEGAGDAVEAEDVLNSSTKKTALGFLENPSDLVPGVYEGGLKTWECSLDLVEYLDNVQYQSNYSFAGKKILELGCGTGIPSAFIVHELFSSQSIISDHQDCPQTVIHLQDYNASVIQLVTLPNLLLAWYASSESTDFRNTLEGDIPSTTESGELPITPELKSTFLEALDKLRISIRFFSGSWNSFDPSSIIPSTSNSKQPHYNLLLTSETIYRLDSLPTLVALMQKSCVGSVTPNCELEDSTLKLQINDSSNVAPSRQSMCMIAAKVLYFGVGGGIPDFLKAVKKVGGQVETVLEKKVGVGRQILSVQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBE2</accession>
    <name>A0A9P6EBE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBE2"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="54107" checksum="B04291B04F970171" modified="2023-09-13" version="1">MPLAKIFSGKRPSRPTTEFVIPNELLELILQMLYNEGHFSSIKACSLTCHHLCSSSQRLLFQRINVKADSLSHFKSSISHYFLPLPAGLIVMLRESSHLVKYVKKFKLELRSQVPKMSVLGVEGGSGSIFGGFTSALHELAPMAVFEPPTEEDIPLVRDFFAGLTTIRLAADHGACPWYLSTSGLIRTLGQALSVTTTLKTLDVTGVPDFPIALLKGCTTLRKLKVLRLVEEDHAEVQVTELVNYLSEAGTSVVSADQDTRCMPTFLHLSAQSSIHTLQLLRCPRGAVNFGEIRELSIQWGQYSDLQECGIRVSDWPRLVGLRLRALDWQLFTQYNTSSSIRKVHRQPVPALTTFNALQTITICAAFQIWLVPNYSLIDYFTSPLCWIVDVLESASQSRHTLTEVVLKLDFKNFTELEGMILSKFDWSPLETLYRSFAKLVKVVVYFRISTPEQERRLLSNEGLQRLKLQNFEFQFCIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBS5</accession>
    <name>A0A9P6EBS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBS5"/>
    <dbReference type="OrthoDB" id="3266451at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="57847" checksum="E2B815E517701855" modified="2023-09-13" version="1">MVSRCDVAFSPIQNLPLEIIQEIALWAQPEDPNARLDDVPISMNQVCSSWQQAISIFPVVWTKLSLILTSGFNLEALRYSLTRYLQRAGELPITLRLHLYKPGGLVPDSDSEEALTDEEITRSRLAHQHAHNAAIDLLTWLFSKENLTCHIKRLQLITSLRFNHIFPLSSAPPDLSKLEFLEIGKIDEDHHDDGVDLGNLLDRAPSLYKVIILEASLDKNSLEQRLPLPQLRSLYLSQLLSPIELVNILNECPNMQQLRVVLTGPSVWEISAPVGKHCHLRDLQLYINDESPDPATVLELQIFANLTRLQLDFSDEYHGYNYDQHLPRPHLNLQNLQRLSIQDMYFTPTNYLFFFDQCPRLSDLFIVTDICHITSVAEAFDNPSPDEPRLSLPNLQYLSIGFLNHPYLDPLSGRYQPPSRTEERDVVSLLDAIHSRTNSCPPNTAPSPEKCLSKCSLVLSLDEQAESSEMIRERITLLKKLISLEVNGSITSSSVVLNRTFGVDDWFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECG9</accession>
    <name>A0A9P6ECG9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein CPL1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_770291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECG9"/>
    <dbReference type="OrthoDB" id="439917at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048661">
        <property type="entry name" value="CPL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038955">
        <property type="entry name" value="PriA/CPL1_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35192">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21671">
        <property type="entry name" value="CPL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein CPL1-like" evidence="2">
        <location>
            <begin position="132"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="20831" checksum="ECEDF86AE82F511D" modified="2023-09-13" version="1">MSTGSKDCGKSQFWYDKKSCCLDQGGPSNPPAPPKGNTCNNNSEYWHHEKSCCVPRCPAGWTYDSNKHECKCPTPPSPPSNPPHPSGHPSNNNNNNNNHNGHSYKKRSAKSRSEMCPLDLYACPIADVAGDFECLDTTQDLVSCGGCASEGKGQDCTKIDFVDNVACEAKACKVYTCESGYKPSVDGKLCQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECK0</accession>
    <name>A0A9P6ECK0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_896064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECK0"/>
    <dbReference type="OrthoDB" id="5348546at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="828" mass="90270" checksum="7254D79FB9F27255" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDC0</accession>
    <name>A0A9P6EDC0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_937198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDC0"/>
    <dbReference type="OrthoDB" id="3069822at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054722">
        <property type="entry name" value="PolX-like_BBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22936">
        <property type="entry name" value="Pol_BBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel" evidence="1">
        <location>
            <begin position="168"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="38475" checksum="2471730554B5EC50" modified="2023-09-13" version="1" fragment="single">MHPYKPAHAARRLADWMGVTPTIESLKIFEEIAHIEEVPPSPPALFSRLLLPPPVASSSRLTTEDLHVPAKGDFTMDSNMDGDEDEEMLYSWGETPLEGDLFEDYGRQVPNDSLSDCTLTCPPPECEGSRLSCNIVYKNKFSYLNHFANCGVCKGKKRTNDGDYNVLWIMDSGASLHFSGKSTDFADLKLFSKDQRPKANTANGVAEIQGLGTVFIKHQVTDITARDKMVEIHTRLFPVYYMEGMSSRLLSMGDIINSGSRLKGTNNVLTFWNDHGITMEANTHQHPNIYWVESAIETGVELNNHVSVYSLDYDTLHRRMGHPSDQVLEKFKNHSDKFLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDH4</accession>
    <name>A0A9P6EDH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_856938</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDH4"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="10">
        <location>
            <begin position="54"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="11">
        <location>
            <begin position="204"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9526990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="282" mass="31823" checksum="9B61CF563814EF14" modified="2023-09-13" version="1">MSRPELQAPPEIYYGDTEAKKYTQNTRNQQIQRDMTYRALELLNLPPDQPAFLLDIGCGSGLSGEILDEEGYLWAGVDIAPSMLEVALEREVEGDLFLHDIGQGFGFRPGSFDGAISISVLQWLLNAETSHPTSSPPHRLHRFFTTLHSAMRNPSRVILQFYPSSDDQIQLITSIAQKAGFGGGIVVDYPNSKKAKKVFLCLLVGGGGSQQQVPQGLQGDEEHDSKAVFEKRRERMKSKHGKRKSVKDRDWILKKKELYRKRGKEDVPNDSKYTGRKRKTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDK3</accession>
    <name>A0A9P6EDK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDK3"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17326" checksum="4CEE2C2910DF4AED" modified="2023-09-13" version="1">MNKDGEAERLLLQVIEGSKSALGDEDVDTLDAAEVLASFYISKERWDEAEPLLSQSIESRKKTNRQGPSHPATLRSMEILANLYMGMARWEEAATVLEEIVTKRDALTQLGPDHPHTFRSIDLLSQVYRKLERWGEMDGLRRRMLRARTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDK7</accession>
    <name>A0A9P6EDK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_769380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDK7"/>
    <dbReference type="OrthoDB" id="2108at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="94"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="486" mass="54031" checksum="3F907D33605456B3" modified="2023-09-13" version="1">MLFHLPHVKSFTNVVDQVRDVIKHYKHEKESEAHQIFRQAANSHQPKGGLPQIVNPDEETVPGIEHPGSTGVIYCSDRAMANGFSYTSSHEWANLGQGAPEVGPIPDAPPRPDSIPMPLDSLEYAPTTGVKGLREAVANLYNHTYRQGKASQYTYENVCIVPGGRSGLSRMAAVIGDVYTSYQVPDYTAYDQVLSAFKRLVPVPTALDPKTNYGFDIEQAKKDIRNQGLAVILASNPRNPTGQVSVGGKELQEIVGLSREGTTVILDEFYSWYIYPKNGEFGKSISSAEFIDDVDQDSVVIIDGLTKNWRLPGWRVCWVIGPKNLITALSQSGSFLDGGANHPMQLAAIQLLDPEHVRQEKLALQKHFKAKRDHVLKRLKEIGLPVDVPPNSTFYIWLNLEKVPAPLNNGLTFFEELLKEKTIVIPGIFFDINPAHRRNLFNSPCHHFVRLSFGPPLKDLDMGLDAIARVLKKVTNNKNNHEFGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDQ3</accession>
    <name>A0A9P6EDQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-xylanase</fullName>
            <ecNumber evidence="6">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_856672</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDQ3"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF76">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040434010" description="Beta-xylanase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="8">
        <location>
            <begin position="49"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="341" mass="37377" checksum="A0E25B9B2C018D63" modified="2023-09-13" version="1">MSRLIGLIFATILLSHSYALTTNPLVARTSPTGLTAKFQSKGKKFWGSAADPNTLSKPGVVDILQREFGQVTPEYSMKWDATEPSRGVYNFDQSDQLVNWAVSNGKLIRAHTFVWHSSLPSWVQGINDHDTLTNVIANHVGALAGHFKGKVYCNISNGLSRFQWDVVNEVLNDDGTLRDSVFSRVLGESFIPLAFKVARDVDPGAVRYINDYSLEWDSPKTRAMVDLVNRINANDGSQMIQGIGSQMHLEPGKTGGALSALQILAGANVQEIAITELDIEFASPDDYKTILSACLQVSKCVSITSWGVSDTDSWRASFTPLLFDGNYNPKQAYHDVIGAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFT7</accession>
    <name>A0A9P6EFT7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="8">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_813268</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="8"/>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFT7"/>
    <dbReference type="OrthoDB" id="3156236at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08987">
        <property type="entry name" value="GH62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005193">
        <property type="entry name" value="GH62_arabinosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40631:SF2">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40631">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE AXHA-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03664">
        <property type="entry name" value="Glyco_hydro_62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040428504" description="Alpha-L-arabinofuranosidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="38555" checksum="65D38A8FEE90577E" modified="2023-09-13" version="1">MVKLSITYFIWATALATLTAAASLYNLPASLPTSFNWTSSGILISPKSDSYEIAGVKDPSVIYHEGRYHVFASTAKLAGYSLVYLNFTDFAHASSTNFTYLDTTSIGTGYRAAPQVFYFTPTKTWYLVYQNGNAAYSTNSDINNPNGWSSPKTFYPDMPTIIADNIADGYWVDMWVICDSRNCHLFSSDDNGHLYRSDTTLSNFPSGFSEPVIAMQDPDKYRVYEASNVYKVNNIYLLIVEAIGTDGRRYFRSWTSSTITGTWHPLADSESHPFARANNVDFNDTTWTQDISHGEMVRTIVDQTMTIHPCNMHYLYQGMDPSAGGEYNGLPWRIGLLKQTNSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH88</accession>
    <name>A0A9P6EH88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_893970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9529012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH88"/>
    <dbReference type="OrthoDB" id="3254241at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="18099" checksum="7B959D100CDDFE2D" modified="2023-09-13" version="1">MSEVQTQLQVPVLVWIDDNNEYNQYEIQHADSIGIQVIELNSTAEAKAWVQANLEFIRENDQPSRLRFISDNVRRETNERVGDYLNVDAGQSILRFLREQSINAPVLIYTSASIDSTRYVESFGAAGSTTSAEVCLRYIENLSARKNNDVGWQEFYAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHC4</accession>
    <name>A0A9P6EHC4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_853653</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHC4"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069:SF1">
        <property type="entry name" value="PROTEIN MSS51, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="483" mass="53999" checksum="B07A3039F500F512" modified="2023-09-13" version="1">MDPLEIYGVRIPPMAANIHQACYQCFKLQAPDSALQKCSACKRVSYCSTACQKANWSRHKGICKAFKAIELRFAPEIATLTRLDTKEDGTPLDSDPVKLTQCLNQIAVMMMSGLEDILGRKIDIPERNLVGWEPRCLACGRSDTVLRMEAALKGLATPEASLKPCPNCKLSFYCSEVHWALVNDKHSNAPWSGEDGPSQCDANRGCQQDIRFELIMSGANQGEFMWAPERTAAQWKSLKDIAWTEFRPYLVEADLPIPPEALDQMLHSATEGLSMPMTILWALENLYNNETWTKKETLVIDILGAASKELQFSKIFEEILHRLPDVKKLILNFISPELATLTEPKSFSINMDTCPECTQRRRRRTQAHYPQEYHTFIQEKSGHKPDLAVAFNSGASQENGASWLQTMEILVERGTPTLFTAYNQTEAAEEAEMLRSVGAHLHPQLGPGKNQWGSEILRTEPNTVTGFYAVNGWLAGGFPAGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHL2</accession>
    <name>A0A9P6EHL2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Squalene synthase</fullName>
            <shortName evidence="5">SQS</shortName>
            <shortName evidence="5">SS</shortName>
            <ecNumber evidence="3 5">2.5.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_813182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2 (2E,6E)-farnesyl diphosphate + NADH + H(+) = squalene + 2 diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:32299"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2 (2E,6E)-farnesyl diphosphate + NADPH + H(+) = squalene + 2 diphosphate + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:32295"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.21" evidence="3 5"/>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9529002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHL2"/>
    <dbReference type="OrthoDB" id="431150at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055056">
        <property type="term" value="F:D-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045338">
        <property type="term" value="P:farnesyl diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000023">
        <property type="entry name" value="Squalene synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040335010" description="Squalene synthase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="495" mass="56450" checksum="A6C48FD73BE49BA3" modified="2023-09-13" version="1">MGVTNWLVLLLTHPLEFRTLLQFYIYHEQKRDIKSQQEHPTSGWDRESMRRCWHFLDLTSRSFAAVIKELEGDLARTIALFYLVLRGLDTIEDDMTIPDHIKQPILRSFHVHTVTPGWSFNDCGPNEKDRQLLVEYATVVDEVNLLLPEYKAVIVDICHKMEIGMADYAHKAFATGSIYVDTIAEYDLYCHYVAGLVGEGLSRLFSASGKEAPYIAHQLELSNSMGIFLQKTNIIRDYREDTDEQRFFWPKEIWGKDIYGFKEMKDMYANDADTVQRATFVQSEMVLNAMSHATDALDYLRLLRNQSVFNFCAIPATMAIATLELCFMNKAMFQRNIKIRKADAANLIMRSTNPREVGLIFKDYARKIHAKADPSDPNFLRISVACGKIETWCEVNYPTFVRFAPSGGSEVQFDPLDVRTKVVQQDQAFDAELTKRKYAAEIKKRGGLTNGNGKPYSNPSEVSMNEMLLYVGAGFVCLLALAMAGVYGVVKYTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI11</accession>
    <name>A0A9P6EI11_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_765141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI11"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="162"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="935"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="660"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1108" mass="121185" checksum="0BCE25DBE95297A1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJB6</accession>
    <name>A0A9P6EJB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_920826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJB6"/>
    <dbReference type="OrthoDB" id="3199698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041078">
        <property type="entry name" value="Plavaka"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18759">
        <property type="entry name" value="Plavaka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="868" mass="98926" checksum="2F5E252D40874214" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJU2</accession>
    <name>A0A9P6EJU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_905514</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="15567at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="1448"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="1594"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="572"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="615"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="681"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="763"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="840"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="914"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="965"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1076"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1103"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1207"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1218"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1280"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1369"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1417"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1431"/>
            <end position="1440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1657" mass="181465" checksum="C427AD8EB4AC02CB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJY7</accession>
    <name>A0A9P6EJY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJY7"/>
    <dbReference type="OrthoDB" id="2864141at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="83" mass="10108" checksum="87BFED10B24A4816" modified="2023-09-13" version="1">MAYVVRDPRFSMSHTDPEMPMPIVHFPRRTYARQIERRLISLWKLMTRNGRKQPRNSFISRDFINVTSRRRSTYHPQLQVGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK70</accession>
    <name>A0A9P6EK70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_185667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK70"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18323" checksum="A450EF4CA34FDC92" modified="2023-09-13" version="1">MALTKETLPSMFLRLHFSLSYLRSRSNSTPPDFNRARQSRLSFESKTRQKKSMLLQTSSISGVEVRLSVVHAVRADERSGWRSMRLIIEDSCLAAHVNYAFERDFFAKSGSPLRLYSANSELPIGCSWVIELLLKSRALKDEVCVVVPNAGPKELIAKLVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKD5</accession>
    <name>A0A9P6EKD5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_850983</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the WD repeat peroxin-7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKD5"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005053">
        <property type="term" value="F:peroxisome matrix targeting signal-2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="111"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="154"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9530470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="38553" checksum="689D6D1B3C652AE4" modified="2023-09-13" version="1">MSSLPQPPTTIQTPGFAHYSTSWSPFHTSRLALASAANFGLVGNGRLHLVSVTPGPARLPALNIEKKYETQDGLYDIAWSEIHENQLVTASGDGSIRLWDIMLDEHPIRAWQEHTREVFSVDWSNIQKDRFVSSSWDGTVKIWTPDLARSVLTLQAHHACVYQALFSPHQPELVASCSTDGTVKIFDLRSPSYLTTGPNTNTFTNPISTAVLTVPASGTEILSIDWNKYRPMVLASAGVDKVAKVWDCRMVQTGGVGQVGGSCETQFLGHEYAVRKVQWSPHRSDVLATASYDMTCRVWTAMPQADRPQLLHIHDPHTEFVVGCSWSLYDEGIIASCGWDGRLSVFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELI2</accession>
    <name>A0A9P6ELI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_786609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELI2"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="341" mass="38909" checksum="C694EEEBB4159BE0" modified="2023-09-13" version="1">MTDWNSIQEITKDVNVMYKMAYILLGLYTWEWCTSLQLELDVLAGRKKFKWPMLFYFPCRYCPLLYLAAVDRSLILRLHPVRCGAIYVIVLFSGLGSTAFASFNLSLRTLALWENNRYMKIFVFAVFLGHWSLVGALAPYSFNSTWKKGLGCTQGIPNLRGNIIIHVYTLIVDFVFLGLALYKIMGAGTSRISIPLKRQEQTGRVAYVFFSQGISYFTITSILNLVSVIFYIIDLNMAMAVVVAFPTTLIIPLLACRMVRGLIFFNKADEDIRARTSRHFGAQRNRQTSRIWLGASQSTIFQTFSVSATDLWRLIHSPDPSTLIVDVDFLGMFSLPLLFNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELS5</accession>
    <name>A0A9P6ELS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELS5"/>
    <dbReference type="OrthoDB" id="3056056at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="330" mass="36414" checksum="32DA5F93DA7A8C68" modified="2023-09-13" version="1">MTSPMTKPIPLVLPEIDLVANAKTTRKTFERLASFSHLTCNEDSPLLAKTLAKIHGLVKLVDTSMVAAHLGYRLATSAMILCDSEEQEWEADVSLENLKELVAQGVSMSNEVVVGFRDVQQEIYKIAASTKDSNLLVVVPPDATHADEIKMQLKGVGTGLVANMKLLSDFSRIANETAEWWSAIDNELQTHAPQLLPVPEAPNATDAPSPEDAEKFAEWSKMKDSYQDYYNQVNVIHVSFPELLGPSITAWKAVATAQSLPSSEANSLVDLGEHFQKEEPSLKKGKRKTISRFFSSKPRGKEDVQSKKRKNQEIEHPECSCSCHGIKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM28</accession>
    <name>A0A9P6EM28_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_807336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM28"/>
    <dbReference type="OrthoDB" id="70588at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02957">
        <property type="entry name" value="Phd_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051499">
        <property type="entry name" value="Phosducin-like_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052:SF1">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="3">
        <location>
            <begin position="168"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="378" mass="42734" checksum="03772088F2F6A9DE" modified="2023-09-13" version="1">MYADIEALVLSGELFNGPSRSSSPTRSASPTSDPGWHDEELVASKRQEYNEKGLDYDSDTARRDALSEKRLQEANAANSIGMGPGRTGVKGVIRDRDEANHLERNKKAKEVDEVRKKMEAANLGGKTYLEEEREKAARGTGEKVDLLVRQEQEKVTSVRRGLFGQKEGRFGHLREVGLKGFLPAVEEEKGVWVVVHLYDASLERCYIIDERLSRLAREFPDTKFLRARASVLGFASTSTSTKPKPKQNHKSALARLKTPREEDEDDPYGNDNEEEDAEEEMDADDDVDLDMLPTMLVYRDGDLVHNWVRVDWEAGDAGLDELLDRQVFFFDNYPCLLFTDTDTDTMYSRMLDDERTSALGVMNLTLILRSAMRSEPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMD4</accession>
    <name>A0A9P6EMD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_131007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMD4"/>
    <dbReference type="OrthoDB" id="3067012at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="556" mass="62332" checksum="45F438FC7A186A5A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN07</accession>
    <name>A0A9P6EN07_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_848392</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN07"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="293" mass="34234" checksum="3ABC3931842C6DDC" modified="2023-09-13" version="1">MPYCERCDRSFRNISAMEQHQRDSSEHYICHDCDRDFTSWNALQQHWLQSPLHEYCQDCDEHFDDHDDLEEHLESEHWYCGDCERVCKSEMALKAHYRQSDNHYYCEPCDRHFLNENALRNHLNSSTHQPKNVKCPFRGCGKAFVSRAALVLHLEGGACPSGVDRKTINKLVHKYDKNHIITDPSRLIGGASSNDSDEDVEDIATERSWNGFGYECYFCQKEFPTLKRLNQHLASPVHKAQIYRCPGRHCEAHFSTLSALVQHIESQKCDVYENRAVKKDMETIFKQMGRLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENT3</accession>
    <name>A0A9P6ENT3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL46</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_867703</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENT3"/>
    <dbReference type="OrthoDB" id="414075at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04661">
        <property type="entry name" value="NUDIX_MRP_L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021757">
        <property type="entry name" value="Ribosomal_mL46_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033650">
        <property type="entry name" value="Ribosomal_mL46_NUDIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11788">
        <property type="entry name" value="MRP-L46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL46 N-terminal" evidence="9">
        <location>
            <begin position="27"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="277" mass="31689" checksum="DB55EEC164ED15A7" modified="2023-09-13" version="1">MLATEATEQLPNIPPQATRPKKTVKAQISTAILLNRSPTITRTPGQFERAYFAYEQRLRRALHNPFPYDFYFKQGTLLETRFNLEERKREKLAFGPGFLEKENISEEKRAADIAAVETLAQQEGEGEELMPRSHSADEAADVKSLDRAGTRNLYLLLQTLEDGKDVWRFPQGEVENSQFLHQAALSDLYAECGDQMDAWIVGKAPIGVYQPSQDAKSVTSQNTPERYIFFYKAHIMAGQIHPAKESVKDFAWLTKEEIEPRVDRHYWEGVKDILSDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENU3</accession>
    <name>A0A9P6ENU3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Argininosuccinate lyase</fullName>
            <ecNumber evidence="4">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_847589</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="4"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENU3"/>
    <dbReference type="OrthoDB" id="2561043at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000002">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000001">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000002">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Argininosuccinate lyase C-terminal" evidence="8">
        <location>
            <begin position="370"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="464" mass="52324" checksum="6804E25CBD3614CC" modified="2023-09-13" version="1">MSEAPTKQKLWGGRFTGKTDPLMHAFNQSLSYDRRMHSQDIRGSIAYAKSLTKVGILTKEEENKITQGLESVEKEWVAGSFEVKEDDEDIHTANERRLSELIGPLGGKLHTGRSRNDQVATDMRLWLLDEVQEVEKAIKGLLRVLVERADNEKEYLMPGYTHLQRGQPIRWSHLLLSYALSLRYDAERLHQLIPRISVLPLGSGALAGNPFAVDREFLAKELGFQSVAENSLWGVADRDFIAEFLTWASLTMTHLSKIAEDLIIYSTAEFGFISLSDAYSTGSSMMPQKKNPDSLELIRGKTGRLFGNMAGFMMSLKGLPSTYNKDLQEDKEPLFDTVDNISACLKIAEGVISTLEVHGEKMRRALTMDVLATDLADYLVRKGIPFRETHHVSGRAVALAEARQCQIADLSLQDFKSLNGQFEEDVFKVFDFEASVERRQAIGGPSRRMVERQIFVLREFISKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENV5</accession>
    <name>A0A9P6ENV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_890353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENV5"/>
    <dbReference type="OrthoDB" id="3269067at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="471" mass="52058" checksum="501833D587F0E4AC" modified="2023-09-13" version="1">MSSMNPSAMLAESLAEFSKSAYQAFTEIENKARQEVTRAAQETHDAKAERDTAMKDLHAAQLESQSWKQEAAASKATLTQAELTITHQAESLAAQVEQIAQLRREVTQWKDQSRNWQEHFLRVEQERCAQSSRIDELVVEKLQYVRPPTSTANYITPKHPKYTSQISSAPTTIGKHAISSPTQPPAYRSAGSPSAEPDTSNADSRQTPLQNYTSERGSGSRAHKTPAKPQNAHRRERDAHPDVQEIAPPAGTKPRKGGITLTSSNAQAVSAQLQNVATPSGSNIRSSTVIRRVQAVVHVKREEDTEDEGAGGAIGGTSKSGSAKPNGTVVKRKKKEESLEGGGKKMLNNRKKGIARGRSRSKRVITEDEGEPEEEEEGENDSRRGTERSASQDDDADEEEGSEERGDADKNYNLRKPYRPNYLEEDDEEDDDDELMMGAEDNHDEVYGSHPVDSSRRQNGSPRKKRKFSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQF8</accession>
    <name>A0A9P6EQF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance-associated ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_942912</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="952"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="997"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1092"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="265"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="663"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="957"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1278"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="362"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1529" mass="170833" checksum="1ED4CE10FB275A14" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQM4</accession>
    <name>A0A9P6EQM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60s ribosomal protein l5-b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_831393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQM4"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="6">
        <location>
            <begin position="238"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="34262" checksum="E7A3539663D12B36" modified="2023-09-13" version="1">MPFVKKIKSSPYFSRFQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFTNKDIIVQIVYARLQGDFVLTSAQSRELPRYGINHGLTNWAAAYATGLLAARRALKKVGLDQKYAGVTEPDGTIKITEALEEDDAPRPFKAYLDVGLRRTTTGSRVFGAMKGASDGGLFIPHSEKRFPGFDPESKALDAEVLKKYIYGGHVAEYMESLEEEDDERFKKQFASYLADDIGSDDIEEIYKNGHAAIREDPEFKPTDKSKDYKAEGLKHKVRKLTYEQRKQRIAEKIEKFKAGGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER41</accession>
    <name>A0A9P6ER41_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AN1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_845100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER41"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF20">
        <property type="entry name" value="ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="28487" checksum="8C937EEB2EF22935" modified="2023-09-13" version="1">MASDIPHVGAHCAVASCNILDFLPITCQCNQKFCSDHITPNSHDCDTILKADLAQTTFADKIHRCTVVGCGKLSLNGPNGAANETCPFCRYALCATHRHQDAHKCLEDEPQAHRNVSTKITTLIKPSTKGVRYRKPPTDPAKLAQWQRVELLKMQHAAIPVDPRDQDKAVPLDQRVHAVVAGDEVEKAFWFRKTLVAGKAIDLLCLQLGLNSTDDTRILLIKTSINGDQTTLRNNLPVAEQIENGCTLKMERCAKETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESW1</accession>
    <name>A0A9P6ESW1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_342168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESW1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040204651" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11874" checksum="783E0973A8596A33" modified="2023-09-13" version="1">MWFVNTSHRLMFSRALATSIFMSRAVQSMALLPWRRARVLVLMGMPPPPREYANLLSHRTAQFPSALLHLSPRTLETIHAPGGTPFATMQNLSICSLSIGHFISVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET88</accession>
    <name>A0A9P6ET88_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peroxin-10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_842297</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET88"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="276"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9535766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="328" mass="36917" checksum="51B8540094615E84" modified="2023-09-13" version="1">MSNDPSSSSLSFPRAQQAQIIRANQRDLYHVASLRDQADNVLRSWMGTRWLSRWDKELDLLIKLCYFGLTTGRATQTLGEEYTDTWQYSSRTGHAPPSPAMRAALLALSLGPSYIFGRWGQSASLNESHPTFAKWIKRIPTTLDIVMELNLAVFYLRGTYYDLTKRLLGIQHLSSIPDNPHIRPPSYSLLGVMITVRLLHRLALYFRERSANSQTLKGNGKKRLVSSLEMYLDDRPLSTLLDGVPEGDPARPAEEDEGTALAVTAIPDGIRASRNCTLCLEERTDSCATECGHLFCWNCIVGWGREKPECPLCRQALSLDKLLPIYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETE2</accession>
    <name>A0A9P6ETE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit K</fullName>
            <shortName evidence="4">eIF3k</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">eIF-3 p25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_39008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETE2"/>
    <dbReference type="OrthoDB" id="337745at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03010">
        <property type="entry name" value="eIF3k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="46"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="238" mass="27067" checksum="9651B707EDBE0657" modified="2023-09-13" version="1">MTSEWLSPPTRSEIIENLVSGVDRYNPANVSILEDYLYHQLRTGEYDCLANLAILKLYQFNSELYNPDVIINILIKALTTCPLPDFNLCLSLLDERLINTPLEEPDPLPVILPELKTLHNLLYRCRFPAFWDAYRSDELEQLRDNYTVEIVGFENAIRAVAIRAVRTTFTKISSDRLGSYLSLSDDLVQYVKSLGWSIDPSTTVISLPPNPDNQIEATVVQESIKLPQLTKIIAHARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETN0</accession>
    <name>A0A9P6ETN0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETN0"/>
    <dbReference type="OrthoDB" id="2904962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="471" mass="54135" checksum="B0ED870898E461D3" modified="2023-09-13" version="1">MKRLSKLFSRTNSTEPSKPVASSSGSQFIQKPLPALPSISSSTEIVVKDYQDSDDISDSESEEDLDYYAYFKQSKPQSLFSAKSRAVQWSLPLPQDIIFEMLDSYFYYGIHKPDLRTLFALARTARCLTFYCRSLIYRSINIGYRTKTRRSLPLHYAELICYCPEVAEFVRTIRIEDTGKLFHCSVPLPEDEQCLSYILRHGYPNIRRMELSFPIMWILLPTTLQDAFQTCFRSPTLCEISITRGRIPASLFQSFIFLEDLDIRCLVSYPDDTAASTHDTCAPRILRIIDFTDEGETLENLFHDNTALSFENIEDCRIHTSAKFFHLLGRGFKKMPTSLVALTLHAASWKGATRVSLSQLRHLRALTLRLTSGEWTEELLATLHSPSTLETLSIFPAYDINYRPIDRIFAVAFEATWPRLQSVCLQFTTQPGVAEEELIRRELPSLDKANVLRIVVVDPDFLVYLRRPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETW6</accession>
    <name>A0A9P6ETW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl CoA binding protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_843234</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETW6"/>
    <dbReference type="OrthoDB" id="346910at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000010">
        <property type="entry name" value="Acyl-CoA-binding domain-containing protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF133">
        <property type="entry name" value="COA BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="465" mass="51303" checksum="3134A1A1CFEB2A71" modified="2023-09-13" version="1">MASYDPVGVQFDRAVEIVQSLPKTGPIQTDYEEKLTMYSLFKQATSGNVKGPRPGIWDMLGRAKWDAWAKHKDIESNEAKQLYVEALLKVLRKYSDKTVARRLVEELESFGDHFDPVLSRSSNRSPGSDASGSTLSDISASATRQVLPGQYPRAQPNGFHPAEDEESAEEDLSDEEARGLPPMNSTRMPLDNRPPSSLSSQQRYRTPLANSLAMSPTPSRSIPSQQPLPSFETPSAFDGTPRALPNPHQLANQSPVSFTQPQTVYPYPGNSRNQMRPYTSTYEAAPSTALERAVEGVQVHLAALTERLEVLESRSFGHSRSHNNSGSLSGPVSSSWLVGGSSQNTRGGGPQWDIDDLGMWSLVLHPLSYGLVRLKEFATFFARNEERSPSMIIVRRLCLDVSFLMTVVMLVGALWRKSGVRRREVKAALVILWRAILGTKPPRQLVHLDLHSALASICASPLLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU82</accession>
    <name>A0A9P6EU82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU82"/>
    <dbReference type="OrthoDB" id="3349961at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="166" mass="19323" checksum="253F3E2192366EC3" modified="2023-09-13" version="1">MMLFHRRETPWEVVDSRCVAPTPIYYQNEELELEAVKQADVKRKYVLDVRPHSKLNAELKKAVVFARDQLLSEVRKNGYNLLLLESWHLTLLRRGKLHRIEVEYTGRPARTPNQISPRPPPFMAVLQHVATLDPEPSVHVTKKQSDKLLLVRLSRRISVCSILLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUM8</accession>
    <name>A0A9P6EUM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF866-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_841630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUM8"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17953" checksum="B327869DBE7E6BD5" modified="2023-09-13" version="1">MVKLKLSIAAELENVTNLEPVGNNFEFRFKVKCSSCNEEHPKTVSLNRAEEYEVSGSKNAKANFVWRCGLCRRESSAKFESTPITPYKAENAQFGPLLVIECRGLEFIGFDPEGTWKCVGTESGTVFSEVELAEGEWSDYDEKASLPVNISKIDSKWERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUT8</accession>
    <name>A0A9P6EUT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_872246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUT8"/>
    <dbReference type="OrthoDB" id="2880862at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="331" mass="38510" checksum="CD7E8EBF2A54D75A" modified="2023-09-13" version="1">MRPILLFATFTMEKTTLKIHCNLNSCTSSDNSDLRCSNCKVVRYCRQEHQTADWPNHKAICNKIKRSRRKTEEEETASPDGFMSSMNPFEISVGYFWGIHETRPYMRARMDLVTQLLQVNTLVSVASCLEHLRDMLRLCRGDNLGVRDIIPGLYLRLNRDQECYDFLKCLSFLNLKNEDVIKGIEVFKSRFECAHAIAVVLLKLRMLLDPRDVLASSVYNTEKLNYDTVRVVQDSLATRSPIWSARPELLAQEGLAERIKLLETQLDALFKYIDRSNKWFWKALLEYEKYLAVPVSAYSSGSREEMVLLIHHSRSWIETEGAIKWVREKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIA3</accession>
    <name>A0A9P6JIA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_911627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157978">
        <property type="protein sequence ID" value="KAF9521869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIA3"/>
    <dbReference type="OrthoDB" id="3439489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23428">
        <property type="entry name" value="beta-trefoil_Ricin_SPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031755">
        <property type="entry name" value="Inhibitor_I66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16850">
        <property type="entry name" value="Inhibitor_I66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="16580" checksum="523732B43B405488" modified="2023-09-13" version="1">MAPSTPPTGRYMIRSVMTRNYIGRSQREDRSLLPKRIVLLSDGVRPTEFVFNTSGREAKITAGGSPTAAIDNKLYSVLLDTPPAQQWVVQRVSESGPAQYIITTQDGSAAWVVSGQDPESQVSVLQSVRFDPSTAAPYPPRALWDIVPLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JII7</accession>
    <name>A0A9P6JII7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157960">
        <property type="protein sequence ID" value="KAF9522110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JII7"/>
    <dbReference type="OrthoDB" id="3262423at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47132" checksum="FADA35B7E2A86B31" modified="2023-09-13" version="1">MSPSYCFLRLSFPMPTSNPQSAPMAGQSPVHSDWQRQDSGLTAFFRRNRFSTVSTLTNASSETTLPEYSEVDNASTVDNTTLGSLDQPVSPSPALDTLAEDHSMDDTESSYAYPIGQEKPWAVLHLKSCLPSTPSLPILVGNTALKGSLALKSQSAESIQEIYITLKGKIQISSSDVGTETFFHQRFTIWTKTTGSSPLYSPEEGDDFAWAFEEKLESQRNFPFSIPVPTHVDFATKQAVFQSTIDPSSSVMPSLPSSFSETGIPVEVHYSAMATIVLGRFRKDGRIKAGVIYIRGEQPPPLSSLSRRTAYNTPISTLLPRVLPGPDIDPTGWDNHPKVTTHGFFQEEGGTSRWIEHSFLLSLALPRTYARGTVIPCYIQMSCADEVAVRYLGNPKAPCVRLVRRVTYTLPINDHLRTSSTIYESYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIW2</accession>
    <name>A0A9P6JIW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIW2"/>
    <dbReference type="OrthoDB" id="2893947at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="19846" checksum="C8409DBBA382A13D" modified="2023-09-13" version="1">MSSLPDYVLAILLASTFVSSIIVIFGSMCLSVSLILWAIPASIFLTLVHHLTTFLIRGLQKSNMPRIYTLASIIFTFVIAILWLACLAISATIMALLFCGRVHAKDDQPKVVLGLLSGLCLLEVILMAFLAIRGVRERKQIQYTEKWTWRTPQGGFSQANGESLLTFASKPILPMFRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJZ5</accession>
    <name>A0A9P6JJZ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_656828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJZ5"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045340">
        <property type="entry name" value="DUF6533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20151">
        <property type="entry name" value="DUF6533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6533" evidence="2">
        <location>
            <begin position="14"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="33113" checksum="2D028EA87C5E7482" modified="2023-09-13" version="1">MSSREQSALEFNFVISSLTIIIYDILLHIPEDLRLFRKHPIRLPSLVYAGARASTLAVFIFAVAIIPLVNPFLFSIAHVYSPAQGSVTIWTLYALLMIQRGTTSLLLYLRVYALYQSNRYVQTFFLAALLGVTATPLILFGMSGIACSIFDLGILVAILWKVKWHRPTIYYSSPSSEPEANGRWTYWNPFKCGREHEVTDQFLKGTLAYVLLAILIKIPQIFALTGAIGIWPIYTTYPELVVSCIVSCNIFRNLKLGLSRHNGSTSTSILTTPRSRLEFRIPESRNDESDSLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKM7</accession>
    <name>A0A9P6JKM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyruvate/Phosphoenolpyruvate kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_861424</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKM7"/>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="38"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="274" mass="28725" checksum="70BF40B29CA74B76" modified="2023-09-13" version="1">MATHALLNAFKSKTPAFGAWLTLPGAFHARTMAQASPHLSWIVIDCEHGLVPLIPGVAEAVSAIESAGNSTNAPPVSAIVRIPATGVTASSSWQIKHALDGGARGILVPLVSTADKAKEIISDARFPPVGRRGFGSPFTHGTWGVSAKEYLATSNESILVVVQIENREAVENVDSIAAVEGLDALFIGPYDLSISLGYPTPDPDPHPEVEKVIQKVLKATHNAGKKCAIFCSTGEQAAIRAKEGFDMINVTTDTGAMTEGISRHLAAALSTSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKW6</accession>
    <name>A0A9P6JKW6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_909810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKW6"/>
    <dbReference type="OrthoDB" id="10260758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="464" mass="55390" checksum="99CD2A337F7DA2AF" modified="2023-09-13" version="1">MNKFLNMYLRRLERKKPEARFAKIYYSTFQTLGQRANTLEELDSVSVAKDNDSKDDVEIAARMMRLADRYWERYCEHYGSEGTNQGQELQWQAYNILCQKLGPWHYHTKRALWHVCRWDISVVEQREILDKVVAHMEEHNQAYYQFNSSLMEAVVLCCLRNEDYSDNAKTLQLMLSRTRGLGSSTLKKFYDVYRMLFAIYLGRQEWDEAEDLIKEIRKSWQANPQQGECHAMTAEIRLRQGKLVEAEEELLTGVTLEADGHMLDGYFSCRERLMEFYLQQEKWILAEDLGRHLVQVREDQISEKVRPRSKSSQDLEINWAKATQKAARVINMNRWRIFEWLENQEVYYLHALYNNKRQLAFVNKQLKRYNKAQVLLEELMDGKMHRENPILVASKELLVTLFIESGQFDEAEKKQEQIVEEMSETFGYDSKKLITELERLAYIYQMSKHLGKRHHVKLRLLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL41</accession>
    <name>A0A9P6JL41_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_909574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3071207at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="584"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="898"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="977"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1068"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1281"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="818"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="229"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="689"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="700"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="901"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="939"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="985"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1079"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1114"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1291"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1318"/>
            <end position="1338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1378" mass="146779" checksum="5BBFB510C82BC989" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLF8</accession>
    <name>A0A9P6JLF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_599554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLF8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="526" mass="60303" checksum="1514193A75C37026" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLV9</accession>
    <name>A0A9P6JLV9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Bifunctional purine biosynthesis protein ade10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_562481</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLV9"/>
    <dbReference type="OrthoDB" id="6017153at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.20:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="600" mass="64750" checksum="4ECEC94E5A6B270F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM76</accession>
    <name>A0A9P6JM76_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_870910</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="9">
        <location>
            <begin position="2033"/>
            <end position="2379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="453"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="649"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1332"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1594"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1835"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="482"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="505"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="600"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="656"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="676"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1347"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1607"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1633"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1660"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1841"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1851"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="2346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2379" mass="256968" checksum="D8CCAAEBF1296D59" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMA2</accession>
    <name>A0A9P6JMA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMA2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="74" mass="7829" checksum="151335C534E4C488" modified="2023-09-13" version="1">MQCIDKCANTRYAPDTQGILTSPSQETLTPSSTIASNKSGTDNTVKLASDSSFSKTASRQGWSSNTPTRPTLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN30</accession>
    <name>A0A9P6JN30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_817278</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN30"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="91"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="91"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="31725" checksum="715572F3C44D7D9C" modified="2023-09-13" version="1">MSDQLSNFELHRQQLAAGLVAVAESMRNCAELAETFAKIVADTEHSHEAATLLAGASDSLKGKRKVALSPEVGESGKKRKRNVKPKDPNAPKRPASSYILFQNEVRKELKEQHPNLSNSDLLSLISEQWKNMSDEQKETYNQAMKTAKAQYSEEKKAYDNRTPAEIEAANAATEVAKVLKKANAKRGPKPKDTPAISATAAAVTPAAVPARPPPKLDEVSPDSSESSDEEESEEDSRPVVVNSHHLHHESQSSDEEDEEEEIHEPARKKPRSGSTQPAMLQKAKRTSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNM1</accession>
    <name>A0A9P6JNM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_447713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNM1"/>
    <dbReference type="OrthoDB" id="3052633at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="277" mass="30738" checksum="FDBFF5A8A7349E36" modified="2023-09-13" version="1">MILRTLGFSLFSSLRVYALMEGRWPLALFVFSMFLPSIIAPSFSYANQSSIGVDRFGCQFMSTSSQIVHDRLRIAGIIADLLSETIVIIVTLKRTFHLRGNIPKDEHDNKPGLAALLLRDGTVYFVALLVLSLADMLVLVFDHVPQPVVGYDYWVVPFYTPVFRTIIISRFILMLRAIHYNIDDGNEHYSTGLQFGSRVVGSLGAPVEPLRFVDGASADFDEEEDENIIFSNDPFAAGMLSTSSPPTSSATGSGSETKHSDEMEMYRVHDLVGEKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQB4</accession>
    <name>A0A9P6JQB4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_906705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQB4"/>
    <dbReference type="OrthoDB" id="2742220at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="30410" checksum="A1BF6161797C9173" modified="2023-09-13" version="1">MVDWKSSKELTRDAQIFDKFLHILFGLIVWEYLISLDFEWEFISGKRKFRWPMIFYFLGRYAQILAMIGSAASFDSPTELQCQPLFRFVFFWGFGAIVFSSVNLAIRTIALWENNLYVISAVALASSGQFALVILIVIAIRGTWNPTIGCMLSGGESYTTALFIYTMCFNGAVLVLTTVKLMKMNVNAHSNQMLGQSKLTHIIFADGLIFFIIALLADVIVVVFIALNLNPTMKIVFQVPSSIVSTIVACRAVRRLMNFSYGAPAITFVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQM4</accession>
    <name>A0A9P6JQM4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cdc23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_852543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQM4"/>
    <dbReference type="OrthoDB" id="10262026at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007192">
        <property type="entry name" value="APC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF10">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04049">
        <property type="entry name" value="ANAPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cdc23" evidence="8">
        <location>
            <begin position="13"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="374"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="408"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="442"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="617" mass="70467" checksum="FBD4E3009C702994" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR32</accession>
    <name>A0A9P6JR32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_893094</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR32"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="182"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="541"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="618" mass="68812" checksum="857F180C261265E4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRH2</accession>
    <name>A0A9P6JRH2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_764740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRH2"/>
    <dbReference type="OrthoDB" id="2976497at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="1">
        <location>
            <begin position="83"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="260" mass="29114" checksum="90649D28A502311E" modified="2023-09-13" version="1">MATFAKEFLALQDSILLKAYHRDLGATCACGKFAGLYRCAGIEHCFDNSLYCCNCIVQVHSSGSHPFHRIEKWTGSHFEATSLNDLGYLLHLGHHGQPCPNVSSKRSPRSMTIGHTNGYHTLCVHFCACHLTLSEPLQLCNHELFPASMNQPQSAFTFSLLDLYHYITLASKGSLYDFNASLVEMTNPAFPQDHRYYELGRVTRVWTHLASVRRRGQAHGIDDFIPSRRKGSLAIRCPSCPEIHFNVDLAEILSAGPFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRI0</accession>
    <name>A0A9P6JRI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Tyrosyl-DNA phosphodiesterase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_851827</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRI0"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09123">
        <property type="entry name" value="PLDc_Tdp1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="82"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="618" mass="69754" checksum="92323F446EBF60FF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRX4</accession>
    <name>A0A9P6JRX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_763235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRX4"/>
    <dbReference type="OrthoDB" id="21151at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="821"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="870" mass="95655" checksum="73EDB67A75B6E496" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRX7</accession>
    <name>A0A9P6JRX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_848855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRX7"/>
    <dbReference type="OrthoDB" id="2978551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="679" mass="77445" checksum="6B8E369BBA35CFBD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSB2</accession>
    <name>A0A9P6JSB2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_810461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSB2"/>
    <dbReference type="OrthoDB" id="5399006at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431:SF7">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="26703" checksum="034485A8691F7E88" modified="2023-09-13" version="1">MSSQTAKRVAVVLGLGKGTGTGASTARLFAKSGYEVALISRGGDHLENLGKDIKSNGGNAKTFPLASYSHEDVINAWAAVHKAFPKPEYVVRVAVFNGGWGAFKKFLDVTPEDVQTALQASVAAAFSFARGAILAFKDNDIDESNGKRGALIFTGATASTRGNVITSCFAAGKHGLRALSQSLGKEFGKENIHVAHSIIDGAVLFDTTWKTTDRVGLTPDSIAASYLYLVNQDKSAWTWELDLRPAHEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSV1</accession>
    <name>A0A9P6JSV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_848567</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSV1"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000013">
        <property type="entry name" value="pre-mRNA-processing protein 40A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="9">
        <location>
            <begin position="382"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="597"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="620"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="681"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="804" mass="94169" checksum="C4A6E07583232C9C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSY5</accession>
    <name>A0A9P6JSY5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSY5"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="55" mass="6762" checksum="9A58B60418BFD3B2" modified="2023-09-13" version="1">MNYDKNLDDFGLWKWCGKEGLVVLYFAWRLMFFRSSFIEYKSALMFLEFSIYDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTW1</accession>
    <name>A0A9P6JTW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTW1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6545" checksum="0627DC5770B4F18C" modified="2023-09-13" version="1">MVVTISVLLQALQHFIIMLISFKSFYLIRNSFSSHSFSVSVILPSQFTSRTCAFTLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUI7</accession>
    <name>A0A9P6JUI7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_759305</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUI7"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040421098" evidence="15">
        <location>
            <begin position="23"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9532505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="549" mass="61164" checksum="61AEE8340C402BF0" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUS1</accession>
    <name>A0A9P6JUS1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_846334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUS1"/>
    <dbReference type="OrthoDB" id="10055769at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="228"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1081" mass="121933" checksum="AF1EBF99249E586F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUT9</accession>
    <name>A0A9P6JUT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_542495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUT9"/>
    <dbReference type="OrthoDB" id="3130513at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="256" mass="28132" checksum="B8703BD985770A0A" modified="2023-09-13" version="1">MSGNTAPTLETKVFRLEHSGKALDAKNSLLSFSAPANNPTQLWSSCTGVNGQWIVNRATGAYLVVDSNTVSVKIELPYEWNIQDGGSSVRLKAASQKIYLQSSQQKPAVSPQEDADSLFTITYVTQPVLSVGSEDYVKSPEHTCVTNHVFNAVNALNAVIHILEHPDSTQPVESMVVLFRDHIKLFKARGDEATQNLELARQTVASWFTVIGAKMDAEAKNKGTIESLIRNEDPGLKAAENNWRNSVLRTPRPRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV03</accession>
    <name>A0A9P6JV03_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_843102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV03"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="67"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="213" mass="23400" checksum="8FB744ABC4A584AB" modified="2023-09-13" version="1">MSTNDEENSDRLEYADVIAQVDQIFARLQQEIPPGRLSFKQIEDLIEGLPNVTEQQLIASADKDSTCPICFTSYLAIIAEGELASVMDSPANPAEHHGVTKLSKSWQCGHIFCRRDISKWIRDGHDSCPLCRRLLVERAEGEPQPQPQDQSGISPGTPPHVFIGEESGLDDVLRQLASAGGGFGFFHPPPSSSSGGSRSHDDDDRREYSGMYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVC9</accession>
    <name>A0A9P6JVC9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_879715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVC9"/>
    <dbReference type="OrthoDB" id="5121585at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="690" mass="75507" checksum="A5915DD4EB5635DA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVD3</accession>
    <name>A0A9P6JVD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVD3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22467" checksum="95100D2F665C3060" modified="2023-09-13" version="1">MSSNFTPSNAVDMSKERDWPANLGMLDWDDTSIVFTKRSLIEFLKYTGTTVDTNFYNISKLPKYAKFGKLSEATQEQVKDALEVAGSANAANGFRPSRRVRDVPGGSHTDIFAADEDDALSAAPPKPEEAKPAQQAPVSRDTADDEHQGIDFGSSFKPSRRVRENPGGNSSLSNFWDADEQESFKPTRRVRERPGGKDSISGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVI3</accession>
    <name>A0A9P6JVI3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Galactokinase</fullName>
            <ecNumber evidence="3">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_844814</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>alpha-D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13554"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="3"/>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVI3"/>
    <dbReference type="OrthoDB" id="187738at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF7">
        <property type="entry name" value="GALACTOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457">
        <property type="entry name" value="MEVALONATE KINASE/GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Galactokinase N-terminal" evidence="13">
        <location>
            <begin position="35"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="11">
        <location>
            <begin position="165"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="12">
        <location>
            <begin position="436"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9533944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="538" mass="58443" checksum="93087301EB1BE441" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVK3</accession>
    <name>A0A9P6JVK3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_422685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVK3"/>
    <dbReference type="OrthoDB" id="5231159at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058518">
        <property type="entry name" value="DUF8205"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26632">
        <property type="entry name" value="DUF8205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="35"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="30125" checksum="99AF4A2D59A6EB49" modified="2023-09-13" version="1">MFRTAVHPDRNKQFREQAAPKALIKEGRKEAILACTNCGTPGDEDGVELKRCPKCQISYYCSRECQKEHWPIHKTQCDPSLDGGIQPLIKSVTGNPMLAHYLKICIAFEFNLHIPKNKWEPKSWKAIIRSPLYVHIDVGIEPTKITDFMHLYTFKDKWPGVKKDIDGMLQFHHIYSAKSGLNPEAIMNHTNAQIWGHSREAADEDGLEDNMVVLVRFANDMKQSVTCTMVIDDDALESAREAAPFTQTSALTGKTTEHAMGIPSCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVS4</accession>
    <name>A0A9P6JVS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_831324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVS4"/>
    <dbReference type="OrthoDB" id="5576441at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="507" mass="56347" checksum="520D4681E40ED6E4" modified="2023-09-13" version="1">MPISTYSSRFTDEVVDDSEPEREQLRAQSKSAQQRLKKLGHQTGQLTQVGETVTTLIEISDSESSSEESTPSLPPSSFPETSEPGGTNPTFSLGHFAYPAVPPMKRSTTLQTTDNQSSAPKKPTPYQRPPVRKNSPSNLQLADVNKVSRCVCCHVSWTSRKTAVQKLNHIQSCSKKHCYDDDTIRILVDKAVASSSPPKPKANGKNATPVSTTYLEDLVRDKAPKKRTKSKASDTLITAVENNRSIILARANDIFTSMTPDESLRADQYLAPSTQSFATSSLGGLQGFESKRLLFDDDEASSPTQAFLGNRLGLRTPRSLFDLGDDEDDELTPSSSTSRPNKSRSCSPLAFGPVHRHATVASYSRDVAEPPPDSESELDEPLFQVDTTQRGRPCKSYISSDSNSIVDMPKKGRGRSLSKKTPKSKRVVFGDEWEFYMKQYIIEDDELHLRILRAEPLDFNSFWEIAKRYSPNASTSKLKTELRNFLDNQAILFYESTAWRAKSKAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWM8</accession>
    <name>A0A9P6JWM8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6699 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_731838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWM8"/>
    <dbReference type="OrthoDB" id="3241567at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046522">
        <property type="entry name" value="DUF6699"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20415">
        <property type="entry name" value="DUF6699"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6699" evidence="1">
        <location>
            <begin position="35"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="197" mass="22820" checksum="F9B74768FF6921D4" modified="2023-09-13" version="1" fragment="single">WTPPSPPQWTPSQPTLSIHRHLCYNIMNPNAPPELLWDVIHPPNYARVSDPRHPRMWKKPEFDSEAVQPSVKKVWIVCDHAVLGFWIKKWGHITVTSEKNVTIRDILDGIFKYLRKPLTESDIEDLNTVPGNLDSLDYARTKRAKESLEVDSVVLSSSYRRVDVVGTHRRFAGMRIVVYPDDTWRLHFNLLPGPVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E306</accession>
    <name>A0A9P6E306_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158023">
        <property type="protein sequence ID" value="KAF9521573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E306"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040349270" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="76" mass="7855" checksum="177A1DB0871B15DF" modified="2023-09-13" version="1">MKFAIGIVVTALVVLVQVSAEPIAISKGYEPTEPVINPCEGPNPLVCPDGYHCCPSFIVPGGICFKGSGNPGVCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E360</accession>
    <name>A0A9P6E360_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_194863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158005">
        <property type="protein sequence ID" value="KAF9521664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E360"/>
    <dbReference type="OrthoDB" id="3259878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="30240" checksum="ABA7C02EF763A849" modified="2023-09-13" version="1">MLNNLTEPRLHRLPIRTDYVLIPAPLDLSLPEIAQKSPLPPIIVTPCDPSSTQDFSLAFLPNPPKPSLRERIQRSFSSPSPSPSTWGTGAGASPLSFGAQDEPKLFPINFSSHSHSRSLSETTSSPNRTNRGTLRTRSILAILLVSFLALCHIITHRLAVRMNRPYIDVAFAVQGAGAGGVAGVHDTYVLGVAHAHSNGGVLGSSAPVNVQGHDIHPGYGLGKGGMPGPMISNWFRFRSSSSVTSSEAASAVEGDLEVEVKQAEKGVESVVPDVGAGATTASEETSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3X5</accession>
    <name>A0A9P6E3X5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_748542</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3X5"/>
    <dbReference type="OrthoDB" id="2790258at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="228" mass="26144" checksum="4EDBFEED66EFE925" modified="2023-09-13" version="1" fragment="single">QWTMDNAGNNITAMEKLERSCTQDGIQFDHFGNRNRWVTVQSRYLPLWPLMYTCSRCFPHIINISAQTFRDDHQTIITVTDGNKDGGFQEPLRNVQLLQDVETRWSALNNMIARVIELYPVLTLLTSSSHPSDKWQVLHNILTVLEKAHSAQQLFSAEKTPTLSAALPAFELLLVAWTNLQKEIPELSHYTGASVMKIRERSLQLSIYLLSDVLSVINPAYKMDWINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3X6</accession>
    <name>A0A9P6E3X6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157967">
        <property type="protein sequence ID" value="KAF9521998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3X6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040333627" evidence="1">
        <location>
            <begin position="26"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="73" mass="7753" checksum="A92D833785440D0A" modified="2023-09-13" version="1">MTAKLNIAFLLNAMILSLTVLNVQASPQPLHFKREPACPIICDCPSGYIPIQSPSNCGCNCKPIGSSTPQPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3X9</accession>
    <name>A0A9P6E3X9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_801020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3X9"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="30"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="42729" checksum="51DD9A5714D1D2E9" modified="2023-09-13" version="1">MSFFTPPPEPPTKLGRYRLLSPLAGVHVSPLALGAMSIGDQWDKIGMGSMSKEDSFKLLDAYYDKGGNFIDTANNYQDETSEKFIGEWAEKRGIRDQLFIATKYTTGYKRASPIPQKIMYTGNNAKSLHISIAESLQKLRTSYIDLLYVHWWDWDTGIEEVMRSLHALVQSGKVIYLGVSDTPAWVVAKANQYARDHALSPFVIYQGWWNVMERSFERDIIPMARSEGLALAPWNVVGGGKFRTDEEEERRRQTGENGRTAFGLAWERNDREKAVSKALEKVAGEVGVKHITAVAIAYVLQKAPFVFPIVGGRKVEHLEANIEALSISLSEEQIKYLESVTEFDLGFPLTMIGDGANPSPWISLSAHLDPKPQARPFRPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4B8</accession>
    <name>A0A9P6E4B8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_777359</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4B8"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="64"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="137"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="26764" checksum="6826BE560F79B23A" modified="2023-09-13" version="1">MPRFDELPLAVQEAMTTPFHLILGEGTSEPVPESKSESLNTDAILPNPTPTPTPHTIPTPTPPQKTQKLGSLYLGSLSAVVDPSIAHLRALHISHIVQVMDLPWLVLTKEDGFECYKFAIEDVRTQPLDPEMLQGVCGYIHGVRSASEGQSGNVLVHCQQGVSRSATVVIAYLMRYEGMSLAEALAFVKDKRACVKPNVGFMRCLKVWEEVQIAARARGGAVEARGGGGEEGEDNLVKTEHLKLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4F1</accession>
    <name>A0A9P6E4F1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_118206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4F1"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="27695" checksum="83D837456C6B1968" modified="2023-09-13" version="1">MGLLDHYHQSALEGYFADDCLTDLLTFVTYPDSLWDWIHVWPLLGLMHSETVEREESDRKKLHLLGLKQTYDSYRHILAQYLADETRAGRYHLVEAHYTRVALKVAKYLFEPKQPGKLYLYNLPQEWTWYREGHEDKIFREKKTKETFQAGIQYLPYLLQQSGPNEDLVSYLEQSKLDPIRAQELPRVAWAEDKTKLEAEVAAYLKKYATRANSTRGESNGTNLITPTNGRHKDSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4T8</accession>
    <name>A0A9P6E4T8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_899630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157945">
        <property type="protein sequence ID" value="KAF9522448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4T8"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="86"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="86"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="255"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="474" mass="52664" checksum="87B47196341D348B" modified="2023-09-13" version="1">MPADRTKSLKRSESAGSEFVWAPQQEYFAGPELSFAATMTPIDYSSDTPPPLVDAPPTEFVLFPPAEETAAPRRQPHSKKKPENHIPRPPNAFILFRSSFIKSQHVSTEVETNHSTLSKIIGITWQSLPDQERAIWHQKAKEALEEHKRRFPKYAFRPVQTKAKGAASEKRKVREVEPKDIKRCAKIAQLLVEGKKGQDLENAIQQFDKTHVPEVVTRFEAPITARSYRRSSSAPVVDTENARSEKSFFQTVMDTPKRTYRASSTRPTRCSTPASVQDDSSSYSSPSSSPSPVVEAQTLSLKEEASFNFADFSFDGVTANANTYPCDPLSSIQRSHSFQESPLNNSLTIDTSFMGLDQWAPSPASMSPATPEYMMSPSQDSVVCSSPVSPFASPFDAFDQVPLEKQHFLDDFSDSFPAIYDPSFVAPSQPLGGCEAINDSAMYAAMLQQQQISNFSHGELDFTPFMTSIPQYAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6I5</accession>
    <name>A0A9P6E6I5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6I5"/>
    <dbReference type="OrthoDB" id="2926569at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="93" mass="10936" checksum="F89B3103FEEBBAF9" modified="2023-09-13" version="1">MILSKKLEDELAEFCADGGEIVEWKEGRHRVIEKRARPGDDVEVIVIDEEKYDESNCGHFYSRKWRGKWHDFEKNAEGIIHSLRKELGFSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7B7</accession>
    <name>A0A9P6E7B7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SUZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_774915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157910">
        <property type="protein sequence ID" value="KAF9523810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7B7"/>
    <dbReference type="OrthoDB" id="5373615at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039228">
        <property type="entry name" value="SZRD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31796">
        <property type="entry name" value="SUZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31796:SF2">
        <property type="entry name" value="SUZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUZ" evidence="2">
        <location>
            <begin position="57"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="192" mass="20685" checksum="5D55278D1154132D" modified="2023-09-13" version="1">MASSSGSASKNFTKATKSAAVCDDWEAEEDEEEADPRSVELQNKRIWEEANSRESRPMPAVVMSRGTSTSASLPTLPLNQPPAVRILKRPSGSPSQSSTNANTSAGDTLQDREARYQAARHRIFGTSVPYASPASSSNSLPMQRVIREPRGPEALGDQPNTVNKGFRERKGPSKISSLRSPETQALSDVGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7H8</accession>
    <name>A0A9P6E7H8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Telomere-associated protein Rif1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3259617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1219"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1332" mass="150271" checksum="434AF8310F96F2A9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7K5</accession>
    <name>A0A9P6E7K5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GPI transamidase component GPI16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7K5"/>
    <dbReference type="OrthoDB" id="331263at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007245">
        <property type="entry name" value="PIG-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959:SF11">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04113">
        <property type="entry name" value="Gpi16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040194425" evidence="2">
        <location>
            <begin position="23"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="527" mass="59679" checksum="63DA0D32FE7AE48F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7M9</accession>
    <name>A0A9P6E7M9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_877790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>melleolide F + FADH2 + chloride + O2 = 6'-chloromelleolide F + FAD + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67160"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:167712"/>
            <dbReference type="ChEBI" id="CHEBI:167713"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:67161"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin-dependent halogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7M9"/>
    <dbReference type="OrthoDB" id="3340390at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140907">
        <property type="term" value="F:flavin-dependent halogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050816">
        <property type="entry name" value="Flavin-dep_Halogenase_NPB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43747">
        <property type="entry name" value="FAD-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="580" mass="64008" checksum="20389EC6960CEA41" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7R9</accession>
    <name>A0A9P6E7R9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_898283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7R9"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="104"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="689" mass="78516" checksum="B00EF582D63481D8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8J2</accession>
    <name>A0A9P6E8J2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Signal recognition particle subunit SRP68</fullName>
            <shortName evidence="10">SRP68</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_860894</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the SRP68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8J2"/>
    <dbReference type="OrthoDB" id="10255118at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15481">
        <property type="entry name" value="SRP68-RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.40">
        <property type="entry name" value="Signal recognition particle, SRP68 subunit, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026258">
        <property type="entry name" value="SRP68"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034652">
        <property type="entry name" value="SRP68-RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038253">
        <property type="entry name" value="SRP68_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16969">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038995">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="557"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9524666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="618" mass="68659" checksum="AC99F3A7B655D89E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E983</accession>
    <name>A0A9P6E983_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_819199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E983"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="170"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="143"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="37339" checksum="AAE0F728E52715CC" modified="2023-09-13" version="1">MSTQVNASSQSEIHKLKYEPDGSFKRPESSFRSMIEKGGKFEPDKDRYHLFVSYACPWAHRTLIVRKLKGLDDIIPVSIVSPRLGPDGWPFALVDEYPGATVDPLYGSRHVKDLYFRADLNYTGRFTVPILWDKKTHTIVNNESSEIIRIFNTAFNDFLPDNKKVLDFYPEDSRPKIDELNEWIYSGINNGVYRAGLAITQEEYLKAVREVFESLDRVEKILEGKEYLLGDKLTEADIRLYVTIVRFDPVYHGHFKCNLRSIRDGYPKIDRWARKLYWTNAVFKDTTDFDHIKTHYYWSHTIINPNRIVPVGPEPDIRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9A1</accession>
    <name>A0A9P6E9A1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157893">
        <property type="protein sequence ID" value="KAF9524815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9A1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="236" mass="25865" checksum="58BC6DCE2F264DA8" modified="2023-09-13" version="1">MAITASNVACGSFSGSASPQGIFPSTFNLFSPWLQNLASPILASRGNTLLGCQHQPSKDISNLTASSRPLVTKQKASGRRATATARRSSNAIAPKSRYYVTDDKPIRSSNHLRREGAKIFTAPTNALRREDSFILVDHGSHFKMVKPGYARLHYQPTPDNVMSIAGYHAFAPVNVSREREVRRLARHLGGVPVQVPVASEDSNVKKGTKRVKFDRPEDDEPQTPRKRARVTPPPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9I8</accession>
    <name>A0A9P6E9I8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_860615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9I8"/>
    <dbReference type="OrthoDB" id="2690153at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="495"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9524863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="548" mass="60188" checksum="EE981C6497D95EFA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA85</accession>
    <name>A0A9P6EA85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_859972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA85"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF3">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="1">
        <location>
            <begin position="10"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="35728" checksum="5524AA979A9BAA1F" modified="2023-09-13" version="1">MDPANDLPKLSTCTTCRFKEDFSNYWTAVMFFKHRNGSYIRVPQMANQVTGNPSGGMTVYYFQPFNGETVTAFKKGFRMIVGDPMIRNNTFINPDSGEAKALSFRCFDANFSGPSAPYAPGNGFDTVDFPKQKCAGGIRANIYFPSCWDGVNLDSPNHHSHMAYPLGPPDQSDLYYFGGTCPASHPVRVPVIFMETMWDTRRFNDLEWPEDGSQPLVFSMGDPTGYGQHADYIFGWEGDSLQRAMDKCVGGSGVPEACKELTLNTDEEMNKCTQTPRVDEITEGQYLEALPGCNPIQDGPTPATAVAACTAISTTVGIPSAKATSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAL7</accession>
    <name>A0A9P6EAL7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA-capping enzyme subunit beta</fullName>
            <ecNumber evidence="8">3.6.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">mRNA 5'-triphosphate monophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_859447</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67004"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
            <dbReference type="EC" id="3.6.1.74"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:67005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the fungal TPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.74" evidence="8"/>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAL7"/>
    <dbReference type="OrthoDB" id="272147at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031533">
        <property type="term" value="C:mRNA capping enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140818">
        <property type="term" value="F:mRNA 5'-triphosphate monophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004651">
        <property type="term" value="F:polynucleotide 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07470">
        <property type="entry name" value="CYTH-like_mRNA_RTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.10">
        <property type="entry name" value="mRNA triphosphatase Cet1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040343">
        <property type="entry name" value="Cet1/Ctl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004206">
        <property type="entry name" value="mRNA_triPase_Cet1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037009">
        <property type="entry name" value="mRNA_triPase_Cet1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE CTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02940">
        <property type="entry name" value="mRNA_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="4 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="10">
        <location>
            <begin position="72"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="328" mass="36916" checksum="E376D2A364A9AA9C" modified="2023-09-13" version="1">MVVKSKRCDPATVSISPNHHASFSRPPRSDLSSIMKRVRRASSPSNERPNGSASPSSLPALSLSILGVEPLDEFIKEVADFVHHMIMTRGQEIPNAKVEVEAKIGVLRERSSGQRLSLPVLVETILAPGFSEVRFESNMSVHQHRHFNTLLNNLKTNPPLSHSPIDYSHLYLVDTFYPSENSEKVRVTRDEKTGTVLETMRKVRLGDLNIYSPKREADWRISVNLEIPTPHPLGATSHSRRKDRLSYSHEEFKIDLTQVTSTMSANAPPQILHELEIEIARPDLLMATALKRNEASASEHERSAFDELIRAFVNNARILVRNANDGWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAP6</accession>
    <name>A0A9P6EAP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAP6"/>
    <dbReference type="OrthoDB" id="5289249at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="1">
        <location>
            <begin position="47"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="30162" checksum="20825EFA7E7FCA1B" modified="2023-09-13" version="1">MTADSSNPSRKTTANEARRQKILASLRLPAGVKRCNFLLVNPCLAVNLKGVWVVDPSMQTFKDQFPAFMNSKGKTPSKDRKNLELETTHAIFADVFVLPTTPYKQVLSEKEQEAEESQRCTSISLKSSRNIQFRLHDASSEIKNEDRSPIVVAAAAENGRLRINLPRSFCGPLHLQCTGRVWYSAAVKAQITPLAEVDGHHLSFLGDFKPDLWYGWEEWKGDSFEGFAGRGDAVDVYFDTEDYIPNTDSNLNTRLPWVWAMHTLGLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAR1</accession>
    <name>A0A9P6EAR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAR1"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="75"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="623" mass="70082" checksum="EDC28CEC12CF0674" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAR6</accession>
    <name>A0A9P6EAR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_796198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAR6"/>
    <dbReference type="OrthoDB" id="2690153at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="61644" checksum="FA159EDA5D45C6BD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBC0</accession>
    <name>A0A9P6EBC0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_817267</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBC0"/>
    <dbReference type="OrthoDB" id="4215474at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF4">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="8">
        <location>
            <begin position="45"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9526256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="485" mass="53671" checksum="3537D79437FFC814" modified="2023-09-13" version="1">MLARSRQIPSRLSHRAVSTKPSRYGQPTISSHPHLIRKDDLTPGIPASDYETRRRKLMEMLPEKSLVVSVAGPVKYMSSSAYKYRPSSNFWYLTGFEEPDSAVVLEKDSSSRGYKMTLFCSGTDSSKEKWDGANTSLADAKTIFAAEESLSISSLSSHLNSLLSSASHVFFDPPTPRPPTRNKTKRLLRYLSGPSDTEKELLEDLPSSMRRPLAPLLGKLRLVKTEAELGVMRAAADISARAHTKTMRFTEPGMSEHAVTAHFEYLCAREGSQRPAYVPVVASGPNSLILHYTRNNQIIEDGELVLVDAGCEFNGYASDITRTYPANGTFTAPQRDIYNAVLSAQKEMIKICTERAGHSLQELHRQSCRALQIELKQVGFSCSEGDLERVLYPHYLGHPIGIDLHESTYLDRSAPLKAGMVITIEPGLYIPPISNFPRHFHNIGVRIEDEVVVGTEHASILSVSAPKEIDDIEGACQGLLGLKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBN9</accession>
    <name>A0A9P6EBN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Topoisomerase II-associated protein PAT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_870651</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBN9"/>
    <dbReference type="OrthoDB" id="74835at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="9">
        <location>
            <begin position="30"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="943" mass="107817" checksum="4E73716E0D12CF63" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBS0</accession>
    <name>A0A9P6EBS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YcaC amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_858380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBS0"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053152">
        <property type="entry name" value="Hydrolase_YcaC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43559">
        <property type="entry name" value="HYDROLASE YCAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43559:SF3">
        <property type="entry name" value="HYDROLASE YCAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040115076" evidence="2">
        <location>
            <begin position="18"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="35"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="240" mass="26130" checksum="F8B0A74739942191" modified="2023-09-13" version="1">MAKFGLIGLCLLNAVYATLALASNFTYERIDKNNTVLLVVDHQVGLFQLVRDFQADEFRNNILAHAAIAKVFNLPTVLTTSAETGPNGPLPKEIVEMHSDAPLIKRNGEVNAWDNKDFRDAVQATGKKQVILAGITTDVCTTFLALSLVAEGYTVYANADASGAMSKRIADDANDRMRAAGVHVYSGFAVACDLMRDWRNTPGSVELLPYFDKYLAQYAYLARGHDAAVDRGTLLPGEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBX5</accession>
    <name>A0A9P6EBX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_837731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBX5"/>
    <dbReference type="OrthoDB" id="3066004at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="287"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="201"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="461" mass="52032" checksum="CE0B3D82F4811FEE" modified="2023-09-13" version="1">MSKVKKAFEGITKLEPDGSNWSIFITCVKRATLSLGGNYSDLLSSPKKILTLDNIQHDQELLHAITLLLPDSIFHRYMHKTHTYEVISALEDDYNISNAISEARTNSHLFTIKCHDESKLNTHLDTLLKIREDLQRTSQDVTDSQFIDAIIASVPQRLAELASALKTQHKVHNKFFAQDEDSKRELKIADLIRCLRSEVVGAKAKSSTPSHQYPNSANYTNHRNNGNNGRGQGRGRGNYPNSQSRDTYQHPNASQSHPNTNNSSHQQSHQHNHNNNQFTRNINSDICSNCGGTGHWSRVCPSEQRPQANSAEATPPTSTPDNLPQSDQTTSHTTTSLFAVPKTDEFSNIEESWHAFPDNEKSLNDAIWEATRPPDIDISDLLDQPRPEQEEIISSSITPGIPHIYTHGIVIRTYLPALKWPSANFAKELVEIEEEYYLEKQPADSANRLFQLRDEIFEIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBX9</accession>
    <name>A0A9P6EBX9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBX9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040193607" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9971" checksum="10B161010DB0810C" modified="2023-09-13" version="1">MMDWITWMIWICWGSPSHSSKPSRTAKIVGMCLPAFKIGSRMMDDPLAQHIERSINDPRVSLQKGSGWCNWLTERMNSRPQRLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC22</accession>
    <name>A0A9P6EC22_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_495890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC22"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21075">
        <property type="entry name" value="DBD_XPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="21269" checksum="196D8956F2CCDFE9" modified="2023-09-13" version="1">MANTLATRLQNRTIQTAILFEKGTNRLIFGEFKILEKDLQSLPTKKITKTRAKMLYYLSRNEVMALPMAGYSPRRRRDVGGVNPVTRLYYERDVEAAALKKFGGVKRFVNFLITKRREWRPLSGKQFSKYPKSYQELFLEALRKDQMRDAVLKSKRQRTRAEAASVCLEDSDVGEPSSRLLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECP1</accession>
    <name>A0A9P6ECP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECP1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="20298" checksum="A65D48CA4FAB63AD" modified="2023-09-13" version="1">MLKPLPQYHLRDTPAEFLKSCQLIPLPVSNDSLVTSSTNKLNHLISQPRTVTYRPPHIMDGRGTVEPAHWMVGSIAIWSEEEMLGKDGERGFVLVRRIDYDSCHQDLQAHAHPQLMQNPPPQGLRTSDDEAEPLTQWDIQFYDCVVKHLSARGPISDAEWILWTEMGWSVDDCVFIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECX1</accession>
    <name>A0A9P6ECX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_884677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECX1"/>
    <dbReference type="OrthoDB" id="1001765at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040217477" evidence="2">
        <location>
            <begin position="19"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="394" mass="39910" checksum="7C58DD11407D5839" modified="2023-09-13" version="1">MLFTSSLVSLLAAASVSALPALTKRAAADILVFKFADVLEQLESQFYSQALAKFKDSDFAAAGFGSSQVLIEQFQVIQADEDTHSKTLQAALKSFGQEPITSCKFNFESALKDVGTMAATARIVESVGVSAYLGAASLLTDPRILTSAGSILTTEARHQTFLNMISPTGTTIPNAFDFALTPSEVLTLALPFVDPSSPCDTGVKPNPILSVTNAGTIGVGTKLTFASDALNSTVDQSKLFCQMLVGGVVSTISLPLSECAPPAGINGPVAIWITSDPQPLLNDVTDRATTQIVAGPLMTYIDTQPQLVNQLIRASGGAVAATSTSTTTISPAQASSIIVNAPAAGPPASGAAPVASSSPAASGSAAPAASTASPSGPSADGAITVMGMANVPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECY0</accession>
    <name>A0A9P6ECY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_836884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECY0"/>
    <dbReference type="OrthoDB" id="2628807at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="235" mass="26341" checksum="407E1901E828D2C5" modified="2023-09-13" version="1">MCILYSARLGAIKWINGKTAEDRERFKSLVTARRSCQSSKSASGPLPQNLATDNCFLYDFVDKSLERKTANSPDPQQALVETLGLLDEVLNTSEEEQIGVKPRKDDKYTLVKSILDANYTIQIWLTSRSRRELCLDFVSAASQEPINTPTGVELWMSPCSSLPSVKMYTMEEIIAPLMPDFKVPVGEKHLLVEKQTIRVRRPGKEDIALQVPARPLPPPIVKNTAQVIEFSYSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDE7</accession>
    <name>A0A9P6EDE7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_429245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDE7"/>
    <dbReference type="OrthoDB" id="3238562at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="314" mass="34984" checksum="F1C280D3816A8EFC" modified="2023-09-13" version="1">MQSFFKDFMDGLRGSSPANNYRLVATLAEPEGAINALAFNPTGTSLASDGDDETVRIWDLASFKCVQALSDIEKQWGQITVLKFAQMGPDVSTEWLCFGTGFGMFVVYRRARKSTYFVELLRLKVFTSGDSVESFSFNPHFRRLAVGSHNGTLKVFELEGNGRDLTLLWDDRYDDMIIQSLVFVDQGEHLNIYIMASGDVICRNTDTGEQVYAKRLQSPIGHAEVHHPTVAVVIENMTNGFDLYPFNKPTPSRNFPVETNRLFIKSAVFAENGKIIVTGSDHGKVYIFGTTSSTALQVLKHGGREQLVQVVEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDH2</accession>
    <name>A0A9P6EDH2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDH2"/>
    <dbReference type="OrthoDB" id="3249923at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="816" mass="90452" checksum="96FC1626748DB3E7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDS0</accession>
    <name>A0A9P6EDS0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_935966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDS0"/>
    <dbReference type="OrthoDB" id="3223377at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="149"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="30097" checksum="C9CCBEF3916638CC" modified="2023-09-13" version="1" fragment="single">LIGYFLNWALFGVLSMQIYVYYLAFPHDRFWSYSIYLLETIQTIMLTQSAFRMFAQGFGNLLYLDNFGTIWFSVPILSGIVAFMAQTLYAYRIKVLSRSSIIASVVFLLAVIQLGGGIASGIISKRAVFESKFIGAELYITTGIWNGCSALCDILIAACMTFYLVREDTGVTETRRMVRKIVRLAIETGSLTAIVALMNFVLTLVPGHLTYYTATASVVGKLYSNSLMAIFNSRMRLKPEGSKPPISVEFSGIAFGHPQAGSHESNTTNDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE62</accession>
    <name>A0A9P6EE62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_767794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE62"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01250">
        <property type="entry name" value="pro_imino_pep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="38"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="309" mass="34251" checksum="78BA30BED82F477F" modified="2023-09-13" version="1">MATAQVLEGEAEFQVPGVNITCKTWYKVIGDLKSHSRPLVALHGGPGVTSEYLEILTDITNPRSSALVVYDQIGNGRSTHLPEKIGDDSFWTEKLFLDELDNVLNHLGIQDNYDLLGHSWGGMLGARHAVQGPSGLKQLVLMSTPSDVPTLWTQAQQVWLSQLPQETQEILIQSELNGTTNSQEYQDAVAYYRSLHLCTIDPMPAAIAAGFEAINKDPTVYLTTFGPTFFNVTGSFKNWSILSEASAIRVPTLVTNGKVDEVAESVVQPFLKEIPTVKWVQFEHSSHMAHYEERERFMEVVGEFLGPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EER9</accession>
    <name>A0A9P6EER9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbohydrate-binding module family 13 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_793058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EER9"/>
    <dbReference type="OrthoDB" id="9986966at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="152" mass="16559" checksum="4D9303BE996ECE62" modified="2023-09-13" version="1">MVTPTVGQWYRLTNAFTGTNLALNVVNDAGTASSGTIQMAAPGNFSGQFWRLEHNPSTSTSTYALYTLFLGESKRLDVFGDDATKPHLANAGNYSGQIWTISPWGDGTWKLTNAYSGSNMNLDTYSDTKVPFMGAPDHTGQHWTFTPIDPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF50</accession>
    <name>A0A9P6EF50_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U4/U6 snRNA-associated-splicing factor PRP24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_934295</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a recycling factor of the spliceosome, a machinery that forms on each precursor-messenger RNA (pre-mRNA) and catalyzes the removal of introns. Chaperones the re-annealing of U4 and U6 snRNAs (small nuclear RNAs) released from previous rounds of splicing, an initial step in reforming the U4/U6-U5 tri-snRNP (small nuclear ribonucleoprotein) that can reassemble into another spliceosome complex; this step involves binding U6 and facilitating the unwinding of the U6 internal stem loop, followed by base-pairing of U6 to U4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF50"/>
    <dbReference type="OrthoDB" id="360390at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12296">
        <property type="entry name" value="RRM1_Prp24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12297">
        <property type="entry name" value="RRM2_Prp24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000365">
        <property type="entry name" value="U4/U6 snRNA-associated-splicing factor PRP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034397">
        <property type="entry name" value="Prp24_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034398">
        <property type="entry name" value="Prp24_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="642"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="716"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="807"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="904"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="607"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="981"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="522"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="985"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00093627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9527604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1059" mass="118033" checksum="FF62E042D472F020" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF93</accession>
    <name>A0A9P6EF93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease H1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF93"/>
    <dbReference type="OrthoDB" id="3270804at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H1 N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="594" mass="63854" checksum="C959C9FFC9EFE844" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFV1</accession>
    <name>A0A9P6EFV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_835981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFV1"/>
    <dbReference type="OrthoDB" id="2668396at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="359" mass="37955" checksum="83653424EB98ACCE" modified="2023-09-13" version="1">MGSCLGLCSFFTKFSLPPPPPASLLVVCVVYAKYQHPQHPHIHAPFAKLQFAPREELSPPPPTFKYQLEQRRYGSSSSPPSPSSWYGGVEEDGSQLASWVGYPNFVSQPWSSSIRSKNPPPFIKFDPFADEPLVPAASAPSPGAAARSADAAVLNTGLSTLDAAPIEIQRYTSPSASSRRIIASQQPPAHSFNNNNTAFGPLNGGNGPASSLRYAGPIGSSHSPSSPSASLSSSVSAPVSRASSPIPSMRSMTPTPRASSGPSALGGPNVSKLVAGIMLNRVAVGKPMRRRAAPVTNSRQYIKSGLSSVDIDMIYVGFRGSTAYAHRPNLGVRARHAPFNQSVTSVGCNRPSFPRSDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGY9</accession>
    <name>A0A9P6EGY9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_315100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGY9"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="532" mass="56790" checksum="077546F1B32E8A0C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH27</accession>
    <name>A0A9P6EH27_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_813344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH27"/>
    <dbReference type="OrthoDB" id="3250110at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="38366" checksum="005C697656E29C26" modified="2023-09-13" version="1">MLSAFKIKEYDLQPIFEQWKDAPTFNNNPKKDLPVEEWLEKIREGCVERGVPEEYWYKVAQHFMGPRAKARLDELKQVISKVHGGKYRWTWKKFKVAMLNMGWTIDKDQKETIKVQGRSSGMWFSRKKDTDTASVKDLPQDPPAASSSSSQRTSQSKSRPSPTRSIKVTKKPLVQEPEEDTSSKKSSKGKESTEPRGRPMRAASVSGFWPGKLGNSSKDDSKTPQRPGHQKARSDTAVVLAKRRSASPAESTHSASEVVTKAEAPAWLLNACTALEFITSEHPKAMSVISAILITAGSIPAIPAIAAGAGGTILASGAVHAIGAIAVAAGQALGAGVAAQKNQQPAGVASITEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHE6</accession>
    <name>A0A9P6EHE6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_789441</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHE6"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9529688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="191" mass="20289" checksum="22961F9EB01B7F13" modified="2023-09-13" version="1">MSGVNPSTSHLPGTVPLWAAGKEPLPPGLTEEDRPMWEQNKKMEKFMAAGIESCPAKTLLAGGAGFGIGAFFSLMSASFAYEDPYLRQQTRPEIGNAQKARQIFKEMGKGMYSSGKSFGKIGALFAGVECIIESYRAKNDIYNSVSAGFFAGGILARNSGPKGAISGGLAFAAFSAAIDLLFIRREASDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHR6</accession>
    <name>A0A9P6EHR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_893695</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHR6"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04701">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="246"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="379" mass="40022" checksum="EFC60C2A9107FDEE" modified="2023-09-13" version="1">MANISEKNLIPIDKRALSTKPFTLVVHGGAGTMSKDGSTPEQRAKYRAGLSAALLAGHLVLKDGGTAMDAAVAAVTVLEDNPLFNAGKGAVFNVAGKNELEASIMVSKPPASHPAIPDTRRGLGLTLLTQTKNPSHLARALYLNPTSVPHTFISGETAEFLGQALGEELVDPSYFYTEHRWREHRRGLGLPEEPLPQTLDATPLKSSDTPLDSYPTGTVGAVALDVHGCISSVTSTGGTTNKLVGRIGDTPLMGGGYWAEEWNVPPSKSVLKRLWRRCVGSKDTSRAVGVSGTGTGDYFIRQATAVTIVHRVQFKKESLKTAAEGTVKDLAKLGGSGGVIALDKKGNVSLPLNSSGMYRGVIKKDGIPKTAIFAEDELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHT0</accession>
    <name>A0A9P6EHT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioesterase/thiol ester dehydrase-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_906436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHT0"/>
    <dbReference type="OrthoDB" id="5538558at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF39">
        <property type="entry name" value="THIOESTERASE_THIOL ESTER DEHYDRASE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="241" mass="27331" checksum="FBD0C81DA2E1DA7D" modified="2023-09-13" version="1">MNPSKGMLRLTSPRLFRTSYHAARKNSTISALQAAFRDPSSPYYLAPGERGPEDPNSPPVESVLNKAASEAMETLVDPLRAAEARLEKRGFDPKSFWEQRIVWGDHDSFQHVNNVRYVRFFESARIKWMMSVGEILGGPQRARDMLDGRGISLILKSIEVQFRRPVTFPDTLLIGYKVLPTPEGHTDLATFFVKASAYSLDQKAFVAHSKEALVWYDYDKLKKTDPGEDAMKLLLTKTHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EID2</accession>
    <name>A0A9P6EID2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Delta(14)-sterol reductase ERG24</fullName>
            <ecNumber evidence="3">1.3.1.70</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">C-14 sterol reductase ERG24</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Sterol C14-reductase ERG24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_789694</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17813"/>
            <dbReference type="ChEBI" id="CHEBI:18364"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.70"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:18563"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="16">Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.70" evidence="3"/>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EID2"/>
    <dbReference type="OrthoDB" id="10262235at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050613">
        <property type="term" value="F:Delta14-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1630:FF:000009">
        <property type="entry name" value="C-14 sterol reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF52">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE TM7SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00052254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00060638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00074394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00077841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00083315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9529514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="48654" checksum="F761B87F5695831F" modified="2023-09-13" version="1">MSSELNPRTKHYEFLGPPGAFLISIGIPAVTYALYFGCSEVTGGCPPQINGDHVVHALTDATWWKSLWDTQAATAYFAWYAFCVVAWAILPGDLVAGTKLRNGGRKKYKINAFSTFLLALGATTGYIMRYGPESFTFIYHKWVGLVTAAILMSLIQATYCYASSFKSGALLALGGNSGNILYDWYIGRELNPSIGSLELKSFNELRPGLILWVLINISMVCEQAVRRGGFRNVTDSMWLVLAFHSWYVADGLYNEPALFTTMDIVTDGFGFMLAVGDLVVVPFTYTVQSRYLAFHPVELGPFWTIGILAFKFVGYYIFRSSNGEKNDFRNGKNPKNLTYMETKRGTKLLTSGWWGWSRHPNYFGDWMMGISWCLPTGANTPITYYYALYFAILLIHRQLRDEEACQEKYGDDWKRYKKLVPYRIIPYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIS9</accession>
    <name>A0A9P6EIS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIS9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="35764" checksum="A1CDED317E74E5CB" modified="2023-09-13" version="1">MGKKKSKKADESETEQKAKSKSGSKPKSSKTRQRSPSVAPPPEERRQSSRQKANKVAPIPTTKDTSKPSRKRANSEAAEGPSEHKNKKPKKPDGTRRIPSAIPAEDSDISMEDLAEKSQAPFQPPKKNVKVLEDFPTEDDKLTEEEDNDNMVEQSKEHDLTLLSKSKLKDTLSAERPSWGQSQHLGANAESKSEVLQKNTKDDNKKQNRKKKASSSGTSSESDSSSSDSTNSDSTNSDSSSSDSESSSSEKEATKPTLSKRAKNRLEEVPQWKPTKEQATKKSRTRSKSQKPKPDTGSDNEAPHPDNAKKAALLHINQANPQVPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJX2</accession>
    <name>A0A9P6EJX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_905548</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJX2"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000268">
        <property type="entry name" value="ATPase 4 plasma membrane-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000004">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000005">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="698"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="726"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="762"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="809"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="841"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="64"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9530294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="991" mass="107923" checksum="BA9ACC3682A119C9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK79</accession>
    <name>A0A9P6EK79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protoglobin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_724197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK79"/>
    <dbReference type="OrthoDB" id="10027058at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin-sensor" evidence="1">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="193" mass="21983" checksum="8AED576C1400BA81" modified="2023-09-13" version="1" fragment="single">HIERKDLYTNLKTRVSYLQSFLGWTEADGEALQAAAPYIAPLIPTVLEVVYTKLLTYDITARAFATRSTSYEGPMDEFPALDSPQIKYRKNFLKAYLKKLVTGDSTQPEFWEYLDKVGMMHTGMGRRHPLHVDYIHMNALLGYVNDIIVTAVLENEGLDLPTKTAVVRALGKVLWIQNDLFAKWYVTDGAEYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKG5</accession>
    <name>A0A9P6EKG5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_850439</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKG5"/>
    <dbReference type="OrthoDB" id="5957391at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="9">
        <location>
            <begin position="5"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="35461" checksum="CA9F05F6B471904A" modified="2023-09-13" version="1">MPHSHHSHSGQFCKHALGNLQEVVNEAIRQRFRVYGLTEHVPRYRHIDLYPEESGTPVDALSVQFINFVDEAHRLKHIHASSIALLVGLETEYITDDDLDQLGLLLSRLGPRVQYLVGSIHHVTGIPIDFDVPTYERALTNSSRDDEDPQTAFLSAYFDAQYRLMQRFKPEIVGHFDLCRLFCPGLQFRNYPEVWEKIERNIRFAVAYGALFEVNAAAFRKGWDSAYPAGDVVAAIHEAGGRFALSDDSHGPEQVGLNFHRLPAYFQAVGITELWYLAESETPNDAGRNVRPVRLDKDVLLDDFWDGGVPTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELF3</accession>
    <name>A0A9P6ELF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_761746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELF3"/>
    <dbReference type="OrthoDB" id="3133286at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="29424" checksum="3C20890874930024" modified="2023-09-13" version="1">MIANPDNSPSRLRPRHLVEPKPSYGSIVPPQTQCLLNIAGEIVDILQENGVDCVLFGGLACTLYGSERVPNDVDLLTFPLPHLDAEDVKKLISEASPGRFHLKPSRNKKATWKILQCILTEQEKLVLSSLSNSCKIDILTPGTKDLPRIPSNRIMYLDTYPVMQFPALLLHKLQAWDDRRKQVGYARQYQKRLLDLEDLDRLFKLGEYVTRLRSSKLWQDRGLFSEQFEEASKIRALELCESYPEFAGRFRSVRLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELQ5</accession>
    <name>A0A9P6ELQ5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation efflux protein transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_904789</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer with SLC30A5; form a functional zinc ion transmembrane transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELQ5"/>
    <dbReference type="OrthoDB" id="5382797at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052005">
        <property type="entry name" value="CDF_SLC30A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46531">
        <property type="entry name" value="ZINC TRANSPORTER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46531:SF1">
        <property type="entry name" value="ZINC TRANSPORTER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="532"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="569"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="13">
        <location>
            <begin position="414"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="105"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9531224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="709" mass="76610" checksum="81B64F125686D631" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELR0</accession>
    <name>A0A9P6ELR0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELR0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58841" checksum="440DA6B5E5A4FE66" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELU9</accession>
    <name>A0A9P6ELU9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_867528</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrion-specific ribosomal protein mS38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELU9"/>
    <dbReference type="OrthoDB" id="3268560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035">
        <property type="entry name" value="AURORA KINASE A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32035:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="COX24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="6">
        <location>
            <begin position="252"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="284" mass="30952" checksum="3EDA619FE65E7A5C" modified="2023-09-13" version="1">MSAFSRFVHIPAARRSYSYFSSRSGGGGRYFNSTKPPKPPVVAQGTASAANASSNGITDSSSESKNNDGVQTTAPPTNAGSLPSQTANSSLEAATGTGTDAFGSPFVAPAQLMSAKDFKMHHFFSLHRPLLLINQPTSLFRSVPDNHPLFNPLPLSEAEIERKIMQSQSGMAGPPHTTNYPSSTGPTSSDTAAYIDADAEAARQLTRALTMSKAGSTVSWETTLHALGLDLNKEADRVGLQQQFEKEWQDVMLDSTKRKRRKKMKKHKLKKRRRATRSERLRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENJ6</accession>
    <name>A0A9P6ENJ6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_847737</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the GAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENJ6"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="12529" checksum="60B961EEE06C11E4" modified="2023-09-13" version="1">MGPPDQVLEMGTFVHAVEDEMLCSSTMADKVPYFNAPIYLQNKSQIGKVDEILGPINEVFFSIKMGEGMIASSFKKGDKVYIGGDKLLPIERFLPKPKVAGGITSNPIVIYVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENK7</accession>
    <name>A0A9P6ENK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENK7"/>
    <dbReference type="OrthoDB" id="3160134at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046521">
        <property type="entry name" value="DUF6698"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20414">
        <property type="entry name" value="DUF6698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="39051" checksum="2A60B9ADBDC8B3A8" modified="2023-09-13" version="1">MPASPTSTSSPRSSSEPTTAMSLTSNEARLILLERQLQAEKERNASDSDSDTVGKKRKAKQPSTQWYGRGIPKLVALFGDLEAMLDDALKYELRDLGDTSQDDADFENKDAGEIEKIKNEQTRAYRNILAFCKLLPSFHKRFVDNPLEIKSICAQGATSARGDDISKLGKTIPIWINEQWRDATPLNVKDRNTRGLYHDITGMLLCPITLDWDDENLRAQLRNFSYEGNMYANHLLRCLYFNFKGNPQHPDKGFLKSALLVKTFKHIFTSPNSADDVSILVRNEAEAAPSGLENVPPPPKTRRTNKRKPKVRKAVSAKLQMTEVTPRSIAYTAVQVGVDMQICHSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENU1</accession>
    <name>A0A9P6ENU1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_874009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENU1"/>
    <dbReference type="OrthoDB" id="3253876at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="37183" checksum="9F73E3E941021433" modified="2023-09-13" version="1">MYAGYGSPSPLTNNPFLPNTGHQTSSRFPDISSINGNNSYGGGGGGGGWDNGSSSMMGGGGYPQQQQGMYQQQQQQPMQTGWGGSAQMGGGYMSPSGQGYSSPPPMNMGGGGGGNGFQPQSAFGQQLASAGPHLSGSSYTYLNAGGQQSLGGGGGGYGNPAQQQQQQLLSQFDPYSAIGQGWDPVANANNNAQSSTGMQQSMSTGSTQSNNSSYSSSSSSSAGYGTGPRGDSHPKDYIRVHKQQIESWDGYAWKQLLGCFEAMKAAWEARKAELTGRARELIAQGNMGMAYGPYYAQQLLKEAEGNFDSIAASVYQMQEVFQNYRQSGDLASKRRVREATNAALQGLPGWPQPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP62</accession>
    <name>A0A9P6EP62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP62"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="36323" checksum="DE4FB2ACE1C8E569" modified="2023-09-13" version="1">MEPRIRNKTTTSPTPTPSFSPMYKYYIFRYFYLRTTTTVSTLVNPAAKLCDVHLAVLDEVSKSGGSEAHQNIARLTLEIANQIEVLTQLGLISYFHNLLSQIALFCVYFLSLKGGKLVSLYWEIHQDSHLPILRHAAVVSLFWNLAWGFAQVFNRALKSICDLTKTYSLGCKRKFSQQISLHRDIREHLKTLEAMVHRFENHTLKAMSKSDLKRLLEHFQSERQPEEPSKSSAPIGSPDQCDGKFSLIFSDKDNAAESRASEHTVGQVSSGLSFLEGTNGATFAGNTTMTGSTSTSHVTLHAPNATSFTFYFGVGNPPSAPDHSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP93</accession>
    <name>A0A9P6EP93_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_807300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP93"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040247241" description="Amidophosphoribosyltransferase" evidence="12">
        <location>
            <begin position="17"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="13">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9532179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="546" mass="59102" checksum="D0C1AF2481E5F810" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPF0</accession>
    <name>A0A9P6EPF0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_579833</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPF0"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="402" mass="46353" checksum="5DE7EB7ED952B774" modified="2023-09-13" version="1">MLLSEFASQGAMHDSSARQPFPKCHPQTRLNVVDFFFHWITTPTTSKSVYWLYAPFGHGKSAVMQTLIDRLMTENFQHLVAGAFFFARGKPECNKVIYLLPTIAYQIAINIPGMREHITKAIQTDPKLLSRSMDVQLRSLIKDPLFRCVDGAHFKYPPTVFIDGLDECTSIEEQLSVLDLIIVVLQEFHIPLRFLVASRPEAHIRDRFAQPHFVDILEQIRLPDDQGEMIVCLKSKFDDICDRRARLMKVSNIQKPWPSEKEIKQLVVRSCGQYIFLDTITRFVDTERRDPAAQLKTVLYCLADSSLFSNMDTLYSLILEEAPHPHILKVVIDDLLYRRTHSVFSIPAIAEIWQFSKTDIQIVLDSLSAVVKEWEGRDLTFLSYVVSRVFGKRSSIWQILLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPN2</accession>
    <name>A0A9P6EPN2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_847077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPN2"/>
    <dbReference type="OrthoDB" id="3267648at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="414" mass="47478" checksum="792FA0E544BCD66F" modified="2023-09-13" version="1">MSISKVIKIAAFLPPEVITELNHLDPFISSNRYILKIDLEMDDISDRHVLEPIKNIETELAALQAEQSAHQIRATSITSEMDQGSGNNRVLRKIPRSRKARKELLIRRLCEIVAADRELPREARIDAIEIGPEPYRPYYQAIDGLSPKHVKLTAGFEGAVMFDDIESFFYPWDDIESAVISGEAEGWWLESFRTPKGETQNPDSTCAYPEFITRIKSLTLHYCEGFNFSARYLPVQMVNFKIVGIDALSTFCRAFERIPGLSERLQRLHLTSNRGCFEWVYFRQCLRECSSISYLFLALGDDEKYYNARPSPVRDNDTKLLSSFPPFVETLSFHCSTSHEMLVDLDSWIDATSQSGWLPQLKEITIQSNGPQLDRLPGEEIPKVSPERRNLFQRKIDRIYINLQSRSPPVVILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPN9</accession>
    <name>A0A9P6EPN9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPN9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="219" mass="24541" checksum="6A79B0C2E055F5AB" modified="2023-09-13" version="1">MSISRVLKTSLTFAPEIITKLKEPDPFVSSNRHILKINLRLDMNEVNDIREPDKDIDVALVALRTERSSHQVHATSIAEELDSGDSDPPITGIRRDGSRNPYGKAREELLVRRLCKIVAADRELHHEARIDAIELGPRPSRAYYLALGGLAPKHIVLSRGFEESLVVDPIESFFYPWDDIESAVIGDECHGWCMESFRAPKGETTAPGMNCAYPEFLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ08</accession>
    <name>A0A9P6EQ08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATPase, V0 complex, subunit E1/e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_844742</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ08"/>
    <dbReference type="OrthoDB" id="1508846at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040415464" evidence="10">
        <location>
            <begin position="23"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="69" mass="7516" checksum="421D6BF173EC8057" modified="2023-09-13" version="1">MPSTLPLIILFAVSAGLMTASALFTPKGPNQVTIRTGLMLTFACCYLIWAITYLAQLHPLMVPQHVAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ61</accession>
    <name>A0A9P6EQ61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_846521</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ61"/>
    <dbReference type="OrthoDB" id="3429912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="134"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="755"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="789"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="949" mass="104440" checksum="EE2A6A7C6B41B96D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ98</accession>
    <name>A0A9P6EQ98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_845925</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ98"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16657">
        <property type="entry name" value="RING-Ubox_UBE4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="12">
        <location>
            <begin position="1029"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1122" mass="125815" checksum="301F3A4FAC3559D3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQC6</accession>
    <name>A0A9P6EQC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_942859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQC6"/>
    <dbReference type="OrthoDB" id="2310204at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040224935" evidence="3">
        <location>
            <begin position="22"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="312" mass="33449" checksum="337474F1C9DAC6E7" modified="2023-09-13" version="1">MVSTPLSLSILLISTVPYCQAGSQSGSTEQRLPRSHWKRGQSSSSNSRNVPSEGYYDPRANGGLMLTKVPVTYPMGQGEPLNAIISGNSDAAVLKDQETQGGLRNYFLSLGFSGECLGQHSGEDQAADLGDGHGTKNETAVIRWNYGDPQLGSCKETVQGGNHFRYWVQDGPNTNSGAVFMAVSYEKPLNDGHDIIQNGYSLGRDWLVGNITNTTIPTANLTNGMNFSANSWSGGYEYQSDVRYITGLLDNTNDAINHNITVSGPGFNASDGFVAVIEVKLITKPPKSLAIITLPSLWQASIILGLLSLVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERD9</accession>
    <name>A0A9P6ERD9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_845316</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERD9"/>
    <dbReference type="OrthoDB" id="1660966at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000001">
        <property type="entry name" value="Pyridoxine biosynthesis protein PDX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003215">
        <property type="entry name" value="PRK04180.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00343">
        <property type="entry name" value="pyridoxal 5'-phosphate synthase lyase subunit PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="PdxS/SNZ N-terminal" evidence="12">
        <location>
            <begin position="51"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="8">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="279"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="338" mass="35552" checksum="3F172822AE3193A7" modified="2023-09-13" version="1">MSPDMSTPATSTAAPAALPTPPVPQGVGSAAAPTPLPLRSAKDSSNGIGTFGVKSGLAQMLKGGVIMDVINPEQARIAEEAGACAVMALERVPADIRREGGVARMSDPDMIKQIVAAVTIPVMAKARIGHFVEAQILQAIGVDYIDESEVLTPADDQYHINKHGFKVPFVCGARDLGEALRRISEGAAMIRTKGEAGTGNVVEAVRHQRAVMSQIRRASVMDDEELYAFAKEIQAPFHLLKETARLKRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGIFHSGDPAKRARAIVQSVTHYQNPKLLAEVSENLGPAMVGLTIDDNLKGGQFASRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERV8</accession>
    <name>A0A9P6ERV8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_756418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERV8"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="363" mass="39828" checksum="C1F8F6FA9530748C" modified="2023-09-13" version="1">MARSSSGIPLTPSGCRSASFTISRLLRFCFIFTTLFSTVSAQRKQPLVVVDPFKDPKNDVLNPLRYIPSNVLTAIAVSLILIVALLQTLWIFKWGAKWMMAMTIGAYCFALGIGFRFGLHSNPHSDGIYIAEYLFVTLSPCAFIAADYVLLGRLARHLDADKHLLISSRRLTAVFITSDVVTFLTQAAGGGITTSRNNLNNQRIGPKIFLAGLAAQLASFAAFSAVFAVFLYRIYTKEKPLLRIDGHKAWYSRWTALAGALVLSCIGILIRSCFRTAELSQGFGGALARSEGLFYGLDTLPLFIATAIYIPFWPGRFIDDHQPLRSPGIENTVTGNRRGSSDSVSRTMVELGQVGQKPTVEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUG3</accession>
    <name>A0A9P6EUG3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_841817</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUG3"/>
    <dbReference type="OrthoDB" id="77989at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="244"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="54065" checksum="73D8A16A5D2B80A5" modified="2023-09-13" version="1">MTSSSSLRDLYVDPNQAWAFLPPKASSSVPTPPAPIAGAAAEFPSSSTSKFNLPYEFNTSPYDDDGHINLPQLFRSFVTAGVLQYTSTAIVMPWEVGKLLLQVQWVPRDAGEPEQLSTEGVEDDNDDVLSDASGEDAYFADPHAPPSSRTPAPRARTDDQGYVIRRSVLEEGTRPEYIIPVGSADGVWGMMKRVGGFRAEGWIALWKGLLTACITEVLSDKMQPFINGFLQSLFFPSMSPFHRPPIILPVASHLITGFLLSPLDLVRTRLVIQSFTSRHRTYTGPIDAFHQILRDEGGLRGIYLHPHLLLPTLLDNALRPIVALALPGMLTTYFGWGHITEETHPIKWGMAELAGSCIGLLVTLPIETIRRRLQAQVRGSAKPVKTCVELRPAPYNGIVDAFWHILTEERSDLPITRSTRKKRRLSTKDKEDGEKAAEDSTSDEYQSWWSHTGLGQLYRGLGMRLGASAVVFVLAMVGGGEESADGGWAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI62</accession>
    <name>A0A9P6JI62_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_911547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157962">
        <property type="protein sequence ID" value="KAF9522076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI62"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040441260" evidence="2">
        <location>
            <begin position="21"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="256" mass="28214" checksum="9177862478298714" modified="2023-09-13" version="1">MVQFVKVAMVAALAATPILAIPLNARYEAKHPSASGAHHHHHQGHRAQIKAREPVDPKHAHVHTHTNQHAHAGHHHHSTIHAREPKHGRASIARAAGRFAGGVVSAYGREFDEVLEARGGTNIKSPIGKPVAKPAPKPSGPKRISTPHRREEFDEELEARGGSNIKSPIGKPAKPAPAPARPVAKPNKREISYLNARQSMKNIPKRPGQKRELYDDLTARGLKNVPGSKPLGHGKRELYDDLLEEREFEEFYDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JID9</accession>
    <name>A0A9P6JID9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphatidic acid phosphatase type 2/haloperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_777418</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157955">
        <property type="protein sequence ID" value="KAF9522212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JID9"/>
    <dbReference type="OrthoDB" id="8907274at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000017">
        <property type="entry name" value="Diacylglycerol pyrophosphate phosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="107"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="349" mass="38703" checksum="F5167734FC25DEA8" modified="2023-09-13" version="1">MVQFPFRATHPSPRGTVTNARRRRLLLSYLPDWILTIVLAAIFLSLDHIEGYRRVFSVTDTSLRHPYALHERIPSWALYIIAIIAPLVLMPIVNFLTVRSWWDLHNSQSLILAAALTGSFTQVVKITVGRPRPDLIDRCRPPAGTANPDFGLTSWTVCTQTDNGILRDGFRSFFSGHSSISFAGLGFLSFYLAGKLHLFDSRGHAGKAWLALSPFMAASLVAISRTMDYRHHWHDVLVGSLVGTVLAYFSYRMYYPSLAAPVCHRPYSPRIREEGASENGAHGSHLPMHQTEAAEYSGVRINDNDLEAAPGTVPKPDPGKLEDVWREGNAEESGGLNHGVKPPTGKHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JII9</accession>
    <name>A0A9P6JII9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JII9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="54" mass="6340" checksum="4AAED3897C503545" modified="2023-09-13" version="1" fragment="single">MCISPAGHVPKRQFHLVLFMVISLYVSRLIIQRSQGLNRTLLRREQRAFASTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIX5</accession>
    <name>A0A9P6JIX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA breaking-rejoining enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_864040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIX5"/>
    <dbReference type="OrthoDB" id="2678913at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052925">
        <property type="entry name" value="Phage_Integrase-like_Recomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605:SF3">
        <property type="entry name" value="P CELL-TYPE AGGLUTINATION PROTEIN MAP4-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34605">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9522736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="54877" checksum="922156AE5CA8C6AC" modified="2023-09-13" version="1" fragment="single">MCSPHMSTRSSIQPTPHQEANTLPRLSFFHQSTSLPSLGHSLSTSTLLTHLNTDTDLSQNQPIQQHYAIQVPKTPSIARVSTTNFRNLSSETTRGSNTSSKRFNAPLPTRNSVQGRPYPPHLPLKFSILRPHCPAQDRLAVWKPLQSRRSFSNSPSLIIDCEDSARISTVIEARWDKSTRETYGSGLLTFHSWCDSRNVPELEHCPVSHITLITFIASCSGSYSASALRNMVHGIHAWHTLHGQPWSVVRSELDAVLGGGGKLAPISSKKAPRPPVTVEIIKAVYQKLNLNTPLDAAVYACLTTIFWSTSRVGEFTLPSLKSFDSQLHIKRSNIRQGFDRNNLQVTIFHLPHTKCSPTGEDVYWASQSGVADPNAALNNHLLLNNPSNEEFLFSYSSNSGRHPLTRNCFLTRINNALSSSNLPPIQGHSLRIGSVLEYLLRGIPFDVVKSLGRWSSEAFTKYLREHAIVIAPYIQDSAFQERFLQYTMPPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ15</accession>
    <name>A0A9P6JJ15_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_864306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCC4/mau-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ15"/>
    <dbReference type="OrthoDB" id="5565328at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019440">
        <property type="entry name" value="MAU2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10345">
        <property type="entry name" value="Cohesin_load"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="564"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="645"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="588"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="646"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="853" mass="92745" checksum="6076F8DAA17523DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ93</accession>
    <name>A0A9P6JJ93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ93"/>
    <dbReference type="OrthoDB" id="3130687at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="42897" checksum="3EAC4BEFB81CC7CA" modified="2023-09-13" version="1">MFQKVIKRSKDLPIAVSVVSESRYWRGTRGDLLPVVEAIKSCITRVHSLDIALPTTLLGEFTGISAPMLLHFALDTIDQTDMWGNFGVQDIRSLTENVQGMCLRVWDMHHVALCSERVVELQVSALSPSCLLQILQDTPSLRKLTALQLCSADKFEDSSEDSNEDSDEDSEENSDSTKSSGHCYEDGTGLHAGDLLKKLTLPRLKSLTFPTAQEIDSEDFIDFLERSSFPLETLDLSAPDSLEDLEMILDLLPSLKTLNLDTMDDESLADVFEAVFAPELDNSALSKFSYEGRWMAEQPDWTFLQQCLRATPSLRHLDLTIYAYLRDVSMDQIWIDEDNVKAIRELRSEGRHIKVEIWASGNHFEDFVEASHSRPPLDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK34</accession>
    <name>A0A9P6JK34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_898426</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK34"/>
    <dbReference type="OrthoDB" id="1898734at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF2">
        <property type="entry name" value="PROLYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="63"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9523862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="454" mass="51683" checksum="70B7B559DF3D5E5F" modified="2023-09-13" version="1">MPGDLAGQETYFVKDGMKVIERFFVVPLNYAKPDEEKIRVFARHIIPKSKAKNAEDEKKLPFLVYLTGGPGFEVGLPTSAGYPGQIHDKGYQTLWIDQRGTGLSTSLSPDTLPPHVKTDEEIAEHLKHFRADNIVRDCEFIRKQLLGDREKSEDQKWTVLGQSFGGFCIVTYLSFHSEGLKEAFLTGGLAPLVDQPDIVYDALVQRVIKRNQVYYKKYPQDVQRVKQIVTFLEANEVVVPNNGHLTPHRFMQLGHDFGMSGGIDRVHQIVFRASSDLELFNKLSYKTLQTIQNSQPFDGNPLYAILHEPLYCQGQAAKWSAARVVEKHACFSWDKVKAQEESTPLYFTGEMIFPSMFDDYANLRPWKGAADILASDESWKPLYDKKQLEDNEVKVSTVTYLDDMYVDFGFAQQTANTIKNTEQYITNQLVHNGLGKDPADVMKTLFKLSEREFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK57</accession>
    <name>A0A9P6JK57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_689017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK57"/>
    <dbReference type="OrthoDB" id="61437at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="907"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1091"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1121" mass="123310" checksum="82C5724B9FADD411" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKS4</accession>
    <name>A0A9P6JKS4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_621605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKS4"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="91" mass="10305" checksum="C5AACAE994D184A5" modified="2023-09-13" version="1">MTVAEEPVKKLHIRVVFNHQTVDFMIKPNKPLAKVFDTFATKLNLDIGSLRFHAEEQRLYAEMTPEQAGLSDGDQIDVVLFQEGGSFKLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLS3</accession>
    <name>A0A9P6JLS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9525020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLS3"/>
    <dbReference type="OrthoDB" id="2367075at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="138" mass="15596" checksum="8EC29D65F49B8D62" modified="2023-09-13" version="1">MVSAEDLEDVLEILGISTFGSSDRLSYLPVGQWISGLKLAVRWAYDGLRDTAIFYLNQNQEFCSNPVQQILYGRDYGVEQWLIDGCSHFVLRSHGPREQEAIPLGMTTTIALYDMRESMSISGFNLKAAIKSTFEDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLV5</accession>
    <name>A0A9P6JLV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_565978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLV5"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="242" mass="27163" checksum="FB23B961C9606532" modified="2023-09-13" version="1">MIGLIEERQPLLTVAEAVVPLRSAYVWTCAKTWTSTHERDPQMRYLRDAHRPSPLACLSDTLTMTAILSLLTVKTVALAVHKGERFIIVDPPENGRIEHTPSIVDRVRNGLVFGLEMVLNRDLFFLIESRKRNEEAHKKVQSATKFVFGDRVKQMFYISIFAANMDTDIHNHAGALVDAVTGLADLVDQGIWVKSTSTAQTAFFRSHGFTTIAEVVLGDQNTKWHENPVIIDIMVREPRGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM57</accession>
    <name>A0A9P6JM57_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_837876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM57"/>
    <dbReference type="OrthoDB" id="3004867at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="44025" checksum="22880105AC17C9A9" modified="2023-09-13" version="1">MARNVTVGGANSSSILFNPVDCNTWNGGGWQTNPGKGASGAYKSCTPDGTATASAKLTFTGVAVYYQSIYFDNYSVIFSLDGVSSSNISLALPPGTRVSPNASKLMWFKEGLSNSDHTLEIFPGNNGRTLNIDAIVYTQADAGSISTQVPPSSSHAVSLGSTQPVPMAAAQIPAVTRNSQNIGLIVGTIFGVIAGIIFVVILFLMFRRQRELKADRRAIVQEPLPQTFSDRQFDSRLTSSRPGHAPIGGGDNEKAHTHTQQTEMSNWIQQSPPSSPEMATPVRPLPIIPKDTGRSSHMPMQDIREEDTRPLEWTSYNPSSTKTHRPHLSDDTNKSDWYAQSQTSLIRNANASTSGESPAAMALSGSGRQHLQNPFVTDQQPTRTSTVTTTSSRKLEPLRKGSQRSIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM92</accession>
    <name>A0A9P6JM92_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endosome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_505236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM92"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPRY" evidence="2">
        <location>
            <begin position="146"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="316" mass="34908" checksum="BC1F6658D7094FE5" modified="2023-09-13" version="1">MGFFTSLKDKLTEATHSSSSHHDEDQGSSMPPAWAPAPEISHQYGKWNEAPEEEYDAAEAFCSEYPVQPPRLLPSNAIDAITNLGCKAWGIEYPTSPRFAGTIRNPDDKKGSSAGVCTVQTNKKCKDTCLLSSLPILAGLYDIQGKTGVYFEVQIHRMDGIIAVGTACRPYPAWRLPGWNRLSAGFHLDDFRKFFEDPDGGRDYIPETNSSPLTSIKPQDTIGLGFIFSSGTLFYTYNGVRLPDAFQGIYLPRQEHDVFAAIGVEGECEFEVNFGGDVFRWKEANEWAWRVEGHVGKTNGSSQGGDDELPSYQALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMJ9</accession>
    <name>A0A9P6JMJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-thiolate peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HTP10</name>
        <name evidence="10" type="ORF">CPB83DRAFT_896350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMJ9"/>
    <dbReference type="OrthoDB" id="2542103at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.489.10:FF:000001">
        <property type="entry name" value="Aromatic peroxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF16">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040501589" evidence="8">
        <location>
            <begin position="24"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="68"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="41585" checksum="4891A38DEB6FE06F" modified="2023-09-13" version="1">MKSFAALSAILALAFTTNYQVSAFPAYASLAGLSEPELAAIIPTLHRREPQPLPLPQNDTSTKLVNDAAHPWMPLRQGDIRGPCPGLNTLASHGYLPRNGVASPNQIINAVQEGFNMEYNTAVFVTYAAHLVDGNLITDRLSIGGKTPLTGPDPAAPASVAGLSTHQVFEGDSSITRADAFFGNNHSFNETLFQQFVDFSNRFGGGKYNLTVAGELRYQRIQESIATNPNFTFISPRFFTAYAESTFPVNFFVDGRKNGTEEAGQLDMDAARSFFETSKFPEDFFRPAGPTGPKGINEVFKAHPVQPGKNMGTVNSYTVDPTSADLTKFCLLYENFVNQTIARLYPSPKGALRQALNVALEHMYKGMADPECTQLFPYGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMZ6</accession>
    <name>A0A9P6JMZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMZ6"/>
    <dbReference type="OrthoDB" id="3173702at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="449" mass="49558" checksum="2AA276DBE916D947" modified="2023-09-13" version="1">MSPDPLINALSDGLVELFLATLRHANSAAVKPVASPPPLYTPLYDKKSYPGLGLPSYSGVDRKPTELEADFHTLADVAKKHERNNPGDIHDRLVESLKQVNAEETLKNLTNHILELKVSFGKISVALGQVDDKNYRKKSDSSTNEERIEKFRPTWDKIHKDFDSLIWASQDVAMDAATHAKVFHDILLPILKDNTLPLSRKKEELRSYILNLEKSEAVAEKMTNSFTALPHRIRAVKIRVGVALKAVGEHQDTRIRDLNKEIDELELRIRKYSNLGRTAMWVGAGGAAAMGVGVLLSLTGVLAPFAIFSFWAGKTAMKGAVIGKAATSGLEYAAEKERDRKIYERDQLIKARTNLDLNGIQAQVDQAFAESEGLCSRLNAIGTVWGVIRTESQLILDSMIKAGNAKTRWSFEPLTEKVCGNAYAQLGEVLVSYSQSITLLSQLCPTIGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNE4</accession>
    <name>A0A9P6JNE4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_884696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNE4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="24478" checksum="23035C099A3C5341" modified="2023-09-13" version="1">MIYLESLCIEAQRDLDVLEEALFKRDTRDRGISLRRLKKLVVSIGADNSLKAADKSLQNILGNCADTLEELVVLPSPHAFFKTFDEPLDLTKLKSLKHFNAFLELSNYGLSDDFYDTIPCYMVESDDILSSLDTLPNLLIGGRFPMLRILNLYISFISDFRIIEDLKYSAFASRLQSKSGFTLQIQKLDQERSPLLLFASNPSWTRIKYRPQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP00</accession>
    <name>A0A9P6JP00_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_884483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP00"/>
    <dbReference type="OrthoDB" id="3261276at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040370850" evidence="2">
        <location>
            <begin position="31"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="625" mass="66434" checksum="337D13300E2069EB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPY0</accession>
    <name>A0A9P6JPY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavoprotein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPY0"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="21861" checksum="01BD7B40BA811508" modified="2023-09-13" version="1">MSQPKIAIIIYSMYGHIAKLAEAEKKGIEAKGGSATIFQVPETLPAEVLTKMHAPAKGDYPIATPQTLVDYDAYLLGVPTRYGNMPAQWKTFWDATGQLWANGTLVGKHAGIFVSTAGPGGGQEMTALSFISTFTHHGILFVPFGYATGYQANISVTEAHGGSPWGPGTYTDSNGSRQPSERELKITEAHGAHFLNIVSRVHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQX5</accession>
    <name>A0A9P6JQX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_893940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQX5"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="34793" checksum="27FFC6A1F28631F3" modified="2023-09-13" version="1">MALNTVDPLLYIPVDREGKMVVYHYVLVGTLAVLFFDLLDSSIEDYTLFTQKRWTLITLLYATSRSSTVAFVLLDVLSQLALPGKCQFWRMSSTVFFILAHTSTSAIFLVRASVVYNEVRRAIAFFAVAWVVAACSFIVTLSKTTSKHLGPSHFCLTSINEQYMMVAIFVQCAYDTLLCGAITYKLAVESRDTSTPGKWRPWRLPVTMNFHRLEQRFLQDSQTFYLLTICFKIPEIIIYFVLAATHGVPSAPVMVIMAFPDTAITSIIAGRVYRKMKLGRPGLMEGAITMETLDLDRLSVTSITTGSQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQY7</accession>
    <name>A0A9P6JQY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_187932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQY7"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="107" mass="12226" checksum="6A1E2FD0B90B963E" modified="2023-09-13" version="1">MDDYRLLCVTHDFPFIRLIPYVTSIEDPSILSGTLRSTLDVFDEYEDAEICEASRRVHLIPSENQLPEAADTINGNILHELDSRSRGLAIFFTRGLSFQIKDNCLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR63</accession>
    <name>A0A9P6JR63_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_812029</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR63"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="21140" checksum="5F9B67BB616FE7B5" modified="2023-09-13" version="1">MLKDELINLLVAGRDTTASTLTFSLYMLAEHPAIEARLRREVLEAVGPNRQPTADDFRGMKFMRAFLNEVLRLYPSVPINNRTASQPAVWTSKTPGSKPYYVPAGVRIIYSVLLMHRRTDLWGPDALEFDPDRFLDERVQKYLTPNPYTFLPFNAGPRICLGQQSYCLCEAFIGYSDTNLLASKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSD4</accession>
    <name>A0A9P6JSD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSD4"/>
    <dbReference type="OrthoDB" id="3032312at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="311" mass="34204" checksum="456189E3173F9677" modified="2023-09-13" version="1">MASYPAAFHNLSPTSQMSTAPHSSRYPADMSLDYSYTYFSGGAESSATYYSPASTSSQSISSDLPDLLYDYDLGTPPSATSSDLLYTPPQEWHPASNPPARTTVNAQSHSPHSWHSTIPGPGHVYGAPDKCDYHPPPGTENIPGGQNDMFDGHQKHKTTMYPHDLLLTQPLSRPPSNTVAPTAPHLNPPTSVNPGLYSQVPLELHQPRPSRRIPIVNLDRLASVCEYNRSNKRGSRAPENCLSSLDSTNTRSRPFQWPTQFRTPSQRSRLHIPQLVHSNAQQPTYHSSSTFQQSEVILCGCGCMESFIFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT49</accession>
    <name>A0A9P6JT49_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_849547</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT49"/>
    <dbReference type="OrthoDB" id="6339427at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005366">
        <property type="term" value="F:myo-inositol:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904679">
        <property type="term" value="P:myo-inositol import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000073">
        <property type="entry name" value="MFS myo-inositol transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="70"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="537"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9531200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="564" mass="61005" checksum="054A95C84194639F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTZ3</accession>
    <name>A0A9P6JTZ3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phytase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTZ3"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF42">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="646" mass="71298" checksum="77091635C7CC3152" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU72</accession>
    <name>A0A9P6JU72_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_804910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU72"/>
    <dbReference type="OrthoDB" id="3981028at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="515" mass="55591" checksum="A14E9076C1562F0C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUD3</accession>
    <name>A0A9P6JUD3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Orm1 type endoplasmic reticulum protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_843713</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUD3"/>
    <dbReference type="OrthoDB" id="1932233at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007203">
        <property type="entry name" value="ORMDL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12665">
        <property type="entry name" value="ORMDL PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04061">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9534122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="233" mass="25915" checksum="F255C006C35A9E74" modified="2023-09-13" version="1">MSRTGIKLPALDLSAAKPLTGLRSRGRSSSIVKVEHVGDRSVEEFVDRGAYSNINADWVNSKGAWMIHVVLIIFGKIIIDTLPGMTQQISWTLVNLFYLAISYLMFHWVTGIPFGSDLHGGAYDDLSLWEQIDDGAQYTPAKKWLFSVPIGLFLASTHYTNYNPWLFAINLTALVVVLIPKLPQLHRQRVRFLTDNASGMSTPTTQSFPNSGTSTPPISRMPTAVHLTEAHFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUK9</accession>
    <name>A0A9P6JUK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_628023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUK9"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="92" mass="10137" checksum="855D5A61ACBD2D09" modified="2023-09-13" version="1">MWKPATRQLTGTNDVPLGNRRRFGPAPTEDTPAPQLAQPSPSAYPRPRDQDDGQKRGRDDSPVNGDTKSKPLMLKQPDILRLCCTAQGLVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUZ4</accession>
    <name>A0A9P6JUZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_889941</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUZ4"/>
    <dbReference type="OrthoDB" id="3763at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.430:FF:000002">
        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="12">
        <location>
            <begin position="42"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="11">
        <location>
            <begin position="228"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="523"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="60986" checksum="EC8CF783E311785E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV68</accession>
    <name>A0A9P6JV68_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit WBP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_757256</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV68"/>
    <dbReference type="OrthoDB" id="29105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040541957" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1" evidence="8">
        <location>
            <begin position="21"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="291"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9533658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="449" mass="49697" checksum="02D9D7182BE40BBC" modified="2023-09-13" version="1">MFPLKKLIILAVGLFGLTSAKSSTGNSVLVVVEAAQKDDFSIFFDGMRDQGYELTFRGPKEEAPLLIEYDEPKFAHVIVLASDTKNFAKDITPQSLISLTHLKTNLILGLSTKQTPLTSLASEFGLIPPPPGTPLISYFPKREEPSTLIPITPKVQDSAVLQSRNNHPIWFSGSPHALGNNPLLVPILRAPVESFASEVDGGSPDAIVDSADKGGEGFWAGSQLGVVTGFQTLDGARVTWVGGVDVFSDEYIQKQSSKRRGVQSGNRQFAHDVVAWTFQESLVLRIDKVEHHRVNTTEPRDQYTIKDQLEFNAYISKFNPKNRKWEPFSALKDLQLEFTMLDPHIRTSLPAVSGTPGKYSANFRAPDRHGVFKFVVDYKRKGWTALHSSTTVAVVPPRHDGYPRFLSAAWPYYAGAISTSVGFFLFSAFWLAGEVRESWKRPGKASKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV78</accession>
    <name>A0A9P6JV78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_843535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV78"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="15473" checksum="699ADE54610F201C" modified="2023-09-13" version="1">MSHRGEEVHPWDISRSFPTELAVTTQKSPKLLYTFPPEILSLIFGYTLPTHDDIEDWMFFLPIHLALGKICSYWRRVVWSTPRLWSIIAIYYDSEDYEPDVPLTLVDRWLTQSKERPLIVWIAVEYAVDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVW2</accession>
    <name>A0A9P6JVW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_803228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVW2"/>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="232"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="471"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="344"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="57978" checksum="2197E992C1C5F532" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3C5</accession>
    <name>A0A9P6E3C5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157993">
        <property type="protein sequence ID" value="KAF9521751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3C5"/>
    <dbReference type="OrthoDB" id="3067340at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="318" mass="35983" checksum="9A7A2CFD1CB317AD" modified="2023-09-13" version="1">MPIRIMGLDLLRRLNMWLSYLIRHLEPGMVTNRHLLDNTAPNPKNLPARITDTMPQIPTQHSPQVARLMTIPANRKVLDGCRHSLKRRPRVKHLVNDVDVLLFQPQPLRGKRSDRPPACQTDVSGALMDICSRFHMGRVDDFRDFLEQTGSVVSGSNALLAIHPGMFKRRILRYTRPGTVNVLWLLTSRAEAICELKDHGEFHSTIVMNYFAHFEAVCMYPGLTPAKTGLINTSNLRDEHYYAKYGLRGFALTSKQIDQGKHTCTMNLTVLPQSDPSTTMHPSSSHSMTSKDTFPITKVIYVGDSTTTHEEQMAEGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3I3</accession>
    <name>A0A9P6E3I3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157984">
        <property type="protein sequence ID" value="KAF9521835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3I3"/>
    <dbReference type="OrthoDB" id="3256444at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="20932" checksum="F77A918A83236952" modified="2023-09-13" version="1">MTCGFVNRHRDLRMAFGKFALKMYPLEREKLKTTANDRTRVLAGAALTITVESLEYHASHWDHSKKPKLLNNFVVTASTYYDSAGPSPACDLHQCLQSYIGGLNTQNAGSRFGSKSRKSQKPPTAAQTQTKSDLLPSVQPPRAGPSKLPGITNGTNVWKRACVVASNTNAYFGVTGHWIEELSPGEWIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3M0</accession>
    <name>A0A9P6E3M0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_777975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157980">
        <property type="protein sequence ID" value="KAF9521863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3M0"/>
    <dbReference type="OrthoDB" id="2629491at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="7710" checksum="159C986343DA3C06" modified="2023-09-13" version="1">MATLALKGVIYLGDRHFVTRFIDSNKKIWCNDGITTGEICEPTGSLGEISEKDLKKMENATAVMAIYTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3Z5</accession>
    <name>A0A9P6E3Z5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_872086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3Z5"/>
    <dbReference type="OrthoDB" id="3269685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="234"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="42931" checksum="14A9131B42916BDD" modified="2023-09-13" version="1">MSETPFYFCSPEGITLCRQILTQYLPFCPHDYQLEGTAMLLDEQDFIAISATGSGKTGYIYMSLLIVKALKKDPTLCPGAKFPDDPVTLVILPTTALEETQPDLKCLGEADEAGKHIWQEMLVTPGFESLVKSKKFQAQLLAIGIDKVHLLASWGKDFRPKFRQIAFIRSQFRRRVPLFGMTATLRKGLPMQLVLDLLGFHEGNFHLLRRSNACPDIQIIYRTLETSLGKSFPQLDWILEESGKVLIFCPTIHHGFRLAVYFWHIDPRGAVLKKNIHLFNSLNSASYNTETLKLLEGDSTSRITIATDKLSVGVDVSDFQLVVILDPKDLDDLWQKAGRVGRDQAKIKNAHTVIYFPSAKLSMQEWRTRVTGHSLGAPHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E448</accession>
    <name>A0A9P6E448_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_864900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157958">
        <property type="protein sequence ID" value="KAF9522145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E448"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF68">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="649" mass="71980" checksum="3A5799C85DC47BEA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4H2</accession>
    <name>A0A9P6E4H2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_864613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157950">
        <property type="protein sequence ID" value="KAF9522325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4H2"/>
    <dbReference type="OrthoDB" id="3223377at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="178"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="314" mass="34516" checksum="94FC3591208068F7" modified="2023-09-13" version="1">MEAPTNNLPLIPYNVVQTTGPLLLGHLLNWFLFGLLSLQIYIYYLSFPDDSLSSQALSYGVYLFELAQTIILTQAAFRVFAQGYGNLHILDEVGTNWLSAPIMGGIVAFVAQAFYARRIWILSKSIMVPLIILLLATISLAGAIALGVAAKLAASVGKFVGTESRVLSIVTGIWNGGSCLCDILIATSMTVYLTRRNSSIPRTRQLVKRIIRLTIETGTLTAVVALLNLILALLPNHPTYYRVVAGCLGKLYANSMMAVFNNRAHLWMDDRSGADSSIVFPSRYFNQDLEMDNLDGELQSKRTDTYIARGPVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E512</accession>
    <name>A0A9P6E512_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157941">
        <property type="protein sequence ID" value="KAF9522549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E512"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040180264" evidence="1">
        <location>
            <begin position="20"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="222" mass="25128" checksum="EF437C54E0BBA1D3" modified="2023-09-13" version="1">MSVLSYFLFLIFVLPLVLQMRSYLQSELLIPDLSHRDPSDMAVATFNPAPSSLQFYGLHGSPWLFFDAIYRSNNSPVQKSDTICAEQELKHGWSLVDENETISLPSSERERNQDPNSHHLPILYFRVRSSWASTPNSARHSAPCQKINSDQRTLLVPSLPTARVVRSPTPLSSNLAVPQLGFQRNRSLKYQRTDHIPRTDSSANTPHFSLFVPATARKVLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E548</accession>
    <name>A0A9P6E548_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="16">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_864007</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="16">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="16"/>
    <dbReference type="EMBL" id="MU157936">
        <property type="protein sequence ID" value="KAF9522719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E548"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000004">
        <property type="entry name" value="Acyl-CoA desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001522">
        <property type="entry name" value="FADS-1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00476">
        <property type="entry name" value="FATTY_ACID_DESATUR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="15 16" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 16" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="4 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="18">
        <location>
            <begin position="363"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9522719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="467" mass="53074" checksum="D6FFEDCD8256B1EB" modified="2023-09-13" version="1">MSRNIAKAAKAVKDETIPEDINIPDNYVQHTIKTQKALPPFQWSNWRNEFDWLNVVILCITPFAGFFGAYYTPLLWQTFLFSIFWYFVTGLGITAGYHRLWAHRAYNASLPLQYALALAGAGAVEGSIKWWSRGHRAHHRYTDTDLDPYNAHKGFWYSHMGWMILKPRRKPGVADVSDLSKSEVVKWQHKYYIQLILIMSFVIPTLIPKLLWNDAAGGFIYASVLRLCFVHHSTFCVNSLAHWLGETPFDDKHTPRDHFATALVTIGEGYHNFHHQFPMDYRNAIKWYQYDPTKWFIKAMQTIGLASHLKVFPENEVRKGQLTMELKKLKETQEKLAWPSNSDDLPVISWESFQEQALKRPLILISGFIHDVGSFIDEHPGGPHLLIKFIGKDATTAFFGGVYDHSNAAHNLLAMKRVGVLHGGMPQGVNDKSVPPSQRLKIARYNELSGSGYNSGTAASDGEGLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E572</accession>
    <name>A0A9P6E572_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_864210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E572"/>
    <dbReference type="OrthoDB" id="3202243at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="473"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="644" mass="73763" checksum="D6252252062880C7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E592</accession>
    <name>A0A9P6E592_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_878199</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0220 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E592"/>
    <dbReference type="OrthoDB" id="268928at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007919">
        <property type="entry name" value="UPF0220"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13180">
        <property type="entry name" value="SMALL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05255">
        <property type="entry name" value="UPF0220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9522779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="20521" checksum="EE7BF9F2E1DF49CB" modified="2023-09-13" version="1">MALPRSNYDPRRVCLNPFPEFTLGKHRRTFGVYLAGALFALANWTFLDAAVLSKHAKAPYGAPPGTDPPVHVTFTDWVPGLCSLLGYLVINLIDKDRIRGDEGFGDSRAVWRARLFLFIGFALMAGGLAGSVTILVLKYLVGESYPAQFTYYGYANVSQSVALMLSAIVLWIAQNTSSEYEYNLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5G9</accession>
    <name>A0A9P6E5G9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5G9"/>
    <dbReference type="OrthoDB" id="2563669at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040214730" evidence="1">
        <location>
            <begin position="25"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="311" mass="33125" checksum="10487F12CD4EB7C2" modified="2023-09-13" version="1">MTYYLTQMLSAALILSILIRLVSSQPNCTSESVLCSPRATCCPSGAFCNFNAAIPVCQYDQSPVRSGWRDSYAYPCENNPYLFSCDQPVNIQGFCCPIGSICLTVNSDPNKVVSCIDALGITTGALPASKAASFSPSLSVAQSTEPALLLSPEKAWNTTEATAGSCGSNTFHSTNVVNATISFNYTGPSILLNAMTSPQGGVFAVFIDGTQIKNSLDTFDAGQVKCIRRQYPPFSAPGPPGFGSRTSHSITIMHYGPSKLAPNGTVSSVVQLDSFVVPQFNRSVSGESRAVSGTYFFVFFAFQVFSMSMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E607</accession>
    <name>A0A9P6E607_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_65312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E607"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="2">
        <location>
            <begin position="3"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="629" mass="71797" checksum="0CBE68BA404F356C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E652</accession>
    <name>A0A9P6E652_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1264-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_821662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E652"/>
    <dbReference type="OrthoDB" id="1901244at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="26378" checksum="53B46B9C27F4BF9B" modified="2023-09-13" version="1">MSADQKSRSSEDSADITNNASGNPTSVKSQILSTAAGMLQEFEPVKNICAFLNAFHVYADEPSRAVESHHYCSHVNEDVRQCLIYDSNEKNARLIGVEYMITPQLYETLDQTERRLWHSHVFEVKSGMLIMPKPSMVPEAAWELAETKEMEDVIQLYGKVYHFWQVDRGDKLPLGQPKLMASITNESQVPGLWERVAERDRKLVADYQRKKAIRQGILEPQIHPDADQCRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6I4</accession>
    <name>A0A9P6E6I4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_799435</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DPH3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157920">
        <property type="protein sequence ID" value="KAF9523303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6I4"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="10">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="62"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9523303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="115" mass="13022" checksum="13E813757954632F" modified="2023-09-13" version="1">MGAYYDEIEIEDMAWDAEKKVYHYPCPCGDRFEISRRQLADCEDIATCPSCSLVIRVIFDPLDFEDEPEDDESSAEEQEGEDTSEDDESDEDHFEDALEKLTLADEAPKSVSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6K3</accession>
    <name>A0A9P6E6K3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation protein SH3-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_821521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157917">
        <property type="protein sequence ID" value="KAF9523454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6K3"/>
    <dbReference type="OrthoDB" id="10267824at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_uL2_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007180">
        <property type="entry name" value="PRK09612.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="4">
        <location>
            <begin position="95"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9523454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="254" mass="27588" checksum="8CA5A3BAEA43648E" modified="2023-09-13" version="1">MGRVIRTQRRSHPIFKSHTHHNKNPARLRNLDFAERNGYIRGIVKEIIHDAGRGAPLARVVFRDPYRYKLRKETFIATEGLHTGAFVYCGKKAALTVGNVIPVGQCPEGTIICNVEEKVGDRGALARTSGNYATIIGHQPDEGKTRIRLPSGAKKTVASGARASIGIVAGGGRIDKPLLKAGRAFHKFKAKRYSWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARRTGLLRGTVKVKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6U3</accession>
    <name>A0A9P6E6U3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_775294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6U3"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="543"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="577"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="669" mass="75933" checksum="79B5927273673B47" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8R1</accession>
    <name>A0A9P6E8R1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-I complex subunit VPS28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_871271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8R1"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="7">
        <location>
            <begin position="113"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="214" mass="24319" checksum="AFCB51E2A8EEA651" modified="2023-09-13" version="1">MSNPISLDEEVRLHSTNAEREKFNTLATLYGIIVALDYLERAYVRDSVTAMEYSPACTRLLSQYKTMLKLVGADVPSIEEFMKRYRMDHQAALHRINVGVPATVEHSSEAGPETGKRIAETTQSFITFMDGLRLKMRAKDQLHPMLQELVTGYARFKGSKEWEGRSRMVSWLITLNGMKASEELSEEQARQLIFDVEHAYAEFFRSLGGKEGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9B1</accession>
    <name>A0A9P6E9B1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS polyamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_885772</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9B1"/>
    <dbReference type="OrthoDB" id="5376138at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF134">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="112"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="586" mass="65325" checksum="58BE2F5B956C3828" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9T7</accession>
    <name>A0A9P6E9T7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_725005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157887">
        <property type="protein sequence ID" value="KAF9525186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9T7"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20710" checksum="F5E247EE06B30387" modified="2023-09-13" version="1" fragment="single">NIVLVDTPGFDDSYTSDSDILFMIADWLKSKYPEGTCLAGILYLHRITNNRIIGTPNRNTRLFEKLCGGSGEGGKKVVFVTTMWDKLRDQDFGLQKEKEFQDFLAPTVRRGAQVRRYDNTKENAQQIILDLAEQPSSALTTPLEDELVKQKQLLERTEAARALYTQYQTLLAHHKTTIADIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9Y3</accession>
    <name>A0A9P6E9Y3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_562762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9Y3"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28567" checksum="710F945482B8C095" modified="2023-09-13" version="1">MSSTSKKPYDAFARGQTGSSPLTTFIFCAERALDPIIQYQILANGLGSSILSKLGLELIPDGPPTQIGVPLVDNLGLSPYRLLLLAMAAGGALKQIIWAVHLNREPLYISSAIYGPIFNTVVNGTNDLLATTAFFSGGVAGRLPAVFLGVALYIFGIITETVSEFQRKAFKDNSKNDGKVYTGGLWSITRHINYTGYTSWRVGYSLAAGNWYFGVPALSFWSYGFVTNAIPILDAYCSKKYGAQWEDFKQKTPYRFIPGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA77</accession>
    <name>A0A9P6EA77_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_772386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA77"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="147" mass="15875" checksum="1E7689F610961D11" modified="2023-09-13" version="1" fragment="single">LTAKDLTIYSQDTEFGSPLIAAVEKGSMELVQLLLSRGANLNIKAEKTDYPTALQMAVRNGSVEIVKLLLVKGADPNVNGGCYHTALQIAALNGSIEIVGLLLNNTIRAKPNTKGINVLDWTEVLLTLLKVVKAQLYMPPYSKVTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB02</accession>
    <name>A0A9P6EB02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB02"/>
    <dbReference type="OrthoDB" id="425354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="52" mass="5890" checksum="4A288003A69F2E16" modified="2023-09-13" version="1">MAHGKSSNWTANQTWGIEDYQGEGRYIRHVSFTGPKSEVINTKTVYDYIGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBC7</accession>
    <name>A0A9P6EBC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LIM-domain binding protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_884996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBC7"/>
    <dbReference type="OrthoDB" id="774557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029005">
        <property type="entry name" value="LIM-bd/SEUSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10378">
        <property type="entry name" value="LIM DOMAIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01803">
        <property type="entry name" value="LIM_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="798"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="940"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="950"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1041" mass="110414" checksum="8D9A1451F4D3C6C4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECC2</accession>
    <name>A0A9P6ECC2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AhpC/TSA antioxidant enzyme-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_770409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECC2"/>
    <dbReference type="OrthoDB" id="40334at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02970">
        <property type="entry name" value="PRX_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF3">
        <property type="entry name" value="PEROXIREDOXIN-LIKE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="204" mass="22537" checksum="A1130B378358014A" modified="2023-09-13" version="1" fragment="single">MPTSPSKQHWHASSGPEYALPTVAQITHAASLPLYGEEGRQVRFGSLFEARKTIVVFIRHFWCPLCQDYMTVVSEVVKPDMLERGHERVDFIIISNGAHGMITKYRQMFKLPFKIYTDPTLALYKALGMGKDGSKGYVKHGLMSGIAMVVVRAIKVGMPVWEKGGDVGQLGGEFVFGPGLTCSFAHRMQTTKGHAPIQEVLQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECS6</accession>
    <name>A0A9P6ECS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_895957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECS6"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="81"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="613" mass="69529" checksum="4AD91E2AA787011B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED35</accession>
    <name>A0A9P6ED35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED35"/>
    <dbReference type="OrthoDB" id="422106at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="51501" checksum="CB01DF0EE877ED78" modified="2023-09-13" version="1">MDIVEIAPSAELGTLSYDEEAPYEAQLPTEAELAAEQARSTSLANRIGASKVYLLEDSSAAPNRLTKRRQENGEDVVKMEEDDDTEDSDPNYRSNAILFSGEPISNLRTARLFAYATHFDAHPMGLEWVDDKTCVFVFSSKKDAKEAFSKLTKPTPASTSNALTSTEDVAPMALDDPVDVDFISAKPFPVALWPPEERINSTLGKGQGLKGPIRMRWAKVDDIKQKGARDASQFYKKHGKSAGKELFNGRELPPASEPIPGKRKREFDEEEENERRRQELDRELDDFLREDDDEESEEGERNRKRTRRLQKSASPLYEADARPTRPASPPSKMRSDYISRDGRTLLERTSVLRRHAAASDPLDEAPGLASRLTAPLPRRAVGRRRGGRDDDGRNRVGDHIRSSDYEGSGSDREMTRRRGGRKEDDRRSRGGGGGRPVERPKKTQQELDDELDAFLNAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED43</accession>
    <name>A0A9P6ED43_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_937440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED43"/>
    <dbReference type="OrthoDB" id="3355826at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="47"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="279" mass="30572" checksum="C913B4FD8C7F22E8" modified="2023-09-13" version="1">MDPFTPKQCPPRTPNVLDFTQGSFSKDIAREALSLVPPMTNTSVVHDNACGTGAVTEAIVASSQKPGKLFATDLIPPFVASVEAKAHRNGWGFVKTATMDAMNLLGFESNFFTHSITNFCLQGLSDPSKGAKEIYRTVKPAAEGGVAIITTWATIVQGSAIQTASEATRGKGVALRIPWIKQKTTTEWLERHLKNAGFTSVEVIQQVGYTETEDLEKWCELMWAFLGIPSDGWTQKDETQWENAVKLIFELVQSNEDVELHEDGGARIRMLANIAIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDT8</accession>
    <name>A0A9P6EDT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_934317</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDT8"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="57"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="496" mass="56072" checksum="AF8F27D7BDBBEA6E" modified="2023-09-13" version="1">MFTGGTYNHNVTTNTSPQDQGIQDLSKIASRGAMHDSSARVPHPKCHPESRRRIVEAFIAWIKNPNPPEPEHVRWLNAPFGHGKSAVMQTIVDTLLSTGFAHLVAGAFFFGPGHVDAHDLLPTIAYQIAINIPGMRELINEAVMRDPTIPSKSMELQLCHLIVEPLLALADGLHHIHHPTILIDGLDECATTAAQRSVLDIVADALVKHKLPLRFIVASRPESHIQLKFQVQPLSQLSKFIELENDLQAKLDMGAFLVDSFDAIYEGHLEVMSEVPKPWPSAQEITELIIRANGQYVYLTTVVTFVDAEFFDPVSQLDVVLKGRPDYSEVSNIDFLYRQILQRVPKAHRTVLQHILASLVIARHNSAAFREERVELPKLVELLTVHVIADIWDHTKQQILLVSQALQGVTKLNRAWTSEEIPNQCPPDFIETFNPPYLQPRHHSFLEFLEDENRAGEFYCNRKLAEAEWISRSQSLLKDALRYKYVPRVAFIKLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDV3</accession>
    <name>A0A9P6EDV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_432480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDV3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="18002" checksum="EE407001F754618D" modified="2023-09-13" version="1">MSQKTSPEIGSILLFNENFEQQLQRVQKDVGREWPKFRDSNQAFKIVKKELEDLNLEDLGEFLSVYSILLDCVHQYPHKKDIAHRHSLKQALQTDAYDIIRCIWQDALQNLEPFSRRKAGDGMFLDISTFYLALFRLADDSYGDEEFAQLWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE92</accession>
    <name>A0A9P6EE92_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ERCC4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_855339</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE92"/>
    <dbReference type="OrthoDB" id="361020at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20078">
        <property type="entry name" value="XPF_nuclease_XPF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000002">
        <property type="entry name" value="DNA repair endonuclease XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047520">
        <property type="entry name" value="XPF_nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150:SF0">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="11">
        <location>
            <begin position="794"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="551"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1039" mass="116030" checksum="84F46D180531C0A2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE99</accession>
    <name>A0A9P6EE99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_895353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE99"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040228737" evidence="1">
        <location>
            <begin position="20"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="34"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="471" mass="51244" checksum="9BAAE99739EE4312" modified="2023-09-13" version="1">MAKLSRFLLPFVFLTTTTASLQSVASRATTDTTTVKAAWYTAWHTSFLPLDKVSWSKYTHLIYAFAVTTPDVTTLGLQDTDTKLLPQFVVAAKEHNVIPMLSVGGAGGSKYFSPLIKTSQNRTAFVKTLTDVVQKYNLSGLDIDWEFPGERGTNCIIFDANDTSNYLEFLRELRATPIGQNLVISAAVWHFPWTDSTGNPSKSVAPFADVLDFVEIMNYDVKSNPAIGASPSSPLDDSCAPQGAYNRSAKAAVKAWSNAGMPLNKLVLGVPSYGHSFTVPISASGTGPVTSTGLDQYPFYSIGTKARGDSWDTTPYTDDCGLPQGPDGIFQYRGLFEQGYLKDDGTPHDGVNYYFDECSQTPWLFNTSSRLLVTYDDPRSYDSKGGYIHSAGLRGFAMWEPAGDLNDVLLDSIIHATQYGGNGSTSDTSGGATSAASHNGYESSFDIKQQLQRKLLTTLCVVVCSLLWYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEQ5</accession>
    <name>A0A9P6EEQ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEQ5"/>
    <dbReference type="OrthoDB" id="2940323at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="353" mass="39349" checksum="E10B9CB658094214" modified="2023-09-13" version="1">MRQLQHPLLCTTPKLFLVVLAVFFNLWLLLTTYHQWHSPVVDRGGFKSDPLDGLTQPHQRQVVMRTTPTNRAGIGSVIGQLRSSAAIATMLGASFATTGRQSEHHYQVASLLNLDMLENQFETAGKICSLMSLPNPSLISEGMETWCNDPQLADSKQAAHIQDVRSSLEKCTIILDDRPWDVRQDLSRCTWEWVKQVFSKLGGERRQRGGIGIHIRWGDMANGQSYDHKTPHRSIPIEVGARILSKIRGCGVQDELSVYMEAHNSTILDGLAEFQPYRLVDTGDDINDLLDLAANRVMILDVGSYTAVAHQIAEGGISVVPEVERFEATGYNSVLLWDELLDLTCDSILSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEX5</accession>
    <name>A0A9P6EEX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="2 7">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_855606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-formylglutathione + H2O = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="2 7"/>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEX5"/>
    <dbReference type="OrthoDB" id="420518at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000002">
        <property type="entry name" value="S-formylglutathione hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="292" mass="32054" checksum="4F89DF48C0335A16" modified="2023-09-13" version="1">MTNIPALEKISSNKVFEGHLEKYKFKSNALGGLDTQFNIFIPRASNGSKVPVLIYLAGLTCTEDNGAQKGGFFTPAASQGIAILFPDTSPRGAGIEGENDDWDFGTGAGFYLDATNPKYSKHYNMATYITEELPKVVEAAGLPIDFSRQSIFGHSMGGHGALTLYLASKTKQYRSASAFAPISNPSKCPWGEKAFKGYLSGGVEEALAKYDATELIAKATDPLHILIDYGTSDDFYKKGQLLPENFLKTARDAGYDEVQVRVRRHEGYDHSYYFISTFASDHIHFHANFLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEY0</accession>
    <name>A0A9P6EEY0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_767046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEY0"/>
    <dbReference type="OrthoDB" id="3360976at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046528">
        <property type="entry name" value="DUF6593"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20236">
        <property type="entry name" value="DUF6593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6593" evidence="1">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="186" mass="21292" checksum="C4AFBD7379E6B16A" modified="2023-09-13" version="1">MHLYLSSHNPWKTNYCNEDGQIIYKAERGGPTFGARRIMISKIAPSKFNPQATSIDEFALRDEFEHLGEVEYHLIKNSRIKYGGQDQSISKFFRKSGWAFFGRNRIFTGPDGIEYCWKLTSRVSKTPVAVFHRKRVGFIRGARPGSLEIMSEGENMIDIILVTFLYIEKLRKDKERASRSHGGGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFP0</accession>
    <name>A0A9P6EFP0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription termination and cleavage factor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_883736</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFP0"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription termination and cleavage factor C-terminal" evidence="3">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9528149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="215" mass="22880" checksum="B879BBA930F3D882" modified="2023-09-13" version="1">MANPTVANEQLLELLLTLKKTTPQAAKGILNAQPAIAYALIALMVSMNAVNIEVFQKTLAEYGAAAAPPDPVPPQTVAPTPMPALPPHLQTQYRTGGSLPPTMPAIQPPMHTPTPPYGYGAHPPPTLPLNGHGHGHHTPPVQNNYGAAQGYGYGHHAAPPVQQQPALPEALANIPPEQKALIMRVLSMTPDQINILPPNERATYIQIAYQLENMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFX5</accession>
    <name>A0A9P6EFX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_854486</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFX5"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="63"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="55108" checksum="3337912AD0157D01" modified="2023-09-13" version="1">MSMNEVVSKLWIGDLKSAMNVRQLKENGIFSVFSAMRGRITIHETFVRHQIQLDDSEDEDILIHFLPAIHFIQAELDKGRGVLVHCQAGISRSATIVAAYLMYSRNLDRDSALKMIRQVRPFADPNANFYEQLELFHKAQYKISRKDKDIRMFYMGRAVEEIMNGDGTQLETDMFARLPQESPSSTPGPVPRRRIRCKMCRQELALREHMLDHGQLGPATPPLASPAISRRPSSSVQPATATPLPGGSIVHVPGRAEPKRRPSGLSSVAAFGDSLSMSSIRDDSKKKSDSALDTDEEPDSPRKSSNATQTLQLNGEGATEEDIAAKASRVLGRRLSGFVRAGTSESGPANKKTDDSFFIAEGDAVATHSPKSAAEDKVDHAVTHLKSPSDLASQLFANPKLAALRSQPPTPGAQTSPTFPRHQSGLISSAPILANPLCSGYFVEPMKWMEHFLSAGQLAGKVSCPNKKCGAKLGNYDWAGVRCGCNEWVTPGFCINRSKVDEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFY0</accession>
    <name>A0A9P6EFY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFY0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="90" mass="10784" checksum="E63E428BAE468B7D" modified="2023-09-13" version="1">MLSIYYCTIEAGRFGIRQSVRDSCSNSHCCYSWEREDSRWDSYNESFEWEEIDRKLPLEETQGKTWEDSPLPWPWPIGLDMIRLDVGRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG51</accession>
    <name>A0A9P6EG51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_869279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF10">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="729"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="766"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="948"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1215"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1271"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1331"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="592"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="1483"/>
            <end position="1521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1542" mass="169463" checksum="A88C19E2113B06A8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGB5</accession>
    <name>A0A9P6EGB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_906888</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="436262at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="72"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1110"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="484"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="896"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="996"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1337"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="513"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="915"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="996"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1016"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1337"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1352"/>
            <end position="1367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9528388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1381" mass="155767" checksum="87B993B7686214AD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGL6</accession>
    <name>A0A9P6EGL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGL6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040127342" evidence="2">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="14221" checksum="8B886CC4CD963329" modified="2023-09-13" version="1">MLFVLRFMIAFLFALTAVRALQYHLSSLTTNTPTFTTHHDRMASINAPATATTRPSAVGTSVLTHYSTTTAIARSTAIMTNTQTLWRPAPDSSGTSDPSAGPPSSPVSGALRISVGQLEAFLIAVALSSIIPIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGR9</accession>
    <name>A0A9P6EGR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGR9"/>
    <dbReference type="OrthoDB" id="2880459at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="486" mass="53794" checksum="037255A1DA1A5302" modified="2023-09-13" version="1">MQVHNPLTRRINLTLPGLPDLPSPSSRGYASSSLPPSPTTTTTTTSSTSISRIKAYNFDIDRKGKPLAVLTLYANGDHSPSTPTFVEGQPIKGQLKLDLEKAENFLNINIRVQGKLSMVTGPTESDQVIFLDIVHPLWSQSVGDPRHTATSFTSWSPDPFRAMMDPFNGKLPEGVYVWHFTIELPKYVVVPVGSDRPQTFKLPPSFVEKNVGATIVYDVTAKLTTNSLLRTTHRTTAKYDFIPSTRPPPFLPMRAAAYRDGVPLPPPSIDEEGWHASKPAQFTGLLFKNKVVYLDCIATSLLVLKLVYARGTVIPLFLEISGQDTQAVALLSSPLAVFCRLRRTIKFHNNGKRLGDKQQWKDGFSHSQVATWRKVEDRQRTSDNSKKRACLQGELLLSNTLKPTSALAYFEIKYSVVLLPFAITGFDAEGKTELIKEPVEIVTGTGYAPGRRSTRMSTPSSLASSDISSPIPEVPVRREVRDRGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH20</accession>
    <name>A0A9P6EH20_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_835425</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH20"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="6">
        <location>
            <begin position="10"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="7">
        <location>
            <begin position="67"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="21419" checksum="031A986FA7927D47" modified="2023-09-13" version="1">MAEQKTTPTNVMKEPRIEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELRRQNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGGRVAKRKQQKARIGFQHRIKKEDTMAWFKQRFDGIILVRTLIFGLLFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH51</accession>
    <name>A0A9P6EH51_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">cystathionine gamma-synthase</fullName>
            <ecNumber evidence="7">2.5.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">O-succinylhomoserine (thiol)-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_791255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-succinyl-L-homoserine + L-cysteine = L,L-cystathionine + succinate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20397"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="EC" id="2.5.1.48"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-cystathionine from O-succinyl-L-homoserine: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="7"/>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH51"/>
    <dbReference type="OrthoDB" id="10047078at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000094">
        <property type="entry name" value="Probable cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000063">
        <property type="entry name" value="Probable cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051750">
        <property type="entry name" value="Trans-sulfuration_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42699:SF1">
        <property type="entry name" value="CYSTATHIONINE GAMMA-SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00058439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00066530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00083849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="632" mass="69282" checksum="D99281CE10DCD591" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH87</accession>
    <name>A0A9P6EH87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Acetyl-CoA acetyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_852398</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH87"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="13">
        <location>
            <begin position="22"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="14">
        <location>
            <begin position="286"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="11">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9529601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="42735" checksum="C6432749CC75D98D" modified="2023-09-13" version="1">MDTQSSSFSGKAAILQKREDDIVIVSAVRSAITKGRKGGFKDTKPEQILSHVLRAAYEKIKLDPKLIEDVSVGNVLPPGGGAGAARMAALHAGIPVSAAVNTVNRQCSSGLTAISQIANEIRAGQIEIGIGAGVESMTHGYGAGALAEFSEEVTSNKDADDCQLPMGITSENVAKDYNISRKVQDEFAAKSFQKAAAANKAGKFKDEIVPIKVKIIDPKTEKEHEIVVDQDDGIRDGVTAESLSKLKPAFAKDGFTHAGNASQVSDGAAAVILTRRSTAKRLGLPIVGKYVNSAVVGVPPRIMGVGPAYAIPRVLKIVGLPQNDVDFFEINEAFASQAVFSIDHLKIPYEKVNINGGAIAMGHPLGCTGARQVATGLNIAKQTGGRVFVTSMCIGSGMGMAAVFVSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHR8</accession>
    <name>A0A9P6EHR8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_853042</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHR8"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF41">
        <property type="entry name" value="CHITIN SYNTHASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="823"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="853"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="876"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="13">
        <location>
            <begin position="245"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1043"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9529297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1129" mass="123647" checksum="F8E333D3C766B18A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJC7</accession>
    <name>A0A9P6EJC7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJC7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16730" checksum="AD9A9736C1BBC06D" modified="2023-09-13" version="1">MSNVECRLVQCILRLGGLKLISSTRTNHSALFPSSLNWPSELIRTFHDRQSTASTKLGLGLGVQSTSGISRLSTDGTDIHDRHALSETPSPPFQPWAIAVLPVVCSLIRLPVRLRTCWSMHDLQYLERYFPFISASYSVLRAQKSIMSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJX8</accession>
    <name>A0A9P6EJX8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_810873</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423221at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF26">
        <property type="entry name" value="FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1821"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1324"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1266"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1339"/>
            <end position="1358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9530466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1973" mass="221021" checksum="13C49319D4C6E7E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK33</accession>
    <name>A0A9P6EK33_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase metallopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_882060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="3">
        <location>
            <begin position="145"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="845"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1188"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1489"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="845"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="861"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1190"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1215"/>
            <end position="1226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1552" mass="172567" checksum="D113F1BCA702A14C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKJ7</accession>
    <name>A0A9P6EKJ7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_850321</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKJ7"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF241">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="33"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="240" mass="27379" checksum="0C9B78EF47D38DD1" modified="2023-09-13" version="1">MVYPSETSEEPRTADAPVLDWASTDLANDYAGHYVKIIDGVFSPEDCAELIKLAESDSKWKQAAVHYGMGADQNYVNTDYRNSERILRFDNDAAEKLYKKLLPYVHELVEVKAGSKWEGIFGQRGPVKGTWNLVGLNERLSFLKYRKGHYFRSHCDGQLDLPDGRKSRVTLQIYLGEDGVQGGATRIEGRKGKHLDVLPKKGRVLIFQQRNIWHNGQDVEKGIKYAVRSDFMFRHTPESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKW8</accession>
    <name>A0A9P6EKW8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_904320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKW8"/>
    <dbReference type="OrthoDB" id="2904962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="453" mass="52086" checksum="C24E9BCF8322614F" modified="2023-09-13" version="1">MLKKLFGHFGSHSHKPPELCAQVELEFDSLANPPFRHLKIFNDLQNIALLHSTLNQPSFSEANWQLPLPYDVVFAIIHIFLNDSKTLWNLYGSCASLHQLCGPLVHQTISIHTRSRAAPSTLEKFARSIAQNPQVIANLQTLRIIDDGKMFQGCRPITAEEVSLCFILTRNYPLLRRIELDLQVVWDIIPPPLQHAFHIAFALPTLREISTLEMCAEVSGPPQFVEFRQIQCSPEHLTVEDQRLDGISTFTNMFNELTSPLRLASLRILECRSYPQFIHLLNEPLERCSQTLISLTILIIGKCSSSYLVKLEPLTTLKMLTLSCDTKLTSLNNNPISLANFNFLVATISSSQKPSSIEDIYLLIRTHRFDFARRLPWNHLDDVFKRNKYHSEWPNLRKIWVKLIDEDLTQRDEGWYKQGRIEIDILPLLPNLASLELVQFEMVFGKHQFLSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKZ8</accession>
    <name>A0A9P6EKZ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tropomyosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_848607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKZ8"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000001">
        <property type="entry name" value="Tropomyosin alpha-1 chain isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="19044" checksum="381497B78B74C106" modified="2023-09-13" version="1">MTDRIREKMTQLRGEADAAIARAEDAEKKVKLLEQELLSKEQENRSLTHRLGLLEAENEKAEAKIQDYKTNSSDYDSNKTNADNLSRKVQLLEEELDSAEKNLKETVEKLRQVDVKAEHFERQVTRAEQERDAWEKKHEEVNERYKKAQQDLEELEKSMNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELE1</accession>
    <name>A0A9P6ELE1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELE1"/>
    <dbReference type="OrthoDB" id="152248at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040306112" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="23549" checksum="A2C4713BE432867B" modified="2023-09-13" version="1">MFNFFSSAATLLTYILAVGAAPPRDGNNLPPVIIPTVPPPPGFTITSLGVLGTGCPSGSAYYVLSTDKTAVTVTFSQYFAEAGPGIPISHNRKNCALTFGINVPPGFTYGIASVDYRGYYFLDKKVIANQSAIYYFQGQTLQASARSNITGPIDGEDYTWRDNFDLVSTVNSPCGVPSVLNINSDLRVSNSQNPSGVGYIATDSVDTTLNTTLNFQWQKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELK5</accession>
    <name>A0A9P6ELK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_850409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELK5"/>
    <dbReference type="OrthoDB" id="3064298at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040119369" evidence="3">
        <location>
            <begin position="25"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="223" mass="24073" checksum="73DD102A27A4019A" modified="2023-09-13" version="1">MLKHFTAGGLLGLWALSSLPTAAAVLSWSKCTKNEQGVETCQDSVPRGARIAIAVCCLIVLMALLSLVIFICVKRRKAKTQEKEYDVEASQVDGPPAIIATEYDPHSGGPSHIYGSGPKTTDSRPPSPPQMTGPSLPVAAYPTPYDSRFPDQSRTAPHSQTTFSEQPYPFAYSPHNGNFNPPKTAFVSNGFPRPILAGGRLKDKLKERPSSISSLTLQPPNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN89</accession>
    <name>A0A9P6EN89_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_832893</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN89"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000595">
        <property type="entry name" value="Protein kinase, putative (AFU_orthologue AFUA_5G11840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="187"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="101"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="414"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="699"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="874" mass="94081" checksum="281D9B54FE2D9433" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENK5</accession>
    <name>A0A9P6ENK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_847581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENK5"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000064">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="30"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45293" checksum="8526AB7A7C3840F5" modified="2023-09-13" version="1">MSAEIWQEVPLAPPDSIFKLTAAYKEDKFKDKVNLGVGAYRDDNSKPWVLPVVKKATSILLNDETLDHEYLPITGLAEYTSAAAKLILGADSPAVKAGRVSSVQTISGTGANHLGALFLSRFYQFNGKKQVFLSNPTWINHYAILRNVGIEPVEYPYYDPKTIGLDFEGFINSLKSAPERSVFLIHACAHNPTGVDPTQEQWKAIAEVIKEKKHYSFFDSAYQGFASGDLDKDAWAVRYFVEQGLPLLVCQSFAKNAGLYGERVGALHIVPPDAETANRVKSQLSVLQRSEISNPPAHGARLVSLILNDAGLFEEWKRDIRTMAGRIIDMRNELHRQLTEVLHTPGSWDHILQQIGMFSFTGLNPAQSQKLIDEAHIYLTQNGRISMAGLNSHNVEYVARSIDGVVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENL8</accession>
    <name>A0A9P6ENL8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENL8"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="455" mass="50130" checksum="25C96054D203631F" modified="2023-09-13" version="1">MAQVLNIHTPSSSFAIIHSLTQENLFDLYNKLSRKHNTDYYGEQVGPEWLKYEYNDSVWNLDDDSDYTIFGWRQQELKQLEEQSQRSDDETQPIASSSKTPLPSRSSGTHQPASTGLKSTPTLHLHNPKKPLPIPPEYCNPSYYVFHARAKVHSNARASSRAGSYRTNGHHSPATSSQASTTGKRGKKGKGGVVVGLEDDSEGDNTVPRFQKQFNRFHAENGVRTVMGSIGPVQNVRMLLKAGYRHVYISRKFAVKHEFIPADAAPGNYGYGGLVNIGSWPITLVPSASQPNKPATRYLKPDAFTTANHNHDNQHHRNGSTSTSPTPSSGLHRREQSTSPIPPSILSSTQGPKSTTNGSARRTKRTSIPTAGNSHQNGNSSTTSQQQQTISVSVPVYLSEEPHFDVVLGRSFFEKRQVKLSTVDPTDVVCLDTGEKIECELVVLKDGRGEIVTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENQ2</accession>
    <name>A0A9P6ENQ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_847715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENQ2"/>
    <dbReference type="OrthoDB" id="2524788at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="172" mass="18082" checksum="DC069A7DE9A95D09" modified="2023-09-13" version="1">MQMSSTHAADTEYLVRQAANSGYQWSSLLAPPAYMAYVVARRGRTSLSLNKVLRATWVGGLGGSVAAGSVAYARYAYSGEDTVRVRRIKAAYNTDALRRNDHATIGGVVVGALTPAILWKRGAALNLILGGFGIGNAFGLLTHYGRAVSGDPAPKIDIALPGAHPEVETPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENV1</accession>
    <name>A0A9P6ENV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_848162</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENV1"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="11"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="302"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="383"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="222"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="499" mass="53748" checksum="B0B4D60EDD5875C8" modified="2023-09-13" version="1">MALSRSARISILLVIDIIFFFVELIVGYAVGSLALVADSFHMLNDVMSLIVALYAIKLTNNASDSRYSYGWHRAEILAALINGVFLLALCFSVSLEAIERFFETPSISNPKLVVIVGSLGLASNFVGLFLFHEHGHSHSHSHSHSHPSSSRASSIRNGSVSHSVSGNTTPTQKQSSSAMPIRKHSHSASRGRSPIRSGQHVPSESFSSLYGHPAATRASLVQTAQDMASARSPSPPGLRRDSMGLPRRSIDSNAGATSDVTGPDFPRASSPLPDQSEQTPLLRHDHSDHVAAGHNHGHGSGHGHGGHDHSSMNMRALVLHVLGDALGNVGVIATGLIIWQTAWPYKYYCDPVISLVITIIIFSSALPLVRSASFILLQGVPTTISLDDVKDSILNVDGVLSLHELHVWQLSENKVIASVHVLASRNHDFMPIAAKIREVLHYHGIHSCTIQPEYYAPNNLISDEHLKTTADSSCLILCPADEVCNPSENACCPPPVVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENV3</accession>
    <name>A0A9P6ENV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_670336</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Interacts with G-actin; ADP-actin form.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENV3"/>
    <dbReference type="OrthoDB" id="10006997at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028458">
        <property type="entry name" value="Twinfilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759:SF1">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ADF-H" evidence="9">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="ADF-H" evidence="9">
        <location>
            <begin position="97"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="268" mass="29334" checksum="4C652E87F261120B" modified="2023-09-13" version="1">MILYYVPDGAQVRDKMLYASTRLPLLKALGSSQFTDSIFATSKADLTAESYEAHLRHVAAPNPLSSREKELADLKAAENAAASYEGSSVRHGHYGGGPGFTWSSEAEDAIKDLGAKTEDYIVILIQTVDPQSETLLLHSFKQINVSTIGQEIPTSQPSYTFLSWEYTYGLNPGRDIIFIYSCPSDSPVKHRMVYASGALSTLLAIKDLLGSLPSSPRISARRIETSEPTEVNEAFLKLELGLPDKEAVSDTPTRPQGFAKPKGPPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPR7</accession>
    <name>A0A9P6EPR7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_633137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPR7"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040543970" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="48"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="555" mass="59579" checksum="06CFC86592D4A8A4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPW2</accession>
    <name>A0A9P6EPW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_844591</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPW2"/>
    <dbReference type="OrthoDB" id="6354873at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="194"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9533831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="345" mass="39738" checksum="43439CA4E23EF45A" modified="2023-09-13" version="1">MDLVLSLFDEYVLDTVYARLVPLSAFASSVNSAPGLSSKLFLAATDASSSPWTRLVSRLPHPELKHEYLAPLFNATMGSGSATSAHAFSDISAWPRDYIPRQLISLTAITMVGIHVLYFLFAWISYTFIFNHDMMRHPKFLKNQVKLEIQTSVKSFPGMMLLTLPFFFAEVRGYSMVYSSVDDYGWAYLIASVPLYLLFTDYGIYWIHRWLHLPIFYKYIHKPHHKWLVPTPFASHAFHPLDGFAQSIPYHVFVFVFPLHRVLFIGLFVAVNFWTIFIHDSDMVTGHVLEKFINGPAHHTLHHLYFTVNYGQYFTWADRWGGSYRQPEASLDPLLEVQALDKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ51</accession>
    <name>A0A9P6EQ51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_585373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ51"/>
    <dbReference type="OrthoDB" id="1602884at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052818">
        <property type="entry name" value="NEDD1_Spindle_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414:SF1">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="472" mass="50251" checksum="D758397491B528CB" modified="2023-09-13" version="1">MFAATTADTLSVADYALLKKAPSSIPSCLDLIEPPTSTSWAPDNSSLFIATESTVQRYDPTTNILRDVYTYNGAGGIQSLAPKDKNTAIFAAENDVHVLDCSGSDTKITQTFASHTSPITSLSLSNDVTLLASSSFGQVHVHNLTLGSHTVLRGLPPTKMDSVVFHPHSRTRLLVASERQIFIYDTTRPSNPLKIITLTEATTGDIISVACSPFSKTLVATATSEGFVALLDLEKEKSLVRTVNMKVTLSTIDFTTEGGAMYLGTNTGKVLILDLRLLDKPPKSIVISQHGNPVKTISVQKKAKSSTDGNSKAFITNATTKSSVEPLPSGRRATSSASTQSLKAASRVAPSPARARAGKLPSTTTPIQRRGPSALKEAAPASSPTAGKTAAALRPKKVLSPSRDPLGNSLSGQSLRYVVHSGIDLIPLKARSTNSLKSSEEINQLPHQSKLRNLLPKKPYPLGPRQLLKLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQD0</accession>
    <name>A0A9P6EQD0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase phi-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_845272</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYBBP1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQD0"/>
    <dbReference type="OrthoDB" id="342531at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000182">
        <property type="term" value="F:rDNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007015">
        <property type="entry name" value="DNA_pol_V/MYBBP1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213:SF2">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04931">
        <property type="entry name" value="DNA_pol_phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="743"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1141"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="779"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1162"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1178"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1188" mass="132588" checksum="B5F08129B8700EFB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERC8</accession>
    <name>A0A9P6ERC8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_831965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERC8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="17127" checksum="20215AC3AF2E58C9" modified="2023-09-13" version="1">MAITVEVSVAIYVLFYILRSRQKLISRDPHRLRSTTYSKRPTLMHYPSDSTLNPSTRSRSSSINNSRIPRGYVARMGHKIRPRSFSPIRVSPSRPVIFGERGEEEHSIKVTLMVTPPTPAKKLAKYLNDEDESELDSLGSVRQQASERASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERE2</accession>
    <name>A0A9P6ERE2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_481073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERE2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="11631" checksum="8A67B09EF073C038" modified="2023-09-13" version="1">MRICMSRSRLWKSIAFCGRRWTTVNWTPAGFSGKEWPGASATLASGSASDLAQAQFYSSRKRRNYFKMKPGYFLLMGLYLKIRPDCSRIMLVGKKVVLVPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESV7</accession>
    <name>A0A9P6ESV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA synthetases class II-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_844188</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESV7"/>
    <dbReference type="OrthoDB" id="439710at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04317">
        <property type="entry name" value="EcAspRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="entry name" value="GAD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047089">
        <property type="entry name" value="Asp-tRNA-ligase_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="178"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="675" mass="75729" checksum="EE93472D235F20E2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET06</accession>
    <name>A0A9P6ET06_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_844178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET06"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="666"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="666"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="767"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="792"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="820"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="846"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="973" mass="106532" checksum="444730A7FF04352F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET33</accession>
    <name>A0A9P6ET33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_901623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET33"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="898"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="922" mass="104104" checksum="B40825108E4B1A74" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETY4</accession>
    <name>A0A9P6ETY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_879095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETY4"/>
    <dbReference type="OrthoDB" id="3044497at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="230" mass="27377" checksum="9C126B1D0CC394B5" modified="2023-09-13" version="1">MVKWRGQLLALPVHDLAQQLFRPIFTTAWPPRKLASNPSEPMMKILPQVYNQLPLHQLLKPHEKRPPGKAENDREGYRRKPERHGDMTLLGDRYLKIWRIIDPTGMPSRAFRKLTKALSRSQTSILARVRTRHVPLQAYLHRIHKEDSPIYQLCQREAESMEHYLKRCLSFQWARRKLRRRLGGFREVDVDLLGKPEHIRDLLRYIAETRRFEDSHANLKEIPHRRGRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUG8</accession>
    <name>A0A9P6EUG8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_754685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUG8"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF3">
        <property type="entry name" value="AMINO-ACID PERMEASE PB1C11.02-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="59"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="571" mass="63132" checksum="3625696A09476D6C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUH9</accession>
    <name>A0A9P6EUH9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_802067</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 12">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUH9"/>
    <dbReference type="OrthoDB" id="1715808at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000001">
        <property type="entry name" value="Electron transfer flavoprotein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 11 12" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="13">
        <location>
            <begin position="28"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="282"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="299"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000089-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9535596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="352" mass="36258" checksum="9F05CDF6B7678399" modified="2023-09-13" version="1">MLRTSSLLCRRALASNRNYATAAGSTHALVLLEHTEGVISSGSLSALTAAQKLGGQVSAIVVGSEKHVPKAVETAKSLNGVNSVLYSASSQYAHSIPENLTPLFQNLLSSSSNTFTHVVSSTSSTSKSLLPRISALLDAPTISDVTSVSHDGGSNTTTFTRPIYAGNAISTVTASGDKVPIKFFTVRGTAFAPAAEGSGTAEAKSIDAVDVPNPTTEHIKTTIAKSDRPDLGVASRVVSGGRALKNSETFEKTIYPLADALGAAVGASRAAVDAGYVDNSLQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKLIVAINKDPDAPIFQVADAGLVADLYDVVPELVEKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUN7</accession>
    <name>A0A9P6EUN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUN7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="28591" checksum="F7728128B58B89F5" modified="2023-09-13" version="1">MEILTTALVCIIVIVTITTILLRQFFDGACYLDFIGNETCACYDAEGTPFGSLEVDGGAQRSNAGLESARAADIEVLKASITTLNKAIEVLKLEMQARELRSTNNLNYSFRHCNLIETDINTIAAPVYNYGTWHAPSDSLSPHHVGDQPKTLMASSTLQVPDLAMDVTAAHTTDSEVMHKASVDPQALSLVQEELASLQVSHINTPSHINDSSTAIPATHATLSLCHTPIFFLSLSELAQMISQHLGGGSSSDSFRIHQDLANHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV89</accession>
    <name>A0A9P6EV89_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Galactan 1,3-beta-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_842255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV89"/>
    <dbReference type="OrthoDB" id="9970295at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04081">
        <property type="entry name" value="CBM35_galactosidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18821">
        <property type="entry name" value="GH43_Pc3Gal43A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CBM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040266757" evidence="5">
        <location>
            <begin position="19"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="6">
        <location>
            <begin position="322"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="446" mass="47463" checksum="F34AB541A134ED81" modified="2023-09-13" version="1">MKVQSLLTLFTFAVVSQAAVIVPGATWTDTSGNVIQAHGGGILRVGSTFYWFGEDKAHNSGSFRAVSCYTSSDLATWARQNDALTPVSGTSISSSNIVERPKVIFNKANSEYVMWFHSDTSNYGAAQVGVATAKTPCGPYSFKSSFQPLGAQSRDMGIYQDDDGSAYLLYASDNNQNFKISKLDSNYYNVANQASSIQGATLEAPGIVKRNGVYYLFGSHTSGWDPNPNKFFTSSSLSGKWSSEADIAPQNTRTYFSQNTFDIPISNDFAIYMGDRWRPSLLGSSRYIWYPLSWSSGSPKIVAADVWTLDLSAGTYTAATGTTYEAEKAAISGSAKTMSGSGFSGSSAVGYLGKGGSVTFTVQGAGKAQWVALYYANADSTWRNTTISANGGASVLVDQPNTGGGTVVLSVPVKLNLNSGSNTITVSANQNNYAADLDKIVVYTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI83</accession>
    <name>A0A9P6JI83_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_140360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157960">
        <property type="protein sequence ID" value="KAF9522121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI83"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="37881" checksum="F8CF0C9B3CB35C41" modified="2023-09-13" version="1">MVDWKSPAEIVRDLKVLDKLLHGLFGLYIWEYATSMDFEWEFITRKRQFRWPMVFYFLGRYIQLFAMIASLVSLDSPSALPCQSLFRFILFCGFMSIVISSVNLAIRTIALWGNNKYIIAAVIFAASVQSALVIIITIDINGAWVPTIGCLVTGGESYMSALFIYTMCFNAAVFVLTIVKLAKIGTNANSKRLMTQSKLTTIIFADGLIFFIIALLADIVVIVFIALNLNPILKAMFQIPASIVSTIVACRSVRRLMNFSQGRPVAAFRLSTRNPSSNRNKTSRQSQTIQSPTSIRSSPEVHVQMETFTHIEDDFIKMDKSEFIADTDIKSDSQNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIX0</accession>
    <name>A0A9P6JIX0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_739202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157945">
        <property type="protein sequence ID" value="KAF9522440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIX0"/>
    <dbReference type="OrthoDB" id="3025143at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="429" mass="47815" checksum="7690AC58A7CA2D81" modified="2023-09-13" version="1" fragment="single">AEIEPPRRPSDQPGPCQGSTTEPPRPTPNVTDSQPPTERMMKRKAASQAHARQNKKKKEEKKKEARHLADGVYSNPPPREKANNKYFAMAKPILTNVKVSAADVTSTGFTGMRNPKAELKGVGYEGTQRMLKDKRVYTLDELVGDGSVFGFQHIKWDGKTPRPLVDVDGLLFGVAGGQPNDANWNKQQLGGAKKLSEARETSSNANSDQTPRRGDFKTMRCGISHGGGQTRPMNLKNTGRNLKTIERLNGDLFFRTLAGFTSSVFQHWVPKLHQHYNEELRKLFKHDSSLKPTFETVFTATTYNLGPQTLCLPHIDFANLAYGWCSVTALGNFKHETGGQLILWECGLVIDFPPGSTILFTSALIHHSNTAIGDGEERYSFTQYTAGALFRWVAHGFQKVEEYRKSLESEELAALDKLNSERWGRGLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJK8</accession>
    <name>A0A9P6JJK8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_863001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJK8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="23746" checksum="05A08EF87D9C1D46" modified="2023-09-13" version="1" fragment="single">PLLFDPVSYSQLDTLFSKLKMARIMIAAGLVALLVPVYAGIIPRHLPSGLDTNDIPPACVDTCQSLVNSVQQGCVDDVTCFCSATFVTSLRPCVQCSYDAVPSPFDGTPDQYIQQYSSTCAAAGLPVDGGAASSGSASATGSATASGGTSTSASGSQTATASASTGTTPGTGTASKPASSGASLSNGTTSKSTATTSASGSSGTSGSGSASGSSTSGSSQSGATSITQNMFSILTAVSIIASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK11</accession>
    <name>A0A9P6JK11_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_691071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK11"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="141" mass="15404" checksum="0C6B1793583F22AE" modified="2023-09-13" version="1">MAVKRYPPTNCVFPCCFLRLSSTTSSTSTLVETNFNLQFGGVTSSLNSFNEISFSEVPIQWLNPANLRAKHPLLKAIKIFINPPDIESPSSTNDDAVAGLFIYIEKCLKSLVGSGLRGLPECNLSPIAYNPEVGRPNLKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKD6</accession>
    <name>A0A9P6JKD6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKD6"/>
    <dbReference type="OrthoDB" id="3267981at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="572" mass="62392" checksum="3D75B356975DAE9F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKT7</accession>
    <name>A0A9P6JKT7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157903">
        <property type="protein sequence ID" value="KAF9524165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKT7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="66" mass="7578" checksum="E9AD369FEB3C0514" modified="2023-09-13" version="1">MNVKYLTIFENESRIFGHPAVLFWATFACAGLKALLASLTTLCRTPYTYLCPLSSSVRVYFRFLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKV3</accession>
    <name>A0A9P6JKV3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_773655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157897">
        <property type="protein sequence ID" value="KAF9524566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKV3"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01891">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.250:FF:000001">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="entry name" value="bipa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048876">
        <property type="entry name" value="BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047041">
        <property type="entry name" value="BipA_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21018">
        <property type="entry name" value="BipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="45"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="701" mass="75413" checksum="FD63CF259CDF5DCA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKY2</accession>
    <name>A0A9P6JKY2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKY2"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040136557" evidence="1">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="178"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="32766" checksum="40C6A2E20C0429BC" modified="2023-09-13" version="1">MKTTSQLALLASFLTVASAQTYNIINKCPEEFSIFWNGRAQYTMAANDKRTLVSGPNTGFVYTNYNGGKPNGDNTTRFATLVRDNSSYFFVVKGNKFNTGISVTPSGGNSTTQGFCPAIVCDSPDCNTAFDVAPVAPAGFPPVGSSAPTPPLYSCPGDNVSYDVTFCPNDKFPNEITGVPIHPKGHEDKCWDVRGAVFENGTPVQVYDCNGSQAQKWVIDLGTTKVRVAGTNFCLDRGETPGNGVGMKIWQCYQNQPPQAWVFNDVGTVAASGLCVDVPSGDVTNTNQLQTWECGAENNNQLFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLJ9</accession>
    <name>A0A9P6JLJ9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_859731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLJ9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="65" mass="7684" checksum="783AC8A242263BC3" modified="2023-09-13" version="1">MLIIAKFAISRRHQAQYFHLPHSIPSTQPSFFLQVVLLQKDTPIRIRQKKLRVDNHTITSFLPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLK4</accession>
    <name>A0A9P6JLK4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_818541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLK4"/>
    <dbReference type="OrthoDB" id="3184970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="14"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="296" mass="33893" checksum="F6B7F5DA32A2DA56" modified="2023-09-13" version="1">MNFTTHDKFNSADADLIIISSDYVKFRLHRMNLASYSEGFPGAEVGTAGEEVHLTEPSSVLEVLFLFIYPEHHQQVDLGQLVRKGRSMLALAEAVEKYQVTGAFNHCMKFLRQPKFVHRYPLDVLAHALRHGYPALANAAAVLLYLCEPKDIIERLTDHGAYLWLKYRERCRDTIFKVAEDYLENMQITKYCITIKAPFQVCSVCRTCLLTWFTYLQTISSELKLLRELATLESYPTNINHTFCGSECMYGNRCDHALQMAKMCGEGLREITKQPFVVDPKAEDPQARKLPLVELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM98</accession>
    <name>A0A9P6JM98_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_870758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM98"/>
    <dbReference type="OrthoDB" id="2014058at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008699">
        <property type="entry name" value="NDUFB8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16968" checksum="762547CF1365BEA8" modified="2023-09-13" version="1">MNTQQVVRRGLVVTRWANRQALAASNRRNYVTEQADPQLNGYPQLPNTSRQYLPPVGWQDNLLRKNFGDTLHEREELYSMWGPDIPPISPYTALGHFAIAAGSIITAGFFIKYILLPDAPVARREFPYGGLVKELGGLDENKARPLSDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMK7</accession>
    <name>A0A9P6JMK7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="9">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_908886</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="9"/>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMK7"/>
    <dbReference type="OrthoDB" id="3781271at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040466755" description="(4-O-methyl)-D-glucuronate--lignin esterase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="4-O-methyl-glucuronoyl methylesterase-like" evidence="11">
        <location>
            <begin position="95"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="40890" checksum="1704B4F149A0CE03" modified="2023-09-13" version="1">MFLITLSVIFLAAQRVYSQCTPLPTPLPRFGSLTATNVLPNPFVFYNGTAVASPADWNCRRQEIKTILQEYLFGYYPDHSKETVTATRSGNTISITVTAGGKSGKFSATLALPSGATKDKPAPVMIVLGFGDSTFVSNGIATATFDAGSVAADSNSKTGAFWSIYNGQDVGVLLAWGWGFHRVLDALIQVAPEVDPKRVGVNGCSRYGKAALAGGIFDDRITVTNPQSSGVFGVSPFRFRYESGGWNERLESNVNGAGWWTKSNLKEFIPDEKRLPLDSNFLASAVAPRAAVWDNGQGDAQMNPEGVAGVTFPSTQAVYKWLGATDNVGLALRSGGHCDPSGTSNDIDFIKSILLGTTRTKNYANTSPYKAHPETYPWLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JML1</accession>
    <name>A0A9P6JML1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JML1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="141" mass="14854" checksum="A2B2C361D2739DD8" modified="2023-09-13" version="1">MSAPKSSSANTAKAAKELQDALNGFNALDIQALTDESVPVEKRAGVAKKASGDVLKAINKLDPLLKNAQGNKEIQDAQATLRKAKVQFTGLDSVLTNIHENEGGVEAFSFGDIFSTIKDVVSHPIVQALPGAIWSVAKTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN19</accession>
    <name>A0A9P6JN19_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_884643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157866">
        <property type="protein sequence ID" value="KAF9526922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN19"/>
    <dbReference type="OrthoDB" id="5389493at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109:SF2">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42109">
        <property type="entry name" value="UNPLACED GENOMIC SCAFFOLD UM_SCAF_CONTIG_1.265, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="294" mass="32686" checksum="F6477A59671D9029" modified="2023-09-13" version="1">MSSSTINYAHFTGYDSLPAAIAFAALYTPLFFWFLRKSFTHPTYVHFVLTFFCLIRVVAFIIRAVLAGSNNAGTNLGLVIADQILLGVGYFGLLYSAYTLVLDLEQATNKVQNTRENPLITLTRNRRLFRFVMTIAVALGIAASSSVKSDGSLPSSSTALREASTIIFLVMTALLVLQTLYFARVKMLNRYTAVHNPQASVNPGRQDRFGAKHGIFILMVISLLLLIREIFITATMTPSSRWKQYDEKYWYPLVSTTELLAAICYLAPGLVPSAKEINQRAAEVHEGHELKESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ70</accession>
    <name>A0A9P6JQ70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ70"/>
    <dbReference type="OrthoDB" id="3233595at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="17"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="354" mass="38681" checksum="130421F0A0A29965" modified="2023-09-13" version="1">MSIKSTQIALVIEEKLGPFVLRDVPIYTPGQGEVLIKLHASALNPADWMIQKSGLMITKYPAILGLDLAGEIVAVGEGVQSLQRGDRVLTISRFIENQFMGLQQYSLANEVTTAKIPDNISYDQAATLPVCFSTAVTGFFADFHMALHFPFLPLKRRESIQGNPLLSLLDLLQWGSLLLAIQLAKLLGFLPIIATASLRNTDYLKSIGTTNVLDRNLESADFDKVVHEITGGRPVEYTFTALSIPQTETLALAILPKDGMLISSSPNVSDILKKADFKIATALATPTVPWNKELFKTIFSEKLTSWLEKGDIKPNRVEVVKSGLAGVVKGLKKLEDNAVSGFKIVVRPLDTPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQL1</accession>
    <name>A0A9P6JQL1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_868935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQL1"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF23">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="77"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="22166" checksum="D47ACE4744EF20D6" modified="2023-09-13" version="1">MSLSDDVKQDLLLACRHGDLEDVQTFVTQYGAEILLETRDDNGNSVLHMISANGHVGILDFLLPLLPSSFLATRNNSGSTPLHWAALNSQLEIAQKIVRHPGIGVDLIDVKNEAGRSPLGEAELAGWDEGARWFVEVMNLGAESGHETAANEEVLDSDTKDIEVEIEDADGKIAKMTISGRARVWVYLPSCWVCYLPGKLQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQR8</accession>
    <name>A0A9P6JQR8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_851910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQR8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="213" mass="24028" checksum="CF681D5EDE18DAC9" modified="2023-09-13" version="1">MNLNGFRQNGGLHEHSNNSKLTCCSTIKSQLLPEWMFGAWMVETEAGVGNRSAGPSSAVVRCAKKFLRSTCARGRNFRPHSNSRHLAFLINFVSSLIYHYQRFLLQPHGTHVHLPNSSTSCFKHTYTYAAQLSNRGQGTIGTPNFRVFNFKKRAIVSEKSMITKIFSDDRCLRIRDPTNIQRLPYGVLVYHYTFGRLGSVVPTASPLDGYLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRD1</accession>
    <name>A0A9P6JRD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_259893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRD1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="112"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="554" mass="62469" checksum="197D3ADC6CF846BD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRD7</accession>
    <name>A0A9P6JRD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_893550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRD7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="277" mass="30767" checksum="F74B3739D8901D36" modified="2023-09-13" version="1">MALLYNTFDSCWPSAWTIKSVDPPSMFGTRLAMLGETEIIVWDFVTGDLARWRSMSRCTLSTTLHCVYAVAHEVVIQWELPPMSNLADAANPLLGHDPCATYTIIFSPDTGSAIDFEDDDEASIYYRTTSCPPNSWNQNPDSQFLIVLRENDLAVDKMETFLQKSASTHSNARLKEKIFPTRIRRDLSSPARGSSVDILSAPTISDRNLLFASFPVGEDVGKVYVYVAPEDPSQDITETILRWPSDRAGRISLSSFCPVTGRLCLLMGGDVLILDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRG2</accession>
    <name>A0A9P6JRG2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_926294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRG2"/>
    <dbReference type="OrthoDB" id="3143151at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="157"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="905" mass="103612" checksum="A6A96AE9A42F4F4C" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRS4</accession>
    <name>A0A9P6JRS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_924970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRS4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040283368" evidence="2">
        <location>
            <begin position="22"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="188" mass="20954" checksum="934BCAA4690EF271" modified="2023-09-13" version="1">MHFNAHLLTAVLLASFQLVASRPFWRKDQELHYRDMALTVDDILVARFKQGKDRDSLHPQHPPQTTLHERPDAELRQVAAQVLHHAGPRTNTVREDAARGNAARWDTARADAARGDAAMVHLDVDRYGGQRTTPAAGNSPVGSPPRSPLIPPHSPVGSPPRPPNHAKRELMDVIESILERRGWHSDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS05</accession>
    <name>A0A9P6JS05_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_194319</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS05"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF31">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9530314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="374" mass="41602" checksum="FFCC4F54AB8AF30D" modified="2023-09-13" version="1">MSTITIKAECHCKSNAFDVCFLASSLPISAPMCHCNACRHSTGQIFTQCLPIQSAPLTPNDTGNFADLQYLQQYQTTSASSNWFCKKCNAFFFATFQDSSGLLKWSVFPGILEKIEGLFTTAHHEFVEETCDGGKADHYRRPHGVEVLHYQTTSTDGSVLPMNWTNEHVSDVFIQPLADDATFNAYCHCGSIQLTIGRPLKHVQPNDGPFAVKPNPVSIQPQHGLRYQAAHCFCTSCRVTSGSTITSWGFAAANHVIDRKTSKPALAFNPEGSPFFVKNIEGTNQYESSPNKFRESCAKCGAHVFFWDATRPVGFIDVAPGLFDQDAEGSRVERYFAWTRTLFDDDALDRKVVKDLRDGMQEYYGVPSGIWPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSB1</accession>
    <name>A0A9P6JSB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_176153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSB1"/>
    <dbReference type="OrthoDB" id="3225366at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="286" mass="31272" checksum="42A2B2FB5C9CB749" modified="2023-09-13" version="1">MSATPLDYRLPSTVKSIQQGWLISCQSSAVISGLLSVISLILLLFFEEKAGQLDNATISRALNILGYTSFLLNISACTTCFIILDRLGDVPFRAAQNKGDGPPDAKISLPSTGILREYGIGALWRWIVWHWLICFLCGFWAILAQILIFAWVQTSSQTKIVVTCIAAFCLLPCVAFILAPVINGLSNIKGREDLEASPGTPVLPLPHIGRPLSGIPHTPIAYQASFPQLRSPQGVAPPTPSLTSQRSQLQLQTTFSPPQSPADPYTPRDRKRTIRKSMGEKTFPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV62</accession>
    <name>A0A9P6JV62_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hamartin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_480311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV62"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="590"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="931"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="687"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="823"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="108081" checksum="0464B80832428A42" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV97</accession>
    <name>A0A9P6JV97_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_902237</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="4">
        <location>
            <begin position="2394"/>
            <end position="2948"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="3">
        <location>
            <begin position="3186"/>
            <end position="3517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2960"/>
            <end position="3014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2975"/>
            <end position="3003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3559" mass="403077" checksum="B60FD17FC0293173" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW40</accession>
    <name>A0A9P6JW40_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_843599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW40"/>
    <dbReference type="OrthoDB" id="3009566at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12061" checksum="66598BF1E36454CE" modified="2023-09-13" version="1">MPEVEGFIQTTQEGTHFLATFVIKDAEYNFSGRISSNTQQWKCKPAFLEYETLAQLTSTRPFDGKIGRRKVELKISNGPKIVGYVLLPLEEGSSVSGNGMWNTGARMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWJ8</accession>
    <name>A0A9P6JWJ8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD repeat-containing protein 61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_843562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWJ8"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="236"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9535144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="34008" checksum="9E59E6D5C45DFC93" modified="2023-09-13" version="1">MSLAFLHAHDCSEPHSDAIWGVVWTQNDTAISASADGSVKQWSGAGVPHPPNASFPKPHTLAQVSLSVSPDGKRAIYNSIEGLTTLWNLENGEVVSSFESYARNSEDAEPSWSVSLHPQGENYASTGSSGNVIIHSAQPNDFGHTLSTLAPGRQKFGMFCKHSPDGRKIAMSSETGQIYLFDLESSSLSMTFTSHAMSVRSLTWSPDSSLLLSASEDKRLVLHDVRTAPGGAVASFSGHTSWVLSADISPDGRLGLSGSADKTIKVWDIGARAAVSTIPDTGEVWSVSWRPRPAAVGSPGAFVSGGEDGVVRWWRGAGSGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC61</accession>
    <name>A0A9P6BC61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_778810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158089">
        <property type="protein sequence ID" value="KAF9521387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC61"/>
    <dbReference type="OrthoDB" id="2682806at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041457">
        <property type="entry name" value="CxC2_KDZ-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18803">
        <property type="entry name" value="CxC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxC2-like cysteine cluster KDZ transposase-associated" evidence="2">
        <location>
            <begin position="11"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="906" mass="102282" checksum="CC5E835AFC96ECB4" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BCA0</accession>
    <name>A0A9P6BCA0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158051">
        <property type="protein sequence ID" value="KAF9521474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BCA0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="333" mass="37129" checksum="9CBF8B2F17A2814D" modified="2023-09-13" version="1">MALLPLQKGRQLSLKNLQALVTMVKNPKRYQVNVLADPDAMVLKIKGKFDDRVFAETVAEALLSDVICKLTVGSFSKNKDRKGDYLFHQLTGLDNAGEIVDWESALARLSVPYRAFVLAIRVGNADDRMSHLGERLTINSFKTFGHGVRTDPDEITTAEYNSGAQTSRVIDHTGDDDDEVTCTGTNVRQTTPEDDSIVVLSSRLRQTGIPKNMPPGVNYLRARIPSYHIKCGTHIVRVFVSELVYPGDVASAQPGDVFVLLDPPTVFVQGSKRWTVWDWCKKAHPIESLRLLAFSPDGPVYVTKGERKKHRGTWIGSVETAVAEFRKKSRKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2Z4</accession>
    <name>A0A9P6E2Z4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158025">
        <property type="protein sequence ID" value="KAF9521563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2Z4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18488" checksum="DF85A38B1ABAC0B4" modified="2023-09-13" version="1">MSMLSERMCSDRARESSKMLRPLIGPKGASEGRGKPRKGAGREPIYWLSKMRPKQPTQYLRRAETLRPAVKHSALDNVVLLPANSGLAWIGYIRYHLAGTGMATKPIYLLDYSINQLIVERKRQSKFKQHRYKPAWKVPSNEQRYEKKGEGKGSGDWGKCQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3M5</accession>
    <name>A0A9P6E3M5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_777889</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157976">
        <property type="protein sequence ID" value="KAF9521895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3M5"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="129"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="129"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="339"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9521895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="520" mass="57090" checksum="129D58853411B172" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4E8</accession>
    <name>A0A9P6E4E8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_864658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157951">
        <property type="protein sequence ID" value="KAF9522312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4E8"/>
    <dbReference type="OrthoDB" id="2105912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17324">
        <property type="entry name" value="MFS_NepI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910">
        <property type="entry name" value="TRANSPORTER SCO4007-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="90"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9522312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="507" mass="54662" checksum="705620EBF4202239" modified="2023-09-13" version="1">MSSASSITIEDATPQERDPQHLAQTSAETVQDVEKNDNTTSTVAAVVPETPIEKSVSVDTHRFDFGFLPIPPSCRYDPDHPPPFPFWKTGIFAAASTFSTSAMNLYYCQPLLVELANNFKVDEIVISRIPSLLQAGYAVGLVFISPLGDLVRRRQLLLVLMITAGALSIGLAITNSFVAFEVISFFVAIFSVTPQVLIPLTADLVPAQRRATSIAIVLSGLLMGVLLARVLSGIIAEFSSYKNVYWMGVAGQFLLISAIYFICPDTPVKNPDLSYFNILWTMAKYATTEPQLIQGCLIIFAGSAVFAGFWVTMTFLLSGAPYHYTTLDIGLFGLVGMLGVCTAPFVGRAIDGFVPWMATGVAIFLIIVSQAIETGAAKLSVGAVIVSTFVLDVGIQACQISVTTAVFAIAPEARARLNACVVLSIFLGQVMGTSVGTQLLVEHSYEVSSGVRLAFCGWQILILLLRGPHVPRKTWFGWKGGMQMRKKPEVVEEAPASGTVTPENKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E528</accession>
    <name>A0A9P6E528_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_91465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157937">
        <property type="protein sequence ID" value="KAF9522689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E528"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF56">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="700"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="814"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="723"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="741"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="761"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="817"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="862"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9522689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="959" mass="105588" checksum="93DEB3F0EF5B05AB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E591</accession>
    <name>A0A9P6E591_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157938">
        <property type="protein sequence ID" value="KAF9522669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E591"/>
    <dbReference type="OrthoDB" id="3258555at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="360" mass="40612" checksum="765B23381C22B1B1" modified="2023-09-13" version="1">MLPPDFVVLDSSFILGPNSIWWRTQRIKCSIILVCRAWYNSGVAILYRDVDLRHFPELLNFLRSLKESTTNLGELVKSLNVSCLVPTTIGLQFEQLIQAIFKLCPALTSFTTAGSGYTPPGSGYRTSDLASYPPTITHLTLGELLSYTTLLDILGELAKNLIYLNVHINSTWVYYTSSNELLELLEAHGENLLFLHVHFGCPSAMVTALDLCPQLERMVTSPTFSLEDDDNSPLFHKQLKWIMYRALEQFYPSWVRGAQDEFNIKVFEFRFRHDVGHPSWYFDLGEDNIAEVGFQTTEARETCADWHSDTDSLCPSAGSDTSSEVSGGSPADITEEYLQFSDQPIPFDNLDYITSLLSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5F9</accession>
    <name>A0A9P6E5F9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6535 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_776354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5F9"/>
    <dbReference type="OrthoDB" id="3235960at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045338">
        <property type="entry name" value="DUF6535"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20153">
        <property type="entry name" value="DUF6535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6535" evidence="2">
        <location>
            <begin position="46"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18078" checksum="EEEEE7FBBE76FA8B" modified="2023-09-13" version="1" fragment="single">MRRDKARCDAWKDEVQNLLIFAGLFSAVVTAFVVESAKSLQTDPAELINIFWFMSLVLSLTVVLVGIISLQWLREHQKYDTSLSPQQAVGIFNMRDEALSQWHVPAIFASLPLLLQAALILFFVGVIDFLQSLSIIVMIPIAALLLCPISFMVVTTTLPTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Z6</accession>
    <name>A0A9P6E5Z6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Z6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="16557" checksum="973AA34D64F86D5F" modified="2023-09-13" version="1">MKKDVGGKKRDVKTKGKGKEKARPSSPTAKVDLCKLLDNAVLLGQLDRYPSPMEDSDAELESAVALSTIDYAPPPTNVPRSLEGNSMGEGSSTTQFHRTDTEDNNVGATMEAPAQTQRLQFLDLTSDGNMIVIEYDIDENGVIDLTGNEENKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6M1</accession>
    <name>A0A9P6E6M1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_862741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157916">
        <property type="protein sequence ID" value="KAF9523467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6M1"/>
    <dbReference type="OrthoDB" id="3046363at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="62904" checksum="81C3F2A14773EFFA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7G6</accession>
    <name>A0A9P6E7G6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_886491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7G6"/>
    <dbReference type="OrthoDB" id="2913301at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="53227" checksum="EBFE545C6C1E18A0" modified="2023-09-13" version="1">MENHKRANKHHDPLQKVPPEITSCVLELAFEPKSYMDRIEPDGGYTYARCPLVLGGVCSYWRATAWADPRLWTHVSWILNPTHDDPNLFRHRINLFKEYIHRAGALPLHISIVRDETKDLEISDFAAEILADTINTCFYRCRRIALDCPMEVLGKISVQPITQPILQSLGLLITDHDIDDRRLPDLTQVTQNLEYLELHNFSISCLEAISFAFASFDIVFSTIPPRSPLTLNALQSLSISDTYITSTSMMHLFNCLTLPSLKDLSIFNLGQGGVRMLQSLVKRSNCNLTRLSLTRFNYSEHEFHQLLLGLPGLKQLQLAQPSNLSIMQMFGVVFHQYLTSFDGARHRPFLHHLEELEFISHWQAITGWNTILKMMDGFLDERLNDPPSNLQAASTHKFSKFDATFPWDTASPESSGITYLDNEVLDLVQKLNGRGVEICIRTIGSTGIVELIPISIQHRRSRVQDSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8E5</accession>
    <name>A0A9P6E8E5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8E5"/>
    <dbReference type="OrthoDB" id="3062980at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="378" mass="42168" checksum="FE8A4D93F74E9D1D" modified="2023-09-13" version="1">MDYTEEDLSNLTKKQLAAIIRPQIECWPTPIFNFSKTKLQAMKDAILDKKNGFQKPPSQADGPLNNPQLQPERNAPTAAAQNQGIGGDDDENEREENRQEQDPEPHITIDVFLEDERCMPLRKSAIQVTLPARMEVESASKDRCVLAAPLMAQIQTSHSAIRGPARLAFPFPRRPSFRTYFAILDRRDEDLAQAVCNPDRVCFTDESSIEIYIEPVPDAESGQVSSATPSQSAAAPAVSLLPAAAQTVHWLYSQALLADGYQLFADSRSRVLQNPDIVRVWKFADDFHHEHHRKTHDTPSGTARITKQIIQEALDIRETSLADALNGMKLIKLYGAGGTDEADDVVKELGQNREKPLGRLALLQFLQQWQKSHPVSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8F0</accession>
    <name>A0A9P6E8F0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_909930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8F0"/>
    <dbReference type="OrthoDB" id="3231781at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="165"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="293" mass="32813" checksum="BF1416488E378E65" modified="2023-09-13" version="1">MPANPLLSPQQALLVSGIANSFFFGVLTVQVYNHYLAFPQESLQLRFVVNAIYLLQTFEAIVVYYRDYLQLALAGTSSTADMAGKTSGIELVITAVTMSTVQFYYANSIRLVSKKLIFSWLIICCSILQLQAGIALAVMTFRQVNSPSSGRVARYESLIWHFANAVCDVMIAACMTYYLMRYYSHTQRTQRIIKRVVWWMVKTGTVITIVTLGCSSLFFSAQNHSNFNTIYTSIIGALYSNSLLALVNGRVVYRVRVDRPPSALAFVRPMVPQSEDELSVFDVRKNSAEGLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8U8</accession>
    <name>A0A9P6E8U8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_773474</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157895">
        <property type="protein sequence ID" value="KAF9524676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8U8"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034458">
        <property type="term" value="F:3'-5' RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040468201" evidence="5">
        <location>
            <begin position="22"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="103" mass="11153" checksum="CB356963BD2C9878" modified="2023-09-13" version="1">MPLGTAFAILLTKNVVTIVVGETGSGKTTQLAQYLYEDGYCQHGLIGCTQPRRVAAMSVAKRVSEEMECKLGGTVGYAIRFEDCTSADTRIKCEALHPSFSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8Z7</accession>
    <name>A0A9P6E8Z7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 95 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_574439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8Z7"/>
    <dbReference type="OrthoDB" id="2848340at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049053">
        <property type="entry name" value="AFCA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016518">
        <property type="entry name" value="Alpha-L-fucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054363">
        <property type="entry name" value="GH95_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027414">
        <property type="entry name" value="GH95_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084:SF3">
        <property type="entry name" value="ALPHA-FUCOSIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31084">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14498">
        <property type="entry name" value="Glyco_hyd_65N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21307">
        <property type="entry name" value="Glyco_hydro_95_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22124">
        <property type="entry name" value="Glyco_hydro_95_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007663">
        <property type="entry name" value="UCP007663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 95 N-terminal" evidence="1">
        <location>
            <begin position="68"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 95 catalytic" evidence="3">
        <location>
            <begin position="364"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha fucosidase A-like C-terminal" evidence="2">
        <location>
            <begin position="807"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="882" mass="96574" checksum="CF04FC1E6A140733" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8Z9</accession>
    <name>A0A9P6E8Z9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_946325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8Z9"/>
    <dbReference type="OrthoDB" id="3219336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="133"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="28"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9524707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="31137" checksum="F3EF9A51C6731877" modified="2023-09-13" version="1">MRPTISTNSEIIELTSSSEDEKCKKDSLVTARKQLRDWKEKAKDYKKRLDVVTKDISIVRADQEAKLEEASREVARIRAEHDSKIAEIAEVFNALNSGHEQEMDSAAKEISRLQSLLQMSCKKNEELLELLECDICAHSIARPFTLKNCGHTFCYNCLRGWFLVLREEFKLKHPVYDPVHRFEKLNLATASQLAQALAKDYSNFVHQVTLEDVLPHALRQYPHYSCPLCREHVHSKPVEVYTLKAVIPLLREVVDSNHKAEGQWAEFFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E903</accession>
    <name>A0A9P6E903_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E903"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="101" mass="11447" checksum="E4D1A40D9611405A" modified="2023-09-13" version="1">MNHSLRISQLAFCQSSFLCLPVCCDRSIFIRNPLINTVNAPISDMSFGYAQVSKLGSNPNSFRLERFVNVNLTPAHYRVVNNDHQISPSTQVILGLRLYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E970</accession>
    <name>A0A9P6E970_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase like family 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_909817</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E970"/>
    <dbReference type="OrthoDB" id="2849215at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06434">
        <property type="entry name" value="GT2_HAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="430"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="556"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="579" mass="65600" checksum="74C4BFD206342F42" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E971</accession>
    <name>A0A9P6E971_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E971"/>
    <dbReference type="OrthoDB" id="5397701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331:SF1">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="28950" checksum="F22318D5596A7F83" modified="2023-09-13" version="1">MQTSSSLFRAATNQFSTAHLRCSRRSLQQFSCVRFSSSTSWPQLARSQPCISHKTLPRPTRRTYNSHVSHTTDVVFDDPHRPDLFYHLVKAPTPLSSLQPAYALSFLREPPPHVDSPVIIGWLPAQTIQETPSNAGSPTQERGASLQDFVGNPKFITFLHDTIRSGLKESVDEIWKDAALQYQQGWMHIHDQRNPPDQGRIGDPDDIIASVLVEDSVLRPETYQPMPSYRICTSDGVIQLTPGLSEYLRKALRKCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9F0</accession>
    <name>A0A9P6E9F0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_838559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9F0"/>
    <dbReference type="OrthoDB" id="3166422at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51802" checksum="92E8E3129DE13FB7" modified="2023-09-13" version="1">MSTSTSSRIPDSHGSSNAEYCNLKVNQPQTRTEEFEHEPNDASLAQISVDIEHKSRLSATTPLRNSRYTQRKLPPLCSGWKQHIHPDGKPYYRNASRKILTELDVSDVEEEKEMGQIYEELIARYNLAMVTQQEPGTLSDETEIYLTRNTTTREWEYYFVDYSTEDVFWVEKMDLRRLIGDRYPTDVNYHLCLLRNYYSHIENFPCHHTLPRDAEDNLRAALIFTCADHLTSGEDATSPWTPESAKCFLEMLDSFRDNTTTFKDQLYGSGYRSCFFSYQYYQRRLDDVWGSKIVSSLGWQRLVLALLKEWSDSNLLATVTLSANIAFLALPGIVNPPRFCSLLSTFLCLRSILSGLHHVWIHRFRAEAAPATASMYFQQAERFTGTLKPLALFLALPITSLLWGLCWFAAAVAAVAAQAVSWGMGGQLLGNVAGIGVAFLIVLVLMLMVYGFFFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9X0</accession>
    <name>A0A9P6E9X0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9X0"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="44720" checksum="B31084261DE414BA" modified="2023-09-13" version="1">MSLLQLPAELLDAVLSYLWAENDIISLWQCSLTCRILVSPAQAFIFRNLKINFPSTIAPAILEYRPYILPLIQHLELIEIHKPWVQNCEAIQRLLKMLSPYVTSLELIQRRPNVDKPRFELSSLWQLKCLEKITLSEELQGANFGRPMHDNLALSTFLNHFPKLRAITFSSCLVPIQIIDKRNPKSSPVFQLEYLKLKYCQDMLTLDWLVPAMVSLRNLHFQIPRAVDQPLFYDILFRMIKISASSLERLTINGVNLIDKAHLQFLMDGIRIHNNNLCSMNLIMSKGRSQTDQMSSIIHCLQTIGPLPQIRYLVIGLYQTILDGATHLNDLEGLIVSPNFPELQFVEIRPILMNLDVEAFSPGVLLAAFPRLTKKKMISMRIAGKYDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAI2</accession>
    <name>A0A9P6EAI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_908900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAI2"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="103"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9525791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="225" mass="26213" checksum="14079C4EC6498977" modified="2023-09-13" version="1">MSSAQKPIFVYTGVTPNGFATTILLEALKSINPGFDYDFEKIDIFEYRQKEPWFIELNPNGRIPVIIDRSRNDFKVFESSAILLYLALHYDKQHKYWFNPETEPNEYSDMLQWLFFAHGGIGPMQGQLNHFNRHAPDIPYAKKRYNDETKRLYGVLDIRLKDRDFLAGAGRGKYSLADIKAFTWVRLHGLARIEPMDEWPNVKAWLERLNKETSVIAGVQVPPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB70</accession>
    <name>A0A9P6EB70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_770862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157875">
        <property type="protein sequence ID" value="KAF9526166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB70"/>
    <dbReference type="OrthoDB" id="3236755at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="34480" checksum="BF6314EC1E3E1B5E" modified="2023-09-13" version="1">MSDPLFFINPNALSFNIKLPAKESAKPKVPPGIRSPNTFLEVGKYHLHLLVIEIENGSDTFLSQWKDKPAAFAKAYQSQFTAYAQGMFPFNLPLGAGQPPLEWWQSFEATPDGGILAAITIKLYSAVPHSMADERTMSFVTMLNSARRSRQKVETIIAMAQVRGYYQAENGVKVCLIFFSCYVTNPVFLQHRRSSRPRPTVRFFDVKRLLRSIDEDERDDDPNYDKSDDEDDVPSFRTTTASPSAPLILSESSTSLPGEGDTSELDFTSPIVIEILGDGPVVKKGKPSMASKASVVDEEIGGTFELQEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB73</accession>
    <name>A0A9P6EB73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB73"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6957" checksum="08B78A0D52BA2BEC" modified="2023-09-13" version="1">MRSIIFIISGIYHQSPPHSFQHTPHSSPHSRKLSFSHWHLYLYPRILTLIIQIRFYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC33</accession>
    <name>A0A9P6EC33_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FGGY carbohydrate kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_769830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC33"/>
    <dbReference type="OrthoDB" id="203824at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019150">
        <property type="term" value="F:D-ribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019321">
        <property type="term" value="P:pentose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07782">
        <property type="entry name" value="ASKHA_NBD_FGGY_D-RBK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006003">
        <property type="entry name" value="FGGY_RbtK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01315">
        <property type="entry name" value="5C_CHO_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43435:SF4">
        <property type="entry name" value="FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43435">
        <property type="entry name" value="RIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="4">
        <location>
            <begin position="2"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="5">
        <location>
            <begin position="296"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="66697" checksum="115AEBABDBA9A0E9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED95</accession>
    <name>A0A9P6ED95_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit Tim17/22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_768615</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED95"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="15844" checksum="99D708913ECB8394" modified="2023-09-13" version="1">MSSADHTRDPCPWVILNDFGGAFSMGAVGGGIWYGIKGARNSPRGERFVGAISSIKARAPVTGGNFGVWGGMFSTFDCAIKGWRQKEDAWNAIISGFMTGGCLALRSGPRSAFNSAVACGILLGVFEGVGVLMGRVFSEGARPQMAPSQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE21</accession>
    <name>A0A9P6EE21_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amp dependent CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_894939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE21"/>
    <dbReference type="OrthoDB" id="6509636at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF422">
        <property type="entry name" value="BCDNA.GH02901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="459"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="571" mass="62295" checksum="CE800F2FF6826DF7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE30</accession>
    <name>A0A9P6EE30_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS0</name>
        <name evidence="10" type="ORF">CPB83DRAFT_856448</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE30"/>
    <dbReference type="OrthoDB" id="414863at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000010">
        <property type="entry name" value="40S ribosomal protein S0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03015">
        <property type="entry name" value="Ribosomal_S2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032281">
        <property type="entry name" value="Ribosomal_uS2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027498">
        <property type="entry name" value="Ribosomal_uS2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16122">
        <property type="entry name" value="40S_SA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS2 C-terminal" evidence="9">
        <location>
            <begin position="204"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="225"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="260"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9527377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="297" mass="31999" checksum="B577B271DC586B7A" modified="2023-09-13" version="1">MASKLPSVLAATEQEVQLLLAAQCHIGTKNCDKQMEPYVWRRRADGIHLLNIGKTWEKLVLAARVIAAVENPNDVCVISARPYGHRAVLKFAANTGAQAIAGRFTPGSFTNYITRSFKEPRLIIVTDPRVDHQAIREASYVNIPVIALCDTDAPLQFVDVAIPTNNKTRHSIGLIWWLLAREVLRLRGTIPRTPDGWNVMVDMFFYRDPEEVEKQQQEEAQAKIAAAAGDAEVPAGASEWDVPSGHAGGINPALAGEGGALDWAADAPAANTDWSAEPAAGGWGADTAAAGTTSGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEP7</accession>
    <name>A0A9P6EEP7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_884172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEP7"/>
    <dbReference type="OrthoDB" id="3256387at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="741"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1231" mass="131913" checksum="CFD175D852F8DC4B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EET6</accession>
    <name>A0A9P6EET6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_855534</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EET6"/>
    <dbReference type="OrthoDB" id="429467at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050403">
        <property type="entry name" value="Myosin_RLC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23049">
        <property type="entry name" value="MYOSIN REGULATORY LIGHT CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="210" mass="24188" checksum="86B9F901214B3664" modified="2023-09-13" version="1">MSKYPDYLSPGSTPSKLSKSQKSRARREPSGVFSLFQAPQIQQFKEAFQLIDHDKDGWVNESDLKEIFASLGISPTKRMMEELLSARPGTHSRQSSAYSEEGGADRGINFTMFLTMMSERLFEFDTEAELLEAFSSFDENDSGMVKVDEMKKWLSELGERMDEQEMERLFKGSFTDRQGNFNYREWVKVLRVNDTEEEGNNNNVNNNNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEV2</accession>
    <name>A0A9P6EEV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Autophagy-related protein 15</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_854682</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17855"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEV2"/>
    <dbReference type="OrthoDB" id="58570at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005775">
        <property type="term" value="C:vacuolar lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034496">
        <property type="term" value="P:multivesicular body membrane disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046461">
        <property type="term" value="P:neutral lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050805">
        <property type="entry name" value="ATG15_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175:SF2">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="20">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="382"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9528233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="470" mass="51609" checksum="6C2A309C97AA4F0F" modified="2023-09-13" version="1">MLLGLPVTLQSLISTFLWNTAPDKPQTAAITFQLRHHHGISNNSRILFSDFQRDTSFLGYDSEFIIQTSRGSVARPKTLEAFTGSRRSRIMGLAPVVAWDDWEVPIPDVTKRSTLYQLAKMAGNSYFPDLNSSGWYDVSEGWKSNPHGWLPEDDGLRGHIFVSNDNTSVVISIKGTSATWPVGEGGPTAPRDKLNDNMLFSCCCGRVGPTWSPVCGCYSGGYKCDENCIDEALKDDGLFYPLGLNLYNNVSYLYPNANIWITGHSLGGGLASLMGTTFGAPVVAFEAPAERRAWQRLHLPIPPSTKHITHVYNTADPIPQGTCTGIASICAIGGFALETKCHIGQVILYDTVSKLGWSVDARSHPIKVVIDRLLSENADWKPEFNSESEDGKEARRQHGWGWIPWPGKKHEDDPKEEPGTLREVPRARPAVEVEGEDGVCTDCFNWEYGSFQNLSVAVRPTGCGMASGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEW3</accession>
    <name>A0A9P6EEW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_907374</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEW3"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="7">
        <location>
            <begin position="54"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="162"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="472" mass="52808" checksum="600333AB03547892" modified="2023-09-13" version="1">MPTNSFSARVLQSHHTTSSTHSTHSGNSSDVCAKLITRRKGRKEAIMLRLSRLAIIGRDPEQSTYVVDDTLVSGVHCKLYAISSPSEGVIISCQDVSRNGILLNGQPMRKTAVILADGDEIRLPNSLSFTCVHLWKKSNEKLGLFDPTPPPQPIQKEIGNYIVTSQCLGTGSFATVHLALDPANYRQVACKSIKTKRESEVNQVMKEVKILMTLKHPNINEIYDTEEHKGFMSVFFQFILLYEISYPLGSHIFLQLCTGGDLFTHITHSITHGPRICEAEAKYIMFQVLCGLKYLHVKMISHRDLKPENILLHCPGPYPRVLIADFGLARPNSYQETFNVCGTVSYLPPEGILALDNKHLSYIGMPSDCWSAGIILYIMLSLRIPGVEAATRSGIRSQSDLKLKERIIQGDVEYFDDPWQQLPDARKLVEDLLVHNPVLRATVDSALQSIWILSESDELKALYRHRVGDLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF64</accession>
    <name>A0A9P6EF64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ras-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_363170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="28245at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF142">
        <property type="entry name" value="NEUROFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="4">
        <location>
            <begin position="1311"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2629"/>
            <end position="2648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2629"/>
            <end position="2638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2697" mass="300677" checksum="DC617BCCF87F13B9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFG7</accession>
    <name>A0A9P6EFG7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_767806</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFG7"/>
    <dbReference type="OrthoDB" id="4454541at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="754"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="907" mass="100547" checksum="4F2DEA58EB8B3CB4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG08</accession>
    <name>A0A9P6EG08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_791868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG08"/>
    <dbReference type="OrthoDB" id="3365698at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50915" checksum="88EABF96C0325131" modified="2023-09-13" version="1" fragment="single">MKQEPGEKHGDGQDMDNPLSNEDNRWLSLPLELTTAIFLVCHATDSTVRDLLEGVNSSQTRLPTEFVLSSICRDWRSLALDMPDLWKRFIYTPSGRVDCPPEKLELYEGRSGGQLEDIYLNFLSGSSEDDFYGFLNDLLQQHNQSLRRFVLIGEGGLEMGSILTEVFKDASMPNLEYYAVVSDMVLDVAADLVEIEFLNTFQFTNGAPKLKYLYCNGVMAAWGLPPTNKLTTLRIEGGEPQCTFSLDVLHEVFSFPLLENISLSIPEIVQYTPEDNPNSPITARRLRNLRLCNTDLDDDLEPGFTQFRFEDLLLVLRAPALEYVTLKNFSAVALNKLQASSKSFPTVHDLILINCDTSNPSHCLVFKTLFPSVQSLTVWGNSGTMQLFAMWPSLKRVTVDDVFSPGIVSWPEPTSNRTLRVPRRTYTPWKEANEQRHLEMIEPMEIEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EG77</accession>
    <name>A0A9P6EG77_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-reducing end beta-L-arabinofuranosidase-like GH127 middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_854495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EG77"/>
    <dbReference type="OrthoDB" id="5358475at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049046">
        <property type="entry name" value="Beta-AFase-like_GH127_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151:SF0">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20736">
        <property type="entry name" value="Glyco_hydro127M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040472415" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle" evidence="2">
        <location>
            <begin position="451"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="669" mass="73538" checksum="6E62470AC8E501E6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGM5</accession>
    <name>A0A9P6EGM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_875912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGM5"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37959" checksum="A7500F243AB9CCAE" modified="2023-09-13" version="1">MVDWLSPTEIAKDAKAFDRFMHALLGVYIWEWVVSIDFDWEYISGRRKFRWPMIFYFLNRYCLLFALVGIAIALNVTEEIDCQALYTFNQCFGNAAIGLASINLSLRTMAVWSRKWYIVFPLVAIILAHWSLLLHGILLKASWVPEVGCVIVETDSKLLAATFIYSMAFDFTVLTLTAYKLVQPNAGNRSRLVGLIFQDGLIYFILAFLSNLVATTFMLLNLNPVMSIIANVPAAIVSTIVACRIVRRLSNFTTHGAEMFGSTQGSTIAFRSNLSKGLHPKVSTKVSNKEGVHVQMETFESPIDKAGYPEYDAAGNVISGEAYDPESQAISGEFKRPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGT0</accession>
    <name>A0A9P6EGT0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cortical protein marker for cell polarity-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_278280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2503993at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902929">
        <property type="term" value="C:plasma membrane of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048266">
        <property type="entry name" value="Rax2-like_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048265">
        <property type="entry name" value="Rax2-like_third"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20842">
        <property type="entry name" value="Rax2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20843">
        <property type="entry name" value="Rax2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040327271" evidence="5">
        <location>
            <begin position="22"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1244"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="1364"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1322"/>
            <end position="1353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1421" mass="146006" checksum="7E0A11B04B01CEB2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHI4</accession>
    <name>A0A9P6EHI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_292133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHI4"/>
    <dbReference type="OrthoDB" id="3038990at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="329" mass="36050" checksum="C0EF725DB0505636" modified="2023-09-13" version="1">MSLYNGPYSWVPGAFVDPTIKSQQSAGLDILIGSLAVLLWDFISTVAEDVRLVASSAYTIQILCYIIMRSTAIMAWFAAIISQTTLQRDCRKLVRVTIAFMVVNKACTSFVFFTRVCAVYSGNRVVAGTFGLLLLGVVAGSAQLLSGNVILGAPIGPTNHCTVLTPKGFLLFPVPMTEGIYDTLVCLAITYKLAEVDIFSKSIPRIPRREVRRVWWPGFLASPRLRSLSARFLRDSQFYFILTACVKIPQIIILLISVPSHHTSVSPIYFALIFPDLVIVNALASRIFRNLKLNKPGLGLLTADAELAINFTDLPVERSTAQSPSRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHW1</accession>
    <name>A0A9P6EHW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Chromodomain-helicase DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_852810</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18659">
        <property type="entry name" value="CD2_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000130">
        <property type="entry name" value="Chromodomain-helicase-DNA-binding protein 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041150">
        <property type="entry name" value="Cdh1_DBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18196">
        <property type="entry name" value="Cdh1_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Chromo" evidence="9">
        <location>
            <begin position="197"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="9">
        <location>
            <begin position="296"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="398"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="695"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="848"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="956"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1226"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="956"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="986"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1235"/>
            <end position="1255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1317" mass="149711" checksum="4DA45E2AF07E3ED4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI09</accession>
    <name>A0A9P6EI09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_905603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI09"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="91"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="456" mass="51630" checksum="F62E0FB1B16D1CD8" modified="2023-09-13" version="1">MSSRSWSCSISSKGEKVWKTTLPPDYERSYTFQTLCLPGLPSSAHGGLGWDGSTPISCLVNKSHLDALLAALPPTFCVIPQALSPIREEDQLHEVRKTKIKGEGLFATRSIEEGQLILWEHPAIILPSTDREFNKEIYEDLGKAVASASDKELNTRWLRRQAEATKMANEYEGDGGCDTWIEGVVRTNAIVLDLIEGPKMQQSKKKPPQHDKDGQKEIYGGIYPLINRANHSCAPNASVKWDRSTLSASLYALRDIEEGEEIFKTYVNPLLPRAIRLKTLNKNYKFLCDCAHCNLEGKLAVSSNEVALVAESDANRELLATWIFTQPTYKKWSTDLCRADNLFIKSHMDALALIEKEGVYALQAIFIEELAMAHAMLGDLEGFKKWGERVRKLNRVEDPELSRRFQDWLVYPEKRVRRWGWRKRMKEESNGRNAKGIGDVDIGLIFEPIDSESEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EK31</accession>
    <name>A0A9P6EK31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_850827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EK31"/>
    <dbReference type="OrthoDB" id="2354757at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035838">
        <property type="term" value="C:growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF3">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9530384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="34447" checksum="A3C363FB1E496EB0" modified="2023-09-13" version="1">MIRARSSQLTHNSGSAILTGIATVLLLFICISTPVVNSMRMYRISNVINGAIRYVDVGLWGYCVKPLQFGFNSFTFDATVVEGCSRASIGFSLDENVANALKIPEIKGLYSKSFTAILIVFPIATIMTAFSCVLQLTIHLLSKTRGMQLGISSRGVRGIFFFNVLTMFIVFFAFIIQIAVLVTGRARVAYLSLHTSNYRLQFHGENTPWLSGFALLCHFIDLFIINTWRKERLHLEQQKDTEKGAKKAKNMAKNPKQNKGKKAQSALLDAEPVSKSEGDIVEEKKEDAISLPEYKLDGYVIEAADSTKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKE8</accession>
    <name>A0A9P6EKE8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_851013</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKE8"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUSP" evidence="10">
        <location>
            <begin position="78"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="379"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1090"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1157"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1186"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1129"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1157"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1206"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1261"/>
            <end position="1280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1280" mass="143077" checksum="5A692E5756681DF4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKK3</accession>
    <name>A0A9P6EKK3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_904850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKK3"/>
    <dbReference type="OrthoDB" id="5584845at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040185327" evidence="1">
        <location>
            <begin position="18"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="133" mass="13800" checksum="EA724CF3AB382089" modified="2023-09-13" version="1">MLSKLIAFTSLVALAQALTVDVTSELTKRDAKCYAGPGGYGHSNDLDACIQNMVNNPNWGQWDCGGRSFFLGGSAWNSPGDCIGGCKPCLNGSAGLGLEWAKCDQQTGVSAHCWVGYCPPGQSPCGNSDGSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL82</accession>
    <name>A0A9P6EL82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome subunit RPN7-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_849514</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL82"/>
    <dbReference type="OrthoDB" id="422427at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="265"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="491" mass="54753" checksum="6353ACB8836B2BA6" modified="2023-09-13" version="1">MDIDRVEDNLPGSSSFAAPKRIIAPVDEAHPFDLDSYISNYSGRTAIDRLIHIVLTCPTIAPEAFQLCVQHIHQSRDPAMYQNLLQVYEQAASYAEGGSFPNPMELAELDTKWADEAIMKNQADRAKLEVELKTYSNNMIKESIRMAHRDLADFYRATGDYGTALKHYTKSREFCTTSQHVLEMCMSILELLIEQRNYSHLTTYVFKAEAALDATAAAASNAAANNSAGGAAVPATSTKKKPSERESVQAKLDLATALSHLGQSNYEKAANAFLKIGSTKELGDWVGKLVAPGDIAIYGTLCALASLKRSQIKTRILENSVFGVYIEQEPYVRELIESYMSSNFKNVLELLAKYSTRHYVDIHLSTHVNELANSIRNWAVVLYFQPFASIKLERMSIAFGWTIEEVEHHVVNLIQSGAIQGRVDSQNKILLAKKTDYRAELFARAIKAGAEIESTNRKLLLRMKLQQAELIVKPPKGSNHPASLMDVYQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EL99</accession>
    <name>A0A9P6EL99_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_787505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EL99"/>
    <dbReference type="OrthoDB" id="94039at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="41"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="358" mass="40698" checksum="04F448DBF32D2347" modified="2023-09-13" version="1">MQTTSYIIPPSDDYPFYITANRYYTLQWEERSQTDSSALTLIILHSTSFHKEIWEPTLTDFIRLTTKAEDTSISEDQSYKRCRTVNVRDIWAIECPNHGASAQLNLRVKSEPDSGNFSCSKYAEAVHRFLSVPPHHPDGPKVDFRKRTLVGVGHSLGANAILLLQSIKPYFDFSFLVIVEPLVTALGLEHLEPLRERLIRRAQKRDLVWESREKATLALSRSAKWDPRVVDVFVQHGLYEEPKLNGYTLYCSPKQEIAMYEDIDGPTKPVEVIQNICHRTPIHLLLGEYADFVPAHLHQALIDPSSGRHFASVTTMKNSGHLIPQQKPTELAKWLLDVLLKQTAQSTAPPAGSPRHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELP9</accession>
    <name>A0A9P6ELP9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cyclin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_848297</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELP9"/>
    <dbReference type="OrthoDB" id="340962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="78"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="311"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9532073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="39146" checksum="B8F6575093BBB53D" modified="2023-09-13" version="1">MTSPAAPSEPKISIYQGSTQFRNWRYSAEQLAQTRQTLNEVAIAAIRKTFETDESGSSQGVAFLTADEEVLLVKLYISKITQLCGLFRFPEEVEATAVTYLKRFYLKNTVMDWHPKNVMLTALFLATKTTNNPISLEIYTTHIPKTSPSDVLDLEFLVAQSLNFEFAIWHAHRALWGLWLDIQNLSSYTERLDTEIYDAALNHVRASRLTDVELRFSPSQIALASLSLIQPELASQWMESKLTSPSEVEGLAKTVEVIKSIVVSQGLPPSVESVREVDRRLRLCKNPEKVPGTKAFLARKMDDDRLAAEKRSKKVADIQRTENGDPFGNELGQKRGLVDYDDDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELT8</accession>
    <name>A0A9P6ELT8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_849916</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELT8"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000021">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000005">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000001">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000395">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="13">
        <location>
            <begin position="264"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="887"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="914"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="930"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="947"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9530949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="959" mass="105023" checksum="85F333016F0E49FE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELW3</accession>
    <name>A0A9P6ELW3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELW3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="52235" checksum="C610AF0871A3A68F" modified="2023-09-13" version="1">MVKPDYEPGQSFLLDQYPFELVAAVLGQAAQVNHENAERKPRFIASPLILRQVCRSWKAFVDSTPSLWQALVISFPRMETDIVTGVKKWSNRVGTLPIDVYIDGSNLRQTLAWFKKFEAIGDSLAILHPKWRLLELLNVKNFFVNLIQSRLRRAFGGLTIFPILEVVAIHISPNEFSHPTALDFRSLDKLKCLDIRGQKNNFNAHAIPQTQAAQLTNFRLERTSFDFEALGLFVNLRVLHFSPFDAPPARPFGLMSKVLLEQLESLTFVATSWNLTLSIFQRLCLPKLLNLSIALHSSPEPDSDSDTQTIPEVQPLFEEELHSILASFRQVTQLGLVVKTKELTIGRPFFEGLGLLKGPVRLPKLRLFSYEGNLQLESVFCLQSILERCSCRSPPPTTPNSSGSGSYSPDVAALKFVKIKSNDLRPFLLPNNFSRGTEAYATIKEMVVQNTLWLIDDEDKALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMN2</accession>
    <name>A0A9P6EMN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-rRNA-processing protein IPI3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_760839</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the WD repeat IPI3/WDR18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMN2"/>
    <dbReference type="OrthoDB" id="756370at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 4 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="125"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="509" mass="55928" checksum="0FFF057446CC07AC" modified="2023-09-13" version="1">MHLQETVLCATSPTSSAAGPGLIAIHDIQTGATLASFKQTSAGSHSVALLESRNSQGGFIIASQPDKSILNVYNFQKDQISLKIVLPEKLTCIALDRRGDLCAGGTAAGRIFIWETASGIMYKSWDAHYRQVNVLRFTNDGAALLSGSDDSGVNVWSVSRLLDDETQQEHMVPYCSLADHTLPVTDILCGIGLFPECRILTSSVDHSLWDLSSRSVLTTFQFPQAISCLAWDVTERLFFAASSDGSIHQMNLFRERESKIGLVTEAVGGGGVSDVIRVESEVARETRKKRLIVVGQQVKCMAISLSSSSLVVGTVEGLVQIYDIPSHQLIRTISTHKGVPISHVQTMIKPPDLIGHISLEIQIGSDTKDVIPVKPIVPFQRTRDVKSREAHEIAVMLPYYKKISKRDTLDYGLDEMLRDHSFFIQPLEDTLNGSGHVDPLSLKLRVSELESEVERLKEQLGKAKGVNDAMWDTVVQKLVGQAEDVDLTGKGVVVNDVEEEQRKRKRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN17</accession>
    <name>A0A9P6EN17_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_785610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN17"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="28008" checksum="BBC8EFEA70A05D88" modified="2023-09-13" version="1">MTFQSHLHISFQDEHVLLPFIRLNSFGGFFLAGLLTFVICLAERVVSVALEKQWEPYFLKLGRRRIAMWRTFMFSAVTFLRLSYMLISMTFNLGLLLIIVITLSAAQFFIELSNLPKPPSLAGMHEAGDYRPLLSHTQERQQHSLDSLKARSRSRSKPDNIFIHPTQSNVARADAVAMQMGLAHNVERVQEYRYGGTEPAWEVGKGKDLARELLSKKDEKQTPPLHQRQHSKDKFYIGASDSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN74</accession>
    <name>A0A9P6EN74_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine nucleoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_760705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nucleoside permease that transports adenosine and guanosine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NUP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN74"/>
    <dbReference type="OrthoDB" id="2331083at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009486">
        <property type="entry name" value="Pur_nuclsid_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38643:SF1">
        <property type="entry name" value="PURINE NUCLEOSIDE PERMEASE C285.05-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06516">
        <property type="entry name" value="NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013171">
        <property type="entry name" value="Pur_nuclsid_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR013171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="373" mass="40239" checksum="6A82E4B2B20EF766" modified="2023-09-13" version="1">MFEPEAEVWYGIPEFDLLALNISLPGLSPRYPHVHCIADGEVCQLTIGESEINAASSVSAVALSSMFDLTTTYWMIAGIAGVNPEIASSCSVTFARFAVQVGLQYEFDMRELPANFTTGYVPLGVTSPDQYPKSIYGTEVFEVNSALRDIAIAYAKTAALNDSADAIAYRANYMKDGIYAAGAASPGVYACDVATSDVYFSGRLLGEAFSNYTRLMTNGTGVYCTTAQEDNATLEALLRAAVSGFVDFSRIIVMRTASDYDRQFPGEQAHFNLFYANQGSFLPAVKNLYLAGIKVVDGILSEWDNKFAKGIPAPNYVGDILASLGGKPDFGPFTSNDNPVVVGRELKYGNGKLNARNHRRERAGIKARVLGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENG0</accession>
    <name>A0A9P6ENG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_847786</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENG0"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="9"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="245"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="806"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="506"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="687"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="833" mass="97113" checksum="EBB3EA7005136A01" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENG9</accession>
    <name>A0A9P6ENG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_847812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENG9"/>
    <dbReference type="OrthoDB" id="3044801at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="89" mass="8929" checksum="6F86B8B1977CB159" modified="2023-09-13" version="1" fragment="single">MSATVTIWNGADCTGSRGPTTNLNAPVCGTLGSGSVKSIQYSGVPNKIEFYVSGGAHDNCSNGSQASRGGGSGCVTAPAGFNWESVRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPC4</accession>
    <name>A0A9P6EPC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_477053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPC4"/>
    <dbReference type="OrthoDB" id="3263748at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="35303" checksum="C4A12BB54FC52953" modified="2023-09-13" version="1">MSVSSDNLSSLARSKLSLSTSRDVSLHKWVLLKNSILSSPSLPNNPAVPTPQPELHPAYRMGDNEEEDEEVLSSSIVDSDAFMFPLVDGSDSYYDADSSSKSSEAQWLDSLLETLGDDEDDEDYRVDSADSPPHHHHLFEDDSIGSLPADDDEFIYSPRVSPMSSSDDLPSQPYYSSPISVPYTVPYPPLVHAYHHCHPFDSSLVSSLSDSLPEAPLPYHDVDDLEDLPVPDAIEDTSDDESDAPTTPSLGRSSSTLSFDPASIPSPLLPPPSSERSRLRHSSPRVYVDSDDTYFYTFEVDPLPFRHDEHNTSYNGYSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPD8</accession>
    <name>A0A9P6EPD8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_832655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPD8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="231" mass="25411" checksum="7591F31AA92A13CE" modified="2023-09-13" version="1">MDGRATNEEVVETVSRIPHLESLSIEGSNVDENLISLMDAAASSNEGPQFLPRIKSLNFSTEKFGAWSWPILLLSTLKNRPGRTLTRFGFGGDQTRADEGLIGKYMLEHMIVAGRGLTVGWRDKAGIDVLERLCRLHGVEFPPNVRLVKQNAHSDFAVTEESGSYTDAAGAPALRLKNNSNKNNLGLQICVESLTSSQSLSAELSIYLLSEISPLSEILSEKHKMKTARIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPL6</accession>
    <name>A0A9P6EPL6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_847020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPL6"/>
    <dbReference type="OrthoDB" id="248779at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1340.10:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="7">
        <location>
            <begin position="5"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="6">
        <location>
            <begin position="134"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="207" mass="24120" checksum="580244F3D8AF28F2" modified="2023-09-13" version="1">MSEVDESAKLWKVNRTIHELVKDRGFLVSDDELQMDLARFRDIYAHNGAVDRNRLNFYTTSRVNPADQIFIFFSEERSVGVKTMRKLLNILEDKKIQRGIIVFPGNMTPSARKVIVAMAAEYRLEEFAEADLLVNITHHTLVPRHEVLTSEEKKILLEKYRLKETQLPRIQMADPVARYYGLRRGQVVKITRPSETSGRYASYRICF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPS0</accession>
    <name>A0A9P6EPS0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock factor binding protein 1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPS0"/>
    <dbReference type="OrthoDB" id="4159489at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="124" mass="13135" checksum="DE746C2F39BAC5E9" modified="2023-09-13" version="1">MSKPASAQPLKVPATPSKSTDNDKDKTPMPSKQSGPSKLGAIAPKDISSPHELTAFVETLLEQLDSKFDDMSSQILERMNQMSTRVDALEMSIQDIINGDISVPTSPSPAPATPGGIRRAESSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQL6</accession>
    <name>A0A9P6EQL6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Septin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_867121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQL6"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="117"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="618" mass="68720" checksum="9B899F86E173BF2F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER92</accession>
    <name>A0A9P6ER92_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER92"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="148" mass="16700" checksum="416D5A77A4AA79CC" modified="2023-09-13" version="1">MSYVYNDEQAPLDCHSPSDDGTLGDSYVSLPPPPSQDGRATVTRSSPQVVKEHTYHNRAHQLVTVYMPTTGSIYWSVEGFNDGMPFSTINSPTGWFDAIHPAPYVRLFFDDRAPRWTARTPEGARQPGTIMAKWVNNDRRWVTRRDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESX5</accession>
    <name>A0A9P6ESX5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_802043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESX5"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="97"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="199" mass="22502" checksum="30F90CE20C2566CE" modified="2023-09-13" version="1">MLRIAAAKAIRPAFTNLFSQTIYRSLNRTTASATYQSVRWNSKVADTSADSAKTTKKVLTPQEAAKKAALEKRDDLQRDWDAKVLSYEEFLPKTQNPSANAYIIDVREPDEVIQGMIPGAVNLPLSVMSGALHLPHQEFKDKFGFEKPRKNQEVVFYCRSGMRSSTAADVAKRNGWDTNKILNYKGSWLEWTAKQNEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET44</accession>
    <name>A0A9P6ET44_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ADP-ribosylation factor family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_843119</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET44"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04151">
        <property type="entry name" value="Arl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000624">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9534900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="20685" checksum="7A4BAAE3BB01AF77" modified="2023-09-13" version="1">MGLSISSLFSSLSSLVRWSKEQDVRILMLGLDSAGKTTILYRLQIGEVVSTIPTIGFNVETVQYKNIKFQVWDLGGQSSIRPYWRCYFPNTAAIIYVIDASDHARLSIARTELLTMLSEEELKGAPLLVFCNKQDVEGAAKPEEISEKLGLAGGEKTRPWSVRGSCATKGEGLEEGLDWLVNAIQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET98</accession>
    <name>A0A9P6ET98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transport protein particle complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_755826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET98"/>
    <dbReference type="OrthoDB" id="10252102at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="178" mass="19717" checksum="37CAAD8032CE4773" modified="2023-09-13" version="1">MSHHLFLLSPSDTPLYSLTHQSSKPVATITSPLASNLPTWSTSAFAGTLTALSGASSTTQHTSGGAVKVGGGQDRHVIQMIANASLDVIEDEMRKQNLMYFKSIDKFNEWTVSAFVTPSNMKFVLLHEGKNDDGIRLFFMEVWELYVKTAMNPFQTAHTAVRSSVFDTRVRNSARKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETK5</accession>
    <name>A0A9P6ETK5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_842607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETK5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="131" mass="14032" checksum="914723744FCBFDE4" modified="2023-09-13" version="1">MFALPLISTHSSLANHYTSQINMPANFMFNNAWVKVSLPDPPITKVTFPDLTEIQNNNIAVQSSSSFMSLKTIGGPNMKYNFTGATSVTAVAPLKTNPCIIRVATGGSIRISVPNPAAPGTYIDYIFSPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU08</accession>
    <name>A0A9P6EU08_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_235255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU08"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040168123" evidence="1">
        <location>
            <begin position="16"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="9393" checksum="77DF7CC02C8D7182" modified="2023-09-13" version="1">MWHLVSLYMSELSWAAMIVIPPDLPRQSELFCILIFFLLVAMSDSWDPLLLLLILADTTFQSVFGSCRITFYLLRKPAYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EU66</accession>
    <name>A0A9P6EU66_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_841950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EU66"/>
    <dbReference type="OrthoDB" id="21557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051078">
        <property type="entry name" value="SGF11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367:SF1">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="140"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9535545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="344" mass="35847" checksum="1F9949862E33D1F2" modified="2023-09-13" version="1">MPPKSEKDDAISQLANRILSAMLDELILDTTLKSHHEVARSKTVCPVCNTRCGAIHTPGSSSSAANESSQFSAKAPSRAATPSSAASNEFTLAKQNANGISTPTGGKDGNLYLECVVCSRQISSNRYAPHLASCMGLGSARRNGARGTAKPKLPSDAGRSASPVSEGGDGSEERPNGKGKSKVKDDGEFAVSGNGKRKRVGSPHISPNKKSKQGKAAASPVSRVKAEPDLAGLPSNSHFSPSASSQSKVPSKLRDSSTASFLEHSSDGSRDSSPETMRTPGSSFSAQSPARSRTNGKALRGRLPVKGTGPPKRPTPPRPQPIHVYHDEIDHANETGSSTDTDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUA4</accession>
    <name>A0A9P6EUA4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex subunit NOP10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Nucleolar protein 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Nucleolar protein family A member 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">snoRNP protein NOP10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_842060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUA4"/>
    <dbReference type="OrthoDB" id="13807at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904874">
        <property type="term" value="P:positive regulation of telomerase RNA localization to Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.300:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="Nop10-like SnoRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9535620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="64" mass="7477" checksum="BBAA796BDE103FC8" modified="2023-09-13" version="1">MHLMYTLDENGSRVYTLKKLSDEGKITKSAHPARFSPDDKFSRHRVTIKKRYNVLLTQLPSQPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EV81</accession>
    <name>A0A9P6EV81_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_753788</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 12"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EV81"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051403">
        <property type="term" value="P:stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07856">
        <property type="entry name" value="STKc_Sty1_Hog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000049">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000050">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038783">
        <property type="entry name" value="MAPK_Sty1/HOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9535724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="367" mass="41599" checksum="7FC9CECF54D3F797" modified="2023-09-13" version="1">MSFVKLSIFGTSFEVTTRYVDLQPVGMGAFGLVCSSKDQLTGASVAIKKIMKPFSTPVLSKRTYRELKLLKHIQHENIISLSDVFISPLEDLYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIETIASENTLRFVQSLPKRERIPFSQKLRTTDPDAIDLLEKMLVFDPRRRIDATQSLGHEYVAPYHDPTDEPVADDKFDWSFNDADLPVDTWKVMMYSEILDFHQVGDNAANGTLSEGPLAGPEQPGIVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI73</accession>
    <name>A0A9P6JI73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157984">
        <property type="protein sequence ID" value="KAF9521840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI73"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17378" checksum="4D95E2BA9353C2FD" modified="2023-09-13" version="1">MVSSPDAYAGLASVLSKQHPDVQAAYQSNEVEADFEGKSETLPDRDEDDQDNETEYEPLPTIMPSSSYAQMSQTVDGASKGVTDGTDREYRSYNTAWSQSYLFTRELSFDLAKAGNTKNDYHCHHERVDATPLTWMENQASVNAAPTPMPRRCGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK44</accession>
    <name>A0A9P6JK44_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF427 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_647795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK44"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310:SF5">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="110" mass="12403" checksum="DC191C79CE2118F5" modified="2023-09-13" version="1">MVRVQLSGRTLAESKDTIIIDGNHYFPPASIDKSLLISSDTSSVCPWKGTASYYNAQIDGKTNIKDVAWYYPHTITDKAKPIENYVAFYKVESIFFLYCDGLTNPFPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKC2</accession>
    <name>A0A9P6JKC2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_871479</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKC2"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="279"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9523818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="342" mass="39400" checksum="EF41EFBAA61F80B8" modified="2023-09-13" version="1">MSRRIRKSVRVKGTYKLSDFIIQRTLGTGSFGRVHLVRSRHNLRFYAIKVLNKERIVKMKQIEHTNNEQQMLSSVQHPFIINLWGVFQDAGSLYMVMDFVPGGELFTLLRRSNRFPDPVAKFYAAEVALALNHLHSEDIVYRDLKPENILLNADGHIKIADFGFAKSCETVTWTLCGTPDYLAPEIILQQRYNKSVDWYALGVLIFEMLSGLPPYHQSEVNHMLLYERITRGPTFIKFPTAFQDNATDLIMKLMEGDASRRYGNMRHGAGDVFAHPWFREVDWDRLSARDIMAPYMPRINGEGDASAFDNYPEDNIDQSYGLPGPDPHGHHFPDFEYTIPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKP6</accession>
    <name>A0A9P6JKP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Threonine dehydratase</fullName>
            <ecNumber evidence="12">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_645404</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="12"/>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKP6"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04906">
        <property type="entry name" value="ACT_ThrD-I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1020.10:FF:000001">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000008">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="13">
        <location>
            <begin position="364"/>
            <end position="439"/>
        </location>
    </feature>
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        <location>
            <begin position="461"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9524045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="542" mass="59828" checksum="936D2B58B196F09B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLB7</accession>
    <name>A0A9P6JLB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157896">
        <property type="protein sequence ID" value="KAF9524585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLB7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="324" mass="36382" checksum="AED9C238CFF8272B" modified="2023-09-13" version="1">MFEAFNQVRLTEPPGSGTTVSFLESLRSVTVRRGFTRRQLRVSWAKVSNGCLLDSLGTRASIFARPPNSRSKLDPRNQVADSWPYDLRDCFTSSSTRPLSVWRSAFAVRSLQNLDVGGVKEWATKAEGQALAAGMVDEVENDGLKTCGTNVHEISSDATWGKQQQIEGIHPRPASSSRIFTGQPVLDPASETRCCDSTQIASNQASTVKWIDTTCHRQNTCWTPSWEHKERRTSTAVLKIAIRISRTNSQFQTRSHLHLRILRTCDCKMGVSNWDEIPNDGGDNDDNASNLENWHYPLSRPKPTQSPSHHWSYLLDLSLSRPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF5</accession>
    <name>A0A9P6JMF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_859173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF5"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="70"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="538" mass="60597" checksum="A549B864F646E20B" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMV0</accession>
    <name>A0A9P6JMV0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_908588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="3216045at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="827"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="919"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1137"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1208"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="551"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="667"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="785"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="827"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="933"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1234"/>
            <end position="1244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1341" mass="142954" checksum="28B437551D7E8F8E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNU0</accession>
    <name>A0A9P6JNU0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_816168</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNU0"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
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        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="3">
        <location>
            <begin position="15"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="101"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="620" mass="70083" checksum="91235E373AA266A8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNW1</accession>
    <name>A0A9P6JNW1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
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                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="52" mass="5958" checksum="607643939664AF92" modified="2023-09-13" version="1" fragment="single">MCILYSARLGAIKWINGQTFETGSSGWLRQEEAVKHRSPLVRVILDLWQALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP96</accession>
    <name>A0A9P6JP96_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fcf2 pre-rRNA processing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_856027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="156"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9527568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="287" mass="32086" checksum="D4F4BE136827899E" modified="2023-09-13" version="1">MDSIDQNIEKMSQHADSSGDSESSSGSDHLRAPKSIDNRNSPRNNKELSLAKDIYHLDTKGSYKEIYVDEEEDVIILQGGPGLHPIPLLNPGKLPLPYINLGKSRWEGPSSIRDPEVERATALMASWSIPAPPIPPPELTKSGKPLTKREKKELRQKTAGPDWFDLPAPSEADLPRMYREVEALRLRNQLDPKRFYKKDEGEGKGIKGLPRYFAIGQILPSTTPFGGTASSDNLTKSDRKRTLVEELVDDAETKRYAKKKYEDLSSARGAKGKNTLRAKQALRAQKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPA3</accession>
    <name>A0A9P6JPA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_791989</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPA3"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040532109" description="Hydrophobin" evidence="7">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9528302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="121" mass="11948" checksum="3A5E12D9F24180CA" modified="2023-09-13" version="1">MQFKLTTLVCLITASFAAATPLVARGGGGGSPPPPPPPPSQCNTGPIQCCNSVQSANSPAALAALALVNVVVQDVTAQIGLTCTPVSVLALAGNSCSSQPVCCENNNFNGVVAIGCSPINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPH4</accession>
    <name>A0A9P6JPH4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heat shock 70 kDa protein 12A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_767302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPH4"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="67453" checksum="E623EECF37DAE5BB" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPM1</accession>
    <name>A0A9P6JPM1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_766511</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPM1"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9528662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="173" mass="19988" checksum="A5D82DDDAC3697A8" modified="2023-09-13" version="1">MCFRVLRQWQTSNDKKIYQEFCRETSIWRQLRHPNVLPLIGVSMEIFPRRYCFVIPWMNNGSVISYLKAHPEQDKCFFIKQIIEGLAYLHQLDPPVAHKDLKGDNILVGPDLTCFITDFGLSSMLDSQRSRTAGRGTQYWMAPELFGLVALNLDPRPRDVYSLGCTISEVGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ75</accession>
    <name>A0A9P6JQ75_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_766860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ75"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF1">
        <property type="entry name" value="CONSERVED FUNGAL PROTEIN (AFU_ORTHOLOGUE AFUA_1G14230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040411725" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25464" checksum="54CAD17ECAF990BA" modified="2023-09-13" version="1">MHRLQTFLSFAFIFSVLVAGTPTYTLPRCQLDQNIIPGLPSTLVNPSTKLGYVAVAIGTQNYTCNSTSSTYVNIGAVAELFDISCLYMTPALSTTFNIIQDVAIKAWEDAPSAALPKQILPTYFNVGQHYYVPNPVTGQGVNPKWDFSSSRHVTTESADGYVVAAKVTSAASPSGKQDIDWVQLKSITGTLATQVFRTDTRHGQPPASCTPGTPDIQVKYASKYCESILLQIPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQD0</accession>
    <name>A0A9P6JQD0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_790568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQD0"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="737" mass="80674" checksum="ABABF941E2019754" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQI9</accession>
    <name>A0A9P6JQI9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_851995</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TrkH potassium transport family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQI9"/>
    <dbReference type="OrthoDB" id="9999863at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140107">
        <property type="term" value="F:high-affinity potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004773">
        <property type="entry name" value="K/Na_transp_Trk1/HKT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015958">
        <property type="entry name" value="Trk1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00934">
        <property type="entry name" value="2a38euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF30">
        <property type="entry name" value="HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002450">
        <property type="entry name" value="K+_transpter_TRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 10" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="733"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="762"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="232"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="840"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="861"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="885"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR002450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="915" mass="103320" checksum="25719BC3DE6F4F40" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQS1</accession>
    <name>A0A9P6JQS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_905922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQS1"/>
    <dbReference type="OrthoDB" id="3057032at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="422" mass="46348" checksum="FE9077426AA2C43A" modified="2023-09-13" version="1">MPLSKSPKGSYKQSHLNPNRQPSSDSLSTGGVQQPSHPPLPSTNQPTNDAMSLPMFPGPPSPNTPYYPENSNLLQASSSTNNIGEAFMDLDDDDDPPPISRPSPQPLVQTGAHVPSPPHLPTSSSPPSKFSSNISSNASTNFHPSFSHPRQPNHPGLPSRSAPSFTTSGTRSRPVSYAPSEEVMLGLGLGSKINEMPFNLDKTHHLILYELPPSPHFQKRNPSKVSSFSGSMRGPMAYAYDPSADMNRPVDEEDRLHDPNARGYHDNSFPWRGVVNVAALVLMLIGMMALFLFYPIYTHYGDADRNERIQQIIDTNGMSKPFSIVHFPNGRYRLHPPPALIFRPTLYSMLPVSAPWILLILFNNSALVSYTTLFAHPIVIRFFAFLNAVDFRSVLSTAVAGDTSRIPPLEPVIDRNTGTPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQW9</accession>
    <name>A0A9P6JQW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL lipase/esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQW9"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040137663" evidence="2">
        <location>
            <begin position="24"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="33315" checksum="B4057B087E17843C" modified="2023-09-13" version="1">MARFSFFFSVVALYCGLNAVVQARPSSSSRSLADKTINYWFSFGDSYTDTGFNPTGPLPNEANPLGNPAFPGKTNTGGPNWVGWVTGTYNTSTLLTYNYAYGGATIDRTLVAPGNPSVRVLTDQVNEFLDGAAKSPKVWTSDNALFSIWIGINDIGGTWNLGGDRNAFNDKLLDAYFALVQKLYDAGARNFLFVNVPPVDRTPMILRNTPAQQATERDIINSYNSKLADRVTAFVSNNNVGHGIYDSHSQFTQILNNPTQYGFKDATSYGSGNNFFWGNDYHPSSKAHQLFGQTVGKDILGGTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JR55</accession>
    <name>A0A9P6JR55_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_264240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JR55"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="195"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="690" mass="77183" checksum="82F88AE409146EE3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRA6</accession>
    <name>A0A9P6JRA6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate dehydrogenase assembly factor 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_852551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRA6"/>
    <dbReference type="OrthoDB" id="201362at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524:SF3">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="13108" checksum="54E572D8186331E6" modified="2023-09-13" version="1">MGFTRISSTILRQTVRPFLSVRHVSINRPAPLPLPQEDQREFEELLRKAQTPLAPSETHEPEIDLAVHPDARTPIKPAFEGDVNPSTGEQGGPKHEPVGQWTAESGGDWSFKGRVSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS54</accession>
    <name>A0A9P6JS54_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS54"/>
    <dbReference type="OrthoDB" id="2742220at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="336" mass="37992" checksum="1D0C130565D6B4A9" modified="2023-09-13" version="1">MVVWNSVSGWYKAGAIYVKLSHALSGIFIWELLTTLGFEWDFLTFKKKFRWPLIFYFLNRYAMLATLCLNLQPSECRMLEAAQTFLGSASIGLANINMTMRTVAIWNKSRYINIFLGVLITVHWVMIAYATNKARYADFELPGECLPSGDIFKWHTILFSYATGFNLVVLILNVYKLLINQNTLSQSPKTLLRGKSRVAHLLFTQGLVYFIVACLANIIAIVFMCMNFNDIMSVMFTFPAQVFSTIVACRSVRELTNHAYQSSDEVNRLNKARMASTSYGRGPTSTGGIGYTLDHRKLSSSSLKDSDDFTQSGGVLVHMETLVQSDAEFLGTRRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS69</accession>
    <name>A0A9P6JS69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_183434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS69"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="390" mass="43851" checksum="FA5D252DE1C0E335" modified="2023-09-13" version="1">MPKTRMLPATRAARTERRSSALRTGRKPTYVARLLATLHGYFKESGMTRSYISDIDLLEKIREEASEIGEELGKRFDSSTQRALALLRRNHYVEYKPQRTTNTDAILRITKDLETILDTVDEALDGFTSLSDFEMHSAKCEYLRVQVQPKSRKLPSCAELDRENRILEDDNRRLVQENRELEEEITEMREEREEETARPTQPSLQRQDTVMIDAPPLESGMTDSMYDESALESSVLQPLIRQPSNAQTPLRPRSFRHAMASYMTPESPPGVARSLCPPATSRGLTRTDSHLFTPPATPEPPHLTTRSSRSHTPAFDGDAFDDDDEGLQDPSMDIDPAPIDLEKLLEVSMAQAQLEFENAELLGQLEKLRATTFCAVGNVTSAGTSSSPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSG9</accession>
    <name>A0A9P6JSG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_850238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSG9"/>
    <dbReference type="OrthoDB" id="3025094at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040243310" evidence="1">
        <location>
            <begin position="27"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9034" checksum="3F496EE89C1F41E3" modified="2023-09-13" version="1">MDSQEGQRLRLLTLLSLYDLLPYSLSNPPDGSAPSTLEEAIGTQAVQRCLDALANQNPQSLPGILAGILRSSSKSNSCCGSTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT32</accession>
    <name>A0A9P6JT32_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_880733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT32"/>
    <dbReference type="OrthoDB" id="2012566at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02603">
        <property type="entry name" value="HAD_sEH-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611">
        <property type="entry name" value="ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611:SF3">
        <property type="entry name" value="FLAVIN MONONUCLEOTIDE HYDROLASE 1, CHLOROPLATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="481" mass="53945" checksum="829DF5EB7A3C174B" modified="2023-09-13" version="1">MTPQLKNASRYTNIIFDLGDVLFTWSASAPRSPVPADIILKILRSFHWMEYEKGNLEEAEVYSLVAKEFSVTSEDVKAAFQAARDSLQANPQMLDVIRQLKEAGLKIYAMSNISAPDWAVLSTKAADEDWELFSRTFTSAAAGERKPNIGFFEKVIEKARIDPSSTIFVDDKLENVLTARSFGMHGIIFRDQSKVIKELKNLCFDPVGRGQEYLVSHKQNFSSVTSNGLTIDENFAQLLILEATGDKNMVDYAKSSSHFNFFKSSTVPSNSRESFPNDMDTTSIGLTVTDHVDLASKLAVMDEMLKYRNSDGIIQVYFDHSRPRIDPVVCVNVLTLFYSNGRGQELFETLNWVEKILVNRAYISGTYYYHGADQFLFFLSRLIQASSYVQQRLGPVFKERIVERFGIEADSLSLAGRIIAAAAVNIEDKRDLETLLSMQSEDGSWGDGWFYRYASSGILIKNDGVSTALALKAIQLVNSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU00</accession>
    <name>A0A9P6JU00_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_846655</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU00"/>
    <dbReference type="OrthoDB" id="10249309at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="262"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="274"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9532951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="337" mass="36413" checksum="0D1F6676D7399986" modified="2023-09-13" version="1">MFDIKSAFQAILKDEQISPPLAAILALTELIDNSDAGTMFELVKALNDGAEALKNQTTNTISLNAGCELFIAFVTLFPHDSDNFTDLKKELIRHGQNYAAEALTYRQKIAELAVGFIKDGSVILTHSYSRVVMQTLLLAHKRKRISVFVTEARPRGLGIKTAEALTAAGVPSTVILDSAVAYVMDKVDFVLVGSEAVVESGGLVNAVGSNQIAIIARAANKPFYALAESYKFHRLFPLSQYDLPSHTSKILSFPRPLLSEPSLRTNAPDGGLSYPSSGSTSTNQPDLESPRITQESISQNNPNVDYTRPDLISLVFSDVGSLTPEGVSQYLVGMFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU61</accession>
    <name>A0A9P6JU61_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_625652</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU61"/>
    <dbReference type="OrthoDB" id="3228837at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="685" mass="78182" checksum="2E7E532BBB6C2786" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUZ5</accession>
    <name>A0A9P6JUZ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUZ5"/>
    <dbReference type="OrthoDB" id="3270840at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="614" mass="66496" checksum="821CD5496E9F4735" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV35</accession>
    <name>A0A9P6JV35_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_803400</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV35"/>
    <dbReference type="OrthoDB" id="5632at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032954">
        <property type="term" value="P:regulation of cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14499">
        <property type="entry name" value="CDC14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000038">
        <property type="entry name" value="Tyrosine-protein phosphatase CDC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044506">
        <property type="entry name" value="CDC14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="15">
        <location>
            <begin position="242"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="16">
        <location>
            <begin position="311"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="482"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="636"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9534992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="664" mass="73434" checksum="5C96D7B2740783E4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV38</accession>
    <name>A0A9P6JV38_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_845301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV38"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040448226" evidence="3">
        <location>
            <begin position="23"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="238" mass="24365" checksum="5C79F317F316B31B" modified="2023-09-13" version="1">MFASLRLLVVSLAALSLPTALAGHGVSKRSHSELAKRQNDNSTLSKRATGARATYYDVQTGNQVMCGGFRNNGESIVAMALGRMQSDPSLCGKGINIHYGGKTVYATVVDGCEICPWDGLDLTIGLFGQIADMGAGVIAVDWEFAGAAPPPPPPPPPPPPPPPPPPPPKPTPTPTPTPTPTPKPSSSAPPASSQRPSSSAPQSSGSAASLAPTQTSNVANLYQVFVQYGGLAAAGNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JV71</accession>
    <name>A0A9P6JV71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L6, alpha-beta domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_873069</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JV71"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="99"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="191" mass="21492" checksum="316F931FE78F7B52" modified="2023-09-13" version="1">MRDVLQTEELEIPSNVEITVKSRLITVKGPRGTLTKNVRHVDMDIRIIKGKTTKATLAVWQGGRKHVACLRTIRSLINNMVIGVTKGFRYKMRAVYAHFPINSIIQENGHAVEIRNFLGEKTVRHVNMLEGVEVSESKNQKDELILEGNDIDHVSQSAASIQGSCRVRNKDIRKFLDGIYVSDRGTIVGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVG2</accession>
    <name>A0A9P6JVG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_473124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVG2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="160" mass="17781" checksum="E7D81783F2E3D7D1" modified="2023-09-13" version="1">MQRGSGAYPFGGNILTSMNRVGCPVPCTLLSTVDCRCCIPHPHPRSLFHLLPLSRLPLPSSVFYLLTSMFTSSSTFTFTFTFTSSCYHTSTFITILNGPAPPLQFAFLTKTYTLPLPYYTSFLAYSLPLLFTLYTQTTNHLLILSCFHDRFALCSSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVM4</accession>
    <name>A0A9P6JVM4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Macrofage activating glycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_888623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVM4"/>
    <dbReference type="OrthoDB" id="2564904at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040118116" evidence="2">
        <location>
            <begin position="26"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="3">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9534646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="404" mass="42597" checksum="10CB991A6F88E4FE" modified="2023-09-13" version="1">MVGGAVAQTPAFKGLLLLEPGLSSAVCLTAASNADGAIVTIQGCNGGDPQKWLFDGGAVKIFGDKCLDVPQGANVDGTALQIWTCDGGDNQKWSYDKWSNMMGWSNKNKCLDLASGSTAPGNRAQIWDCTGNNINQVWKTGYPVNQLPQTSQDGQSGTNNCGTGNSDNSNCQTAWINSASDFCFWAPPTVSPIGDSEAEVVAYCTKSGRGSRLIPDGTLKGVHFVQTPEFVQITGVGDFTKVNVPKGDAGGELDNRGADGKGNPVGGLLYGNSFGQGLQYHEWTSFISETEFCFRACVGPRATQLCNHIYDTMGCYWNMPANYDANVYEECQGDSGEPMGVYGTSTWFQGVNPTPGPHAAPASSNCQSLPTVSVSPLQQRGAVDPVEKRLPSSPFPAATPAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E331</accession>
    <name>A0A9P6E331_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_841121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158013">
        <property type="protein sequence ID" value="KAF9521617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E331"/>
    <dbReference type="OrthoDB" id="3270451at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="912" mass="100861" checksum="F395BBF859D94863" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3C3</accession>
    <name>A0A9P6E3C3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_184615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157994">
        <property type="protein sequence ID" value="KAF9521739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3C3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="12115" checksum="E93FE0EBB6949D24" modified="2023-09-13" version="1">MNDLLALQALRVGARHLDWHQRPVEAWGGLLVSVVMLKQNRLRPPELPLRETFSSLPHSLSPPIALRCTLLGVATTIFPILMLRIFDCTKHTRALVRFERERVVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3H3</accession>
    <name>A0A9P6E3H3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157986">
        <property type="protein sequence ID" value="KAF9521820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3H3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="149" mass="17150" checksum="7E94F8704951F416" modified="2023-09-13" version="1">MSLSDENNLAHFLHRYRHHCGYCAAQGEDHEPHEITKCSRLFNKPIFFQWKRGLIYPHGTSLRACWFCHIPTTTSLHPQFSVVGMCPLKDVVVPMMYAILTNDVLRERAQARFPQMPSLPNATNWLVQDSGNGFSNMVMACMWFGDNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3H5</accession>
    <name>A0A9P6E3H5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_740682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157983">
        <property type="protein sequence ID" value="KAF9521841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3H5"/>
    <dbReference type="OrthoDB" id="3070505at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23342" checksum="9927413C842FFC1A" modified="2023-09-13" version="1" fragment="single">ILNHNVAKDLLLVGTLLDCCSSNYDVLFIQEPLWGVIRSVPSTTDKSRDDVIGSLIHPRWIHMVRPPDFHAPGHCPRVMAYVLKRLEHMRPSMRRDIVDYHNMLLLSLFEKGGKSYNLLNVYSDDRRTAINYLDEHSIDFPNLCYMGGDFNPIEWDPEVSALGGAAAKLEEFAASVGLEYTPPSNPGPTFYPHNPELRSSVLDLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3K3</accession>
    <name>A0A9P6E3K3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_801121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157977">
        <property type="protein sequence ID" value="KAF9521886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3K3"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="3">
        <location>
            <begin position="46"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9521886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="58732" checksum="F1883BFC23C0FE74" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3T6</accession>
    <name>A0A9P6E3T6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3T6"/>
    <dbReference type="OrthoDB" id="3121373at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="30403" checksum="3DA15D520B5DE019" modified="2023-09-13" version="1">MQSKPAKTATPTVSPAAFGYLVVGRPMEAKFQSLGQHFNISYLPYHLSENAEQTLMGRHICLWLAKDVGDIEVVAYIIWPGTGILSLGEGLNANHPSRLVELGRDSGTFQSDGSSANIIMQELLNLATRPCILFVRSPPMQEDFLEEEARRLSFCAKAVNWTSELEAFLDAAALSGDAVKSSQIHHWYQKTITTLQTADQTAFLFDPTRFLAGMLKHLHHTLLNVNRLDVNQKSRTGGPVLIPMCFVRSWKEEVISMVQKDFTVIQHMMTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3V5</accession>
    <name>A0A9P6E3V5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_865014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3V5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="280" mass="32024" checksum="92163E85ADD4257D" modified="2023-09-13" version="1">MPVDRSKKKVADKAGHLSIPPNANWSIDDVPIFLKFLKQVKSSEEIPALREEFLKAHPKCDSCAHQVKCKPNPTENFSVRCERCVGRHQVCPRQTAFCIYYIFRHMEKPMEEIQEMYDVYGDIVRGKFKAETQRKPQGSTIRVSRKVPERHIEYIVISDDDNSDKNGQTSRSKGKEKVKEEIKEQDDVTMAEVGEKASTPEVENANEKVDIEKLLLLTALFAMLRDRIRSKVRKFKADKEVDTLEALLSEIEQLDGIGQGFSDALGDVETNNLEFSKILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4V5</accession>
    <name>A0A9P6E4V5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_871961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4V5"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="128"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="283"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="36965" checksum="A5581A6A14599A3A" modified="2023-09-13" version="1">MRHPTLSYSTGNSLYVYNEARKWFPIIFSIANPIMFLFNAPFGRFTLKNQSSIFLVDGRIAWTIMELPSPCFFLYNFFTAPLAVAAPPVPFTLASLTKPYNILALCFVMHYVNRAIVSPLRTPSRSKSHIIVPFAAIIFNTLNGSLMGAYLSSPFARIYLSETRPAFFVGLGMYVLGLAGNIYHDEILFNLRRKANTKGKANENDAKAGEHYAIPQGGLYALISYPNYFTEWIEWWGFAMAAAPPPFYLSTLTVSSLLKVVNPMTLFSILTTPAHRWAPTFSPPWVFLFVEVAVMFPRAIRGHQWYHNKFPDSYPKERKAVIPFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E579</accession>
    <name>A0A9P6E579_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157935">
        <property type="protein sequence ID" value="KAF9522747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E579"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="14639" checksum="C6028D7EB9E8C518" modified="2023-09-13" version="1">MAISMFSSIFCVQFSLDWAETTVYAILDDTVRAGPIPHPRRWLPYYRRPAQIVFSGSVIGLIACSRTLTVTPTTTEYEPGLRSASESQEGADFGADNSVQLFEAFGGLANEEAAEVDAPSAPLGDFQAQSAGNARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5E8</accession>
    <name>A0A9P6E5E8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_863856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157931">
        <property type="protein sequence ID" value="KAF9522896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5E8"/>
    <dbReference type="OrthoDB" id="4138492at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41814:SF1">
        <property type="entry name" value="CELLULASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41814">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040420382" evidence="2">
        <location>
            <begin position="20"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="432" mass="46572" checksum="FDEB5DC3D9E63955" modified="2023-09-13" version="1">MRRSITLILLGTLTRYIRAQDLTDAQIGTINSRLSDSAKTSWELGTRTQTLIELNAQTYSVFSDQSLPPPSSPSGGDASGLQAVFGIAKSVVSNRVKTSGPAPLVEDGSAADPASIGVAVLIANLTGQDKGQVDYSGAAKSQIDYLLTSVPKSSDGAISHRAANLQLWSDFVYMVPPFLAYYGVTTKNKSMVAEAYNQVKLYRNHLRDGKKGMWKHIALGTSGNDDGFWSTGNGWAAAGILRVWATMKHSGYSSSFKNEQKDLANWVKEIHSGIYQHLDNTNLFTNYADRPLTSSGNFYDASSTAFLASTVYRAAVLLDQHTYLPQAERSRKALSASNSNSSSSTSSSSLDSYKHFTSEGWLTPVVDPHAFGQQGSQSPEGQAFVVQMHAAWKEWVKDGSKGANAASSARLTVEVQNLVLLVGLIGGPLQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5L0</accession>
    <name>A0A9P6E5L0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_69984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5L0"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="61216" checksum="FD95D654F353B0E9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5U2</accession>
    <name>A0A9P6E5U2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_822192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5U2"/>
    <dbReference type="OrthoDB" id="2997372at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="18371" checksum="5125F2535D5754B9" modified="2023-09-13" version="1" fragment="single">MSAQVTLTSQLQKTGQPEPNENNFTCEEHQLGIWKIFLASQSSTGLIQEITESLPLLIKLLSEIHASNLFLSHIFCHLWAPVQRVVEIYLSSFLLRQIEAAVISREVRSSGLLFALIARCLVVMVSSCMEAWISERTAIQESKIRTILNLQMMKRNLDMDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6H3</accession>
    <name>A0A9P6E6H3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_898803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6H3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="16424" checksum="6AAD9DC51F857BF4" modified="2023-09-13" version="1">MHFREASFIVLTFFTVIFFSPSINGLPVQRYGLSSRHLDPATNSTPSVKKLVIISGLFIFFLALAGVLTLRVLSNDTDASSGQTLFLAPSFNPRRLWGGVCELFARVPEAQQVADVTLEDVAPQAIPAVQRPSRATTRGKITRPVAGIRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6W3</accession>
    <name>A0A9P6E6W3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIP-1 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_821296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157914">
        <property type="protein sequence ID" value="KAF9523602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6W3"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1420">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042042">
        <property type="entry name" value="Tip20p_domB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="821" mass="93484" checksum="2777A163F651BCF4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E751</accession>
    <name>A0A9P6E751_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_886604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E751"/>
    <dbReference type="OrthoDB" id="2970010at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040327606" evidence="1">
        <location>
            <begin position="25"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="142" mass="14557" checksum="B417A7A7C2CE9B32" modified="2023-09-13" version="1">MQFTTSFFAFVATALLALPNQASGAALGDVQELEARQTRTVAFNVAPAGASCGSGTTIFCTTGSGGSCKGNFNPKQASIVVTQAAGNCHVSLYPQNNQAGGVVERLNTDTTGTATVYSATKGRRDQGIRNGQGGISVKYKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E777</accession>
    <name>A0A9P6E777_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_861989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E777"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="424" mass="48106" checksum="A07E9BD01A2975D3" modified="2023-09-13" version="1">MDTLPEEIVELFIKSIDKNGEGRKVMCACMSVSRRFFRPARSRLFSSVEFDRNLNIGLKLKHFRELLEYNSASYPPLGPCIKSLTLDWPSTFSPESVLNENEIKGAILLLLAGPSCNIIKLSVNFGMALFPDPNSDYRAYHAFRTIFSVPSLQSLSLSWVRGFPSEMINIFKIQKLHTVLVQCRNPQTTTISVTPPSTEPKRALNPQLREVVVLNAILPQEWFQDPETSPFSRLESLSMHLGTRMADNPSDLFDKYLTACQHTLKNLKIHLIPNFSAIYPHSLQQMTELRKLTYIARYGYSRSDGENISWAMKPIIQSLATMVDAPLNLQHIVVCIPINLSDHRLGHIIFGEDKKTSELMDTLSSRRLESVEKVEIVLHLYGKQKPVRGTNITHPLPTFAVQAKVEHPRVILTTNQTEEYGEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7C5</accession>
    <name>A0A9P6E7C5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_910220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7C5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="270" mass="30762" checksum="F208CC89840C5CB6" modified="2023-09-13" version="1">MAPTSSNSLSPWLFLTGSLRRPRLLRDGCLIFQRRKDAHLHRLQRISSIENAFPNSPLSKNLRDQGFDEGEESITEKILTEYQMGLESFQPAIPDPIYQRYLPKATSSLKPLRLASIHSQDTASVYSVASAAWYLPEDIVDKQLNERSRYPLPHRMYLAAASSREVDTFQPPKLPTMRRKLDSRPFTVTRKLSNSKRKTNWRRSGEGLKLVARKKLRPLRVVNRGPTPSMESSNSSARPSGVRIQAAHGATKHNWKRSLSSSWSFPPPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7F1</accession>
    <name>A0A9P6E7F1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_862113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EMC8/EMC9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7F1"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08060">
        <property type="entry name" value="MPN_UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005366">
        <property type="entry name" value="EMC8/9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941:SF10">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03665">
        <property type="entry name" value="UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="2">
        <location>
            <begin position="4"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="203" mass="22540" checksum="9C861DAEC3D9B154" modified="2023-09-13" version="1">MASYEVAPEAYYKIYFHAAKHPHKPVNGVLLGTQNPPRSGVVKIVDSVPLLHHWTSLSPMMEIGLDLAIQHAENERLQVVGYYQACERLDEVVLAPVGERVASKVQEKFEDAIAFVVDGQKLGSSESALVPYLPLPSTNDWRPASDAQQPFTPSSRFQLQSSGSPAEAARLVNEVNQQFAFGDFDDHLEDVTIDWLRNRACLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E888</accession>
    <name>A0A9P6E888_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_861562</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E888"/>
    <dbReference type="OrthoDB" id="338614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01486">
        <property type="entry name" value="Apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.70:FF:000001">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme atg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000243">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006285">
        <property type="entry name" value="Atg7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01381">
        <property type="entry name" value="E1_like_apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="9">
        <location>
            <begin position="337"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606285-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9524295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="689" mass="75672" checksum="9814103682A8B86C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9R3</accession>
    <name>A0A9P6E9R3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SGNH hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_909454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157889">
        <property type="protein sequence ID" value="KAF9525055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9R3"/>
    <dbReference type="OrthoDB" id="2141316at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1110:FF:000010">
        <property type="entry name" value="Putative rhamnogalacturonan acetylesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040106031" evidence="3">
        <location>
            <begin position="16"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9525055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="27712" checksum="D7DDC23E8E383A5B" modified="2023-09-13" version="1">MKLSLSTVLASVALAKPDPTIEKRATPTVYLAGDSTMAEGGGGSGTGTQGWGHYLQYSLSVPVVNNAIGGRSARSFTVEGRFDAIASKLKSGDIVIIEFGHNDGGSLSPTDNGRTDCPGAGTETCTSTYNGQTVTVYTYPFYLIQAAKLFVSKGAKVILSSPTPNNPWEGGSFAYSSSRFTTYTHDSAAAVSVGYVDHGTYTANIFKSQGLNTVNTYYPNDHTHTSPLGADTVAKAFVKGLACAGTANSPLASYIKNATSSIPGSCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9S8</accession>
    <name>A0A9P6E9S8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_860036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9S8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="81" mass="9124" checksum="9F9761379D7A64C9" modified="2023-09-13" version="1">MGVQSSFLSTHSVSTLLLSAISKPRGCHFHLFKLRLGVILLEYVSTGTKIYRSDDHWLFHGFLLTSTYLNSEIPDGIDILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAT4</accession>
    <name>A0A9P6EAT4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7330 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_897055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAT4"/>
    <dbReference type="OrthoDB" id="5289249at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055754">
        <property type="entry name" value="DUF7330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24016">
        <property type="entry name" value="DUF7330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7330" evidence="2">
        <location>
            <begin position="73"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="288" mass="31315" checksum="BB29BF654CCECE31" modified="2023-09-13" version="1">MIIAPEEASTKEQRMQGEVIRVGEADPPPSYADAEGHASSSRSVVPSHPVDSKSQPQRPFSGIPVPQDIKPSNFTYVAQQHHSVKGVWVIDPAMSIPQSFLPPLGPGETEESRKNLALESTNGSIDSDIFILSSNVGAVKGRKRILIHAGSRNGSVAARIHDGPSSPNSSPRLGYNITVKSQNGSITVHLPRTFRGPIRLKTVNGSMKVSEAIRTNWTQFSDMGGVRRSFLGHFDVSEFTPGQEWEGDDLSVEGVNGGIKLVYDDESYLNQQIPKPKSGNLFGRLFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBH3</accession>
    <name>A0A9P6EBH3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_908875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBH3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040392488" evidence="2">
        <location>
            <begin position="21"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16391" checksum="F88E2E958D27AC91" modified="2023-09-13" version="1">MVKFTTSAFVSLLVAVSALAAPLYTSEEIESRSLKLTQEIDVREPGIALKLPRIHIPSGSRHPGRAPGTSRPSGRGRRPRNRNGNPNTARDLAAREPGIALKLPRLHIPSGSRHPRNRTPSPSRPTRGRGRRGTGRNPHAARDLDNLEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBJ5</accession>
    <name>A0A9P6EBJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_509930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBJ5"/>
    <dbReference type="OrthoDB" id="354826at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000354">
        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="284"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9525985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="445" mass="51292" checksum="A7A70A76EE727D6B" modified="2023-09-13" version="1">MGAVCCRAQPIDFDGEVNLFHFVLLRCVGKGAFGKVRVVQHKQTRDLYALKYINKAKCVKMKAVPNIIQERRLLEEIDHPFVVNLRYAFQDDENCFFVLDLMLGGDLRFHLERLGSLSEDCIRFYLAQLSSALSHLHEMGIMHRDLKPDNILLDERGNAHLTDFNIAVHFGERKLTGVAGSMAYMAPEILLKRGYTYCIDWWSLGVCAYELVFGRRPFRGRSNNDLTYSITKDPLKWPEDAENKCSKHGMQVIKGLLERDTTKRFGCKANGEGFQELRRHSWFMNIDWETLESKTQTPPFVPDAKKANFDASYELEELLLEDNPLKARQRKANQDNLSTEMRQMEDQFSPYDFKKMQRRSYYPHNQQLISTATATSSGLASSRPGTPANDLRVENSGLRVEGEMMDPSLMYKNGNSLDLRGSDDIMMKERDTMRVDQLQMDKEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC73</accession>
    <name>A0A9P6EC73_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC73"/>
    <dbReference type="OrthoDB" id="3222669at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="729" mass="79699" checksum="B6932D7DC6CA1526" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDI0</accession>
    <name>A0A9P6EDI0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_447846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157867">
        <property type="protein sequence ID" value="KAF9526809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDI0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="91" mass="10294" checksum="245120532D2FE464" modified="2023-09-13" version="1">MASKYFIKLRFATLRLLCLAYLSSIVLYAEAISLKPSPSWVIFRLTISSIAFVYHLASAFGPTYSLPRVLDLVLTLTELASTVYREILVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDK6</accession>
    <name>A0A9P6EDK6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_769166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDK6"/>
    <dbReference type="OrthoDB" id="3353107at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="2"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="229" mass="26379" checksum="DC4321180D5A8940" modified="2023-09-13" version="1">MIEFRGAGRGSYIFGMSIHNTQIERLWFDVTRGFGQIWKNFFIDLEIYHGLNPRNPVHIWLLHHLFLQSIRADAALWVEAWNSHTMQLPRGQTNASPREMFVFSMVENGPRGFSVDELQDDEEAAGYGVDWEALNDNPLMAHFQEQNPAEPPPPELNDLQPFTPNVPHRMSEVLCEAPNCPLTDELVRELDRVLAERVDLFSTQMGVRRLVWQEAFSLCSHFYGTLNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDW2</accession>
    <name>A0A9P6EDW2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminoadipate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_936123</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDW2"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Thioester reductase (TE)" evidence="5">
        <location>
            <begin position="728"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9527250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1116" mass="123318" checksum="B2C5869BBCDB7D6F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE93</accession>
    <name>A0A9P6EE93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_424604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157863">
        <property type="protein sequence ID" value="KAF9527184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE93"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="10108" checksum="BA440A31B2E86CB5" modified="2023-09-13" version="1">MFLSRFRALRRPTTTLRNARSYAVASPLKAGVSAKFDAFRSLEEENARLLRVVEKRVGERLKLKSEVRILHEIVRMLGLKRSLLDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEE5</accession>
    <name>A0A9P6EEE5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Haemolytic enterotoxin (HBL)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_387606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEE5"/>
    <dbReference type="OrthoDB" id="3046926at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58100">
        <property type="entry name" value="Bacterial hemolysins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040242029" description="Haemolytic enterotoxin (HBL)" evidence="2">
        <location>
            <begin position="26"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="47956" checksum="586F26FD4209D909" modified="2023-09-13" version="1">MPCRTCLYSLLIMGTTTSSLDPAFASTTLPVQEVKEKEPDIQDAPFEGSEMQSISSHYWKGLIAEEVRALGTKIADVEELFASIEATIKKLEEIGVFETYNAQDEKSTPFSRRWQELHDKYTIVTAESRNSVVALDSKIDDFIETVIPILQSTQYNNAQKKNALADCLAYMKEFRPQGNDTSLIFLRLRQEIEQFRKDITIVINTLSQPQATWGDALKKAMKKITDIEAQVNWIPSKTSNKILDRVGAVMDKLEKVASVVAHRKEAIGVGVVSLGVIAGTAYHGLWAVMFIKLGVSAIFSAGAFGALCTIAPFAAGAIVLGLVGDSIYTGWKELEAEDENVKTAIAELESLKADLDLDFNSLGQSLQMIHTAWQGIVDDAQKLVNKFEAFDRSTDPLVLETRINQFKTVYEALQVALKAYIDMFSTSTPTVTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEH8</accession>
    <name>A0A9P6EEH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metallopeptidase MepB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_855984</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEH8"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000006">
        <property type="entry name" value="Thimet oligopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="10">
        <location>
            <begin position="323"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9527549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="778" mass="88523" checksum="FB255F372E75F344" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEJ0</accession>
    <name>A0A9P6EEJ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_836411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEJ0"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="426" mass="44749" checksum="867EFC6E5CC7657D" modified="2023-09-13" version="1">MSFYSSTAYKPQIRQEGFTPMNSNGGGGGSPDGGPSADLFNINSHFLDGPVSRKQTTSSSSSNMDFTDELASFIGTAATEKNGHGHHHQQHQQHLQQHNPYAQDDRPYNIFDTSAPPGASAALNGGAAGTNGNQPGAHPSSVSSTTSGFSVHSEYHPHQHPPPPFNSTLPALNSSMRYEPHPDPPYNPRHTPSPIHSQAGVHSPILPPPPPPHVANAAAHHHHQQHQQHHPHTHTQNHINSRSRSRSRPPTSSSSNEGGSAANGVTVNPAGVTVNSAAGGIGPARTTRTRRNNSVSSTSPPPYGRPHAIVIPGSRGAGSGNGNWFVSSQSSFLLLALGTPPPRLFSPLPISNLPFLTSSPTSSHLLSPSASHKEFPHPYPASANLPFLPFLPFFHSSPCPASVLLPPSPPASVTPGSAVSFSINSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EES3</accession>
    <name>A0A9P6EES3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CPSF A subunit region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_855877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="120"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="583"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="1066"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1424" mass="157060" checksum="05483361E7F72394" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF39</accession>
    <name>A0A9P6EF39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_907358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF39"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="66357" checksum="B622E0BB5B04CD3F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFU7</accession>
    <name>A0A9P6EFU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_767434</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFU7"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9527979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="528" mass="60152" checksum="4592EA573B79C975" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGC4</accession>
    <name>A0A9P6EGC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_346880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGC4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="239" mass="27395" checksum="3B570B588C1ED3EE" modified="2023-09-13" version="1">MYLPQNLHQHQQLEKCIPPVVMRTHKLHINKMGTRNVSWLGLNRCCIDRYKLLRIHAVNNVPPLTHLSTPVCGYPQNYYGYAQVSHMKQEKVYDQPVHQRDEYAQGSAPLHYEVASTRIKLYGGAKNVNITGAQMNVPPKDEIEAFQNGDGITVANTVMKLGYTMQEVAMNPVRPLMNPAAQVYFTRKFTFSVQSHGAVTNFLQHQLPKHDTLLRYRGSRLFLHNRPVSPNKKDTGDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGF6</accession>
    <name>A0A9P6EGF6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGF6"/>
    <dbReference type="OrthoDB" id="64477at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="224" mass="25617" checksum="771DF77C24037F39" modified="2023-09-13" version="1" fragment="single">MSENITPVVTPRLVTLRSRLPSARIFLRSPKKTDSYSLTCRAHDPECTKYLPWIANPKTPITVESNERQIKNWRASSFVKEIFFCIVLLDKTEAKQDPSQDRLATIGETGLAPLDLDKKTAEVGVMLASGAIRGKGYAVEALDMCFAYGFDVLGLGSIYVNTDRDNEPMKGLMEKKFGVEAVWREKQLDWSFATDRKWWDQRQAEKGEQKMIVDDKVEDWFEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHG9</accession>
    <name>A0A9P6EHG9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-thiolate peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HTP6</name>
        <name evidence="10" type="ORF">CPB83DRAFT_853315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHG9"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040504508" evidence="8">
        <location>
            <begin position="18"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="22"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9529147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="25134" checksum="3D96048E149E55D4" modified="2023-09-13" version="1">MVFSAFLLPALVTVVVALPAFEPGTWKPAGPGDSRAPCPLLNTLANHNLINHNGKNISFAHLNETLGNVVGMEAPLRNAILAGPIQKLGDTFDLHDVALHGDFEHDASLVHDDVATGKQYAPVTVNQTKVVIFKSFSANGKVFTAHDIAAARVSIESDYSSLSDNAVSAGVGEPALVTLAFGSKKDESWVIPVESMLTLLGKERLPNGFVTHDFGLEDLGGLTAEITNDMQAIRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHK5</accession>
    <name>A0A9P6EHK5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VanZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_272894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHK5"/>
    <dbReference type="OrthoDB" id="63581at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28416" checksum="CA4B3F011EA52780" modified="2023-09-13" version="1">MASKTLRRWSSKISKKLMKSYKVKIPKYNLPVRVRPWFVLLTSINITVLAILGFTNIHPKLPLPDKVSHSIAFFVATSVFYFIIDVDESARRIWFWRYFSTMLTVFTCHFLGGVLIEIVQAVLPFKQLELGDILANLLGASLGLWVAFNLERYYRHRKEISRLYRPLSATVSEFEEDEEEDEDDERGVQLLPTHANHKGKGASRLTDVWDEREELFGIGEESDDDDEDEASSSQAKPQTPKIVISHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIN3</accession>
    <name>A0A9P6EIN3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ERGIC53, mannose lectin, ER-golgi intermediate compartment</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_852233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIN3"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07308">
        <property type="entry name" value="lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040136056" evidence="7">
        <location>
            <begin position="29"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="8">
        <location>
            <begin position="43"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9529806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="370" mass="41001" checksum="4EA7985D6EE7F9B7" modified="2023-09-13" version="1">MLSRCSRILSLTTLALVVSTLFSGVVVAADEKGKLGNNTIDRTLQLRTHSLYAPYIDQDLQNRWWDFGADSYVNTNKHIRLTRNVPSQMGWLWSRLAITVTNFVIEVEFKVSGDSSHLFGDGLAMWLTSERAEPGPVFGNKDEFTGLGILLDTYANARHSYSFPRIVGVLGDGKTKYNFGNDGDDQAIGACSANFRRTNVVTKLKVTYVKNGFLDVKVQYKAWDQWEDCFYIEKFELPSNPFLGFSAMTGDVSDAHDIIAVTSWSAILSQPDAPLNKHKKSGFFGNSSHADELNPPGTWLGFFFKLFLLAGVIGGGYYGWKEYQRKQRYGGFGGGMGDFGPPTPRGGAYGMRTPGANDGFGNIYGNTKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIU2</accession>
    <name>A0A9P6EIU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_763403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIU2"/>
    <dbReference type="OrthoDB" id="2893272at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="56552" checksum="B988FA69F891B4FC" modified="2023-09-13" version="1">MPHKVPTVKRFRISNDILILILEKLSPSALYQTCKAFERVYALVIEFQHLRYKFKLAVTGMKDGPASYTARPPAMRLQLLTAYERDWPRLKWIDEQKVKTPATSKINVSGTFLCWAANQILELAELPSWRTGKPLSETRHVKFSTSPDAEWVSVDPLQGLVVTSHYMNTANNQATLRLKLRYLWTFERHPNTTAPQYSCQVAQPVVSVSTYICGNRLVSTVEFTGGLTKHLLMDWCTLQATWLEEQDVVLLNPHLLLGVRKVQNKIMLYLYNISNISSVFVEREYELPPIWVNSVLRFARNSIPNTEINTPATLFYSDPSARVLVLTATGSNTIHWMFMSESFFRPTAHADRRSVPWVFWSQFCLIKELPFDLTVGAPQVVGSRVVYLEKDGSKSPSGQDRTRLKIIDFAPYADIQAPSPKAWTHRGQHCPLKVGEYVREFSSNSSTTNGLAIEKISVTEDNMILFLENCGDIKPINILTFGPSPPQKAVRQEAQYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ55</accession>
    <name>A0A9P6EJ55_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_834290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157839">
        <property type="protein sequence ID" value="KAF9530651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ55"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="53712" checksum="CB455496EB1802A9" modified="2023-09-13" version="1">MTEESVPPIGAELTIQQLFQALRWKFKMHENELKYNSSESERIIKPTVYEGMSPKLKESISVIKDAHRFIAELAAFQNNFASINRLPMEVMAKILGHVQEDSTAQLSEFPLDRGARPVQLLSWLKTFTAVCQYWRRITLSNPSFWNTILVNSFIPTNLFFARSSSSPLQIVVTSLPSEQQHKSTIVRFVSLFKSNVERLERLTIIDSSAFKNHSFRYLLRLPFPNVHTFELDCGGDYDYVDPLLPEIYAPKLERLALYHCNELWSTLSLLATSRLTELSLFYCDRIMVRRYSNGIVTSSQTDFSSSYWHHLRSRLLLSFQIGATPPGRCQMERQGWGHTLLARRNWSTHFSSVEHLHIEPDRGNETIQDLLRDLERLQNPMYPNLVNLNIWLRHYRSIESFLNGREKLGSNEALFNLTDIVDETGYATRIRENGSTYAIQLHLDDDGPALFSWDWMLAQSVPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ87</accession>
    <name>A0A9P6EJ87_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">2-(3-amino-3-carboxypropyl)histidine synthase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_811444</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the DPH1/DPH2 family. DPH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ87"/>
    <dbReference type="OrthoDB" id="449241at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010014">
        <property type="entry name" value="DHP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00272">
        <property type="entry name" value="DPH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF2">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00408">
        <property type="entry name" value="Diphthamide_biosynthesis_famil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9530121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="55831" checksum="4286BB49FDC4B854" modified="2023-09-13" version="1">MSEEPTTSFSTSGEDAVTRVIQVELDASANTLSPKEFDDFFEIEKSAEEILKGDYKRIALQFPDELLHASIPIFQQLKRRIGHGRELYVLADTSYGSCCVDEVAASHVDADAMVHYGHACMSQTSRLPVIYVFQKKPLEVGDCVDNLRKVFEEQNMGSSCTHAILRYDVVYAHQAASIRKRLEEALSNITLLYYEMPFKAEPTSTSTKVSSPPSLDANNATIFYVGAESLGLTNLLITNTSSQVISYDPQANTARLESGQTNRLLMRRYAIVQKARDSDVFGILVGTLGVASYLPLIKHIRALLAKKKKKSYTISVGKLNPAKLANFLEIECFVLVACPENSLIDSKEFLRPIVTPYELELALQSQLNWTGRYVLDFGQILAESENLETSPKQQDGPSTFSTGTNEDDADQPVFSLVTGTYRYTKRYGANRIDTEATSGEDSAAVILRNQDNALLKFGMESAAGQFLQQRSYQGLEVRLGADAPSTLEQGRSGIARGYQDDRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJG5</accession>
    <name>A0A9P6EJG5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Other/BUB protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_875206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJG5"/>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.430:FF:000003">
        <property type="entry name" value="Checkpoint serine/threonine-protein kinase BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013212">
        <property type="entry name" value="Mad3/Bub1_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08311">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00777">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51489">
        <property type="entry name" value="BUB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BUB1 N-terminal" evidence="2">
        <location>
            <begin position="66"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="462" mass="50004" checksum="C670ED9634366EF5" modified="2023-09-13" version="1">MASSPLIRDEVSSPIVDCDLLEAAKENVQPLAMGRRVTALSTILATPHAQREAKISSTRNKLRINVELAKDDEDGDPLDAYCQLVYWTVENYPQGHSAESGLMELLEEATRELKDDREGKWRKDIKYLKLWLLYASYVEKPTIIYKFLIANEIGTDHALLYEEHAAVLERDGRRREADGAYSLGIARKAHPLDHLQSRYEDFQKRMMSNMTLPPAQATVPSSRPARQALAMTSSGAATTPAQAPRSTSMRPTPSSSNTRATTTPQSNSRLQIFVDPTGESAQATDLAGASANEWNELDSRKARVKENVPEVRKMVGSTIKQPGKSKRLAAAAAGAAASSSTSKISIFRDPPPGEASPVSSSKSPSSSASKSFAPFVDAPQEDAEKGTQGSLDGSSSPAFTPFRDEDYTTSPVISGPSTSDSTTLQAKKVDLKAAESTSEAEALRRDPLKNYPAGIRGIDSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJI2</accession>
    <name>A0A9P6EJI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJI2"/>
    <dbReference type="OrthoDB" id="3025194at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="397" mass="45127" checksum="725E8FE33799AFB3" modified="2023-09-13" version="1">MQGLLRLMKSPSPAKENNGLKSISNGTTEKKAEVIPSKPKESAVTSDTKVSNADSPKAHKEAAQTQTTSSGGEIPKQSKRPFPENLNLSNLDDTRILQQTDALDIREQLLDRRDREFERRDRELDRRERELERRERELDRREREFEQERTRASTFVNGLPMTAALMTPTASTPPVAAELSARLEREVAELKTQFQKSLADERKRSETREAQLEARIQRSLSESLDKERQTYYNFMQMSDHEVSEMVEDTVGYLMEKDEDIADRVRFQSLLYLSQEKLASEAGINPDAGSGSLSVAWRLLLGPSLVTQDRLNKAQELFQDRKVSSQTTKVLQNKLAMEYVVEYSSHLRKEGSESGEQSFAPGRIARSAYLETAKRQSERSGLNYESLVTLVDYISPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJL5</accession>
    <name>A0A9P6EJL5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_923181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJL5"/>
    <dbReference type="OrthoDB" id="5106486at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="72"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="705" mass="81126" checksum="0ADEE5F285B9E74D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJM7</accession>
    <name>A0A9P6EJM7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CPB83DRAFT_764358</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJM7"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07541">
        <property type="entry name" value="P-type_ATPase_APLT_Neo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000067">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="959"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="985"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1037"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1063"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1091"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1117"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="22">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="21">
        <location>
            <begin position="208"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="23">
        <location>
            <begin position="925"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="654"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="678"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="707"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="790"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="791"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="792"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="872"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="878"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="898"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="901"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="902"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <position position="902"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF9529869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1159" mass="129416" checksum="5D1E7380DA6934AC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKA8</accession>
    <name>A0A9P6EKA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCZ1/INTU/HSP4 first Longin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_851016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKA8"/>
    <dbReference type="OrthoDB" id="240546at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013176">
        <property type="entry name" value="Ccz1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043987">
        <property type="entry name" value="CCZ1/INTU/HSP4_longin_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056:SF0">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19031">
        <property type="entry name" value="Intu_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCZ1/INTU/HSP4 first Longin" evidence="3">
        <location>
            <begin position="25"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9530489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="671" mass="74093" checksum="A798F770ACD6CD75" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKP6</accession>
    <name>A0A9P6EKP6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_153619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKP6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="174" mass="19945" checksum="E0C1EA5A82D593CF" modified="2023-09-13" version="1">MLNRWFSSLTAAPETSSPLRCRVDTGFQWDADAVSERTILENLETLNSLIVNLVTPLVECVADRRYKDFNRSPELTLNALEVLADHATTFGSVEQICAYLIQNDGINNKKRSLLEECILLDRICSLLYEEFFEGDYFFGLFPGDSRVILNSLFGRIAKDRKWVPLYIDSYQMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM93</accession>
    <name>A0A9P6EM93_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-2 type transporter-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_849520</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="597"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="703"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1130"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1164"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1205"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1246"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1274"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1397"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="81"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="795"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9531189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1440" mass="161523" checksum="940CA924E459055F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMB6</accession>
    <name>A0A9P6EMB6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_84793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMB6"/>
    <dbReference type="OrthoDB" id="3237970at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="88" mass="10367" checksum="E47C1E75040E5C28" modified="2023-09-13" version="1">MHATARRLVRVVPRNVLNVAEEQIYHRPRPQIEDIRQPTVIDMLEQKKVEAGAAWPTNIRIERQLTKDVFKDVVPDVRSLLKKMTKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENA3</accession>
    <name>A0A9P6ENA3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_785848</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENA3"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="8">
        <location>
            <begin position="512"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="449"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="497"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="64297" checksum="3C9D2A6E41409C84" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENJ4</accession>
    <name>A0A9P6ENJ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SacI homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_663685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENJ4"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034753">
        <property type="entry name" value="hSac2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022158">
        <property type="entry name" value="Inositol_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF7">
        <property type="entry name" value="SACI DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G15890)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12456">
        <property type="entry name" value="hSac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51791">
        <property type="entry name" value="HSAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="366"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="HSac2" evidence="3">
        <location>
            <begin position="811"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="940"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="942"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1095" mass="120658" checksum="FD9E99C17692D171" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENR1</accession>
    <name>A0A9P6ENR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_49089</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENR1"/>
    <dbReference type="OrthoDB" id="10248446at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000004">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="215"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29371" checksum="F76CAFDC1D03EC1A" modified="2023-09-13" version="1">MSAQISKKRKFVADGVFRAELNEFFMRELAEEGYSGCDVRVTHARTEIIIRATHTQEVLGEKGRRIRELTALVQKRFKFPENSLELYAEKVQYRGLSAIAQCESLRYKLLGGLAVRRACYGVLRFVMESGAKGCEVVVSGKLRAARAKSMKFTDGFMIHSGQPARDFVDYAVRHVLLRQGVLGIKVKIMKGWDPEGQTGPRKPLPDSVTIAEPPIDKVVLEPSSEQREPASIPAAAPAAAEEPYAAAPEAGFQQQEAFTDQQPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENR5</accession>
    <name>A0A9P6ENR5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_847499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENR5"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901991">
        <property type="term" value="P:negative regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000016">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="635"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9532240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="710" mass="80106" checksum="7E62AC0E55B5E261" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP05</accession>
    <name>A0A9P6EP05_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA isopentenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_891108</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP05"/>
    <dbReference type="OrthoDB" id="775260at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF89">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="477"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="477"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="506" mass="58062" checksum="E535DF438B4F1874" modified="2023-09-13" version="1">MSLRPIIAICGTTGVGKSKLAIDLAQHINRRCSNSYWRGAKIINADAMQVYKGLDIITNKVPEAEQKGVPHHLMGFKEPGEQYVVGEWVNDTMKLIDEMHGNCEIPIVVGGTSYWVQHLLFPDRLIPNEVANRPSSPLFREDDDEPSWSVELAESIFALPQELLTIFQHLPEEPPSAKVDPDAAFQLHKLLGFLDPVVSQRWHWKDTRKVLRNLQIIQDTKRRPSDIIHEQSSTTSHVKPRYRTLSFWLFAESSALIPRLDVRVDDMLSQGLLDEVRWMKDLATRKAITDNKMLGINTDYTLGIFQSIGYREFCSYLDAPNEETYQEAVERMKISTRQYAKRQVSWIRNKLIPAVEAANADDVVTPFYLLDASSLGDLWDLNVHKPAANILESVYKICASYIHQQFIQITDFLDGKTLPDPRSLSQIAEEKLKVKKKDVDPLAVLQARKRRICAICTVEDARPIMIEEGPEWEIHQRTKSHRRLASKRLREETQSEHKPRDVETRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP18</accession>
    <name>A0A9P6EP18_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_741999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EP18"/>
    <dbReference type="OrthoDB" id="1607513at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6967" checksum="AED64F92D3DE84AA" modified="2023-09-13" version="1" fragment="single">LDDSDIPHRTRISELITTAFQEEYAAMVKGLQNSLGRVFFKTDTWLRTNLETYMAVTAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPN7</accession>
    <name>A0A9P6EPN7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="3 14">2.7.7.79</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_867489</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="16">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="3 14"/>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPN7"/>
    <dbReference type="OrthoDB" id="62560at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3000:FF:000001">
        <property type="entry name" value="tRNA(His) guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF6">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028980">
        <property type="entry name" value="tRNAHis_guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 14 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="18">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1 C-terminal" evidence="19">
        <location>
            <begin position="138"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="222"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="29"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR028980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9532690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="281" mass="32762" checksum="0FFCD1173EB857C2" modified="2023-09-13" version="1">MANTRYAYVRDFELPDPLLPGVFMLLRLDGHSFHRFSDKHEFIKPNDVRALKLMDHAAKDIMEEYPDIVLAFGESDEYSFLLRKATTLYNRRQSKIVSTLTSYFTSCYVFRWLHYFPDVPLQYPPSFDGRIVLYPTQKHIRDYFAWRQADTHINNLYNTTFWALVQQEGQTTAEAHATLKGTYSKDKHELLFSRFGINYNKLDAQFRKGSVLLNEASPMTIASVPKPSSPMPMEGKKEKKAKSKKAQRQQHQKKAKIEVLHCDIIGNEFWDGRPEILEGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPR9</accession>
    <name>A0A9P6EPR9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPR9"/>
    <dbReference type="OrthoDB" id="3358048at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="21101" checksum="7C45D31D37DA8E51" modified="2023-09-13" version="1">MNQLSQRIPFKGSGEGDEIDPNTILDEQQQEAVISDLRKQNEAFTKKYLLIVQALIGVSSIFQFLVLSGNPLLTIFPTNSDGASLPLPIILIFLTLYIHGNLALLFFSDEIRKTLNWEGAPAPLPIELIYSLAAVPPTLSLFLGKPWQTTAWWSITLIMVFVTQNIRSNIQASNDGIAELEKMKYRAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPS3</accession>
    <name>A0A9P6EPS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_890512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPS3"/>
    <dbReference type="OrthoDB" id="3127318at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="225" mass="26087" checksum="182A2BF40108083C" modified="2023-09-13" version="1">MTQEVLPEQLDFTASFISLLAFCGTFFAAYRYLDPWKEYFRIVELSEQVRKMWTRYESELLLPRENLQAEYFKALKSLETQAGELAELFIPGTINWRFQFKAWAKILHVKTLSRRIHVFKVTLQTVCEQHRRIRESLADEESEATLYQMNEDVFHLAKKLIAPFVLDGSHVLSTTSNFSGRCNSRFTSPATNIAPSRRNTEQSVLGSETNSSTCKLHYVLVSSHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPS6</accession>
    <name>A0A9P6EPS6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPS6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="27928" checksum="CEEAB3891463E530" modified="2023-09-13" version="1">MSANTNIIENVGNAPNVPVTNHGSRIASIHATSKATINCFNGPNSTPLSDDDYAEVLDGIDIENGAQYTINSFNGNAGVGNTNSSTPGTSWSAPIIPVWTGWEYNGLETSGDYHHADNVNRFYSGRSRQNRTSSTFTRCRVVNDTPTSKTRTTASGSSAEAFDSTLSADFISRTVQLAIATSDPRNNVVEESDNNSVVVSELFCKETFVDPDDVARSASPSHKSQKKGRRHRAWWLRKGLQAFEGVKKGFVGLCKLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ07</accession>
    <name>A0A9P6EQ07_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_757093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQ07"/>
    <dbReference type="OrthoDB" id="10005898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF25">
        <property type="entry name" value="MICROBODY (PEROXISOME) PROLIFERATION PROTEIN PEROXIN 11C (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="36025" checksum="4FFC16CD655052E0" modified="2023-09-13" version="1">MSRSSKGLSAARLNDSILGCFSHVQPSETLDHLVRYLGTWSGSDKLFMVIQYALKLIVPFLHLRARLQHRAGLRKTPTSNLAVNYGQLASTLGEARRLWGIWGILPIYQWLISLERRPSESRKILTIERLQGWAMILFFPLEHLSYLASHNILPAGITSPLSLFSSKKRKINLNPGTLSMWSCRLWGAYVLLHFAHLFEDRKLILQRYASMRRANGGTGLSDDNKAEMKQRWDAYWSEVVINLGYLPLTVHWSLEKGLFTNEVWVGVFGLIAAVASFRSGWKATAISPAPSSPPVEQTKENAIVSSPNSPYGYEIGQQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQD1</accession>
    <name>A0A9P6EQD1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_846722</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQD1"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000381">
        <property type="entry name" value="TFIIH basal transcription factor complex helicase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="7"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9532977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="788" mass="89500" checksum="1E0159EAE61B77F8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQE8</accession>
    <name>A0A9P6EQE8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_756217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQE8"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="327" mass="36743" checksum="DF09590CD4A79586" modified="2023-09-13" version="1">MSPAIEKYLTLKDGRTLAYADCGNLSSDKLVIFLHGAFGVGITDEEKIQPSLTEKGVHYVAPTLPGWGKSSIRNHSIPYHLGFTSDIDQLIDHLHPTKNNLRIYLSGGSFGSVPAQLLYGAPFDIFPNGRYVKGCMLLAPFSPFREDKEHGKEMTMSNYLFIGAPSQYLPFHLISRLAKATISRQLGSPEQAEAFVRQNIFNKMDEEEKATFAKWRADTGRKEGELEGDFGRNMHRSVQETWDGFFDMPDITNGDWGFKVTELDAEHCSDKRPVFIIAAEGDKMAPASMAKWLATNYRSARLRMITGGHLSGIYSLNELWKEFLEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERI4</accession>
    <name>A0A9P6ERI4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Histone acetyltransferase type B catalytic subunit</fullName>
            <ecNumber evidence="3 9">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_480592</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 9"/>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERI4"/>
    <dbReference type="OrthoDB" id="10253098at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013523">
        <property type="entry name" value="Hist_AcTrfase_HAT1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21184">
        <property type="entry name" value="HAT1_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038084">
        <property type="entry name" value="HAT-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="14">
        <location>
            <begin position="5"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with histone H4 N-terminus" evidence="11">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with histone H4 N-terminus" evidence="11">
        <location>
            <begin position="231"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="247"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="254"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with histone H4 N-terminus" evidence="12">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9533547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="50526" checksum="BA9525B92296A395" modified="2023-09-13" version="1">MATEWAADANEALTLSLVRSAKDKEALSREENYEGFNPTFTYPIYGEEEKIYGYKDLLIDLRFASGSLAQYLSVSYSEKLPSTSTVDDVEAILQNFIPEGYDTDETTFLQRVEEDANTFRPPGQLIHSYTRAAPNSFSKGKRKRDGGTSQALDPGSNDVIEYEVYHATWDSPGFREYHRRMQLFILLYIEGGSYINADEDTWEFVLLYEKRKRKDDSHAVAYHFIGYSSLYPFYYFPENVRMRLSQFVILTPYQRHAHGSELYKAIYNYILKSPNIAELTVEDPAEAFEDLRDKNDLQLLLSDERFLEEGVGKKPIDGKKRKVVKESSTGDGDNDNDGKLGPPVDRAWREKWRRDLKIAARQFHRLIEMLILLKLEPTDRAKLKAYRLQVKERLYRFNFEVLAQMEQDERYEKLEETFQSVIEDYHRILQLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERZ2</accession>
    <name>A0A9P6ERZ2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hepatocellular carcinoma-associated antigen 59-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_831315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERZ2"/>
    <dbReference type="OrthoDB" id="5627at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="29016" checksum="EEE0200177381777" modified="2023-09-13" version="1">MLNHRMLGDPLRKLRKARGGIDAAKLSKGDVRKKRRRRDEGEQGGLKKGAGHEDEEDEEDQEAKTRRVVRANNFTQQTNALDVDKHMMAYIEENLQTRSRPREDSDEDKAPVDPQEALYNIADKWKFEKQKPTTDVGSVSNSAAMLTAIPEVDLGMDARLKNIEDTEKAKRVKAEERNDRKKANNDEDHLVATRFYRPNLRPKSDADILRDAKLEAMGLPPQEGEPRRTNNDRPQTATDELVMERFKKRMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESU6</accession>
    <name>A0A9P6ESU6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_888227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESU6"/>
    <dbReference type="OrthoDB" id="5564877at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39473">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39473:SF1">
        <property type="entry name" value="DINB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB-like" evidence="1">
        <location>
            <begin position="35"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="22061" checksum="A1C192005A5889A8" modified="2023-09-13" version="1">MTFSESDFAAASRQEVVEQQLSVAKTVLLQAVDLIDNHLTSDDQLTIHSKYMPGSTIGKHLRHARDHYVLLLSCVKKPEAPRAFSYDTRIRNTPMETQRQSAKESILETVAQLEEFIPNVNFDEEISLEAVTPYMHSFKTTIGREVWFASLHCVHHWSMVRVIAGEIGITLSDDFGFAPSTLVFNDKSAPLGKVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ET76</accession>
    <name>A0A9P6ET76_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CPB83DRAFT_780189</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ET76"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13 20" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="17">
        <location>
            <begin position="39"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="213"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="486"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="19">
        <location>
            <begin position="592"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="14">
        <location>
            <begin position="699"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="1072"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9534569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1224" mass="136982" checksum="A3628E3625ECAF16" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETP1</accession>
    <name>A0A9P6ETP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ArfGap-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_755421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030100">
        <property type="term" value="P:regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9534672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="412" mass="43960" checksum="0105D07E6D2F900E" modified="2023-09-13" version="1">MGDQAAAKKILNALSKREDLGNKVCCDCSNPNPQWASLGFAILVCLQCAGTHRGFGVHISFVRSISMDTWQEDQIKRMQLGGNQPFKEFMKSYQPAEQGGYKEGASAHDTYHSWAAAQYREKLDCMVSGKDWSPSAPTAIFQAASRSASPAPSNQGLRKSRANARGLTGRSNSQSPAPSPSGTPNPDQKTANENYFNNLGKLNESRPDHLPPSQGGRYGGFGNTPSPGPGQHPLSSANAPTLTELQDNPVAAISKGWSLFAAAVVGATRVVNESVIQPGVERVSDPDFQAGVKGYLTEAQQKAASVGSTANEWSKHQFGVDVADSVGGAIGAVRERVAGPSHAGYGQVALTSPNGTDNDMYQDDNDLFSEYRDTYSQPSLNATAASLSNTTPSSTKPPATKKNDWDDEWKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUB8</accession>
    <name>A0A9P6EUB8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUB8"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="62"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="510" mass="57518" checksum="802E58C4A1D8A800" modified="2023-09-13" version="1">MQQESPAQVAKTKEAILPQELGLEEGPADIEEALSTAQSELVELEAQRLALLAQCQRIQAVACSIKAFPDSLLSEIFSHFLPSDVSSGHQAAEVCTKWRKVVLRMPLFWTTLILPGCGHRDNPTFDHLWMHICHFAQRANDHPISLTIGKICRPIFDILIHSIFGHVIAHWQAISFPPVRLGQIQQVFSYYETFTDEADHLTSLSFTSTTLEDEDDEYDDDDDNESEIRPYELGLLAELRALRLDFDNLYFIQKRFDPPWPALTSLELHVDITSEEYLDILSGCRSLESLFIAPDDDIEDDSESGDVVQLDHLKQLTINSPNHPSTLLERLSAPNLEELYLNISHPVDDDNPAISTFLDRLNDAGSLRILHCYGWHEVPLGLFDTPALRNLVTLRLVEPFKAFATDPEDAADGSIFDLLAPVDDDGEDRLPLLENLEIIGYPQISEEECESLASLLQSRCFQGKSNEELEEVQAHSLRRVVLQMTPGQSYLGPWEGLSKLRKHGLLVYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUU2</accession>
    <name>A0A9P6EUU2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PXA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_878884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUU2"/>
    <dbReference type="OrthoDB" id="5582218at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PXA" evidence="2">
        <location>
            <begin position="28"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="60302" checksum="2DDB67F06658320F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI51</accession>
    <name>A0A9P6JI51_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_840813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157967">
        <property type="protein sequence ID" value="KAF9522002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI51"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="151" mass="15394" checksum="C6FA737F72FB0E6F" modified="2023-09-13" version="1">MDRSMYLAPNGAGALGYRDDCTALTLKTILSGELALNWDAELGTGGHGVGVKAVVVIVDVGTQEHVGQSVGLAVMNVSEEPVEQAGQAGSAHVKVEVDVGNDTHVQPGHPVVGGIGQVVGLKVEVVVELVMVPDGAGVNAVSTAVSAWRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI60</accession>
    <name>A0A9P6JI60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">chitin deacetylase</fullName>
            <ecNumber evidence="14">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_920310</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="14"/>
    <dbReference type="EMBL" id="MU157964">
        <property type="protein sequence ID" value="KAF9522032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI60"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="16">
        <location>
            <begin position="118"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9522032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="213" mass="23636" checksum="AAFC92DBD477454B" modified="2023-09-13" version="1" fragment="single">VVQTGAWPDRDEVPPTGSSEVAEWMKELDGHDIPSLSVTKDGSCPSDTAAAADAANRDWLVDVRWTLPSYRSVIALVVADTVACPDKNTWGIRFESFDSGLSCSINSNRKILMLRTLLLGRACNEHWDMPVDEYMNDHEISVHTWSHQLTNQQIVAELGWTRKIIKQVLGVTPMTKRLPYGDIGSFRAISLAMGMVPVFWTQTPSGTKFDTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIG6</accession>
    <name>A0A9P6JIG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIG6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="25443" checksum="26D4ABECFAFF8A03" modified="2023-09-13" version="1">MSILYQTAKELDQELEEFQNSSQELVLFSPPHYVPAFVLANYAKFRIEASKAMLGWAFIPFSILGTPDTPRLKSQTWFIRPPPSKIDVYDFWKNDLRRGNGIHSDQTRNALDIVVPEHFIHKSSLCKNPFAWAFLDAKFRQNFSPNTAMILMNGRKRVLALQHLFNQLPTNPYEEAGSDQMDQRPDSRRSRPVQAAGYSKELLSKSEVRLGEYGLSFCKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ45</accession>
    <name>A0A9P6JJ45_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ45"/>
    <dbReference type="OrthoDB" id="2564234at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="10968" checksum="0B503F15155AB03F" modified="2023-09-13" version="1">MPSFTTVVEDSSPLINYSIGWTSGSPSDDSTVLYSQSSFMSTDKQGEQLTFKYQGTSVTLVGAKRSNHGIYHAQIDSTAYPSVSGQNNLNQEALTSFATKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJK7</accession>
    <name>A0A9P6JJK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_692447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJK7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="243" mass="27413" checksum="C298A41BA285A540" modified="2023-09-13" version="1">MTGSGSKSMIANQAEPRSLQVPIRLHTFEIHNFHFSSFSELFNIKRQRGLPAVDLLALEIVNIYNLPRANQILPFLVERGACNTKHLVLRNLNRPAGLCKVLMSIQLEGTLRCIDLCLGGVLLDHVHDLLKEFTALSAPSVENQVEEIHITIRFSSLTRAGEVYGGGDFIGLAALLATRKAWPSLQSVYLRIIHDFHLSPESTATWQRSPEEQLRLFWSARLLRHYHGAHVLFREAIQGLLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJL0</accession>
    <name>A0A9P6JJL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157929">
        <property type="protein sequence ID" value="KAF9522949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJL0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="12126" checksum="965F2EDD15C75B70" modified="2023-09-13" version="1">MNYLTCLMPLVLATILELRPSAHQSSSKLEAVASPFNYWPLGETTDRSDTPLASIFTDSPVHHIDYTSWKSLCSSRYWVLVFGIAKHNLSLRWLLTFCTRYSEDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJL9</accession>
    <name>A0A9P6JJL9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Microtubule binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_863380</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAPRE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJL9"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035372">
        <property type="term" value="P:protein localization to microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1430:FF:000005">
        <property type="entry name" value="Eb1, isoform E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="12">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="EB1 C-terminal" evidence="13">
        <location>
            <begin position="159"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9523143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="248" mass="27754" checksum="E79DA90780F27C6F" modified="2023-09-13" version="1">MTASRTDLLAWLNELLQINYTKVEQCGSGGAYCQILDSIYGDVPMNRVKMNAKHEYEYIANFKVMQNLFKAKKIDKPIPVEKLVKCKMQDNLEFLQWMKRFWDANYGGHVYDPVARRKGAPMEPPATVAPISSSGSTRAALSAGGGLRSGGRTPVGGRAGSAQPEAVQQLQAQVKELSTHLEGLEKERDFYFEKLRDIEILVQQQMEVLEGEGKEDATLKDIQKILYSTEEGFEVPETVAPADEEETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJM6</accession>
    <name>A0A9P6JJM6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_691040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJM6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="216" mass="24195" checksum="DF73BF38CA711E42" modified="2023-09-13" version="1">MCCVSSSPGYFVPRDSFCCVGVVGVVVVILSESSEDTSSTDQLEKGRNLGIFISSTSSSSRPSPSSKLPQPKHRPPRWHKLRCQCRRSISRYRPCQIFESVLDAVFFECVGEVSFHSESLSREVRLLRALRVDEGAKMKMQVEGVPGKLEGTGERRGGERNERIYAIHCAAFLTTDDDLRLTSYGAVGSFSSSSETFASGIRMYDFNFQPCRRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJS2</accession>
    <name>A0A9P6JJS2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CPB83DRAFT_686923</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJS2"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000741">
        <property type="entry name" value="Putative mitochondrial dynamin GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dynamin"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
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        <property type="entry name" value="Dynamin_N"/>
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    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13 17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="20">
        <location>
            <begin position="249"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="19">
        <location>
            <begin position="826"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9523562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="936" mass="104209" checksum="A950063C119E3B43" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJW7</accession>
    <name>A0A9P6JJW7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_775517</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="55"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="15172" checksum="19E999B41B118D6D" modified="2023-09-13" version="1">MLTPIASSFDIPPTPAIPPGLIATQSPPENAVDPFADANSNPFEDAAPPPDQKWKFNPLEIVRRPFVPQLQDELEVKQGDEVRIVQAFDDGWALAELRNAEGSTTQGLIPLDCLRLAGQSLPSFFASKRRSSSSTVNTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKC3</accession>
    <name>A0A9P6JKC3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_839228</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157905">
        <property type="protein sequence ID" value="KAF9524086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKC3"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF5">
        <property type="entry name" value="STI1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="553" mass="62235" checksum="C5FB931B1EE071A8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKW9</accession>
    <name>A0A9P6JKW9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_861674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKW9"/>
    <dbReference type="OrthoDB" id="545169at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="181"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="439" mass="50081" checksum="CBE7BED21976BCC8" modified="2023-09-13" version="1">MSGFFEHLWTTLNNSFSKITSLQATVIGVSCWLLLVKSQRWKKYDAIHKKYGPKWNNGQGKITAAEAQVIIRMSLHNDMAFLMNYALSFALFKTYAIPSISKLLLGTKQLGSKEMVSRRYADTAILISTFFTCPYSGFWDPDVGRENQELGDKSQPAEDPRAMIAVARMNWIHSHYTIPNRDYVYTLSLFILEPARWAERYGWRPLSPLEKHAYFVFWVDLANKMGMQDVPESIGALEDLVEQFESKYMVPAKSNHETAIHTFNELLGAIPKAFGLRKHADSIAICLLEDNVREAMMFPKQSAGHHSFTQNLLKFVSFVQCHLLLPRASTNPRLTVDNRRVPDTDPCPRLHMKKWPMKPWYKPESIGLGYYAMKLQVALGIFSDMPGPHLKSNGYRLEEIGPVELESSGYEEVFNQAAKMQGCPISGPWSLEARRKEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKY4</accession>
    <name>A0A9P6JKY4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_860794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKY4"/>
    <dbReference type="OrthoDB" id="2928561at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="149"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9524732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="729" mass="82433" checksum="5F4F3B17CA800DF7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM48</accession>
    <name>A0A9P6JM48_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_548107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM48"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="150" mass="16931" checksum="C4CEECC48ED0CACA" modified="2023-09-13" version="1">MISWISSQVITALAALVGLIIYSRYYRRPTKALYTPWGLYIDDTGRVIVAGHFDLMHFDAVSARHRLVINRILSKLPSPRTRQTCPVKTSSISGSTSTTTLFYIKPYMPSNPYFTPRFKILPHNSAESDHPEIYTAGFDIEDVLSSGHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM67</accession>
    <name>A0A9P6JM67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_859684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat TRM82 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM67"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106004">
        <property type="term" value="P:tRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03056">
        <property type="entry name" value="TRM82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028884">
        <property type="entry name" value="Trm82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288:SF0">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288">
        <property type="entry name" value="WD40 REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="267"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="610" mass="66709" checksum="40338D53F5665AB4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMU2</accession>
    <name>A0A9P6JMU2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_503496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMU2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="513" mass="57293" checksum="9C7DBBA0C8B65E1D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMV1</accession>
    <name>A0A9P6JMV1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_858500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMV1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="72" mass="8545" checksum="97489ACE6F965C63" modified="2023-09-13" version="1">MFQIKKWKIVDADRQHHLIIENPRAIRRLFNHVISRIFGNLPSMMNVLSESTFQQPEPFVKSSRVPCRLRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMZ9</accession>
    <name>A0A9P6JMZ9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMZ9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040125459" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12519" checksum="E1AE758E06BD74D9" modified="2023-09-13" version="1">MNSCSLYLSVSLAFILESSSGINYTTRRIHATHAISWKTFVRLKLELLVSMWRRKRRLAIREEGAITSSGNMPQSSSLRMTEMERLGALLVCSHLPAEAYRANAVHNPNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN82</accession>
    <name>A0A9P6JN82_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_896067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN82"/>
    <dbReference type="OrthoDB" id="3263285at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="149" mass="17040" checksum="EC299F2239281644" modified="2023-09-13" version="1">MEQAEAQEFLHPLFLRGWRVENVSSEKDEAGTPHLCGQFTLKNASRTRKAMADIIKLMEKEKHDISWSVTLKARPVLSVKMQTHSARRFPVVLGQSDETRANVTLRDVRFATLLENMLAEKAYIHDENPKPPRSASWDVILAKFTSNDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNQ1</accession>
    <name>A0A9P6JNQ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157859">
        <property type="protein sequence ID" value="KAF9527627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNQ1"/>
    <dbReference type="OrthoDB" id="20734at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018828">
        <property type="entry name" value="RRG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133:SF1">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10356">
        <property type="entry name" value="RRG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="242" mass="27042" checksum="153AE33C9E336742" modified="2023-09-13" version="1">MFLSLIRPFSSSSCIFTKRYVSTVHQGVAFERHSLAVLRQAMSMSLKRVGGKEDGGVDLIGWWWLPHNSMEPSTRTLHRRRLRVVGQCKAEKKKMGPNYVRELEGVLYRYMTDPKDRARHISCEETDIRAASALDFEMVALLISQSPFTKSTILRANSSSIPFLLLHLPAQPPETDTNVVSEELGTAWCNSALGGAQGLLEGCMDIRWERNPLGSGGRPAIYWNGSRLPSWLPPVDSELIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP24</accession>
    <name>A0A9P6JP24_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-8 sterol isomerase</fullName>
            <ecNumber evidence="8">5.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Delta-8--delta-7 sterol isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_907773</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ERG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP24"/>
    <dbReference type="OrthoDB" id="347124at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006716">
        <property type="entry name" value="ERG2_sigma1_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10868">
        <property type="entry name" value="SIGMA 1-TYPE OPIOID RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10868:SF1">
        <property type="entry name" value="SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04622">
        <property type="entry name" value="ERG2_Sigma1R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9527373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="196" mass="22081" checksum="837859103B745250" modified="2023-09-13" version="1">MFWQDRWYVFDPLLHELANSAINASPNNAAGMISHILANLTETYTSSVVHLNSDQSEWFFNNAGGAMGAVYMIHASITEYIMIFGTPLGTEGHTGLHTADDYFDILIGEEWAFAPGQLEIERYTPGMVHLMPRGVKKQYKMHEGCWALEYARGWIPLMTPFGLADGLTSTLDFPTIYRMMRITTREVVGNLLLGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP90</accession>
    <name>A0A9P6JP90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_814184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP90"/>
    <dbReference type="OrthoDB" id="3050608at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="261" mass="27760" checksum="2B8492D4D27793A1" modified="2023-09-13" version="1">MEGLMKSLHLNDNRSQQSHDAPTPPPSAAVSPPTHTPKKEGLFGKLDEFSSAISGHKTPTPSQTPPPPTVAHPQVENHSSRSSDNVFDKLSDAITGKKTPPPPTVAQPPPNQHHSSSVFSHLEEAITGKKTPPPAPPAAPHHESVFDKFSEAITGKKTPPPPPKEENLFDKVGNQIFGIGKPAAHEQKPQGFGDKLNAALGGGAKGEMEEGKLDKAIDLFQEHVLKAGPQSNESALEQAKDKQIADAIRNAIGNSARKDHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JST7</accession>
    <name>A0A9P6JST7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JST7"/>
    <dbReference type="OrthoDB" id="45518at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051498">
        <property type="entry name" value="Phosducin-like_chap/apop_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809:SF3">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="144" mass="16660" checksum="44E3947B92C5B5ED" modified="2023-09-13" version="1">MIAQYRKQRITESKTKQRRARFGSVYPIGRDDYTREVTETSKINEDDDEDKNGTGVVCFLYKDGLPRSEIAFKHIRILAQRHPRTKFVSIVGDKCIADLPDSRVPMILAYRKGDIRQQIVAWGADQERRLEGLSIPLSTFKLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSX3</accession>
    <name>A0A9P6JSX3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_84472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSX3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="183" mass="20839" checksum="AC6E32E8A30612AE" modified="2023-09-13" version="1">MSPSLLFAPDVSDPFTALPSAPNHLTPGSQYSSSTREVNRINTWLTQQQYPQQRSVPQMHSSMVSTPLALLVIMHNLTVYHSPNRIIVLRITGLSILLLHRDPPTCPITIIPMVRMHGIYQRARYCFQRRLFCLMLHLPGFLSQGSVTLRSCRKAGLSLIHILPYPNSIRRLMTWVTLVKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT59</accession>
    <name>A0A9P6JT59_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_849596</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT59"/>
    <dbReference type="OrthoDB" id="65716at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000002">
        <property type="entry name" value="Zn cluster transcription factor Rds2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053045">
        <property type="entry name" value="Zinc_cluster_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986:SF7">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9531230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="493" mass="54377" checksum="537226D79F960867" modified="2023-09-13" version="1">MSSFASYADSAQQGAVAAQPSMSTEHNQTPSAANSVNDDAGKKKKTTKRRKVNHACLYCRRSHMTCDEGRPCQRCIKREIGHLCHDERRPKVGDKPPVAPATSPGAVDLSRSYAPVQVYQGQPAQQASAWPMAMPGYMYQPESFGNEFSVLTDFLETLDDGTFFSPPATVAPALVSSNSFPTPNTANSTPSAAPTTAMPNPQLQNNDLSNTSATAVAATTNADVTETMNLTTSSSEGAHTDGILPAATKTEKFLLTAADQESGSRDERLNRVIRSKYEAGLLKPYNYVKGYARLSRWMDRNVSQESKQQILQPLSVLRPKFRAVAQSLRDLDLVFIEEAFERMLLDYDRVFSAMGVPACLWRRTGEIYKANREFTELIGLDGYMMRDGRLCIYELMAEESAVNYWEKYGHVAFDSSQKAVLTSCVLRYKPVLNAGATSPLISKASLAGTGITKKEEEDDTQLEDGYINCCFSFTIRRDKWGIPSMIVGNFIKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTG6</accession>
    <name>A0A9P6JTG6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arginase deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_904027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTG6"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000014">
        <property type="entry name" value="Arginase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF26">
        <property type="entry name" value="GUANIDINO ACID HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040454592" evidence="5">
        <location>
            <begin position="22"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="422" mass="46197" checksum="D116DE9D7D26471F" modified="2023-09-13" version="1">MILSTFLPTLVVLLRVSCVNTHQVPLAESTESKSTPPKPAADFHPTYDGPTWEKKYGSQYDLSYTGPLSFSHLPYERCLDNASLSYDIAILGLPFDTAVTYRSGARFGPFAIRSGSRRQHSQRGYTLSWADNPYTHGERILDCGDVPVNPFDNALAVDQMEVAYSTLLARPATRSNTEPVTRLLAKDGVEHPRIISLGGDHTIVLPILRSLHRVYGPISVIHFDAHLDTWATYPGQTSEQARVTHGTFFYLAKEEGLLAQNNIHAGIRCKMTGIADMVNDETVGFQAITADDLDDIGSGEIINKIKKRIGDSPVYLSLDIDVIGMKSVFVNKFLSFPLIDPGLAPATGTPEPGGWTTRELKRIIRGLAGLNFVGADIVEVAPAYDHADITGIAAADLVHDFLSLFLAKSPPQSRHARVDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTI2</accession>
    <name>A0A9P6JTI2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras guanine nucleotide exchange factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_890282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTI2"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF99">
        <property type="entry name" value="RASGEF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="348"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="535"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="856" mass="97628" checksum="DB615037F14DDEC5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUI1</accession>
    <name>A0A9P6JUI1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_757582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUI1"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040516566" description="RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein" evidence="3">
        <location>
            <begin position="34"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9533461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16524" checksum="CEAF70BE62C84EE7" modified="2023-09-13" version="1">MCTFLLFPCQRCVSFRQANAFLLLTFNCSGACGQWTPPADFVVALNRPQFGQGYPAANCFKTITMNYNGKTATAKIVDECPECPWGALDLSRSLFTYFAPEEVGIIYGSWHLNGPPSQGPLISTGLHHPVLTMPNSNSKAAAPPPKKAPQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVX9</accession>
    <name>A0A9P6JVX9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VPS4-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVX9"/>
    <dbReference type="OrthoDB" id="2158714at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013640">
        <property type="entry name" value="Vfa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218:SF1">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08432">
        <property type="entry name" value="Vfa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="19739" checksum="1E73B5D851824113" modified="2023-09-13" version="1">MSFTNLYYKRTTGTAKACYVCYKPTTTVLATINTVDFLYTCLGHLSDSGFASQIKDEPKATPAVTAEEIARVKAEYEEKQKKKAEKEKEKAKEESKDKESDKEKEKDDKADTKVAQPPIPSVPATPSGQSTPSHERYTLHRDFFSMRQAEHRKRRQTAQAKDLAPRLPAAPNNGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBX5</accession>
    <name>A0A9P6BBX5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_739122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="MU158063">
        <property type="protein sequence ID" value="KAF9521441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBX5"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="6651" checksum="757FBCAA83D77AE0" modified="2023-09-13" version="1" fragment="single">MYNISSQLSKAQNVSEHPFGGLNFIFAGDFAQLPPVNAQSLYSGSVGTSLNSAMSEKGQKDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2U4</accession>
    <name>A0A9P6E2U4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_751286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158094">
        <property type="protein sequence ID" value="KAF9521380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2U4"/>
    <dbReference type="OrthoDB" id="3265433at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="8560" checksum="EADEFC05E1AFE5B0" modified="2023-09-13" version="1" fragment="single">VYRLHWLRARAQRDRWAEELENTEHEMTRTVLFFIHQAAVWKKYRAVAEQNQSGGEVAYCEQQIHMWNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2X6</accession>
    <name>A0A9P6E2X6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158033">
        <property type="protein sequence ID" value="KAF9521530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2X6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="68973" checksum="50B6466A2B417DB6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E371</accession>
    <name>A0A9P6E371_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_865357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158005">
        <property type="protein sequence ID" value="KAF9521668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E371"/>
    <dbReference type="OrthoDB" id="3071370at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="41632" checksum="31B52F314009EFAD" modified="2023-09-13" version="1">MPYTSSITLPLELWESIIDILPLDTYEGQYSLCNCLLVSKGFFLRSRSRLFARADLRPSYGRRLKAFRKLLEFKGNVEGGLAGYPSLIGSVKSVKIVWPYQAFHQLGVESATVVGLVYGDDIVAILLILAENQMVGELELYFLRTTTFAEIQTSSGVHQALRAIIDSPSFEKLSIDSLHDVPFQVFNIWRIKELDISNVTFLEANPEATSLEPCTTLLSKDEPQLRAFIYMLGNPLHSMWLCSPSLFSDLHTLTLNFDFNPSLSEVESNILLNALLVISHTLHTLDFRMDYPETVLETFSPSLNHLNALHQLRFTILAVGEMNADQPSLIFEQTPEDVRTLEAKAGSSHSCPGGYLLVCFSRNQHAVQIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3K2</accession>
    <name>A0A9P6E3K2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_777882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="MU157976">
        <property type="protein sequence ID" value="KAF9521888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3K2"/>
    <dbReference type="OrthoDB" id="3054060at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="167" mass="19133" checksum="FD870809695FBA48" modified="2023-09-13" version="1" fragment="single">AKRIGLLFSAAQIDYNLDPKLVGDIPDISVGDEVFSDVCGLISKYLAVQLSKAKRITFRAKRYTPTVFQIRYLGYKGVLMLHPELDKEKKHLAEFQKSMKKFTTAVDHTFSVVGHLRLYTFGRFNNNVIVLLSSLGITDEVFVFRQPRRRKTDGLMRQSWTASSFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4C7</accession>
    <name>A0A9P6E4C7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_735979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4C7"/>
    <dbReference type="OrthoDB" id="3268424at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="6564" checksum="B6EC891836BCB1CF" modified="2023-09-13" version="1" fragment="single">PASSVDAERAFSNGRLQIGHLQHGMSSQTFKARVALGSWRDTPFFSDQMASEIIAKAISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5T3</accession>
    <name>A0A9P6E5T3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_66835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157926">
        <property type="protein sequence ID" value="KAF9523071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5T3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="32207" checksum="8BFFAEF41E1D06B1" modified="2023-09-13" version="1">MIHRSELNEIESQHCRLKRGIVLAYLTCAYPDTHLDIKFAEYLLEIGQYLPDEIMSTDQNLLFLEESVIIFRKASRFDPASFADPRFRSFKELALHLESLEKREEAHAIWQEATNIDPSLVRSHSSVAYALFKAADILRAISRYEEAAALRIREIDLYHSPNEYSASEADAYLELAADYRSCRRLYDALRSISVAVNQLRELVLIELAIYSHFLADALSSYFQLLVESESSADKEIINPQVVKGVADQYDTLIQCDTSFLPIIGIQSQPLSLSRQAQKLLHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5X4</accession>
    <name>A0A9P6E5X4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5X4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="180" mass="20793" checksum="1B3E5DC9ADC719B6" modified="2023-09-13" version="1">MVDFHLDLVFFLRDGDIIYDEELRLFELRWAFSSIYAPITKGAETYRSFASTTLWTWEEFELISQMATSSRWIAVAQTSLPVVHSTLAAKASPNIGFDPWFELRRQTFPGGLSILRFTSVELKPLPKKAWFEYHGLTYSHTDQSYWDPSQNFDQVQFGDITHQILLLVQSGRKFVGGVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Y0</accession>
    <name>A0A9P6E5Y0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidyl-Lys metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_878109</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Y0"/>
    <dbReference type="OrthoDB" id="412874at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050414">
        <property type="entry name" value="Fungal_M35_metalloproteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016:SF3">
        <property type="entry name" value="NEUTRAL PROTEASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040387152" evidence="8">
        <location>
            <begin position="22"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Lysine-specific metallo-endopeptidase" evidence="9">
        <location>
            <begin position="210"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9523095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="348" mass="36396" checksum="81F1F92CC72CA026" modified="2023-09-13" version="1">MFSKMLHASLLVFASLAVAIAADPSLSLKVSGPAAVDGVDNLKIVTTLTNTGAETVKVLNDPNGPLSKLPTNTFTITDASGTTPAFNGVKAKYVPKVAAAASAFTILAPGQSIDVEHNLSEAYNFTTSGAGTYDIHPNNLFYLVGDDSSIETVHADTASSHSSKVSGKLAVSRSSAVEKRATYKGCSSSQQSSLVSAASAAQSYAASAYSYANSISTGTTRYVTWFGTYTASRHSTIVSHYQKISGNTFSSNTYDCTCTESGTYAYVYPDTFGTIYLCGAFWSAPTTGTDSKGGTLIHESSHFTVNGGTDDYVYGQSAAKSLAKSNPGEAVFNADNHEYFAENNPAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6E8</accession>
    <name>A0A9P6E6E8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_871718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157922">
        <property type="protein sequence ID" value="KAF9523224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6E8"/>
    <dbReference type="OrthoDB" id="3260919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="62539" checksum="8187C3F241B36A13" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7B9</accession>
    <name>A0A9P6E7B9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial NAD transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_862066</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157908">
        <property type="protein sequence ID" value="KAF9523881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7B9"/>
    <dbReference type="OrthoDB" id="10266426at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015215">
        <property type="term" value="F:nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000075">
        <property type="entry name" value="Nicotinamide adenine dinucleotide transporter 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="33"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="157"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="255"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9523881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="358" mass="39544" checksum="30F23EC3D42D4A32" modified="2023-09-13" version="1">MGDASQAKHTPLQQEKEDSQKKSQGRISRPKPKWTANSMIAGAGGGLVASVATCPLDVIKTKLQAQRAVQGQQGYLGVIGTAKDVLYQSGIRGLYRGLGPTILGYLPTWAIYFAVYDGIKTAFGEPPTAFTTSRKSDDGRIYPAAQVKGYQPAIREHPWSLHILSAMIAGATSTAVTNPLWVIKTRFMTQTWDEVRYRHTGDAAVTIWKTEGISAFYRGLLPSLMGISHVAVQFPLYEQLKLLAQDDSDAPLKPQTILLCSAASKMVASITTYPHEVIRTRLQTQKRPLADDMSSDGMLKQHAKRGIIYTTKKLIRKEGWTGLYRGLSVNLLRTVPNSAVTMLTYEMLMRRLSVWRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7Q6</accession>
    <name>A0A9P6E7Q6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_645587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7Q6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="102" mass="11760" checksum="D82E8AF757CB1806" modified="2023-09-13" version="1">MSLKVLSFARVFTSRSVKGRGLWLNCMVSFRVVQSLFLRCDAGVDDFVDVSLFDCLSVLYFAMLYRKNALINIIFCTYHRSTRMTVNAILYMVDRNVRLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7U2</accession>
    <name>A0A9P6E7U2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribosomal protein L23/L15e core domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_638552</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157904">
        <property type="protein sequence ID" value="KAF9524114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7U2"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019985">
        <property type="entry name" value="Ribosomal_uL23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_uL23_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03636">
        <property type="entry name" value="uL23_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="8">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9524114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="158" mass="17722" checksum="899B00285332A3DA" modified="2023-09-13" version="1">MATTKTPKGKAAAKNTSAKETKAKAAKKATLQGAHSTSKRKTRYSVSFHRPKTLRLAREPKYPRKSVPHVPRMDQFRTIVSPLNTESAMKKIEEHNTLVFIVDIKSNKRQIKDAVKKLYDVQAAKVNTLIRPDGKKKAYVRLTADHDALDVANKIGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E999</accession>
    <name>A0A9P6E999_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_946350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E999"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="27717" checksum="DE0A4FCD68E08475" modified="2023-09-13" version="1">MVDWTSPQTTIRDSVILYKLVHVLLGLYTYVFEWTSLQFDLDYLAGRKKFRWPLVSLCSFSLNLVLPGGLSGFPFAFSAGPVNCKTIYILLHFTSYGSLALSSISLALRTIALWGDNRYVKVALISGMIVHFHLVSGYSFRSSLIRGYGCINGPPNRRAELAIFGYTLVFDLVAFILAVYKVIGVTTGNASIPRRGQGHIRYILFSQGISYFAITAVLNLISTIFIILDWNIVMIIIIAIPTEVLTPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAC8</accession>
    <name>A0A9P6EAC8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_909164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="124582at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="218"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1303" mass="145716" checksum="5ED809B0B7899464" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAY7</accession>
    <name>A0A9P6EAY7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_858511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157876">
        <property type="protein sequence ID" value="KAF9526016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAY7"/>
    <dbReference type="OrthoDB" id="3241054at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040434729" evidence="2">
        <location>
            <begin position="22"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="355" mass="32333" checksum="2698854FF629C83F" modified="2023-09-13" version="1">MFSKFLTSTTLALAFLSQVNAHTGISPALGVSGTLQRSDVKRPSTASPCGAGVTVAAAALDSSTAVTAGADGSVTATALNFNGGADGSRKVTAKVDATGQGKTFVAMTVTTNGDAAPTSNGPQTIVAQLPAGTKCTGGATGNKCLVQYVTTAGFGNCVVVQQGAGAAAAGAGAAAAGAGAAAAGAGAAAAGAGAGAAAGGAATGVKKGSGGAVTAGAAAKGANRAAGNKGAAAATASNSTTAASDAGAAAVASNSTTPATGAAAGTSGGAAKTGKKHHHKGEKKAAGANAGAAGANAGAADAGAAAGTTGAATTGAAGATPAQAGTPAARALRLEAREAEVVNVVKRAWASWMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBN7</accession>
    <name>A0A9P6EBN7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_462995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBN7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="300" mass="34430" checksum="625184CED7CA440A" modified="2023-09-13" version="1">MTACKVWLRSKSSYLQHSFVSSLLNILRSAARTCKMYSAQTANNGSYRRDAKISWRFKLIQERLERIWIIEYTIQIVSENSETWYSVQTLDSIASLARMIAVLRTLPLDTEESLGVVIRRLPLCDASSLPSLETMFRYPNSSISRRQDCDISFVQPSTQHTQFLAIQHFQYSLTSIEMKASIVFKVIDSRKRYSQTRGSRSGPIHLAPSLHFNLQHSFAFSLLCTSRRAARNSRPTDRPSPAKTTPTNLTLLVETHIDMRVRTMNVEHEIYANFFFSTPNTWRISAPSTGLRQPRLSQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBX7</accession>
    <name>A0A9P6EBX7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_492446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBX7"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="29293" checksum="C48D35A8C8A5D705" modified="2023-09-13" version="1">MGARIPPELYEEILFFLWGHTETLLACSTASPVLMVVSQKQLFSRVIIRSPLELVQSNIRFKRLYKVGGSASRFRELIETSPHLATYVKSFQIFDRDAQVAVPSTGDWLSIDQHIPDILLRLCNLKSLAIMYHFPPYHWQKNSAEFMSALVEVMQLPSLVGLSLKGIPMNLLLRGGTPNLKHVSFHPWKSQQILENIHLSSSLTSVKTITCRILHFLKIASINSISELLSKLSDSSRTLNLCRLKKLHIELKCNMSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECC0</accession>
    <name>A0A9P6ECC0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_817391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECC0"/>
    <dbReference type="OrthoDB" id="5803672at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040444368" evidence="1">
        <location>
            <begin position="22"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45278" checksum="BFC9CB001D2D12AF" modified="2023-09-13" version="1">MLANLWGVLFEPALRWVTLLAGKELELTPAVCIQKSSSLLKLALCMDKFTIPHAYYDPATYDLSQPVGSQREDWKRLVQQLLDVDTFGLCSAIPIPPSLKGIYTIEYFKGYCILHELTSPCGFYLKGWGYMIVPASDTRVSRDIHLAAPHPGYDLGTVEQVASMFERTGARSMLVAGRNRTALLEESSCIIPTSPRQYYYKTDPTHNNLEPFVDASLAVYHWQHRRAGCPSSSCAFIQIHAKGPSTCPDDTLFLSSGLGNSVASKAWYSDNTDRPVKRLKQTLKNNFSAWNISLPSDSSCALTATKNVVGRHINGVNSSRVCQQAATSRIASGEFIHAEQASDALKQEHYAAWSKAICEAFEPRCTEGTKIDRKSGLCTAMNSQVVDQDVQPALYEHIRNIYRLINAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECK9</accession>
    <name>A0A9P6ECK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen permease regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_435673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9526961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECK9"/>
    <dbReference type="OrthoDB" id="338854at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991">
        <property type="entry name" value="NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="407" mass="46214" checksum="8861EBE25EAF8001" modified="2023-09-13" version="1">MPEGDSFLPRIQSVFYAVFDVKQGARIVYQVPEDLIAVPPPNPFSTANGSDSLPPTPTAETPPHVHATPLPGGANLAARKSNSSLISPNSLHRPSGRLLASSPQKSPCTQRNLFNFGDISKYVIPPSPLCGRLVTCSTQRHRIMGFPVAILGKYDRVYFRYNFCFVFDREADLSCYEPIVRKVGCVLQACEEESEFLSSPTKSQAVHAILEQLYEDLNSYSETSIQIDRFNSIELKIFPFYPNPPQVKDWMVPLALINLSKRMEENWDLTMLKVCKHVDGVNHISRIAYLADCDISLARQTISHLLYYQVIMMIDIFQYSNMYTLRKNIQWLADEAHVREECGPYVTKPGRNISDWPKLLHLYSRLKPGKTIFEWMKVYDVDSSGIDVRRFTSFGVVKVSLRLHPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECQ3</accession>
    <name>A0A9P6ECQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-ribosomal peptide synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_769970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECQ3"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9526634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58117" checksum="E1FE8AA8B100F09A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED08</accession>
    <name>A0A9P6ED08_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AA9 family lytic polysaccharide monooxygenase</fullName>
            <ecNumber evidence="2">1.14.99.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endo-beta-1,4-glucanase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Glycosyl hydrolase 61 family protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_884763</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Lytic polysaccharide monooxygenase (LMPO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and/or C4 oxidation products. Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM).</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="2"/>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED08"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF19">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040301405" description="AA9 family lytic polysaccharide monooxygenase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="4">
        <location>
            <begin position="19"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9526648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="266" mass="29658" checksum="1B265DE0B529EDE1" modified="2023-09-13" version="1">MLNQTLVFAFSCLVCANAHGGVWKYEIEGKLYEGYKWWEPYEGQVSMQYRWPNRSPFWTAIDPDLACNVGGIPTSPNIYAPVHAGSVIKAHYDKNFSIPGEYPSSTNQTWSHTAGPIFVYMAECPEYDCGKVDPKAPIWFKVYEAGLMNGTWPAGYWAMAGLFHGETLDFAIPKDMKPGRYLIRHELISIEVGLKQLFPECAQIEVIGNGSSIPGSDYTRVAFPGAYSDSGTTIVDPGLNVTAIDFYVVHENDTHYPMPGPPLWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED36</accession>
    <name>A0A9P6ED36_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 7">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_857454</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a central role as a glucosyl donor in cellular metabolic pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 7"/>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED36"/>
    <dbReference type="OrthoDB" id="932129at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-alpha-D-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000001">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000002">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9526599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="501" mass="56517" checksum="47692FB2D796A965" modified="2023-09-13" version="1">MTSSLMPNFNARVRGTSHIDFKTATTGVAAKTMRNEISRLVATVEDPATKKSFDTEMQAFFYLFTRYLAERAKSVDLDWDRIKSPAEDQIVPYANLPQPKDSTNLNKLAVLKVNGGLGTSMGMTGAKSALEVKDDMTFLDLTVRQIEHLNTTNRVDVPLILMTSFNTHEDTLRIIKKYANQQVRITTFNQSRYPRILKESLQPCPKRADDDKKHWYPPGHGDLYNALLHSGVLDQLIADGKEYLFVSNSDNLGAVVDESILQHMIDSQAEFLMEVTDKTKADVKGGTLVDYEGSIRLLEIAQVPSEHVEDFKSVRKFKIFNTNNLWVNLRALKRIMDTEGMELEIIINPKTNDDGIPIVQLETAAGAAIKHFKNAHGINVPRKRFLPVKSCSDLLLIKSDIYSLQHGQLIINPQRMFETTPVIKLGDHFKKIQQFQKRFKKIPKILELDHLTVTGDVNFGRNVTLRGTVIVVANEGQRIDIPDGCVLENRLLSGNLNMIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED61</accession>
    <name>A0A9P6ED61_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_895898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157868">
        <property type="protein sequence ID" value="KAF9526738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED61"/>
    <dbReference type="OrthoDB" id="3001771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9526738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="51" mass="5666" checksum="BC6F022EA077618E" modified="2023-09-13" version="1">MATVHHLPVEVLSIIFDLLHPAVIEESELKVSVPQQGIITDDSPTEDLKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ED97</accession>
    <name>A0A9P6ED97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rad9-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_836678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ED97"/>
    <dbReference type="OrthoDB" id="60092at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="481" mass="53151" checksum="8D78EB259D835AE3" modified="2023-09-13" version="1">MQATLDASSLKTFTKALICLSKYGDELSVLVTPEFLSLSATNSSKSAYCRFKWEKQFFSRYMLKGKRVGNDEWGDEIQEVQNVTGQLMAKGLLSILRHRTVEKSVDKCELSIVEGNDQEGEEEDSLESKLILKLHCKHGILKTHRLLLLSLTTLLAPGVPDSTNESRLTIGPKGLKDLIDHFPVSKSAKSDPQLVWTFDETEVGLKSVESSIDSRGRGQLATELTISCEEFDVYEIYEYPVTIAFHLREFTATIAFADSIAQSLDLRFTDPAAPLFIDLEGDSFECMFVISTSQHHGAAHNGTQKSNSTQLANNKKRERSESETPRLKRPIKVVQPADLQVYNNQPRSDSRASSRIPGSMPPPSIVPNRSTFHAVASQGFSGNSQPQISTRQEEPLFLPSSSQMTAAEIEVLRATGLGIEDMDADELAEMLDGEGQEVDFSQRHLGPAGGDYMQMDEPDSLELVEDTGLPATQSSHCVDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE26</accession>
    <name>A0A9P6EE26_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE26"/>
    <dbReference type="OrthoDB" id="3222551at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="92" mass="10100" checksum="D1C8168BB0B87F48" modified="2023-09-13" version="1">MASLPSVLPARPAVQDDTTTLDQIHASVGKITSPEITPIYICTVHKCFRLFPNQRNLTAHSKKDHGLDAVDEKNVVTWNTLAPSNTTMNTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EED6</accession>
    <name>A0A9P6EED6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EED6"/>
    <dbReference type="OrthoDB" id="10638574at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="259" mass="29050" checksum="7127F95041035FCC" modified="2023-09-13" version="1">MSATSTLESYFYLSCHDGGSPDTRQITLPCQRGPSFEGIKKRVMEVANALAFICVKESHAIRLRFSGEGQPAVVHVAENNGVTPETKLYFEDVLSQLTALSQEQPRCQATEESLDFDSTINQPQRNNSWTNRIRDIRSKIISSETDEALFGKIEGTLGTIHQLASKYHTKGNKTTLCNIFGLLDLLDELVRRSESMDKIADLLRRIDFNTTNPYTPTEDSHENDDDDPDVDIQGSLKPGLPSRVSVDDFWPILLLKDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEG4</accession>
    <name>A0A9P6EEG4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">POP1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_855960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEG4"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="65"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="137"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="6">
        <location>
            <begin position="513"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="7">
        <location>
            <begin position="761"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9527535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="850" mass="95990" checksum="4AD6E01927A96522" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF52</accession>
    <name>A0A9P6EF52_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EF52"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="334" mass="37277" checksum="EF02880D165933F4" modified="2023-09-13" version="1">MAANYLVVGDKVIHMMFGLYLWEWFTSLNFDWQLISGKKRFKWPLTFYFLNRYAMLICAISYLILWDVQNPSVHIDCKFLFALVHLCGSGSLGLASANLAIRTIAIWNQNIYVIIGLTILLLAHLGLVIADTADATKTAELQVYGSDTAGCVNASTGDWLRIIVSATLIIDFVVLVLNIYKILQTSKAVYGDATLFKYRKQGFFKLSYIVLKQGVVYFLLAFSSNAAQIVILSIPALRPTGMNRIFILPSYIIATIVACRAVRDLTNFIYDGSEIHVVSTTRSGISGNRRLNPARSDVKSSPIRFALETEQDGVLVQMETISRNDSLHVKSPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFA8</accession>
    <name>A0A9P6EFA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFA8"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF72">
        <property type="entry name" value="IM:7136021-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="431" mass="48536" checksum="519126C5AFF96332" modified="2023-09-13" version="1">MSFNTIPFELIAEIFEQAAVVDFLAPVTLSHVCNGWRKVAISDPSLWTTICIETGQTKEITTCTFVETFLNRSKSLPISITLVDRRGSKLITNTINLLAQHSFRWTSLKLTHSGPNCLKTLLQPAPILRDVSITTSHLDDTGFYTISRFLELLPSMTTLSLNFKMQPAIRLSSIAPSCPHESLLDLTLKDWCPTPLLAMLGHCVRLQTLSIHGLDLHEPPPVYTDQNPRPINLPDLRKIYIYQYCLNDSICVLFDQLTCPNLRGLDISSGFVDYFPFPKTSVASFLRRSACPLTSVLFEMVQITEDQLLECLEACSKTLEYFDVIEQRDVFCVGDKLLNKLTAGTEHHDGAPTRCTTLCPRLRAFQVNDALDCQDGALAAFLRSRQPSNIHNLACDHCTPLDKASIRIRKKFRENLGSDIDYLKENGHWVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFR0</accession>
    <name>A0A9P6EFR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_366694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFR0"/>
    <dbReference type="OrthoDB" id="3267813at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="153"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="434" mass="44258" checksum="F55340991E15D8C6" modified="2023-09-13" version="1">MPLGSAQEAQVWLHKSPHRMMGHVSTLQKTSLLCTSIALNPPIRLYSVRIQGYGGILLPLLGSLFHFFSLSLPLRINPSSSDTNFQGVIPGGQSFAISRSDISQVQGQGTGFNWKPSLRAGTTLLLVGGDGRGNGTAGSSLFSVGAGIAPDQSCLDANSPSSTPGQPAGGSYPTDKSGSGTGGGDGGGSSKSNTGAIIGGVIGGILVFILALLAFWFWKRKQKKARRVKERPDLLNADDDDDEDERRRRGARPNELPQYYQPEPFLVPDPTVGGRSSHDGTVSATNDERRPLSAGTFGDSFYTRATTPDGLGGTAAGSQHGDHYSAGASSANGGRRKGGAPRPMRPVNIIQHDDAGPSGAPPPAEETETIELPPAYTALNKSAVGGEGGAAETEAGRAGKAGRGGEERLGGSSAAAAAPGGSSSGAGGSSSAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFT9</accession>
    <name>A0A9P6EFT9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_814250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFT9"/>
    <dbReference type="OrthoDB" id="3262423at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="60838" checksum="F7282B70C0F22121" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGJ6</accession>
    <name>A0A9P6EGJ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Guanine nucleotide binding protein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_869265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGJ6"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF360">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="238"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="430"/>
            <end position="433"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="519" mass="59359" checksum="F2D3A137C9F17FE8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGY0</accession>
    <name>A0A9P6EGY0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Formate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_852605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FNT transporter (TC 1.A.16) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGY0"/>
    <dbReference type="OrthoDB" id="4829at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015513">
        <property type="term" value="F:high-affinity secondary active nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015707">
        <property type="term" value="P:nitrite transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="FORMATE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520:SF6">
        <property type="entry name" value="FORMATE_NITRATE FAMILY TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="257" mass="27957" checksum="DAD1A61B15D850B7" modified="2023-09-13" version="1">MSFNVPSTLTPDEVASVMVKLGVKKHKDRYASIFFKAFLAGAMLSFGGLLSEVLQGGAAGLTASNPGIVKVLGGFVFPVGLVMIVLQGQELLTSNMMVFPMAVAKRAVPWWSLPLNWVIVTFGNLTGSLFFAAVLVKYSGIVSADPYATFIKNFALHKAKDPEWHQIFLRGIGCNWLVSVAVWQAAGARDTLSKIFAIWIPIWIFVACGFDHVVANMFSVPLGIMFGADVRVPIDFLATPFRTTLLHDLPLTLLIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH34</accession>
    <name>A0A9P6EH34_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_835591</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH34"/>
    <dbReference type="OrthoDB" id="274944at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="44"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9528869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="129" mass="13727" checksum="70391A8E288BB6C8" modified="2023-09-13" version="1">MADRGRGASGGRGGSGRGGPVRRPPGGPHAQLASGPPGEKPKREAILDLSKYVDERIRVKFTGGREVTGILKGFDQLLNLVLDDVTEELQQPEPHIRKLGLAVLRGPTITVLNPVDGFEEIANPFGAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH73</accession>
    <name>A0A9P6EH73_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_257719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH73"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="172" mass="19488" checksum="E229D9285FEE126D" modified="2023-09-13" version="1">MWYRYYRFVSHIPLLSFVFLAFRSTSTISYRRFGRSIVSLPASLFLVPLSHLKDTPSLFCSILVFTIQAQSLTLLSLSSGPDLLSRQVIKPRCPNSTYCKRDFRPPNPAMIARDYLVTTHTPLQALDASDPLSTTNARDCFRHLHYAPFLERACAILILSTLSLDPTLSSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHH1</accession>
    <name>A0A9P6EHH1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_789538</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHH1"/>
    <dbReference type="OrthoDB" id="3357304at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040322550" evidence="3">
        <location>
            <begin position="17"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="666" mass="73779" checksum="D46F7713D7633301" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIC6</accession>
    <name>A0A9P6EIC6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-Aspartase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_906063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIC6"/>
    <dbReference type="OrthoDB" id="10051290at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9529392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="739" mass="80039" checksum="BAA94E2A6D40475A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJH4</accession>
    <name>A0A9P6EJH4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SURF4 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_851376</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9529977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJH4"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9529977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="310" mass="34823" checksum="CC43AA2434A93543" modified="2023-09-13" version="1">MASRISIARPQSNYQSYDPHGLSNSRPSSGYRAADPDDPREKLKAFSKNVEDHAEIYTQPLKPHLPTIGRFLIVVTFLEDALRIITQWGDQIWYLQTHRSFPWGISHIFLIINVITMLVGSGAVITKKYTEFAVGGLLSVVVIQGFGYGLIFDLNFFLRNLSVIGGLFMVFSDSMVSRKTPFAGLPTISENDRKKYFLLAGRVLLIFLFLGFILQGQWTFMRLVVSLFGIGACGMVAVGFKAKWSAVFLVLVLSIFNVFANNWWSVHSAHPQRDFLKYDFFQTLSIVGGLILLVNMGPGGFSVDEKKKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJR0</accession>
    <name>A0A9P6EJR0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane bound O-acyl transferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_904974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJR0"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF67">
        <property type="entry name" value="WAX SYNTHASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Wax synthase" evidence="7">
        <location>
            <begin position="238"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="47300" checksum="7608C88FFA68EE77" modified="2023-09-13" version="1">MLSKLGLPLPLDPSQKLPFRLSTLAAAEFLLVLSYAIQSLPGRLSIFVPTACICLWMLACTRADFPPANHPLGWRVGIGCRVASIFLFASTSVLEKVMVGSAEKRKHSNGDSVLRNLWSGVQTWFNPRCINTASEPRSSLPPRPHITNRRSSFVIRQLLWGSFHFFLMDISTTLLHFYDIRRQTPLAPKSSLDFAFNHKFGLLTSVSYFGTLYTTLSYMHYALSAFSVGLGITNPCDWPPLFNFTFEACTLRKFWGTFWHQMFRRIFTTHADFFSELLHLPPDSQITRYFKLFCSFGLSALLHLGGDGLALQSVSKSGCVKFFMLQAAAIVLEDNIIGLTSKLPAQRNLRRLLGCLSVLIWFGSTLPIWIDPLLDAGYVDTLNQGYFSPAMGLWKGVWFRQEFNTRIWDEIFRVQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJR1</accession>
    <name>A0A9P6EJR1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fruit-body specific protein a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJR1"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040450739" description="Fruit-body specific protein a" evidence="1">
        <location>
            <begin position="20"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="52219" checksum="8F68D9F17B87D2BF" modified="2023-09-13" version="1">MPRLLLALLHTLLLVTAYAFNTSNVPDNLPDIPSNRVDLTRTLTDATTIANTVAQVRQKAGASGNPNHPVPETVVTARDGKLTSKGQLTSNATSLAGLFERSKRSPSDYILVFGGSPVNSEARDASIEGTAYLTFTLVSNATYNIGDCLAFCDSVRECVFANIYYEFNNDALDHRESSNLKCAVYADTHTAAEKTNYGGQQSEPLPAGLTYIQQSSGFSKRTLVDPTDPDGYSLVFGPTSGANNAPGYMGFSFLDRYDVAACAKECNQRGADGQGGACKYFNIWRAVVNGNPTTYTCSMYYLVADQSTATNTGQGDLKVTYSRGYKRLSYAEDGGFESLQKLCFGFCWTQLDSSWAGINSFGGFDEAAIFYYTPYAHSGGVIGMLGSLGNYDNLPGTLTPVKPLKTVAGKKYLIEFFYASTYSGSNKGANAYVDVSWNGQVVNTVKGYSTWKPASVEVVGKGGDTIAFHGGAGSAIVFLDDVGVFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJX1</accession>
    <name>A0A9P6EJX1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_851421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157842">
        <property type="protein sequence ID" value="KAF9530004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJX1"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="50"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="381" mass="42288" checksum="D8732ECE4241E1E6" modified="2023-09-13" version="1">MAQTQLKQIIVLGAGVVGLTTALKLQQEGKYRVTIVAEILPSDHKSIRYTSHWAGAHHVYNPLNSTQLNEYEKETFKIMWEMSAPGSDAHECFLRINQTEHFYHPRELRGTTDPIESFPDFRYLTQEELPPKCIYGAKFRTFTIDTPVYLNYLSTRFLSLGGKMMRGSVMHINQVLEGGTSLLPGGHEKDQLPDAVVVCVGLGARFLGGIEDKNLYPIRGQTVILRAPWVRTGITETYGGQGTGDSVTYIIARRSGDVIVGGTRDADDWYPKPREETMEAILTRALSLCPHLAPPEIRSVRTPTVDDILPLVVGEGCGLRPARKGGIRLELEWKDGKQVRRKGKLPVIYNYGHGGYGFQSSWGCASKVLELVATALSTTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKF3</accession>
    <name>A0A9P6EKF3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_881961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157838">
        <property type="protein sequence ID" value="KAF9530715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKF3"/>
    <dbReference type="OrthoDB" id="5399006at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43431:SF7">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G14000)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="27775" checksum="05D27032CAA02F97" modified="2023-09-13" version="1">MSSQTAKRVAVVLGLGNGSGTGGATARLFAKNGYEIALIARGGDTLEKLAKEILSNGGHAKAFSVSSYSHEDITNAWSAIHKAFPKPEYVIRVAVFNGGSGVFKKFLDVTPQDVQTALQATIASAFSFSRGAILAFKDNDIEESNGKRGALLFTGATASIRGNVLTSGFAPGKHGLRALSQSLSKEFGKENIHVAHAIIDGAILMDGQRQRRNDPAWEANEDVRLSPESIASSYLYLVNQDRSAWTWELDLRPAHEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKW3</accession>
    <name>A0A9P6EKW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase pc-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_849949</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKW3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9530970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="590" mass="67473" checksum="FC6BC32DEFD6F5B2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELI6</accession>
    <name>A0A9P6ELI6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_123170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELI6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="99" mass="10933" checksum="36B613002B0EDB25" modified="2023-09-13" version="1">MVTTSQLKVSRFASAFPYTAPAAFIELVSLGTVILLISPDIRGPKHLTFHPSLCQILMNTRQELFDLFCNNSVQVPVGPLDIELGASGLSLRQYQWSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMN6</accession>
    <name>A0A9P6EMN6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_630486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMN6"/>
    <dbReference type="OrthoDB" id="3267648at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="452" mass="50971" checksum="A100423EB1F22382" modified="2023-09-13" version="1">MTTTTGFKAFCSLRQHLRPVRVRNSCRPMHWKPNSTQSVSKVIQTSLLTKPEFTTKLKEPDPFVSSNRHILVVDLDANSTDHHAFSGLDPHHDEALELVKSEAFRAELETLREEQPDLDPTTRYVDNCGVEVDDAYLVYEATNEMLARRLRRLVAADRDLPKDAQIDAVVIGPDPGPTMWRALDGLSPKHLEISAGWDESIDADTIDTLARPWDNLESLTLRDNGDGWMGQYPEFFTRIKSLTLEYCAGFDFIIDHVPADAKNMPLQMINLKAVGNDAMGALCGAVEHVPGFSGRLQRLYLTSNRSNYDCSTGDFRESLKQCTAISDLFLALGNPPNYNPEFTLKKSDNKNNDTKLTWVFPQSVESLSFHCSTSDAMLADLDVWIDASSRNDWLPKLKNITIRTDGPEHNALREVQEGKPSAERRKLFQHKIDKIYANLRAIRWSSPVTISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW0</accession>
    <name>A0A9P6EMW0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_759126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW0"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF10">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="62" mass="6416" checksum="2820E32DF76D91AA" modified="2023-09-13" version="1" fragment="single">STGSIDVSRFLIDQKAEIDTTDGSGWSPLHIAVSAGHEAVVQELVGAGADVNKKNNKGITPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMY3</accession>
    <name>A0A9P6EMY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_846311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMY3"/>
    <dbReference type="OrthoDB" id="74910at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000003">
        <property type="entry name" value="Fumarylacetoacetate hydrolase domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="10"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="24608" checksum="1C06244B51F0F7C9" modified="2023-09-13" version="1">MASFIRNGKKIVAIGRNYVAHAKELNNAVPKEPFFFLKPTSSYLPSGGKLEIPHGILAHHEVELGLVIGKSGRNIPQANADFHIAGYTLAVDMTARNLQDRVRKAGLPWSAVKGFDTFTPIGEFLPKSRVPDAHDLRLSLKINGDVKQNGTTGDMIFRIPRIIEHVSSIMKLEEGDVILTGTPSGVGPVSPGDKVECALLNPKGEQLLSLDFEAIQRDGGYKFQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMZ0</accession>
    <name>A0A9P6EMZ0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of Vps4 activity in the MVB pathway-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_847880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMZ0"/>
    <dbReference type="OrthoDB" id="29853at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.60:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein IST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161">
        <property type="entry name" value="IST1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161:SF5">
        <property type="entry name" value="IST1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="252" mass="28235" checksum="E46BD55193F0501B" modified="2023-09-13" version="1">MLWNATKAKVQLRLSVQRLRTLQQKKEAQAKANRRDIATLIEKGKLETARIKVETIINEDVHVELLELLELYCELLLARFGLLDMNTREPDPGISEGVCSIIQAATRTEIKELHILREILMHKFGREFAVAVMENKDDCVPKRVMTKLTTTTPSAELVDAYLTEIAKAYGVPWSASGPIEIPEAVTDEKKADDSGSVEGQKDNEDVKAKTEISPSNPDLPTLSQDTKKPTSPDPPEDEFDLLSKRFAALKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMZ7</accession>
    <name>A0A9P6EMZ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_903985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMZ7"/>
    <dbReference type="OrthoDB" id="2834207at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="106" mass="11922" checksum="502366DB9A6FD94D" modified="2023-09-13" version="1">MFSRLATSLSSATRLLSTTSALRMPKPYTPADWRIIETSPSGLERTFTNDKTGEETWYTPDGMTASEILKIPGAKKYWKNESDVQKYIKEMAAEKARSDGQDINDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EN65</accession>
    <name>A0A9P6EN65_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_585196</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a monoacylglycerol + H2O = glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15245"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17408"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family. Class 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EN65"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="6">
        <location>
            <begin position="85"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="307" mass="34197" checksum="24D4B8C84ADDFE82" modified="2023-09-13" version="1">MYVLFCAWVVNWGTDPRAGQILERPYSPTAQEITLVRNGARALAMEFESFIDLSLTPWDPTSKTPSAGPFAGVFKPKTGEPFLILAFKGTTYEWEVNTDALFGAVAVNPEILYGLKAHQGMSRNLFKPFEATGRTESAFDIIFAKLEATAANIKGNGTRKIPVYVTGHSLGAGFAILAYMEFIRRLEIKPSNNFSLQDLWNYGAPRVFLAGGAQKMAAIVKDTNFHVYRAANFGDLVPTLPPIFGTHVDIGYKIDPEAATPEEYITERPSELDGRKPDDPVPSPDTWQKHWPPVYYRGIRKYLNPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENH9</accession>
    <name>A0A9P6ENH9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_672198</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENH9"/>
    <dbReference type="OrthoDB" id="73614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF6">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="162" mass="17775" checksum="4E5AD4A67204D259" modified="2023-09-13" version="1">MAPGKGWFNLESGTSVIPDSTFFEGEPAFKFLNLSRTTRLYGFAGCFIAGFVLSLLGTIFLTFGGLIMFAIFYALGTVVSLVGTGFLIGFFNQLKMMFKPIRVVATVILIASIGLVFVGAFVLNNGVLCLIFVFVEFLAYTWYTLSYIPYARTGIKRMIGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPB6</accession>
    <name>A0A9P6EPB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mucoidy inhibitor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_635276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPB6"/>
    <dbReference type="OrthoDB" id="10068793at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02231">
        <property type="entry name" value="mucoidy inhibitor MuiA family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005:SF8">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4140" evidence="2">
        <location>
            <begin position="24"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="1">
        <location>
            <begin position="217"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9532702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="64976" checksum="36B3033DF2A3F3BD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPS4</accession>
    <name>A0A9P6EPS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_832506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EPS4"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000077">
        <property type="entry name" value="TBC1 domain family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="508"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9532912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="877" mass="98821" checksum="D5DF8B31C5A856D4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ81</accession>
    <name>A0A9P6EQ81_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_784156</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="255"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="321"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="558"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="669"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="767"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="807"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="967"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="610"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="629"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="688"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1304" mass="142430" checksum="2D09AFD675C739CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQR6</accession>
    <name>A0A9P6EQR6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Dipeptidyl peptidase 3</fullName>
            <ecNumber evidence="4 15">3.4.14.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 15">Dipeptidyl aminopeptidase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14 15">Dipeptidyl peptidase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_846716</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.</text>
            <dbReference type="EC" id="3.4.14.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 17">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15 17">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase M49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.4" evidence="4 15"/>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQR6"/>
    <dbReference type="OrthoDB" id="4694525at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.30:FF:000001">
        <property type="entry name" value="Dipeptidyl peptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.30:FF:000002">
        <property type="entry name" value="Dipeptidyl peptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005317">
        <property type="entry name" value="Dipeptidyl-peptase3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007828">
        <property type="entry name" value="Dipeptidyl-peptidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 15 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15 17" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="16">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR007828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR007828-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR007828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9532974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="697" mass="77470" checksum="AD8E2957AC645B72" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQZ4</accession>
    <name>A0A9P6EQZ4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Nuclear transport factor 2</fullName>
            <shortName evidence="3">NTF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_880080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EQZ4"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="4">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="122" mass="13627" checksum="045C44F8340194EB" modified="2023-09-13" version="1">MAADIVAIAKQFTDFYYSTFDTNRASLGSLYRDTSMLTWEGQPIQGRDSISEKLTSLPFASVQHKVTTSDVQPIQNGIVVYVTGLLVVDDSTNPLQFGQVFNLTQEGDSFFIQNDIFRLNYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER79</accession>
    <name>A0A9P6ER79_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_845307</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER79"/>
    <dbReference type="OrthoDB" id="1110759at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="5">
        <location>
            <begin position="32"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="196"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="263" mass="26941" checksum="854E5272EDBF42F5" modified="2023-09-13" version="1">MVSRRATATKAAPVKKPAPAPKAAVAKGAIPAHPPWVDMIKECIAHHTEDARIGVSRPQIKKYVESKYGLDIGAAQTTQLSKAIASGEEKGVFVLPKGPSGRVKLTPKAKTTETAAKENKPTSKATTSKTTTTKKPAAKSASTSRTTTKTATKATTVKKPAAKPKSTTKKATATTSKASAVKKPAAKPAVKKAPAKPKATTTAKKTTTASKRAPAKKAVTGTSSTTKAKTAAKKAAPAKKAPAAKAKPATKAAAPKRTAPKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERC4</accession>
    <name>A0A9P6ERC4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_845617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERC4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="51" mass="5654" checksum="9BFD28C90A5F2ED0" modified="2023-09-13" version="1">MSLQNSRLVDQQAAEATKKKVLEDVLYSLGATPASRTGGSRHWTKKPKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES02</accession>
    <name>A0A9P6ES02_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Pex12 amino terminal region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_866449</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES02"/>
    <dbReference type="OrthoDB" id="1701437at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF4">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="300"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="389"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9534186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="432" mass="48811" checksum="71C1C79F05A2DF8F" modified="2023-09-13" version="1">MSGLPAVLENAWNSALPVFQNVKNVLVSENSLETPRITRVGQLDSELLDQELTNLLQEPITKALALLNSRFKSSFQPELALFIQLTLYKLSIWNTGASYGAKLQDLRYVVTGSSTGNSTPSGLPRKTLLLHGTLTFLMPYFHNKLRNHALSHAWPDAPSSDSRRKAWVMLNSVESMYSLLGLVNFVAFLWGGRYRTLADRLLCMRLTPSRRSVKRDVSYEFMNRQMVWHAFTEFLLFLLPLISARAVRRRFYKLTTMLSPSLLLSLSPFKGILKPSSGWRQGERPPQKRGKYWALPDDQCAICAENIAFNLNVSDSTNAFTSFTSDPTLNSPEDAPAHPIHNPYQTTCGHIYCYQCIAERMLRIADEADDEEQGWECLRCSEQVKESRRYQVEVTESEGDMSASEYEFSSDLDLSTDLSGSMGTYSESGFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESB7</accession>
    <name>A0A9P6ESB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_844348</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESB7"/>
    <dbReference type="OrthoDB" id="16982at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000014">
        <property type="entry name" value="Cation/H+ exchanger protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF10">
        <property type="entry name" value="VNX1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="548"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="951"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="986"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1019"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1051"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1084"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="domain" description="Inner membrane component" evidence="12">
        <location>
            <begin position="212"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="559"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="950"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="787"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="917"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="833"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="918"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1140" mass="124229" checksum="7AD9A2155D630C9D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESC1</accession>
    <name>A0A9P6ESC1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Snare associated Golgi protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_889262</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESC1"/>
    <dbReference type="OrthoDB" id="3364966at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF21">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="212"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="454" mass="49830" checksum="5AF2E4DE41893BCB" modified="2023-09-13" version="1">MESTLSPPKPPRSRAHSSTLCSPITLASLGRRRSNSCLTANIDNEQCPESHTPPTVLDQQQQPATSTMTDWLVSGFLRWLHFPQKHSFSWSTPSSPRSSTDESILPLSASATTLTFSVPDPKELQKLNSWRFRLSPAHAPIFAVILLLPISTAFVLWSLSTLPISMSWPHTISDLAQICRELHGYSQSGPGPLVHVVSVMAISAVWKHAWSIPGSVLWNVLAGALFSPFYATILLTTLTTMGSACATLLSKPLGPFLSSLSPRALEMTRHALGGESDLDNSGNQSSMTKSSAWVRLSILRLIGVVPWSGINIACGVCNVPLADCMLGTFIGCLPWTAVTCQIGDILQQVASTPSPTPQSIQSLLTTPDIAFKLVFLSVISLAPILGRSRLSAILSSQPTDDERKPRWVWVQEWRTKIRLPSRSRQREQGRKQDQLTLDTLVSEKRRFEDSEYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESP0</accession>
    <name>A0A9P6ESP0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">[histone H3]-trimethyl-L-lysine(4) demethylase</fullName>
            <ecNumber evidence="4">1.14.11.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">CPB83DRAFT_843708</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl(4)-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2</text>
            <dbReference type="Rhea" id="RHEA:60208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.67" evidence="4"/>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1678912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000014">
        <property type="entry name" value="PHD transcription factor (Rum1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000016">
        <property type="entry name" value="Putative Lysine-specific demethylase 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048615">
        <property type="entry name" value="KDM5_C-hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013637">
        <property type="entry name" value="Lys_sp_deMease-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF33">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21323">
        <property type="entry name" value="KDM5_C-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08429">
        <property type="entry name" value="PLU-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="17">
        <location>
            <begin position="163"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="16">
        <location>
            <begin position="228"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="460"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="18">
        <location>
            <begin position="614"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="322"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="975"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1637"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1813"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="975"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="1656"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="1673"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1702"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1750"/>
            <end position="1760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAF9534118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1851" mass="209343" checksum="CB69270862D12E60" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESS3</accession>
    <name>A0A9P6ESS3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_866824</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESS3"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000018">
        <property type="entry name" value="Pyridoxal phosphate homeostasis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="5">
        <location>
            <begin position="24"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="29218" checksum="EE233FF35CBCF4E0" modified="2023-09-13" version="1">MSESSNVELPAADRVTELRQSLAEIRASVKKASPLNSSPTLVAVSKLKPASDIQACFLDNQLDFGENYVQELEEKARILPPDIRWHFIGTLQSNKAKNLAAIPNLYSIQTLGSIKAATALNKALPNNRGSPLRVLVQVNTSGEDAKSGLPSLTPSSTLAESELIALIKHVVTSCPKLRLEGLMTIGSLEQSIAASDSQENPDFERLKETCNIVSKYLQTTFSDSTQNWGDETTGRLLLSMGMSSDFEAALASGSDIVRVGTGIFGQRPAKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESS5</accession>
    <name>A0A9P6ESS5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic peptide chain release factor GTP-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ERF-3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">ERF2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Polypeptide release factor 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Translation release factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_844115</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESS5"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018444">
        <property type="term" value="C:translation release factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000017">
        <property type="entry name" value="Eukaryotic peptide chain release factor GTP-binding subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000503">
        <property type="entry name" value="Peptide chain release factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000061">
        <property type="entry name" value="Translation release factor eRF3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003285">
        <property type="entry name" value="Sup35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01343">
        <property type="entry name" value="YEASTERF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Tr-type G" evidence="15">
        <location>
            <begin position="127"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9534359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="570" mass="62550" checksum="614463F8B15E6F45" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETC1</accession>
    <name>A0A9P6ETC1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="7">1.1.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_866288</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2</text>
            <dbReference type="Rhea" id="RHEA:21252"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16782"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the L2HGDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.2" evidence="7"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETC1"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF4">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="4"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9535005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="426" mass="46989" checksum="39293752B0BC27C6" modified="2023-09-13" version="1">MTTGVVGLAVAQRLSQSFPTKTTFLLERHTRAGEEISSRNSEVIHSGLYYPPESLKTSLCLRGRDLMYERCKAYNIPFKQIGKLVVAKKDQLSYIEGLHAKSLKLKWPKHSPTSSENNTVLPTKLLSEEEVRKLEPDLSPHIVGALWSPTTGIVDSHSFMESLEKDILESDTSEVVYASEVVRIDPYKRSGSASNVPDLDAAEDGWVVQASAAGDENYAVLARNVVNASGLASTLVLNSLLPEKDRIPMYYARGSYASYHGPGVSNIKHLIYPCPQTGPNAHAFESLGTHLTLDLQGKIRFGPDIEWVNPPEVTEAVERDAEFWLKIMVPDDSRLQQMHQAVTDYLPGVTLEGLQPDYCGMRPKLIPPGAGFQDFMVQKDYPSMDAKQSRSGAMVSLLGIESPGLTASLAIAEMVVEDMLKREKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUD4</accession>
    <name>A0A9P6EUD4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_231382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUD4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="221" mass="25492" checksum="8C2C38B6215BBE35" modified="2023-09-13" version="1">MFAMNLRSMIEAIAPFVLRCFNLNASLPSPRRQHYGRIWEPRLPSNISPSRKLEKPPDESDLIQCLWLVPSLTKLTLDGMPSSNIFWHLLPRHILSDKEHLTSRRIFLPNLQHLKLTGRKTFPWSMICSVMPIVSHSDRYSRPLSHIETTFSNVDYYAEVEPNTISRQDLQTLQERGIIFIIHDNQDHNFIDLSKSHLESHGQKALSCSELRDDPDPGDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUL3</accession>
    <name>A0A9P6EUL3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_912805</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUL3"/>
    <dbReference type="OrthoDB" id="784962at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="180"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="387"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="5">
        <location>
            <begin position="557"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="634"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="694"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9535567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="707" mass="78389" checksum="B2A8372DED9B5162" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVA8</accession>
    <name>A0A9P6EVA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_736653</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVA8"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9535389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="273" mass="30691" checksum="331C86FF34B9A9AF" modified="2023-09-13" version="1" fragment="single">FQWIRGTMIGKGSQGKVYMALNVTTGEIMAVKQVERPGAFADGDGLRRIADALREEQETLRDLNHPNVVQYLGFEENRQTLNIFLEYVSGGTIDSCVKAFGKLREDVTKHFTRQILEGLAYLHSEGILHRDLKAANILVMDSGACKISDFGISKRNSRAFSFTGTSYCMAPETLSPGVHGYDAKVDIWSVGCVVQQMWTAMRAWLDVDFLTVWCRLGEGELPPLPSDVSLSMLAHHFRQECFQIAPDCRPSAEFLLLHPYLDLPPDWEFPGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EVG0</accession>
    <name>A0A9P6EVG0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glycogenin glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.186</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_913069</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Self-glucosylating initiator of glycogen synthesis. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23360"/>
            <dbReference type="Rhea" id="RHEA-COMP:14604"/>
            <dbReference type="Rhea" id="RHEA-COMP:14605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140573"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56560"/>
            <dbReference type="Rhea" id="RHEA-COMP:14606"/>
            <dbReference type="Rhea" id="RHEA-COMP:14607"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140574"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="10"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EVG0"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000092">
        <property type="entry name" value="Glycogenin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="446"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="597"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="637"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="739"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="637"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="765"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="776"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="855"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="870"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="976"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9535648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1056" mass="117045" checksum="A83AC652AAC952FF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI18</accession>
    <name>A0A9P6JI18_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="13">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CPB83DRAFT_778144</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="13"/>
    <dbReference type="EMBL" id="MU157990">
        <property type="protein sequence ID" value="KAF9521778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI18"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF12">
        <property type="entry name" value="EXO-POLYGALACTURONASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040336631" description="galacturonan 1,4-alpha-galacturonidase" evidence="16">
        <location>
            <begin position="23"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9521778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="47332" checksum="82D72A6B795C0B4A" modified="2023-09-13" version="1">MRGAIVSSFLTIFVLLLRSTAAAEEKTCRLRPLGHGKDDTSQVEKAIANCGKHGTTIFETGSYNITRKMKWDLLSSKVDLKGYLNFPPNIDYWLNPNNTYRAIIIQSQASWFVVTGRDFVIDAHNTGGIQGNGQKWWSFYAGKPHNDGDGRPVSLSLVNVTRGEVRNFRIESPPFWANAVSQSSQVTYDGMYTNASSLDPAWEGQNLVLNTDGINTYRSSFVTLKNWDVTCGDDCLAIKGNSSNIVAHNITCRGGNGIAFGSLGQYAELVDIVENVDLKDIHVTRIDPKIQPLMQWGVMFKSWSGSVKGAPPTGGGGGTGYARNITARNVYVDRVDTPIYIHQTYNNDEHSGDLPSKLNFGGITYINFTGTASSDKIVDLQCSPGAFCHDITFKNINVTAPAGVAPQYLCLNTQNIHGLSGEHELGDTCMIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JI22</accession>
    <name>A0A9P6JI22_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157996">
        <property type="protein sequence ID" value="KAF9521720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JI22"/>
    <dbReference type="OrthoDB" id="3055188at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="1">
        <location>
            <begin position="11"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="258" mass="29612" checksum="A062456CAB5009FD" modified="2023-09-13" version="1">MWRAALGDGKISFRKIIALEYAFPTKEADLGLASQCFSAVIEEFKDKGLIFEEGYQQNRTMDGIVFAEGSTYRGKLKIQAAEFVQQYYADDLKTTHFYKNQQGNHADIATKVERLVGIQSMFHKDGVDKQGKANNFMHPCIRDLCIDFYYSKKQDGLAHHFPNEFKDFIPERAVALFIAVIQCALDEYKSGVRTMVDFCGDTYLKFYRMTIQMFAVINSKPNHHAKWKDCRMQWARVAWAKHNPTEDAGDAILTVDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIH0</accession>
    <name>A0A9P6JIH0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_865043</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="MU157963">
        <property type="protein sequence ID" value="KAF9522065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIH0"/>
    <dbReference type="OrthoDB" id="3370at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17956">
        <property type="entry name" value="DEADc_DDX51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="171"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="456"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9522065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="634" mass="70404" checksum="9010A708843AFDC7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIS5</accession>
    <name>A0A9P6JIS5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_113326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157947">
        <property type="protein sequence ID" value="KAF9522393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIS5"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="240" mass="26131" checksum="975CC16CAA7C5C17" modified="2023-09-13" version="1">MEFYHMKLPTTAGFTPANPLKTIELQKRHELEKRQAELIPMAIGVWLLIAGESASKSIITAIAKSLKTVFGKDSTPWHSGGDRCTISFSTHGGAECQATINAKGVKSDRPSQSWNVCPWINPESTGPPIQYFSDNGVGDYSIQFTATDKVAWSGIQGTEKCIMEGLCHPRITFYRKDHSIVLDTWASLGDPTQGLYFADFGGLCGNGPIKNQFKSNGMVMGYDCGIPCEGDTDLPSTEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIU5</accession>
    <name>A0A9P6JIU5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_864166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIU5"/>
    <dbReference type="OrthoDB" id="2151417at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040343443" description="Small secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18189" checksum="2959C6B531D5F5B9" modified="2023-09-13" version="1">MHFTQLLVTFVLSLLAFTSALPVKLQARAFQEQDYADFQISDGTGGDAKAKADAVFVTPFAGVNLATVTKAERDAVEAMRQAAEKAETDQFNEQIDAASGAAADALSVGKTKNKVLKLTGEVQRIQIDIAQAKASGDDLSSLQEQLTAEQTKLSTNIALDVKNKGKASKGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIV4</accession>
    <name>A0A9P6JIV4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_116942</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157951">
        <property type="protein sequence ID" value="KAF9522304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIV4"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046616">
        <property type="entry name" value="DUF6729"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20499">
        <property type="entry name" value="DUF6729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6729" evidence="12">
        <location>
            <begin position="170"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="11">
        <location>
            <begin position="543"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="869"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9522304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1029" mass="116236" checksum="07C8952FEB3D4C7D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJC9</accession>
    <name>A0A9P6JJC9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_799685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJC9"/>
    <dbReference type="OrthoDB" id="2915840at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="4">
        <location>
            <begin position="11"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9523127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="582" mass="64713" checksum="75EAF2BE8261E5F4" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJQ3</accession>
    <name>A0A9P6JJQ3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Probable electron transfer flavoprotein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_863412</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </cofactor>
        <text evidence="7">Binds 1 AMP per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157924">
        <property type="protein sequence ID" value="KAF9523160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJQ3"/>
    <dbReference type="OrthoDB" id="276685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000011">
        <property type="entry name" value="Electron transfer flavoprotein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294:SF8">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="8">
        <location>
            <begin position="32"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00070315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9523160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="271" mass="29356" checksum="FCBBDEB2A4EF144D" modified="2023-09-13" version="1">MRPSPRRLLNILVPVKRAVDYSVKIRVNPQQTGIDTNVKHSMNPFDEIAVEEAVRLREKHKESIKSIRAVTIGPSKSLDTLRTALALGADSAIHVQIPDTAPSPEPLAVAKTLRSIIQKKNAEASGEGDKIDLVILGKQAIDDDLGVTGQMLAGLMGWSQATFASKLEVDEGKQEVLVTREIDGGGEEIRCKLPLVVTTDLRLNEPRYASLPNIMKAKKKPIEKLTPEDVGVDFTPQLETVKVSEPPTRVGGGKVANVDELIAKLKDAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLB1</accession>
    <name>A0A9P6JLB1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_562882</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052650">
        <property type="entry name" value="Zinc_finger_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36886">
        <property type="entry name" value="PROTEIN FRIGIDA-ESSENTIAL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36886:SF8">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="529"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="696"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="846"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="1024"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="1578"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="529"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="696"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="846"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="1024"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="164"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="659"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="723"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="866"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="959"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1054"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="667"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="723"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="756"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="797"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="824"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="876"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="965"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1063"/>
            <end position="1080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1718" mass="188471" checksum="E82A87C7600888AF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLX2</accession>
    <name>A0A9P6JLX2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BTN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_859834</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the battenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157886">
        <property type="protein sequence ID" value="KAF9525288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLX2"/>
    <dbReference type="OrthoDB" id="5965864at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9525288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="503" mass="55204" checksum="BE78169BDFFFC00E" modified="2023-09-13" version="1">MPERATFEPSELPQSLSFPEAEDYFGRQEEEADEVSKKREQGLYRRLATSFFLFGLINNVLYVIILSAALDLVPPSTPKGIILFCNIAPSLVAKVCWPYLLRGRIRYVRRLLGCCLLSTSGMLVVALFNNLPMRLLGISFASFSSGLGELTFLQLSTTYAPPSIAGYAVSYFASGTGAAGLVGAFLWWELRGLGVRLGVGLSCVMPSIIPITYFLLLPHAGSFLNSMAPSTYEDILSPVPDLSTLPYTPLATAEDEDGEEEGSLPAGPKRGISLSLNDKWKLVKPLLAKYMLPLFCVYLFEYTINQGIGPTLLYPVPSSTDHWILSKIIHGVRDYYPLWQLVYQSTVFLSRSSISFGLPALPERLLALPAVLQGMILILLSYESAVGVFGPGDGKNKVEKDTMSIVFVFMLIALEGICGGLAYVNVFYRITHEAPNQHVTVSHTSSMNTNDIEWTRQEREFKIGSIGFADSTGILLASLLSMPTEVELCKAQVARGKMLCKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMF0</accession>
    <name>A0A9P6JMF0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_837480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157873">
        <property type="protein sequence ID" value="KAF9526247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMF0"/>
    <dbReference type="OrthoDB" id="10692442at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="449" mass="52434" checksum="A62467D989191D52" modified="2023-09-13" version="1" fragment="single">SDQEQSDESIQPQLTPSPLLLPPAASTDPLSPLLIQLNLDDDSDSNKIRDPRPADQRMELDVGITEMKDPNDVDLDDDGVDTISEIFDYTQLDQAHQLDYKEVYHIDEPLRLLTNEKGILGYAYGRPVFRTNEPIHLFQLPICSRIYNSTQKLDLDEKWFGDDIATYLDEHMHKPYGIPVPQELLQGATLIGNITFFAPPDLPPLPYEFPKDDFPHPDKPDNFKYIGCLPRYNATIFRRYWRSFDQPICTNIACLRMALQEAENHAINIPFLDVDWENEIYPAAFRILFCFPTPTLYYRYLTQCFPSRVNCIWLKRIPYLFNINRLLASLLHQLENLFRALGFSGLKELLDRTPLWTDLDYQHNPYLSTEEATYLTCAYNFFQRERKRTSSTELLQLLRMDVEDCGGLEWVWAYVVDITYPPHLYYNVRDEKDAEGSMEGEKDEMDWNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMY8</accession>
    <name>A0A9P6JMY8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_857512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157869">
        <property type="protein sequence ID" value="KAF9526621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMY8"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="398" mass="45288" checksum="BA92A2BAA31020E7" modified="2023-09-13" version="1">MWVTGSAGSGKTAIAQTICERFREKGHCVVESSFFRSTNRTNPKYLFLTIAYQLAVANELLKTFIEAVVQSDPAIVDAALDKQLQWLILDPITQAGNQLPTVFVIFDGLDECEGEAEQIHIIHLIQAIIKDQHLPLRFVVASRPEIWINNAFSLPASPALFTVTLNQNAEANDDIRFFYQYEFTKICKNPEHSHLFGSMLTPWPSNAGLNTLVEQASGQFIYAKTVTRFVGEPGHSPWRRLELVLQSHSESKTSVSVYIFSTSISSHVWPTGNAQVAFWVPCLYSTLTAIIREVKHYRRLRFYWIRALVILISLCEIYTLWCLSPPILPLSERRCPLRSTKRSSTIKDNTLDSIINHLWIFYTTLNMQTNTLLTKKRSLLIYVVVFSGMETGEHNEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNF5</accession>
    <name>A0A9P6JNF5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157862">
        <property type="protein sequence ID" value="KAF9527342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNF5"/>
    <dbReference type="OrthoDB" id="3171058at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="59779" checksum="1BBC9E479797F490" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP31</accession>
    <name>A0A9P6JP31_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP31"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF218">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="525" mass="59413" checksum="7408A0B34ED265E7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP87</accession>
    <name>A0A9P6JP87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP87"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="65" mass="6981" checksum="73004A70B9FAC91F" modified="2023-09-13" version="1">MWKTESGGKAARERHQSLAGQTSAATLEGLVKSSLGVWLGSGFFVKQLLLACHMVGFARKREGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ35</accession>
    <name>A0A9P6JQ35_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">snRNA-activating protein of 50kDa MW C terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_906148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAPC3/SRD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ35"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003681">
        <property type="term" value="F:bent DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022042">
        <property type="entry name" value="snRNA-activating_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13421">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13421:SF16">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12251">
        <property type="entry name" value="SNAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9529172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="376" mass="41827" checksum="D585D37E1E4C0385" modified="2023-09-13" version="1">MNPGQAQTLESLFGPPSELIDIGKFVGCALNQDQARDEGERDNVAHEIEDECSVDGIRESLFNVWNNPLLAAHLGKGHDKAVSNFHVSANLTKRTRKAEKSVSSTFSSGVEELQQSLDAVELKAFRLNTDSILFMRTSKNSDYNVLEKKGPVKTSDGAKGSQDVIITLSVYDKVAWAASYVKRSSQMSFCSSQTLEDVYRSIPCLTKEMPSGYDPSTSGCLLYLEGKVYQNEEQDGYSGKLFSHLDSLSKRRPNIIERSNANLHDSTFHSLNIRLREPYWMVHSGNCEHFVVFDQIRLAHIADPLSGYPFFLQVPPALLDLCRGCTKVPAYWSIVGDIRLGESPCVLCDFCWKSMGDSEEENVKVIPVTKPRAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ67</accession>
    <name>A0A9P6JQ67_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ67"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="63" mass="7817" checksum="F56371D419DEBEAB" modified="2023-09-13" version="1" fragment="single">MATLLRRLPFKLSDRLFTHSSSEVPWLDRYSTLVAWRYANIWSNFFYLASWSVTLYFLRHWWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQP0</accession>
    <name>A0A9P6JQP0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_875348</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQP0"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="9">
        <location>
            <begin position="49"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="197"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9529877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="600" mass="64684" checksum="45CE9CAE81726EF7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRB3</accession>
    <name>A0A9P6JRB3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Iron-sulfur cluster biogenesis chaperone, mitochondrial</fullName>
            <ecNumber evidence="3">3.6.4.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_893247</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Assisted by the DnaJ-like co-chaperone jac1 and the nucleotide exchange factor mge1, it mediates ATP-dependent Fe-S cluster transfer from the scaffold proteins isu1/isu2 to grx5.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="3"/>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRB3"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000020">
        <property type="entry name" value="Chaperone protein HscA homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000005">
        <property type="entry name" value="Heat shock protein ssb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000007">
        <property type="entry name" value="Heat shock protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="644"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00059314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00070638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9529728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="666" mass="71873" checksum="FC8EFA97E5185C6F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRT4</accession>
    <name>A0A9P6JRT4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRT4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040197404" evidence="1">
        <location>
            <begin position="21"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="176" mass="19540" checksum="B06EF55F20B02F61" modified="2023-09-13" version="1">MQLLIKIVSVALILLHTSNAGDICAYTTDGCGGLAGCCNHFASGECCAFASGYGLSAHWFNIDRSANPNLEAYIYSSTTCGNYLNQIGNVGASGITTCYNLWGKVAHSGDWWTSRLDRRLSRRESDCKEFDSIGFRDSNGTFHEFKVPNGKGFRDIEKLVKEEEFEQVFALERVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSX4</accession>
    <name>A0A9P6JSX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_904808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSX4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="529" mass="60880" checksum="7C1F682A800D04C1" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JT33</accession>
    <name>A0A9P6JT33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_849006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JT33"/>
    <dbReference type="OrthoDB" id="5362978at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="179" mass="20573" checksum="D6D6C124EFB2A0FC" modified="2023-09-13" version="1">MPWPLPIIRQFAKIPVNPTEADFHGVYNKLLYTLFPADSAFTVAPQFMPASPESAECDFYFDVMHEDRIVFIVHLRSPGDIRYVSKRELADKQIRNRIRDLLDDCPIPVLHAISAIGTQLCFFTKRINERVNPLAIPPDNTYENDTAPRERWNYNVLEEAGVQKLRDVVEEIKEACAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTA0</accession>
    <name>A0A9P6JTA0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_760326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9532126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTA0"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376:SF235">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9532126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="289" mass="33287" checksum="CFCBD60C264AA59E" modified="2023-09-13" version="1">MPYCQRCNIGFGSHRALAQHEQDSNNHHICNQCDIDFSTWAGLKEHWVQSPYHVYCQYCNEHYDHLDDIEEHYEEYHHYCSACRCVFRNDVGLREHYRQSKRHHYCISCDRHFQSASNLDAHLNSSVHRQKTVMCRLGCGKTFVTNSAMLLHLEGGTCSSGMTRSTVNQFVRQYDTSNFITDPSRLLTGASETQITHIASDAAWNGRAFECYLCHSQHPSLKGLNQHLSSPKHEDQIYVCPGPSCRTRFSTLSGLVQHIESERCDVLKFKVVQRGMESLFGTMGRLGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTD8</accession>
    <name>A0A9P6JTD8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_847508</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTD8"/>
    <dbReference type="OrthoDB" id="421393at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009449">
        <property type="entry name" value="DNA_primase_large_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="11">
        <location>
            <begin position="287"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR009449-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9532246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="484" mass="55884" checksum="7CD774ECF68A6849" modified="2023-09-13" version="1">MFKGGQTTSPDVSLPHVTNSHLLSYPNTLNFYERPPLFDVTVEEFETCALDRLRILAEIESSLARNRNWDELSTVTKTQCDKYLPLNSHRSIRFTDLEAERKKDHLSHFVLRLAFCRSEDLRRRFVKSETLLFKVRYEIALTEDREAFLGSRDFNWTIVPSQEQTQLKEDLERAFIGSKSEFERTKYYKVKWTRVPDLVEKRKVFLKGGWAYVPTKEQSSIVFHEFESHLEKTLETTARLLPRLDEDTRLLPILNNISQGFLAGVSSEWAGASGSDNADEIKAEMIDEIARRSFPLCMRMHHEKLRKDKHLKHFGRLEYGLFLKVLGLSIEEAIVFWRKSFSRIEDDKFNKEYKYNIRHSYGLEGKRANYPARSCIQLLAPGSSEHGCPYRNFDEDNLPTTLISVYGPQGLRSSDIREVTDTVKGKHYHVACTRVFELTHASCGVNKGDGIGGGESVTHPNQYAARSMELRKPKESKDAMQVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTZ8</accession>
    <name>A0A9P6JTZ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6532 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_890138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTZ8"/>
    <dbReference type="OrthoDB" id="3055188at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045341">
        <property type="entry name" value="DUF6532"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20149">
        <property type="entry name" value="DUF6532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6532" evidence="2">
        <location>
            <begin position="133"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="380" mass="43609" checksum="1C5E3AA2B3B4F299" modified="2023-09-13" version="1">MLDTPLALGTPRQYPVRERVKTRSKENSIPHPYNARKRSARQVSPSRSHSNYICKPLLSTQAGACPKDKRKHGSISNEETLTHNNTLAIRRIRKLTSDDNTINVTAGYSDSPSDEEPEQDIDSNLRECIVNCAKLYFQEYLALRNFIPDVNKDLHEALACLLKSIDLWNLGGEQLQINERVTREMSLEVFEEAAVYLQRLNDHCVKLVIVHYCDAIHPQELTEGQHELTCLIIDKIEALVGPDLHFHLGEVDDQGKHSNMMHPCIHQVCIDFFYKSEQSPLARRLPEVFQDCVLEHAVAAVATCVCHALEEYSFGKHFNKEFPSSSDRSIYEGILESIAMIKTNPYHKDKWDQCCREWAQDGMDTDIPRMEKRVFKVYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU09</accession>
    <name>A0A9P6JU09_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_867661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU09"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="265" mass="29283" checksum="D3C50AB1BC521EDB" modified="2023-09-13" version="1">MSRSYDRALTVFSPDGHLFQVEYALEAVRKGTCAVGVRGKDVVVLGVEKKSVLQLQDPRTVRKVVMLDDHVCLAFAGLTADGRVLIDKARIECQSHRLTVEDPVTVEYITRHIAGIQQRYTQSGGVRPFGISTLIVGFDPHDTKPRLYQTEPSGIYSAWKANAIGRSSKTVREFLEKNHKDDMTRDESVKLTVKSLLEVVQTGAKNIEIGVMESYGKVTNLEPSEIEAIVAEIEREKEAEAERKRSRLAATAAGQAAMGQRAGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUR6</accession>
    <name>A0A9P6JUR6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc knuckle-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_845832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUR6"/>
    <dbReference type="OrthoDB" id="437973at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="115"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="177" mass="19432" checksum="8E401D6CFD14714F" modified="2023-09-13" version="1">MSRFAPHGGRFSQPRATSSTICQKCLKTGHYTYECKSTRPYVSRPSRTQQLENPKIREKMKASLEVPDEFKKPAGTANRILEDKEKDRAKGDKPKNKGKEKEEGESRKRRRHSRSVPSSSGSSSDSNTSSSSDSSSDSDSSSGSGSSDSGSSRSGSRGPKRRRRGNSSESLRRGRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVA3</accession>
    <name>A0A9P6JVA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_407837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVA3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9533763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="46936" checksum="8D79B93D86BA6FEF" modified="2023-09-13" version="1">MSTSRPHFMDPKDPLPIPQGARDVDMKDELEFATFAEQDSEMDIDHAQVAEPMEGIAVGVASIEGLGEISMTSTASREVASVEDSQMDTSVFLECINAIRPAGYSARLKRTVDTAFEPTERAVKSRLMDDIYGEIEYTYPREDTLPAEPESRPRPHPSHRNSGIHSCNQRGGQYVAFIGTGTRDICHWQACTYEDKKWCRRVMKSLCLRGRVRQCPFRVMHEGKHIVDNADAPVSRPALLDVESNPLIAKRVPSVPIFDINRIATFATLVKLSTGDVNMDVPVAPIEFNLHLPQRYNLLAKFEEKDLYPDLLQPVDEKKAAKRETKAAQVVKAKKNNAVKQKIGLCVGKKGARRRTGSSRSTTKSLSVSQLSCRGSKNLWFPFLPLVGLRIFPCYLFLFAFITSRYISRVIYPMRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVE0</accession>
    <name>A0A9P6JVE0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit J</fullName>
            <shortName evidence="4">eIF3j</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 30 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF-3 30 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HCR1</name>
        <name evidence="6" type="ORF">CPB83DRAFT_844680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit J family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVE0"/>
    <dbReference type="OrthoDB" id="20381at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03009">
        <property type="entry name" value="eIF3j"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9533883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="264" mass="29109" checksum="CB4FA267253C6C03" modified="2023-09-13" version="1">MSDDWEESSSEEEKQVKGKPSAPVVKAAPPVKKAPVVNKWKDEEEEEAPASDWEESSDEESEDEKPVVAAPKKKGTLKQKLAEKEAAAKTAQANGDDDEYDSDAVLEPREKARRDRERELRADMTNAADLLGAGALGGTSSSELDRLISFQPRTKEDFVTFSDQIIEFLIKKHESKPLYHAFVEHHVRALAAPLKDVEVRKAASGLTTLANEKQREQRDKASGKKKPKAATKPVLGSAKVSSKLDTGVYDEALDDFGKEADDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWU7</accession>
    <name>A0A9P6JWU7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_888971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWU7"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040317817" evidence="3">
        <location>
            <begin position="23"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="305" mass="33794" checksum="C291180E5AB78807" modified="2023-09-13" version="1">MPRLSRLLAATTLLASGTLVHSHPASQEVARQLPATGPNYRFSFGDSYSETRFNPNGTLPNPANPLGNPDAPPSGPNWVTYGTTKYNHSVVYTYNYASNGATIDDDLVEPSDPSSRTLTDQVNDFLAGAGKKPSATPWTSENSLFSIWIGMFDIEYTYFLSGNRDLFSDQLLDAEFPLVKKLYDAGARNFLFNNVAPINRTPRMLRQPSSAQAKQAEVIDGFNARLSSWIRDFGSKHTDAKIFFFDANARFTSILNNPKTYGFKDAKSYGSGDDFFWMNDFQPGSRANDYIAQVVGKDVLGNTVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BC97</accession>
    <name>A0A9P6BC97_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_928288</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="MU158078">
        <property type="protein sequence ID" value="KAF9521405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BC97"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="6">
        <location>
            <begin position="6"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="8">
        <location>
            <begin position="158"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="7">
        <location>
            <begin position="336"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9521405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="506" mass="56896" checksum="36AD5AA8F50B80F6" modified="2023-09-13" version="1">MNTQSQDCFLDWNQVQNILLWVPEWDGTFPTPAIIKPKPLWTGKQILSMAIPRGINIFWSPNPKSSSPVFDDGVLIENGELIFGIIEKKTGSFTSYSAEKGPEATRQLFTGLQMVVNYWLFHNGFSIGIGNTIADQKTMSFITQTIAARKGDVAKIIDDATHNRLKASPGMTIRESFGSKVERELNLARDKSGKHAQEHLKEDNNVKRMVVAGSKGSFINISQMSVCVGQQSVEGRRIPFGFKHQTLPHFTKDDFSPESRGFAENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIRRRLVKALEDVMVCYDGTVRNSLEDLVQWVYGEDGMDSAFIEKQTIKTLHNYRVDVTDPAGGFLPGILQLGVDHSSLDLQVKLDEEFGRLVEDRRLLRDFIFPRVSTNQPITSPSTFIAFQKPSDLEPAYIVDKVDELGKRLVVVRGDDPLSQEAQDNATLNFRMHTCATLATRRVLEKFHLTKEAFDWVVGEIETKFNQSVAHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2M0</accession>
    <name>A0A9P6E2M0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_911795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158194">
        <property type="protein sequence ID" value="KAF9521258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2M0"/>
    <dbReference type="OrthoDB" id="412109at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="415" mass="48125" checksum="857CBA0CD9C81BB7" modified="2023-09-13" version="1">MMNDANERAGVAAQTRAEELSRSLGIYMHERRLLQEVSIRLQVENNELLATRKTESERQEYLTNAAHAAWVEAECRAQEAARTSGNAIRQKEMLQQKLYVIQESQAKELAGMEDEVKRQVEMRENAFRQQEMLQQKFDNIQEMRAKELAGLEDEVKRQAAMREAAERALAATEIRAAEAYQTAAILVQEKQALETMVTNLYAERDASFQRELDWQFRLMTALRRVEELEVQGRFLEELYHLQNIQLQEYQRVFSQQRKENTSGNDPGEDIPMKDSRSAPTPPPAFPQSPPPSPTPASFEPPPVPTTLRGWFLSYEQRWEALQRNDCRYNLTFAHIPWPVSRFVARLEDLDEEEIKAFLTKKDQIVGIQWRDEVKRWHTDRFARVAARIHPAARNDVLTGFNRCIQIVTLLRAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E354</accession>
    <name>A0A9P6E354_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158006">
        <property type="protein sequence ID" value="KAF9521654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E354"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="127" mass="13956" checksum="AE7FD095F007CC73" modified="2023-09-13" version="1">MALPWLSPLDLGLPIGQPNPVVNLFDPPSLNVTTETNECTHTICIFGSQVLRAISKFYGDEHIAPTATQTARFNGLKIPVAEYKNLSAGEIDDVKAFYGQFEVENLAQIVEKQTRDIQALLGKPSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3P3</accession>
    <name>A0A9P6E3P3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157970">
        <property type="protein sequence ID" value="KAF9521966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3P3"/>
    <dbReference type="OrthoDB" id="2104739at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40040" checksum="CC91D6DEA8258ACF" modified="2023-09-13" version="1">MIIEAPTERGRQNFSSEVLRCQQDDDALQELAELYKDYFIRVFYSGKGCTPVPRSHPTAPFFDVTKTQKAVPLQATPASHAKAKQSALKRDGHSISRRQSGVPKSVCSKTLTCAGHIFDRSTLENVTDDEKNYAASVVAVLERFGQINVVQELNEAQVHRLENILTLSMEVHEWFDKLFLWLEKDPNNPPNTYRPKSTNPELFLDDIPLVVTLSTPNLDESPLPHPRYLAVCAACAKVEYVNEILCDMEEIGTLASDGSSNALYQVLRLHADVEFLDIIPRRSQLLSSPSDLNLINSPRMEDPHEHLLQSMVYAESNFDLGLNIPNDEEVECEEFEASEEVKGAFGSHTPHEFEVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3Z9</accession>
    <name>A0A9P6E3Z9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3Z9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="34196" checksum="2F820BAE166580C3" modified="2023-09-13" version="1">MKISTTALVCIIVIVTITTILLRQFFDGACYLDFIGNETCACYDAEGTPFGSLEVDGGAQRSNAGLESARAADIEVLKASITTLNNTIEVLKLEMQARELRSTNNLNYSFRHCNLIETDINTIAAPVYNYGTWQWDQPKTLMASSTLQVPDLTMDVTAAHTTDSEVMHEASVDLQALLLVQEELASLQVSHINTPSHINDSSTVIPATHATHSLCHTPIFFLSFSELAQMILQHLGGGSSSDSANHSRGVAYLGSTTNASATFGYNDIQQNPCLETSRSIVFPIAADNTTDCLAVDDERDVNCSMPLTFKVPTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4A1</accession>
    <name>A0A9P6E4A1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_872051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NOSIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157954">
        <property type="protein sequence ID" value="KAF9522237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4A1"/>
    <dbReference type="OrthoDB" id="116827at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031790">
        <property type="entry name" value="Znf-NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15906">
        <property type="entry name" value="zf-NOSIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023577">
        <property type="entry name" value="ENOS_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="270"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR023577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9522237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="347" mass="38043" checksum="34DC548FB9173811" modified="2023-09-13" version="1">MTKHSKNNTASSIFSYAEYKKLDYGTKRQRLGNESMRRFDACALCLNRAREPLACTEGHLFCKECVYTDLLTQKKDIKRQKDRLDALKKEAEVEQAKAREAARERVLREFEKGQLGLASGTVGSRIVEKKANEPRGTKRKTPPPLEPSTPSEAFSFSSKAVHDLADKAEEAALKQIESELTESLKAKLPDFWLPSLTPTHASNALPQNLAEIDAGVRKLQTVCRAGQESHAVALKNLVRVNFTMYSSSSNPSGSGTSEGASKKEDSEAMCPSCKKNLSNSSLMFLSKPCGHVTCKTCTDTLVRPSKQCIVCDTKLKEKEIIELKREGTGFAGGGLAETSKTGIAFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E511</accession>
    <name>A0A9P6E511_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_864163</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Secreted</location>
            <location evidence="1 7">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the fungal hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157939">
        <property type="protein sequence ID" value="KAF9522615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E511"/>
    <dbReference type="OrthoDB" id="4225815at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23507">
        <property type="entry name" value="hydrophobin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001338">
        <property type="entry name" value="Class_I_Hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019778">
        <property type="entry name" value="Class_I_Hydrophobin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01185">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00075">
        <property type="entry name" value="HYDRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00956">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040527991" description="Hydrophobin" evidence="7">
        <location>
            <begin position="19"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9522615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="105" mass="10298" checksum="B9A86A552F582E0F" modified="2023-09-13" version="1">MQFKSLAVIALGASLAAATAIPASQCNTGPVQCCNSTGTAKDPSISKLLGLLNINVSDVDAIIGVTCTPISVIGVGGNSCTAQPVCCSNNSFNGVVAIGCTPVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5I9</accession>
    <name>A0A9P6E5I9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5I9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="232" mass="25574" checksum="773277E43DA89334" modified="2023-09-13" version="1">MSLPPSFDKKLQFLVDSKQHKYRLWQQENNANVKSHTSSAPPESCYSSLAGMELGDPHSSTPSISIMASSTACTTPDHSIGGSVSSLRHVHPSLSDQLSIDSSPFGALYQPLRNPLQSFFSTILGVQNLPECSHSYYHTPMHPKSSANPFQSTLYLCTNTMVVEQDAGRYCAALYIIVPRADSLSSSVALGEHRTSSILRKGDRVVFNGFTSRFTYEITGGAVFLVEWTWYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5S1</accession>
    <name>A0A9P6E5S1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157930">
        <property type="protein sequence ID" value="KAF9522924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5S1"/>
    <dbReference type="OrthoDB" id="2923771at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027948">
        <property type="entry name" value="DUF4436"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14494">
        <property type="entry name" value="DUF4436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38536" checksum="721E7EADC3D0D32D" modified="2023-09-13" version="1">MFQRFVCLSIWLMTVAVVIFLVVARCLVPHPVSFSAPDAFSNNAELSLAIELISADPVARTITMDWYPLPFGRSCTIKPGKVIDIYVDPNILDSSSLRFTSTVLSVALADYLPVQRINFTAYCQQEISVLLAFRTISKLLNSDKTAGFPGTASRSVENYPFDIYFAPMYVYALDAETREYVKLNVSHSFGQIVNFAVDLHDSREWAHWLGFSLRLKRSTATIVFVLAAALNNWLLAIAFLTICVSAVVYPSHQIYAEMFVVPVGAVFAFTAIRVGFPGAPSGFGASIDIYTILPVLIIMSFCSFFLLLIVLYRRIEVFGPAEGVVRAQSSTKSMREKLIDYWFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5Y8</accession>
    <name>A0A9P6E5Y8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_887226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5Y8"/>
    <dbReference type="OrthoDB" id="3014077at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="77"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="445" mass="49791" checksum="05FAF60154040AFD" modified="2023-09-13" version="1" fragment="single">MSRQSIFRNAQNCSVTNSPINIHNHDSRSSGIHLLSQQISTSAMHDSSARDPPPRCHPDTREAALDTIDAFVEDPEPDKAVMWMNAPFGHGKSAVMQTVIENLRVSGRGHRVAGGFFFGRDKEGRDKAHYLLPTILYQIAENIPEMHERINKVINANPTLPSKSIQAQLIPLLVTPFQHYTPSSTHTPTVFIDGLDECDTPTAQRSVLKMIADAVSVHHIPLRFVVASRPEVHIGQCFKAPPLSSITRSFELDDDFLSMDNYFRDEFDKIYASRPDEMSAIAQPWPSNEVVWGFVQRASGQYLFASTIIRFIGDEYENPIQQLQSLFSPLPHQHSAFSSMDALYTQILSVCPNRLQVHLVNILGMIIICAEFATIASVSDLLGLLPSDVSTAIRGLRSIIEIKNLPTTLLHDNHNTDFALLTYLSPYVSIRHLSLREFLTDKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6I1</accession>
    <name>A0A9P6E6I1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_839689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157917">
        <property type="protein sequence ID" value="KAF9523446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6I1"/>
    <dbReference type="OrthoDB" id="3270336at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="35806" checksum="49C8D8A98E75BA79" modified="2023-09-13" version="1">MPYHRTRHGYRADVRTILQWGKLETEIRHLTKQLATKYDVPLGRDIMGDENAVVCSAAYLSPEEFKKQLHRTQGWFSVHMARLSWIIAIALASDKENPLTKCPQWMSYLLERSQPEPLLVHSIRSSAAAFSHYEPFVGVFVNILKFNLSHPSLQFLIRNKVPVWYRWTSAEEVEASSSPFLQRYAPLTEQYQQASTTLIANPTPPHLDNISLPYRPDYSDALPGTEDAPSSISSGPGISLAPAEGPSLQKTPDEPWVDLRYDAFFNVWDFCSAWREKTAEEIEADEEDDEARSSVSLTSLFVRVKSQSSTIIFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E6U2</accession>
    <name>A0A9P6E6U2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_691315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E6U2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="187" mass="20917" checksum="DFE5808E7B264775" modified="2023-09-13" version="1">MSPHGVGTPEDKGPPPGVKEFEKIKTVICVCETIQRLTKDITELKTSDKSLNSDLPFTQQATNQILNMIWALPSKSLPSVSHHIYLYHRILVDLHERQQESTHINFAKDFHEPINNIVEGLKKEIFALSSSPQSSSTQNDSLTGLNSMGIFNHSQQVTMSNVSFQMTQNTIDPKPSQEQSVSRLSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7E9</accession>
    <name>A0A9P6E7E9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conjugated polyketone reductase C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_949659</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157911">
        <property type="protein sequence ID" value="KAF9523734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7E9"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9523734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="308" mass="34007" checksum="CF1F28E40665DB22" modified="2023-09-13" version="1">MTIQSSVTFKLLDDTTIPWIAWGNGTGDAKVKALDCGRAALESGIRHIDTAQIYHTEKETGESVKQSSLKREDIYVTSKLSSHDDGSSRSLDEVVPAIQESVDKLGSVPDLFLVHNPYVAKPGELKSLWKILEDLKDQGQLKSIGVSNFRPQDLEIILEGAKHKPVVNQLEYHPYTLAHLQPILDIQAKHGIVTESYGALTPLLRHPTGGPLKPVLERISARISKVHGKTIDPTVVLLLWTRAMGVVAVTASGNIERIKKMGEIATLPDLLTEEEIKEISEVGKKVHFRHYTEHMENDFALPDLPNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7N0</accession>
    <name>A0A9P6E7N0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_862205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157909">
        <property type="protein sequence ID" value="KAF9523854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7N0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040262084" evidence="1">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="190" mass="21972" checksum="4C2589BD70F6D432" modified="2023-09-13" version="1" fragment="single">MFHIWRLGSIYTLLCRFFINCHRISLWAVCNAGTSSFRITSSFRIKMISTSYGDKLVESLSVPSRYTLEMRIKPRPRKMKLTQQTLRTCIRYSSPIGNITILWRKNRGCDHADNFKLAHGKGYHLSANDDIHPPSHLKFLSFGYSPSRPSTPLSNWKLVESRRRSCLRNFVHPHDVLSTVINLTFLNDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7R6</accession>
    <name>A0A9P6E7R6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_949051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157907">
        <property type="protein sequence ID" value="KAF9523948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7R6"/>
    <dbReference type="OrthoDB" id="2654453at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9523948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="291" mass="32020" checksum="F00EA0725A0CF4D6" modified="2023-09-13" version="1">MYCPGTDGVKVWNLSTGKEIPTPQQPLQERGQVSCVYWITRRNEPFDTLCYGNALGYLVFLQHRPTEQQFESVCSACIAQGGEILSMTAEDLGGGSTRIATGTRDKCVQVWTLDSSARKLLSVHSSAFSQEKDIIPKSLAFDGNESKDLCVFGLYNGGLCTFETGRMLHVTDFLCRGNAAINSNHRLCVIDNVGNGFDLYKLDTSNFVRTFVTKEPIKTYPKGVAFAHRGHAVVGGSDHGCVYIFDRRSGNVLHMLKHAQDGGVQTIAVCKYVPEYHKFADAEARSTTAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E7X8</accession>
    <name>A0A9P6E7X8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_645205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157906">
        <property type="protein sequence ID" value="KAF9524038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E7X8"/>
    <dbReference type="OrthoDB" id="4760524at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="41"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="574" mass="65833" checksum="C69352FDDEA7179C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E826</accession>
    <name>A0A9P6E826_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_861289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E826"/>
    <dbReference type="OrthoDB" id="3062963at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="299" mass="31603" checksum="0F342A01A712812A" modified="2023-09-13" version="1">MDSPTLVAPMSSTYSAFFASGLLAPRTPLPKLQRRNTYQSGISEPWDDDAEFSSSSSYPSSPLRSPNDESLMDLDIPEFLDTSVHDSRRSVTPTPESERATPVPSPQGAKGDSRPRLRRRRSSLTQSVSPMNAIRSPSRTAGNAFHLQKQLAGTAVRNRPASLGGEALALYGTLGIGMAGMPTNETSLVGRMRSGSCSSANPQTAGTGLRPAFRPRRAARRILTLPIPAAAPPPTAPLPALPSLPPTLRSTNLNMSGPASAPLPPPGGKTSSARARGLSVSNSAMNGAEHRIDEEMKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E878</accession>
    <name>A0A9P6E878_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_618711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E878"/>
    <dbReference type="OrthoDB" id="3270987at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="62"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="498" mass="56697" checksum="C0E44B33B3CBCF58" modified="2023-09-13" version="1" fragment="single">MTTGSFNLNKAHGCSHMVESISCSRCVWGNTADDIQPMGNFHHLVQLREQHPENVDICNPFIWRLPVEVTSHIFSLCIIPTPLIDDFATLIYDFEGISNQVLLFQLTLRAVCRSWYYIASSNKMLWTSFSINLTPRSVVGVGKLAEEWLDRSGELPLVIRLLYNGRVSLYDGQIQRSELDGTGFSKPLLNAICTVSHRWDMVAFKLPNIFMQDLRCDVRRPPSCLRSLVLADSLEDPTTSGVLNLGFIPSPVRLRLDLPLEQVRLRWDKLTHFHATHFINIEAVVDILYFAPSLLYFCPTGLEFDLRNQNIIRHPNLQHLDIQNCFSTILDLFSFPALRELSVEGFHLEYDAGINFINRSQCRLHNLSIDGLGCLSTEELIVFLTSTPSLRLLELDHIELDSTFFDRFAESSNFLPNLSILSLDFDDPEFLRTFFRLLIPSTTSRSRPLLKIILRHEVDLGEEANSSGSEIATLGETNIRMIQDIRKSGVDFNFSTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E9C6</accession>
    <name>A0A9P6E9C6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L14 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_897481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157891">
        <property type="protein sequence ID" value="KAF9524946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E9C6"/>
    <dbReference type="OrthoDB" id="407959at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9524946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="139" mass="14687" checksum="DD1BEF2E5CC4D43E" modified="2023-09-13" version="1">MAARGGGAAGSKFRMTLGLPVGAVINCADNSGAKSLFLIEPFGFGARLNRLPDAGVGDMVVASVKKGKPELRKKTMPAVVIRQRKSWRRRDGVFLYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASNAGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA01</accession>
    <name>A0A9P6EA01_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_859376</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06627">
        <property type="entry name" value="STKc_Cdc7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000583">
        <property type="entry name" value="MAP3K epsilon protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000946">
        <property type="entry name" value="Probable serine/threonine-protein kinase DDB_G0284251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361:SF433">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="278"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="559"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1236"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1239"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1275"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1336"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1363"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1389"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9525506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1405" mass="151564" checksum="78E900FF5D847375" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAN8</accession>
    <name>A0A9P6EAN8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_909044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAN8"/>
    <dbReference type="OrthoDB" id="3270520at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="371" mass="40826" checksum="FCAAE99165D5BBE0" modified="2023-09-13" version="1">MTALRFEDLHIGQAIMIDIWKISSGLWNPSSPEGSLSIKTKAGSSPWLGVVARVEQGTSETIFEVAQKTDEGRIGLRSRYTGKLLTHRGDWAYADGDTYSAFFGQEITVIDGKQVYKLVTQTRLPSTPSMRLILDINSVLTRSSCATNSVSTAGRIGFVKLAICILRMVPNSASTECTFSSFGVIHTKRRNRLNAQKVHKQVMVHDNIMQAYQEAGVLPIRKKLKFGAEEPITVATTLPDASTDTDSESSLTQPNDFRSVASILVAAASDGSANDENKNENENEDHDNDDVVSVSAPRVTQTSHTSASTYMATRHTSAHRRPTNLPHPFFITLANLFDYSTEVEEDSGLAFQWNVAQSWHEDEGLSDDDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAP3</accession>
    <name>A0A9P6EAP3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_859264</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAP3"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000014">
        <property type="entry name" value="D-lactate dehydrogenase (Cytochrome), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="11">
        <location>
            <begin position="133"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="566" mass="61195" checksum="193431844D8A048A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAW2</accession>
    <name>A0A9P6EAW2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RecQ-mediated genome instability protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_795942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157881">
        <property type="protein sequence ID" value="KAF9525640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAW2"/>
    <dbReference type="OrthoDB" id="341511at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049363">
        <property type="entry name" value="RMI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790:SF15">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21000">
        <property type="entry name" value="RMI1_N_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01161">
        <property type="entry name" value="DUF1767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RMI1 N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="4">
        <location>
            <begin position="77"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="533" mass="57942" checksum="E05C0BEAC6029D3D" modified="2023-09-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBN2</accession>
    <name>A0A9P6EBN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_858784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBN2"/>
    <dbReference type="OrthoDB" id="3227768at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040534980" description="Extracellular metalloproteinase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9525879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="606" mass="66480" checksum="E50A3627D229EA02" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBW3</accession>
    <name>A0A9P6EBW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_495904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBW3"/>
    <dbReference type="OrthoDB" id="2505473at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="247" mass="27407" checksum="243F714AA33CB962" modified="2023-09-13" version="1">MSTPSTDSSTSSSNRGRGRGKSRGGLGKYLRARGRGRGGRPAEFSQRLLLEGEGRSHLTEEEAAEAEKELREKYGRRNLGTNADRYKEEEPELDSDGEPIVEPEVDLSTFLEKQKISDDVGPTISVPAVDLAYNEDDVDESLSHITSDPSKRAVQSASRKGKVQQIEWDENLEELSREKRASEATKDLKDRFKAKSEKLKAKPLTPTSLSTRRHQGTLEEAPALPVPGAEPRSQIEEMEDFLDELIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECA8</accession>
    <name>A0A9P6ECA8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_857789</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECA8"/>
    <dbReference type="OrthoDB" id="2410195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="5">
        <location>
            <begin position="95"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="241"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="460" mass="50285" checksum="E7CE0B599C01EDC7" modified="2023-09-13" version="1">MSLSELTSLQNTLNAAIDTFKAELAAQNLSEPSLNTSKAHPIDDIAYLPTPAMYEARRAALASLGLIKSLIQSPYDALAANTWMVLEVAGVRLTAEIGLATLLGDSEEGMSLADIAAKTSVDGLKLERVIRLLITQGWFREAKPGYFANNRLSNLIKKDLPGFALATYMNDLFNKISASFSEMVNHPDPEFRKNNDPFHTAFQLAFKTNISYFGADGWLTKDPEEAIKFGLSMGAVGPTSDPGVIADFAWDALAQGKDAIVDVGGGQGTLCCSLAARYPNIKKFVVQDLPETRDAAEAHIASRNLQGRVEFEAQDFFKPQQRKGKYLFVMQRVLHDWSTEAGAKMIKHIKDVLNEDSCLLIIDTVIQPAVVSSEGTELNKALQSLNKNVYQPVSPPPFVPVDFGEASRIQHQINVALTALCNSFERTLPQLTEMVELGGMKIKKVHATRGWASITEVVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDT3</accession>
    <name>A0A9P6EDT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_856076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDT3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="67" mass="7619" checksum="94FBD2C6FAB18891" modified="2023-09-13" version="1">MFTLLVIFRTESVCGTIDCILNFILFVIFEGLVIPQPVFNRGPVLSMHHSSQKVESRAFGDTKQDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EE64</accession>
    <name>A0A9P6EE64_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EE64"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="234" mass="26198" checksum="586D1EB35C36E07A" modified="2023-09-13" version="1">MSSRRGKAQEPAFYVHATPYQRGREPRIFDSKSSESEGTFNVLELDGYSGNLVTRPVKSNRGRQKRTPRGLYQQDSRSIRLNGWGITASSSSGSVTTPDFPLPPLPDGLSVMEDLPTCDSSNNSSSARIDFRLVLSRSPSVVSSYDAILESESELPTRPSSVIQPQIDPALLEESKPHFSAKSSKKVFQYSHRLLQPIPVHVAPPYLSYLAYEASVYRNPYQLRPLDPSRRDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEJ5</accession>
    <name>A0A9P6EEJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_856040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEJ5"/>
    <dbReference type="OrthoDB" id="3040100at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9527579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="45296" checksum="C463CECBC7B7E689" modified="2023-09-13" version="1">MPLKYAEDVASEIWENCWALAERDDLPALSLTCHLFNDICKPKLFQRLTFSLPSPRSRSFRGAAPTIGVIKRRYEVISNNHGLSNLIRLLSFGPRSISSMPVVNLPSSLAREEQLRMATAEYNSLLDIISSSISRFSRLQQIFVGPIPLGVKLMENLRPLKHLYKIHLATTSGINVPNGTPPLQVREFSYHEHTLNRNSATPIIAELPAIVASEHLQRLSISGIHAYVIIYSFILHRRIFESLRFLSVSVKPSDISLFFDFLLTCPALEKLHITNYHDLSHVASADLPPIPISAAPRLTDYTGPDAIAVALAPGRPMSMMALVNVASATYELTTADYTSLGRSSPPMTSLNLGLRYMNRTAFHDLARYLPHLQKLTVHIEETDDSEFTPEDAILYLDLLSLGAEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFG4</accession>
    <name>A0A9P6EFG4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pyranose dehydrogenase (acceptor)</fullName>
            <ecNumber evidence="5">1.1.99.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">CPB83DRAFT_792222</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O(2) as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a pyranoside + acceptor = a pyranosid-3,4-diulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a pyranoside + acceptor = a pyranosid-3-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>pyranose + acceptor = pyranos-2,3-diulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>pyranose + acceptor = pyranos-2-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>pyranose + acceptor = pyranos-3-ulose + reduced acceptor.</text>
            <dbReference type="EC" id="1.1.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.29" evidence="5"/>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFG4"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033718">
        <property type="term" value="F:pyranose dehydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19 20" id="KW-0274">FAD</keyword>
    <keyword evidence="7 20" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 21" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="21">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040204648" description="pyranose dehydrogenase (acceptor)" evidence="21">
        <location>
            <begin position="19"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="22">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="23">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="569"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00034059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAF9527980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="588" mass="63612" checksum="4AF70F8EB8595582" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFW3</accession>
    <name>A0A9P6EFW3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mak10 subunit, NatC N-terminal acetyltransferase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_854632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157854">
        <property type="protein sequence ID" value="KAF9528205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFW3"/>
    <dbReference type="OrthoDB" id="269405at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="596"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like N-terminal" evidence="5">
        <location>
            <begin position="40"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="6">
        <location>
            <begin position="396"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9528205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="773" mass="87240" checksum="69E5D854FE8C7C6E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGP6</accession>
    <name>A0A9P6EGP6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_853673</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGP6"/>
    <dbReference type="OrthoDB" id="3229610at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="31"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="303"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9528742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="346" mass="38541" checksum="82731C241CD8F472" modified="2023-09-13" version="1">MLKEGLLPSGWDNATIGVTILFSLAIMATVARLGYRWHRQQLYWDDFWALMALLTAIMTMIIMIVESLIPLSAMSLRSQSFIFWGNFLSHPLELWTSRISIAVTMVRILPPGPKRTITKGSCVVMGFMGVTVIVQKIWITGKPAPLIPKMPFTPLTAILSLSLNIVSDVFLVTWPAFILSKMKLLKSHTRLLIACFSTSFCVMIIDIIQSVRFIQGDIGNAGLDAYILIALSLLLCNTTVLVTCFYRQVMTETSIGIRIPRASHSSYTTNPRFDSTPERSALDPSALVNSTAVSKVSEVGIYPNDDDQLSGKTKTSNKHHSLPPFMIEKESQAYNTYPPGKKGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGQ0</accession>
    <name>A0A9P6EGQ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/calcium exchanger membrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_304938</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGQ0"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="338"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9528625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="530" mass="58919" checksum="22DD7173798DEDF2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGX1</accession>
    <name>A0A9P6EGX1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGX1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="77" mass="8960" checksum="21FFA8B981D706E3" modified="2023-09-13" version="1">MQQIVVYTTREFERALMLFQVLLPVPLWWILSCLVRQTRGNPPSTTLSCGTHAQEEPFPLTYSDRTQASQRRTGMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH30</accession>
    <name>A0A9P6EH30_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_869382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157851">
        <property type="protein sequence ID" value="KAF9528594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH30"/>
    <dbReference type="OrthoDB" id="3226344at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="399" mass="42821" checksum="859B888F544EA323" modified="2023-09-13" version="1">MMLYQKPSPINMSSPAQFSHRRHPSAPVVVVQPTRTPGLLSLSKPVRPTPPRQQPQQKQHNLRPSPKNHTKPTQGVVRAQALTPPAEIVEKSSVAYAPVTPPRGRSQAKHLKTKRSESQSALRGKHGRQPSPPIPTSSQPVSSQAEATIISNNAFDPFLDNVLPPSPTLTSRPSGKLAQRRQPTQPLSVPFPPTSNKMPAMARSAPVPSNMKRLRPLTKRSSTVQEFPICDDSSEYDPAPASLTPRRLYDNGPQTAPLSAGAPGTFPFTDFGGHSISAPPPSPNSPKKSRKHRRTPSEGVFHMSSDEEVSSGPGGYVLNPQVKSLFGLANVTPMKTSLAASPFVTPPSSRTVTPRARDSSPSGGSLPPVREGNEKAGFFASSTFQNSPSPDELPDPLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH50</accession>
    <name>A0A9P6EH50_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_906566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH50"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="49180" checksum="E4D9AAF349C69AB6" modified="2023-09-13" version="1">MTLPSELHDLIIDQLAVSDPDSGDTLAGSTLVDRQIALASCLMVSHSFRERSLLYLFKVLKIKGSALHVIPQVILLIAILEGESCLNTSSMPPASQFIQEFHLAPEGVCFKDLESAKLFSTLLRLIWTRMKQGFGPKKFVVSLPRTIWNETVPSLKDEMTTLAQSPHLKHLDIKELSLIPPSLIHESHIIGLSLTRTRYWTKETIPLPTDLESIRPPQLTQLECCGFIPELARPEFSSICKTLFAKLKSFRWISLEFQLKNNLKQILLLSASSLEKLDINCMFYSELDNIENLAAMVNLQRLRLEIHYVHSGSKLGLENFFNIKTPASKLQNIHFTFKTAFKSLQNRDGSPFSALFELKDSCQFLDHSLSSLQYPVLREVLVAVKVGYLANDQRSWSSAEDIRFSAMEELCIYFPRLIACTRIRFIPIVTFHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EH98</accession>
    <name>A0A9P6EH98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_301078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157850">
        <property type="protein sequence ID" value="KAF9528852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EH98"/>
    <dbReference type="OrthoDB" id="2683906at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="386" mass="41830" checksum="201B5AC71BA6A0F9" modified="2023-09-13" version="1">MSTMTSAQPGDSGSGWIASFHPVATTHTPTDPTNTNAQQIGYDATFSDDGNSLPTDTGSSGSNSGGNSSNGGLATSAALYLYTFLATLVLLLAISAAIVTRSYIIRRRNRRMIEEAIRNGTWVPPPPPDWEGRGRVKVDLSKKPQMWEAFIGEEVSEKEKVQAEYLQNPAGDGQIIINSTWRTGGRWMRWSSIWPFAASYVVPPGSTEASGANVIEAEFSDGGGVLRRRRLRMPVPPPRAMFSRIASALGTSNTPTEAGDMTPKNSIPMNNLYNHRKHLASMTSPTPMKVAVLIKMPTPPSPPNTSRSSSQTASGSNSLLTVPTLSTATHTQHEEEEEVPLPHIELGVAEVILLPRWRPEDDDEESMDEGESDITERTRGSRSLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHB1</accession>
    <name>A0A9P6EHB1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_853538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157849">
        <property type="protein sequence ID" value="KAF9528974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHB1"/>
    <dbReference type="OrthoDB" id="21643at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48029">
        <property type="entry name" value="NUCLEOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48029:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63526" checksum="92E58F28027C732D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHN2</accession>
    <name>A0A9P6EHN2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_279639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHN2"/>
    <dbReference type="OrthoDB" id="10255964at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16980">
        <property type="entry name" value="VHS_Lsb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045007">
        <property type="entry name" value="LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789:SF2">
        <property type="entry name" value="VHS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="2">
        <location>
            <begin position="263"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9529032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="397" mass="44786" checksum="38BE3C82C36C71E8" modified="2023-09-13" version="1">MKRLFGHKPKSAKPSKDFGEELPKQPQFSTPLYQKLATTGAQVHGSNISQPSLQHSTQQIPSPSEDDWQQQAVPPVHQQPYPPPPLIHTPSRSNSLNSIPHMPAASLPPPPRSASPMSTMSMGGTRLLRPHDQDRKVAPSALGILGALNPPRTDGALHHRSGDRGYSEGSRTETITPSESGHGHGHAPSDREKEKKKGFWSRDKEKEKEREKEREREREREKEWQREVQQRKEEYDRGQRERPRDGPVRREEDPQDELTRMIGYLTATASEDWSLVLEVCERASANEASAKEAVRALRREFKYGEPAAQLSAARLWAIMLRNSSDMFITQSTSRKFLDTLEDLLSSARTSPVVRERLLEVVGAAAYASGSKKGNDREGFKGLWRRVKPFDKPEEVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHX2</accession>
    <name>A0A9P6EHX2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_852890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHX2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="87" mass="9520" checksum="3F246B979293A59B" modified="2023-09-13" version="1">MHSLALVLPCLFYFSRNLLSRSSKKATLRRTHSCSSDIALACLIAVIIGTVVIFTLAASLLIGAWSMNYTTKTAKLYLQLVSDVLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIA3</accession>
    <name>A0A9P6EIA3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Epoxide hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_812411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIA3"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9529179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="409" mass="46941" checksum="90C84D85E3F44E43" modified="2023-09-13" version="1">MTNTEPRPFSINVDQEILDWVTDRVRTSRIIPDAVQLPENKLWADGTPSSVMRDLVEYWKNDYDWRKVEAKLNSRYKMFMIDIEEAGEDIQLHFVHHRSDRKDAIPLLFPHGWPGNFTEVGDLLSLTAPEDPKQQAFHIVAPTIPGYVFSSPPKSPDFNITNIGEVYHKLMVQLGYPKYVGQGGDWGSMILRSMAQKRPESLVAVHLNLVFAGVPSIWHPFVLMKLILRMFTEDEKKRLGRMQNYLTHEIGYATIQKTKPQSLSYGLLDSPVGMLAWIREKLNNWSEPDYVWDKEVVITWTMLYLLSNSAWHARLYKSSLPDLHPQLILNQSIPSTVAFGASLFPAEIAYVPRWWAQGSVADNIVFWKEKQKGGHFASVEVPDALKKDLLEFVNLLPKATKVSLREQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIR9</accession>
    <name>A0A9P6EIR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cryptic loci regulator 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_905381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIR9"/>
    <dbReference type="OrthoDB" id="2421327at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070824">
        <property type="term" value="C:SHREC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038986">
        <property type="entry name" value="Clr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031915">
        <property type="entry name" value="Clr2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046:SF1">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16761">
        <property type="entry name" value="Clr2_transil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cryptic loci regulator 2 N-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9530438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="812" mass="90748" checksum="640883B48B54CCCC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ94</accession>
    <name>A0A9P6EJ94_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_851905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ94"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="1">
        <location>
            <begin position="63"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="108" mass="12087" checksum="6C9CF0994C5E840B" modified="2023-09-13" version="1">MLDDVSTPVKEIHFDWELEDEDENNYLERVTTPNGTSRFVYIVSIQLGASATTEQILHQVGLEKSDLMSSWKYGFAGTFTSNQLSKILANPNVESVAPSHAAVQDWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJH5</accession>
    <name>A0A9P6EJH5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CTLH/CRA C-terminal to lish motif domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_190146</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FYV10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJH5"/>
    <dbReference type="OrthoDB" id="1933455at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16659">
        <property type="entry name" value="RING-Ubox_Emp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="8">
        <location>
            <begin position="161"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="313"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="7">
        <location>
            <begin position="313"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9530241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="408" mass="45934" checksum="0DD2E9D42CABFE6A" modified="2023-09-13" version="1">MSSKVNLEGIMLFEQPFARVPFENYRKIFRTSQKNLERDLTAVQSSANELSAKGTTGSLSNEDALNSIDAMIGKVEGLKKKLSDLHETAGTPTQEVMRERLHHLATVESLQNTNETEFSRWADTRLDRWLVDWCLRSGKEGSAKSIAKEKGIETLVDIDLFSDIRRIEEALSKHSCTEALAWCNENKAALRKAKSTLEFELRMQEYIELSRKRKTIEAIAYSRKHLVSWQDTHLAQIRQLSALLAFPPNTLCGPYKRLYDPSRWGSLAKNFRFAIYNLNTLSTEPLLHLSLYAGLVALKLPQCFDHATKNVDCPVCDGESASESGPQPLGLGKLAREVPYSHHANSTIVCRLTGKIMDADNMPLAFPNGYVYSREALEDMAARNNGIVTCRTTGDTCEFRKLKKVFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJS3</accession>
    <name>A0A9P6EJS3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_850044</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9531026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJS3"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26008" checksum="F429B73C70533321" modified="2023-09-13" version="1">MSKVILVTGANAGIGFELVQLLAEKGHVVYVGARNPVSGKEAVEKLTANGLKNVKFVEIDVNKTSTITAASKSIESAEGKLDVLVNNAGIANFQKDQNALTIDVSTIRETMETNLYGLIETSKTFVPLLRKSTTGAPVILNVSTDMASNWLQSQPNSVLHVVAYNTSKAAANSYTIALANELKKEGFKINAVTPGFTSTKLNGFRDGGKSTRDGALALLPWALLDKEGGTGLFIDEHQKELKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJT3</accession>
    <name>A0A9P6EJT3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_179823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157840">
        <property type="protein sequence ID" value="KAF9530406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2122982at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="873"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="873"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9530406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1307" mass="149890" checksum="C304748CF9F4AA57" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJY4</accession>
    <name>A0A9P6EJY4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 43 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_868240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJY4"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9531131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="315" mass="34319" checksum="BAF8D4AF623DDD0F" modified="2023-09-13" version="1">MPLYLNLLSMFEGYSAAATYTNPLKASQGSDPFIVWHEGYYYLLTTTWTNVQIARATTLGGLKTASPKIIWSDATPSRCCNVWAPEVHCYYVAGSSDTLDNQRIHVLRGDSNIIWDSKWTYSGRIAIPNRDIWAIDPTILIIGSNRYLVYSSNDGAQGLWIAPLTGPTTVGNTIRISEPSYSWEKVGFGVNEGPAALYHGGKTFIVFSASYCDGTGYKLGRLDFTGTDPMSASAWTKYANPIFSSANGNYQPGHNGFFLSPSGNQIWNVYHASKTSPGACDGSRYTLAQPVNWNSDGSPNLGSPLSLSTSITEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELI4</accession>
    <name>A0A9P6ELI4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AAAP amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_809363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELI4"/>
    <dbReference type="OrthoDB" id="1718410at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050367">
        <property type="entry name" value="APC_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770">
        <property type="entry name" value="AMINO ACID TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770:SF7">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9531070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="712" mass="77562" checksum="CDB505D98636A4DD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM36</accession>
    <name>A0A9P6EM36_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Glutamate synthase [NADH]</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">CPB83DRAFT_891053</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="24">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="24">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000207">
        <property type="entry name" value="Glutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000006">
        <property type="entry name" value="Glutamate synthase (NADPH/NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000124">
        <property type="entry name" value="Glutamate synthase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18 24" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16 24" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="26">
        <location>
            <begin position="60"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="2126"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="23">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1189"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1195"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1200"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00057049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00068518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAF9532316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2145" mass="235354" checksum="B42034E33096A1AA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMC1</accession>
    <name>A0A9P6EMC1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_848689</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMC1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9531765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="511" mass="58456" checksum="9BB75F210A0FC529" modified="2023-09-13" version="1">MSLSSLLIQFLLQHQLAIVGFLTVGYFLTLSYLSGPARKLRHLPVVGFTLPLLSQVSCIRFLMDTRKAMGEALLKWPTSLFIVPALCEWVVIATEPALIDDIRKAPESVLSATTALREGLQTDHTMGPHINDNQYHVPIIRAQLTRSLPHLVPEVHDELVEAFKDYIPLTEDWSKVQAFNVMANVVSRASNRIFVGEPLCRNYDWINLSIQYTFDVVQTGQILRFFPSIMRPLVVKLISQVDKRTKIALKLLEPLIAERRKEREGKSREYHGKPADMLSWLMDEAKGIEADDWYLTSRILTVNFAAIHTSSITFTHALYYLAASPEYLKPLREEIEDVTSREGWTKEALDQMVRVDSFMKESQRLKPMANYLMNRLVMRDYQFSNGVTVPAGSVVGVMLNHHTSEEIFEEPYKFDGFRFVKMREQAIAAGQTEKKFNMVTTGIESLGFGHGRHACPGRFFAASELKLMLAYLVMKYDVRTVEEGVRPKDFYFMQTCIPNMTAEILFKRRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMR1</accession>
    <name>A0A9P6EMR1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_847148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMR1"/>
    <dbReference type="OrthoDB" id="2507647at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="561" mass="61434" checksum="5E5B2F3B776C3771" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMS9</accession>
    <name>A0A9P6EMS9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_849078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMS9"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9531474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31927" checksum="A137D5B25AF3EDCE" modified="2023-09-13" version="1">MSMLSPSSIWFITGATSGFGKRFTLTALSRGDRVIATGRSLDKLQSIVSSLKPEDAERVRIQQLDVTAGEEQVKSVVNQAAKHWGGIDVLINNAGVGYHGLMEEGGSKLLRRQFEANVFGVVDVSIAALPYLRQSSNGRLVVIGSRSAWKAERLGLGPYSASKAAVGAFTENLMTEVAPFNIKVLLVLPGAFRTEGIYGQRFFQDNSMPIHDEARTTVMRRIAAVSGNEPGDPDKGAEVLVDIVQGRGVAKDRPWPSYLCLGEDAETDVRYKCETVLKSLGQWSDISRSVKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMU9</accession>
    <name>A0A9P6EMU9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_809231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAF9531504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <begin position="12"/>
            <end position="31"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="113" mass="12730" checksum="AC45C6556897E809" modified="2023-09-13" version="1">MAFQVVIPLIHSYSATAQALILLVLLVGSYVHRTTRLVIAALALLLLAFKTLVPFVRLLFWAFKGIAWMGFYVHYFQVALGFMVTGATIFLNGVEWLGKELEKNARGERNDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EP67</accession>
    <name>A0A9P6EP67_9AGAR</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CPB83DRAFT_807700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
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            <taxon>Agaricineae</taxon>
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            <taxon>Crepidotus</taxon>
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    </organism>
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        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
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                <consortium name="DOE Joint Genome Institute"/>
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                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="12"/>
            <end position="32"/>
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    </feature>
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            <begin position="76"/>
            <end position="96"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="108"/>
            <end position="132"/>
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    </feature>
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    </feature>
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            <begin position="180"/>
            <end position="199"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9532362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="323" mass="35277" checksum="50ACC6F3CABE550E" modified="2023-09-13" version="1">MSSNSFRDRVLPLAIFPALSAVAVRLLMLPLIEAKLDLDTGCRALGITGKSAIDNPLCSLVDFFTVLMHDTVGQSFLTYAMGISLPLALIPAVEAYRPGQTKLLKYPMAWLLVSQVVSIGITMPLYWMISVLTNGPRKIRHGTTATYRQADVLALAFGLVVGAVVPSVSMMVLDDPVVTALWQIYPAYVAIAQFIHLQVRPHTQHSHSGYTALQVIYFATLLLSSSVHMSTIWPMLKDIESLKTLLIPTLGSLPSSANAAQFCLNFLKWDVTLAYLSTIIASFWSADSLQQGTIMAFWYVLSIPLLGFGASVMGVALWRNGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EPM5</accession>
    <name>A0A9P6EPM5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_903454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
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                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
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    </feature>
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        </location>
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            <end position="1058"/>
        </location>
    </feature>
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            <begin position="1143"/>
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        </location>
    </feature>
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    </feature>
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            <begin position="1478"/>
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        </location>
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            <end position="1491"/>
        </location>
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    </feature>
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        <location>
            <begin position="1537"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAF9532971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1578" mass="172771" checksum="85BD08107CC479FF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQM0</accession>
    <name>A0A9P6EQM0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_880389</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
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            <taxon>Agaricineae</taxon>
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            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
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                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="988"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1043"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1128"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1228"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1258"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="294"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="697"/>
            <end position="931"/>
        </location>
    </feature>
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        <location>
            <begin position="1045"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1328"/>
            <end position="1607"/>
        </location>
    </feature>
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        <location>
            <begin position="389"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="664"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1447"/>
            <end position="1488"/>
        </location>
    </feature>
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        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
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        <location>
            <begin position="1452"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1466"/>
            <end position="1479"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9533294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1625" mass="181452" checksum="4C2313E31788B82A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQT9</accession>
    <name>A0A9P6EQT9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_846077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAF9533218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040137651" evidence="1">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="159" mass="17476" checksum="32ACA130BD4349AF" modified="2023-09-13" version="1">MYLVFLLSRLFLILATVFAGTPSIVHPANGTSINPGETFDFFYNSIADYGVSSYNYTVWLFTSPPTFPFVQVENFAFGYYFGRFAEPNYPGNPNPPNPPPAQLTMPNFATMEKGFGNGASAHNVTCFLTVLEEYATGNGSVGYRMSLSSNHISYNNTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERA5</accession>
    <name>A0A9P6ERA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_473746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERA5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="17332" checksum="C129F0FFC7323E73" modified="2023-09-13" version="1">MALRGCKVFHAFKITLVCLLHIALIALCTIALAGGSADRAERGAILLSLFSLGAVVFSITYKPFGRRWTWDRERGTTTFSVLAFLGIFLFLTIASRNYRHSDQRGTLKDDFASMGERAANVARMATYFSFLTAFIPLGIAHAMRAVYEDEWPACKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERF8</accession>
    <name>A0A9P6ERF8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_923874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERF8"/>
    <dbReference type="OrthoDB" id="3438340at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="320" mass="34582" checksum="C5B3B72C7CCBB7FF" modified="2023-09-13" version="1">MATEEFNEDSIDTETLQAQIDLSMSFAQNLISSWMEPAQLPTSTRRKDLEKELMENMKRPPRLGVGASAVVATQSLGRETARLKSKLTGSKRTREEVDEGHGTTALSDAEDESRTGAISKKARPDPFGGVHGKKKKKANEGPSSTAKPELSVQTTPPATALRNIKPSTPVVEIKLESGHEESKISTTEKKKKKRKCLPEPLFSQELSLTRSPLAIVPAQGKDELPSLQIASKPMTSSPKQRSTTSTLSTELCSPDVVAAHLLDLPLLNLNGPPPSDGESDAPNHSPIASPKKKRKRRKKKKTLPIADSTEGVANSSNTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERP4</accession>
    <name>A0A9P6ERP4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_843066</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ELP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERP4"/>
    <dbReference type="OrthoDB" id="27911at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037289">
        <property type="entry name" value="Elp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="95"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="189"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="296"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="405"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="608"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="653"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9534863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="790" mass="86810" checksum="D3C0E6EC1320A788" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERP5</accession>
    <name>A0A9P6ERP5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome c oxidase subunit VB-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_866751</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERP5"/>
    <dbReference type="OrthoDB" id="10249250at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602124-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9533819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="156" mass="16813" checksum="87DA4196CF69C8D9" modified="2023-09-13" version="1">MFRNAIRAARPIAFAARTSSKPSTSAARAFSTSVRVLSGGPPPPQLFGEGAKAGTVPTDLEQATGLERLQLMGEMEGFAVFDDSPLEASHLGTKANPVLVPSYDIERIVGCTGVPADSHDVLWFNLKKDHPTRCTECGSMYAIDFQGEEHHDAHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERS3</accession>
    <name>A0A9P6ERS3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_889659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERS3"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="632"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="675"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="738"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="761"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="828" mass="86961" checksum="97AA82DCDDA86A92" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERX4</accession>
    <name>A0A9P6ERX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Carbohydrate esterase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CPB83DRAFT_879920</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9534052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERX4"/>
    <dbReference type="OrthoDB" id="2125469at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040343140" evidence="12">
        <location>
            <begin position="18"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="13">
        <location>
            <begin position="37"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9534052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="250" mass="27381" checksum="F314EBCC5EDD1708" modified="2023-09-13" version="1">MIASSAVVLALALSVSAGVTQRKRGGGQLVTSCTVPNTAALTFDDGPYMYMTEIVDMLKANDAKGTFFVNGHNWGCIWEETNMQNIRYARDNGMQIASHTWHHKDLNTLTLDQLRSEMSSTNDAICKILGTKPAFMRPPFGNYNDDVLSVVGEMHQTAVTWNLDSGDSMGAEVSAQNQACDDVIAQHPQGIISLQHEVYEPSVHQVLPSYISKMKEAGYKLVTVAECLGMEPYFDGECPVSKRGDDSYAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESA2</accession>
    <name>A0A9P6ESA2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyrimidine 5-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_843901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESA2"/>
    <dbReference type="OrthoDB" id="1065058at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="246" mass="28055" checksum="4D36228E2E5315B5" modified="2023-09-13" version="1">MACTTQDDRPIVFFDIDNTLYSASSMISHEMGKKIHAYFVSIGLSHEEASELHLKYYTQYGLALRGLVRHHNVDPLDFDAKCDQALPLEEMISYSPQVQKLFEDIDRSKVRVWALTNAYRLHAERVLRILKIDNLVDGLIFCDYLMKDFSCKPEPEFYRMALRAANVGSPANCYFIDDNRKNVDAARAEGWGHCVHFCEKGIEHMEGGKLKAIDDAREPGASDNDVVDVTTLDELRTVWPEVFKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ESD7</accession>
    <name>A0A9P6ESD7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_887971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ESD7"/>
    <dbReference type="OrthoDB" id="3054878at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1015" mass="111733" checksum="A4BA1E6AF6BC68BC" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETL5</accession>
    <name>A0A9P6ETL5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_226174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETL5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="65" mass="7521" checksum="19EBAD1D194CA0E3" modified="2023-09-13" version="1">MFRTFSERAFPGWLNLAFNVRCCAIRVRESKNLRTGSIGFAAVLLHPICLACEFVMNKMDMEFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETU8</accession>
    <name>A0A9P6ETU8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_841568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETU8"/>
    <dbReference type="OrthoDB" id="3071370at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9535320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="50028" checksum="8CC884314252D0AD" modified="2023-09-13" version="1">MSPLVNELPAELLELIIDQIPLSSPQGRKTLCTCLLVSKIFFLRSRSRLFYHVDLYPDDDRTSRTTALRILLESEVDENNGYPSLGRCIKSLEVIWPPSAFHSTSVDISHEEFRKHLSFDIDDVAAILSVLARTRLVQTFSLYFADTTGFSNFQSITPIWNAVDGICHSPTLESLNLEHLWGVPHDVFDIRTIKNLSLSNVTSSDELDFVRNAENDGGTLPPSQLRCFTYTFRCPFSSRWLQTLSPFSYLHTLVVKFDSVLPDNPNSQFDTLLMLCSGTLESLSISLDSATPVFKLYPHLLQRLTVLRALKFTVHSNSPPVFGAQHDYEPSTSFTRTHDVVESLETLQSVPNSLQSIGVDFRARLEVEYGAGFRSDHDWQKLGDKLIESRYSLVQKITVALLVNASMSGEKPYSQAPLFNIFSKRWEARYPTIPIKVVEIAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETZ1</accession>
    <name>A0A9P6ETZ1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Xanthine/uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_866381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETZ1"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042907">
        <property type="term" value="F:xanthine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF2">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="534"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="563"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="583" mass="62040" checksum="CCD193C1217C8287" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EUJ7</accession>
    <name>A0A9P6EUJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_843224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EUJ7"/>
    <dbReference type="OrthoDB" id="3059337at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9534954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="44351" checksum="A4C13361E0CDAC9B" modified="2023-09-13" version="1">MPALGETPITSYFSRTPSLSKRKNVPEDDPEPANSGGKGALKRLKQSPASASKHSNSSPLKKVKGSDIEDFFQTNNRNGDSNLNTPMTKMRSKGKATALPTPPTTGGVAASRRTVSEAVYTRQPLTPLPRAAASPSKQLPTPSTLMKPAIPKRRLDEFQTQAGPPWSMVSADSEEMSVPSSQSQLSDDVELSMPPPRTLLTSKSTLLDFDDDDDFVPSSQSQPSLNIITSPRRRPRKVQPEATFEIPTSQSQERELEIPPEFINRDQGRNSPRKSPTKLPQRTLSDELFPIPIQESPFAGIFPDVDNLADTEDPPGDTANFPPSQGSVTESETEDEDQEDSRRLHKASSIRKPKFSQLSTTQSSQSSIASYADASFSSLPDAVREFRSMFGEGDGSYPADFPESLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JHM7</accession>
    <name>A0A9P6JHM7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_841128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158015">
        <property type="protein sequence ID" value="KAF9521611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JHM7"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="526" mass="59360" checksum="6437453FF982F95D" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ70</accession>
    <name>A0A9P6JJ70_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157934">
        <property type="protein sequence ID" value="KAF9522783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ70"/>
    <dbReference type="OrthoDB" id="3058759at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="143" mass="16735" checksum="E5C873EF0718D0D3" modified="2023-09-13" version="1">MIQRGYMKKGMYDYCVDLENHVVVLDERTDWSIIQPGTRIVMRVILERESSTFFMVNQCPRPHCGVWNYNVFGLRSSNCQGCSGRFQVTLANRRTCRNHQRRSSDQGLMLLRNFHIQRLPGKWEPRDYSCQVVMKGGFVAPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ87</accession>
    <name>A0A9P6JJ87_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_899136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157927">
        <property type="protein sequence ID" value="KAF9523007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ87"/>
    <dbReference type="OrthoDB" id="5595379at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="455" mass="50022" checksum="18DB64D1A570E4CE" modified="2023-09-13" version="1">MSSTPSDDALSWLLSISATCESSPIGLSSPTDYSSDFTASDWLQLSPTLTPLQDVTTSARVNYPQESLNYRYNISDACRISQTLFSNDTGSLMALPSSVLPGAFNRHNRMLSLGSEPSTLLNTPSPQALPLYSSLGTPNHPEIFDTSRHHQDSPRLFSSPSSKLFQDLQKSPLESYYNEAFFATRFAGTADDDFSPVVRADDLKKPVPSAKANPQTRKKKQPRKMARKPQPQPSAPSAFVQRLESAPLPLFGVSSISSRPLPILTGAQRADMPLLLSPVKLAPPMVTTTLLNNYSTPLPALSLSASPLAYSELPGLSPLTPLESSPQAAISTPLKLTIKFKRRQTNPSTPPRRSKRRRTAPSSDVHTIQDSPEVARAVVVSKQVDPQTEAPSTATFRPAYSKRTLPERIPISKDFSLFYRRFPASSWYQKSESEYDFLLFPAHVFNRQMIGLPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJX4</accession>
    <name>A0A9P6JJX4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Structural maintenance of chromosomes protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_690784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157918">
        <property type="protein sequence ID" value="KAF9523413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJX4"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="251"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9523413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="68545" checksum="65F390334B784BAF" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK09</accession>
    <name>A0A9P6JK09_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_691922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157919">
        <property type="protein sequence ID" value="KAF9523354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK09"/>
    <dbReference type="OrthoDB" id="3265734at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02795">
        <property type="entry name" value="CBM6-CBM35-CBM36_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="256" mass="27509" checksum="23938A3DB36DB1AC" modified="2023-09-13" version="1">MSSKSTIVDDRDANGKFTGQWRQDGVAEENNHSTTYTKVKGAQAQFTFTGTKIGIYGTIASKKQPEQKHNPESTYKVDDGPEIKFTGKLGENVAFKQLFFQSDDLSAGKHTLTITNQVDDGFLYIDYLEIQPVATTSSSFLPSSSLRSSSSAVSASTTAQQASTVISHATITTVVDYTPSPSADSSVDGADAVGTTATGTNNATKIAAGIFGGIVGVAFLVAIIVVALKKRKDKRRDEAIDFYANRSPWHQKTEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKV7</accession>
    <name>A0A9P6JKV7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_897950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKV7"/>
    <dbReference type="OrthoDB" id="2745898at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="272" mass="31169" checksum="CA48E1102CE6377E" modified="2023-09-13" version="1">MAMKHLLRLPSLTRLRLENLIKVPLDAIATNVKHLSLEKVSWKSVEESAFSSSLPPAIEVLISDYAPSTKALLSSIRPDNQPVVLLKSLTQVEVGGINQDALETCRLVASTSTVLTVIRLKYPIRNTFAGLYDAISPSFDTLRHLVLVTSGNYQNPDPYQDACEELQKMTNTKIQSITFRVITECDLEGTIEDNWDQIDKLLTSEVNWPCLTEVQVEVKIWRFCRPKSAFDETMKNLSKLYFKRLLASKRIHFVYECHNDRYLYMNKPDMWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKY1</accession>
    <name>A0A9P6JKY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD-dependent protein deacetylase</fullName>
            <ecNumber evidence="8">2.3.1.286</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_861515</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="8"/>
    <dbReference type="EMBL" id="MU157901">
        <property type="protein sequence ID" value="KAF9524270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKY1"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017328">
        <property type="entry name" value="Sirtuin_class_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037938">
        <property type="entry name" value="SIR2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="14">
        <location>
            <begin position="16"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="331"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9 12">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="44"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="54"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="218"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="242"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9524270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="395" mass="43880" checksum="1E9B3DE2B812A4AB" modified="2023-09-13" version="1">MFSSRRSRPINQGNPKVLKARDLPSVVQYIESSACENVMLMLGAGVSTSAGIPDFRSPETGLYSNLQRLNLPHPEAVFEINFFRRNPVPFYTLAHELYPGKFRPTITHSFIRLLAEKKLLHTCFTQNIDTLERRAGVPDEKIIEAHGSFATQRCIDCQRPYDDAKMKDHIKRKAIAKCDSCQGFIKPDIVFFGEGLPSAFARAVPNLRKADLLIVIGTSLTVHPFASLTGMVDESCPRVLINMERVGDFGSRTDDVILLGKCDEIVLELCQSLDWEKDLNRLWELTKASVVTEPEEEVEESKSEELPEPKSAHPRDNLEILAAVEARLAKMSVKEGKEEGKDLEPSTDTVPSNTTASANSTTKEEAEKVAENIVDAIKGAPQGDVLKNDPATMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKY9</accession>
    <name>A0A9P6JKY9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_610299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157899">
        <property type="protein sequence ID" value="KAF9524388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKY9"/>
    <dbReference type="OrthoDB" id="3263055at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="164"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="326" mass="36092" checksum="8C9877B4C205BF6F" modified="2023-09-13" version="1">MHPFVLHDTLGAAYIGVMLAAILHGVSIVQAWYYFGHQNDRWTIKGLVTAVMVFDTIHQALIIHTIYSYTITYWGEPEELDKLVWSLIVEVLFNGLTAFLVQSFLTLRIWRLSNRSILLTGFALCLVFAEFGVLLAYTGLALDFDTYEQLAKLKALSITVNALAAAGDVMIAVTLCSILHFSRTGFHRSDTMINKLILYSVNTGVLTSLCAIGSLISIVFAGQTFYYIGFFFCIGRLYTNSLLATLNARKKIRGCGESSDHVSLSLRDCNINTSTKLTNASVRRGANISIKIDTTKEFASDLAEDNDTEKLSESVSSGTNLEKHQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLB5</accession>
    <name>A0A9P6JLB5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_860086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLB5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040206437" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="9105" checksum="A13AED4649ACF20A" modified="2023-09-13" version="1">MGAIHTFSRILLYVLATLRATNYAGFCPVMVDLPRELWDCITSYLDDKEAWKLRNVNHILRQIIFVLATWASCTIFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLR5</accession>
    <name>A0A9P6JLR5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_941997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLR5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="12881" checksum="066469B4C563A2D7" modified="2023-09-13" version="1">MDFWRPLALQLKCRNALFVLMVSSVLMQRISESSISIIKAFLLSLCLTIKPLTLQNQELHLYPGLPPQLAVTRTTIPQFLLSKRRCFDQPDSRTPTFYSSIKTCAVLNAGLSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JLS1</accession>
    <name>A0A9P6JLS1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vesicle transport v-snare protein vti1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_859229</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157882">
        <property type="protein sequence ID" value="KAF9525572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JLS1"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="128"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="43"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9525572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="227" mass="25498" checksum="57CE2AA10B78AD23" modified="2023-09-13" version="1">MDPTPTSLFESYEQDFRHIIHGISDKLQDGGKNQIGEQRKAALRKVELELDEADDVVSQLEVEIQGIPNSVKAPYATRLKQAKADLSKYKKLSKDLQFQATRSDLLGGYRADSSRSDDPYGENSDRTRLLAGTETLNDGSRRIQDSTGIALETEAQGADILRSLRGQREQIENSRSMLNTADIHIDRASGTLKGMLYQMKKQRFILSGIGIFFVVLILTILYFKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM90</accession>
    <name>A0A9P6JM90_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_943586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157884">
        <property type="protein sequence ID" value="KAF9525424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JM90"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="5"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9525424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="288" mass="31138" checksum="E726022BECB22550" modified="2023-09-13" version="1">MSPQLVWLITGTTSGLGRHLAQEVLRRGDKVIATGRARSIAKLDELKNEGADTLELDVTWPLEKLQETAKEAVSIHGRIDVVVNNAGYVQIGVVEETTPKETLKQFNTNVFGALNVSRAFLPYMREKKTGTIIFLGSLAVICGLPYAGLYAASKWALRGISSSLHAEISPLGLRSVCVELGYFRTALLDGDQRTPAISRISDYKELSEKAETGFGAANGKQPGDPLKGVKVFVDLVKGENGTAGKPFPPSLALGSDCYKTCKETSEGYLELLDGWKEVSVSTDFAEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMK0</accession>
    <name>A0A9P6JMK0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_513020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JMK0"/>
    <dbReference type="OrthoDB" id="2969099at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9525918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="253" mass="28607" checksum="612A3901AF687639" modified="2023-09-13" version="1">MAPSSRPSKKNKRKKSLSDHGGSPQKQSAQRPKKKAKKHHEPSGSEYSSDTSIDKMDTSEDEISIKKTKPMHAPAGRPSNQTKRMSKTGNSAHVLPSPAQSTLLEPVTPPQKSKKSKSLLNTYTPRTAQAVAFSVQPPIYEIDVSPDQKQQSRHRSGNSTLQTLNKIKHSSEDGWTLLGKCRTEQLCWQFDKWKNDYSPQTYDVCDQLVVIQFLGHPCDRPKDICARPFLIQWDRTLDRKIIKTLSKKSKPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNK7</accession>
    <name>A0A9P6JNK7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_398651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNK7"/>
    <dbReference type="OrthoDB" id="3037355at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9527492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="417" mass="46878" checksum="520E3C6B54DCC5EC" modified="2023-09-13" version="1">MSFTAGISINSLTTGSTIKAKVLSHEDDNYSQTFEIRIDENLQSAFRYLEKIFSEKCGEVKYVAIAIPTYFKEQDREFVNTTGKNVFSHIRTLKNLHLVHSNSLQVDEHPPENHIAVEIGQDGAAGRVGVVEAEDKIMFYGDTEDVYVHDMDAIEPDVLFNRTMQPFLDRLSKNPTECGSEVHKVVVLDSSPIENHPTMGFRLHTLAQTRIRRSELPTEFVYEDGSKILDHIAKTSCKLYEDSLQPLGCIFNVMCFNVSIAKVDGFVKTILRRHQTIPTQGQAVFTTAKDNQTEVHLHIMVGLAHRVADNKLSGKLVLRGLPPKSRGEVLIRVSIMVDYYEQMTVVAEEVGLDLIPVTNGASATIEFMTTSGEANLDARLIDQLFVDFRKLDVEEDLRQSQEVEQRWADSSASVRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNV4</accession>
    <name>A0A9P6JNV4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_908022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNV4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="189" mass="20981" checksum="B4BF2E9D0964FCCF" modified="2023-09-13" version="1">MLEGTSYSQPQPTSAAILHRITSLLVEERQSEQMAAQSQMQGVMVYAQRQIDDAKAQQDAVEEKLALANQRIGYLEALLDEMYTKSPSLASKESDSETAIRVAFTTLAASSFSNEEVEDTTHLFMARWIPLINELGSTVILPNALWSSPVIDSVIQMCLNNVLHYKAQIEGQERTIQYLLANPPGYGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPU0</accession>
    <name>A0A9P6JPU0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_767657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPU0"/>
    <dbReference type="OrthoDB" id="2898509at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38293" checksum="B122A0036E8E121F" modified="2023-09-13" version="1">MTLTRIQQTRLANLSFTHLTGKSGRNPTAVFVGGTSGVGEGMARVFAQHTNGNADIIIVGRNADAAEKILRSLPVGSAIEGGSLPARTFHRCDVSLLKNVASLTKTILSQHPKINYLILTTGFVSLARRTETSEGLEDRLAVHYYSRWKFIYDLLPAIQKARDSGEEGGVMTVYGPNKGLYINAGDSVLDWDLKGESWSSRTYNNFMIESFAALHPSISFVHSHPGWVRTPLGANSPSFLIRVADHLKFLLSPWLVSIEEGGEYMWRGLYRHGGIRYDDEQKLEEGGKGGAWWTGWYGDDLEKPPPASKQVTKDRKVEALLWEHTSGVVGSSLKDYILERERLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPZ6</accession>
    <name>A0A9P6JPZ6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_361813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPZ6"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053152">
        <property type="entry name" value="Hydrolase_YcaC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43559">
        <property type="entry name" value="HYDROLASE YCAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43559:SF3">
        <property type="entry name" value="HYDROLASE YCAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="39"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="244" mass="26460" checksum="8450668697E482F5" modified="2023-09-13" version="1">MGHQSRSFLSVPLIFTVIIHFLSYTVSAFTFERIDKNNTVVLIVDHQVGLLQLVRDYQADEFRNNILAHAALAKVFALPTVLTTSAETGPNGPLPKEIVEMHADAPLIKRSGEVNAWDNADFRQAVSATGKKQVIVAGITTDVCTTFLALSLLAEGYTVFANADASGAMSRRTADDANDRMRAAGVHVLSSFAIASDLMRDWRNSPGSAQLLPFLDQYSAQLAYIVRGHVAAINNGTILPGEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQB6</accession>
    <name>A0A9P6JQB6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_852708</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="MU157846">
        <property type="protein sequence ID" value="KAF9529457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQB6"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 12 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="258"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="469"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="16"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9529457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="657" mass="71817" checksum="1D8EC7FF7C4D6B26" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JRV5</accession>
    <name>A0A9P6JRV5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_131192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JRV5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="208" mass="23184" checksum="ECBCA618FB444A5E" modified="2023-09-13" version="1">MASKHKGLKAKNGPLKSVADELAMMRCVRDGAFHHFRFSLLGNLSELVSCAKKLHVGDSTRDPVQPRGHADKLSNAAISMYNNSHIMAGPNLQDYTQASHIKRAQSAGTKPTRKQIRSMVCGSKRWQRVESIAKVRLSVRKNEAKKGVVLDCRVFPKITSIVLSSTTDPRGGATGGYFEWINPTHRELTTFLRHCSGEVLQSKLRFWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JS29</accession>
    <name>A0A9P6JS29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_762215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JS29"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9530881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="188" mass="21631" checksum="86FB4360DF759A17" modified="2023-09-13" version="1" fragment="single">MEHPVQTNSSSLHPPTSSHFRPHPTPFSHPRQHLDDYRHQHSRQHQYPSETILNIRPSDLPYNAQSRSPPYASRAQVSYPYPPRPGSSEHNRPGDFSHQIHQIEEDELDGDDYDDGISSTPGTNANGNPNTSTRKHVCPTCFKRFNRPSSLKIHVNTHTGATPFRCPWPNCGREFNVNSNMRRHYRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JSS9</accession>
    <name>A0A9P6JSS9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JSS9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9530840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="194" mass="21172" checksum="53FFADB17D323B02" modified="2023-09-13" version="1">MNRCLTVLEQGDAMMRAAKRINVAEQDLGTRRGGGWDSGLVGGKTYEVKKILSSLSLFLSLFFSPATITKSIETVVKTSSNRARSAIITNSFRHGRLMPNAAYHIGDIEERGKELTLLVVECTSWPINATKLSPGFISQFHLGILVVIGYDQHQTCSISEVFLNDETPGTSPPSPSSVSHLGHNCVVKLFAELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JTR9</accession>
    <name>A0A9P6JTR9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CPB83DRAFT_784999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157832">
        <property type="protein sequence ID" value="KAF9532203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JTR9"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="349"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9532203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="509" mass="55006" checksum="4BA79C55F2234AAF" modified="2023-09-13" version="1">MKVIIVGAGIGGLSTYLAFKKHISPLDPSLQIKILESHSSPRSQTLASGGGLGLAPNGLRSIASITTNAISHIQARGFAGTSMTFRNDKGGMLGVMAVGRRERYGYDMMMMTRAGVHDALLSEIEDESVIRWGVKVIGVEEINEGEGGVLVELADGTIEKADLLVGADGVRSIVKDYLFKGEYQAQYDGLTGLGGFLPLSSIPTSLRESLPDHPVTMIFGRLGFLAYSVASPLSDPDPLFMWWSIYETDSLPDRTNIDYEDVKRQLLHRSGSWKSPYDATPRSQNDATKGIYRQLIELGCVPPSDAPLIPTNSNSSGPASSKSMSTAPRILPRYVTPRLPYWSNATAAAGTTSASKNRGRIFLLGDAAHTMPPDVGQGVSCAAEDAVVYALLLKHYISNAAAASPTTLAVSTTTSIKATATDVNSPTSVLEQTAIAYESIRKPNINKLLDLAKRSGDMKKELSWFGQVFRDLMMKLVLAFKLPETFNDVVFAYDPEEEVRKYITKASGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JU69</accession>
    <name>A0A9P6JU69_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_759380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157831">
        <property type="protein sequence ID" value="KAF9532653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JU69"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051157">
        <property type="entry name" value="PDH/Transketolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF1">
        <property type="entry name" value="TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="317"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9532653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="632" mass="69199" checksum="054B88376D146315" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUF6</accession>
    <name>A0A9P6JUF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial proton/calcium exchanger protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Leucine zipper-EF-hand-containing transmembrane protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_880535</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LETM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUF6"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="15">
        <location>
            <begin position="195"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="580"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="426"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9532923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="650" mass="72396" checksum="E783BF7EC67C00CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JUL0</accession>
    <name>A0A9P6JUL0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_845771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JUL0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="537" mass="61317" checksum="1A51E64F8014FEBE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JVY1</accession>
    <name>A0A9P6JVY1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Decapping nuclease</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_844757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66928"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:172876"/>
            <dbReference type="ChEBI" id="CHEBI:172877"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60880"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78683"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78684"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JVY1"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="8">
        <location>
            <begin position="96"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9533915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="481" mass="54135" checksum="CC9661FF16B29426" modified="2023-09-13" version="1">MASPSNKRKRSISELLTDDATVPGSENEKHGTSPPRTRRKIDENDASGQNVIVPEVESPSNDQGKVQNHETKAPTQLAFLAYPDLTRSKPSSVLFQQPSQLTTFSYTPEHVQEFTNSAMRYFVDPPSGANLSYGFERWIRKPDTRGRLDALLKAISKVKRNVEEQNGKLPEIGVVSWRGVMTKILTSPYENRDGWELNVMSINGTLYFEEHLTDARLQEKNNMEPRQKTQTYYGYAFESYCTSDSPHSSRHATERESHHGWGGDVDTNVQWCSVVRTKLGDTRLIIGGEVDCVRGKYTGQTDAFVELKTSLAIKGRHDEIKFEKKLCKFYFQSFLLGVPEIVVGFRTPAGVLTTVQSFKTIQIPRMVRGKPGAWDPLVCLEFGHRVLSLLKDITRKHSVQAENRQSVPVWRVKFVPGSGLRVNELEAAEVADVVNQEDRVGFLPRWYWNEIQDEGSLNSPEGAHKSAPAQPALTALGGWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JW28</accession>
    <name>A0A9P6JW28_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_872962</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9535126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JW28"/>
    <dbReference type="OrthoDB" id="109543at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="17"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9535126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="625" mass="71570" checksum="BB90312CD3763D70" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWF4</accession>
    <name>A0A9P6JWF4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bola protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_780945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWF4"/>
    <dbReference type="OrthoDB" id="203381at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052275">
        <property type="entry name" value="Mt_Fe-S_assembly_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46188:SF1">
        <property type="entry name" value="BOLA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9534964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="114" mass="12607" checksum="E784807DEE306C16" modified="2023-09-13" version="1">MLSLSRRVFPALHTTRSFSYTALIRNATAGSTTPNDPELTTREQTIWTKLTNKFEPSQLQIQDVSGGCGTFYAIVIASDKFTGLPMVKQHKLVTETLKEEIAGIHGLQIQTIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWN1</accession>
    <name>A0A9P6JWN1_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_842963</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31307"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19521"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132521"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="EC" id="2.4.1.265"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:31308"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWN1"/>
    <dbReference type="OrthoDB" id="1689333at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="556"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9534800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="596" mass="67224" checksum="35D77100EF6F74B7" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JWX6</accession>
    <name>A0A9P6JWX6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_842209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JWX6"/>
    <dbReference type="OrthoDB" id="2431475at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132:SF1">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9535714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="493" mass="56781" checksum="8CEA8F994D39B334" modified="2023-09-13" version="1">MSSSLSSVVSGLVRAQMGASVPSSVTNDDLDRHVAELIVKEAKKKAELYMQKGVRAYTTNSLSDSNAPRANKRFLSSIIKSTDEHNRTILKAQSDAAEEVKRERREQERQQRRLRAQEAVEARRSGGESSRRRSRRNEEDTSEGWDRWDGRTEERKKLSRNWETWDGYDEDAGDREKEERRRRSRSRERDTEKPSRPSKRVEGDDPERSSKHRRRSTRSRSPRRRHKSLDRDEDSDSRRRKRRRVGEESYRRSRPHTHSRSRSPAGRTTGTDDRKSKKRRRSRSPKYALDDLRDETSSPEPRKRSSPSTTDSVATAREAELRQHLKNSKKAVLSDQVEISARPKASTSTSRRSLTPMTISRSPTPGPQPAANLPSKMDRYFEESYDPRLDVEPLAPPQVPATGLINDAEFEGWDAMLELIRVRREDKLEKKRLERLGLLPEKDKSLKVKKKGPVEPSSAAVAERWGADAINVMDIEYSKKGSVREWDLGKEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JX39</accession>
    <name>A0A9P6JX39_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_901526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JX39"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="418"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9535863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1208" mass="138011" checksum="2D8E3306E40FD1C5" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BBF3</accession>
    <name>A0A9P6BBF3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_911777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158107">
        <property type="protein sequence ID" value="KAF9521359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BBF3"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="269" mass="30122" checksum="EED4542CD5EA0DCD" modified="2023-09-13" version="1">MLLSDSNCVIYFTSRLRAALEATQCDATLNMLRYEFFNSRFQVEMNNIYPILGRAICSNPSFMVPPLLNFLHENITTVFKFFGQPLPMSVLDIKDHLDPANDDPTRVNQDGYNYSWWTYPKHNMITEEDLEHAFQRFVESMPAQTQMELPASSIPSGCSNQQCRLMIHTMARTIDDIHNLVLASRMAHRETSDALTAEIKGIKVLNDVYNATGVAPQASEVSEIFRSKLTEQLRGGGCKSSVKAGSDSNASQTDSPTSETGLANSDDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6BE25</accession>
    <name>A0A9P6BE25_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_900646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158043">
        <property type="protein sequence ID" value="KAF9521491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6BE25"/>
    <dbReference type="OrthoDB" id="3223099at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9521491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="28255" checksum="B3744047D3361B08" modified="2023-09-13" version="1">MIQKEDYDDYEELEREEDYLKYSELAMPNKSKWSRSELNHLGLPISVRSTASIAIAIAIAIASPPPQLSTGNSENEEHEEMPFSPRPVSSAFSIAIMIKLVDGCNSTISKINHRRRERLLPFPRILPSRVDETLYRVPKSGFFQANPKFFDRFNVIELNGVTSEVFEGLLNVFHPINGNTLTYDGWLGALELATRWNMPEIRAGTICQGNLRTPRDSGVVISPLTLRTLTSCPWSRSTSGPFLPHACLALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E2Y5</accession>
    <name>A0A9P6E2Y5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_865426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158029">
        <property type="protein sequence ID" value="KAF9521548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E2Y5"/>
    <dbReference type="OrthoDB" id="6419443at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="90"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9521548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="281" mass="31285" checksum="E219EEDDD65CC8FD" modified="2023-09-13" version="1">MSLRQDVLKSKIEDIEGRLRNARLNANGTSRNRTFQDEDKEKEKDDSDSDDLINVVSLPGTPSRTRASSPVRGASSRPLKGPLMLSGNKTDPLKAFPTELSQKIFARLSMKDLARCSLVSRKWGKSQTLNYVWFQHYRKENFHDDSLPPGKWTKRESKQNWRQVYLKEMKDRSPPSTPYYSRGGSGYHTPSGGGSISRSISANGGASGLGSGYQTPRELKEEQWRAEAETTRPGKVEMREMYKELGGRKSRAKVKLGSGGAAAKGGKGVRDRGGWEGGDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E363</accession>
    <name>A0A9P6E363_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_900442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU158006">
        <property type="protein sequence ID" value="KAF9521653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E363"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="97" mass="10476" checksum="1C9D5BA026F1207D" modified="2023-09-13" version="1">MFRLSQLGLTSTVAPPMGCYYTAEVLRQNVNNGLIEFHTELCTGEASGSLTVDDVAKLLFNGHLPPTIILNEMPPTPGQPQTSICIQGSKVLYAILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3S1</accession>
    <name>A0A9P6E3S1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_777751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157967">
        <property type="protein sequence ID" value="KAF9521999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3S1"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9521999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="58" mass="6637" checksum="523021D36F32DE2C" modified="2023-09-13" version="1" fragment="single">MIDDDNITEASAFPLAFGIAYKKSTVANYKRFWKKSPQDFRSAFLSLGDDPKASWKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E3V9</accession>
    <name>A0A9P6E3V9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_840798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157965">
        <property type="protein sequence ID" value="KAF9522022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E3V9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="249" mass="27968" checksum="2B50E0A7AABA1BF0" modified="2023-09-13" version="1" fragment="single">MPRHTPTVNDDDDDAAATSHPLSTTTTTTAPPHAPTVNDDDDDAAATSHPHCQQRRCRVTPPLSTTTTTASPHTPTVNDDDNNGATSRPHCQRRRRRRRCHDTTPLSTTTTTTMPRHTPTVNNNDNGANSRPHCQQHQRRRRHRHDTPPLSTTTTTTMPRHTHTVNNDDDNTNNNDNTNNNDNTNNNDAAASHPHCQQRRQRRYLTPPPVNNTNDDDATSHPHCPQRQRQRRHLTRPLSTPTTPTNTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4A4</accession>
    <name>A0A9P6E4A4_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_118210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157952">
        <property type="protein sequence ID" value="KAF9522299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4A4"/>
    <dbReference type="OrthoDB" id="5967843at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="63"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="556" mass="63036" checksum="7FD886A56C9D27D2" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E4P7</accession>
    <name>A0A9P6E4P7_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_864394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157943">
        <property type="protein sequence ID" value="KAF9522516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E4P7"/>
    <dbReference type="OrthoDB" id="2688364at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040423289" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="492" mass="54804" checksum="F143357FAA72E044" modified="2023-09-13" version="1">MTPLNLADLYLDILVSILSLLRPAEVVTASKVCRSLRAASKTRIVWLEVTLSMMEEHGILSSTYSLVNIDTTTLKHIATSPTRLSNLIKSRAHEAELFPVAARVLLGPNQENKSLGIKEVNELHSPYLFPGGRFVFIMSDTRTQVGENKTCVQLWDLGIPGLSQRFELVAGDVFDCIFTMWTIIPDGLGSGYYIIASGEKTLHQSGTLFVYLFDPNNFKIDAKPINQLATNGGILDFSCYGTKVVAIDEVGEITAWDYKSRLAIRWKISSDMVLDENLMTLQLVDSDVFIAQKGYIFQWRIPELLDQDILGTMPRLRDPFKTFSHLYPSPLAPSPPPSAEDRTFFAPPCPWIPASQAHIAILDSDQNFGIYHMSLDLASSEGKASSIPTTPPSHLGSFPLTIRPQDKFAISELRKCDESFIFCFDEKQQPAAIHVTLEESTARAVSVVEVSLLLGVKADYFYHSLCTATGRMIFVTTEFDLFVVDYLQGPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5C6</accession>
    <name>A0A9P6E5C6_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_863933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5C6"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="70" mass="8103" checksum="46575B23A93905C6" modified="2023-09-13" version="1">MKAKTYRTKPGHVNYDDLEVIKRVEDACEAIQTGEVKNIMEASKLFTQIEKQASTWRHHGVAWASYRHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5E5</accession>
    <name>A0A9P6E5E5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CxC2-like cysteine cluster KDZ transposase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_887328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157933">
        <property type="protein sequence ID" value="KAF9522825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5E5"/>
    <dbReference type="OrthoDB" id="2682806at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1093"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9522825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1093" mass="125618" checksum="237020E64670B883" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E5T0</accession>
    <name>A0A9P6E5T0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_863675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9523000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E5T0"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9523000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="96" mass="11469" checksum="9B58D325F3DECEAF" modified="2023-09-13" version="1">MNSDRANDLGTKFHSIKEKLNILITTLLRMGLLGIIFRWDPDGHINNQIMTIYWNLCKIDGFSARKWWDLVDEESHGAIITFFRWHRIFKLHLWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E821</accession>
    <name>A0A9P6E821_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_774197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157902">
        <property type="protein sequence ID" value="KAF9524234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E821"/>
    <dbReference type="OrthoDB" id="3269685at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="33"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="262" mass="29296" checksum="DFBAE1F88E661956" modified="2023-09-13" version="1">MAGLSSAEGLQLARQLLRPQLPHPIHDYILEGVCKALDGTNVLAVLKTGGGKSGYFYGYILLITALQTLSPRCTLLKRKFPANPAMVIIFPTKGLEEEMEAKFRKLSISALAINEDTLAEARRSKRNLWKECIKDLSLLLLSPEQLSSPSFDTLIHNPSFRSRICGLGIDEVHLVHDWGDPSFREAFRNIGLVHARMPRGTTLIAVTATLLAGRETDSLLKTLNLTPGTFFFQRRSNRRNDVQDIYRVLRHGLSGWSFPDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8L9</accession>
    <name>A0A9P6E8L9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CPB83DRAFT_897979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157900">
        <property type="protein sequence ID" value="KAF9524349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8L9"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="32"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9524349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="487" mass="52348" checksum="92971B5B78321A56" modified="2023-09-13" version="1">MAEVVYNGSGDIVWKGNPDGSQDVYNIGDLSWVLSSTGNVFIMACGVGFYYSGLLRRKNALSALYASLVSVAVVILVWFIWGFSLAFSDSAGVFIGNLKYAAFTNIYLQPATESTKIPMSLYALYEMMFAATTAVIAVGALAERGRLGPLPIFIFLWVTIVYCPVACWTWNTHGWGRKLGVLDFAGGIAVHIVAGATSLAMSLYLGPRLQSTANEPWQMHNISGVILGTVLMWYGWFGFNGGSSLSANLLAVQALINTNLAAAAGGLAWVLMDYRMHEAWGSVSFCAGVISGLVTITPGSGYVSAPAAVLFGFLGGIICNLSTYLKRYGRYDDSLDIFATHAIGGLLGSLLTGIFAQSNIYSRAGTGATAKLGWLDGNWKQVPIQLAASTAALVWAFAWTYSILKLMSRLSFTKMRASREAQETGLDEHQMHEAAFNVSDYPTILEVNKHVVSTVQNMRNAPGRVRTIDDLNMAQNAQRPPVGAAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E8V9</accession>
    <name>A0A9P6E8V9_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_860634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157892">
        <property type="protein sequence ID" value="KAF9524873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E8V9"/>
    <dbReference type="OrthoDB" id="3244370at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="707" mass="78219" checksum="558BBA49B0CB7DFE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6E912</accession>
    <name>A0A9P6E912_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_860322</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157890">
        <property type="protein sequence ID" value="KAF9524966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6E912"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="96"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="96"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="267"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="549"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="599"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="649"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9524966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="699" mass="77768" checksum="3902E5A0866FBB4E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA36</accession>
    <name>A0A9P6EA36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_897285</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA36"/>
    <dbReference type="OrthoDB" id="438939at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000073">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000088">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000329">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="9">
        <location>
            <begin position="184"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="10">
        <location>
            <begin position="938"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1158" mass="129234" checksum="A03CC0E51E7D30DE" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EA60</accession>
    <name>A0A9P6EA60_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein YTP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_860057</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157888">
        <property type="protein sequence ID" value="KAF9525129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EA60"/>
    <dbReference type="OrthoDB" id="4137487at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018827">
        <property type="entry name" value="YTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685:SF2">
        <property type="entry name" value="PROTEIN YTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10355">
        <property type="entry name" value="Ytp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040119679" description="Protein YTP1" evidence="3">
        <location>
            <begin position="26"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2427" evidence="4">
        <location>
            <begin position="29"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Protein YTP1-like C-terminal" evidence="5">
        <location>
            <begin position="154"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="56022" checksum="9BE2FB499EB1D35E" modified="2023-09-13" version="1">MKSKVLNSALRTGFLLSCIATFVVAHEHHDEVTEEEEHAPIDTILWLHIFLQAAVWGILFPIGMVLGLSRSRWHIPLQATGFLLTLGGYILGHSHKGRAFPASAHGKFANIMVIPILTQLVVGIYLKLHIHEKSIRPYFVVLHGILGKCYPILAWLQMLFGAVVFRGYCRGGHLGQCLAHYIMGSGFIAYAVLMAITLVAGEQWMRRSGRSPEFFDSWVIMAWGVVNTFTEHHGGAWSVKDMQHTILGVLWWAGGLLGIYLSRNNQRNVVPGLIICLTGWAMAGHAQALMISTMVHAMFGYTLILAGFTRIIEVCFFVPSYAPLPADHAEDDNTSEHTLAEGGPSRNPTSMKSAAAKNWRHLPPFLLVASGLLFMSATDEELRFVHSQEMDHVTYILIFFSLAFLIYAFILFLINLYLTTGRNAASNANGVVINSVDESNIEMITPSGNSKWYSRVPSGAAPARAGGAVRLEGGNASLGGGVHVLGDDDDDEDELAPSQPQIHKGRGTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EAN0</accession>
    <name>A0A9P6EAN0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_859401</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157883">
        <property type="protein sequence ID" value="KAF9525520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EAN0"/>
    <dbReference type="OrthoDB" id="14603at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9525520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="127" mass="13435" checksum="82B8E49F4EB0761D" modified="2023-09-13" version="1">MSSNSGSEAQPGTHLPSRLPAPTGNILHDSIESAKHVSDLPCARNALLAGIASGTGMGVIRGLSTGPMMAGNWAIATFIVISLGSWHICQQQFSNERKKIAQVFEATMPKRTLKESPSFGSNQDKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EB90</accession>
    <name>A0A9P6EB90_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_908901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157879">
        <property type="protein sequence ID" value="KAF9525792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EB90"/>
    <dbReference type="OrthoDB" id="2788229at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9525792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="469" mass="52184" checksum="A9F162D9C5C5391A" modified="2023-09-13" version="1">MSRVIPTAIRSAIPCLVLGPNPPSLAMNSQIPQEIVNAIVDNLSCKAVDRTSLLACTLVSQSFSGPARRHLFSTISIRWKQNKSVEAQVRQLLSMISSRSDLRFLVRSLLIEDLGHNRSNPSVARAMDDTSDLFNLLQALTGVHSPLRALYLYCYSTSTNLYTSWQDIGVQTRSALMSIFPQLTFLRLREVREVPFTILKDMPLMETLELCQVSLEGEDEKSTLCKLGRVDTIDSLRRVTSLRVDGGLSKLLEYSTAAGLDFPKMKLFRTLVSDSEDIHAVWNLTQKFDSMNSLEMKLYTDCSYMSHSPVDLGRLSHLQSLCIRLCPLRASDNEALPHAFNLLYPPTRPTSLSTLKIVLSSPYILSSAEDFLPEQIGSSWAVLHPEKLLDVHPTLTSVEVEVDLSQSAVKWTHAPNVRPPSKAQVLSSLTKRLQKSIFGSEDPISSSSSFEKPMNIITFSLKAPGCLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EBA5</accession>
    <name>A0A9P6EBA5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_877071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157878">
        <property type="protein sequence ID" value="KAF9525850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EBA5"/>
    <dbReference type="OrthoDB" id="5232919at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09998">
        <property type="entry name" value="HDAC_Hos3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053244">
        <property type="entry name" value="HDAC_HD_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47558:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE HOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="127"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9525850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="639" mass="68624" checksum="4EAE1DA8E39A4B8C" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EC78</accession>
    <name>A0A9P6EC78_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trehalase</fullName>
            <ecNumber evidence="5">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_908486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="5"/>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EC78"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="6">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9526380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="786" mass="89814" checksum="D8F970FCA61BD9E3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECE3</accession>
    <name>A0A9P6ECE3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_857932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157872">
        <property type="protein sequence ID" value="KAF9526333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECE3"/>
    <dbReference type="OrthoDB" id="545910at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051747">
        <property type="term" value="F:cytosine C-5 DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF1">
        <property type="entry name" value="DNA OXIDATIVE DEMETHYLASE ALKBH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="133"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR632852-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="30505" checksum="C5449E0A143BD246" modified="2023-09-13" version="1">MERQSKPQKISKQKEEESDSTGKSEAFRQVTSSKFDAFKIQDMPDCDVYYVPSLVTKKKSDEWYTSLLELDSWYQPTLKVYGKEVTQSRKIAAYSTDPKLTLKYSGQTVDMKYEYPLLLRTIQDEVEEYLGVKFNHVMLNLYEDGTVYIGNHRDNPENKVIASLSLGAERTFVMTHDSKTKKTIKKAATTELSTSKKGKRKAETLQDSTPSSTESSVSVLQKRWILGSGSLVIMQGDTQKFWKHEIPKEAKIKGGRISLTFRQLVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECJ0</accession>
    <name>A0A9P6ECJ0_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL39</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L39</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_770078</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECJ0"/>
    <dbReference type="OrthoDB" id="6332053at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein-like L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_eL39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002316">
        <property type="entry name" value="PRK01242.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="50" mass="6188" checksum="34378FB771EFD52D" modified="2023-09-13" version="1" fragment="single">PSQKSFIIKKRLAKAARQNRPIPQWFRLKTDTKIQYNAKRRHWRRTKLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ECN8</accession>
    <name>A0A9P6ECN8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_857729</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157870">
        <property type="protein sequence ID" value="KAF9526555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ECN8"/>
    <dbReference type="OrthoDB" id="549788at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9526555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="226" mass="25797" checksum="76316EACA6321289" modified="2023-09-13" version="1">MSSIDCAMCNNPATLRCSACRCSPIYCSKPCQLADWKLHKNLCKSRPSFETPPTPESRRAIVFLESGEIKFTWETTCMKTDEDDGTIWESPTGLEKYFGGQRPKIQPYYNNVIRNRRLKEHIDLRFNDNFLLDGSPKNLAVCKVVEGMDNGGAVWRGALVALKQTNTWLNKERTLGNESPGFGHMDLGDFREVVDYLTNWKRNADTDPETRQRQSQKAFEAMMKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDG2</accession>
    <name>A0A9P6EDG2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_394877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDG2"/>
    <dbReference type="OrthoDB" id="78858at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019152">
        <property type="entry name" value="DUF2046"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15276:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15276">
        <property type="entry name" value="H4 D10S170 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09755">
        <property type="entry name" value="DUF2046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="576" mass="61823" checksum="47DAEAEE133CD694" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EDJ8</accession>
    <name>A0A9P6EDJ8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glucanase</fullName>
            <ecNumber evidence="10">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_895563</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="10"/>
    <dbReference type="EMBL" id="MU157864">
        <property type="protein sequence ID" value="KAF9527136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EDJ8"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876:SF10">
        <property type="entry name" value="GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 10" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040539833" description="Glucanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 9">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9527136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="400" mass="43763" checksum="3840F9643B48ADD0" modified="2023-09-13" version="1">MVVLRTFLAGIVFVPLAALSTPATTRDNVNPYIGKNAFANKGYAAKLEATIDYFNAQSDKPNAARTKLVQKIPTFSWLSYSVDVPGIKGLVADALQAQTTSSQKQVVQLVVYNLPDRDCSAKASDGEFHLIDDGLNKYKAFIDAIFAQLTTIDAKKLDFVLIIEPDALANVITSMDFEKCRNAASAYKEGIRYAITKFQLPNVALYLDAGHGGWLGSSEELEPTAQLFAQVLKSAQKSSPATQVRGLAINVSNYNQYIAPVRENYTEGSPSWDEFHYVNSLLPRLKNAGYPTHFIVDQGRAGKAGIRTGWEEWCNLQNAGFGTRPTSDQAVLKNDYVDSIVWVKPGGESDGTSDKNSVRFDNNCVSPVAHIPAPEAGQWFNEYVVNLVKNAEPPLEPSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEC9</accession>
    <name>A0A9P6EEC9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_814822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEC9"/>
    <dbReference type="OrthoDB" id="3203574at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="209" mass="22446" checksum="932CBB8238C41FD9" modified="2023-09-13" version="1">MFPVPSNYPSQQPATVFSPSIPPIPPSIPYNSGTLAHGPSDATGYSHQYLSHNSLNGYLSQSQDTLLSGPDMNSPDAFRENIHTALGEVEKLQLLARTVLTSIQSAYQPGIAPHHTEANITRLQEQLALTIEILRQSGVGALPLAATSPRSGSAAPMQPIPSEPVLLESVTRNLEIFYDQLQRRQESAGVVVNLLGTEREKAGVTVVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EEI8</accession>
    <name>A0A9P6EEI8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transport protein Avl9-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_855890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AVL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157860">
        <property type="protein sequence ID" value="KAF9527500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EEI8"/>
    <dbReference type="OrthoDB" id="26278at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018307">
        <property type="entry name" value="ABL9/DENND6_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051731">
        <property type="entry name" value="DENND11/AVL9_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017:SF1">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09794">
        <property type="entry name" value="Avl9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="174"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="660"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="768"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="698"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9527500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="866" mass="93550" checksum="130C33B02C6E5438" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EF42</accession>
    <name>A0A9P6EF42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CPB83DRAFT_792535</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157857">
        <property type="protein sequence ID" value="KAF9527932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9527932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="504" mass="57452" checksum="ABB0E157B0558CD1" modified="2023-09-13" version="1">MEAPSLQWMLIDGFSCAICLYVFKEKWLTSSKPPYPPGPTDQSWFTGNLSDFPVEAIWLKFTEWADEFGDIVHLRVLDKHSIIVNSLDVAKELFEKRSNIYSSRPPSAMVDLMGGEFITPLKTYGDDWRLERRMFQQFFKPDVLQQYQDVQTRKINDLLSKLLVTPDDFLDHIRYSIGAVIMSIMYDHEVASQDDRFIKVAETANQKFAIGSTPSVFLVNVFPILRFVPAWFPGAGFKLFAREASLLAQQMLNDPIDMVRERMKSGEGLPCVASELLEMYHTERDLKNVLSMCGSGYSAGTDTSVSVIQTFFYAMIRFGDVQVKAHEEIDKVLGGDRLPKFEDRAALPYIEALLRELLRWHPILPVGIMHYTTEEDIFQGYFIPKGTTFFPNVWAMSREPNKYEDPNTFNPSRFLDNNGSLNDDDVGYAFGFGRRICPGCYFASATVWLAVVSILASFEIRKKKDASGQELPVDVHFSTDSILSHPSHFNARLYLVQRALKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFB7</accession>
    <name>A0A9P6EFB7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_907317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157858">
        <property type="protein sequence ID" value="KAF9527709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFB7"/>
    <dbReference type="OrthoDB" id="3195323at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="668"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="736"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="904" mass="96784" checksum="B8DAD591420A1D3E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFE3</accession>
    <name>A0A9P6EFE3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_767409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9528082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFE3"/>
    <dbReference type="OrthoDB" id="3197626at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="313" mass="35131" checksum="AF3A414E24F48FF9" modified="2023-09-13" version="1">MVDWNSEPVQKRGAEAFIKYVHALTGLYIMEVIVTGDAEWGVLTGTKKFRWPMVCCVPRAHDHATIVVIHLIILLLHYRTTSDCRPMLAVSLFLTHSSLGMNSINFAIRTIAIYDWNARITGGLTALIVGHWTVIFLVETSQVGFEGSPGDGCIHTMTSVGLSWIRAVYLYTLCVDFVVIVLTVWKVRNLARSHGSVAQVVVSQNVFYFFIAQVFFFYSSARFMMLMHWFLDRFILDLLAIIVMSLTYNIGLIALFTSTATIVTTVKTPVNGFKGAYSQSKDYCLQSCSIALHPHGSSNQQLHIYLFSTVVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EFI6</accession>
    <name>A0A9P6EFI6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_855098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157856">
        <property type="protein sequence ID" value="KAF9527967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EFI6"/>
    <dbReference type="OrthoDB" id="3262423at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="687" mass="75800" checksum="D33CEF8653CE5B25" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGJ5</accession>
    <name>A0A9P6EGJ5_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_894379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157853">
        <property type="protein sequence ID" value="KAF9528339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGJ5"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475">
        <property type="entry name" value="ZYGOTE-SPECIFIC CLASS V COPY B GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37475:SF1">
        <property type="entry name" value="ZYGOTE-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040497678" evidence="1">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9528339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="8090" checksum="55D625A96CA43C09" modified="2023-09-13" version="1">MRFNTAATLAILAATTSSVMGGPLSYGLCQTGCNTVAVACYAAAGCVFGTVVAAAAAPAAVLGCNAALGTCSATCATLVLFAPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EGK9</accession>
    <name>A0A9P6EGK9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_883472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157852">
        <property type="protein sequence ID" value="KAF9528507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EGK9"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="433" mass="49840" checksum="BE668ABE642D1BE4" modified="2023-09-13" version="1">MLYNETNEKWHVKRYMTYLPHSGFHNQRIAFENALVLAYALRRTLIIPPIRLGNKPIRYVEYDTLVMHHELSTKDGLQHCLQVPSAVSSPLECLGYFTWTTVPWIWLVNLTMISNVQPLLHLPSSSQHWFRQQFNLTDDDIEVLRDETPYQFRFLDTDTDSSPPTDRYSQDVHISDLATSNATLLQFGTLFGTSRLRLRDKVQLDYQRLIRENMAITNQDLTKVVRFIALQLQDDFVSVHLRAGDGHFKHEVSATVNNVWRKLLRDVMHFSDVTICDFAREVTGTDVLHCSTGQQRFGNCTAPLTTPKSLASKRSIDTLQCRSTLHQNTAYTGFNMPLYVATDLRDPEIHPDLELFRITFPCIFFLNDFLPALQPLKALRSPYDGVDLYPFLLPLVDGMVASEALRFVGTEGSTFSKFVMNLWKNDHEIPGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EHQ4</accession>
    <name>A0A9P6EHQ4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_283442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EHQ4"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="140" mass="15955" checksum="624D3F3995DA3B84" modified="2023-09-13" version="1">MRHPISTISHLFNSPQARSRIPDVRDLTVFSSQRSFLGKFSESHLAIIDQHHNCGFYRILPISHCMANITRAPSTLLVHRGTHFLNIQPVDKYGLLDIQKCDKSFIFSFDEVNRTEPVVIRITESDPAGAITVVEVEWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EI34</accession>
    <name>A0A9P6EI34_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_282773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157848">
        <property type="protein sequence ID" value="KAF9529074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EI34"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="68" mass="7544" checksum="AC1094B8C380F4AB" modified="2023-09-13" version="1">MLACSKQARRLDEAHEAYQSAMRDHATICCFHVNDVVNSRAINPVRKKDKLTQANGLVPGLVLGHRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIA9</accession>
    <name>A0A9P6EIA9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_852368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157845">
        <property type="protein sequence ID" value="KAF9529590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIA9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="53" mass="6082" checksum="5679099F751A379D" modified="2023-09-13" version="1">MSCAVGSMSAWSLPLTARALVKRHVHLYHHFKRQFLSKQLVISPQLRLGDPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIF2</accession>
    <name>A0A9P6EIF2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_892867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157841">
        <property type="protein sequence ID" value="KAF9530258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIF2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="136" mass="14896" checksum="96BA8C065E6C4FAF" modified="2023-09-13" version="1">MDARLDDKTSSIVTRKSDGGSPTQPRKRQGDESKKVAGTLQSIDETKFAAVFIIDKIRYLFTARLNKATDKPFRVSSATLTFRNLQGLLRSTTFQGTLGPSTMEFAFDSGPTIAGNLDEKLTEGKSVVGTGKWTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EIX8</accession>
    <name>A0A9P6EIX8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_905852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157844">
        <property type="protein sequence ID" value="KAF9529738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EIX8"/>
    <dbReference type="OrthoDB" id="3044457at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9529738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="267" mass="28454" checksum="0A9DBDC4FCEEBF16" modified="2023-09-13" version="1">MGRFFQTMAQSKIYDLAKLESFPGLLAALEAFFTLQADGDDSKASRCPVLKTYLRAKQRLQTFDRHTAFLPESVSLLNMQFITAIVAVAALVSHTNAMAVRSDACADVCQTIKPECSADTTARGFEGCWGCCEPLTTISPSDNQRYYSDVFTMRFFISAVAILSALALNVSAGVVCTAVCRPEKPVCPAGQAPGGSEGCWGCCAPIYSPGPIVSKPVVSPTPAIDTRQDSGGDGVVCTKECKLVKPVCPYNQKASGFEGCWGCCVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ42</accession>
    <name>A0A9P6EJ42_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_241123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ42"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9529889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="222" mass="24834" checksum="B2DF7E1AE32C59E2" modified="2023-09-13" version="1">MLSAYEDLAAKDLAETQTLLCRAESLVRQYCKGFFAKGHNIAAEDISGALLRHVTARPGIGYMATAIIACEEYKEPQRPDFLATLAGVWLIQLLLPLKEAGTKKVYLRPEEKTPTQDKTATLLERSGEGDLKAHRFILRYRQGERCPLSGAYTDDASPEIMEEEICSPLRTTRFLPVSSNEFNKGSPTVSQLAFCLLSHWLYFKESGTRFAHLEHALRVGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EJ85</accession>
    <name>A0A9P6EJ85_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acylaminoacyl-peptidase</fullName>
            <ecNumber evidence="5">3.4.19.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Dipeptidyl-peptidase V</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CPB83DRAFT_925297</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide.</text>
            <dbReference type="EC" id="3.4.19.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.1" evidence="5"/>
    <dbReference type="EMBL" id="MU157843">
        <property type="protein sequence ID" value="KAF9529900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EJ85"/>
    <dbReference type="OrthoDB" id="43744at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008242">
        <property type="term" value="F:omega peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045550">
        <property type="entry name" value="AARE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF4">
        <property type="entry name" value="ACYLAMINO-ACID-RELEASING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19283">
        <property type="entry name" value="APEH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylamino-acid-releasing enzyme N-terminal" evidence="11">
        <location>
            <begin position="22"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="10">
        <location>
            <begin position="554"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9529900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="786" mass="85778" checksum="9FD94625E56536BD" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EKS4</accession>
    <name>A0A9P6EKS4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_849911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157837">
        <property type="protein sequence ID" value="KAF9530946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EKS4"/>
    <dbReference type="OrthoDB" id="3067611at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9530946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="670" mass="74057" checksum="DDD50C5905AA37C9" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELE2</accession>
    <name>A0A9P6ELE2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_833669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157836">
        <property type="protein sequence ID" value="KAF9531059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELE2"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24655" checksum="DF22EE2FCA8395FB" modified="2023-09-13" version="1">MANKEAALIVKRKDDVYQRCQLLDFESWASFGILHYEVSQSRSFSLNLEGDENAPVVLIDTPGFDNNNEILPGQSRLAGIIYLERVSHPRKVPKLGEEFKKTTRKIRGFCEDQSTAKVVIATTFWDKVSGLVREKELEAHFLRPSLMESIVKMMRQNRGRETALEIVSMILKKEEQARRNQMDQLAVRVDQPASSRKTSAAQEFIRIIKGLLRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ELJ7</accession>
    <name>A0A9P6ELJ7_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_761302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ELJ7"/>
    <dbReference type="OrthoDB" id="3267993at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9531351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="85" mass="9105" checksum="55CCDCD3821A82FD" modified="2023-09-13" version="1">MTNNNNGASIVALPSVSSSLHALPHATSIHNVNIHQHMYANRAAESQAKLQKALSKTASSTSQAQPATYQPVSLVRLHRSNATIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EM33</accession>
    <name>A0A9P6EM33_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_833314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157834">
        <property type="protein sequence ID" value="KAF9531636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EM33"/>
    <dbReference type="OrthoDB" id="3062477at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="604"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="611"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9531636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="637" mass="70388" checksum="F0FC4DBAFF72BC17" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EMW8</accession>
    <name>A0A9P6EMW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_881563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157835">
        <property type="protein sequence ID" value="KAF9531534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6EMW8"/>
    <dbReference type="OrthoDB" id="2269034at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9531534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="18051" checksum="CE45108C2FBA8E4D" modified="2023-09-13" version="1" fragment="single">MVVDLHHCFLHKATVLEKCPKNREGFCLGCKKLMAIHAKIDALNRAVEDLLEEERQLSPTLNDYHDPFTTRLPVEIASSIMYLSLPASPSLQIFHRGFEEKRHIRALVNLGLVSGNWRRISRGEPKLWTILPITIGGGIDPGTSWIREWIERAGGLDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ENM5</accession>
    <name>A0A9P6ENM5_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_848013</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157833">
        <property type="protein sequence ID" value="KAF9531909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ENM5"/>
    <dbReference type="OrthoDB" id="191979at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="462"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9531909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="55969" checksum="60FBD021476E9CC2" modified="2023-09-13" version="1">MVLRILEVLYTSYWPKDYTVHIIIGLLAAYVLRTVAQGRKTNRERDLHARVVLMTGAFTPLGLTILQSLAQQGAHIIALCQEPVDSTHITLLIDILRTTTSNEQIYAEECDLKSPTSIRAFCTKFLTGKEQRLDAIIFGHEHRHIGSPWPFSNATIDRDQKERDSGSLASFLITTLLLPALLVAPVERDIRIINVVNPFYAAAGGLPFSPSFSYEIPAAQANSLFLREGQRSLRTIVLTRHIQRVLDALPTSSQIPKTEEGSSAVPIVSSKHQKSNITSVSVSPGIGRVDTISSFLSADWKSPKGFSYFGILLYIMLQPLFLMLLKSPYAAMQTVLHALYLPTPFKILAQTTVVSQNKEAQKSEGPIDVSELDMPEEVLLPGSLYAECASVKIDVKIPQEVLDKDQEDKDKRAEIKTRDKGKAKEKTPLQEEVLEIEDDGEYGGEVGGRLVWESYEQALKIWEKETPPTERDIEREQLDKEKKHSNPESPPPPVDIDQAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQ63</accession>
    <name>A0A9P6EQ63_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_890537</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="F-box_SpPof1-like"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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    </dbReference>
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        <property type="entry name" value="F-box_dom"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_PAC1"/>
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    <dbReference type="InterPro" id="IPR036322">
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        <property type="entry name" value="WD40_rpt"/>
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        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
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        <property type="entry name" value="FBOX"/>
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        <property type="match status" value="7"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF50978">
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        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS50181">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
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        <location>
            <begin position="248"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="437"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="619"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="659"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="701"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="104"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="323"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="500"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="547"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="780"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="930"/>
            <end position="951"/>
        </location>
    </feature>
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        <location>
            <begin position="981"/>
            <end position="1359"/>
        </location>
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        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
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        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
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            <begin position="341"/>
            <end position="351"/>
        </location>
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            <begin position="352"/>
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        </location>
    </feature>
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            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
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        </location>
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        </location>
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            <begin position="1143"/>
            <end position="1189"/>
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            <begin position="1300"/>
            <end position="1323"/>
        </location>
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            <begin position="1349"/>
            <end position="1359"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9532872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1359" mass="145268" checksum="4A3B8AC7673B1A9A" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6EQH8</accession>
    <name>A0A9P6EQH8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_846458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157830">
        <property type="protein sequence ID" value="KAF9532839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9532839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="25931" checksum="E7EB13918B981B7A" modified="2023-09-13" version="1">MQELKPPFLIVFQPFNSDLSMFSAFKVLFLAPALLCIVFAQSEKSLISKKPLAVPKTDFNVTSLGVQGNGCPAGSVYYTFNYELSTITINFSQFYAEVGPGIPISQNRKSCYLTIGTSVSPGLTFGLPSVGYRTYSPLDPNVTSNHTTIYYFEGQIIQATANSRLTGPIETPYKWQDDFHPLMAVVAPCGVPSNLYVATNVAVSNVKNPRGGVLTPDCEISCDYQIELNLELKKCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ER97</accession>
    <name>A0A9P6ER97_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_890341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157829">
        <property type="protein sequence ID" value="KAF9533229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ER97"/>
    <dbReference type="OrthoDB" id="2970937at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9533229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="133" mass="15139" checksum="053D6D460C931CDC" modified="2023-09-13" version="1">MNDPELLSNPLPKLLILDELDECDSDTPIVQQHILEILGKPTGNSDNLHLRGARDHGLHIGLPNNEDAAVDIASYVIDELDKIKRTHHMRAYLPVAWPSDEEVNMIVQRSSVQFIFEATLVRYIKAYNHKPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERR2</accession>
    <name>A0A9P6ERR2_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dehydrase and lipid transport-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CPB83DRAFT_755070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERR2"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="4">
        <location>
            <begin position="48"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9534893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="207" mass="22910" checksum="26C0D8C98E5AE49E" modified="2023-09-13" version="1">MLLSSTTFRSLPTLSTCCRRNLFSLPNLSSFSPFESKSKTYHEERVLPYTEKELYAVVADVASYPKFIPFCTGSRIDASALTRAMKSKTVTEAELTVGFMSFQESYISTVTCVPFKSVQAVASSSTPLFTNLSTIWKFQSNSSTRLLSKLSDTPDDPPGPTLVSYDLTYEFANPLHAAASATFFSQVAGMMIKAFEDRCRTVYGPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ERW9</accession>
    <name>A0A9P6ERW9_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_407364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157827">
        <property type="protein sequence ID" value="KAF9533742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ERW9"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040207272" evidence="1">
        <location>
            <begin position="23"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9533742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="118" mass="13774" checksum="C7D76B2FC11AD029" modified="2023-09-13" version="1">MPRSQSHTWLHLASNILHLRLAMPLSGHTIRSTTTYYHCTTTFNHSSVMAENRLGGNIESILKRRELRLYPEITAKFSHLVLFFYSCNIRMVNAPIPRRRLQLSEISSPFLFYDTHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES29</accession>
    <name>A0A9P6ES29_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Elongation factor 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Eukaryotic elongation factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CPB83DRAFT_805705</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157828">
        <property type="protein sequence ID" value="KAF9533634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES29"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000002">
        <property type="entry name" value="mRNA export factor elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 18" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="HEAT" evidence="15">
        <location>
            <begin position="193"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="451"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="696"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="996"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1041"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00050045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAF9533634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1060" mass="116509" checksum="4736166CCA6755CA" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ES98</accession>
    <name>A0A9P6ES98_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_338490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157826">
        <property type="protein sequence ID" value="KAF9534480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ES98"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9534480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="153" mass="16936" checksum="C3ECFBA40C2C6D0E" modified="2023-09-13" version="1">MHCTIEYRMRSCRLSFSNTTLLYQMNPSRINSDAVSANITRSTSSKTPLSAGFSNLKSVLQQNIDISKTCLDQLQATNSNVESDSSEASSELFQNLLDETGQVAAMIAGNGQRQGSKENLSYAVEISEVNQCIHEDRLLNIKETLEGLKIHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETA8</accession>
    <name>A0A9P6ETA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Chorismate synthase</fullName>
            <ecNumber evidence="4 8">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CPB83DRAFT_34774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8"/>
    <dbReference type="EMBL" id="MU157824">
        <property type="protein sequence ID" value="KAF9535796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETA8"/>
    <dbReference type="OrthoDB" id="1721239at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.150.10:FF:000004">
        <property type="entry name" value="Chorismate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9535796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="406" mass="43191" checksum="39FE12CCC015AB90" modified="2023-09-13" version="1">MSTFGQIFRVTTYGESHGASVGAIVDGCPPGLPLGEADIQVQLSRRRPGQTNLATPRNEKDAVHVQSGIEMGVTLGTPIGLLVKNEDHRPHDYSETDLYPRPSHADYTYLEKYGLKASSGGGRSSARETIGRVAAGAIAEKYLKLAYGVEIVAFVSSVGKIHLPSSVAPLDSTDEENDAATDALSPEFLKLLATISREEVDKQPTRCPHPETAEKMTQRIIRAKDAQDSIGGTVTCVIRNIPPGLGEPVFDKFGAVLAHAMMSIPATKAFEVGSGFRGTEVPGSKHNDPFTRGENGRLKTSTNWSGGIQGGITNGENIYFRVGFKSPATISQAQETAQYDGTPGSLAARGRHDPCVVPRAVPIVEAMAALVTIDLLLQQNARKAATSLLPAVTTLPPTMVLPKKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETF6</accession>
    <name>A0A9P6ETF6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED18</name>
        <name evidence="9" type="ORF">CPB83DRAFT_222520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ETF6"/>
    <dbReference type="OrthoDB" id="10018982at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019095">
        <property type="entry name" value="Mediator_Med18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13321:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13321">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09637">
        <property type="entry name" value="Med18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9534936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="201" mass="22835" checksum="67CB01A333E4C5ED" modified="2023-09-13" version="1">MTALSYEVALFGEFFAHDLKAILNRITLHSESSQHFRSRELSFEPLDAQAQRDAGIEPTLLRAKKELSDANLPWELFSYLKPESVRVHPEATVRPWATTQVVGDALSFAAALGYVRRSQIYKRGYAFRKGMLLILMFQQEQIDPKTMLPIPAHADTLWEVEVKTAEPLRNTQETPLSSAIEAVLDVQLLMKGLLDLRRQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ETW8</accession>
    <name>A0A9P6ETW8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CPB83DRAFT_842950</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="MU157825">
        <property type="protein sequence ID" value="KAF9534792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901992">
        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05611">
        <property type="entry name" value="STKc_Rim15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000580">
        <property type="entry name" value="AGC protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000340">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001008">
        <property type="entry name" value="Serine/threonine-protein kinase cek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="319"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="935"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="1311"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1571"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="226"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="702"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="860"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1096"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1137"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1191"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1358"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1426"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="747"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="877"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1377"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1434"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1468"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1497"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1538"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9534792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1712" mass="187436" checksum="226785B988821478" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIA8</accession>
    <name>A0A9P6JIA8_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_752408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157959">
        <property type="protein sequence ID" value="KAF9522137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIA8"/>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9522137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="60" mass="6687" checksum="B53C77CADD3692A0" modified="2023-09-13" version="1" fragment="single">RDCVAKSADDLRLSKDDEITVLLRLPDSEGDYLGYCKGVVGQFSGQDVHFHTKLKKSVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JIY3</accession>
    <name>A0A9P6JIY3_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_777166</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157948">
        <property type="protein sequence ID" value="KAF9522379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JIY3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9522379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="551" mass="61190" checksum="F19DABBCE992BE3F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ64</accession>
    <name>A0A9P6JJ64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_864251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157940">
        <property type="protein sequence ID" value="KAF9522589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ64"/>
    <dbReference type="OrthoDB" id="2914104at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="43918" checksum="83887ED49A963338" modified="2023-09-13" version="1">MPMAVIHKTRLRYRKYEDFPKVNALPAAIICSSTPTATTIRQVRSLHMKLKEKDANHAVKDKLDRTKGDRREFRFVRVNDRLFKVPEGFFLQMSSTMQSAVGFSSNGGLTPEKPIFLVHQSEDQFKQILTAYNAFPSIDPHTLTLDHLLTISELSLHYGLKELNSWFLPAFRDLIHSAHSPLRTMPNFLFVRMMRLSLQLKDPQLIGVIQAAWANRFHIGELSAVWALIFADTHCLRDLLGHACYGYLLREHSKLETGENINERGLLSPRQVLYIKSGHISLRTYWRVVGRRPPDFECGPECVLHSHCDRVWRARWAVVLAQMPSGLSEVDPLNRLGFMLDRLKEDTIVEACVSPSCRLSALKALARQRDRLSHQLHHHFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJ71</accession>
    <name>A0A9P6JJ71_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_899169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157928">
        <property type="protein sequence ID" value="KAF9522977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJ71"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9522977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="285" mass="32583" checksum="4AE5D763F85BA497" modified="2023-09-13" version="1">MLSSGEEQGKPEAEPTSFLNFKNFIGAIWAMFIAPDEPYSKNMWQLRMWQVADGSGFARSVRYFGNFGNESAKDDTFTSKFTPATKNPIRHLPPLIGQCILPIINHASPFLYSLFVFPTLVLCPPTLPLCYHLYILRLFEVQFEGFQGSLGVLNLRTYQGRSLLPSFPLKTFATTWTQTWWAATPLDTVDDGSISESRISNLTKPTRSHHHLQCVLQHHGQFSVHHNRINGPGADFLQYEEPKPRNERVLRTRSGRRRGNGNENLRFERSNISGITVLNMMFYQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JJS6</accession>
    <name>A0A9P6JJS6_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_863488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157925">
        <property type="protein sequence ID" value="KAF9523114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JJS6"/>
    <dbReference type="OrthoDB" id="2322499at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="142"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="816" mass="93080" checksum="AEE3C7C2AC51069E" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JK47</accession>
    <name>A0A9P6JK47_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF4048 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_886844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157915">
        <property type="protein sequence ID" value="KAF9523520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JK47"/>
    <dbReference type="OrthoDB" id="3204900at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="499"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="706"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="726"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9523520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="768" mass="81164" checksum="0D05ECCC86D8EEA8" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKP1</accession>
    <name>A0A9P6JKP1_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_897845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKP1"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="242" mass="27442" checksum="D853DE733D0C83B1" modified="2023-09-13" version="1">MPPFTFQFPSPIARSIKLNSRALSVNTSKLPDSLETDRTWAEEVLQYGCFPDASASVTAPLDQWIIEHRHNLGVLADSKTLGAQPLAQLESVGCDLIAIKSVSQAHGPLQRPDVHNLYISFFLDKSLNLDYDLEDLQSPTILAARFYDLKDDKPTPAWLQLADPHIVVRETPSKAMRILTWLVNQHVNREHLDDVLNWCTRVLNVYPQRPIISNDREVDLSSYEIGDPESNDERSLKRTKMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JKX4</accession>
    <name>A0A9P6JKX4_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_838701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JKX4"/>
    <dbReference type="OrthoDB" id="3107538at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9524702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="529" mass="58355" checksum="1ADF61538C7CFDE3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL15</accession>
    <name>A0A9P6JL15_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_598986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157894">
        <property type="protein sequence ID" value="KAF9524746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL15"/>
    <dbReference type="OrthoDB" id="3248197at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9524746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="66198" checksum="6A36D24CD1D75E82" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JL32</accession>
    <name>A0A9P6JL32_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_609436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157898">
        <property type="protein sequence ID" value="KAF9524493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JL32"/>
    <dbReference type="OrthoDB" id="5569250at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040976">
        <property type="entry name" value="Pkinase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17667">
        <property type="entry name" value="Pkinase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal-type protein kinase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9524493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="154" mass="17391" checksum="9B139692238E3543" modified="2023-09-13" version="1">MIYKEVVPRFDTPLVDSCQKYRLGLREIGIPSMKSKTPRIVLSVIYDLPETTRYLYTRHSVIHRDISKNNVLIIDEDSLKAYSSAAPSVEPSGSKFPRQVFIREILTPTSDAPPTLSLLIDMDCAEIINQKNDKPKEGKSGTQSSCQERFRTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JM54</accession>
    <name>A0A9P6JM54_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="11">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CPB83DRAFT_859621</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="11"/>
    <dbReference type="EMBL" id="MU157885">
        <property type="protein sequence ID" value="KAF9525319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000029">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000371">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="13">
        <location>
            <begin position="1254"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="1980"/>
            <end position="2293"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="14">
        <location>
            <begin position="2337"/>
            <end position="2369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9525319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2369" mass="268387" checksum="93322CB90C5C5443" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JMB8</accession>
    <name>A0A9P6JMB8_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CPB83DRAFT_509907</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157877">
        <property type="protein sequence ID" value="KAF9525976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001660">
        <property type="entry name" value="NF-X1 finger and helicase protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000216">
        <property type="entry name" value="Type VII secretion ATPase EccA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000160">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="483"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="1360"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="1639"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="1919"/>
            <end position="2056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1236"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2149"/>
            <end position="2267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2294"/>
            <end position="2323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1236"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1266"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1286"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="2150"/>
            <end position="2160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="2188"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2198"/>
            <end position="2212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="2215"/>
            <end position="2227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9525976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="2411" mass="269230" checksum="491F41613073569F" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JML0</accession>
    <name>A0A9P6JML0_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_857791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157871">
        <property type="protein sequence ID" value="KAF9526427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JML0"/>
    <dbReference type="OrthoDB" id="2575000at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9526427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="237" mass="24978" checksum="BFE0A40F859DCE02" modified="2023-09-13" version="1">MIAGLSKAVTLYLAPVLALTALLLSLFAFLAPTLLLQDQVALLTVTPSTVLSQPGPSKDVDGPSVFLGVLGSCARKNNAAALNCTLPTVSPQYDLSVLPGNTANLLLSAPTASAPAFIAVAISFSFLFFISFTLISLRHKLGAKMGAILEKPLVQRLSAWVGFFSFLIGLTAFLIVRMWFGKAVQDFNSSLVVQAQQGPQLVASLGNAFTMAYVAYAFLAVPVITSLAKLNVQATKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JN36</accession>
    <name>A0A9P6JN36_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CPB83DRAFT_770692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157874">
        <property type="protein sequence ID" value="KAF9526234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JN36"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00761">
        <property type="entry name" value="Glyco_tranf_GTA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="2">
        <location>
            <begin position="621"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9526234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="1005" mass="112936" checksum="4B95DB96F5DFDBB6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JNV3</accession>
    <name>A0A9P6JNV3_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CPB83DRAFT_870215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157865">
        <property type="protein sequence ID" value="KAF9527015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JNV3"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="6">
        <location>
            <begin position="183"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="302"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="575"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9527015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="586" mass="64680" checksum="14816FADE5B9A2B6" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP68</accession>
    <name>A0A9P6JP68_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CPB83DRAFT_855041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP68"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9528182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="135" mass="15624" checksum="3F20CD791448B980" modified="2023-09-13" version="1">MTPQLTHSANTECSEQTEHRFFDYLEETACTATFLPNLRSLQFRIDYADEFDWSLLRKLVPVVAPPGSACRPLSKVNIRIYEERFQIPDEAQSDLVELINGGLDILVSDDYNLQPVNKLHPFDRLKAALEMRNYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JP88</accession>
    <name>A0A9P6JP88_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_815465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157861">
        <property type="protein sequence ID" value="KAF9527419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JP88"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="658"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9527419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="941" mass="104067" checksum="6E6C5AF3ED2B7AB3" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JPV2</accession>
    <name>A0A9P6JPV2_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6534 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CPB83DRAFT_855065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157855">
        <property type="protein sequence ID" value="KAF9528198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JPV2"/>
    <dbReference type="OrthoDB" id="2535105at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045339">
        <property type="entry name" value="DUF6534"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40465:SF1">
        <property type="entry name" value="DUF6534 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20152">
        <property type="entry name" value="DUF6534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6534" evidence="2">
        <location>
            <begin position="184"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9528198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <sequence length="322" mass="35598" checksum="E479EF7A3A383511" modified="2023-09-13" version="1">MSAVPAIPQNLIEGNHGALFIGLLVATMLYGVACAQSVIYFYRWKKDRQLFKNVVLIIWMLDTVSLLQAILTLYNWLITDYGNFLAILKPSTTALAQMFISGVSDFIVRSFFARRAFILLKGNSRSSLVPWLVASTIVILSIFMYIVGCSLGSIGFRVQSQSTVDISARMAKYVWMQYAYHITSTAVDSIIAGSLCYTLAKSRSSFKQTNNIVIQLMAFSVSSGLVTSLFALSSMVLYAVLPQYLISLAIGWIIGQLHVNSLLLSLNSRSILRERYGDLSNSGGFSHEAVSFPGRMSTQYAIPLKETRAQVNISKEVTISSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ64</accession>
    <name>A0A9P6JQ64_9AGAR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial half-size ABC transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CPB83DRAFT_852990</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Ruiz-Duenas F.J."/>
                <person name="Barrasa J.M."/>
                <person name="Sanchez-Garcia M."/>
                <person name="Camarero S."/>
                <person name="Miyauchi S."/>
                <person name="Serrano A."/>
                <person name="Linde D."/>
                <person name="Babiker R."/>
                <person name="Drula E."/>
                <person name="Ayuso-Fernandez I."/>
                <person name="Pacheco R."/>
                <person name="Padilla G."/>
                <person name="Ferreira P."/>
                <person name="Barriuso J."/>
                <person name="Kellner H."/>
                <person name="Castanera R."/>
                <person name="Alfaro M."/>
                <person name="Ramirez L."/>
                <person name="Pisabarro A.G."/>
                <person name="Kuo A."/>
                <person name="Tritt A."/>
                <person name="Lipzen A."/>
                <person name="He G."/>
                <person name="Yan M."/>
                <person name="Ng V."/>
                <person name="Cullen D."/>
                <person name="Martin F."/>
                <person name="Rosso M.-N."/>
                <person name="Henrissat B."/>
                <person name="Hibbett D."/>
                <person name="Martinez A.T."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 506.95</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="MU157847">
        <property type="protein sequence ID" value="KAF9529277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6JQ64"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000807306">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18583">
        <property type="entry name" value="ABC_6TM_HMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF648">
        <property type="entry name" value="ABC-TYPE TRANSPORTER ATR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="309"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="625"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="865"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="865"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="893"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="946"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="979"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="999"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1044"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1064"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1080"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1103"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9529277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000807306"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1115" mass="122170" checksum="B0433006DF206D95" modified="2023-09-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6JQ79</accession>
    <name>A0A9P6JQ79_9AGAR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CPB83DRAFT_854409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Crepidotus variabilis</name>
        <dbReference type="NCBI Taxonomy" id="179855"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Basidiomycota</taxon>
            <taxon>Agaricomycotina</taxon>
            <taxon>Agaricomycetes</taxon>
            <taxon>Agaricomycetidae</taxon>
            <taxon>Agaricales</taxon>
            <taxon>Agaricineae</taxon>
            <taxon>Crepidotaceae</taxon>
            <taxon>Crepidotus</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Ahrendt S."/>
                <person name="Riley R."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pang